Publications by authors named "Karl H Plate"

71Publications

Linking epigenetic signature and metabolic phenotype in IDH mutant and IDH wildtype diffuse glioma.

Neuropathol Appl Neurobiol 2020 Oct 20. Epub 2020 Oct 20.

Neurological Institute (Edinger-Institute), University Hospital, Goethe University Frankfurt am Main, Frankfurt, Germany.

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http://dx.doi.org/10.1111/nan.12669DOI Listing
October 2020

Controversial roles for dexamethasone in glioblastoma - Opportunities for novel vascular targeting therapies.

J Cereb Blood Flow Metab 2019 08 25;39(8):1460-1468. Epub 2019 Jun 25.

1 Institute of Neurology (Edinger Institute), University Hospital, Goethe University, Frankfurt am Main, Germany.

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http://dx.doi.org/10.1177/0271678X19859847DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6681527PMC
August 2019

DNA methylation-based classification of central nervous system tumours.

Authors:
David Capper David T W Jones Martin Sill Volker Hovestadt Daniel Schrimpf Dominik Sturm Christian Koelsche Felix Sahm Lukas Chavez David E Reuss Annekathrin Kratz Annika K Wefers Kristin Huang Kristian W Pajtler Leonille Schweizer Damian Stichel Adriana Olar Nils W Engel Kerstin Lindenberg Patrick N Harter Anne K Braczynski Karl H Plate Hildegard Dohmen Boyan K Garvalov Roland Coras Annett Hölsken Ekkehard Hewer Melanie Bewerunge-Hudler Matthias Schick Roger Fischer Rudi Beschorner Jens Schittenhelm Ori Staszewski Khalida Wani Pascale Varlet Melanie Pages Petra Temming Dietmar Lohmann Florian Selt Hendrik Witt Till Milde Olaf Witt Eleonora Aronica Felice Giangaspero Elisabeth Rushing Wolfram Scheurlen Christoph Geisenberger Fausto J Rodriguez Albert Becker Matthias Preusser Christine Haberler Rolf Bjerkvig Jane Cryan Michael Farrell Martina Deckert Jürgen Hench Stephan Frank Jonathan Serrano Kasthuri Kannan Aristotelis Tsirigos Wolfgang Brück Silvia Hofer Stefanie Brehmer Marcel Seiz-Rosenhagen Daniel Hänggi Volkmar Hans Stephanie Rozsnoki Jordan R Hansford Patricia Kohlhof Bjarne W Kristensen Matt Lechner Beatriz Lopes Christian Mawrin Ralf Ketter Andreas Kulozik Ziad Khatib Frank Heppner Arend Koch Anne Jouvet Catherine Keohane Helmut Mühleisen Wolf Mueller Ute Pohl Marco Prinz Axel Benner Marc Zapatka Nicholas G Gottardo Pablo Hernáiz Driever Christof M Kramm Hermann L Müller Stefan Rutkowski Katja von Hoff Michael C Frühwald Astrid Gnekow Gudrun Fleischhack Stephan Tippelt Gabriele Calaminus Camelia-Maria Monoranu Arie Perry Chris Jones Thomas S Jacques Bernhard Radlwimmer Marco Gessi Torsten Pietsch Johannes Schramm Gabriele Schackert Manfred Westphal Guido Reifenberger Pieter Wesseling Michael Weller Vincent Peter Collins Ingmar Blümcke Martin Bendszus Jürgen Debus Annie Huang Nada Jabado Paul A Northcott Werner Paulus Amar Gajjar Giles W Robinson Michael D Taylor Zane Jaunmuktane Marina Ryzhova Michael Platten Andreas Unterberg Wolfgang Wick Matthias A Karajannis Michel Mittelbronn Till Acker Christian Hartmann Kenneth Aldape Ulrich Schüller Rolf Buslei Peter Lichter Marcel Kool Christel Herold-Mende David W Ellison Martin Hasselblatt Matija Snuderl Sebastian Brandner Andrey Korshunov Andreas von Deimling Stefan M Pfister

Nature 2018 03 14;555(7697):469-474. Epub 2018 Mar 14.

Hopp Children's Cancer Center at the NCT Heidelberg (KiTZ), Heidelberg, Germany.

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http://dx.doi.org/10.1038/nature26000DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6093218PMC
March 2018

Functional morphology of the blood-brain barrier in health and disease.

Acta Neuropathol 2018 03 6;135(3):311-336. Epub 2018 Feb 6.

Department of Medicine, Section of General Pathology, University of Verona, Verona, Italy.

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http://dx.doi.org/10.1007/s00401-018-1815-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6781630PMC
March 2018

Classification of meningiomas-advances and controversies.

Chin Clin Oncol 2017 Jul 4;6(Suppl 1):S2. Epub 2017 Jun 4.

Institute of Neurology (Edinger-Institute), Goethe University Frankfurt, Frankfurt am Main, Germany; German Cancer Consortium (DKTK), Partner site Frankfurt/Mainz, Germany; German Cancer Research Center (DKFZ), Heidelberg, Germany.

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http://dx.doi.org/10.21037/cco.2017.05.02DOI Listing
July 2017

Long Noncoding RNA MANTIS Facilitates Endothelial Angiogenic Function.

Circulation 2017 Jul 28;136(1):65-79. Epub 2017 Mar 28.

From Institute for Cardiovascular Physiology (M.S.L., C.F., I.J., M.J.M., J.E., F.M., R.P.B.), Functional Proteomics, SFB 815 Core Unit, Faculty of Medicine (F.M.R., J.H., I.W.), Institute of Vascular Signalling (J.H.), Institute of Cardiovascular Regeneration (P.H. Y.P., S.U., K.S., R.A.B., S.D.), Department of Neurosurgery (T.M.F.), Pharmazentrum Frankfurt, Institute of General Pharmacology and Toxicology (K.D.), Goethe University, Germany; ECCPS Bioinformatics and Sequencing Facility (J.P., S.G., C.K., M.L.) and Department of Lung Development and Remodeling (C.V., S.S.P.), Max-Planck-Institute for Heart and Lung Research, Bad Nauheim, Germany; Institute of Neurology (K.H.P., M.M., K.D.); Department of Vascular and Endovascular Surgery, Klinikum Rechts der Isar, Technical University Munich, Germany (L.M.); Luxembourg Centre of Neuropathology (M.M.); Laboratoire National de Santé, Dudelange, Luxembourg (M.M.); Luxembourg Centre for Systems Biomedicine, University of Luxembourg, Esch-sur-Alzette (M.M.); NORLUX Neuro-Oncology Laboratory, Department of Oncology, Luxembourg Institute of Health (M.M.); Cardiovascular Innovation Institute, University of Louisville, KY (S.U.); Department of Internal Medicine, Member of the German Center for Lung Research (DZL), Justus-Liebig University, Giessen, Germany (R.T.S., N.W., S.S.P.); Department of Medicine, Duke University and Durham VA Medical Center, NC (F.J.M.); and German Center of Cardiovascular Research (DZHK), Partner Site RheinMain, Frankfurt, Germany (M.S.L., C.F., I.J., J.H., J.E., P.H., F.M., Y.P., K.H.P., K.S., I.W., R.A.B., S.D., R.P.B.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.116.026991DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5491227PMC
July 2017

β-Catenin Is Required for Endothelial Cyp1b1 Regulation Influencing Metabolic Barrier Function.

J Neurosci 2016 08;36(34):8921-35

Institute of Neurology (Edinger-Institute), Goethe-University Frankfurt Medical School, 60528 Frankfurt, Germany, German Center for Cardiovascular Research, Partner Site Rhine-Main, 60528 Frankfurt, Germany,

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http://dx.doi.org/10.1523/JNEUROSCI.0148-16.2016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6601905PMC
August 2016

Brain invasion in otherwise benign meningiomas does not predict tumor recurrence.

Acta Neuropathol 2016 09 27;132(3):479-81. Epub 2016 Jul 27.

Edinger Institute, Institute of Neurology, Goethe University Frankfurt, 60528, Frankfurt am Main, Germany.

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http://dx.doi.org/10.1007/s00401-016-1598-1DOI Listing
September 2016

Decrease of VEGF-A in myeloid cells attenuates glioma progression and prolongs survival in an experimental glioma model.

Neuro Oncol 2016 07 6;18(7):939-49. Epub 2016 Mar 6.

Department of Neurosurgery, Freiburg University Medical School, Freiburg, Germany (N.O., A.W., M.R.M.); Department of Pathology, University of California San Diego, San Diego, California (N.F.); Department of Medicine, Institut de Recherches Cliniques de Montréal, Université de Montréal, Quebec, Canada (J.V.); Department of Radiation Oncology, University Hospital Freiburg, Germany (S.G., G.N.); Department of Neuropathology, Freiburg University Medical School, Freiburg, Germany (S.D.); Department of Pathology, Freiburg University Medical School, Freiburg, Germany (H.-E.S.); Institute of Neurology (Edinger Institute), Frankfurt University Medical School, Frankfurt, Germany (K.H.P).

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https://academic.oup.com/neuro-oncology/article-lookup/doi/1
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http://dx.doi.org/10.1093/neuonc/now005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4896547PMC
July 2016

Differential expression of vascular endothelial growth factor A, its receptors VEGFR-1, -2, and -3 and co-receptors neuropilin-1 and -2 does not predict bevacizumab response in human astrocytomas.

Neuro Oncol 2016 Feb 30;18(2):173-83. Epub 2015 Nov 30.

Institute of Neurology (Edinger Institute), Goethe University, Frankfurt, Germany (P.B., A.-E.B., M.D., P.Z., K.H., L.M., K.H.P., P.N.H., M.Mi.); Department of Neurosurgery, Goethe University, Frankfurt, Germany (K.F., V.S.); Dr. Senckenberg Institute of Neurooncology, University of Frankfurt am Main, Frankfurt am Main, Germany (K.F., O.B., J.P.S.); Department of Neuroradiology, University of Frankfurt am Main, Frankfurt am Main, Germany (E.H.); Department of Neurosurgery, University Hospital, Freiburg, Germany (M.Ma.); Cancer Consortium (DKTK), Heidelberg, Germany (O.B., J.P.S., K.H.P, P.N.H., M.Mi.); German Cancer Research Center (DKFZ), Heidelberg, Germany (O.B., J.P.S., K.H.P., P.N.H., M.Mi.); Department of Pathology, University of Heidelberg, Heidelberg, Germany (B.G.).

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http://dx.doi.org/10.1093/neuonc/nov288DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4724185PMC
February 2016

Extracellular vesicle-mediated transfer of functional RNA in the tumor microenvironment.

Oncoimmunology 2015 Jun 19;4(6):e1008371. Epub 2015 Mar 19.

Institute of Neurology (Edinger Institute); Frankfurt University Medical School; German Cancer Consortium (DKTK); German Cancer Research Center (DKFZ) ; Frankfurt, Heidelberg, Germany.

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http://dx.doi.org/10.1080/2162402X.2015.1008371DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4485784PMC
June 2015

Angiopoietin-2: a multifaceted cytokine that functions in both angiogenesis and inflammation.

Ann N Y Acad Sci 2015 Jul 13;1347:45-51. Epub 2015 Mar 13.

Edinger Institute/Institute of Neurology, Frankfurt University Medical School, Frankfurt, Germany.

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http://dx.doi.org/10.1111/nyas.12726DOI Listing
July 2015

β-Catenin-Gli1 interaction regulates proliferation and tumor growth in medulloblastoma.

Mol Cancer 2015 Feb 3;14:17. Epub 2015 Feb 3.

Institute of Neurology (Edinger-Institute), Johann Wolfgang Goethe-University Frankfurt, Medical School, Heinrich-Hoffmann-Straße 7, 60528, Frankfurt, Germany.

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http://dx.doi.org/10.1186/s12943-015-0294-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4320815PMC
February 2015

Extracellular vesicle-mediated transfer of genetic information between the hematopoietic system and the brain in response to inflammation.

PLoS Biol 2014 Jun 3;12(6):e1001874. Epub 2014 Jun 3.

Institute of Neurology (Edinger Institute), Frankfurt University Medical School Frankfurt, Frankfurt, Germany; German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.

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http://dx.doi.org/10.1371/journal.pbio.1001874DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4043485PMC
June 2014

Confounding factors in diagnostics of MGMT promoter methylation status in glioblastomas in stereotactic biopsies.

Stereotact Funct Neurosurg 2014 24;92(3):129-39. Epub 2014 Apr 24.

Department of Neurosurgery, Goethe University Frankfurt, Frankfurt/Main, Germany.

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http://dx.doi.org/10.1159/000360582DOI Listing
February 2015

Netrin-1 expression is an independent prognostic factor for poor patient survival in brain metastases.

PLoS One 2014 19;9(3):e92311. Epub 2014 Mar 19.

Edinger Institute, Institute of Neurology, University of Frankfurt am Main, Frankfurt am Main, Germany; German Cancer Consortium (DKTK), Heidelberg, Germany; German Cancer Research Center (DKFZ), Heidelberg, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0092311PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3960244PMC
November 2014

Tumour necrosis factor receptor superfamily member 9 (TNFRSF9) is up-regulated in reactive astrocytes in human gliomas.

Neuropathol Appl Neurobiol 2015 Feb;41(2):e56-67

Edinger Institute, Institute of Neurology, Goethe University Frankfurt, Frankfurt am Main, Germany.

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http://dx.doi.org/10.1111/nan.12135DOI Listing
February 2015

Bone marrow chimera experiments to determine the contribution of hematopoietic stem cells to cerebral angiogenesis.

Methods Mol Biol 2014 ;1135:275-88

Department of Neurosurgery, Freiburg University Medical School, Freiburg, Germany.

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http://dx.doi.org/10.1007/978-1-4939-0320-7_23DOI Listing
September 2014

Analysis of cerebral angiogenesis in human glioblastomas.

Methods Mol Biol 2014 ;1135:187-203

Neurological Institute (Edinger Institute), Frankfurt University Medical School, Frankfurt, Germany.

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http://link.springer.com/content/pdf/10.1007%2F978-1-4939-03
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http://link.springer.com/10.1007/978-1-4939-0320-7_16
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http://dx.doi.org/10.1007/978-1-4939-0320-7_16DOI Listing
September 2014

Analysis of angiogenesis in the developing mouse central nervous system.

Methods Mol Biol 2014 ;1135:55-68

Institute of Neurology, Edinger-Institute, Johann Wolfgang Goethe-University Frankfurt Medical School, Frankfurt, Germany.

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http://dx.doi.org/10.1007/978-1-4939-0320-7_5DOI Listing
September 2014

Cerebral angiogenesis during development: who is conducting the orchestra?

Methods Mol Biol 2014 ;1135:3-20

Institute for Stroke and Dementia Research, Klinikum der Universität München, München, Germany.

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http://dx.doi.org/10.1007/978-1-4939-0320-7_1DOI Listing
September 2014

Generation of neuronal progenitor cells in response to tumors in the human brain.

Stem Cells 2014 Jan;32(1):244-57

Institute of Neurology (Edinger Institute), Department of Neurosurgery, Frankfurt University Medical School, Frankfurt, Germany; German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.

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http://doi.wiley.com/10.1002/stem.1581
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http://dx.doi.org/10.1002/stem.1581DOI Listing
January 2014

Brain homeostasis: VEGF receptor 1 and 2-two unequal brothers in mind.

Cell Mol Life Sci 2013 May 12;70(10):1705-25. Epub 2013 Mar 12.

Neuroscience Center, Institute of Neurology (Edinger Institute), Goethe University Medical School, Heinrich-Hoffmann Strasse 7, 60528, Frankfurt, Germany.

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http://dx.doi.org/10.1007/s00018-013-1279-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3632714PMC
May 2013

EGFL7 ligates αvβ3 integrin to enhance vessel formation.

Blood 2013 04 5;121(15):3041-50. Epub 2013 Feb 5.

Molecular Signal Transduction Laboratory at the Institute of Microscopic Anatomy and Neurobiology, Focus Program Translational Neuroscience (FTN), Johannes Gutenberg University School of Medicine, Mainz, Germany.

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http://dx.doi.org/10.1182/blood-2011-11-394882DOI Listing
April 2013

Anti-tissue factor (TF9-10H10) treatment reduces tumor cell invasiveness in a novel migratory glioma model.

Neuropathology 2013 Oct 5;33(5):515-25. Epub 2013 Feb 5.

Edinger Institute, Institute of Neurology, Goethe University Frankfurt, Frankfurt am Main, Germany.

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http://dx.doi.org/10.1111/neup.12018DOI Listing
October 2013

Tumor angiogenesis and anti-angiogenic therapy in malignant gliomas revisited.

Acta Neuropathol 2012 Dec 11;124(6):763-75. Epub 2012 Nov 11.

Institute of Neurology (Edinger Institute), Frankfurt University Medical School, Frankfurt, Germany.

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http://dx.doi.org/10.1007/s00401-012-1066-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3508273PMC
December 2012

Endothelial Wnt/β-catenin signaling inhibits glioma angiogenesis and normalizes tumor blood vessels by inducing PDGF-B expression.

J Exp Med 2012 Aug 20;209(9):1611-27. Epub 2012 Aug 20.

Institute of Neurology (Edinger Institute) and 2 Institute for Cardiovascular Regeneration, Johann Wolfgang Goethe University Frankfurt Medical School, 60590 Frankfurt am Main, Germany.

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http://dx.doi.org/10.1084/jem.20111580DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3428944PMC
August 2012

Angiopoietin-1 mediates inhibition of hypertension-induced release of angiopoietin-2 from endothelial cells.

Cardiovasc Res 2012 Jun 14;94(3):510-8. Epub 2012 Apr 14.

Division of Cardiovascular Physiology, Institute of Physiology and Pathophysiology, University of Heidelberg, Im Neuenheimer Feld 326, 69120 Heidelberg, Germany.

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https://academic.oup.com/cardiovascres/article-lookup/doi/10
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http://dx.doi.org/10.1093/cvr/cvs124DOI Listing
June 2012

Angiopoietin-2 promotes myeloid cell infiltration in a β₂-integrin-dependent manner.

Blood 2011 Nov 25;118(18):5050-9. Epub 2011 Aug 25.

Edinger Institute/Institute of Neurology, Frankfurt University Medical School, Frankfurt, Germany.

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http://dx.doi.org/10.1182/blood-2011-03-343293DOI Listing
November 2011

Angiopoietin-2 regulates gene expression in TIE2-expressing monocytes and augments their inherent proangiogenic functions.

Cancer Res 2010 Jul 8;70(13):5270-80. Epub 2010 Jun 8.

Academic Unit of Inflammation and Tumour Targeting, University of Sheffield Medical School, Sheffield, United Kingdom.

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http://dx.doi.org/10.1158/0008-5472.CAN-10-0012DOI Listing
July 2010

Sonic hedgehog acts as a negative regulator of {beta}-catenin signaling in the adult tongue epithelium.

Am J Pathol 2010 07 27;177(1):404-14. Epub 2010 May 27.

Institute of Neurology (Edinger-Institute), Johann Wolfgang Goethe-University Medical School, Theodor-Stern-Kai 7, 60590 Frankfurt, Germany.

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http://dx.doi.org/10.2353/ajpath.2010.091079DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2893682PMC
July 2010

Differentiation of the brain vasculature: the answer came blowing by the Wnt.

J Angiogenes Res 2010 Jan 14;2. Epub 2010 Jan 14.

Blood-Brain Barrier Signaling Group, Institute of Neurology (Edinger-Institute, Frankfurt University Medical School, Heinrich-Hofmann-Str. 7, 60528 Frankfurt/Main, Germany.

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http://dx.doi.org/10.1186/2040-2384-2-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2820477PMC
January 2010

VEGFR-1 signaling regulates the homing of bone marrow-derived cells in a mouse stroke model.

J Neuropathol Exp Neurol 2010 Feb;69(2):168-75

Walter Brendel Center of Experimental Medicine, Institute of Cardiovascular Physiology, Ludwig-Maximilians University Munich, Munich, Germany.

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http://dx.doi.org/10.1097/NEN.0b013e3181c9c05bDOI Listing
February 2010

VEGFR-1 regulates adult olfactory bulb neurogenesis and migration of neural progenitors in the rostral migratory stream in vivo.

J Neurosci 2009 Jul;29(27):8704-14

Goethe University Medical School, Institute of Neurology (Edinger Institute), Neuroscience Center, 60528 Frankfurt am Main, Germany.

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http://dx.doi.org/10.1523/JNEUROSCI.5527-08.2009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3865485PMC
July 2009

Endothelial progenitor cells do not contribute to tumor endothelium in primary and metastatic tumors.

Int J Cancer 2009 Oct;125(8):1771-7

Tumor Angiogenesis Research Group, Department of Neurosurgery, University of Freiburg Medical School, D-79106 Freiburg, Germany.

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http://dx.doi.org/10.1002/ijc.24605DOI Listing
October 2009

Epidermal growth factor-like domain 7 (EGFL7) modulates Notch signalling and affects neural stem cell renewal.

Nat Cell Biol 2009 07 7;11(7):873-80. Epub 2009 Jun 7.

Institute of Biochemistry II, Johann Wolfgang Goethe University School of Medicine, Frankfurt am Main, Germany.

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http://dx.doi.org/10.1038/ncb1896DOI Listing
July 2009

Brain tumor stem cells.

Recent Results Cancer Res 2009 ;171:241-59

Neurological Institute (Edinger-Institute), Neuroscience Center, Heinrich-Hoffmann-Str. 7, Frankfurt am Main 60528, Germany.

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http://dx.doi.org/10.1007/978-3-540-31206-2_14DOI Listing
June 2009

Angiogenesis after cerebral ischemia.

Acta Neuropathol 2009 May 14;117(5):481-96. Epub 2009 Jan 14.

Institute of Cardiovascular Physiology, Walter Brendel Center of Experimental Medicine, Ludwig-Maximilians University Munich, Marchioninistr. 27, 81377, Munich, Germany.

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http://link.springer.com/10.1007/s00401-009-0483-6
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http://dx.doi.org/10.1007/s00401-009-0483-6DOI Listing
May 2009

Switching of vascular phenotypes within a murine breast cancer model induced by angiopoietin-2.

J Pathol 2009 03;217(4):571-80

Institute of Neurology/Edinger Institute, Frankfurt University Medical School, Frankfurt, Germany.

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http://doi.wiley.com/10.1002/path.2484
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http://dx.doi.org/10.1002/path.2484DOI Listing
March 2009

Flt-1 signaling in macrophages promotes glioma growth in vivo.

Cancer Res 2008 Sep;68(18):7342-51

Tumor Angiogenesis Research Group, Department of Neurosurgery, University of Freiburg, Freiburg, Germany.

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http://dx.doi.org/10.1158/0008-5472.CAN-07-6241DOI Listing
September 2008

Angiopoietin-2 impairs revascularization after limb ischemia.

Circ Res 2007 07 31;101(1):88-96. Epub 2007 May 31.

Institute of Neurology, Frankfurt University Medical School, 60528 Frankfurt, Germany.

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http://dx.doi.org/10.1161/CIRCRESAHA.106.143594DOI Listing
July 2007

Different networks, common growth factors: shared growth factors and receptors of the vascular and the nervous system.

Acta Neuropathol 2007 Jun 10;113(6):607-26. Epub 2007 May 10.

Institute of Neurology (Edinger Institute), Johann Wolfgang Goethe-University, Frankfurt/Main, Germany.

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http://dx.doi.org/10.1007/s00401-007-0228-3DOI Listing
June 2007

Increased generation of neuronal progenitors after ischemic injury in the aged adult human forebrain.

J Neurosci 2006 Dec;26(50):13114-9

Institute of Neurology (Edinger Institute), University of Frankfurt, D-60528 Frankfurt, Germany.

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http://dx.doi.org/10.1523/JNEUROSCI.4667-06.2006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6674966PMC
December 2006

The role of angiopoietins during angiogenesis in gliomas.

Brain Pathol 2005 Oct;15(4):311-7

Institute of Neurology/Edinger Institute, Frankfurt University Medical School, Frankfurt, Germany.

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http://dx.doi.org/10.1111/j.1750-3639.2005.tb00116.xDOI Listing
October 2005

Angiopoietin-1 promotes tumor angiogenesis in a rat glioma model.

Am J Pathol 2004 Nov;165(5):1557-70

Institute of Neurology, University of Frankfurt Medical School, Deutschordenstrasse 46, 60528 Frankfurt am Main, Frankfurt, Germany.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1618662PMC
http://dx.doi.org/10.1016/S0002-9440(10)63413-XDOI Listing
November 2004

Inhibition of solid tumor growth by gene transfer of VEGF receptor-1 mutants.

Int J Cancer 2004 Sep;111(3):348-57

Department of Molecular Cell Biology, Max Planck Institute for Physiological and Clinical Research, Bad Nauheim, Germany.

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http://dx.doi.org/10.1002/ijc.20260DOI Listing
September 2004

Hypoxia and hypoxia inducible factors (HIF) as important regulators of tumor physiology.

Cancer Treat Res 2004 ;117:219-48

Edinger Institute, Neuropathology, Johann-Wolfgang Goethe University, Deutschordenstr. 46, 60528 Frankfurt, Germany.

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http://dx.doi.org/10.1007/978-1-4419-8871-3_14DOI Listing
April 2004

Minor contribution of bone marrow-derived endothelial progenitors to the vascularization of murine gliomas.

Brain Pathol 2003 Oct;13(4):582-97

Department of Neurosurgery, Freiburg University Medical School, Germany.

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http://dx.doi.org/10.1111/j.1750-3639.2003.tb00487.xDOI Listing
October 2003

Role of hypoxia in tumor angiogenesis-molecular and cellular angiogenic crosstalk.

Cell Tissue Res 2003 Oct 29;314(1):145-55. Epub 2003 Jul 29.

Department of Cell and Molecular Biology, Karolinska Institute, Box 285, SE-17177, Stockholm, Sweden.

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http://dx.doi.org/10.1007/s00441-003-0763-8DOI Listing
October 2003

Participation of bone marrow-derived cells in long-term repair processes after experimental stroke.

J Cereb Blood Flow Metab 2003 Jun;23(6):709-17

GSF-Research Center for Environment & Health, Institute for Clinical Molecular Biology and Tumor Genetics, Munich, Germany.

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http://dx.doi.org/10.1097/01.WCB.0000065940.18332.8DDOI Listing
June 2003

A role for hypoxia and hypoxia-inducible transcription factors in tumor physiology.

J Mol Med (Berl) 2002 Sep 21;80(9):562-75. Epub 2002 Jun 21.

Edinger Institute, Johann Wolfgang Goethe University, Deutschordenstrasse 46, 60528 Frankfurt, Germany.

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http://dx.doi.org/10.1007/s00109-002-0355-1DOI Listing
September 2002

Cell type-specific expression of neuropilins in an MCA-occlusion model in mice suggests a potential role in post-ischemic brain remodeling.

J Neuropathol Exp Neurol 2002 Apr;61(4):339-50

Institute of Neurology (Edinger-institute), JWG University, Frankfurt am Main, Germany.

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http://dx.doi.org/10.1093/jnen/61.4.339DOI Listing
April 2002