Publications by authors named "Katharina Rox"

11Publications

Crystal structure of SARS-CoV-2 main protease provides a basis for design of improved α-ketoamide inhibitors.

Science 2020 04 20;368(6489):409-412. Epub 2020 Mar 20.

Institute of Biochemistry, Center for Structural and Cell Biology in Medicine, University of Lübeck, 23562 Lübeck, Germany.

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http://dx.doi.org/10.1126/science.abb3405DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7164518PMC
April 2020

Labyrinthopeptins as virolytic inhibitors of respiratory syncytial virus cell entry.

Antiviral Res 2020 05 18;177:104774. Epub 2020 Mar 18.

Institute for Experimental Virology, TWINCORE, Centre for Experimental and Clinical Infection Research, Hannover, Germany; German Centre of Infection Research (DZIF), Partner Site Hannover-Braunschweig, Germany; Cluster of Excellence RESIST (EXC 2155), Hannover Medical School, Hannover, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.antiviral.2020.104774DOI Listing
May 2020

Anti-biofilm Agents against : A Structure-Activity Relationship Study of -Glycosidic LecB Inhibitors.

J Med Chem 2019 10 11;62(20):9201-9216. Epub 2019 Oct 11.

Chemical Biology of Carbohydrates , Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), Helmholtz Centre for Infection Research , D-66123 Saarbrücken , Germany.

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http://dx.doi.org/10.1021/acs.jmedchem.9b01120DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6873108PMC
October 2019

Zirconyl Clindamycinphosphate Antibiotic Nanocarriers for Targeting Intracellular Persisting .

ACS Omega 2018 Aug 2;3(8):8589-8594. Epub 2018 Aug 2.

Institute of Inorganic Chemistry, Karlsruhe Institute of Technology (KIT), Engesserstrasse 15, 76131 Karlsruhe, Germany.

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http://dx.doi.org/10.1021/acsomega.8b00637DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6644946PMC
August 2018

Glycomimetic, Orally Bioavailable LecB Inhibitors Block Biofilm Formation of Pseudomonas aeruginosa.

J Am Chem Soc 2018 02 22;140(7):2537-2545. Epub 2018 Jan 22.

Chemical Biology of Carbohydrates and ‡Drug Design and Development, Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), Helmholtz Centre for Infection Research (HZI) , D-66123 Saarbrücken, Germany.

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http://dx.doi.org/10.1021/jacs.7b11133DOI Listing
February 2018

Linoleic and palmitoleic acid block streptokinase-mediated plasminogen activation and reduce severity of invasive group A streptococcal infection.

Sci Rep 2017 09 18;7(1):11798. Epub 2017 Sep 18.

Department of Microbial Natural Products, Helmholtz Institute for Pharmaceutical Research (HIPS), Helmholtz Centre for Infection Research (HZI), Saarland University, Saarbrücken, Germany.

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http://www.nature.com/articles/s41598-017-11276-z
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http://dx.doi.org/10.1038/s41598-017-11276-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5603603PMC
September 2017

Disorazoles Block Group A Streptococcal Invasion into Epithelial Cells Via Interference with the Host Factor Ezrin.

Cell Chem Biol 2017 Feb 12;24(2):159-170. Epub 2017 Jan 12.

Department of Microbial Natural Products (MINS), Helmholtz Institute for Pharmaceutical Research Saarland (HIPS) - Helmholtz Centre for Infection Research (HZI) and Institute for Pharmaceutical Biotechnology, Saarland University, 66123 Saarbrücken, Germany; German Centre for Infection Research (DZIF), Partner Site Braunschweig-Hannover, Hannover, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.chembiol.2016.12.011DOI Listing
February 2017