Karen L Svenson

Karen L Svenson

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Karen L Svenson

Karen L Svenson

Publications by authors named "Karen L Svenson"

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50Publications

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Cleaning Genotype Data from Diversity Outbred Mice.

G3 (Bethesda) 2019 05 7;9(5):1571-1579. Epub 2019 May 7.

The Jackson Laboratory, Bar Harbor, Maine 04609.

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http://dx.doi.org/10.1534/g3.119.400165DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6505173PMC
May 2019

Recommended housing densities for research mice: filling the gap in data-driven alternatives.

FASEB J 2019 03 6;33(3):3097-3111. Epub 2018 Dec 6.

The Jackson Laboratory, Bar Harbor, Maine, USA.

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http://dx.doi.org/10.1096/fj.201801972RDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6404583PMC
March 2019

Erratum: Author Correction: Identification of genes required for eye development by high-throughput screening of mouse knockouts.

Commun Biol 2019 7;2:97. Epub 2019 Mar 7.

Department of Ophthalmology & Vision Science, School of Medicine, U.C. Davis, Sacramento, CA, 95817, USA.

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http://dx.doi.org/10.1038/s42003-019-0349-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6405960PMC
March 2019

Identification of genetic elements in metabolism by high-throughput mouse phenotyping.

Nat Commun 2018 01 18;9(1):288. Epub 2018 Jan 18.

German Mouse Clinic, Institute of Experimental Genetics, Helmholtz Zentrum München, German Research Center for Environmental Health, Ingolstädter Landstr. 1, 85764, Neuherberg, Germany.

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http://dx.doi.org/10.1038/s41467-017-01995-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5773596PMC
January 2018

Corrigendum: High-throughput discovery of novel developmental phenotypes.

Nature 2017 11 8;551(7680):398. Epub 2017 Nov 8.

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http://dx.doi.org/10.1038/nature24643DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5849394PMC
November 2017

High-throughput discovery of novel developmental phenotypes.

Nature 2016 09 14;537(7621):508-514. Epub 2016 Sep 14.

The Jackson Laboratory, Bar Harbor, Maine 04609, USA.

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http://dx.doi.org/10.1038/nature19356DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5295821PMC
September 2016

Effects of Varied Housing Density on a Hybrid Mouse Strain Followed for 20 Months.

PLoS One 2016 22;11(2):e0149647. Epub 2016 Feb 22.

The Jackson Laboratory, 600 Main Street, Bar Harbor, Maine, 04609, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0149647PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4762697PMC
July 2016

Scaling up phenotyping studies.

Authors:
Karen L Svenson

Nat Biotechnol 2015 Nov;33(11):1150-1

The Jackson Laboratory, Bar Harbor, Maine, USA.

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http://dx.doi.org/10.1038/nbt.3400DOI Listing
November 2015

Diversity Outbred Mice Identify Population-Based Exposure Thresholds and Genetic Factors that Influence Benzene-Induced Genotoxicity.

Environ Health Perspect 2015 Mar 6;123(3):237-45. Epub 2014 Nov 6.

Division of the National Toxicology Program, National Institute of Environmental Health Sciences (NIEHS), National Institutes of Health (NIH), Department of Health and Human Resources (DHHS), Research Triangle Park, North Carolina, USA.

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http://dx.doi.org/10.1289/ehp.1408202DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4348743PMC
March 2015

A multi-megabase copy number gain causes maternal transmission ratio distortion on mouse chromosome 2.

PLoS Genet 2015 Feb 13;11(2):e1004850. Epub 2015 Feb 13.

Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America; Carolina Center for Genome Science, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.

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https://dx.plos.org/10.1371/journal.pgen.1004850
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http://dx.doi.org/10.1371/journal.pgen.1004850DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4334553PMC
February 2015

Diet dominates host genotype in shaping the murine gut microbiota.

Cell Host Microbe 2015 Jan 18;17(1):72-84. Epub 2014 Dec 18.

FAS Center for Systems Biology, Harvard University, 52 Oxford Street, Cambridge, MA 02138, USA; Department of Microbiology and Immunology, Hooper Foundation, University of California, San Francisco, 513 Parnassus Avenue, San Francisco, CA 94143, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S19313128140042
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http://dx.doi.org/10.1016/j.chom.2014.11.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4297240PMC
January 2015

The effect of culling on health and physiology of mouse litters.

Lab Anim 2014 Jul 14;48(3):207-215. Epub 2014 Feb 14.

The Jackson Laboratory, Bar Harbor, Maine, USA

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http://dx.doi.org/10.1177/0023677214521606DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4490120PMC
July 2014

Inflammatory dilated cardiomyopathy in Abcg5-deficient mice.

Toxicol Pathol 2013 Aug 5;41(6):880-92. Epub 2012 Nov 5.

Department of Pathology Microbiology and Immunology, School of Veterinary Medicine, University of California-Davis, CA 95616, USA.

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http://dx.doi.org/10.1177/0192623312466191DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3905339PMC
August 2013

The Diversity Outbred mouse population.

Mamm Genome 2012 Oct 15;23(9-10):713-8. Epub 2012 Aug 15.

The Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609, USA.

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http://dx.doi.org/10.1007/s00335-012-9414-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3524832PMC
October 2012

A general Bayesian approach to analyzing diallel crosses of inbred strains.

Genetics 2012 Feb;190(2):413-35

Department of Genetics and Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, North Carolina 27599-7265, USA.

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http://dx.doi.org/10.1534/genetics.111.132563DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3276624PMC
February 2012

Stochastic variation of transcript abundance in C57BL/6J mice.

BMC Genomics 2011 Mar 30;12:167. Epub 2011 Mar 30.

The Jackson Laboratory, Bar Harbor, Maine 04609, USA.

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http://dx.doi.org/10.1186/1471-2164-12-167DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3082245PMC
March 2011

Novel ENU-induced point mutation in scavenger receptor class B, member 1, results in liver specific loss of SCARB1 protein.

PLoS One 2009 Aug 5;4(8):e6521. Epub 2009 Aug 5.

School of Medicine, Institute for Translational Medicine and Therapeutics, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0006521PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2715880PMC
August 2009

Genetic influence on electrocardiogram time intervals and heart rate in aging mice.

Am J Physiol Heart Circ Physiol 2009 Jun 24;296(6):H1907-13. Epub 2009 Apr 24.

The Jackson Laboratory, Bar Harbor, ME 04609, USA.

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http://dx.doi.org/10.1152/ajpheart.00681.2008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2716104PMC
June 2009

Relationships of dietary fat, body composition, and bone mineral density in inbred mouse strain panels.

Physiol Genomics 2008 Mar 29;33(1):26-32. Epub 2008 Jan 29.

The Jackson Laboratory, Bar Harbor, Maine 04609, USA.

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http://dx.doi.org/10.1152/physiolgenomics.00174.2007DOI Listing
March 2008

Mouse consomic strains: exploiting genetic divergence between Mus m. musculus and Mus m. domesticus subspecies.

Genome Res 2008 Mar 6;18(3):509-15. Epub 2008 Feb 6.

Institute of Molecular Genetics, Department of Mouse Molecular Genetics, Academy of Sciences of the Czech Republic, Prague 142 20, Czech Republic.

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http://dx.doi.org/10.1101/gr.7160508DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2259115PMC
March 2008

The mouse as a model for human biology: a resource guide for complex trait analysis.

Nat Rev Genet 2007 Jan;8(1):58-69

The Jackson Laboratory, 600 Main Street, Bar Harbor, Maine 04609, USA.

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http://www.nature.com/articles/nrg2025
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http://dx.doi.org/10.1038/nrg2025DOI Listing
January 2007

Large-scale, high-throughput screening for coagulation and hematologic phenotypes in mice.

Physiol Genomics 2002 Dec 3;11(3):185-93. Epub 2002 Dec 3.

The Jackson Laboratory, Bar Harbor, Maine 04609, USA.

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http://dx.doi.org/10.1152/physiolgenomics.00077.2002DOI Listing
December 2002