Karim Hnia

Karim Hnia

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Karim Hnia

Karim Hnia

Publications by authors named "Karim Hnia"

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Shaping Striated Muscles with Ubiquitin Proteasome System in Health and Disease.

Trends Mol Med 2019 Sep 21;25(9):760-774. Epub 2019 Jun 21.

Institut de Pharmacologie et de Biologie Structurale, IPBS, Université de Toulouse, CNRS, UPS, Toulouse, France. Electronic address:

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http://dx.doi.org/10.1016/j.molmed.2019.05.008DOI Listing
September 2019

The MTM1-UBQLN2-HSP complex mediates degradation of misfolded intermediate filaments in skeletal muscle.

Nat Cell Biol 2018 02 22;20(2):198-210. Epub 2018 Jan 22.

Department of Translational Medicine and Neurogenetics, IGBMC, Illkirch, France.

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http://dx.doi.org/10.1038/s41556-017-0024-9DOI Listing
February 2018

Matrix metalloproteinase 11 protects from diabesity and promotes metabolic switch.

Sci Rep 2016 04 29;6:25140. Epub 2016 Apr 29.

Department of Functional Genomics and Cancer, Institut de Génétique et Biologie Moléculaire et Cellulaire (IGBMC)/ CNRS UMR 7104/ INSERM U 964/ Université de Strasbourg, 1 rue Laurent Fries, 67404 Illkirch, France.

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http://dx.doi.org/10.1038/srep25140DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4850390PMC
April 2016

Desmin in muscle and associated diseases: beyond the structural function.

Cell Tissue Res 2015 Jun 31;360(3):591-608. Epub 2014 Oct 31.

Institut de Génétique et de Biologie Moléculaire et Cellulaire, Illkirch, France,

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http://dx.doi.org/10.1007/s00441-014-2016-4DOI Listing
June 2015

Developmental Alterations in Heart Biomechanics and Skeletal Muscle Function in Desmin Mutants Suggest an Early Pathological Root for Desminopathies.

Cell Rep 2015 Jun 4;11(10):1564-76. Epub 2015 Jun 4.

Institut de Génétique et de Biologie Moléculaire et Cellulaire, 67404 Illkirch, France; Centre National de la Recherche Scientifique, UMR7104, 67404 Illkirch, France; Institut National de la Santé et de la Recherche Médicale, U964, 67404 Illkirch, France; Université de Strasbourg, 67404 Illkirch, France. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2015.05.010DOI Listing
June 2015

N-WASP is required for Amphiphysin-2/BIN1-dependent nuclear positioning and triad organization in skeletal muscle and is involved in the pathophysiology of centronuclear myopathy.

EMBO Mol Med 2014 Nov;6(11):1455-75

Myology Group, UMR S 787 INSERM, Université Pierre et Marie Curie Paris 6, Paris, France Institut de Myologie, Groupe Hospitalier Pitié-Salpêtrière, Paris, France Instituto de Medicina Molecular, Faculdade de Medicina da Universidade de Lisboa, Lisboa, Portugal

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http://dx.doi.org/10.15252/emmm.201404436DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4237471PMC
November 2014

The myotubularin-amphiphysin 2 complex in membrane tubulation and centronuclear myopathies.

EMBO Rep 2013 Oct 6;14(10):907-15. Epub 2013 Aug 6.

1] Department of Translational Medecine and Neurogenetics, Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), 1 Rue Laurent Fries 67404, [2] INSERM, U964, [3] CNRS, UMR7104, [4] Université de Strasbourg, [5] Collège de France, chaire de génétique humaine, Illkirch, France.

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http://embor.embopress.org/cgi/doi/10.1038/embor.2013.119
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http://dx.doi.org/10.1038/embor.2013.119DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3807231PMC
October 2013

Loss of catalytically inactive lipid phosphatase myotubularin-related protein 12 impairs myotubularin stability and promotes centronuclear myopathy in zebrafish.

PLoS Genet 2013 Jun 20;9(6):e1003583. Epub 2013 Jun 20.

Genomics Program and Division of Genetics, The Manton Center for Orphan Disease Research, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1371/journal.pgen.1003583DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3688503PMC
June 2013

Myotubularin phosphoinositide phosphatases in human diseases.

Curr Top Microbiol Immunol 2012 ;362:209-33

Department of Translational Medicine and Neurogenetics, IGBMC, Illkirch, France.

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http://dx.doi.org/10.1007/978-94-007-5025-8_10DOI Listing
April 2013

Myotubularin and PtdIns3P remodel the sarcoplasmic reticulum in muscle in vivo.

J Cell Sci 2013 Apr 26;126(Pt 8):1806-19. Epub 2013 Feb 26.

Department of Translational Medicine, Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), INSERM U964, CNRS UMR7104, Université de Strasbourg, Collège de France, 67404 Illkirch, France.

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http://dx.doi.org/10.1242/jcs.118505DOI Listing
April 2013

Phosphatase-dead myotubularin ameliorates X-linked centronuclear myopathy phenotypes in mice.

PLoS Genet 2012 11;8(10):e1002965. Epub 2012 Oct 11.

Department of Translational Medecine, Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), INSERM U964, CNRS UMR7104, Université de Strasbourg, Collège de France, Illkirch, France.

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http://dx.doi.org/10.1371/journal.pgen.1002965DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3469422PMC
March 2013

Myotubularin phosphoinositide phosphatases: cellular functions and disease pathophysiology.

Trends Mol Med 2012 Jun 11;18(6):317-27. Epub 2012 May 11.

Department of Translational Medicine and Neurogenetics, IGBMC (Institut de Génétique et de Biologie Moléculaire et Cellulaire), Illkirch, France.

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http://dx.doi.org/10.1016/j.molmed.2012.04.004DOI Listing
June 2012

Primary T-tubule and autophagy defects in the phosphoinositide phosphatase Jumpy/MTMR14 knockout mice muscle.

Adv Biol Regul 2012 Jan;52(1):98-107

Department of Translational Medicine and Neurogenetics, IGBMC (Institut de Génétique et de Biologie Moléculaire et Cellulaire), 1, rue Laurent Fries, BP10142, 67404 Illkirch, France.

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http://linkinghub.elsevier.com/retrieve/pii/S006525711100055
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http://dx.doi.org/10.1016/j.advenzreg.2011.09.007DOI Listing
January 2012

[The myotubularin-desmin complex regulates mitochondria dynamics].

Med Sci (Paris) 2011 May 25;27(5):458-60. Epub 2011 May 25.

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http://dx.doi.org/10.1051/medsci/2011275004DOI Listing
May 2011

Defects in amphiphysin 2 (BIN1) and triads in several forms of centronuclear myopathies.

Acta Neuropathol 2011 Feb 7;121(2):253-66. Epub 2010 Oct 7.

Department of Neurobiology and Genetics, Institut de Génétique et de Biologie Moléculaire et Cellulaire, Illkirch, France.

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http://dx.doi.org/10.1007/s00401-010-0754-2DOI Listing
February 2011

Myotubularin controls desmin intermediate filament architecture and mitochondrial dynamics in human and mouse skeletal muscle.

J Clin Invest 2011 Jan 6;121(1):70-85. Epub 2010 Dec 6.

Department of Neurobiology and Genetics, Institut de Génétique et de Biologie Moléculaire et Cellulaire, Illkirch, France.

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http://dx.doi.org/10.1172/JCI44021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3007152PMC
January 2011

Biochemical properties of gastrokine-1 purified from chicken gizzard smooth muscle.

PLoS One 2008 5;3(12):e3854. Epub 2008 Dec 5.

INSERM ERI 25 Muscle et Pathologies, Université Montpellier 1, EA 4202, CHU Arnaud de Villeneuve, Montpellier, France.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0003854PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2588339PMC
January 2009

L-arginine decreases inflammation and modulates the nuclear factor-kappaB/matrix metalloproteinase cascade in mdx muscle fibers.

Am J Pathol 2008 Jun 5;172(6):1509-19. Epub 2008 May 5.

INSERM ERI 25 Muscle et Pathologies, CHU A. de Villeneuve, Université de Montpellier1, EA 4202, 34295 Montpellier Cedex 5, France.

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http://dx.doi.org/10.2353/ajpath.2008.071009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2408412PMC
June 2008

ZZ domain of dystrophin and utrophin: topology and mapping of a beta-dystroglycan interaction site.

Biochem J 2007 Feb;401(3):667-77

Université Montpellier 1, Unité de Formation et de Recherche de Médecine, Laboratoire de Physiologie des Interactions, Institut de Biologie, Boulevard Henri IV, F-34062, France.

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http://dx.doi.org/10.1042/BJ20061051DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1770854PMC
February 2007

Modulation of p38 mitogen-activated protein kinase cascade and metalloproteinase activity in diaphragm muscle in response to free radical scavenger administration in dystrophin-deficient Mdx mice.

Am J Pathol 2007 Feb;170(2):633-43

Institut National de la Santé, et de la Recherche Médicale, Equipe ERI 25, Muscle et Pathologies, Université de Montpellier1, Unité de Formation et de Recherche de Médecine, EA701, 4 Boulevard Henri IV, 34060 Montpellier, France.

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http://dx.doi.org/10.2353/ajpath.2007.060344DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1851881PMC
February 2007

Pathological pattern of Mdx mice diaphragm correlates with gradual expression of the short utrophin isoform Up71.

Biochim Biophys Acta 2006 Mar;1762(3):362-72

Université Montpellier 1, UFR de Médecine, Laboratoire de Physiologie des Interactions, EA 701, Institut de Biologie, Boulevard Henri IV, 34062, Montpellier France

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http://dx.doi.org/10.1016/j.bbadis.2005.11.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1974843PMC
March 2006

alpha7B integrin changes in mdx mouse muscles after L-arginine administration.

FEBS Lett 2005 Feb;579(5):1079-84

EA 701, Muscles et Pathologies Chroniques, Institut de Biologie, Boulevard Henri IV, 34060 Montpellier, France.

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http://dx.doi.org/10.1016/j.febslet.2004.12.081DOI Listing
February 2005