Kari Ann Shirey

Kari Ann Shirey

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Kari Ann Shirey

Kari Ann Shirey

Publications by authors named "Kari Ann Shirey"

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38Publications

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Interferon-β Plays a Detrimental Role in Experimental Traumatic Brain Injury by Enhancing Neuroinflammation That Drives Chronic Neurodegeneration.

J Neurosci 2020 Mar 6;40(11):2357-2370. Epub 2020 Feb 6.

Department of Anesthesiology and Shock, Trauma, and Anesthesiology Research Center, University of Maryland School of Medicine, Baltimore, Maryland 21201.

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http://dx.doi.org/10.1523/JNEUROSCI.2516-19.2020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7083281PMC
March 2020

Early or Late Bacterial Lung Infection Increases Mortality After Traumatic Brain Injury in Male Mice and Chronically Impairs Monocyte Innate Immune Function.

Crit Care Med 2020 Mar 5. Epub 2020 Mar 5.

Department of Anesthesiology and Shock, Trauma and Anesthesiology Research (STAR) Center, University of Maryland School of Medicine, Baltimore, MD.

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http://dx.doi.org/10.1097/CCM.0000000000004273DOI Listing
March 2020

Influenza "Trains" the Host for Enhanced Susceptibility to Secondary Bacterial Infection.

mBio 2019 05 7;10(3). Epub 2019 May 7.

Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, Maryland, USA

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http://dx.doi.org/10.1128/mBio.00810-19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6509193PMC
May 2019

Novel role of gastrin releasing peptide-mediated signaling in the host response to influenza infection.

Mucosal Immunol 2019 01 16;12(1):223-231. Epub 2018 Oct 16.

Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, MD, 21201, USA.

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http://dx.doi.org/10.1038/s41385-018-0081-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6301097PMC
January 2019

Host-based lipid inflammation drives pathogenesis in infection.

Proc Natl Acad Sci U S A 2017 11 6;114(47):12596-12601. Epub 2017 Nov 6.

Department of Microbial Pathogenesis, School of Dentistry, University of Maryland, Baltimore, MD 21201;

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http://dx.doi.org/10.1073/pnas.1712887114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5703311PMC
November 2017

The θ-defensin retrocyclin 101 inhibits TLR4- and TLR2-dependent signaling and protects mice against influenza infection.

J Leukoc Biol 2017 10 20;102(4):1103-1113. Epub 2017 Jul 20.

Department of Microbiology and Immunology, University of Maryland, School of Medicine, Baltimore, Maryland, USA.

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http://dx.doi.org/10.1189/jlb.2A1215-567RRDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5597516PMC
October 2017

Enhanced allergic responsiveness after early childhood infection with respiratory viruses: Are long-lived alternatively activated macrophages the missing link?

Pathog Dis 2016 07 12;74(5). Epub 2016 May 12.

Department of Microbiology and Immunology, University of Maryland School of Medicine, 685 W. Baltimore St., Rm 380, Baltimore, MD 21201, USA.

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http://dx.doi.org/10.1093/femspd/ftw047DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5985486PMC
July 2016

A Decoy Peptide that Disrupts TIRAP Recruitment to TLRs Is Protective in a Murine Model of Influenza.

Cell Rep 2015 Jun 18;11(12):1941-52. Epub 2015 Jun 18.

Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, MD 21201, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2015.05.035DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4490105PMC
June 2015

Agents that increase AAM differentiation blunt RSV-mediated lung pathology.

J Leukoc Biol 2014 Dec 9;96(6):951-5. Epub 2014 Jul 9.

Department of Microbiology and Immunology, University of Maryland, School of Medicine, Baltimore, Maryland, USA;

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http://dx.doi.org/10.1189/jlb.4HI0414-226RDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4226793PMC
December 2014

Nuclear factor κB2 p52 protein has a role in antiviral immunity through IκB kinase epsilon-dependent induction of Sp1 protein and interleukin 15.

J Biol Chem 2013 Aug 19;288(35):25066-75. Epub 2013 Jul 19.

Immunology Research Centre, Trinity Biomedical Sciences Institute, School of Biochemistry and Immunology, Trinity College Dublin, Dublin 2, Ireland.

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http://dx.doi.org/10.1074/jbc.M113.469122DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3757171PMC
August 2013

Transcriptional regulation of murine IL-33 by TLR and non-TLR agonists.

J Immunol 2012 Jul 25;189(1):50-60. Epub 2012 May 25.

Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, MD 21201, USA.

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http://dx.doi.org/10.4049/jimmunol.1003554DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3437667PMC
July 2012

Proteinase-activated receptor 2 activation promotes an anti-inflammatory and alternatively activated phenotype in LPS-stimulated murine macrophages.

Innate Immun 2012 Apr 14;18(2):193-203. Epub 2011 Jan 14.

Department of Microbiology and Immunology, University of Maryland, Baltimore (UMB), School of Medicine, Baltimore, Maryland, USA.

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http://dx.doi.org/10.1177/1753425910395044DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3724520PMC
April 2012

The anti-tumor agent, 5,6-dimethylxanthenone-4-acetic acid (DMXAA), induces IFN-beta-mediated antiviral activity in vitro and in vivo.

J Leukoc Biol 2011 Mar 17;89(3):351-7. Epub 2010 Nov 17.

Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA.

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http://dx.doi.org/10.1189/jlb.0410216DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3040469PMC
March 2011

Phagosomal retention of Francisella tularensis results in TIRAP/Mal-independent TLR2 signaling.

J Leukoc Biol 2010 Feb 4;87(2):275-81. Epub 2009 Nov 4.

Department of Microbiology and Immunology, University of Maryland, Baltimore, Baltimore, MD 21201, USA.

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http://dx.doi.org/10.1189/jlb.0909619DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2812562PMC
February 2010

An essential role for the antiviral endoribonuclease, RNase-L, in antibacterial immunity.

Proc Natl Acad Sci U S A 2008 Dec 15;105(52):20816-21. Epub 2008 Dec 15.

Graduate Program in Molecular Medicine, University of Maryland School of Medicine, Baltimore, MD 21201, USA.

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http://dx.doi.org/10.1073/pnas.0807265105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2634919PMC
December 2008

Type I IL-4Rs selectively activate IRS-2 to induce target gene expression in macrophages.

Sci Signal 2008 Dec 23;1(51):ra17. Epub 2008 Dec 23.

Center for Vascular and Inflammatory Diseases, Marlene and Stewart Greenebaum Cancer Center, University of Maryland School of Medicine, Baltimore, MD 21201, USA.

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http://dx.doi.org/10.1126/scisignal.1164795DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2739727PMC
December 2008

Francisella tularensis live vaccine strain induces macrophage alternative activation as a survival mechanism.

J Immunol 2008 Sep;181(6):4159-67

Department of Microbiology and Immunology, University of Maryland, School of Medicine, Baltimore, MD 21201, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2637804PMC
http://dx.doi.org/10.4049/jimmunol.181.6.4159DOI Listing
September 2008

Toll-like receptor 2-mediated signaling requirements for Francisella tularensis live vaccine strain infection of murine macrophages.

Infect Immun 2007 Aug 21;75(8):4127-37. Epub 2007 May 21.

Department of Microbiology and Immunology, University of Maryland, Baltimore, 660 West Redwood Street, Room 324, Baltimore, MD 21201, USA.

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http://dx.doi.org/10.1128/IAI.01868-06DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1951974PMC
August 2007

Synergistic transcriptional activation of indoleamine dioxygenase by IFN-gamma and tumor necrosis factor-alpha.

J Interferon Cytokine Res 2003 Aug;23(8):413-21

Department of Microbiology, Miami University, Oxford, OH 45056, USA.

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http://dx.doi.org/10.1089/107999003322277829DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1488822PMC
August 2003