Kate T Murphy

Kate T Murphy

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Kate T Murphy

Kate T Murphy

Publications by authors named "Kate T Murphy"

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BGP-15 Improves Aspects of the Dystrophic Pathology in mdx and dko Mice with Differing Efficacies in Heart and Skeletal Muscle.

Am J Pathol 2016 12 14;186(12):3246-3260. Epub 2016 Oct 14.

Basic and Clinical Myology Laboratory, Department of Physiology, The University of Melbourne, Melbourne, Victoria. Electronic address:

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http://dx.doi.org/10.1016/j.ajpath.2016.08.008DOI Listing
December 2016

Disease-Induced Skeletal Muscle Atrophy and Fatigue.

Med Sci Sports Exerc 2016 11;48(11):2307-2319

1Department of Applied Physiology and Kinesiology, University of Florida, Gainesville, FL; 2Basic and Clinical Myology Laboratory, Department of Physiology, University of Melbourne, Victoria, AUSTRALIA; and 3Medical Physiology, Department of Neuroscience, University Medical Center Groningen, Groningen, THE NETHERLANDS.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5069191PMC
http://dx.doi.org/10.1249/MSS.0000000000000975DOI Listing
November 2016

Glucose-6-phosphate dehydrogenase contributes to the regulation of glucose uptake in skeletal muscle.

Mol Metab 2016 11 9;5(11):1083-1091. Epub 2016 Sep 9.

Cellular and Molecular Metabolism Laboratory, Baker IDI Heart & Diabetes Institute, Melbourne, VIC, Australia; Diabetes & Metabolism Division, Garvan Institute of Medical Research, NSW, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.molmet.2016.09.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5081409PMC
November 2016

Smad7 gene delivery prevents muscle wasting associated with cancer cachexia in mice.

Sci Transl Med 2016 07;8(348):348ra98

Baker IDI Heart and Diabetes Institute, Melbourne, Victoria 3004, Australia. Department of Physiology, The University of Melbourne, Melbourne, Victoria 3010, Australia. Department of Biochemistry and Molecular Biology, Monash University, Clayton, Victoria 3800, Australia. Department of Neurology, The University of Washington School of Medicine, Seattle, WA 98195, USA.

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http://dx.doi.org/10.1126/scitranslmed.aac4976DOI Listing
July 2016

The pathogenesis and treatment of cardiac atrophy in cancer cachexia.

Authors:
Kate T Murphy

Am J Physiol Heart Circ Physiol 2016 Feb 30;310(4):H466-77. Epub 2015 Dec 30.

Basic and Clinical Myology Laboratory, Department of Physiology, The University of Melbourne, Victoria, Australia

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http://dx.doi.org/10.1152/ajpheart.00720.2015DOI Listing
February 2016

Phosphorylation within the cysteine-rich region of dystrophin enhances its association with β-dystroglycan and identifies a potential novel therapeutic target for skeletal muscle wasting.

Hum Mol Genet 2014 Dec 31;23(25):6697-711. Epub 2014 Jul 31.

Department of Neurology, University of Washington School of Medicine, Seattle, WA 98195-7720, USA Department of Biochemistry, University of Washington School of Medicine, Seattle, WA 98195-7350, USA and Program in Molecular and Cellular Biology, University of Washington School of Medicine, Seattle, WA 98195-7275, USA

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http://dx.doi.org/10.1093/hmg/ddu388DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4245040PMC
December 2014

Glycine administration attenuates skeletal muscle wasting in a mouse model of cancer cachexia.

Clin Nutr 2014 Jun 26;33(3):448-58. Epub 2013 Jun 26.

Basic and Clinical Myology Laboratory, Department of Physiology, The University of Melbourne, Victoria 3010, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.clnu.2013.06.013DOI Listing
June 2014

Elevated expression of activins promotes muscle wasting and cachexia.

FASEB J 2014 Apr 30;28(4):1711-23. Epub 2013 Dec 30.

2Baker IDI Heart and Diabetes Institute, P.O. Box 6492, St. Kilda Rd. Central, Melbourne 8008, Australia.

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http://www.fasebj.org/content/early/2013/12/30/fj.13-245894.
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http://www.fasebj.org/cgi/doi/10.1096/fj.13-245894
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http://dx.doi.org/10.1096/fj.13-245894DOI Listing
April 2014

Inhibition of the renin-angiotensin system improves physiological outcomes in mice with mild or severe cancer cachexia.

Int J Cancer 2013 Sep 16;133(5):1234-46. Epub 2013 Mar 16.

Department of Physiology, Basic and Clinical Myology Laboratory, The University of Melbourne, Victoria, 3010, Australia.

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http://dx.doi.org/10.1002/ijc.28128DOI Listing
September 2013

Physiological characterization of a mouse model of cachexia in colorectal liver metastases.

Am J Physiol Regul Integr Comp Physiol 2013 May 13;304(10):R854-64. Epub 2013 Mar 13.

Basic and Clinical Myology Laboratory, Department of Physiology, The University of Melbourne, Victoria, Australia.

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http://dx.doi.org/10.1152/ajpregu.00057.2013DOI Listing
May 2013

Parvalbumin gene transfer impairs skeletal muscle contractility in old mice.

Hum Gene Ther 2012 Aug 5;23(8):824-36. Epub 2012 Jun 5.

Basic and Clinical Myology Laboratory, The University of Melbourne, Melbourne, VIC 3010, Australia.

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http://dx.doi.org/10.1089/hum.2011.210DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3413902PMC
August 2012

Disruption of muscle renin-angiotensin system in AT1a-/- mice enhances muscle function despite reducing muscle mass but compromises repair after injury.

Am J Physiol Regul Integr Comp Physiol 2012 Aug 6;303(3):R321-31. Epub 2012 Jun 6.

Basic and Clinical Myology Laboratory, Department of Physiology, The University of Melbourne, Victoria, Australia.

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http://ajpregu.physiology.org/content/ajpregu/303/3/R321.ful
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http://ajpregu.physiology.org/cgi/doi/10.1152/ajpregu.00007.
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http://dx.doi.org/10.1152/ajpregu.00007.2012DOI Listing
August 2012

Importance of functional and metabolic impairments in the characterization of the C-26 murine model of cancer cachexia.

Dis Model Mech 2012 Jul 22;5(4):533-45. Epub 2012 Mar 22.

Basic and Clinical Myology Laboratory, Department of Physiology, The University of Melbourne, Victoria 3010, Australia.

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http://dmm.biologists.org/content/dmm/5/4/533.full.pdf
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http://dmm.biologists.org/cgi/doi/10.1242/dmm.008839
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http://dx.doi.org/10.1242/dmm.008839DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3380716PMC
July 2012

Impaired exercise performance and muscle Na(+),K(+)-pump activity in renal transplantation and haemodialysis patients.

Nephrol Dial Transplant 2012 May 1;27(5):2036-43. Epub 2011 Nov 1.

Muscle, Ions and Exercise Group, Institute of Sport, Exercise and Active Living (ISEAL), Victoria University, Melbourne, Australia.

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http://dx.doi.org/10.1093/ndt/gfr586DOI Listing
May 2012

Editorial update on emerging drugs for cancer cachexia.

Expert Opin Emerg Drugs 2012 Mar 10;17(1):5-9. Epub 2012 Jan 10.

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http://dx.doi.org/10.1517/14728214.2012.652946DOI Listing
March 2012

Antibody-directed myostatin inhibition enhances muscle mass and function in tumor-bearing mice.

Am J Physiol Regul Integr Comp Physiol 2011 Sep 15;301(3):R716-26. Epub 2011 Jun 15.

Basic and Clinical Myology Laboratory, Department of Physiology, The University of Melbourne, Victoria, Australia.

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http://ajpregu.physiology.org/content/ajpregu/301/3/R716.ful
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http://ajpregu.physiology.org/content/ajpregu/early/2011/06/
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http://ajpregu.physiology.org/cgi/doi/10.1152/ajpregu.00121.
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http://dx.doi.org/10.1152/ajpregu.00121.2011DOI Listing
September 2011

Acute antibody-directed myostatin inhibition attenuates disuse muscle atrophy and weakness in mice.

J Appl Physiol (1985) 2011 Apr 26;110(4):1065-72. Epub 2011 Jan 26.

Basic and Clinical Myology Laboratory, Dept. of Physiology, The Univ. of Melbourne, Victoria 3010, Australia.

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http://dx.doi.org/10.1152/japplphysiol.01183.2010DOI Listing
April 2011

Antibody-directed myostatin inhibition in 21-mo-old mice reveals novel roles for myostatin signaling in skeletal muscle structure and function.

FASEB J 2010 Nov 12;24(11):4433-42. Epub 2010 Jul 12.

Department of Physiology, The University of Melbourne, Melbourne, Victoria, Australia.

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http://dx.doi.org/10.1096/fj.10-159608DOI Listing
November 2010

Update on emerging drugs for cancer cachexia.

Expert Opin Emerg Drugs 2009 Dec;14(4):619-32

Basic and Clinical Myology Laboratory, Department of Physiology, The University of Melbourne, Melbourne 3010, Australia.

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http://dx.doi.org/10.1517/14728210903369351DOI Listing
December 2009

Chronic beta2-adrenoceptor stimulation impairs cardiac relaxation via reduced SR Ca2+-ATPase protein and activity.

Am J Physiol Heart Circ Physiol 2008 Jun 11;294(6):H2587-95. Epub 2008 Apr 11.

Basic and Clinical Myology Laboratory, Department of Physiology, University of Melbourne, Victoria, Australia.

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http://dx.doi.org/10.1152/ajpheart.00985.2007DOI Listing
June 2008

N-acetylcysteine attenuates the decline in muscle Na+,K+-pump activity and delays fatigue during prolonged exercise in humans.

J Physiol 2006 Oct 13;576(Pt 1):279-88. Epub 2006 Jul 13.

School of Human Movement, Recreation and Performance, Victoria University, PO Box 14428, Melbourne, Victoria, Australia, 8001.

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http://dx.doi.org/10.1113/jphysiol.2006.115352DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1995650PMC
October 2006

Exercise performance falls over time in patients with chronic kidney disease despite maintenance of hemoglobin concentration.

Clin J Am Soc Nephrol 2006 May 19;1(3):488-95. Epub 2006 Apr 19.

Department of Nephrology, Royal Melbourne Hospital, Melbourne, Australia.

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http://dx.doi.org/10.2215/CJN.01501005DOI Listing
May 2006