Karsten Boldt

Karsten Boldt

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Karsten Boldt

Karsten Boldt

Publications by authors named "Karsten Boldt"

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CFAP43 modulates ciliary beating in mouse and Xenopus.

Dev Biol 2019 Dec 27. Epub 2019 Dec 27.

Institute for Molecular Biology, OE5250, Hannover Medical School, Carl-Neuberg-Str. 1, 30625, Hannover, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.ydbio.2019.12.010DOI Listing
December 2019

Affinity proteomics identifies novel functional modules related to adhesion GPCRs.

Ann N Y Acad Sci 2019 Nov 22;1456(1):144-167. Epub 2019 Aug 22.

Institute of Molecular Physiology, Molecular Cell Biology, Johannes Gutenberg University of Mainz, Mainz, Germany.

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http://dx.doi.org/10.1111/nyas.14220DOI Listing
November 2019

The small GTPase RAB28 is required for phagocytosis of cone outer segments by the murine retinal pigmented epithelium.

J Biol Chem 2018 11 18;293(45):17546-17558. Epub 2018 Sep 18.

From the Department of Ophthalmology and Visual Sciences, University of Utah Health Science Center, Salt Lake City, Utah 84132,

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http://dx.doi.org/10.1074/jbc.RA118.005484DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6231133PMC
November 2018

CRISPR/Cas9-mediated Genomic Editing of Cluap1/IFT38 Reveals a New Role in Actin Arrangement.

Mol Cell Proteomics 2018 07 3;17(7):1285-1294. Epub 2018 Apr 3.

From the ‡Institute for Ophthalmic Research, Centre for Ophthalmology, University of Tübingen, Elfriede-Aulhorn-Strasse 7, D-72076 Tübingen, Germany;

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http://dx.doi.org/10.1074/mcp.RA117.000487DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6030719PMC
July 2018

Liver cyst gene knockout in cholangiocytes inhibits cilium formation and Wnt signaling.

Hum Mol Genet 2017 11;26(21):4190-4202

Department of Human Genetics and Radboud Insitute for Molecular Life Sciences, Radboud University Medical Center, 6525 GA Nijmegen, The Netherlands.

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http://dx.doi.org/10.1093/hmg/ddx308DOI Listing
November 2017

1700012B09Rik, a FOXJ1 effector gene active in ciliated tissues of the mouse but not essential for motile ciliogenesis.

Dev Biol 2017 09 28;429(1):186-199. Epub 2017 Jun 28.

Institute for Molecular Biology, OE5250, Hannover Medical School, Carl-Neuberg-Str. 1, 30625 Hannover, Germany; REBIRTH Cluster of Excellence, Hannover, Germany.

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https://linkinghub.elsevier.com/retrieve/pii/S00121606163086
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http://dx.doi.org/10.1016/j.ydbio.2017.06.027DOI Listing
September 2017

Amplified pathogenic actions of angiotensin II in cysteine-rich LIM-only protein 4-negative mouse hearts.

FASEB J 2017 04 30;31(4):1620-1638. Epub 2017 Jan 30.

Department of Pharmacology, Toxicology, and Clinical Pharmacy, Institute of Pharmacy, University of Tübingen, Tübingen, Germany;

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http://dx.doi.org/10.1096/fj.201601186DOI Listing
April 2017

Autophosphorylation on S614 inhibits the activity and the transforming potential of BRAF.

Cell Signal 2016 09 21;28(9):1432-9. Epub 2016 Jun 21.

Medical Proteome Center, Division for Experimental Ophthalmology, Institute for Ophthalmic Research, University of Tuebingen, Tuebingen, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.cellsig.2016.06.016DOI Listing
September 2016

A subset of RAB proteins modulates PP2A phosphatase activity.

Sci Rep 2016 09 9;6:32857. Epub 2016 Sep 9.

Max Plank Institute for Biochemistry, Martinried, Munich (Germany).

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http://dx.doi.org/10.1038/srep32857DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5017145PMC
September 2016

HiQuant: Rapid Postquantification Analysis of Large-Scale MS-Generated Proteomics Data.

J Proteome Res 2016 06 16;15(6):2072-9. Epub 2016 May 16.

EMBL Australia Biomedical Informatics Group, Infection & Immunity Theme, South Australian Health and Medical Research Institute , North Terrace, Adelaide, South Australia 5000, Australia.

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http://dx.doi.org/10.1021/acs.jproteome.5b01008DOI Listing
June 2016

The Interaction of CCDC104/BARTL1 with Arl3 and Implications for Ciliary Function.

Structure 2015 Nov 9;23(11):2122-32. Epub 2015 Oct 9.

Max-Planck-Institute of Molecular Physiology, Emeritus Group, Otto-Hahn-Straße 15, 44227 Dortmund, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.str.2015.08.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4635315PMC
November 2015

The Ciliopathy Protein CC2D2A Associates with NINL and Functions in RAB8-MICAL3-Regulated Vesicle Trafficking.

PLoS Genet 2015 Oct 20;11(10):e1005575. Epub 2015 Oct 20.

Department of Otorhinolaryngology, Radboud University Medical Centre, Nijmegen, the Netherlands; Radboud Institute for Molecular Life Sciences, Radboud University Nijmegen, the Netherlands.

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http://dx.doi.org/10.1371/journal.pgen.1005575DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4617701PMC
October 2015

An siRNA-based functional genomics screen for the identification of regulators of ciliogenesis and ciliopathy genes.

Nat Cell Biol 2015 Aug 13;17(8):1074-1087. Epub 2015 Jul 13.

Section of Ophthalmology and Neuroscience, Leeds Institutes of Molecular Medicine, University of Leeds, Leeds, LS9 7TF, UK.

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http://www.nature.com/articles/ncb3201
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http://dx.doi.org/10.1038/ncb3201DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4536769PMC
August 2015

Expression of leukemia inhibitory factor in Müller glia cells is regulated by a redox-dependent mRNA stability mechanism.

BMC Biol 2015 Apr 25;13:30. Epub 2015 Apr 25.

Department of Ophthalmology, Lab for Retinal Cell Biology, University of Zurich, Wagistrasse 14, Zurich, 8091, Switzerland.

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http://dx.doi.org/10.1186/s12915-015-0137-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4462110PMC
April 2015

Applying SILAC for the differential analysis of protein complexes.

Methods Mol Biol 2014 ;1188:177-90

Division of Experimental Ophthalmology and Medical Proteome Center, Center of Ophthalmology, Institute for Ophthalmic Research, University of Tübingen, Roentgenweg 11, 72076, Tübingen, Germany,

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http://dx.doi.org/10.1007/978-1-4939-1142-4_13DOI Listing
March 2015

Elution profile analysis of SDS-induced subcomplexes by quantitative mass spectrometry.

Mol Cell Proteomics 2014 May 21;13(5):1382-91. Epub 2014 Feb 21.

Division of Experimental Ophthalmology and Medical Proteome Center, Centre for Ophthalmology, University of Tübingen, 72076 Tübingen, Germany;

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http://dx.doi.org/10.1074/mcp.O113.033233DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4014293PMC
May 2014

Combining affinity proteomics and network context to identify new phosphatase substrates and adapters in growth pathways.

Front Genet 2014 7;5:115. Epub 2014 May 7.

Department of Biology, University of Rome Tor Vergata Rome, Italy ; Istituto Ricovero e Cura a Carattere Scientifico, Fondazione Santa Lucia Rome, Italy.

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http://dx.doi.org/10.3389/fgene.2014.00115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4019850PMC
May 2014

Isotope coded protein labeling coupled immunoprecipitation (ICPL-IP): a novel approach for quantitative protein complex analysis from native tissue.

Mol Cell Proteomics 2013 May 26;12(5):1395-406. Epub 2012 Dec 26.

Institute for Ophthalmic Research, Division of Experimental Ophthalmology and Medical Proteome Center, University of Tuebingen, D-72076 Tuebingen, Germany.

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http://dx.doi.org/10.1074/mcp.O112.023648DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3650347PMC
May 2013

Proteomic analysis by SILAC and 2D-DIGE reveals radiation-induced endothelial response: four key pathways.

J Proteomics 2012 Apr 20;75(8):2319-30. Epub 2012 Feb 20.

Helmholtz Zentrum München, German Research Center for Environmental Health, Research Unit of Radiation Cytogenetics, Neuherberg, Germany.

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http://dx.doi.org/10.1016/j.jprot.2012.02.009DOI Listing
April 2012

A QUICK screen for Lrrk2 interaction partners--leucine-rich repeat kinase 2 is involved in actin cytoskeleton dynamics.

Mol Cell Proteomics 2011 Jan 27;10(1):M110.001172. Epub 2010 Sep 27.

Department of Protein Science, Helmholtz Zentrum München-German Research Center for Environmental Health (GmbH), 85764 Neuherberg, Germany.

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http://dx.doi.org/10.1074/mcp.M110.001172DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3013447PMC
January 2011

Tandem affinity purification of ciliopathy-associated protein complexes.

Methods Cell Biol 2009 1;91:143-60. Epub 2009 Dec 1.

Department of Protein Science, Helmholtz Zentrum München, 85764 Neuherberg, Germany.

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http://dx.doi.org/10.1016/S0091-679X(08)91009-8DOI Listing
July 2010

Phosphopeptide analysis reveals two discrete clusters of phosphorylation in the N-terminus and the Roc domain of the Parkinson-disease associated protein kinase LRRK2.

J Proteome Res 2010 Apr;9(4):1738-45

Helmholtz Zentrum München-German Research Center for Environmental Health, Department of Protein Science, Neuherberg, Germany.

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http://dx.doi.org/10.1021/pr9008578DOI Listing
April 2010

Tandem affinity purification of protein complexes from mammalian cells by the Strep/FLAG (SF)-TAP tag.

Methods Mol Biol 2009 ;564:359-72

Department of Protein Science, Helmholtz Zentrum München-German Research Center for Environmental Health, Ingolstaedter Landstrasse 1, 85764 Neuherberg, Germany.

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http://link.springer.com/content/pdf/10.1007/978-1-60761-157
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http://link.springer.com/10.1007/978-1-60761-157-8_21
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http://dx.doi.org/10.1007/978-1-60761-157-8_21DOI Listing
October 2009

Strep/FLAG tandem affinity purification (SF-TAP) to study protein interactions.

Curr Protoc Protein Sci 2009 Aug;Chapter 19:Unit19.20

Helmholtz Zentrum München, Neuherberg, Germany.

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http://dx.doi.org/10.1002/0471140864.ps1920s57DOI Listing
August 2009

The Parkinson disease-associated protein kinase LRRK2 exhibits MAPKKK activity and phosphorylates MKK3/6 and MKK4/7, in vitro.

J Neurochem 2009 May 3;109(4):959-68. Epub 2009 Mar 3.

Department of Protein Science, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.

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http://dx.doi.org/10.1111/j.1471-4159.2009.06024.xDOI Listing
May 2009

Identification of paracrine neuroprotective candidate proteins by a functional assay-driven proteomics approach.

Mol Cell Proteomics 2008 Jul 23;7(7):1349-61. Epub 2008 Apr 23.

Institute of Human Genetics, Helmholtz Zentrum Muenchen-German Research Center for Environmental Health (GmbH), 85764 Neuherberg, Germany.

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http://www.mcponline.org/lookup/doi/10.1074/mcp.M700456-MCP2
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http://dx.doi.org/10.1074/mcp.M700456-MCP200DOI Listing
July 2008

A novel tandem affinity purification strategy for the efficient isolation and characterisation of native protein complexes.

Proteomics 2007 Dec;7(23):4228-34

Institute of Human Genetics, GSF-National Research Center for Environment and Health, Neuherberg, Germany.

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http://dx.doi.org/10.1002/pmic.200700038DOI Listing
December 2007

FPRL-1 induces modifications of migration-associated proteins in human neutrophils.

Proteomics 2006 Sep;6(17):4790-9

Boehringer Ingelheim Pharma GmbH & Co. KG, Department of Respiratory Research, Genomics Group, Biberach an der Riss, Germany.

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http://dx.doi.org/10.1002/pmic.200600121DOI Listing
September 2006