Dr. Karl-Heinz Smalla, PhD - Leibniz-Institute for Neurobiology

Dr. Karl-Heinz Smalla

PhD

Leibniz-Institute for Neurobiology

Magdeburg | Germany

Main Specialties: Biology

Additional Specialties: synapse protein biochemistry, proteomics, subcellular fractionations

ORCID logohttps://orcid.org/0000-0002-0269-0311


Top Author

Dr. Karl-Heinz Smalla, PhD - Leibniz-Institute for Neurobiology

Dr. Karl-Heinz Smalla

PhD

Introduction

1. Koopmans, F., et al., SynGO: An Evidence-Based, Expert-Curated Knowledge Base for the Synapse. Neuron, 2019.
2. Gomez-Molina, C., et al., Small Extracellular Vesicles in Rat Serum Contain Astrocyte-Derived Protein Biomarkers of Repetitive Stress. Int J Neuropsychopharmacol, 2019. 22(3): p. 232-246.
3. Lang, D., et al., Chronic Toxoplasma infection is associated with distinct alterations in the synaptic protein composition. J Neuroinflammation, 2018. 15(1): p. 216.
4. Leutritz, T., et al., Contribution of iron and protein contents from rat brain subcellular fractions to MR phase imaging. Magn Reson Med, 2017. 77(5): p. 2028-2039.
5. Korthals, M., et al., A complex of Neuroplastin and Plasma Membrane Ca(2+) ATPase controls T cell activation. Sci Rep, 2017. 7(1): p. 8358.
6. Herrera-Molina, R., et al., Neuroplastin deletion in glutamatergic neurons impairs selective brain functions and calcium regulation: implication for cognitive deterioration. Sci Rep, 2017. 7(1): p. 7273.
7. Fernandez-Orth, J., et al., 14-3-3 Proteins regulate K2P 5.1 surface expression on T lymphocytes. Traffic, 2017. 18(1): p. 29-43.
8. Bhattacharya, S., et al., Genetically Induced Retrograde Amnesia of Associative Memories After Neuroplastin Ablation. Biol Psychiatry, 2017. 81(2): p. 124-135.
9. Kolodziej, A., et al., High Resolution Quantitative Synaptic Proteome Profiling of Mouse Brain Regions After Auditory Discrimination Learning. J Vis Exp, 2016(118).
10. Kahne, T., et al., Proteome rearrangements after auditory learning: high-resolution profiling of synapse-enriched protein fractions from mouse brain. J Neurochem, 2016. 138(1): p. 124-38.
11. Reichenbach, N., et al., Differential effects of dopamine signalling on long-term memory formation and consolidation in rodent brain. Proteome Sci, 2015. 13: p. 13.
12. Seidensticker, M., et al., Tumor cell uptake of 99mTc-labeled 1-thio-beta-D-glucose and 5-thio-D-glucose in comparison with 2-deoxy-2-[18F]fluoro-D-glucose in vitro: kinetics, dependencies, blockage and cell compartment of accumulation. Mol Imaging Biol, 2014. 16(2): p. 189-98.
13. Herrera-Molina, R., et al., Structure of excitatory synapses and GABAA receptor localization at inhibitory synapses are regulated by neuroplastin-65. J Biol Chem, 2014. 289(13): p. 8973-88.
14. Beesley, P.W., et al., The Neuroplastin adhesion molecules: key regulators of neuronal plasticity and synaptic function. J Neurochem, 2014. 131(3): p. 268-83.
15. Sandoval, M., et al., The glycolytic enzyme aldolase C is up-regulated in rat forebrain microsomes and in the cerebrospinal fluid after repetitive fluoxetine treatment. Brain Res, 2013. 1520: p. 1-14.
16. Li, L., et al., Distinct set of kinases induced after retrieval of spatial memory discriminate memory modulation processes in the mouse hippocampus. Hippocampus, 2013.
17. Leutritz, T., et al., Accurate quantification of water-macromolecule exchange induced frequency shift: effects of reference substance. Magn Reson Med, 2013. 69(1): p. 263-8.
18. Schmeisser, M.J., et al., Autistic-like behaviours and hyperactivity in mice lacking ProSAP1/Shank2. Nature, 2012. 486(7402): p. 256-60.
19. Schicknick, H., et al., Dopamine modulates memory consolidation of discrimination learning in the auditory cortex. Eur J Neurosci, 2012. 35(5): p. 763-74.
20. Sarto-Jackson, I., et al., The cell adhesion molecule neuroplastin-65 is a novel interaction partner of gamma-aminobutyric acid type A receptors. J Biol Chem, 2012. 287(17): p. 14201-14.
21. Pielot, R., et al., SynProt: A Database for Proteins of Detergent-Resistant Synaptic Protein Preparations. Front Synaptic Neurosci, 2012. 4: p. 1.
22. Mlinac, K., et al., Neuroplastin expression in the hippocampus of mice lacking complex gangliosides. J Mol Neurosci, 2012. 48(1): p. 161-6.
23. Kahne, T., et al., Synaptic proteome changes in mouse brain regions upon auditory discrimination learning. Proteomics, 2012. 12(15-16): p. 2433-44.
24. Bernstein, H.G., et al., Increased density of prohibitin-immunoreactive oligodendrocytes in the dorsolateral prefrontal white matter of subjects with schizophrenia suggests extraneuronal roles for the protein in the disease. Neuromolecular Med, 2012. 14(4): p. 270-80.
25. Sandoval, R., et al., Homeostatic NMDA receptor down-regulation via brain derived neurotrophic factor and nitric oxide-dependent signalling in cortical but not in hippocampal neurons. J Neurochem, 2011. 118(5): p. 760-72.
26. Goswami, C., et al., TRPV1 acts as a synaptic protein and regulates vesicle recycling. J Cell Sci, 2010. 123(Pt 12): p. 2045-57.
27. Smalla, K.H., et al., Altered postsynaptic-density-levels of caldendrin in the para-chloroamphetamine-induced serotonin syndrome but not in the rat ketamine model of psychosis. Neurochem Res, 2009. 34(8): p. 1405-9.
28. Mikhaylova, M., et al., Calneurons provide a calcium threshold for trans-Golgi network to plasma membrane trafficking. Proc Natl Acad Sci U S A, 2009. 106(22): p. 9093-8.
29. Juch, M., et al., Congenital lack of nNOS impairs long-term social recognition memory and alters the olfactory bulb proteome. Neurobiol Learn Mem, 2009. 92(4): p. 469-84.
30. Smalla, K.H., et al., A comparison of the synaptic proteome in human chronic schizophrenia and rat ketamine psychosis suggest that prohibitin is involved in the synaptic pathology of schizophrenia. Mol Psychiatry, 2008. 13(9): p. 878-96.
31. Schicknick, H., et al., Dopaminergic modulation of auditory cortex-dependent memory consolidation through mTOR. Cereb Cortex, 2008. 18(11): p. 2646-58.
32. Saavedra, M.V., et al., Scaffolding proteins in highly purified rat olfactory cilia membranes. Neuroreport, 2008. 19(11): p. 1123-6.
33. Dieterich, D.C., et al., Caldendrin-Jacob: a protein liaison that couples NMDA receptor signalling to the nucleus. PLoS Biol, 2008. 6(2): p. e34.
34. Sandoval, M., et al., Antagonistic effects of TrkB and p75(NTR) on NMDA receptor currents in post-synaptic densities transplanted into Xenopus oocytes. J Neurochem, 2007. 101(6): p. 1672-84.
35. Putzke, J., et al., The effects of p-chloroamphetamine, methamphetamine and 3,4-methylenedioxymethamphetamine (ecstasy) on the gene expression of cytoskeletal proteins in the rat brain. Addict Biol, 2007. 12(1): p. 69-80.
36. Langnaese, K., et al., Splice-isoform specific immunolocalization of neuronal nitric oxide synthase in mouse and rat brain reveals that the PDZ-complex-building nNOSalpha beta-finger is largely exposed to antibodies. Dev Neurobiol, 2007. 67(4): p. 422-37.
37. Bernstein, H.G., et al., The immunolocalization of the synaptic glycoprotein neuroplastin differs substantially between the human and the rodent brain. Brain Res, 2007. 1134(1): p. 107-12.
38. Bernstein, H.G., et al., A reduced number of cortical neurons show increased Caldendrin protein levels in chronic schizophrenia. Schizophr Res, 2007. 96(1-3): p. 246-56.
39. Wendholt, D., et al., ProSAP-interacting protein 1 (ProSAPiP1), a novel protein of the postsynaptic density that links the spine-associated Rap-Gap (SPAR) to the scaffolding protein ProSAP2/Shank3. J Biol Chem, 2006. 281(19): p. 13805-16.
40. Mikhaylova, M., et al., Neuronal Ca2+ signaling via caldendrin and calneurons. Biochim Biophys Acta, 2006. 1763(11): p. 1229-37.
41. John, N., et al., Brevican-containing perineuronal nets of extracellular matrix in dissociated hippocampal primary cultures. Mol Cell Neurosci, 2006. 31(4): p. 774-84.
42. Li, K., et al., Organelle proteomics of rat synaptic proteins: correlation-profiling by isotope-coded affinity tagging in conjunction with liquid chromatography-tandem mass spectrometry to reveal post-synaptic density specific proteins. J Proteome Res, 2005. 4(3): p. 725-33.
43. Seidenbecher, C.I., et al., Caldendrin but not calmodulin binds to light chain 3 of MAP1A/B: an association with the microtubule cytoskeleton highlighting exclusive binding partners for neuronal Ca(2+)-sensor proteins. J Mol Biol, 2004. 336(4): p. 957-70.
44. Roumier, A., et al., Impaired synaptic function in the microglial KARAP/DAP12-deficient mouse. J Neurosci, 2004. 24(50): p. 11421-8.
45. Li, K.W., et al., Proteomics analysis of rat brain postsynaptic density. Implications of the diverse protein functional groups for the integration of synaptic physiology. J Biol Chem, 2004. 279(2): p. 987-1002.
46. Smalla, K.H., et al., Kainate-induced epileptic seizures induce a recruitment of caldendrin to the postsynaptic density in rat brain. Brain Res Mol Brain Res, 2003. 116(1-2): p. 159-62.
47. Marzban, H., et al., Expression of the immunoglobulin superfamily neuroplastin adhesion molecules in adult and developing mouse cerebellum and their localisation to parasagittal stripes. J Comp Neurol, 2003. 462(3): p. 286-301.
48. Dieterich, D.C., et al., Gliap--a novel untypical L-asparaginase localized to rat brain astrocytes. J Neurochem, 2003. 85(5): p. 1117-25.
49. Bernstein, H.G., et al., Distribution and cellular localization of caldendrin immunoreactivity in adult human forebrain. J Histochem Cytochem, 2003. 51(8): p. 1109-12.
50. Seidenbecher, C.I., et al., Brevican isoforms associate with neural membranes. J Neurochem, 2002. 83(3): p. 738-46.
51. Laube, G., et al., The neuron-specific Ca2+-binding protein caldendrin: gene structure, splice isoforms, and expression in the rat central nervous system. Mol Cell Neurosci, 2002. 19(3): p. 459-75.
52. Chamaon, K., et al., Nicotinic acetylcholine receptors of Drosophila: three subunits encoded by genomically linked genes can co-assemble into the same receptor complex. J Neurochem, 2002. 80(1): p. 149-57.
53. Wyneken, U., et al., Kainate-induced seizures alter protein composition and N-methyl-D-aspartate receptor function of rat forebrain postsynaptic densities. Neuroscience, 2001. 102(1): p. 65-74.
54. Boeckers, T.M., et al., Proline-rich synapse-associated protein-1/cortactin binding protein 1 (ProSAP1/CortBP1) is a PDZ-domain protein highly enriched in the postsynaptic density. Ann Anat, 2001. 183(2): p. 101.
55. Spilker, C., et al., The neuronal EF-hand calcium-binding protein visinin-like protein-3 is expressed in cerebellar Purkinje cells and shows a calcium-dependent membrane association. Neuroscience, 2000. 96(1): p. 121-9.
56. Smalla, K.H., et al., The synaptic glycoprotein neuroplastin is involved in long-term potentiation at hippocampal CA1 synapses. Proc Natl Acad Sci U S A, 2000. 97(8): p. 4327-32.
57. Schulz, R., et al., Neuronal nicotinic acetylcholine receptors from Drosophila: two different types of alpha subunits coassemble within the same receptor complex. J Neurochem, 2000. 74(6): p. 2537-46.
58. Matthies, H., et al., Enhancement of glutamate release by L-fucose changes effects of glutamate receptor antagonists on long-term potentiation in the rat hippocampus. Learn Mem, 2000. 7(4): p. 227-34.
59. Keilhoff, G., et al., Neuroma: a donor-age independent source of human Schwann cells for tissue engineered nerve grafts. Neuroreport, 2000. 11(17): p. 3805-9.
60. Chamaon, K., et al., Neuronal nicotinic acetylcholine receptors of Drosophila melanogaster: the alpha-subunit dalpha3 and the beta-type subunit ARD co-assemble within the same receptor complex. FEBS Lett, 2000. 482(3): p. 189-92.
61. Matthies, H., Jr., et al., Glycosylation of proteins during a critical time window is necessary for the maintenance of long-term potentiation in the hippocampal CA1 region. Neuroscience, 1999. 91(1): p. 175-83.
62. Boeckers, T.M., et al., Proline-rich synapse-associated proteins ProSAP1 and ProSAP2 interact with synaptic proteins of the SAPAP/GKAP family. Biochem Biophys Res Commun, 1999. 264(1): p. 247-52.
63. Boeckers, T.M., et al., Proline-rich synapse-associated protein-1/cortactin binding protein 1 (ProSAP1/CortBP1) is a PDZ-domain protein highly enriched in the postsynaptic density. J Neurosci, 1999. 19(15): p. 6506-18.
64. tom Dieck, S., et al., Bassoon, a novel zinc-finger CAG/glutamine-repeat protein selectively localized at the active zone of presynaptic nerve terminals. J Cell Biol, 1998. 142(2): p. 499-509.
65. Smalla, K.H., et al., Identification of fucose alpha(1-2) galactose epitope-containing glycoproteins from rat hippocampus. Neuroreport, 1998. 9(5): p. 813-7.
66. Seidenbecher, C.I., et al., Caldendrin, a novel neuronal calcium-binding protein confined to the somato-dendritic compartment. J Biol Chem, 1998. 273(33): p. 21324-31.
67. Krug, M., et al., Fucose and fucose-containing sugar epitopes enhance hippocampal long-term potentiation in the freely moving rat. Brain Res, 1994. 643(1-2): p. 130-5.
68. Zuschratter, W., et al., Distribution of (fucogalactosyl-)epitope expressing glycoconjugates in rat brain. Neuroreport, 1991. 2(8): p. 445-8.
69. Richter, P., et al., Enhanced development of morphine tolerance in rats treated with 2-deoxy-D-galactose. Psychopharmacology (Berl), 1991. 104(2): p. 279-83.

Primary Affiliation: Leibniz-Institute for Neurobiology - Magdeburg , Germany

Specialties:

Additional Specialties:

Research Interests:


View Dr. Karl-Heinz Smalla’s Resume / CV

Education

Dec 1983
Martin-Luther-University Halle-Wittenberg
PhD in Physical Chemistry
summa cum laude
Sep 1979 - Aug 1983
Martin-Luther-Universitat Halle-Wittenberg
PhD
Physical Chemistry
Sep 1974 - Aug 1979
Martin-Luther-Universitat Halle-Wittenberg
Diploma
Physics
Aug 1979
Martin-Luther-University Halle-Wittenberg
Diploma in Physics
excellent

Experience

Mar 1999 - Feb 2001
Otto von Guericke Universität Magdeburg
Researcher
Institute for Medical Neurobiology
Jan 1998 - Aug 1999
Otto von Guericke Universität Magdeburg
Postdoc
Pharmacology and Toxicology
Jan 1992 - Dec 1997
Institute for Neurobiology
Postdoc
Neurochemistry and Molecular Biology
Sep 1983 - Dec 1991
Institute for Neurobiology and Brain Research
Staff Scientist
Neurochemstry
Mar 2001
Leibniz-Institut für Neurobiologie
Researcher/PI
Special Lab for Molecular Biology Techniques

Publications

51Publications

1225Reads

421Profile Views

673PubMed Central Citations

SynGO: An Evidence-Based, Expert-Curated Knowledge Base for the Synapse.

Neuron 2019 07 3;103(2):217-234.e4. Epub 2019 Jun 3.

Department of Functional Genomics, CNCR, VU University and UMC Amsterdam, 1081 HV Amsterdam, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.neuron.2019.05.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6764089PMC
July 2019
16 Reads
15.054 Impact Factor

Chronic Toxoplasma infection is associated with distinct alterations in the synaptic protein composition.

J Neuroinflammation 2018 Aug 1;15(1):216. Epub 2018 Aug 1.

Institute of Inflammation and Neurodegeneration, Otto von Guericke University Magdeburg, Magdeburg, Germany.

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http://dx.doi.org/10.1186/s12974-018-1242-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6090988PMC
August 2018
12 Reads
5.410 Impact Factor

Contribution of iron and protein contents from rat brain subcellular fractions to MR phase imaging.

Magn Reson Med 2017 05 7;77(5):2028-2039. Epub 2016 Jun 7.

Dept. Biomedical Magnetic Resonance, Otto-von-Guericke University, Magdeburg, Germany.

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http://dx.doi.org/10.1002/mrm.26288DOI Listing
May 2017
8 Reads
3.571 Impact Factor

14-3-3 Proteins regulate K 5.1 surface expression on T lymphocytes.

Traffic 2017 01 27;18(1):29-43. Epub 2016 Nov 27.

Department of Neurology, Westfälische Wilhelms-Universität, Münster, Germany.

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http://dx.doi.org/10.1111/tra.12455DOI Listing
January 2017
84 Reads
2 Citations
4.350 Impact Factor

Genetically Induced Retrograde Amnesia of Associative Memories After Neuroplastin Ablation.

Biol Psychiatry 2017 01 11;81(2):124-135. Epub 2016 Apr 11.

Neurogenetics Special Laboratory, Leibniz Institute for Neurobiology, Magdeburg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.biopsych.2016.03.2107DOI Listing
January 2017
28 Reads
5 Citations
10.260 Impact Factor

Differential effects of dopamine signalling on long-term memory formation and consolidation in rodent brain.

Proteome Sci 2015 18;13:13. Epub 2015 Mar 18.

Special Lab Molecular Biological Techniques, Leibniz Institute for Neurobiology, Magdeburg, 39118 Germany ; Center for Behavioral Brain Sciences, Magdeburg, 39106 Germany.

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http://dx.doi.org/10.1186/s12953-015-0069-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4387680PMC
April 2015
29 Reads
6 Citations
1.730 Impact Factor

The Neuroplastin adhesion molecules: key regulators of neuronal plasticity and synaptic function.

J Neurochem 2014 Nov 14;131(3):268-83. Epub 2014 Aug 14.

School of Biological Sciences, Royal Holloway University of London, Egham, UK.

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http://dx.doi.org/10.1111/jnc.12816DOI Listing
November 2014
15 Reads
10 Citations
4.281 Impact Factor

Distinct set of kinases induced after retrieval of spatial memory discriminate memory modulation processes in the mouse hippocampus.

Hippocampus 2013 Aug 22;23(8):672-83. Epub 2013 May 22.

Department of Pediatrics, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1002/hipo.22127DOI Listing
August 2013
12 Reads
1 Citation
4.162 Impact Factor

Accurate quantification of water-macromolecule exchange induced frequency shift: effects of reference substance.

Magn Reson Med 2013 Jan 28;69(1):263-8. Epub 2012 Feb 28.

Department of Biomedical Magnetic Resonance, Otto-von-Guericke University, Magdeburg, Germany.

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http://dx.doi.org/10.1002/mrm.24223DOI Listing
January 2013
29 Reads
2 Citations
3.571 Impact Factor

Increased density of prohibitin-immunoreactive oligodendrocytes in the dorsolateral prefrontal white matter of subjects with schizophrenia suggests extraneuronal roles for the protein in the disease.

Neuromolecular Med 2012 Dec 19;14(4):270-80. Epub 2012 Jun 19.

Department of Psychiatry, University of Magdeburg, Leipziger Str. 44, 39120, Magdeburg, Germany.

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http://dx.doi.org/10.1007/s12017-012-8185-yDOI Listing
December 2012
29 Reads
7 Citations
3.680 Impact Factor

SynProt: A Database for Proteins of Detergent-Resistant Synaptic Protein Preparations.

Front Synaptic Neurosci 2012 25;4. Epub 2012 Jun 25.

Department of Neurochemistry and Molecular Biology, Leibniz Institute for Neurobiology Magdeburg, Germany.

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http://dx.doi.org/10.3389/fnsyn.2012.00001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3382120PMC
October 2012
38 Reads
15 Citations

Neuroplastin expression in the hippocampus of mice lacking complex gangliosides.

J Mol Neurosci 2012 Sep 26;48(1):161-6. Epub 2012 May 26.

Croatian Institute for Brain Research, School of Medicine, University of Zagreb, Šalata 12, 10000, Zagreb, Croatia.

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http://dx.doi.org/10.1007/s12031-012-9801-xDOI Listing
September 2012
12 Reads
2.343 Impact Factor

Synaptic proteome changes in mouse brain regions upon auditory discrimination learning.

Proteomics 2012 Aug;12(15-16):2433-44

Institute of Experimental Internal Medicine, Medical School, Otto von Guericke University, Magdeburg, Germany.

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http://dx.doi.org/10.1002/pmic.201100669DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3509369PMC
August 2012
33 Reads
10 Citations
3.810 Impact Factor

The cell adhesion molecule neuroplastin-65 is a novel interaction partner of γ-aminobutyric acid type A receptors.

J Biol Chem 2012 Apr 2;287(17):14201-14. Epub 2012 Mar 2.

Center for Brain Research, Department of Biochemistry and Molecular Biology of the Nervous System, Medical University of Vienna, 1090 Vienna, Austria.

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http://dx.doi.org/10.1074/jbc.M111.293175DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3340160PMC
April 2012
12 Reads
11 Citations
4.573 Impact Factor

Dopamine modulates memory consolidation of discrimination learning in the auditory cortex.

Eur J Neurosci 2012 Mar 17;35(5):763-74. Epub 2012 Feb 17.

Special Lab Molecular Biological Techniques, Leibniz Institute for Neurobiology, Brenneckestrasse 6, D-39118 Magdeburg, Germany.

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http://dx.doi.org/10.1111/j.1460-9568.2012.07994.xDOI Listing
March 2012
15 Reads
10 Citations
3.181 Impact Factor

Homeostatic NMDA receptor down-regulation via brain derived neurotrophic factor and nitric oxide-dependent signalling in cortical but not in hippocampal neurons.

J Neurochem 2011 Sep 18;118(5):760-72. Epub 2011 Jul 18.

Laboratorio de Neurotoxicología Ambiental, Facultad de Medicina, Universidad Católica del Norte, Coquimbo, Chile.

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http://dx.doi.org/10.1111/j.1471-4159.2011.07365.xDOI Listing
September 2011
11 Reads
4 Citations
4.281 Impact Factor

TRPV1 acts as a synaptic protein and regulates vesicle recycling.

J Cell Sci 2010 Jun 18;123(Pt 12):2045-57. Epub 2010 May 18.

Signal Transduction in Pain and Mental Retardation, Department for Molecular Human Genetics, Max-Planck Institute for Molecular Genetics, Berlin, Germany.

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http://dx.doi.org/10.1242/jcs.065144DOI Listing
June 2010
20 Reads
13 Citations
5.432 Impact Factor

Congenital lack of nNOS impairs long-term social recognition memory and alters the olfactory bulb proteome.

Neurobiol Learn Mem 2009 Nov 14;92(4):469-84. Epub 2009 Jun 14.

Otto-von-Guericke-Universität, Institut für Biochemie und Zellbiologie, Leipziger Strasse 44, D-39120, Magdeburg, Germany.

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http://dx.doi.org/10.1016/j.nlm.2009.06.004DOI Listing
November 2009
10 Reads
9 Citations
3.652 Impact Factor

Altered postsynaptic-density-levels of caldendrin in the para-chloroamphetamine-induced serotonin syndrome but not in the rat ketamine model of psychosis.

Neurochem Res 2009 Aug 18;34(8):1405-9. Epub 2009 Feb 18.

Special Lab Molecular Biological Techniques, Leibniz-Institute for Neurobiology, Magdeburg, Germany.

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http://dx.doi.org/10.1007/s11064-009-9925-8DOI Listing
August 2009
10 Reads
2 Citations
2.593 Impact Factor

Calneurons provide a calcium threshold for trans-Golgi network to plasma membrane trafficking.

Proc Natl Acad Sci U S A 2009 Jun 19;106(22):9093-8. Epub 2009 May 19.

Project Group Neuroplasticity, Leibniz Institute for Neurobiology, 39118 Magdeburg, Germany.

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http://dx.doi.org/10.1073/pnas.0903001106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2690001PMC
June 2009
18 Reads
22 Citations
9.810 Impact Factor

Dopaminergic modulation of auditory cortex-dependent memory consolidation through mTOR.

Cereb Cortex 2008 Nov 4;18(11):2646-58. Epub 2008 Mar 4.

Leibniz Institute for Neurobiology, D-39118 Magdeburg, Germany.

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http://dx.doi.org/10.1093/cercor/bhn026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2567422PMC
November 2008
15 Reads
27 Citations
8.665 Impact Factor

Scaffolding proteins in highly purified rat olfactory cilia membranes.

Neuroreport 2008 Jul;19(11):1123-6

Department of Biology, Faculty of Sciences, University of Chile, Santiago, Chile.

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http://dx.doi.org/10.1097/WNR.0b013e3283086797DOI Listing
July 2008
13 Reads
2 Citations
1.644 Impact Factor

A reduced number of cortical neurons show increased Caldendrin protein levels in chronic schizophrenia.

Schizophr Res 2007 Nov 23;96(1-3):246-56. Epub 2007 Aug 23.

Department of Psychiatry, Faculty of Medicine, Otto-von-Guericke University, Leipziger Str. 44, 39120 Magdeburg, Germany.

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http://dx.doi.org/10.1016/j.schres.2007.05.038DOI Listing
November 2007
27 Reads
8 Citations
3.923 Impact Factor

Splice-isoform specific immunolocalization of neuronal nitric oxide synthase in mouse and rat brain reveals that the PDZ-complex-building nNOSalpha beta-finger is largely exposed to antibodies.

Dev Neurobiol 2007 Mar;67(4):422-37

Institut für Medizinische Neurobiologie, Otto-von-Guericke-Universität Magdeburg, Leipziger Str. 44, 39120 Magdeburg, Germany.

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http://dx.doi.org/10.1002/dneu.20317DOI Listing
March 2007
61 Reads
1 Citation
3.370 Impact Factor

The immunolocalization of the synaptic glycoprotein neuroplastin differs substantially between the human and the rodent brain.

Brain Res 2007 Feb 27;1134(1):107-12. Epub 2006 Dec 27.

Department of Psychiatry, Faculty of Medicine, Otto-von-Guericke University, Magdeburg, Germany.

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http://dx.doi.org/10.1016/j.brainres.2006.11.090DOI Listing
February 2007
20 Reads
4 Citations
2.843 Impact Factor

Neuronal Ca2+ signaling via caldendrin and calneurons.

Biochim Biophys Acta 2006 Nov 6;1763(11):1229-37. Epub 2006 Sep 6.

AG Molecular Mechanisms of Plasticity, Department of Neurochemistry/Molecular Biology, Leibniz Institute for Neurobiology, Brenneckestrasse 6, 39118 Magdeburg, Germany.

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http://dx.doi.org/10.1016/j.bbamcr.2006.08.047DOI Listing
November 2006
13 Reads
22 Citations

Brevican-containing perineuronal nets of extracellular matrix in dissociated hippocampal primary cultures.

Mol Cell Neurosci 2006 Apr 28;31(4):774-84. Epub 2006 Feb 28.

Department for Neurochemistry and Molecular Biology, Leibniz Institute for Neurobiology Magdeburg, Germany.

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http://dx.doi.org/10.1016/j.mcn.2006.01.011DOI Listing
April 2006
12 Reads
26 Citations
3.840 Impact Factor

Organelle proteomics of rat synaptic proteins: correlation-profiling by isotope-coded affinity tagging in conjunction with liquid chromatography-tandem mass spectrometry to reveal post-synaptic density specific proteins.

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http://dx.doi.org/10.1021/pr049802+DOI Listing
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4.250 Impact Factor

Impaired synaptic function in the microglial KARAP/DAP12-deficient mouse.

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http://dx.doi.org/10.1523/JNEUROSCI.2251-04.2004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6730361PMC
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Caldendrin but not calmodulin binds to light chain 3 of MAP1A/B: an association with the microtubule cytoskeleton highlighting exclusive binding partners for neuronal Ca(2+)-sensor proteins.

J Mol Biol 2004 Feb;336(4):957-70

AG Molecular Mechanisms of Plasticity, Department of Neurochemistry/Molecular Biology, Leibniz Institute for Neurobiology, Brenneckestr. 6 39118 Magdeburg, Germany.

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February 2004
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20 Citations
4.333 Impact Factor

Proteomics analysis of rat brain postsynaptic density. Implications of the diverse protein functional groups for the integration of synaptic physiology.

J Biol Chem 2004 Jan 7;279(2):987-1002. Epub 2003 Oct 7.

Department of Molecular and Cellular Neurobiology, Research Institute of Neurosciences, Vrije Universiteit, De Boelelaan 1085, 1081 HV Amsterdam, The Netherlands.

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http://dx.doi.org/10.1074/jbc.M303116200DOI Listing
January 2004
19 Reads
56 Citations
4.573 Impact Factor

Distribution and cellular localization of caldendrin immunoreactivity in adult human forebrain.

J Histochem Cytochem 2003 Aug;51(8):1109-12

Department of Psychiatry, Otto-von-Guericke-University, Magdeburg, Germany.

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http://dx.doi.org/10.1177/002215540305100816DOI Listing
August 2003
12 Reads
4 Citations
1.960 Impact Factor

Kainate-induced epileptic seizures induce a recruitment of caldendrin to the postsynaptic density in rat brain.

Brain Res Mol Brain Res 2003 Aug;116(1-2):159-62

AG Molecular Mechanisms of Plasticity, Department of Neurochemistry/Molecular Biology, Leibniz-Institute for Neurobiology, Brenneckestrasse 6, Magdeburg 39118, Germany.

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http://dx.doi.org/10.1016/s0169-328x(03)00235-3DOI Listing
August 2003
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Gliap--a novel untypical L-asparaginase localized to rat brain astrocytes.

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AG Molecular Mechanisms of Plasticity, Department of Neurochemistry and Molecular Biology, Leibniz Institute for Neurobiology, Magdeburg, Germany.

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http://dx.doi.org/10.1046/j.1471-4159.2003.01766.xDOI Listing
June 2003
14 Reads
4 Citations
4.281 Impact Factor

Expression of the immunoglobulin superfamily neuroplastin adhesion molecules in adult and developing mouse cerebellum and their localisation to parasagittal stripes.

J Comp Neurol 2003 Jun;462(3):286-301

Department of Cell Biology and Anatomy, Genes and Development Research Group, Faculty of Medicine, University of Calgary, Calgary, Alberta T2N 4N1, Canada.

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http://dx.doi.org/10.1002/cne.10719DOI Listing
June 2003
10 Reads
10 Citations
3.230 Impact Factor

Brevican isoforms associate with neural membranes.

J Neurochem 2002 Nov;83(3):738-46

AG Molecular Mechanisms of Plasticity, Department of Neurochemistry/Molecular Biology, Leibniz Institute for Neurobiology, 39118 Magdeburg, Germany.

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http://dx.doi.org/10.1046/j.1471-4159.2002.01183.xDOI Listing
November 2002
10 Reads
8 Citations
4.281 Impact Factor

Nicotinic acetylcholine receptors of Drosophila: three subunits encoded by genomically linked genes can co-assemble into the same receptor complex.

J Neurochem 2002 Jan;80(1):149-57

Leibniz Institute for Neurobiology, Department of Neurochemistry and Molecular Biology, Magdeburg, Germany.

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http://dx.doi.org/10.1046/j.0022-3042.2001.00685.xDOI Listing
January 2002
14 Reads
11 Citations
4.281 Impact Factor

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