Publications by authors named "Kate D Sutherland"

35Publications

Consequences of Zmat3 loss in c-MYC- and mutant KRAS-driven tumorigenesis.

Cell Death Dis 2020 Oct 20;11(10):877. Epub 2020 Oct 20.

The Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville, Melbourne, VIC, 3052, Australia.

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http://dx.doi.org/10.1038/s41419-020-03066-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7575595PMC
October 2020

NOTCH Your Usual Suspect: MYC Charged with Controlling Neuroendocrine Cell-Fate in Small Cell Lung Cancer.

Cancer Cell 2020 Jul;38(1):17-20

ACRF Cancer Biology and Stem Cell Division, The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC 3052, Australia; Department of Medical Biology, The University of Melbourne, Parkville, VIC 3052, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2020.06.009DOI Listing
July 2020

Balancing the Count: Harmonizing Panel-Based Tumor Mutational Burden Assessment.

J Thorac Oncol 2020 Jul;15(7):1106-1109

Centre for Cancer Research and Department of Clinical Pathology, The University of Melbourne, Parkville, Victoria, Australia; Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, Victoria, Australia.

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http://dx.doi.org/10.1016/j.jtho.2020.03.012DOI Listing
July 2020

Targeting platelets for improved outcome in KRAS-driven lung adenocarcinoma.

Oncogene 2020 Jul 13;39(29):5177-5186. Epub 2020 Jun 13.

ACRF Cancer Biology & Stem Cells Division, The Walter and Eliza Hall Institute of Medical Research, Melbourne, VIC, Australia.

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http://dx.doi.org/10.1038/s41388-020-1357-6DOI Listing
July 2020

Harnessing Natural Killer Immunity in Metastatic SCLC.

J Thorac Oncol 2020 Sep 26;15(9):1507-1521. Epub 2020 May 26.

ACRF Cancer Biology and Stem Cells Division, The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia; Department of Medical Biology, The University of Melbourne, Parkville, Victoria, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.jtho.2020.05.008DOI Listing
September 2020

Characterization of a novel human BFL-1-specific monoclonal antibody.

Cell Death Differ 2020 02 12;27(2):826-828. Epub 2019 Nov 12.

Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville, Melbourne, VIC, 3052, Australia.

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http://dx.doi.org/10.1038/s41418-019-0454-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7206078PMC
February 2020

Distinct initiating events underpin the immune and metabolic heterogeneity of KRAS-mutant lung adenocarcinoma.

Nat Commun 2019 09 13;10(1):4190. Epub 2019 Sep 13.

Cancer Biology and Stem Cells Division, The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, 3052, Australia.

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http://dx.doi.org/10.1038/s41467-019-12164-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6744438PMC
September 2019

Lung morphogenesis is orchestrated through Grainyhead-like 2 (Grhl2) transcriptional programs.

Dev Biol 2018 11 5;443(1):1-9. Epub 2018 Sep 5.

ACRF Stem Cells and Cancer Division, Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria 3052, Australia; Department of Medical Biology, The University of Melbourne, Parkville, Victoria 3010, Australia. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00121606183020
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http://dx.doi.org/10.1016/j.ydbio.2018.09.002DOI Listing
November 2018

"Keaping" a lid on lung cancer: the Keap1-Nrf2 pathway.

Cell Cycle 2018 1;17(14):1696-1707. Epub 2018 Aug 1.

a ACRF Stem Cells and Cancer Division , Walter and Eliza Hall Institute of Medical Research , Parkville , Victoria Australia.

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http://dx.doi.org/10.1080/15384101.2018.1496756DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6133308PMC
November 2019

FGFR3-TACC3 is an oncogenic fusion protein in respiratory epithelium.

Oncogene 2018 11 10;37(46):6096-6104. Epub 2018 Jul 10.

ACRF Stem Cells and Cancer Division, The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, 3052, Australia.

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http://dx.doi.org/10.1038/s41388-018-0399-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6215478PMC
November 2018

Synergy between the KEAP1/NRF2 and PI3K Pathways Drives Non-Small-Cell Lung Cancer with an Altered Immune Microenvironment.

Cell Metab 2018 04 8;27(4):935-943.e4. Epub 2018 Mar 8.

ACRF Stem Cells and Cancer Division, The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC 3052, Australia; Department of Medical Biology, The University of Melbourne, Parkville, VIC 3052, Australia. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S15504131183011
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http://dx.doi.org/10.1016/j.cmet.2018.02.006DOI Listing
April 2018

Combining Cell Type-Restricted Adenoviral Targeting with Immunostaining and Flow Cytometry to Identify Cells-of-Origin of Lung Cancer.

Methods Mol Biol 2018 ;1725:15-29

ACRF Stem Cells and Cancer Division, The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia.

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http://dx.doi.org/10.1007/978-1-4939-7568-6_2DOI Listing
January 2019

Lung Basal Stem Cells Rapidly Repair DNA Damage Using the Error-Prone Nonhomologous End-Joining Pathway.

PLoS Biol 2017 01 26;15(1):e2000731. Epub 2017 Jan 26.

ACRF Stem Cells and Cancer Division, The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia.

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http://dx.doi.org/10.1371/journal.pbio.2000731DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5268430PMC
January 2017

SOX2 Is the Determining Oncogenic Switch in Promoting Lung Squamous Cell Carcinoma from Different Cells of Origin.

Cancer Cell 2016 10;30(4):519-532

Division of Molecular Genetics, The Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX Amsterdam, the Netherlands; Skolkovo Institute of Science and Technology, Skolkovo Innovation Center, Building 5, Moscow 143026, Russia. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2016.09.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5065004PMC
October 2016

Polycomb Repressive Complex 2 Is a Barrier to KRAS-Driven Inflammation and Epithelial-Mesenchymal Transition in Non-Small-Cell Lung Cancer.

Cancer Cell 2016 Jan;29(1):17-31

Division of Molecular Genetics, Centre for Biomedical Genetics, The Netherlands Cancer Institute, 1066 CX Amsterdam, the Netherlands; Cancer Genomics Centre (CGC.nl), Plesmanlaan 121, 1066 CX Amsterdam, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2015.12.006DOI Listing
January 2016

Cellular Mechanisms Underlying Intertumoral Heterogeneity.

Trends Cancer 2015 Sep 28;1(1):15-23. Epub 2015 Sep 28.

Stem Cells and Cancer Division, The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria 3052, Australia; Department of Medical Biology, The University of Melbourne, Parkville, Victoria 3010, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.trecan.2015.07.003DOI Listing
September 2015

Paracrine signaling between tumor subclones of mouse SCLC: a critical role of ETS transcription factor Pea3 in facilitating metastasis.

Genes Dev 2015 Aug 27;29(15):1587-92. Epub 2015 Jul 27.

Division of Molecular Genetics, The Netherlands Cancer Institute, 1066 CX Amsterdam, The Netherlands; Skolkovo Institute of Science and Technology, Skolkovo Innovation Center, Moscow 143026, Russia.

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http://dx.doi.org/10.1101/gad.262998.115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4536306PMC
August 2015

The LIM-domain only protein 4 contributes to lung epithelial cell proliferation but is not essential for tumor progression.

Respir Res 2015 Jun 7;16:67. Epub 2015 Jun 7.

ACRF Stem Cells and Cancer Division, The Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville, VIC, 3052, Australia.

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http://dx.doi.org/10.1186/s12931-015-0228-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4475329PMC
June 2015

Multiple cells-of-origin of mutant K-Ras-induced mouse lung adenocarcinoma.

Proc Natl Acad Sci U S A 2014 Apr 28;111(13):4952-7. Epub 2014 Feb 28.

Division of Molecular Genetics, Centre for Biomedical Genetics, and Department of Experimental Animal Pathology, The Netherlands Cancer Institute, 1066 CX, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1073/pnas.1319963111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3977239PMC
April 2014

Cell of origin of small cell lung cancer: inactivation of Trp53 and Rb1 in distinct cell types of adult mouse lung.

Cancer Cell 2011 Jun;19(6):754-64

Division of Molecular Genetics, Centre for Biomedical Genetics, Cancer Genomics Centre, The Netherlands Cancer Institute, Amsterdam.

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http://dx.doi.org/10.1016/j.ccr.2011.04.019DOI Listing
June 2011

Cell of origin of lung cancer.

Mol Oncol 2010 Oct 8;4(5):397-403. Epub 2010 Jun 8.

Division of Molecular Genetics and Centre for Biomedical Genetics, The Netherlands Cancer Institute, Plesmanlaan 121, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.molonc.2010.05.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5527931PMC
October 2010

Impaired lactation in mice expressing dominant-negative FADD in mammary epithelium.

Dev Dyn 2009 Apr;238(4):1010-6

Molecular Genetics of Cancer Division, The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia.

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http://dx.doi.org/10.1002/dvdy.21917DOI Listing
April 2009

Knocking off SOCS genes in the mammary gland.

Cell Cycle 2007 Apr 20;6(7):799-803. Epub 2007 Apr 20.

Division of Molecular Genetics, The Netherlands Cancer Institute, Amsterdam, The Netherlands.

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http://dx.doi.org/10.4161/cc.6.7.4037DOI Listing
April 2007

The molecular culprits underlying precocious mammary gland involution.

J Mammary Gland Biol Neoplasia 2007 Mar;12(1):15-23

VBCRC Laboratory, The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC 3050, Australia.

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http://dx.doi.org/10.1007/s10911-007-9034-8DOI Listing
March 2007

Gata-3 is an essential regulator of mammary-gland morphogenesis and luminal-cell differentiation.

Nat Cell Biol 2007 Feb 24;9(2):201-9. Epub 2006 Dec 24.

VBCRC Laboratory, The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria 3050, Australia.

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http://dx.doi.org/10.1038/ncb1530DOI Listing
February 2007

Differential hypermethylation of SOCS genes in ovarian and breast carcinomas.

Oncogene 2004 Oct;23(46):7726-33

The Walter and Eliza Hall Institute of Medical Research and Bone Marrow Research Laboratories, Royal Melbourne Hospital, Parkville, VIC 3050, Australia.

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http://www.nature.com/articles/1207787
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http://dx.doi.org/10.1038/sj.onc.1207787DOI Listing
October 2004

SOCS3 is a critical physiological negative regulator of G-CSF signaling and emergency granulopoiesis.

Immunity 2004 Feb;20(2):153-65

Cancer and Haematology Division, The Walter and Eliza Hall Institute of Medical Research and The Cooperative Research Centre for Cellular Growth Factors, Parkville, Victoria 3050, Australia.

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http://dx.doi.org/10.1016/s1074-7613(04)00022-6DOI Listing
February 2004

Identification of Taxreb107 as a lactogenic hormone responsive gene in mammary epithelial cells.

Biochim Biophys Acta 2003 Oct;1642(3):139-47

VBCRC Breast Cancer Laboratory, The Walter and Eliza Hall Institute of Medical Research and Bone Marrow Research Laboratories, 1G Royal Parade, VIC 3050, Parkville, Australia

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http://dx.doi.org/10.1016/s0167-4889(03)00121-6DOI Listing
October 2003

Mutational analysis of the LMO4 gene, encoding a BRCA1-interacting protein, in breast carcinomas.

Int J Cancer 2003 Oct;107(1):155-8

The Walter and Eliza Hall Institute of Medical Research and Bone Marrow Research Laboratories, Parkville, Australia.

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http://doi.wiley.com/10.1002/ijc.11343
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http://dx.doi.org/10.1002/ijc.11343DOI Listing
October 2003

CPAP is a novel stat5-interacting cofactor that augments stat5-mediated transcriptional activity.

Mol Endocrinol 2002 Sep;16(9):2019-33

The Walter and Eliza Hall Institute of Medical Research & Rotary Bone Marrow Research Laboratories, Post Office Royal Melbourne Hospital, Victoria 3050, Australia.

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https://academic.oup.com/mend/article-lookup/doi/10.1210/me.
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http://dx.doi.org/10.1210/me.2002-0108DOI Listing
September 2002