Publications by authors named "Karoline Gleixner"

50Publications

Hereditary alpha tryptasemia is a valid genetic biomarker for severe mediator-related symptoms in mastocytosis.

Authors:
Georg Greiner Bettina Sprinzl Aleksandra Górska Franz Ratzinger Michael Gurbisz Nadine Witzeneder Klaus G Schmetterer Bettina Gisslinger Goekhan Uyanik Emir Hadzijusufovic Harald Esterbauer Karoline Veronika Gleixner Maria Theresa Krauth Michael Pfeilstöcker Felix Keil Heinz Gisslinger Boguslaw Nedoszytko Marek Niedoszytko Wolfgang R Sperr Peter Valent Gregor Hoermann

Blood 2020 Aug 10. Epub 2020 Aug 10.

MLL Munich Leukemia Laboratory, Germany.

View Article and Find Full Text PDF
August 2020

Emicizumab for the treatment of acquired hemophilia A.

Authors:
Paul Knoebl Johannes Thaler Petra Jilma Peter Quehenberger Karoline Veronika Gleixner Wolfgang R Sperr

Blood 2020 Aug 7. Epub 2020 Aug 7.

Dept. of. Int.Med.I, Div.of Hematology, Vienna, Austria.

View Article and Find Full Text PDF
August 2020

Clinical features and survival of patients with indolent systemic mastocytosis defined by the updated WHO classification.

Authors:
Jakub Trizuljak Wolfgang R Sperr Lucie Nekvindová Hanneke O Elberink Karoline V Gleixner Aleksandra Gorska Magdalena Lange Karin Hartmann Anja Illerhaus Massimiliano Bonifacio Cecelia Perkins Chiara Elena Luca Malcovati Anna B Fortina Khalid Shoumariyeh Mohamad Jawhar Roberta Zanotti Patrizia Bonadonna Francesca Caroppo Alexander Zink Massimo Triggiani Roberta Parente Nikolas von Bubnoff Akif S Yavuz Hans Hägglund Mattias Mattsson Jens Panse Nadja Jäkel Alex Kilbertus Olivier Hermine Michel Arock David Fuchs Vito Sabato Knut Brockow Agnes Bretterklieber Marek Niedoszytko Björn van Anrooij Andreas Reiter Jason Gotlib Hanneke C Kluin-Nelemans Jiri Mayer Michael Doubek Peter Valent

Allergy 2020 08 16;75(8):1927-1938. Epub 2020 Mar 16.

Department of Internal Medicine I, Division of Hematology and Hemostaseology, Ludwig Boltzmann Institute for Hematology and Oncology, Medical University of Vienna, Vienna, Austria.

View Article and Find Full Text PDF
August 2020

CDK4/CDK6 inhibition as a novel strategy to suppress the growth and survival of BCR-ABL1+ clones in TKI-resistant CML.

Authors:
Mathias Schneeweiss-Gleixner Konstantin Byrgazov Gabriele Stefanzl Daniela Berger Gregor Eisenwort Chantal Blanche Lucini Susanne Herndlhofer Sandra Preuner Klara Obrova Petra Pusic Nadine Witzeneder Georg Greiner Gregor Hoermann Wolfgang R Sperr Thomas Lion Michael Deininger Peter Valent Karoline V Gleixner

EBioMedicine 2019 Dec 21;50:111-121. Epub 2019 Nov 21.

Department of Internal Medicine I, Division of Hematology & Hemostaseology, Medical University of Vienna, Waehringer Guertel 18-20, 1090 Vienna, Austria; Ludwig Boltzmann Institute for Hematology & Oncology, Medical University of Vienna, Austria. Electronic address:

View Article and Find Full Text PDF
December 2019

International prognostic scoring system for mastocytosis (IPSM): a retrospective cohort study.

Authors:
Wolfgang R Sperr Michael Kundi Ivan Alvarez-Twose Bjorn van Anrooij Joanna N G Oude Elberink Aleksandra Gorska Marek Niedoszytko Karoline V Gleixner Emir Hadzijusufovic Roberta Zanotti Patrizia Bonadonna Massimiliano Bonifacio Cecelia Perkins Anja Illerhaus Chiara Elena Serena Merante Khalid Shoumariyeh Nikolas von Bubnoff Roberta Parente Mohamad Jawhar Anna Belloni Fortina Francesca Caroppo Knut Brockow Alexander Zink David Fuchs Alex J Kilbertus Akif Selim Yavuz Michael Doubek Hans Hägglund Jens Panse Vito Sabato Agnes Bretterklieber Dietger Niederwieser Christine Breynaert Karin Hartmann Massimo Triggiani Boguslaw Nedoszytko Andreas Reiter Alberto Orfao Olivier Hermine Jason Gotlib Michel Arock Hanneke C Kluin-Nelemans Peter Valent

Lancet Haematol 2019 Dec 31;6(12):e638-e649. Epub 2019 Oct 31.

Department of Internal Medicine I, Division of Hematology and Hemostaseology, and Ludwig Boltzmann Institute for Hematology and Oncology, Medical University of Vienna, Vienna, Austria.

View Article and Find Full Text PDF
December 2019

Immunotherapy-Based Targeting and Elimination of Leukemic Stem Cells in AML and CML.

Authors:
Peter Valent Irina Sadovnik Gregor Eisenwort Karin Bauer Harald Herrmann Karoline V Gleixner Axel Schulenburg Werner Rabitsch Wolfgang R Sperr Dominik Wolf

Int J Mol Sci 2019 Aug 29;20(17). Epub 2019 Aug 29.

Department of Internal Medicine V (Hematology & Oncology), Medical University of Innsbruck, 1090 Innsbruck, Austria.

View Article and Find Full Text PDF
August 2019

Multidisciplinary Challenges in Mastocytosis and How to Address with Personalized Medicine Approaches.

Authors:
Peter Valent Cem Akin Karoline V Gleixner Wolfgang R Sperr Andreas Reiter Michel Arock Massimo Triggiani

Int J Mol Sci 2019 Jun 18;20(12). Epub 2019 Jun 18.

Division of Allergy and Clinical Immunology, University of Salerno, 84131 Salerno, Italy.

View Article and Find Full Text PDF
June 2019

A kinase profile-adapted drug combination elicits synergistic cooperative effects on leukemic cells carrying BCR-ABL1 in Ph+ CML.

Authors:
Karoline V Gleixner Irina Sadovnik Mathias Schneeweiss Gregor Eisenwort Konstantin Byrgazov Gabriele Stefanzl Daniela Berger Harald Herrmann Emir Hadzijusufovic Thomas Lion Peter Valent

Leuk Res 2019 03 28;78:36-44. Epub 2018 Dec 28.

Department of Internal Medicine I, Division of Hematology & Hemostaseology, Medical University of Vienna, Austria; Ludwig Boltzmann Institute for Hematology and Oncology, Medical University of Vienna, Austria. Electronic address:

View Article and Find Full Text PDF
March 2019

The Data Registry of the European Competence Network on Mastocytosis (ECNM): Set Up, Projects, and Perspectives.

Authors:
Peter Valent Joanna N G Oude Elberink Aleksandra Gorska Magdalena Lange Roberta Zanotti Björn van Anrooij Massimiliano Bonifacio Patrizia Bonadonna Karoline V Gleixner Emir Hadzijusufovic Cecelia Perkins Karin Hartmann Anja Illerhaus Serena Merante Chiara Elena Khalid Shoumariyeh Nikolas von Bubnoff Roberta Parente Massimo Triggiani Juliana Schwaab Mohamad Jawhar Francesca Caroppo Anna Belloni Fortina Knut Brockow David Fuchs Rosemarie Greul Akif Selim Yavuz Michael Doubek Mattias Mattsson Hans Hagglund Jens Panse Vito Sabato Elisabeth Aberer Haifa Kathrin Al-Ali Marie-Anne Morren Judit Varkonyi Alexander Zink Marek Niedoszytko Dietger Niederwieser Luca Malcovati Andreas Reiter Vanessa Kennedy Jason Gotlib Olivier Lortholary Olivier Hermine Michel Arock Hanneke Kluin-Nelemans Wolfgang R Sperr

J Allergy Clin Immunol Pract 2019 01 8;7(1):81-87. Epub 2018 Nov 8.

Department of Internal Medicine I, Division of Hematology and Hemostaseology, Medical University of Vienna, Vienna, Austria; Ludwig Boltzmann Institute for Hematology & Oncology, Medical University of Vienna, Vienna, Austria.

View Article and Find Full Text PDF
January 2019

Ludwig Boltzmann Cluster Oncology (LBC ONC): first 10 years and future perspectives.

Authors:
Peter Valent Emir Hadzijusufovic Thomas Grunt Heidrun Karlic Barbara Peter Harald Herrmann Gregor Eisenwort Gregor Hoermann Axel Schulenburg Michael Willmann Rainer Hubmann Medhat Shehata Edgar Selzer Karoline V Gleixner Thomas Rülicke Wolfgang R Sperr Brigitte Marian Michael Pfeilstöcker Hubert Pehamberger Felix Keil Ulrich Jäger Christoph Zielinski

Wien Klin Wochenschr 2018 Sep 13;130(17-18):517-529. Epub 2018 Jul 13.

Ludwig Boltzmann Cluster Oncology, Vienna, Austria.

View Article and Find Full Text PDF
September 2018

Preclinical human models and emerging therapeutics for advanced systemic mastocytosis.

Authors:
Michel Arock Ghaith Wedeh Gregor Hoermann Siham Bibi Cem Akin Barbara Peter Karoline V Gleixner Karin Hartmann Joseph H Butterfield Dean D Metcalfe Peter Valent

Haematologica 2018 11 5;103(11):1760-1771. Epub 2018 Jul 5.

Ludwig Boltzmann Cluster Oncology, Medical University of Vienna, Austria.

View Article and Find Full Text PDF
November 2018

Major response of PNH to an AML chemotherapy protocol.

Authors:
Wolfgang Füreder Wolfgang R Sperr Karoline Gleixner Renate Thalhammer Ilse Schwarzinger Gregor Hoermann Christoph Kornauth Birgit Grünberger Peter Valent

Ann Hematol 2018 Aug 22;97(8):1487-1488. Epub 2018 Mar 22.

Department of Internal Medicine I, Division of Hematology and Hemostaseology, Medical University of Vienna, Währinger Gürtel 18-20, 1090, Vienna, Austria.

View Article and Find Full Text PDF
August 2018

The KIT and PDGFRA switch-control inhibitor DCC-2618 blocks growth and survival of multiple neoplastic cell types in advanced mastocytosis.

Authors:
Mathias Schneeweiss Barbara Peter Siham Bibi Gregor Eisenwort Dubravka Smiljkovic Katharina Blatt Mohamad Jawhar Daniela Berger Gabriele Stefanzl Susanne Herndlhofer Georg Greiner Gregor Hoermann Emir Hadzijusufovic Karoline V Gleixner Peter Bettelheim Klaus Geissler Wolfgang R Sperr Andreas Reiter Michel Arock Peter Valent

Haematologica 2018 05 8;103(5):799-809. Epub 2018 Feb 8.

Ludwig Boltzmann Cluster Oncology, Medical University of Vienna, Austria

View Article and Find Full Text PDF
May 2018

Intensive consolidation with G-CSF support: Tolerability, safety, reduced hospitalization, and efficacy in acute myeloid leukemia patients ≥60 years.

Authors:
Wolfgang R Sperr Susanne Herndlhofer Karoline Gleixner Michael Girschikofsky Ansgar Weltermann Sigrid Machherndl-Spandl Thamer Sliwa Rainer Poehnl Veronika Buxhofer-Ausch Karin Strecker Gregor Hoermann Paul Knoebl Ulrich Jaeger Klaus Geissler Michael Kundi Peter Valent

Am J Hematol 2017 Oct 17;92(10):E567-E574. Epub 2017 Aug 17.

Department of Internal Medicine I, Division of Hematology and Hemostaseology, Medical University of Vienna, Wien, Austria.

View Article and Find Full Text PDF
October 2017

Combined targeting of STAT3 and STAT5: a novel approach to overcome drug resistance in chronic myeloid leukemia.

Authors:
Karoline V Gleixner Mathias Schneeweiss Gregor Eisenwort Daniela Berger Harald Herrmann Katharina Blatt Georg Greiner Konstantin Byrgazov Gregor Hoermann Marina Konopleva Islam Waliul Abbarna A Cumaraswamy Patrick T Gunning Hiroshi Maeda Richard Moriggl Michael Deininger Thomas Lion Michael Andreeff Peter Valent

Haematologica 2017 09 8;102(9):1519-1529. Epub 2017 Jun 8.

Department of Internal Medicine I, Division of Hematology and Hemostaseology, Medical University of Vienna, Austria.

View Article and Find Full Text PDF
September 2017

TKI rotation-induced persistent deep molecular response in multi-resistant blast crisis of Ph+ CML.

Authors:
Peter Valent Susanne Herndlhofer Mathias Schneeweiß Bernd Boidol Anna Ringler Stefan Kubicek Karoline V Gleixner Gregor Hoermann Emir Hadzijusufovic Leonhard Müllauer Wolfgang R Sperr Giulio Superti-Furga Christine Mannhalter

Oncotarget 2017 Apr;8(14):23061-23072

Department of Laboratory Medicine, Medical University of Vienna, Austria.

View Article and Find Full Text PDF
April 2017

Plerixafor as preemptive strategy results in high success rates in autologous stem cell mobilization failure.

Authors:
Nina Worel Gerhard Fritsch Hermine Agis Alexandra Böhm Georg Engelich Gerda C Leitner Klaus Geissler Karoline Gleixner Peter Kalhs Veronika Buxhofer-Ausch Felix Keil Gerhard Kopetzky Viktor Mayr Werner Rabitsch Regina Reisner Konrad Rosskopf Reinhard Ruckser Claudia Zoghlami Niklas Zojer Hildegard T Greinix

J Clin Apher 2017 Aug 31;32(4):224-234. Epub 2016 Aug 31.

Division of Haematology, Medical University of Graz, Austria.

View Article and Find Full Text PDF
August 2017

Maintenance therapy with histamine plus IL-2 induces a striking expansion of two CD56bright NK cell subpopulations in patients with acute myeloid leukemia and supports their activation.

Authors:
Angélica Cuapio Mirte Post Sabine Cerny-Reiterer Karoline V Gleixner Gabriele Stefanzl Jose Basilio Susanne Herndlhofer Wolfgang R Sperr Nicolaas H C Brons Emilio Casanova Jacques Zimmer Peter Valent Erhard Hofer

Oncotarget 2016 Jul;7(29):46466-46481

Department of Vascular Biology and Thrombosis Research, Medical University of Vienna, Vienna, Austria.

View Article and Find Full Text PDF
July 2016

CD52 is a molecular target in advanced systemic mastocytosis.

Authors:
Gregor Hoermann Katharina Blatt Georg Greiner Eva Maria Putz Angelika Berger Harald Herrmann Sabine Cerny-Reiterer Karoline V Gleixner Christoph Walz Konrad Hoetzenecker Leonhard Müllauer Andreas Reiter Karl Sotlar Veronika Sexl Peter Valent Matthias Mayerhofer

FASEB J 2014 Aug 23;28(8):3540-51. Epub 2014 Apr 23.

Ludwig Boltzmann Institute of Osteology, Hanusch Hospital, Vienna, Austria

View Article and Find Full Text PDF
August 2014

Identification of heat shock protein 32 (Hsp32) as a novel target in acute lymphoblastic leukemia.

Authors:
Sabine Cerny-Reiterer Renata A Meyer Harald Herrmann Barbara Peter Karoline V Gleixner Gabriele Stefanzl Emir Hadzijusufovic Winfried F Pickl Wolfgang R Sperr Junia V Melo Hiroshi Maeda Ulrich Jäger Peter Valent

Oncotarget 2014 Mar;5(5):1198-211

Ludwig Boltzmann Cluster Oncology, Medical University of Vienna, Austria.

View Article and Find Full Text PDF
March 2014