Publications by authors named "Karim Benabdellah"

32Publications

Exosomes: Their Role in Pathogenesis, Diagnosis and Treatment of Diseases.

Cancers (Basel) 2020 Dec 30;13(1). Epub 2020 Dec 30.

GENYO Centre for Genomics and Oncological Research, Genomic Medicine Department, Pfizer/University of Granada/Andalusian Regional Government, Health Sciences Technology Park, Av. de la Illustration 114, 18016 Granada, Spain.

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December 2020

Using Gene Editing Approaches to Fine-Tune the Immune System.

Front Immunol 2020 29;11:570672. Epub 2020 Sep 29.

Genomic Medicine Department, GENYO, Centre for Genomics and Oncological Research, Pfizer-University of Granada (Andalusian Regional Government), Health Sciences Technology Park, Granada, Spain.

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September 2020

Externally-Controlled Systems for Immunotherapy: From Bench to Bedside.

Front Immunol 2020 4;11:2044. Epub 2020 Sep 4.

Gene and Cell Therapy Unit, Genomic Medicine Department, Pfizer-University of Granada-Junta de Andalucía Centre for Genomics and Oncological Research (GENYO), Granada, Spain.

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September 2020

Exosome: A New Player in Translational Nanomedicine.

J Clin Med 2020 Jul 26;9(8). Epub 2020 Jul 26.

Genomic Medicine Department, GENYO, Centre for Genomics and Oncological Research, Pfizer-University of Granada (Andalusian Regional Government), Health Sciences Technology Park, Av. de la Illustration 114, 18016 Granada, Spain.

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July 2020

Development of Cellular Models to Study Efficiency and Safety of Gene Edition by Homologous Directed Recombination Using the CRISPR/Cas9 System.

Cells 2020 06 18;9(6). Epub 2020 Jun 18.

Genomic Medicine Department, GENYO, Centre for Genomics and Oncological Research, Pfizer-University of Granada-Andalusian Regional Government, Parque Tecnológico Ciencias de la Salud, Av. de la Ilustración 114, 18016 Granada, Spain.

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June 2020

Genome-edited adult stem cells: Next-generation advanced therapy medicinal products.

Stem Cells Transl Med 2020 06 6;9(6):674-685. Epub 2020 Mar 6.

Genomic Medicine Department, GENYO, Centre for Genomics and Oncological Research, Pfizer-University of Granada (Andalusian Regional Government), Health Sciences Technology Park, Granada, Spain.

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June 2020

The Genome Encodes Two CTR Copper Transporters That Mediate Cu Import Into the Cytosol and a CTR-Like Protein Likely Involved in Copper Tolerance.

Front Plant Sci 2019 16;10:604. Epub 2019 May 16.

Departamento de Microbiología del Suelo y Sistemas Simbióticos, Estación Experimental del Zaidín, Consejo Superior de Investigaciones Científicas, Granada, Spain.

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May 2019

Stable Genetic Modification of Mesenchymal Stromal Cells Using Lentiviral Vectors.

Methods Mol Biol 2019 ;1937:267-280

Centre for Genomics and Oncological Research (GENYO), Pfizer/University of Granada/Andalusian Regional Government, PTS Granada, Granada, Spain.

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July 2019

The IS2 Element Improves Transcription Efficiency of Integration-Deficient Lentiviral Vector Episomes.

Mol Ther Nucleic Acids 2018 Dec 18;13:16-28. Epub 2018 Aug 18.

Genomic Medicine Department, GENYO, Centre for Genomics and Oncological Research, Pfizer-University of Granada-Andalusian Regional Government, PTS Granada, 18016 Granada, Spain; LentiStem Biotech, GENYO, Avda. de la Ilustración 114, 18016 PTS Granada, Spain. Electronic address:

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December 2018

Lent-On-Plus Lentiviral vectors for conditional expression in human stem cells.

Sci Rep 2016 11 17;6:37289. Epub 2016 Nov 17.

Genomic Medicine Department. GENYO, Centre for Genomics and Oncological Research, Pfizer-University of Granada-Andalusian Regional Goverment, Parque Tecnológico Ciencias de la Salud, Av. de la Ilustración 114, 18016 Granada, Spain.

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November 2016

Biased and Unbiased Methods for the Detection of Off-Target Cleavage by CRISPR/Cas9: An Overview.

Int J Mol Sci 2016 Sep 8;17(9). Epub 2016 Sep 8.

Genomic Medicine Department, GENYO-Centre for Genomics and Oncological Research Pfizer-Universidad de Granada-Junta de Andalucía, Avda de la Ilustración 114, 18007 Granada, Spain.

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September 2016

Characterization of Three New Glutaredoxin Genes in the Arbuscular Mycorrhizal Fungus Rhizophagus irregularis: Putative Role of RiGRX4 and RiGRX5 in Iron Homeostasis.

PLoS One 2016 22;11(2):e0149606. Epub 2016 Feb 22.

Departamento de Microbiología del Suelo y Sistemas Simbióticos, Estación Experimental del Zaidín, Consejo Superior de Investigaciones Científicas, Granada, Spain.

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July 2016

Absence of WASp Enhances Hematopoietic and Megakaryocytic Differentiation in a Human Embryonic Stem Cell Model.

Mol Ther 2016 Feb 27;24(2):342-353. Epub 2015 Oct 27.

Genomic Medicine Department, GENYO, Centre for Genomics and Oncological Research, Pfizer-University of Granada-Andalusian Regional Government, Parque Tecnológico Ciencias de la Salud, Granada, Spain. Electronic address:

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February 2016

A chimeric HS4-SAR insulator (IS2) that prevents silencing and enhances expression of lentiviral vectors in pluripotent stem cells.

PLoS One 2014 6;9(1):e84268. Epub 2014 Jan 6.

Human DNA Variability Department, GENYO - Centre for Genomic and Oncological Research (Pfizer/University of Granada/Andalusian Regional Government), PTS Granada, Granada, Spain.

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September 2014

Use of zinc-finger nucleases to knock out the WAS gene in K562 cells: a human cellular model for Wiskott-Aldrich syndrome.

Dis Model Mech 2013 Mar 11;6(2):544-54. Epub 2013 Jan 11.

Human DNA Variability Department, GENYO, Centre for Genomics and Oncological Research, Pfizer-University of Granada-Andalusian Regional Government, Parque Tecnológico Ciencias de la Salud, Av. de la Ilustracion 114, 18007 Granada, Spain.

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March 2013

Mesenchymal stem cells expressing vasoactive intestinal peptide ameliorate symptoms in a model of chronic multiple sclerosis.

Cell Transplant 2013 ;22(5):839-54

GENYO, Centre for Genomics and Oncological Research, Pfizer-University of Granada-Andalusian Regional Government, Parque Tecnológico Salud (PTS), Granada, Spain.

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December 2013

Specific marking of hESCs-derived hematopoietic lineage by WAS-promoter driven lentiviral vectors.

PLoS One 2012 14;7(6):e39091. Epub 2012 Jun 14.

Human DNA Variability Department, Pfizer-Universidad de Granada-Junta de Andalucía Centre for Genomics and Oncological Research, GENYO, Granada, Spain.

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December 2012