Karl Kashofer

Karl Kashofer

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Karl Kashofer

Karl Kashofer

Publications by authors named "Karl Kashofer"

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High-fat diet induces depression-like behaviour in mice associated with changes in microbiome, neuropeptide Y, and brain metabolome.

Nutr Neurosci 2019 Dec 26;22(12):877-893. Epub 2018 Apr 26.

Research Unit of Translational Neurogastroenterology, Division of Pharmacology, Otto Loewi Research Centre, Medical University of Graz, Graz, Austria.

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https://www.tandfonline.com/doi/full/10.1080/1028415X.2018.1
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http://dx.doi.org/10.1080/1028415X.2018.1465713DOI Listing
December 2019

Metaplastic papillary tumour of the fallopian tube, a rare entity - analyzed by NGS.

Histopathology 2019 Dec 7. Epub 2019 Dec 7.

Diagnostic and Research Institute of Pathology, Medical University of Graz, Neue Stiftingtalstraße 6, 8010, Graz, Austria.

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http://dx.doi.org/10.1111/his.14043DOI Listing
December 2019

Atypical goblet cell hyperplasia occurs in CPAM 1, 2, and 3, and is a probable precursor lesion for childhood adenocarcinoma.

Virchows Arch 2019 Dec 19. Epub 2019 Dec 19.

Diagnostic and Research Institute of Pathology, Medical University Graz, Neue Stiftingtalstrasse 6, 8036, Graz, Austria.

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http://dx.doi.org/10.1007/s00428-019-02732-4DOI Listing
December 2019

KIT mutation in a naïve succinate dehydrogenase-deficient gastric GIST.

Genes Chromosomes Cancer 2019 11 10;58(11):798-803. Epub 2019 Jun 10.

Diagnostic and Research Institute of Pathology, Medical University of Graz, Graz, Austria.

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https://onlinelibrary.wiley.com/doi/abs/10.1002/gcc.22768
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http://dx.doi.org/10.1002/gcc.22768DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6771634PMC
November 2019

Steatosis and gut microbiota dysbiosis induced by high-fat diet are reversed by 1-week chow diet administration.

Nutr Res 2019 Nov 23;71:72-88. Epub 2019 Oct 23.

Institute of Pathology, Medical University of Graz, 8010 Graz, Austria. Electronic address:

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http://dx.doi.org/10.1016/j.nutres.2019.09.004DOI Listing
November 2019

Thin variant of high-grade squamous intraepithelial lesion - relationship with high-risk and possibly carcinogenic human papilloma virus subtypes and somatic cancer gene mutations.

Histopathology 2019 Sep 28;75(3):405-412. Epub 2019 Jun 28.

Diagnostic and Research Institute of Pathology, Medical University Graz, Graz, Austria.

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http://dx.doi.org/10.1111/his.13869DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6851765PMC
September 2019

Synergistic and antagonistic interactions between antibiotics and synbiotics in modifying the murine fecal microbiome.

Eur J Nutr 2019 Jul 1. Epub 2019 Jul 1.

Research Unit of Translational Neurogastroenterology, Division of Pharmacology, Otto Loewi Research Center, Medical University of Graz, Universitätsplatz 4, 8010, Graz, Austria.

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http://dx.doi.org/10.1007/s00394-019-02035-zDOI Listing
July 2019

Time series analysis of TP53 gene mutations in recurrent HPV-negative vulvar squamous cell carcinoma.

Mod Pathol 2019 03 5;32(3):415-422. Epub 2018 Oct 5.

Department of Gynecology and Obstetrics, Medical University Graz, Auenbruggerplatz 14, 8036, Graz, Austria.

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http://dx.doi.org/10.1038/s41379-018-0141-4DOI Listing
March 2019

Microbial Evidence in Congenital Pulmonary Airway Malformations of Young Asymptomatic Infants.

J Laparoendosc Adv Surg Tech A 2019 Mar 13. Epub 2019 Mar 13.

1 Department of Pediatric and Adolescent Surgery, Medical University of Graz, Graz, Austria.

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https://www.liebertpub.com/doi/10.1089/lap.2017.0456
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http://dx.doi.org/10.1089/lap.2017.0456DOI Listing
March 2019

Genetic Analysis Using a Gene Panel in 87 Caucasian Patients With Colorectal Cancer: Own Results and Review of Literature.

Anticancer Res 2019 Feb;39(2):847-852

Division of Clinical Oncology, Internal Medicine, Medical University of Graz, Graz, Austria.

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http://dx.doi.org/10.21873/anticanres.13184DOI Listing
February 2019

Gestational diabetes alters microRNA signatures in human feto-placental endothelial cells depending on fetal sex.

Clin Sci (Lond) 2018 11 21;132(22):2437-2449. Epub 2018 Nov 21.

Department of Obstetrics and Gynecology, Medical University of Graz, Graz, Austria

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http://clinsci.org/lookup/doi/10.1042/CS20180825
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http://dx.doi.org/10.1042/CS20180825DOI Listing
November 2018

Role of Next-Generation Sequencing as a Diagnostic Tool for the Evaluation of Bone and Soft-Tissue Tumors.

Pathobiology 2017 18;84(6):323-338. Epub 2017 Aug 18.

Klinisches Institut für Pathologie, Medizinische Universität Graz, Graz, Austria.

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http://dx.doi.org/10.1159/000478662DOI Listing
October 2018

Hirschsprung's Associated Enterocolitis (HAEC) Personalized Treatment with Probiotics Based on Gene Sequencing Analysis of the Fecal Microbiome.

Case Rep Pediatr 2018 14;2018:3292309. Epub 2018 Oct 14.

Department of Paediatric and Adolescent Surgery, Medical University of Graz, Graz, Austria.

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http://dx.doi.org/10.1155/2018/3292309DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6204186PMC
October 2018

Stochastic phenotype switching leads to intratumor heterogeneity in human liver cancer.

Hepatology 2018 09 1;68(3):933-948. Epub 2018 Feb 1.

Institute of Pathology, Medical University of Graz, Graz, Austria.

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http://dx.doi.org/10.1002/hep.29679DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175233PMC
September 2018

Establishment and characterization of an iPSC line from a 35 years old high grade patient with nonalcoholic fatty liver disease (30-40% steatosis) with homozygous wildtype PNPLA3 genotype.

Stem Cell Res 2018 08 25;31:113-116. Epub 2018 Jul 25.

Institute for Stem Cell Research and Regenerative Medicine, Heinrich Heine University, 40225 Düsseldorf, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.scr.2018.07.015DOI Listing
August 2018

Establishment and characterization of an iPSC line from a 58 years old high grade patient with nonalcoholic fatty liver disease (70% steatosis) with homozygous wildtype PNPLA3 genotype.

Stem Cell Res 2018 08 27;31:131-134. Epub 2018 Jul 27.

Institute for Stem Cell Research and Regenerative Medicine, Medical Faculty, Heinrich Heine University, 40225 Düsseldorf, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.scr.2018.07.011DOI Listing
August 2018

Multi-laboratory proficiency testing of clinical cancer genomic profiling by next-generation sequencing.

Pathol Res Pract 2018 Jul 22;214(7):957-963. Epub 2018 May 22.

Department of Pathology and Molecular Pathology, University Hospital Zurich, 8091, Zurich, Switzerland; Senckenberg Institute of Pathology, University Hospital Frankfurt, 60590, Frankfurt, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.prp.2018.05.020DOI Listing
July 2018

The window of opportunities for targeted therapy in BRAFwt/NRASwt/KITwt melanoma: biology and clinical implications of fusion proteins and other mutations.

G Ital Dermatol Venereol 2018 Jun 29;153(3):349-360. Epub 2018 Mar 29.

Department of Dermatology, Medical University of Graz, Graz, Austria.

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http://dx.doi.org/10.23736/S0392-0488.18.05970-9DOI Listing
June 2018

Fast growing melanoma following treatment with vismodegib for locally advanced basal cell carcinomas: report of two cases.

Eur J Cancer 2018 03 16;91:177-179. Epub 2018 Jan 16.

Dermatology Clinic, Hospital Maggiore, University of Trieste, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.ejca.2017.11.031DOI Listing
March 2018

Frequency and clinical impact of preoperative circulating tumor cells in resectable non-metastatic lung adenocarcinomas.

Lung Cancer 2017 11 9;113:152-157. Epub 2017 Oct 9.

Medical University of Graz, Division of Oncology, Department of Internal Medicine, Austria; Medical University of Graz, Research Unit Circulating Tumor Cells and Cancer Stem Cells, Austria.

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https://linkinghub.elsevier.com/retrieve/pii/S01695002173052
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http://dx.doi.org/10.1016/j.lungcan.2017.10.003DOI Listing
November 2017

Neuroblastoma causes alterations of the intestinal microbiome, gut hormones, inflammatory cytokines, and bile acid composition.

Pediatr Blood Cancer 2017 Aug 11;64(8). Epub 2017 Jan 11.

Department of Paediatric and Adolescent Surgery, Medical University of Graz, Graz, Austria.

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http://dx.doi.org/10.1002/pbc.26425DOI Listing
August 2017

Visualization of tumor heterogeneity by in situ padlock probe technology in colorectal cancer.

Histochem Cell Biol 2017 Aug 20;148(2):105-115. Epub 2017 Mar 20.

Institute of Pathology, Medical University of Graz, Graz, Austria.

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http://dx.doi.org/10.1007/s00418-017-1557-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5508037PMC
August 2017

Analysis of full coding sequence of the TP53 gene in invasive vulvar cancers: Implications for therapy.

Gynecol Oncol 2017 08 17;146(2):314-318. Epub 2017 May 17.

Institute of Pathology, Auenbruggerplatz 25, Medical University of Graz, 8036 Graz, Austria. Electronic address:

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http://dx.doi.org/10.1016/j.ygyno.2017.05.018DOI Listing
August 2017

HPV-negative penile squamous cell carcinoma: disruptive mutations in the TP53 gene are common.

Mod Pathol 2017 07 7;30(7):1013-1020. Epub 2017 Apr 7.

Institute of Pathology, Medical University of Graz, Graz, Austria.

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http://dx.doi.org/10.1038/modpathol.2017.26DOI Listing
July 2017

Inferring expressed genes by whole-genome sequencing of plasma DNA.

Nat Genet 2016 10 29;48(10):1273-8. Epub 2016 Aug 29.

Institute of Human Genetics, Medical University of Graz, Graz, Austria.

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http://dx.doi.org/10.1038/ng.3648DOI Listing
October 2016

Cognitive impairment by antibiotic-induced gut dysbiosis: Analysis of gut microbiota-brain communication.

Brain Behav Immun 2016 Aug 23;56:140-55. Epub 2016 Feb 23.

Research Unit of Translational Neurogastroenterology, Institute of Experimental and Clinical Pharmacology, Medical University of Graz, Universitätsplatz 4, 8010 Graz, Austria. Electronic address:

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http://dx.doi.org/10.1016/j.bbi.2016.02.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5014122PMC
August 2016

Mutation Profiling of Usual Ductal Hyperplasia of the Breast Reveals Activating Mutations Predominantly at Different Levels of the PI3K/AKT/mTOR Pathway.

Am J Pathol 2016 Jan;186(1):15-23

Institute of Pathology, Medical University of Graz, Graz, Austria; Department of Pathology, Hospital of the Sisters of Charity, Linz, Austria.

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http://dx.doi.org/10.1016/j.ajpath.2015.09.004DOI Listing
January 2016

Deletion of SPRY4 is a frequent event in secondary acute myeloid leukemia.

Ann Hematol 2015 Nov 25;94(11):1923-4. Epub 2015 Jul 25.

Division of Hematology, Medical University of Graz, Auenbruggerplatz 38, 8036, Graz, Austria.

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http://dx.doi.org/10.1007/s00277-015-2445-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5024751PMC
November 2015

Mutational dichotomy in desmoplastic malignant melanoma corroborated by multigene panel analysis.

Mod Pathol 2015 Jul 13;28(7):895-903. Epub 2015 Mar 13.

Institute of Pathology, Medical University of Graz, Graz, Austria.

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http://dx.doi.org/10.1038/modpathol.2015.39DOI Listing
July 2015

Preexisting TP53 mutation in therapy-related acute myeloid leukemia.

Ann Hematol 2015 Mar 20;94(3):527-9. Epub 2014 Aug 20.

Division of Hematology, Department of Internal Medicine, Medical University of Graz, Auenbruggerplatz 38D, A-8036, Graz, Austria.

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http://dx.doi.org/10.1007/s00277-014-2191-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4317506PMC
March 2015

Comparative analysis of multidimensional, quantitative data.

IEEE Trans Vis Comput Graph 2010 Nov-Dec;16(6):1027-35

Institute for Computer Graphics and Vision, Graz University of Technology.

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http://ieeexplore.ieee.org/document/5613440/
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http://dx.doi.org/10.1109/TVCG.2010.138DOI Listing
December 2010

Humanized large-scale expanded endothelial colony-forming cells function in vitro and in vivo.

Blood 2009 Jun 25;113(26):6716-25. Epub 2009 Mar 25.

Stem Cell Research Unit, and Department of Hematology and Stem Cell Transplantation, University Clinic of Internal Medicine, Medical University of Graz, Auenbrugger Pl 38, Graz, Austria.

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http://www.bloodjournal.org/content/113/26/6716.full.pdf
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http://www.bloodjournal.org/cgi/doi/10.1182/blood-2008-09-18
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http://dx.doi.org/10.1182/blood-2008-09-181362DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2710924PMC
June 2009

Human platelet lysate can replace fetal bovine serum for clinical-scale expansion of functional mesenchymal stromal cells.

Transfusion 2007 Aug;47(8):1436-46

Department of Blood Group Serology and Transfusion Medicine, Division of Hematology and Stem Cell Transplantation, Medical University, Auenbrugger Platz 38, A-8036 Graz, Austria.

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http://doi.wiley.com/10.1111/j.1537-2995.2007.01220.x
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http://dx.doi.org/10.1111/j.1537-2995.2007.01220.xDOI Listing
August 2007

In vivo formation of unstable heterokaryons after liver damage and hematopoietic stem cell/progenitor transplantation.

Stem Cells 2006 Apr 10;24(4):1104-12. Epub 2005 Nov 10.

Hematopoietic Stem Cell Laboratory, Cancer Research UK, London Research Institute, 44 Lincoln's Inn Fields, London, WC2A 3PX, United Kingdom.

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http://dx.doi.org/10.1634/stemcells.2005-0405DOI Listing
April 2006