Publications by authors named "Karen Seibert"

15Publications

Clinical next-generation sequencing in patients with non-small cell lung cancer.

Authors:
Ian S Hagemann Siddhartha Devarakonda Christina M Lockwood David H Spencer Kalin Guebert Andrew J Bredemeyer Hussam Al-Kateb TuDung T Nguyen Eric J Duncavage Catherine E Cottrell Shashikant Kulkarni Rakesh Nagarajan Karen Seibert Maria Baggstrom Saiama N Waqar John D Pfeifer Daniel Morgensztern Ramaswamy Govindan

Cancer 2015 Feb 24;121(4):631-9. Epub 2014 Oct 24.

Division of Laboratory and Genomic Medicine, Department of Pathology and Immunology, Washington University, St. Louis, Missouri.

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February 2015

Clinical genomicist workstation.

Authors:
Mukesh K Sharma Joshua Phillips Saurabh Agarwal Wesley S Wiggins Savita Shrivastava Sunita B Koul Madhurima Bhattacharjee Caerie D Houchins Raghavendra R Kalakota Bijoy George Rekha R Meyer David H Spencer Christina M Lockwood Tudung T Nguyen Eric J Duncavage Hussam Al-Kateb Catherine E Cottrell Suhasini Godala Raviteja Lokineni Sameer M Sawant Vasudev Chatti Suresh Surampudi Raja Rao Sunkishala Ramakant Darbha Sharath Macharla Jeffrey D Milbrandt Herbert W Virgin Robi D Mitra Richard D Head Shashikant Kulkarni Andrew Bredemeyer John D Pfeifer Karen Seibert Rakesh Nagarajan

AMIA Jt Summits Transl Sci Proc 2013 18;2013:156-7. Epub 2013 Mar 18.

Dept. of Pathology and Immunology, Washington University in St. Louis, St. Louis, MO;

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December 2013

Validation of a next-generation sequencing assay for clinical molecular oncology.

Authors:
Catherine E Cottrell Hussam Al-Kateb Andrew J Bredemeyer Eric J Duncavage David H Spencer Haley J Abel Christina M Lockwood Ian S Hagemann Stephanie M O'Guin Lauren C Burcea Christopher S Sawyer Dayna M Oschwald Jennifer L Stratman Dorie A Sher Mark R Johnson Justin T Brown Paul F Cliften Bijoy George Leslie D McIntosh Savita Shrivastava Tudung T Nguyen Jacqueline E Payton Mark A Watson Seth D Crosby Richard D Head Robi D Mitra Rakesh Nagarajan Shashikant Kulkarni Karen Seibert Herbert W Virgin Jeffrey Milbrandt John D Pfeifer

J Mol Diagn 2014 Jan 6;16(1):89-105. Epub 2013 Nov 6.

Department of Pathology and Immunology, Genomics and Pathology Services, Washington University School of Medicine, St. Louis, Missouri.

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January 2014

The novel benzopyran class of selective cyclooxygenase-2 inhibitors-part I: the first clinical candidate.

Authors:
Jane L Wang Jeffery Carter James R Kiefer Ravi G Kurumbail Jennifer L Pawlitz David Brown Susan J Hartmann Matthew J Graneto Karen Seibert John J Talley

Bioorg Med Chem Lett 2010 Dec 23;20(23):7155-8. Epub 2010 Jul 23.

Pfizer Global Research and Development, Chesterfield, MO 63017, USA.

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December 2010

Evaluation of COX-1/COX-2 selectivity and potency of a new class of COX-2 inhibitors.

Authors:
James Gierse Maureen Nickols Kathleen Leahy James Warner Yan Zhang Luz Cortes-Burgos Jeffery Carter Karen Seibert Jaime Masferrer

Eur J Pharmacol 2008 Jun 6;588(1):93-8. Epub 2008 Apr 6.

Pfizer Global Research and Development, 700 Chesterfield Village Parkway N., Chesterfield, Missouri 63198, United States.

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June 2008

Valdecoxib: assessment of cyclooxygenase-2 potency and selectivity.

Authors:
James K Gierse Yan Zhang William F Hood Mark C Walker Jennifer S Trigg Timothy J Maziasz Carol M Koboldt Jerry L Muhammad Ben S Zweifel Jaime L Masferrer Peter C Isakson Karen Seibert

J Pharmacol Exp Ther 2005 Mar 19;312(3):1206-12. Epub 2004 Oct 19.

Arthritis and Inflammation Pharmacology, Pfizer Research, 700 Chesterfield Parkway West, Chesterfield, MO 63017, USA.

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March 2005

Differential inhibition of fracture healing by non-selective and cyclooxygenase-2 selective non-steroidal anti-inflammatory drugs.

Authors:
Louis C Gerstenfeld Mark Thiede Karen Seibert Cindy Mielke Deborah Phippard Bohus Svagr Dennis Cullinane Thomas A Einhorn

J Orthop Res 2003 Jul;21(4):670-5

Department of Orthopaedic Surgery, Orthopaedic Research Laboratory, Boston University Medical Center, Boston, MA 02118, USA.

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July 2003

Mechanism of inhibition of novel COX-2 inhibitors.

Authors:
James Gierse Ravi Kurumbail Mark Walker Bill Hood Joe Monahan Jennifer Pawlitz Rick Stegeman Anna Stevens Jim Kiefer Carol Koboldt Kirby Moreland Scott Rowlinson Larry Marnett Jennifer Pierce Jeff Carter John Talley Peter Isakson Karen Seibert

Adv Exp Med Biol 2002 ;507:365-9

Monsanto/Searle Discovery Research, Chesterfield, Missouri 63198, USA.

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May 2003

Cyclooxygenase-2 in human pathological disease.

Authors:
Alane Koki Nasir K Khan B Mark Woerner A J Dannenberg Lisa Olson Karen Seibert Dorothy Edwards Madorra Hardy Peter Isakson Jaime L Masferrer

Adv Exp Med Biol 2002 ;507:177-84

Searle/Monsanto Co., 700 Chesterfield Parkway N, St. Louis, MO 63017, USA.

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May 2003

Characterization of celecoxib and valdecoxib binding to cyclooxygenase.

Authors:
William F Hood James K Gierse Peter C Isakson James R Kiefer Ravi G Kurumbail Karen Seibert Joseph B Monahan

Mol Pharmacol 2003 Apr;63(4):870-7

Pharmacia Research and Development, St. Louis, Missouri, USA.

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April 2003

Cloning, expression, and selective inhibition of canine cyclooxygenase-1 and cyclooxygenase-2.

Authors:
James K Gierse Nicholas R Staten Gerald F Casperson Carol M Koboldt Jennifer S Trigg Beverly A Reitz Jennifer L Pierce Karen Seibert

Vet Ther 2002 ;3(3):270-80

Pharmacia Discovery Research, Chesterfield, MO 63198, USA.

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January 2003

Pharmacology of celecoxib in rat brain after kainate administration.

Authors:
Paola Ciceri Yan Zhang Alex F Shaffer Kathleen M Leahy Mark B Woerner Walter G Smith Karen Seibert Peter C Isakson

J Pharmacol Exp Ther 2002 Sep;302(3):846-52

Pharmacia Discovery Research, St. Louis, Missouri, USA.

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September 2002

Cyclooxygenase 2-dependent prostaglandin E2 modulates cartilage proteoglycan degradation in human osteoarthritis explants.

Authors:
Medora M Hardy Karen Seibert Pamela T Manning Mark G Currie B Mark Woerner Dorothy Edwards Alane Koki Catherine S Tripp

Arthritis Rheum 2002 Jul;46(7):1789-803

Arthritis and Inflammation Pharmaclogy, Pharmacia Corporation, St. Louis, Missouri 63017, USA.

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July 2002

Nitric Oxide Activates the Cyclooxygenase Pathway in Inflammation.

Authors:
Daniela Salvemini Karen Seibert Jaime L. Masferrer Steven L. Settle Mark G. Currie Philip Needleman

Am J Ther 1995 Sep;2(9):616-619

G.D. Searle, Monsanto Company, St Louis, 63167, USA.

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September 1995

The Role of Cyclooxygenase-2 in Inflammation.

Authors:
Jaime L. Masferrer Ben S. Zweifel Susan M. Colburn Richard L. Ornberg Daniela Salvemini Peter Isakson Karen Seibert

Am J Ther 1995 Sep;2(9):607-610

Department of Inflammatory Diseases Research G.D. Searle T3G, St. Louis, USA, and Analytical Sciences Center, Monsanto Corporate Research.

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September 1995