Publications by authors named "Karsten Suhre"

100Publications

Robust Huber-LASSO for improved prediction of protein, metabolite and gene expression levels relying on individual genotype data.

Brief Bioinform 2020 Oct 16. Epub 2020 Oct 16.

Statistical Genetics Research Group at the Institute of Medical Biometry and Informatics, Heidelberg University, Germany.

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http://dx.doi.org/10.1093/bib/bbaa230DOI Listing
October 2020

Genetics meets proteomics: perspectives for large population-based studies.

Nat Rev Genet 2020 Aug 28. Epub 2020 Aug 28.

Affinity Proteomics, Science for Life Laboratory, KTH Royal Institute of Technology, Stockholm, Sweden.

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http://dx.doi.org/10.1038/s41576-020-0268-2DOI Listing
August 2020

Identification of genetic variants controlling RNA editing and their effect on RNA structure stabilization.

Eur J Hum Genet 2020 Jul 10. Epub 2020 Jul 10.

Department of Physiology and Biophysics, Weill Cornell Medicine-Qatar, Education City, Doha, Qatar.

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http://dx.doi.org/10.1038/s41431-020-0688-7DOI Listing
July 2020

Proteome-wide assessment of diabetes mellitus in Qatari identifies IGFBP-2 as a risk factor already with early glycaemic disturbances.

Arch Biochem Biophys 2020 08 22;689:108476. Epub 2020 Jun 22.

Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, the Netherlands; Department of Public Health and Primary Care, Leiden University Medical Center, Leiden, the Netherlands.

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http://dx.doi.org/10.1016/j.abb.2020.108476DOI Listing
August 2020

Deletion of beta-fructofuranosidase (invertase) genes is associated with sucrose content in Date Palm fruit.

Plant Direct 2020 May 27;4(5):e00214. Epub 2020 May 27.

Department of Genetic Medicine Weill Cornell Medicine in Qatar Doha Qatar.

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http://dx.doi.org/10.1002/pld3.214DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7251787PMC
May 2020

Metabolomic profiling identifies novel associations with Electrolyte and Acid-Base Homeostatic patterns.

Sci Rep 2019 10 21;9(1):15088. Epub 2019 Oct 21.

Institute of Cardiovascular and Medical Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, UK.

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http://dx.doi.org/10.1038/s41598-019-51492-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6803625PMC
October 2019

Alterations in long noncoding RNAs in women with and without polycystic ovarian syndrome.

Clin Endocrinol (Oxf) 2019 12 1;91(6):793-797. Epub 2019 Oct 1.

Weill Cornell Medicine-Qatar, Education City, Doha, Qatar.

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http://dx.doi.org/10.1111/cen.14087DOI Listing
December 2019

Fine-Mapping of the Human Blood Plasma N-Glycome onto Its Proteome.

Metabolites 2019 Jun 26;9(7). Epub 2019 Jun 26.

Department of Twin Research and Genetic Epidemiology, King's College London, SE1 7EHLondon, UK.

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http://dx.doi.org/10.3390/metabo9070122DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6681129PMC
June 2019

Characterization of Bulk Phosphatidylcholine Compositions in Human Plasma Using Side-Chain Resolving Lipidomics.

Metabolites 2019 Jun 8;9(6). Epub 2019 Jun 8.

Institute of Bioinformatics and Systems Biology, Helmholtz Zentrum München-German Research Center for Environmental Health, 85764 Neuherberg, Germany.

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http://dx.doi.org/10.3390/metabo9060109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6631474PMC
June 2019

Metabolomics Identifies Novel Blood Biomarkers of Pulmonary Function and COPD in the General Population.

Metabolites 2019 Apr 1;9(4). Epub 2019 Apr 1.

Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, NC 27709, USA.

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http://dx.doi.org/10.3390/metabo9040061DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6523962PMC
April 2019

Metabolic and proteomic signatures of hypoglycaemia in type 2 diabetes.

Diabetes Obes Metab 2019 04 27;21(4):909-919. Epub 2018 Dec 27.

Department of Physiology and Biophysics, Weill Cornell Medicine Qatar, Education City, Doha, Qatar.

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http://dx.doi.org/10.1111/dom.13602DOI Listing
April 2019

ProGeM: a framework for the prioritization of candidate causal genes at molecular quantitative trait loci.

Nucleic Acids Res 2019 01;47(1):e3

MRC/BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge CB1 8RN, UK.

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http://dx.doi.org/10.1093/nar/gky837DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326795PMC
January 2019

MoDentify: phenotype-driven module identification in metabolomics networks at different resolutions.

Bioinformatics 2019 02;35(3):532-534

Institute of Computational Biology, Helmholtz Zentrum München, Neuherberg, Germany.

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http://dx.doi.org/10.1093/bioinformatics/bty650DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6361241PMC
February 2019

A comprehensive metabolomic data set of date palm fruit.

Data Brief 2018 Jun 10;18:1313-1321. Epub 2018 Apr 10.

Department of Physiology and Biophysics, Weill Cornell Medicine-Qatar, Education City, P.O. Box 24144, Doha, Qatar.

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https://linkinghub.elsevier.com/retrieve/pii/S23523409183036
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http://dx.doi.org/10.1016/j.dib.2018.04.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5997577PMC
June 2018

Single nucleotide variant counts computed from RNA sequencing and cellular traffic into human kidney allografts.

Am J Transplant 2018 10 15;18(10):2429-2442. Epub 2018 May 15.

Division of Nephrology and Hypertension, Department of Medicine, Weill Cornell Medical College, New York, New York.

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http://dx.doi.org/10.1111/ajt.14870DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6160347PMC
October 2018

From Discovery to Translation: Characterization of C-Mannosyltryptophan and Pseudouridine as Markers of Kidney Function.

Sci Rep 2017 12 12;7(1):17400. Epub 2017 Dec 12.

Institute of Genetic Epidemiology, Faculty of Medicine and Medical Center - University of Freiburg, Hugstetter Str. 49, 79106, Freiburg, Germany.

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http://dx.doi.org/10.1038/s41598-017-17107-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5727198PMC
December 2017

Advanced glycation end products among patients maintained on antipsychotics.

Int Clin Psychopharmacol 2017 09;32(5):256-261

Departments of aResearch bHealth Policy and Research cPhysiology and Biophysics dPsychiatry, Weill Cornell Medicine - Qatar eDepartment of Psychiatry, Rumailah Hospital, Hamad Medical Corporation fPrimary Healthcare Corporation, Doha, Qatar.

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http://dx.doi.org/10.1097/YIC.0000000000000179DOI Listing
September 2017

PopPAnTe: population and pedigree association testing for quantitative data.

BMC Genomics 2017 02 10;18(1):150. Epub 2017 Feb 10.

Department of Twin Research and Genetic Epidemiology, King's College London, London, UK.

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http://dx.doi.org/10.1186/s12864-017-3527-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5303218PMC
February 2017

Nesting of colon and ovarian cancer cells in the endothelial niche is associated with alterations in glycan and lipid metabolism.

Sci Rep 2017 01 4;7:39999. Epub 2017 Jan 4.

Stem Cell and Microenvironment Laboratory, Weill Cornell Medicine-Qatar, Education City, Qatar Foundation, Doha, Qatar.

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http://dx.doi.org/10.1038/srep39999DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5209689PMC
January 2017

Mendelian inheritance of trimodal CpG methylation sites suggests distal cis-acting genetic effects.

Clin Epigenetics 2016 22;8:124. Epub 2016 Nov 22.

Department of Physiology and Biophysics, Weill Cornell Medical College in Qatar, Education City, PO Box 24144, Doha, Qatar.

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http://dx.doi.org/10.1186/s13148-016-0295-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5120560PMC
April 2017

Metabolic Fingerprints of Circulating IGF-1 and the IGF-1/IGFBP-3 Ratio: A Multifluid Metabolomics Study.

J Clin Endocrinol Metab 2016 12 6;101(12):4730-4742. Epub 2016 Oct 6.

Institute of Clinical Chemistry and Laboratory Medicine (H.K., M.P., H.W., M.N., N.F.) and Institute for Community Medicine (H.V.), University Medicine Greifswald, Interfaculty Institute for Genetics and Functional Genomics (U.V.), University Medicine and Ernst-Moritz Arndt-University Greifswald, and German Center for Cardiovascular Research (M.N., N.F.), partner site Greifswald, 17475 Greifswald, Germany; Institute of Computational Biology (K.T.D., J.K., K.S.), Helmholtz-Zentrum München, and German Center for Diabetes Research (J.K.), and Institute of Bioinformatics and Systems Biology (W.R.-M., G.K.), Helmholtz Zentrum München, German Research Center for Environmental Health, and Institute of Experimental Genetics (A.A., J.A.), Genome Analysis Center, Helmholtz Zentrum München, Neuherberg, Germany, and German Center for Diabetes Research (J.A.), 85764 München-Neuherberg, Germany; Schwerpunktpraxis für Diabetes und Hormonerkrankungen (H.W.), 99094 Erfurt, Germany; Weill Cornell Medical College in Qatar (K.S.), Education City, Qatar Foundation, Doha, Qatar; Lehrstuhl für Experimentelle Genetik (J.A.), Technische Universität München, 85350 Freising-Weihenstephan, Germany; Research Centre for Prevention and Health (N.F.), Capital Region of Denmark, 2600 Glostrup, Denmark.

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http://dx.doi.org/10.1210/jc.2016-2588DOI Listing
December 2016

Metabolomics enables precision medicine: "A White Paper, Community Perspective".

Metabolomics 2016;12(10):149. Epub 2016 Sep 2.

Psychiatry and Behavioral Sciences, Duke Internal Medicine and Duke Institute for Brain Sciences and Center for Applied Genomics and Precision Medicine, Duke University Medical Center, Box 3903, Durham, NC 27710 USA.

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http://dx.doi.org/10.1007/s11306-016-1094-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5009152PMC
September 2016

Measurement of 1,5-anhydroglucitol in blood and saliva: from non-targeted metabolomics to biochemical assay.

J Transl Med 2016 05 18;14(1):140. Epub 2016 May 18.

Translational Research Institute, Academic Health System, Hamad Medical Corporation, PO Box 3050, Doha, Qatar.

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http://dx.doi.org/10.1186/s12967-016-0897-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4870767PMC
May 2016

Epigenetic associations of type 2 diabetes and BMI in an Arab population.

Clin Epigenetics 2016 28;8:13. Epub 2016 Jan 28.

Bioinformatics Core, Weill Cornell Medical College in Qatar, Qatar Foundation-Education City, PO Box 24144, Doha, Qatar.

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http://dx.doi.org/10.1186/s13148-016-0177-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4730771PMC
April 2016

Metabolomics of dates (Phoenix dactylifera) reveals a highly dynamic ripening process accounting for major variation in fruit composition.

BMC Plant Biol 2015 Dec 16;15:291. Epub 2015 Dec 16.

Department of Physiology and Biophysics, Weill Cornell Medical College, Qatar Foundation - Education City, PO Box 24144, Doha, Qatar.

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http://dx.doi.org/10.1186/s12870-015-0672-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4681049PMC
December 2015

Diagnostic and Prognostic Metabolites Identified for Joint Symptoms in the KORA Population.

J Proteome Res 2016 Feb 7;15(2):554-62. Epub 2016 Jan 7.

Department of Medicine, Weill Cornell Medical College - Qatar , Doha 24144, Qatar.

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http://dx.doi.org/10.1021/acs.jproteome.5b00951DOI Listing
February 2016

Response to Comment on Xu et al. Effects of Metformin on Metabolite Profiles and LDL Cholesterol in Patients With Type 2 Diabetes. Diabetes Care 2015;38:1858-1867.

Diabetes Care 2015 Dec;38(12):e216-7

Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, Neuherberg, Germany Institute of Epidemiology II, Helmholtz Zentrum München, Neuherberg, Germany German Center for Diabetes Research, Neuherberg, Germany

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http://dx.doi.org/10.2337/dci15-0022DOI Listing
December 2015

Guest Editorial: Special issue on metabolomics.

Arch Biochem Biophys 2016 Jan 20;589:1-3. Epub 2015 Oct 20.

Department of Biophysics and Physiology, Weill Cornell Medical College in Qatar, Doha, Qatar; Institute of Bioinformatics and Systems Biology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.abb.2015.10.013DOI Listing
January 2016

Gender-specific pathway differences in the human serum metabolome.

Metabolomics 2015;11(6):1815-1833. Epub 2015 Aug 4.

German Center for Diabetes Research (DZD e.V.), Neuherberg, Germany ; Institute of Bioinformatics and Systems Biology, Helmholtz Zentrum München, Neuherberg, Germany.

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http://dx.doi.org/10.1007/s11306-015-0829-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4605991PMC
August 2015

Associations of circulating plasma microRNAs with age, body mass index and sex in a population-based study.

BMC Med Genomics 2015 Oct 14;8:61. Epub 2015 Oct 14.

Department of Functional Genomics, Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald, , Friedrich-Ludwig-Jahn-Str. 15A, D-17475, Greifswald, Germany.

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http://dx.doi.org/10.1186/s12920-015-0136-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4604724PMC
October 2015

Biochemical insights from population studies with genetics and metabolomics.

Arch Biochem Biophys 2016 Jan 9;589:168-76. Epub 2015 Oct 9.

Institute of Bioinformatics and Systems Biology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; German Center for Diabetes Research, Neuherberg, Germany.

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http://dx.doi.org/10.1016/j.abb.2015.09.023DOI Listing
January 2016

Metabolic switch during adipogenesis: From branched chain amino acid catabolism to lipid synthesis.

Arch Biochem Biophys 2016 Jan 25;589:93-107. Epub 2015 Sep 25.

Institute of Experimental Genetics, Genome Analysis Center, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; German Center for Diabetes Research, Neuherberg, Germany; Lehrstuhl für Experimentelle Genetik, Technische Universität München, Freising-Weihenstephan, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.abb.2015.09.013DOI Listing
January 2016

MetaRNA-Seq: An Interactive Tool to Browse and Annotate Metadata from RNA-Seq Studies.

Biomed Res Int 2015 25;2015:318064. Epub 2015 Aug 25.

Weill Cornell Medical College in Qatar, Education City, Doha, Qatar ; Institute of Bioinformatics and System Biology, Helmholtz Zentrum Munchen, Germany Research Center of Environmental Health, 85764 Neuherberg, Germany.

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http://dx.doi.org/10.1155/2015/318064DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4561952PMC
June 2016

Type 2 diabetes is associated with postprandial amino acid measures.

Arch Biochem Biophys 2016 Jan 10;589:138-44. Epub 2015 Aug 10.

Department of Endocrinology, Leiden University Medical Center, Leiden, The Netherlands; Department of Human Genetics, Leiden University Medical Center, Leiden, The Netherlands.

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http://dx.doi.org/10.1016/j.abb.2015.08.003DOI Listing
January 2016

Metabolic signatures differentiate ovarian from colon cancer cell lines.

J Transl Med 2015 Jul 14;13:223. Epub 2015 Jul 14.

Stem Cell and Microenvironment Laboratory, Weill Cornell Medical College in Qatar, Education City, Qatar Foundation, Doha, Qatar.

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http://dx.doi.org/10.1186/s12967-015-0576-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4499939PMC
July 2015

Genetics of human metabolism: an update.

Hum Mol Genet 2015 Oct 9;24(R1):R93-R101. Epub 2015 Jul 9.

Institute of Bioinformatics and Systems Biology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany, Department of Physiology and Biophysics, Weill Cornell Medical College-Qatar, Doha, Qatar

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http://dx.doi.org/10.1093/hmg/ddv263DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4572003PMC
October 2015