Karl Rohr

Karl Rohr

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Karl Rohr

Karl Rohr

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Combined automated 3D volumetry by pulmonary CT angiography and echocardiography for detection of pulmonary hypertension.

Eur Radiol 2019 Nov 8;29(11):6059-6068. Epub 2019 Apr 8.

Department of Diagnostic and Interventional Radiology, Heidelberg University Hospital, Im Neuenheimer Feld 110, 69120, Heidelberg, Germany.

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http://dx.doi.org/10.1007/s00330-019-06188-7DOI Listing
November 2019

Hyperparameter optimization for image analysis: application to prostate tissue images and live cell data of virus-infected cells.

Int J Comput Assist Radiol Surg 2019 Nov 8;14(11):1847-1857. Epub 2019 Jun 8.

Biomedical Computer Vision Group, BioQuant, IPMB, University of Heidelberg and DKFZ, Im Neuenheimer Feld 267, Heidelberg, Germany.

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http://dx.doi.org/10.1007/s11548-019-02010-3DOI Listing
November 2019

A Global Method for Non-Rigid Registration of Cell Nuclei in Live Cell Time-Lapse Images.

Authors:
Qi Gao Karl Rohr

IEEE Trans Med Imaging 2019 10 27;38(10):2259-2270. Epub 2019 Feb 27.

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https://ieeexplore.ieee.org/document/8653983/
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http://dx.doi.org/10.1109/TMI.2019.2901918DOI Listing
October 2019

DNA accessibility of chromatosomes quantified by automated image analysis of AFM data.

Sci Rep 2019 Sep 4;9(1):12788. Epub 2019 Sep 4.

Heidelberg University, BioQuant and IPMB, Biomedical Computer Vision Group, Heidelberg, 69120, Germany.

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http://dx.doi.org/10.1038/s41598-019-49163-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6726762PMC
September 2019

Spatiotemporal Coupling of the Hepatitis C Virus Replication Cycle by Creating a Lipid Droplet- Proximal Membranous Replication Compartment.

Cell Rep 2019 Jun;27(12):3602-3617.e5

Department of Infectious Diseases, Molecular Virology, Heidelberg University, Im Neuenheimer Feld 344, 69120 Heidelberg, Germany; German Center for Infection Research, Heidelberg Partner Site, Im Neuenheimer Feld 344, 69120 Heidelberg, Germany; Division of Virus-Associated Carcinogenesis, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 242, Heidelberg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2019.05.063DOI Listing
June 2019

Experimental and computational analyses reveal that environmental restrictions shape HIV-1 spread in 3D cultures.

Nat Commun 2019 05 13;10(1):2144. Epub 2019 May 13.

Department of Infectious Diseases, Centre for Integrative Infectious Disease Research (CIID), Integrative Virology, University Hospital Heidelberg, 69120, Heidelberg, Germany.

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http://dx.doi.org/10.1038/s41467-019-09879-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6514199PMC
May 2019

Reciprocal Effects of Fibroblast Growth Factor Receptor Signaling on Dengue Virus Replication and Virion Production.

Cell Rep 2019 05;27(9):2579-2592.e6

Department of Infectious Diseases, Molecular Virology, Heidelberg University, Im Neuenheimer Feld 344, Heidelberg 69120, Germany; German Center for Infection Research, Heidelberg Partner Site, Im Neuenheimer Feld 344, Heidelberg 69120, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2019.04.105DOI Listing
May 2019

Determination of the Maximum Velocity of Filaments in the Motility Assay.

Front Physiol 2019 27;10:289. Epub 2019 Mar 27.

Biomedical Computer Vision Group, BioQuant Center and IPMB, University of Heidelberg and DKFZ, Heidelberg, Germany.

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http://dx.doi.org/10.3389/fphys.2019.00289DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6445948PMC
March 2019

Rigid and non-rigid registration of polarized light imaging data for 3D reconstruction of the temporal lobe of the human brain at micrometer resolution.

Neuroimage 2018 11 6;181:235-251. Epub 2018 Jul 6.

Dept. of Bioinformatics and Functional Genomics, Biomedical Computer Vision Group, BIOQUANT, IPMB, University of Heidelberg, Germany; German Cancer Research Center (DKFZ), Germany.

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http://dx.doi.org/10.1016/j.neuroimage.2018.06.084DOI Listing
November 2018

Development of a new software and test setup for analyzing hVOR in very young children by vHIT.

J Vestib Res 2017 ;27(2-3):155-162

Section of Phoniatrics, Pedaudiology and Neurootology, Department of Otorhinolaryngology, Head and Neck Surgery, University Medical Centre Mannheim, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany.

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http://dx.doi.org/10.3233/VES-170611DOI Listing
June 2018

Progressive Minimal Path Method for Segmentation of 2D and 3D Line Structures.

IEEE Trans Pattern Anal Mach Intell 2018 03 6;40(3):696-709. Epub 2017 Apr 6.

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http://dx.doi.org/10.1109/TPAMI.2017.2691709DOI Listing
March 2018

Workflows for microscopy image analysis and cellular phenotyping.

J Biotechnol 2017 Nov 27;261:70-75. Epub 2017 Jul 27.

High-Content Analysis of the Cell (HiCell) and ViroQuant-CellNetworks RNAi Screening Facility, BioQuant, University of Heidelberg, Im Neuenheimer Feld 267, 69120 Heidelberg, Germany.

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http://dx.doi.org/10.1016/j.jbiotec.2017.07.019DOI Listing
November 2017

Automated 3D Volumetry of the Pulmonary Arteries based on Magnetic Resonance Angiography Has Potential for Predicting Pulmonary Hypertension.

PLoS One 2016 14;11(9):e0162516. Epub 2016 Sep 14.

Translational Lung Research Center (TLRC), Member of the German Center for Lung Research (DZL), University of Heidelberg, Im Neuenheimer Feld 110, 69120 Heidelberg, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0162516PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5023190PMC
August 2017

Diffeomorphic Multi-Frame Non-Rigid Registration of Cell Nuclei in 2D and 3D Live Cell Images.

IEEE Trans Image Process 2017 Mar 16;26(3):1405-1417. Epub 2017 Jan 16.

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http://dx.doi.org/10.1109/TIP.2017.2653360DOI Listing
March 2017

Quantification of telomere features in tumor tissue sections by an automated 3D imaging-based workflow.

Methods 2017 02 7;114:60-73. Epub 2016 Oct 7.

Research Group Genome Organization & Function, German Cancer Research Center (DKFZ) and Bioquant Center, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.ymeth.2016.09.014DOI Listing
February 2017

Phosphorylation-Dependent Feedback Inhibition of RIG-I by DAPK1 Identified by Kinome-wide siRNA Screening.

Mol Cell 2017 Feb 26;65(3):403-415.e8. Epub 2017 Jan 26.

Research Group "Dynamics of early viral infection and the innate antiviral response," Division Virus-associated carcinogenesis (F170), German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany; Department for Infectious Diseases, Molecular Virology, Research Group "Dynamics of early viral infection and the innate antiviral response," Medical Faculty, Heidelberg University, 69120 Heidelberg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2016.12.021DOI Listing
February 2017

3D Geometric Analysis of the Pediatric Aorta in 3D MRA Follow-Up Images with Application to Aortic Coarctation.

Methods Inf Med 2016 Oct 13;55(5):455-462. Epub 2016 Jul 13.

Stefan Wörz, BioQuant Center, BQ 20, Im Neuenheimer Feld 267, 69120 Heidelberg, Germany, E-mail:

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http://dx.doi.org/10.3414/ME15-01-0104DOI Listing
October 2016

A spherical harmonics intensity model for 3D segmentation and 3D shape analysis of heterochromatin foci.

Med Image Anal 2016 08 17;32:18-31. Epub 2016 Mar 17.

Biomedical Computer Vision Group, Department Bioinformatics and Functional Genomics, University of Heidelberg, IPMB, BioQuant, and German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.media.2016.03.001DOI Listing
August 2016

High-Throughput RNAi Screening Identifies a Role for the Osteopontin Pathway in Proliferation and Migration of Human Aortic Smooth Muscle Cells.

Cardiovasc Drugs Ther 2016 Jun;30(3):281-95

Clinic for Vascular and Endovascular Surgery, University Hospital, Frankfurt, Germany.

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http://dx.doi.org/10.1007/s10557-016-6663-4DOI Listing
June 2016

Automated Analysis of Single-Molecule Photobleaching Data by Statistical Modeling of Spot Populations.

Biophys J 2015 Dec;109(11):2352-62

Division of Theoretical Bioinformatics (B080), German Cancer Research Center (DKFZ), Heidelberg, Germany; Department for Bioinformatics and Functional Genomics, Institute for Pharmacy and Molecular Biotechnology (IPMB) and BioQuant, Heidelberg University, Heidelberg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.bpj.2015.10.035DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4675885PMC
December 2015

Performance and sensitivity evaluation of 3D spot detection methods in confocal microscopy.

Cytometry A 2015 Aug 28;87(8):759-72. Epub 2015 May 28.

Centre for Biomedical Image Analysis, Faculty of Informatics, Masaryk University, Brno, Czech Republic.

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http://dx.doi.org/10.1002/cyto.a.22692DOI Listing
August 2015

Large-scale tracking and classification for automatic analysis of cell migration and proliferation, and experimental optimization of high-throughput screens of neuroblastoma cells.

Cytometry A 2015 Jun 28;87(6):524-40. Epub 2015 Jan 28.

Department of Bioinformatics and Functional Genomics, Biomedical Computer Vision Group, BioQuant and Institute of Pharmacy and Molecular Biotechnology (IPMB), Heidelberg University, 69120, Heidelberg, Germany.

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http://dx.doi.org/10.1002/cyto.a.22632DOI Listing
June 2015

Aortic morphometry at endograft position as assessed by 3D image analysis affects risk of type I endoleak formation after TEVAR.

Langenbecks Arch Surg 2015 May 22;400(4):523-9. Epub 2015 Feb 22.

Department of Vascular and Endovascular Surgery, Heidelberg University Hospital, Im Neuenheimer Feld 110, 69120, Heidelberg, Germany,

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http://link.springer.com/content/pdf/10.1007/s00423-015-1291
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http://link.springer.com/10.1007/s00423-015-1291-1
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http://dx.doi.org/10.1007/s00423-015-1291-1DOI Listing
May 2015

PML induces compaction, TRF2 depletion and DNA damage signaling at telomeres and promotes their alternative lengthening.

J Cell Sci 2015 May 23;128(10):1887-900. Epub 2015 Apr 23.

Research Group Genome Organization & Function, Deutsches Krebsforschungszentrum (DKFZ) & BioQuant, 69120 Heidelberg, Germany

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http://dx.doi.org/10.1242/jcs.148296DOI Listing
May 2015

Non-rigid multi-frame registration of cell nuclei in live cell fluorescence microscopy image data.

Med Image Anal 2015 Jan 11;19(1):1-14. Epub 2014 Aug 11.

Dept. Bioinformatics and Functional Genomics, Biomedical Computer Vision Group, University of Heidelberg, BioQuant, IPMB, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 267, 69120 Heidelberg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.media.2014.07.006DOI Listing
January 2015

Characterizing protein interactions employing a genome-wide siRNA cellular phenotyping screen.

PLoS Comput Biol 2014 Sep 25;10(9):e1003814. Epub 2014 Sep 25.

Network Modeling, Leibniz Institute for Natural Product Research and Infection Biology - Hans Knöll Institute Jena, Jena, Germany; Integrated Research and Treatment Center, Center for Sepsis Control and Care (CSCC), Jena University Hospital, Jena, Germany; Theoretical Bioinformatics, German Cancer Research Center, Heidelberg, Germany.

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http://dx.doi.org/10.1371/journal.pcbi.1003814DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4178005PMC
September 2014

An inducible hepatocellular carcinoma model for preclinical evaluation of antiangiogenic therapy in adult mice.

Cancer Res 2014 Aug 6;74(15):4157-69. Epub 2014 Jun 6.

Division of Vascular Oncology and Metastasis, German Cancer Research Center Heidelberg (DKFZ-ZMBH Alliance), Heidelberg, Germany. Department of Vascular Biology and Tumor Angiogenesis (CBTM), Medical Faculty Mannheim, Heidelberg University, Heidelberg, Germany. German Cancer Consortium, Heidelberg, Germany.

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http://dx.doi.org/10.1158/0008-5472.CAN-13-2311DOI Listing
August 2014

Investigating the role of F-actin in human immunodeficiency virus assembly by live-cell microscopy.

J Virol 2014 Jul 30;88(14):7904-14. Epub 2014 Apr 30.

Department of Infectious Diseases, Virology, University Hospital Heidelberg, Heidelberg, Germany

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http://dx.doi.org/10.1128/JVI.00431-14DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4097803PMC
July 2014

A benchmark for comparison of cell tracking algorithms.

Bioinformatics 2014 Jun 12;30(11):1609-17. Epub 2014 Feb 12.

Center for Biomedical Image Analysis, Masaryk University, 602 00 Brno, Czech Republic, Cancer Imaging Laboratory, Oncology Division, Center for Applied Medical Research, University of Navarra, 31008 Pamplona, Spain, Biomedical Imaging Group Rotterdam, Erasmus University Medical Center, 3015 GE Rotterdam, The Netherlands, Fusion Technology and Systems Department, Compunetix Inc., Monroeville, PA 15146, USA, Biomedical Computer Vision Group, Department of Bioinformatics and Functional Genomics, University of Heidelberg, BIOQUANT, IPMB and DKFZ, 69120 Heidelberg, Germany, KTH Royal Institute of Technology, ACCESS Linnaeus Center, Department of Signal Processing, 100 44 Stockholm, Sweden, Baxter Laboratory for Stem Cell Biology, Department of Microbiology and Immunology, Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA, Division of Image Processing, Leiden University Medical Center, 2300 RC Leiden, The Netherlands, Institute of Cellular Biology and Pathology, First Faculty of Medicine, Charles University in Prague, 12801 Prague 2, Czech Republic and Biomedical Image Technologies, Universidad Politécnica de Madrid & CIBER BBN, 28040 Madrid, Spain.

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http://dx.doi.org/10.1093/bioinformatics/btu080DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4029039PMC
June 2014

3D morphometry using automated aortic segmentation in native MR angiography: an alternative to contrast enhanced MRA?

Cardiovasc Diagn Ther 2014 Apr;4(2):80-7

1 Department of Diagnostic and Interventional Radiology, University Hospital Heidelberg, Germany ; 2 Department of Radiology, German Cancer Research Center, Heidelberg, Germany ; 3 Dept. Bioinformatics and Functional Genomics, Biomedical Computer Vision Group, University of Heidelberg, BIOQUANT, IPMB, and DKFZ Heidelberg; 4 Department of Vascular and Endovascular Surgery, University Hospital Heidelberg, Germany ; 5 Institute of Diagnostic, Interventional and Pediatric Radiology, University Hospital Bern, Inselspital, Bern, Switzerland.

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http://dx.doi.org/10.3978/j.issn.2223-3652.2013.10.06DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3996235PMC
April 2014

Chromosome segregation by the Escherichia coli Min system.

Mol Syst Biol 2013 ;9:686

Zentrum für Molekulare Biologie der Universität Heidelberg, DKFZ-ZMBH Alliance, Heidelberg, Germany.

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http://dx.doi.org/10.1038/msb.2013.44DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3792344PMC
March 2014

Globally optimal curvature-regularized fast marching for vessel segmentation.

Med Image Comput Comput Assist Interv 2013 ;16(Pt 1):550-7

Dept. Bioinformatics and Functional Genomics, Biomedical Computer Vision Group, University of Heidelberg, BIOQUANT, IPMB, and DKFZ Heidelberg.

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http://dx.doi.org/10.1007/978-3-642-40811-3_69DOI Listing
February 2014

True four-dimensional analysis of thoracic aortic displacement and distension using model-based segmentation of computed tomography angiography.

Int J Cardiovasc Imaging 2014 Jan 18;30(1):185-94. Epub 2013 Oct 18.

Diagnostic and Interventional Radiology, University Medical Center Heidelberg, INF 110, 69120, Heidelberg, Germany,

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http://dx.doi.org/10.1007/s10554-013-0307-6DOI Listing
January 2014

Overlapping gene coexpression patterns in human medullary thymic epithelial cells generate self-antigen diversity.

Proc Natl Acad Sci U S A 2013 Sep 26;110(37):E3497-505. Epub 2013 Aug 26.

Division of Developmental Immunology, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany.

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http://dx.doi.org/10.1073/pnas.1308311110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3773787PMC
September 2013

Time-lapse imaging of neuroblastoma cells to determine cell fate upon gene knockdown.

PLoS One 2012 12;7(12):e50988. Epub 2012 Dec 12.

Department of Bioinformatics and Functional Genomics, Institute of Pharmacy and Molecular Biotechnology, Bioquant, University of Heidelberg, Heidelberg, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0050988PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3521006PMC
June 2013

Xenopus cytoplasmic linker-associated protein 1 (XCLASP1) promotes axon elongation and advance of pioneer microtubules.

Mol Biol Cell 2013 May 20;24(10):1544-58. Epub 2013 Mar 20.

Exzellenzcluster CellNetworks, University of Heidelberg, 69120 Heidelberg, Germany.

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http://dx.doi.org/10.1091/mbc.E12-08-0573DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3655815PMC
May 2013

Measurements of lenticulostriate arteries using 7T MRI: new imaging markers for subcortical vascular dementia.

J Neurol Sci 2012 Nov 2;322(1-2):200-5. Epub 2012 Jun 2.

Department of Neurology, Sungkyunkwan University School of Medicine, Samsung Medical Center, Seoul, Korea.

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http://dx.doi.org/10.1016/j.jns.2012.05.032DOI Listing
November 2012

Efficient globally optimal segmentation of cells in fluorescence microscopy images using level sets and convex energy functionals.

Med Image Anal 2012 Oct 21;16(7):1436-44. Epub 2012 Jun 21.

University of Heidelberg, BIOQUANT, IPMB, and DKFZ Heidelberg, Dept. of Bioinformatics and Functional Genomics, Biomedical Computer Vision Group, Im Neuenheimer Feld 267, 69120 Heidelberg, Germany.

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https://linkinghub.elsevier.com/retrieve/pii/S13618415120007
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http://dx.doi.org/10.1016/j.media.2012.05.012DOI Listing
October 2012

Identifying virus-cell fusion in two-channel fluorescence microscopy image sequences based on a layered probabilistic approach.

IEEE Trans Med Imaging 2012 Sep 6;31(9):1786-808. Epub 2012 Jun 6.

Department Bioinformatics and Functional Genomics, University of Heidelberg, Heidelberg, Germany.

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http://dx.doi.org/10.1109/TMI.2012.2203142DOI Listing
September 2012

Segmentation and quantification of the aortic arch using joint 3D model-based segmentation and elastic image registration.

Med Image Anal 2012 Aug 21;16(6):1187-201. Epub 2012 Jun 21.

Department of Bioinformatics and Functional Genomics, University of Heidelberg, BIOQUANT, IPMB, and DKFZ Heidelberg, Germany.

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http://dx.doi.org/10.1016/j.media.2012.05.010DOI Listing
August 2012

A three-dimensional colocalization RNA interference screening platform to elucidate the alternative lengthening of telomeres pathway.

Biotechnol J 2012 Jan 7;7(1):103-16. Epub 2011 Jun 7.

Research Group Genome Organization and Function, DKFZ and BioQuant, Heidelberg, Germany.

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http://dx.doi.org/10.1002/biot.201000474DOI Listing
January 2012

Normalizing for individual cell population context in the analysis of high-content cellular screens.

BMC Bioinformatics 2011 Dec 20;12:485. Epub 2011 Dec 20.

Heidelberg University, ViroQuant Research Group Modeling, BioQuant BQ26, Im Neuenheimer Feld 267, 69120 Heidelberg, Germany.

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http://dx.doi.org/10.1186/1471-2105-12-485DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3259109PMC
December 2011

Model-based segmentation and motion analysis of the thoracic aorta from 4D ECG-gated CTA images.

Med Image Comput Comput Assist Interv 2011 ;14(Pt 1):589-96

University of Heidelberg, BIOQUANT, IPMB, and DKFZ Heidelberg Dept. Bioinformatics and Functional Genomics, Biomedical Computer Vision Group.

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http://dx.doi.org/10.1007/978-3-642-23623-5_74DOI Listing
November 2011

Fast globally optimal segmentation of cells in fluorescence microscopy images.

Med Image Comput Comput Assist Interv 2011 ;14(Pt 1):645-52

University of Heidelberg, BIOQUANT, IPMB, and DKFZ Heidelberg, Dept. Bioinformatics and Functional Genomics, Biomedical Computer Vision Group.

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http://dx.doi.org/10.1007/978-3-642-23623-5_81DOI Listing
November 2011

Development of in vivo quantitative geometric mapping of the aortic arch for advanced endovascular aortic repair: feasibility and preliminary results.

J Vasc Interv Radiol 2011 Jul 3;22(7):980-6. Epub 2011 Apr 3.

Department of Diagnostic and Interventional Radiology, University Hospital Heidelberg, Im Neuenheimer Feld 110, 69120 Heidelberg, Germany.

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http://dx.doi.org/10.1016/j.jvir.2011.01.434DOI Listing
July 2011

Herpesviral replication compartments move and coalesce at nuclear speckles to enhance export of viral late mRNA.

Proc Natl Acad Sci U S A 2011 May 9;108(21):E136-44. Epub 2011 May 9.

Department of Microbiology and Molecular Genetics, Harvard Medical School, Boston, MA 02115, USA.

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http://dx.doi.org/10.1073/pnas.1103411108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3102408PMC
May 2011

Nonrigid registration of 2-D and 3-D dynamic cell nuclei images for improved classification of subcellular particle motion.

IEEE Trans Image Process 2011 Apr 13;20(4):1011-22. Epub 2010 Sep 13.

Biomedical Computer Vision Group, Department of Bioinformatics and Functional Genomics, University of Heidelberg, D-69120 Heidelberg, Germany.

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http://dx.doi.org/10.1109/TIP.2010.2076377DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3282047PMC
April 2011

Combined model-based segmentation and elastic registration for accurate quantification of the aortic arch.

Med Image Comput Comput Assist Interv 2010 ;13(Pt 1):444-51

Dept. Bioinformatics and Functional Genomics, Biomedical Computer Vision Group, University of Heidelberg, BIOQUANT, IPMB, and DKFZ Heidelberg.

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http://dx.doi.org/10.1007/978-3-642-15705-9_54DOI Listing
November 2010

3-D quantification of the aortic arch morphology in 3-D CTA data for endovascular aortic repair.

IEEE Trans Biomed Eng 2010 Oct 21;57(10):2359-68. Epub 2010 Jun 21.

Department of Bioinformatics and Functional Genomics, Biomedical Computer Vision Group, University of Heidelberg, BIOQUANT, IPMB, and DKFZ Heidelberg, 69120 Heidelberg, Germany.

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http://ieeexplore.ieee.org/iel5/10/5577367/05491100.pdf?arnu
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http://ieeexplore.ieee.org/lpdocs/epic03/wrapper.htm?arnumbe
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http://dx.doi.org/10.1109/TBME.2010.2053539DOI Listing
October 2010

3D geometry-based quantification of colocalizations in multichannel 3D microscopy images of human soft tissue tumors.

IEEE Trans Med Imaging 2010 Aug 17;29(8):1474-84. Epub 2010 Jun 17.

Department Bioinformatics and Functional Genomics, Biomedical Computer Vision Group, University of Heidelberg, IPMB, BIOQUANT, and DKFZ Heidelberg, 69120 Heidelberg, Germany.

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http://ieeexplore.ieee.org/document/5487413/
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http://dx.doi.org/10.1109/TMI.2010.2049857DOI Listing
August 2010

Hybrid spline-based multimodal registration using local measures for joint entropy and mutual information.

Med Image Comput Comput Assist Interv 2009 ;12(Pt 1):607-15

Dept. Bioinformatics and Functional Genomics, Biomedical Computer Vision Group, University of Heidelberg, BIOQUANT, IPMB, and DKFZ Heidelberg.

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http://dx.doi.org/10.1007/978-3-642-04268-3_75DOI Listing
June 2010

FRET imaging of cells transfected with siRNA/liposome complexes.

Methods Mol Biol 2010 ;606:439-55

Department of Bioinformatics and Functional Genomics, German Cancer Research Center, Institute of Pharmacy and Molecular Biotechnology, University of Heidelberg, Germany.

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http://dx.doi.org/10.1007/978-1-60761-447-0_30DOI Listing
March 2010

Automatic analysis of dividing cells in live cell movies to detect mitotic delays and correlate phenotypes in time.

Genome Res 2009 Nov 1;19(11):2113-24. Epub 2009 Oct 1.

University of Heidelberg, IPMB, BIOQUANT, and DKFZ Heidelberg, Department of Bioinformatics and Functional Genomics, Biomedical Computer Vision Group, D-69120 Heidelberg, Germany.

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http://dx.doi.org/10.1101/gr.092494.109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2775592PMC
November 2009

Dynamics of HIV-1 assembly and release.

PLoS Pathog 2009 Nov 6;5(11):e1000652. Epub 2009 Nov 6.

Physical Chemistry, Department of Chemistry and Biochemistry, Munich Center for Integrated Protein Science (CiPSM) and Center for NanoScience, Ludwig-Maximilians-Universität München, Munich, Germany.

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http://dx.doi.org/10.1371/journal.ppat.1000652DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2766258PMC
November 2009

Visualizing fusion of pseudotyped HIV-1 particles in real time by live cell microscopy.

Retrovirology 2009 Sep 18;6:84. Epub 2009 Sep 18.

Department of Virology, Universitätsklinikum Heidelberg, Heidelberg, Germany.

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http://dx.doi.org/10.1186/1742-4690-6-84DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2762461PMC
September 2009

Single-cell-based image analysis of high-throughput cell array screens for quantification of viral infection.

Cytometry A 2009 Apr;75(4):309-18

University of Heidelberg, Department of Bioinformatics and Functional Genomics, BIOQUANT, IPMB, Heidelberg, Germany.

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http://dx.doi.org/10.1002/cyto.a.20662DOI Listing
April 2009

Structural analysis of interphase X-chromatin based on statistical shape theory.

Biochim Biophys Acta 2008 Nov 30;1783(11):2089-99. Epub 2008 Aug 30.

Department of Bioinformatics and Functional Genomics, Biomedical Computer Vision Group, University of Heidelberg, BIOQUANT, IPMB, Heidelberg, Germany.

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http://dx.doi.org/10.1016/j.bbamcr.2008.08.007DOI Listing
November 2008

Respiratory motion compensation for CT-guided interventions in the liver.

Comput Aided Surg 2008 May;13(3):125-38

Division of Medical and Biological Informatics, German Cancer Research Center, Heidelberg, Germany.

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http://dx.doi.org/10.3109/10929080802091099DOI Listing
May 2008

A model for the self-organization of exit sites in the endoplasmic reticulum.

J Cell Sci 2008 Jan 11;121(Pt 1):55-64. Epub 2007 Dec 11.

Cellular Biophysics Group (BIOMS), German Cancer Research Center, Bioquant Center, Im Neuenheimer Feld 267, D-69120 Heidelberg, Germany.

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http://jcs.biologists.org/cgi/doi/10.1242/jcs.013383
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http://dx.doi.org/10.1242/jcs.013383DOI Listing
January 2008

Quantitative comparison of DNA detection by GFP-lac repressor tagging, fluorescence in situ hybridization and immunostaining.

BMC Biotechnol 2007 Dec 20;7:92. Epub 2007 Dec 20.

University of Heidelberg, BIOQUANT, IPMB, and German Cancer Research Center (DKFZ), Dept. Bioinformatics and FunctionalGenomics, Biomedical Computer Vision Group, Im Neuenheimer Feld 267, 69120 Heidelberg, Germany.

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http://dx.doi.org/10.1186/1472-6750-7-92DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2254608PMC
December 2007

Surveillance of siRNA integrity by FRET imaging.

Nucleic Acids Res 2007 22;35(18):e124. Epub 2007 Sep 22.

Department of Chemistry, Institute for Pharmacy and Molecular Biotechnology (IPMB), University of Heidelberg, Im Neuenheimer Feld 364, D-69120 Heidelberg, Germany.

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http://nar.oxfordjournals.org/content/35/18/e124.full-text-l
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http://nar.oxfordjournals.org/lookup/doi/10.1093/nar/gkm694
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http://dx.doi.org/10.1093/nar/gkm694DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2094076PMC
November 2007

Theoretical limits of localizing 3-D landmarks and features.

Authors:
Karl Rohr

IEEE Trans Biomed Eng 2007 Sep;54(9):1613-20

Computer Vision Group (BMCV), University of Heidelberg, Germany.

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http://dx.doi.org/10.1109/TBME.2007.902589DOI Listing
September 2007

Segmentation and quantification of human vessels using a 3-D cylindrical intensity model.

IEEE Trans Image Process 2007 Aug;16(8):1994-2004

Department of Bioinformatics and Functional Genomics, Biomedical Computer Vision Group, BIOQUANT, and IPMB, University of Heidelberg, D-69120 Heidelberg, Germany.

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http://dx.doi.org/10.1109/tip.2007.901204DOI Listing
August 2007

Fundamental limits in 3D landmark localization.

Authors:
Karl Rohr

Inf Process Med Imaging 2005 ;19:286-98

University of Heidelberg, IPMB, DKFZ Heidelberg, Dept. Intelligent Bioinformatics Systems, Biomedical Computer Vision Group, Im Neuenheimer Feld 580, D-69120 Heidelberg, Germany.

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http://dx.doi.org/10.1007/11505730_24DOI Listing
April 2007

Physics-based elastic image registration using splines and including landmark localization uncertainties.

Med Image Comput Comput Assist Interv 2006 ;9(Pt 2):678-85

University of Heidelberg, IPMB, and DKFZ Heidelberg, Dept. Bioinformatics and Functional Genomics, Biomedical Computer Vision Group Im Neuenheimer Feld 364, 69120 Heidelberg, Germany.

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http://dx.doi.org/10.1007/11866763_83DOI Listing
April 2007

Limits on estimating the width of thin tubular structures in 3D images.

Med Image Comput Comput Assist Interv 2006 ;9(Pt 1):215-22

University of Heidelberg, IPMB, and DKFZ Heidelberg, Dept. Bioinformatics and Functional Genomics, Biomedical Computer Vision Group, Im Neuenheimer Feld 364, 69120 Heidelberg, Germany

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http://dx.doi.org/10.1007/11866565_27DOI Listing
April 2007

Automated analysis of the mitotic phases of human cells in 3D fluorescence microscopy image sequences.

Med Image Comput Comput Assist Interv 2006 ;9(Pt 1):840-8

University of Heidelberg, IPMB, and DKFZ Heidelberg, Dept. Bioinformatics and Functional Genomics, Im Neuenheimer Feld 364, D-69120 Heidelberg, Germany.

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https://pdfs.semanticscholar.org/aacc/749eeb768572007231e7ab
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http://dx.doi.org/10.1007/11866565_103DOI Listing
April 2007

Non-rigid registration of 3D multi-channel microscopy images of cell nuclei.

Med Image Comput Comput Assist Interv 2006 ;9(Pt 1):907-14

Biomedical Computer Vision Group, Dept. Theoretical Bioinformatics, DKFZ Heidelberg, Germany.

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http://link.springer.com/content/pdf/10.1007/11866565_111.pd
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http://dx.doi.org/10.1007/11866565_111DOI Listing
April 2007

Automatic parameter optimization for de-noising MR data.

Med Image Comput Comput Assist Interv 2005 ;8(Pt 2):320-7

Central Institute for Electronics, Research Center Jülich, Germany.

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http://dx.doi.org/10.1007/11566489_40DOI Listing
June 2006

Localization of anatomical point landmarks in 3D medical images by fitting 3D parametric intensity models.

Med Image Anal 2006 Feb;10(1):41-58

University of Heidelberg and DKFZ Heidelberg, Department of Intelligent Bioinformatics Systems, Biomedical Computer Vision Group, Im Neuenheimer Feld 580, 69120 Heidelberg, Germany.

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http://dx.doi.org/10.1016/j.media.2005.02.003DOI Listing
February 2006

An adaptive irregular grid approach for 3D deformable image registration.

Phys Med Biol 2006 Jan 4;51(2):361-77. Epub 2006 Jan 4.

Philips Research Laboratories, Röntgenstrasse 24-26, D-22335 Hamburg, Germany.

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http://dx.doi.org/10.1088/0031-9155/51/2/012DOI Listing
January 2006

Localization of anatomical point landmarks in 3D medical images by fitting 3D parametric intensity models.

Inf Process Med Imaging 2003 Jul;18:76-88

School of Information Technology, Computer Vision & Graphics Group International University in Germany, 76646 Bruchsal.

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http://dx.doi.org/10.1007/978-3-540-45087-0_7DOI Listing
July 2003