Publications by authors named "Karl J Lackner"

99Publications

c.451dupT in KLKB1 is common in Nigerians, confirming a higher prevalence of severe prekallikrein deficiency in Africans compared to Europeans.

J Thromb Haemost 2020 Oct 19. Epub 2020 Oct 19.

Center for Thrombosis and Hemostasis (CTH), University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany.

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http://dx.doi.org/10.1111/jth.15137DOI Listing
October 2020

Birth Weight and Diabetic Retinopathy: Results From the Population-Based Gutenberg Health Study (GHS).

Ophthalmic Epidemiol 2020 Sep 29:1-9. Epub 2020 Sep 29.

Department of Ophthalmology, University Medical Center of the Johannes Gutenberg University Mainz , Mainz, Germany.

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http://dx.doi.org/10.1080/09286586.2020.1800753DOI Listing
September 2020

Birthweight and its association with retinal vessel equivalents - Results from the population-based German Gutenberg Health Study.

Acta Ophthalmol 2020 Sep 27. Epub 2020 Sep 27.

Department of Ophthalmology, University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany.

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http://dx.doi.org/10.1111/aos.14637DOI Listing
September 2020

The relationship of ocular geometry with refractive error in normal and low birth weight adults.

J Optom 2020 Sep 23. Epub 2020 Sep 23.

Department of Ophthalmology, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany.

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http://dx.doi.org/10.1016/j.optom.2020.08.004DOI Listing
September 2020

Comprehensive platelet phenotyping supports the role of platelets in the pathogenesis of acute venous thromboembolism - results from clinical observation studies.

EBioMedicine 2020 Oct 10;60:102978. Epub 2020 Sep 10.

Clinical Epidemiology and Systems Medicine, Center for Thrombosis and Hemostasis (CTH), University Medical Center of the Johannes Gutenberg-University Mainz, Germany; Preventive Cardiology and Preventive Medicine, Department of Cardiology, University Medical Center of the Johannes Gutenberg-University Mainz, Germany; DZHK (German Center for Cardiovascular Research), Partner Site RhineMain, Mainz, Germany.

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http://dx.doi.org/10.1016/j.ebiom.2020.102978DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7494681PMC
October 2020

Relation between Tissue Factor Pathway Inhibitor Activity and Cardiovascular Risk Factors and Diseases in a Large Population Sample.

Thromb Haemost 2020 Sep 2. Epub 2020 Sep 2.

Department of Internal Medicine, Laboratory for Clinical Thrombosis and Hemostasis, Cardiovascular Research Institute Maastricht, Maastricht University Medical Center, Maastricht, The Netherlands.

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http://dx.doi.org/10.1055/s-0040-1715897DOI Listing
September 2020

Epidemiologic Analysis of Asteroid Hyalosis and Associations: The Gutenberg Health Study.

Ophthalmology 2020 Jul 9. Epub 2020 Jul 9.

NIHR Biomedical Research Centre at Moorfields Eye Hospital NHS Foundation Trust and UCL Institute of Ophthalmology, London, United Kingdom; Department of Ophthalmology, Centre for Public Health, Institute of Clinical Sciences, School of Medicine, Queen's University Belfast, Belfast, United Kingdom.

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http://dx.doi.org/10.1016/j.ophtha.2020.07.008DOI Listing
July 2020

Gut Microbiota Restricts NETosis in Acute Mesenteric Ischemia-Reperfusion Injury.

Arterioscler Thromb Vasc Biol 2020 09 2;40(9):2279-2292. Epub 2020 Jul 2.

From the Center for Thrombosis and Hemostasis (CTH), University Medical Center of the Johannes Gutenberg University of Mainz (JGU), Germany (S.A., E.W., G.P., H.F., F.B., M.M., F.M., A.G., M.B., M.S., I.B., K.G., K.K., K.J., C.R.).

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http://dx.doi.org/10.1161/ATVBAHA.120.314491DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7484055PMC
September 2020

Prevalence of Strabismus and Its Impact on Vision-Related Quality of Life: Results from the German Population-Based Gutenberg Health Study.

Ophthalmology 2020 Aug 28;127(8):1113-1122. Epub 2020 Feb 28.

Department of Ophthalmology, University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany.

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http://dx.doi.org/10.1016/j.ophtha.2020.02.026DOI Listing
August 2020

Midregional pro atrial natriuretic peptide: a novel important biomarker for noise annoyance-induced cardiovascular morbidity and mortality?

Clin Res Cardiol 2020 Apr 18. Epub 2020 Apr 18.

Center for Cardiology-Cardiology I, University Medical Center of the Johannes Gutenberg-University Mainz, Langenbeckstraße 1, 55131, Mainz, Germany.

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http://dx.doi.org/10.1007/s00392-020-01645-6DOI Listing
April 2020

A non-invasive diagnostic assay for rapid detection and characterization of aberrant mRNA-splicing by nonsense mediated decay inhibition.

Mol Genet Metab 2020 05 19;130(1):27-35. Epub 2020 Mar 19.

Institute of Clinical Chemistry and Laboratory Medicine, University Medical Center Mainz, Langenbeckstr. 1, 55131 Mainz, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.ymgme.2020.03.002DOI Listing
May 2020

Isolated Pulmonary Embolism Is Associated With a High Risk of Arterial Thrombotic Disease: Results From the VTEval Study.

Chest 2020 Jul 23;158(1):341-349. Epub 2020 Mar 23.

Department of Preventive Cardiology and Preventive Medicine, Center for Cardiology, University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany; Center for Thrombosis and Hemostasis (CTH), University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany; German Center for Cardiovascular Research (DZHK), Partner Site Rhine-Main, Mainz, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.chest.2020.01.055DOI Listing
July 2020

Prevalence of myopic maculopathy in the German population: results from the Gutenberg health study.

Br J Ophthalmol 2020 Sep 16;104(9):1254-1259. Epub 2019 Dec 16.

Department of Ophthalmology, University Medical Center Mainz, Mainz University, Mainz, Germany.

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http://dx.doi.org/10.1136/bjophthalmol-2019-315255DOI Listing
September 2020

Low Birth Weight Is Linked to Age-Related Macular Degeneration: Results From the Population-Based Gutenberg Health Study (GHS).

Invest Ophthalmol Vis Sci 2019 11;60(14):4943-4950

Department of Ophthalmology, University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany.

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http://dx.doi.org/10.1167/iovs.19-27964DOI Listing
November 2019

Schirmer test results: are they associated with topical or systemic medication?

Ocul Surf 2020 01 14;18(1):141-147. Epub 2019 Nov 14.

Department of Ophthalmology, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany.

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http://dx.doi.org/10.1016/j.jtos.2019.11.003DOI Listing
January 2020

Characteristics and pathologies of the vitreo-macular interface-results from the Gutenberg Health Study.

Acta Ophthalmol 2020 May 3;98(3):e273-e281. Epub 2019 Nov 3.

Department of Ophthalmology, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany.

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http://dx.doi.org/10.1111/aos.14285DOI Listing
May 2020

Induction of tissue factor expression by anti-β2-glycoprotein I is mediated by tumor necrosis factor α.

J Thromb Thrombolysis 2020 Feb;49(2):228-234

Institute of Clinical Chemistry and Laboratory Medicine, University Medical Center Mainz, Langenbeckstr. 1, 55131, Mainz, Germany.

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http://dx.doi.org/10.1007/s11239-019-01970-2DOI Listing
February 2020

Application of High-Sensitivity Troponin in Suspected Myocardial Infarction.

N Engl J Med 2019 06;380(26):2529-2540

From the University Heart Center Hamburg (J.T.N., R.T., F.O., N.A.S., T.Z., D.W., S.B.), German Center for Cardiovascular Research (DZHK) Partner Site Hamburg-Kiel-Lübeck (J.T.N., N.A.S., T.Z., D.W., S.B.), and the Institute of Clinical Chemistry and Laboratory Medicine, University Medical Center Hamburg-Eppendorf (T.R.), Hamburg, the Department of Cardiology, Heidelberg University Hospital (M.M.-H., H.A.K., E.G.), and DZHK Partner Site Heidelberg-Mannheim (M.M.-H., H.A.K., E.G.), Heidelberg, Cardiology I (T.G., T.M.) and Preventive Cardiology and Preventive Medicine (P.W.), Center for Cardiology, and the Center for Thrombosis and Hemostasis (P.W.), University Medical Center of Johannes Gutenberg University Mainz, and the Institute of Clinical Chemistry and Laboratory Medicine, University Medical Center Mainz (K.J.L.), Mainz, DZHK Partner Site Rhine-Main and the Department of Cardiology, Kerckhoff Heart and Thorax Center, Bad Nauheim (C.L., C.H., T.K.), the Department of Cardiology, Justus Liebig University of Giessen and Marburg, Giessen (C.L., C.H.), the Department of Cardiology, Charité Universitätsmedizin Berlin, Campus Benjamin Franklin, Berlin Institute of Health, and DZHK Partner Site Berlin, Berlin (U.L.), and the Institute of Epidemiology, Helmholtz Zentrum, German Research Center for Environmental Health (B.T., A.P.), and DZHK Partner Site Munich Heart Alliance (A.P.), Munich - all in Germany; the Cardiovascular Research Institute Basel and the Department of Cardiology, University Hospital Basel, University of Basel, Basel, Switzerland (R.T., J.B., T.N., P.B., C.M.); the British Heart Foundation Centre for Cardiovascular Science (A.R.C., A.S.V.S., A.A., N.L.M.) and the Usher Institute of Population Health Sciences and Informatics (A.S.V.S., N.L.M.), University of Edinburgh, Edinburgh, the University of Manchester and Manchester University Foundation Trust, Manchester (N.M., R. Body), U.K. Clinical Research Collaboration for Public Health, Queens University of Belfast, Belfast (F.K.), and the Cardiovascular Epidemiology Unit, Institute of Cardiovascular Research, University of Dundee, Dundee (H.T.-P.) - all in the United Kingdom; the Department of Internal and Emergency Medicine, Lund University, Skåne University Hospital, Lund (A.M., U.E.), the Department of Clinical Sciences, Danderyd University Hospital, Karolinska Institutet, Stockholm (T. Jernberg), the Department of Public Health and Clinical Medicine, and Heart Center, Cardiology, Umeå University, Umeå (S. Söderberg), and the Department of Medical Sciences and Uppsala Clinical Research Center, Uppsala University, Uppsala (B.L.) - all in Sweden; the Department of Medicine, University of Otago Christchurch, and Emergency Department, Christchurch Hospital, Christchurch, New Zealand (J.W.P., R.W.T., M.T.); the Departments of Emergency Medicine (J.G., L.A.C.) and Cardiology (W.P.), Royal Brisbane and Women's Hospital, Herston, QLD, and the Institute of Health and Biomedical Innovation, Queensland University of Technology, Kelvin Grove (J.G., W.P., L.A.C.) - all in Australia; the National Institute for Health and Welfare, Helsinki, Finland (V.S., K.K.); the Department of Epidemiology and Prevention, Istituto di Ricovero e Cura a Carattere Scientifico Neuromed, Pozzilli (L.I.), the Department of Medicine and Surgery, Research Center in Epidemiology and Preventive Medicine, University of Insubria, Varese (L.I., M.M.F., R. Borchini), and the Department of Cardiovascular, Dysmetabolic, and Aging-Associated Diseases, National Institutes of Health, Rome (S.G.) - all in Italy; the Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen (T. Jørgensen), the Research Center for Prevention and Health, Capital Region of Denmark, Glostrup (T. Jørgensen), and the Medical Faculty, Aalborg University, Aalborg (T. Jørgensen) - all in Denmark; the Catalan Department of Health, Barcelona (S. Sans); and the Division of Emergency Medicine (A.W.) and the Department of Pathology and Molecular Medicine (P.A.K.), McMaster University, Hamilton, ON, Canada.

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http://dx.doi.org/10.1056/NEJMoa1803377DOI Listing
June 2019

The Prevalence of Visual Impairment in the Adult Population.

Dtsch Arztebl Int 2019 Apr;116(17):289-295

Department of Ophthalmology, Medical Center, University of Mainz; Department of Ophthalmology, University Hospital Hamburg-Eppendorf (UKE); Preventive Cardiology and Medical Prevention, Cardiology I, Medical Center, University of Mainz; Department of Psychosomatic Medicine and Psychotherapy, Medical Center, University of Mainz; Institute of Medical Biostatistics, Epidemiology and Informatics (IMBEI), Medical Center, University of Mainz; Institute of Clinical Chemistry and Laboratory Medicine, Medical Center, University of Mainz.

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http://dx.doi.org/10.3238/arztebl.2019.0289DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6584831PMC
April 2019

Subtherapeutic Anticoagulation Control under Treatment with Vitamin K-Antagonists-Data from a Specialized Coagulation Service.

Thromb Haemost 2019 Aug 10;119(8):1347-1357. Epub 2019 Jun 10.

Preventive Cardiology and Preventive Medicine, Center for Cardiology, University Medical Center Mainz, Johannes Gutenberg University Mainz, Mainz, Germany.

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http://dx.doi.org/10.1055/s-0039-1692175DOI Listing
August 2019

Choroidal thickness is associated with cardiovascular risk factors and cardiac health: the Gutenberg Health Study.

Clin Res Cardiol 2020 Feb 5;109(2):172-182. Epub 2019 Jun 5.

Preventive Cardiology and Preventive Medicine, Center for Cardiology, University Medical Center, Johannes Gutenberg-University Mainz, Mainz, Germany.

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http://dx.doi.org/10.1007/s00392-019-01498-8DOI Listing
February 2020

Relative Telomere Length and Cardiovascular Risk Factors.

Biomolecules 2019 05 17;9(5). Epub 2019 May 17.

Clinic of General and Interventional Cardiology, University Heart Center Hamburg-Eppendorf, 20246 Hamburg, Germany.

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http://dx.doi.org/10.3390/biom9050192DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6572569PMC
May 2019

Platelet Activation by Antiphospholipid Antibodies Depends on Epitope Specificity and is Prevented by mTOR Inhibitors.

Thromb Haemost 2019 Jul 24;119(7):1147-1153. Epub 2019 Apr 24.

Institute of Clinical Chemistry and Laboratory Medicine, University Medical Center Mainz, Mainz, Germany.

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http://dx.doi.org/10.1055/s-0039-1685453DOI Listing
July 2019

Cardiac biomarkers - 2019.

Authors:
Karl J Lackner

Clin Chem Lab Med 2019 04;57(5):565-566

Institute of Clinical Chemistry and Laboratory Medicine, University Medical Center Mainz, 55101 Mainz, Germany, Phone: +49 6131 177190, Fax: +49 6131 176627.

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http://dx.doi.org/10.1515/cclm-2019-0205DOI Listing
April 2019

Direct oral anticoagulants and vitamin K antagonists are linked to differential profiles of cardiac function and lipid metabolism.

Clin Res Cardiol 2019 Jul 2;108(7):787-796. Epub 2019 Jan 2.

Preventive Cardiology and Preventive Medicine, Center for Cardiology, University Medical Center of the Johannes Gutenberg University Mainz, Langenbeckstr. 1, 55131, Mainz, Germany.

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http://dx.doi.org/10.1007/s00392-018-1408-yDOI Listing
July 2019

Cofactor-Independent Antiphospholipid Antibodies: Implications for Pathogenesis, Diagnosis, and Treatment of Antiphospholipid Syndrome.

Hamostaseologie 2019 Jun 12;39(2):188-194. Epub 2018 Nov 12.

Institute of Clinical Chemistry and Laboratory Medicine, University Medical Center Mainz, Mainz, Germany.

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http://dx.doi.org/10.1055/s-0038-1675355DOI Listing
June 2019

Pathogenesis of antiphospholipid syndrome: recent insights and emerging concepts.

Expert Rev Clin Immunol 2019 02 6;15(2):199-209. Epub 2018 Dec 6.

a Institute of Clinical Chemistry and Laboratory Medicine , University Medical Center of the Johannes Gutenberg University , Mainz , Germany.

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http://dx.doi.org/10.1080/1744666X.2019.1546578DOI Listing
February 2019

Diagnosis and Management of the Antiphospholipid Syndrome.

N Engl J Med 2018 09;379(13):1290

University Medical Center Mainz, Mainz, Germany

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http://dx.doi.org/10.1056/NEJMc1808253DOI Listing
September 2018

Cardiovascular risk factors are important determinants of platelet-dependent thrombin generation in adult survivors of childhood cancer.

Clin Res Cardiol 2019 Apr 22;108(4):438-447. Epub 2018 Sep 22.

Clinical Epidemiology, Center for Thrombosis and Hemostasis (CTH), University Medical Center of the Johannes Gutenberg-University Mainz, Langenbeckstrasse 1, 55131, Mainz, Germany.

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http://dx.doi.org/10.1007/s00392-018-1374-4DOI Listing
April 2019

Relapse Rate in Survivors of Acute Autoimmune Thrombotic Thrombocytopenic Purpura Treated with or without Rituximab.

Thromb Haemost 2018 Oct 20;118(10):1743-1751. Epub 2018 Sep 20.

Department of Hematology, Oncology and Pneumology, University Medical Center of the Johannes Gutenberg University, Mainz, Rheinland-Pfalz, Germany.

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http://dx.doi.org/10.1055/s-0038-1668545DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6202932PMC
October 2018

Adverse Outcome Prediction of Iron Deficiency in Patients with Acute Coronary Syndrome.

Biomolecules 2018 07 20;8(3). Epub 2018 Jul 20.

Department of General and Interventional Cardiology, University Heart Center Hamburg, 20246 Hamburg, Germany.

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http://dx.doi.org/10.3390/biom8030060DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6163749PMC
July 2018

Response to: 'Protective effects of antimalarials in Chinese patients with systemic lupus erythematosus' by Wang .

Ann Rheum Dis 2019 08 26;78(8):e81. Epub 2018 Jun 26.

Institute of Clinical Chemistry and Laboratory Medicine, University Medical Center Mainz, Mainz, Germany.

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http://dx.doi.org/10.1136/annrheumdis-2018-213853DOI Listing
August 2019

Prevalence of glaucoma in Germany: results from the Gutenberg Health Study.

Graefes Arch Clin Exp Ophthalmol 2018 Sep 17;256(9):1695-1702. Epub 2018 May 17.

Department of Ophthalmology, University Medical Center Mainz, Langenbeckstr. 1, 55131, Mainz, Germany.

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http://dx.doi.org/10.1007/s00417-018-4011-zDOI Listing
September 2018

The Theranos saga and the consequences.

Clin Chem Lab Med 2018 08;56(9):1395-1396

Department of Laboratory Medicine, University-Hospital of Padova, Padova, Italy.

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http://dx.doi.org/10.1515/cclm-2018-0392DOI Listing
August 2018

Associations between degree and sub-dimensions of depression and metabolic syndrome (MetS) in the community: results from the Gutenberg Health Study (GHS).

BMC Psychiatry 2018 04 27;18(1):114. Epub 2018 Apr 27.

Department of Psychosomatic Medicine and Psychotherapy, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany.

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http://dx.doi.org/10.1186/s12888-018-1691-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5921368PMC
April 2018

Acute deep vein thrombosis suppresses peripheral T cell effector function.

Br J Haematol 2019 03 25;184(5):847-850. Epub 2018 Mar 25.

Centre for Thrombosis and Hemostasis (CTH), University Medical Centre of the Johannes Gutenberg-University Mainz, Mainz, Germany.

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http://dx.doi.org/10.1111/bjh.15192DOI Listing
March 2019

Corrigendum to "Prognostic Impact of Interleukin-1 Receptor Antagonist in Patients with documented Coronary Artery Disease" [Int. J. Cardiol. 257 (2018) 24-29].

Int J Cardiol 2018 06 21;261:239. Epub 2018 Mar 21.

Department of General and Interventional Cardiology, University Heart Center Hamburg, Hamburg, Germany; German Center of Cardiovascular Research (DZHK), Partner Site Hamburg/Lübeck/Kiel, Hamburg, Germany.

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http://dx.doi.org/10.1016/j.ijcard.2018.03.012DOI Listing
June 2018

Prognostic impact of Interleukin-1 receptor antagonist in patients with documented coronary artery disease.

Int J Cardiol 2018 04 1;257:24-29. Epub 2018 Feb 1.

Department of General and Interventional Cardiology, University Heart Center Hamburg, Hamburg, Germany; German Center of Cardiovascular Research (DZHK), partner site Hamburg/Lübeck/Kiel, Hamburg, Germany.

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http://dx.doi.org/10.1016/j.ijcard.2018.01.055DOI Listing
April 2018

Scientific publishing in the "predatory" era.

Clin Chem Lab Med 2018 04;56(5):683-684

CCLM Editor-in-Chief, Department of Laboratory Medicine, University Hospital of Padova, Padova, Italy.

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http://dx.doi.org/10.1515/cclm-2017-1079DOI Listing
April 2018

Refractive, corneal, and ocular residual astigmatism: distribution in a German population and age dependency-the Gutenberg Health Study.

Graefes Arch Clin Exp Ophthalmol 2018 02 30;256(2):445-446. Epub 2017 Oct 30.

Department of Ophthalmology, University Medical Center Mainz, Langenbeckstr. 1, 55131, Mainz, Germany.

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http://dx.doi.org/10.1007/s00417-017-3822-7DOI Listing
February 2018

Commentary.

Authors:
Karl J Lackner

Clin Chem 2017 10;63(10):1574

Institute of Clinical Chemistry and Laboratory Medicine, and Center for Translational Vascular Biology, University Medical Center Mainz, Germany.

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http://dx.doi.org/10.1373/clinchem.2016.270041DOI Listing
October 2017

High-sensitivity assays for cardiac troponins - continued.

Authors:
Karl J Lackner

Clin Chem Lab Med 2017 10;55(11):1631-1633

.

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http://dx.doi.org/10.1515/cclm-2017-0741DOI Listing
October 2017

Refractive, corneal and ocular residual astigmatism: distribution in a German population and age-dependency - the Gutenberg health study.

Graefes Arch Clin Exp Ophthalmol 2017 Dec 19;255(12):2493-2501. Epub 2017 Aug 19.

Department of Ophthalmology, University Medical Center Mainz, Langenbeckstr. 1, 55131, Mainz, Germany.

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http://dx.doi.org/10.1007/s00417-017-3775-xDOI Listing
December 2017

Transcriptome-Wide Analysis Identifies Novel Associations With Blood Pressure.

Hypertension 2017 10 7;70(4):743-750. Epub 2017 Aug 7.

From the General and Interventional Cardiology, University Heart Center Hamburg, Germany (T.Z., C.M., A.J., M.K., J.T.N., R.B.S., F.O., S.B.); DZHK (German Centre for Cardiovascular Research), Germany (T.Z., C.S., C.M., P.S.W., A.T., A.S., A.K., A.J., M.K., J.T.N., T.K., R.B.S., M.D., T.M., K.J.L., S.B.F., U.L., A.Z., U.V., S.B.); Institute of Human Genetics (K.S., T.M., H.P.), Molecular Epidemiology (C.G., S.W.), and Institute of Epidemiology II (C.G., S.W.), Helmholtz Zentrum München, Germany; Institut für Medizinische Biometrie und Statistik, Universitätsklinikum Schleswig-Holstein, Germany (C.M., A.S., A.Z.); Institute for Translational Genomics and Population Sciences, UCLA Medical Center (S.K., J.I.R., X.G.); Preventive Cardiology and Preventive Medicine (P.S.W.), Institute of Clinical Chemistry and Laboratory Medicine (K.J.L.), and Center for Thrombosis and Hemostasis (P.S.W.), University Medical Center of the Johannes Gutenberg-University Mainz, Germany; Institute for Community Medicine (A.T.) and Department of Internal Medicine B (M.D., S.B.F.), University Medicine Greifswald, Germany; Interfaculty Institute for Genetics and Functional Genomics, University Greifswald, Germany (C.S., T.K., U.V., G.H.); Department of Internal Medicine (D.H., J.D.) and Department of Epidemiology and Prevention (Y.L.), Wake Forest School of Medicine, Winston-Salem, NC; Department of Epidemiology and Prevention, IRCCS Istituto Neurologico Mediterraneo Neuromed, Pozzilli IS, Italy (L.I., S.C.); Department of Cardiology and Pneumology, Charite, Universitätsmedizin Berlin, Germany (A.K., U.L.); National Institute for Health and Welfare, Helsinki, Finland (K.K.); Institute for Clinical Diabetology, German Diabetes Center, Duesseldorf, Germany (M.R., M.C.-K., C.H.); Department of Endocrinology and Diabetology, Medical Faculty Düsseldorf, Germany (M.R.); German Center for Diabetes Research (DZD), Munich, Germany (M.R., S.W., M.C.-K., C.H.); Sorbonne Universités, UPMC, INSERM, UMR_S 1166, ICAN Institute for Cardiometabolism and Nutrition, Paris, France (D.-A.T.); Institute of Human Genetics, Technische Universität München, Germany (T.M., P.W., H.P.); ZIK_FunGene, Universität Greifswald, Germany (U.V., G.H.); and Columbia University Medical Center, New York, NY (W.P.).

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http://dx.doi.org/10.1161/HYPERTENSIONAHA.117.09458DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5997260PMC
October 2017

Urinary neutrophil gelatinase-associated lipocalin and cystatin C compared to the estimated glomerular filtration rate to predict risk in patients with suspected acute myocardial infarction.

Int J Cardiol 2017 Oct 25;245:6-12. Epub 2017 Jul 25.

Division of Cardiology, Department of Internal Medicine III, Goethe University Frankfurt, Germany; German Centre for Cardiovascular Research (DZHK), partner site RheinMain, Frankfurt, Germany; Kerckhoff Heart and Thorax Center, Department of Cardiology, Bad Nauheim, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.ijcard.2017.07.086DOI Listing
October 2017

The SGLT2 inhibitor empagliflozin improves the primary diabetic complications in ZDF rats.

Redox Biol 2017 10 22;13:370-385. Epub 2017 Jun 22.

Center for Cardiology, Cardiology I - Laboratory of Molecular Cardiology, Medical Center of the Johannes Gutenberg University, Mainz, Germany; Boehringer Ingelheim Pharma GmbH & Co. KG, Biberach, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.redox.2017.06.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5491464PMC
October 2017

Relations between lipoprotein(a) concentrations, LPA genetic variants, and the risk of mortality in patients with established coronary heart disease: a molecular and genetic association study.

Authors:
Stephen Zewinger Marcus E Kleber Vinicius Tragante Raymond O McCubrey Amand F Schmidt Kenan Direk Ulrich Laufs Christian Werner Wolfgang Koenig Dietrich Rothenbacher Ute Mons Lutz P Breitling Herrmann Brenner Richard T Jennings Ioannis Petrakis Sarah Triem Mira Klug Alexandra Filips Stefan Blankenberg Christoph Waldeyer Christoph Sinning Renate B Schnabel Karl J Lackner Efthymia Vlachopoulou Ottar Nygård Gard Frodahl Tveitevåg Svingen Eva Ringdal Pedersen Grethe S Tell Juha Sinisalo Markku S Nieminen Reijo Laaksonen Stella Trompet Roelof A J Smit Naveed Sattar J Wouter Jukema Heinrich V Groesdonk Graciela Delgado Tatjana Stojakovic Anna P Pilbrow Vicky A Cameron A Mark Richards Robert N Doughty Yan Gong Rhonda Cooper-DeHoff Julie Johnson Markus Scholz Frank Beutner Joachim Thiery J Gustav Smith Ragnar O Vilmundarson Ruth McPherson Alexandre F R Stewart Sharon Cresci Petra A Lenzini John A Spertus Oliviero Olivieri Domenico Girelli Nicola I Martinelli Andreas Leiherer Christoph H Saely Heinz Drexel Axel Mündlein Peter S Braund Christopher P Nelson Nilesh J Samani Daniel Kofink Imo E Hoefer Gerard Pasterkamp Arshed A Quyyumi Yi-An Ko Jaana A Hartiala Hooman Allayee W H Wilson Tang Stanley L Hazen Niclas Eriksson Claes Held Emil Hagström Lars Wallentin Axel Åkerblom Agneta Siegbahn Igor Karp Christopher Labos Louise Pilote James C Engert James M Brophy George Thanassoulis Peter Bogaty Wojciech Szczeklik Marcin Kaczor Marek Sanak Salim S Virani Christie M Ballantyne Vei-Vei Lee Eric Boerwinkle Michael V Holmes Benjamin D Horne Aroon Hingorani Folkert W Asselbergs Riyaz S Patel Bernhard K Krämer Hubert Scharnagl Danilo Fliser Winfried März Thimoteus Speer

Lancet Diabetes Endocrinol 2017 07 26;5(7):534-543. Epub 2017 May 26.

Department of Internal Medicine IV, Saarland University Hospital, Homburg/Saar, Germany.

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http://dx.doi.org/10.1016/S2213-8587(17)30096-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5651679PMC
July 2017

Retinal vessel metrics: normative data and their use in systemic hypertension: results from the Gutenberg Health Study.

J Hypertens 2017 08;35(8):1635-1645

aDepartment of Ophthalmology bDepartment of Preventive Cardiology and Preventive Medicine, Center for Cardiology I cInstitute of Medical Biostatistics, Epidemiology and Informatics, Division of Biostatistics and Bioinformatics dDepartment of Psychosomatic Medicine and Psychotherapy eInstitute of Clinical Chemistry and Laboratory Medicine fCenter for Thrombosis and Hemostasis, University Medical Center gDZHK (German Center for Cardiovascular Research), Partner Site Rhine Main, Langenbeckstr. 1, Mainz, Germany hDepartment of Ophthalmology, University Hospital Bern, Bern, Switzerland iDardenne Eye Hospital, Bonn-Bad Godesberg, Germany.

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http://dx.doi.org/10.1097/HJH.0000000000001380DOI Listing
August 2017

Large-scale genome-wide analysis identifies genetic variants associated with cardiac structure and function.

Authors:
Philipp S Wild Janine F Felix Arne Schillert Alexander Teumer Ming-Huei Chen Maarten J G Leening Uwe Völker Vera Großmann Jennifer A Brody Marguerite R Irvin Sanjiv J Shah Setia Pramana Wolfgang Lieb Reinhold Schmidt Alice V Stanton Dörthe Malzahn Albert Vernon Smith Johan Sundström Cosetta Minelli Daniela Ruggiero Leo-Pekka Lyytikäinen Daniel Tiller J Gustav Smith Claire Monnereau Marco R Di Tullio Solomon K Musani Alanna C Morrison Tune H Pers Michael Morley Marcus E Kleber Jayashri Aragam Emelia J Benjamin Joshua C Bis Egbert Bisping Ulrich Broeckel Susan Cheng Jaap W Deckers Fabiola Del Greco M Frank Edelmann Myriam Fornage Lude Franke Nele Friedrich Tamara B Harris Edith Hofer Albert Hofman Jie Huang Alun D Hughes Mika Kähönen Knhi Investigators Jochen Kruppa Karl J Lackner Lars Lannfelt Rafael Laskowski Lenore J Launer Margrét Leosdottir Honghuang Lin Cecilia M Lindgren Christina Loley Calum A MacRae Deborah Mascalzoni Jamil Mayet Daniel Medenwald Andrew P Morris Christian Müller Martina Müller-Nurasyid Stefania Nappo Peter M Nilsson Sebastian Nuding Teresa Nutile Annette Peters Arne Pfeufer Diana Pietzner Peter P Pramstaller Olli T Raitakari Kenneth M Rice Fernando Rivadeneira Jerome I Rotter Saku T Ruohonen Ralph L Sacco Tandaw E Samdarshi Helena Schmidt Andrew S P Sharp Denis C Shields Rossella Sorice Nona Sotoodehnia Bruno H Stricker Praveen Surendran Simon Thom Anna M Töglhofer André G Uitterlinden Rolf Wachter Henry Völzke Andreas Ziegler Thomas Münzel Winfried März Thomas P Cappola Joel N Hirschhorn Gary F Mitchell Nicholas L Smith Ervin R Fox Nicole D Dueker Vincent W V Jaddoe Olle Melander Martin Russ Terho Lehtimäki Marina Ciullo Andrew A Hicks Lars Lind Vilmundur Gudnason Burkert Pieske Anthony J Barron Robert Zweiker Heribert Schunkert Erik Ingelsson Kiang Liu Donna K Arnett Bruce M Psaty Stefan Blankenberg Martin G Larson Stephan B Felix Oscar H Franco Tanja Zeller Ramachandran S Vasan Marcus Dörr

J Clin Invest 2017 May 10;127(5):1798-1812. Epub 2017 Apr 10.

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https://www.jci.org/articles/view/84840
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http://dx.doi.org/10.1172/JCI84840DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5409098PMC
May 2017

Endosomal Redox Signaling in the Antiphospholipid Syndrome.

Curr Rheumatol Rep 2017 Apr;19(4):20

Institute of Clinical Chemistry and Laboratory Medicine, University Medical Center Mainz, 55131, Mainz, Germany.

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http://dx.doi.org/10.1007/s11926-017-0647-7DOI Listing
April 2017