Katherine A Hoadley

Katherine A Hoadley

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Katherine A Hoadley

Publications by authors named "Katherine A Hoadley"

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Prognostic value of B cells in cutaneous melanoma.

Genome Med 2019 05 28;11(1):36. Epub 2019 May 28.

Lineberger Comprehensive Cancer Center, The University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, USA.

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http://dx.doi.org/10.1186/s13073-019-0647-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6540526PMC
May 2019

Androgen Receptor mRNA Expression in Urothelial Carcinoma of the Bladder: A Retrospective Analysis of Two Independent Cohorts.

Transl Oncol 2019 Apr 2;12(4):661-668. Epub 2019 Mar 2.

Department of Urology and Pediatric Urology, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nürnberg, Erlangen, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.tranon.2019.01.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6403442PMC
April 2019

FOXM1 Deubiquitination by USP21 Regulates Cell Cycle Progression and Paclitaxel Sensitivity in Basal-like Breast Cancer.

Cell Rep 2019 Mar;26(11):3076-3086.e6

Curriculum in Genetics and Molecular Biology, The University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA; Lineberger Comprehensive Cancer Center, The University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA; Department of Pharmacology, The University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2019.02.054DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425951PMC
March 2019

Differences in race, molecular and tumor characteristics among women diagnosed with invasive ductal and lobular breast carcinomas.

Cancer Causes Control 2019 Jan 8;30(1):31-39. Epub 2019 Jan 8.

Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, 135 Dauer Dr, Chapel Hill, NC, 27599, USA.

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http://dx.doi.org/10.1007/s10552-018-1121-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6396692PMC
January 2019

National Cancer Institute Biospecimen Evidence-Based Practices: Harmonizing Procedures for Nucleic Acid Extraction from Formalin-Fixed, Paraffin-Embedded Tissue.

Biopreserv Biobank 2018 Aug 19;16(4):247-250. Epub 2018 Jun 19.

4 Biorepositories and Biospecimen Research Branch, Cancer Diagnosis Program, Division of Cancer Treatment and Diagnosis, National Cancer Institute , Bethesda, Maryland.

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http://dx.doi.org/10.1089/bio.2018.0046DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6080192PMC
August 2018

TP53 protein levels, RNA-based pathway assessment, and race among invasive breast cancer cases.

NPJ Breast Cancer 2018 25;4:13. Epub 2018 Jun 25.

1Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599 USA.

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http://www.nature.com/articles/s41523-018-0067-5
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http://dx.doi.org/10.1038/s41523-018-0067-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6018637PMC
June 2018

Racial Differences in PAM50 Subtypes in the Carolina Breast Cancer Study.

J Natl Cancer Inst 2018 02;110(2)

Department of Epidemiology, Lineberger Comprehensive Cancer Center; Department of Pathology and Lab Medicine, Department of Nutrition (EHA), and Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC; Dana Farber Cancer Institute, Harvard University, Boston, MA; Center for Clinical Cancer Genetics, Global Health Department of Medicine, The University of Chicago, Chicago, IL.

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http://dx.doi.org/10.1093/jnci/djx135DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6059138PMC
February 2018

Reproductive risk factor associations with lobular and ductal carcinoma in the Carolina Breast Cancer Study.

Cancer Causes Control 2018 01 9;29(1):25-32. Epub 2017 Nov 9.

Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, USA.

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http://dx.doi.org/10.1007/s10552-017-0977-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5903274PMC
January 2018

Age at diagnosis, obesity, smoking, and molecular subtypes in muscle-invasive bladder cancer.

Cancer Causes Control 2017 Jun 20;28(6):539-544. Epub 2017 Mar 20.

Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Suite 32, CVS Plaza, 137 East Franklin Street, CB#8050, Chapel Hill, NC, 27599, USA.

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http://dx.doi.org/10.1007/s10552-017-0885-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5477976PMC
June 2017

Amplification of SOX4 promotes PI3K/Akt signaling in human breast cancer.

Breast Cancer Res Treat 2017 04 7;162(3):439-450. Epub 2017 Feb 7.

Rutgers Cancer Institute of New Jersey, 195 Little Albany Street, CINJ 4558, New Brunswick, NJ, 08903, USA.

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http://dx.doi.org/10.1007/s10549-017-4139-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5334195PMC
April 2017

Genomic Analysis of Immune Cell Infiltrates Across 11 Tumor Types.

J Natl Cancer Inst 2016 11 22;108(11). Epub 2016 Jun 22.

Affiliations of authors: Lineberger Comprehensive Cancer Center (MDI, JSP, KAH, JSS, CMP, BGV), Curriculum in Genetics and Molecular Biology (MDI, JSP), Department of Medicine (JSS, BGV), Department of Genetics (KAH, CMP), Department of Microbiology and Immunology (JSS), and Department of Pathology & Laboratory Medicine (CMP), University of North Carolina, Chapel Hill, Chapel Hill, NC.

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http://jnci.oxfordjournals.org/content/108/11/djw144.full.pd
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https://academic.oup.com/jnci/article-lookup/doi/10.1093/jnc
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http://dx.doi.org/10.1093/jnci/djw144DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5241901PMC
November 2016

MR Imaging Radiomics Signatures for Predicting the Risk of Breast Cancer Recurrence as Given by Research Versions of MammaPrint, Oncotype DX, and PAM50 Gene Assays.

Radiology 2016 Nov 5;281(2):382-391. Epub 2016 May 5.

From the Depts of Radiology (H.L., K.D., M.L.G.) and Public Health Sciences (Y.J.), The Univ of Chicago, 5841 S Maryland Ave, MC 2026, Chicago, IL 60637; Program of Computational Genomics & Medicine, NorthShore Univ HealthSystem, Evanston, Ill (Y.Z., Y.J.); Dept of Radiology, Univ of Wisconsin-Madison, Madison, Wis (E.S.B.); Lineberger Comprehensive Cancer Ctr, Univ of North Carolina, Chapel Hill, NC (K.A.H., C.F., C.M.P.); Dept of Medicine, Section of Hematology & Oncology, The Univ of Chicago, Chicago, Ill (S.D.C.); Dept of Diagnostic Radiology, The Univ of Texas MD Anderson Cancer Ctr, Houston, Tex (G.J.W.); Dept of Radiology, Memorial Sloan-Kettering Cancer Ctr, New York, NY (E.J.S., E.A.M.); Dept of Radiology, Univ of Miami Sylvester Comprehensive Cancer Ctr, Miami, Fla (J.M.N.); Dept of Radiology, Univ of Pittsburgh Medical Ctr, Pittsburgh, Pa (M.G.); and Div of Cancer Treatment and Diagnosis, National Cancer Inst, Biometric Research Branch, Bethesda, Md (E.H.).

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5069147PMC
http://dx.doi.org/10.1148/radiol.2016152110DOI Listing
November 2016

Identification of mRNA isoform switching in breast cancer.

BMC Genomics 2016 Mar 3;17:181. Epub 2016 Mar 3.

Department of Genetics, University of North Carolina, 27599, Chapel Hill, NC, USA.

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http://dx.doi.org/10.1186/s12864-016-2521-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4778320PMC
March 2016

Molecular Heterogeneity and Response to Neoadjuvant Human Epidermal Growth Factor Receptor 2 Targeting in CALGB 40601, a Randomized Phase III Trial of Paclitaxel Plus Trastuzumab With or Without Lapatinib.

J Clin Oncol 2016 Feb 2;34(6):542-9. Epub 2015 Nov 2.

Lisa A. Carey, David W. Ollila, Carey K. Anders, Katherine A. Hoadley, Michael Iglesia, and Charles M. Perou, University of North Carolina Chapel Hill, Chapel Hill; Constance T. Cirrincione and Brandelyn N. Pitcher, Alliance Statistics and Data Center, Duke University, Durham, NC; Donald A. Berry, Alliance Statistics and Data Center, MD Anderson, Houston, TX; William T. Barry, Alliance Statistics and Data Center, Dana-Farber Cancer Institute; Ian E. Krop and Eric P. Winer, Dana-Farber Cancer Institute, Boston, MA; Lyndsay N. Harris, University Hospitals of Cleveland, Cleveland, OH; Norah Lynn Henry, University of Michigan, Ann Arbor, MI; Douglas J. Weckstein, New Hampshire Hematology-Oncology, Hooksett, NH; Baljit Singh, New York University; Clifford A. Hudis, Memorial Sloan-Kettering Cancer Center, New York, NY; and Maggie Chon U. Cheang, Clinical Trials and Statistics Unit, Institute of Cancer Research, Belmont, United Kingdom.

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http://dx.doi.org/10.1200/JCO.2015.62.1268DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4980567PMC
February 2016

Comprehensive Molecular Characterization of Papillary Renal-Cell Carcinoma.

Authors:
W Marston Linehan Paul T Spellman Christopher J Ricketts Chad J Creighton Suzanne S Fei Caleb Davis David A Wheeler Bradley A Murray Laura Schmidt Cathy D Vocke Myron Peto Abu Amar M Al Mamun Eve Shinbrot Anurag Sethi Samira Brooks W Kimryn Rathmell Angela N Brooks Katherine A Hoadley A Gordon Robertson Denise Brooks Reanne Bowlby Sara Sadeghi Hui Shen Daniel J Weisenberger Moiz Bootwalla Stephen B Baylin Peter W Laird Andrew D Cherniack Gordon Saksena Scott Haake Jun Li Han Liang Yiling Lu Gordon B Mills Rehan Akbani Mark D M Leiserson Benjamin J Raphael Pavana Anur Donald Bottaro Laurence Albiges Nandita Barnabas Toni K Choueiri Bogdan Czerniak Andrew K Godwin A Ari Hakimi Thai H Ho James Hsieh Michael Ittmann William Y Kim Bhavani Krishnan Maria J Merino Kenna R Mills Shaw Victor E Reuter Ed Reznik Carl S Shelley Brian Shuch Sabina Signoretti Ramaprasad Srinivasan Pheroze Tamboli George Thomas Satish Tickoo Kenneth Burnett Daniel Crain Johanna Gardner Kevin Lau David Mallery Scott Morris Joseph D Paulauskis Robert J Penny Candace Shelton W Troy Shelton Mark Sherman Eric Thompson Peggy Yena Melissa T Avedon Jay Bowen Julie M Gastier-Foster Mark Gerken Kristen M Leraas Tara M Lichtenberg Nilsa C Ramirez Tracie Santos Lisa Wise Erik Zmuda John A Demchok Ina Felau Carolyn M Hutter Margi Sheth Heidi J Sofia Roy Tarnuzzer Zhining Wang Liming Yang Jean C Zenklusen Jiashan Zhang Brenda Ayala Julien Baboud Sudha Chudamani Jia Liu Laxmi Lolla Rashi Naresh Todd Pihl Qiang Sun Yunhu Wan Ye Wu Adrian Ally Miruna Balasundaram Saianand Balu Rameen Beroukhim Tom Bodenheimer Christian Buhay Yaron S N Butterfield Rebecca Carlsen Scott L Carter Hsu Chao Eric Chuah Amanda Clarke Kyle R Covington Mahmoud Dahdouli Ninad Dewal Noreen Dhalla Harsha V Doddapaneni Jennifer A Drummond Stacey B Gabriel Richard A Gibbs Ranabir Guin Walker Hale Alicia Hawes D Neil Hayes Robert A Holt Alan P Hoyle Stuart R Jefferys Steven J M Jones Corbin D Jones Divya Kalra Christie Kovar Lora Lewis Jie Li Yussanne Ma Marco A Marra Michael Mayo Shaowu Meng Matthew Meyerson Piotr A Mieczkowski Richard A Moore Donna Morton Lisle E Mose Andrew J Mungall Donna Muzny Joel S Parker Charles M Perou Jeffrey Roach Jacqueline E Schein Steven E Schumacher Yan Shi Janae V Simons Payal Sipahimalani Tara Skelly Matthew G Soloway Carrie Sougnez Angela Tam Donghui Tan Nina Thiessen Umadevi Veluvolu Min Wang Matthew D Wilkerson Tina Wong Junyuan Wu Liu Xi Jane Zhou Jason Bedford Fengju Chen Yao Fu Mark Gerstein David Haussler Katayoon Kasaian Phillip Lai Shiyun Ling Amie Radenbaugh David Van Den Berg John N Weinstein Jingchun Zhu Monique Albert Iakovina Alexopoulou Jeremiah J Andersen J Todd Auman John Bartlett Sheldon Bastacky Julie Bergsten Michael L Blute Lori Boice Roni J Bollag Jeff Boyd Erik Castle Ying-Bei Chen John C Cheville Erin Curley Benjamin Davies April DeVolk Rajiv Dhir Laura Dike John Eckman Jay Engel Jodi Harr Ronald Hrebinko Mei Huang Lori Huelsenbeck-Dill Mary Iacocca Bruce Jacobs Michael Lobis Jodi K Maranchie Scott McMeekin Jerome Myers Joel Nelson Jeremy Parfitt Anil Parwani Nicholas Petrelli Brenda Rabeno Somak Roy Andrew L Salner Joel Slaton Melissa Stanton R Houston Thompson Leigh Thorne Kelinda Tucker Paul M Weinberger Cynthia Winemiller Leigh Anne Zach Rosemary Zuna

Bladder Cancer Molecular Taxonomy: Summary from a Consensus Meeting.

Bladder Cancer 2016 Jan 7;2(1):37-47. Epub 2016 Jan 7.

Epithelial Carcinogenesis Group, Spanish National Cancer Research Centre-CNIO, Madrid, Spain and Departament de Ciències Experimentals i de la Salut, Universitat Pompeu Fabra , Barcelona, Spain.

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http://dx.doi.org/10.3233/BLC-150037DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4927916PMC
January 2016

Oncometabolite D-2-Hydroxyglutarate Inhibits ALKBH DNA Repair Enzymes and Sensitizes IDH Mutant Cells to Alkylating Agents.

Cell Rep 2015 Dec 10;13(11):2353-2361. Epub 2015 Dec 10.

Molecular and Cell Biology Lab of Key Laboratory of Molecular Medicine of Ministry of Education and Institutes of Biomedical Sciences, Shanghai Medical College, College of Life Science, Fudan University, Shanghai 200032, China; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA; Department of Biochemistry and Biophysics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.

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http://www.cell.com/cell-reports/pdf/S2211-1247(15)01329-7.p
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http://linkinghub.elsevier.com/retrieve/pii/S221112471501329
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http://dx.doi.org/10.1016/j.celrep.2015.11.029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4694633PMC
December 2015

The Cancer Genome Atlas Project on Muscle-invasive Bladder Cancer.

Eur Urol Focus 2015 Aug 6;1(1):94-95. Epub 2015 Jun 6.

Baylor College of Medicine, Houston, TX, USA.

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http://dx.doi.org/10.1016/j.euf.2014.11.002DOI Listing
August 2015

Overexpression of miR-146a in basal-like breast cancer cells confers enhanced tumorigenic potential in association with altered p53 status.

Carcinogenesis 2014 Nov 14;35(11):2567-75. Epub 2014 Aug 14.

UNC Lineberger Comprehensive Cancer Center, Chapel Hill, NC 27599, USA, Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA, Department of Pathology and Laboratory Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA

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http://dx.doi.org/10.1093/carcin/bgu175DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4288116PMC
November 2014

Molecular features of the basal-like breast cancer subtype based on BRCA1 mutation status.

Breast Cancer Res Treat 2014 Aug 22;147(1):185-91. Epub 2014 Jul 22.

Translational Genomics Group, Vall d´Hebron Institute of Oncology (VHIO), Pg Vall d´Hebron, 119-129, 08035, Barcelona, Spain,

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http://dx.doi.org/10.1007/s10549-014-3056-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4131128PMC
August 2014

Prognostic B-cell signatures using mRNA-seq in patients with subtype-specific breast and ovarian cancer.

Clin Cancer Res 2014 Jul 10;20(14):3818-29. Epub 2014 Jun 10.

Authors' Affiliations: Lineberger Comprehensive Cancer Center; Medicine; Microbiology and Immunology, University of North Carolina, Chapel Hill, North Carolina

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http://dx.doi.org/10.1158/1078-0432.CCR-13-3368DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4102637PMC
July 2014

Integrated RNA and DNA sequencing improves mutation detection in low purity tumors.

Nucleic Acids Res 2014 Jul 26;42(13):e107. Epub 2014 Jun 26.

Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA Department of Internal Medicine, Division of Medical Oncology, Multidisciplinary Thoracic Oncology Program, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA

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http://dx.doi.org/10.1093/nar/gku489DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4117748PMC
July 2014

Comparison of RNA-Seq by poly (A) capture, ribosomal RNA depletion, and DNA microarray for expression profiling.

BMC Genomics 2014 Jun 2;15:419. Epub 2014 Jun 2.

Curriculum in Bioinformatics and Computational Biology, The University of North Carolina at Chapel Hill, Chapel Hill NC 27599, USA.

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http://dx.doi.org/10.1186/1471-2164-15-419DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4070569PMC
June 2014

Intrinsic subtypes of high-grade bladder cancer reflect the hallmarks of breast cancer biology.

Proc Natl Acad Sci U S A 2014 Feb 11;111(8):3110-5. Epub 2014 Feb 11.

Department of Genetics, Department of Medicine, Division of Hematology/Oncology, Department of Surgery, Department of Pathology and Laboratory Medicine, and Department of Pharmacology, Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599.

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http://dx.doi.org/10.1073/pnas.1318376111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3939870PMC
February 2014

The molecular diversity of Luminal A breast tumors.

Breast Cancer Res Treat 2013 Oct 6;141(3):409-20. Epub 2013 Oct 6.

Computational Biology Center, Memorial Sloan-Kettering Cancer Center, New York, NY, USA,

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http://dx.doi.org/10.1007/s10549-013-2699-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3824397PMC
October 2013

JOINT AND INDIVIDUAL VARIATION EXPLAINED (JIVE) FOR INTEGRATED ANALYSIS OF MULTIPLE DATA TYPES.

Ann Appl Stat 2013 Mar;7(1):523-542

Department of Statistics and Operations Research, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599.

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http://dx.doi.org/10.1214/12-AOAS597DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3671601PMC
March 2013

Potential tumor suppressor role for the c-Myb oncogene in luminal breast cancer.

PLoS One 2010 Oct 7;5(10):e13073. Epub 2010 Oct 7.

Curriculum in Genetics and Molecular Biology, University of North Carolina, Chapel Hill, North Carolina, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0013073PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2951337PMC
October 2010

Development of an immuno tandem mass spectrometry (iMALDI) assay for EGFR diagnosis.

Proteomics Clin Appl 2007 Dec;1(12):1651-9

Curriculum in Applied and Materials Sciences, UNC-CH, Chapel Hill, NC, USA.

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http://doi.wiley.com/10.1002/prca.200700009
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http://dx.doi.org/10.1002/prca.200700009DOI Listing
December 2007

EGFR associated expression profiles vary with breast tumor subtype.

BMC Genomics 2007 Jul 31;8:258. Epub 2007 Jul 31.

Curriculum in Genetics and Molecular Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.

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http://dx.doi.org/10.1186/1471-2164-8-258DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2014778PMC
July 2007

RNA expression analysis of formalin-fixed paraffin-embedded tumors.

Lab Invest 2007 Apr 12;87(4):383-91. Epub 2007 Feb 12.

Department of Medicine, The University of North Carolina School of Medicine, Chapel Hill, NC 27599-7295, USA

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http://www.nature.com/articles/3700529
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http://dx.doi.org/10.1038/labinvest.3700529DOI Listing
April 2007

Gene expression patterns associated with p53 status in breast cancer.

BMC Cancer 2006 Dec 6;6:276. Epub 2006 Dec 6.

Division of Biostatistics and Epidemiology, School of Public Health and Health Sciences, University of Massachusetts Amherst, Amherst, MA, USA.

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http://dx.doi.org/10.1186/1471-2407-6-276DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1764759PMC
December 2006

Prediction of toxicant-specific gene expression signatures after chemotherapeutic treatment of breast cell lines.

Environ Health Perspect 2004 Nov;112(16):1607-13

Department of Pathology and Laboratory Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.

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https://ehp.niehs.nih.gov/doi/10.1289/txg.7204
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1247657PMC
http://dx.doi.org/10.1289/txg.7204DOI Listing
November 2004

Cell-type-specific responses to chemotherapeutics in breast cancer.

Cancer Res 2004 Jun;64(12):4218-26

Department of Pathology and Laboratory Medicine, University of North Carolina at Chapel Hill, 27599, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-04-0107DOI Listing
June 2004