Karin Pleban

Karin Pleban

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Karin Pleban

Karin Pleban

Publications by authors named "Karin Pleban"

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10Publications

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Conjugation to 4-aminoquinoline improves the anti-trypanosomal activity of Deferiprone-type iron chelators.

Bioorg Med Chem 2013 Feb 27;21(3):805-13. Epub 2012 Nov 27.

Institute of Pharmaceutical Science, School of Biomedical Sciences, King's College London, SE19NH, UK.

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http://dx.doi.org/10.1016/j.bmc.2012.11.009DOI Listing
February 2013

Structure-activity relationships, ligand efficiency, and lipophilic efficiency profiles of benzophenone-type inhibitors of the multidrug transporter P-glycoprotein.

J Med Chem 2012 Apr 27;55(7):3261-73. Epub 2012 Mar 27.

University of Vienna, Department of Medicinal Chemistry, Althanstrasse 14, 1090, Vienna, Austria.

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http://dx.doi.org/10.1021/jm201705fDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3326594PMC
April 2012

Targeting drug-efflux pumps -- a pharmacoinformatic approach.

Acta Biochim Pol 2005 4;52(3):737-40. Epub 2005 Aug 4.

Emerging Focus Pharmacoinformatics, Department of Medicinal Chemistry, University of Vienna, Wien, Austria.

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May 2006

Insights into phenylalanine derivatives recognition of VLA-4 integrin: from a pharmacophoric study to 3D-QSAR and molecular docking analyses.

J Chem Inf Comput Sci 2004 Sep-Oct;44(5):1829-39

Dipartimento di Chimica e Tecnologia del Farmaco, Università di Perugia, via del Liceo 1, 06127 Perugia, Italy.

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http://pubs.acs.org/doi/abs/10.1021/ci049914l
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http://dx.doi.org/10.1021/ci049914lDOI Listing
November 2005

P-glycoprotein substrate binding domains are located at the transmembrane domain/transmembrane domain interfaces: a combined photoaffinity labeling-protein homology modeling approach.

Mol Pharmacol 2005 Feb 27;67(2):365-74. Epub 2004 Oct 27.

Institute of Medical Chemistry, Medical University of Vienna, Waehringerstrasse 10, A-1090 Vienna, Austria.

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http://dx.doi.org/10.1124/mol.104.006973DOI Listing
February 2005

Inhibitors of p-glycoprotein--lead identification and optimisation.

Mini Rev Med Chem 2005 Feb;5(2):153-63

Department of Pharmaceutical Chemistry, University of Vienna, Althanstrasse 14, 1090 Wien, Austria.

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February 2005

Homology model of the multidrug transporter LmrA from Lactococcus lactis.

Bioorg Med Chem Lett 2004 Dec;14(23):5823-6

Department of Pharmaceutical Chemistry, University of Vienna, Althanstrasse 14, A-1090 Wien, Austria.

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http://dx.doi.org/10.1016/j.bmcl.2004.09.040DOI Listing
December 2004

A three-dimensional model for the substrate binding domain of the multidrug ATP binding cassette transporter LmrA.

Mol Pharmacol 2004 Nov 10;66(5):1169-79. Epub 2004 Aug 10.

Institute of Medical Chemistry, Medical University of Vienna, Waehringerstrasse 10, A-1090 Vienna, Austria.

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http://dx.doi.org/10.1124/mol.104.001420DOI Listing
November 2004

Resveratrol analogues as selective cyclooxygenase-2 inhibitors: synthesis and structure-activity relationship.

Bioorg Med Chem 2004 Nov;12(21):5571-8

Institute of Pharmaceutical Chemistry, University of Vienna, Althanstrasse 14, A-1090 Vienna, Austria.

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http://dx.doi.org/10.1016/j.bmc.2004.08.008DOI Listing
November 2004

Intramolecular distribution of hydrophobicity influences pharmacological activity of propafenone-type MDR modulators.

Arch Pharm (Weinheim) 2004 Jun;337(6):328-34

Department of Pharmaceutical Chemistry, University of Vienna, Wien, Austria.

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http://dx.doi.org/10.1002/ardp.200300862DOI Listing
June 2004