Karen L Kotloff

Karen L Kotloff

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Karen L Kotloff

Publications by authors named "Karen L Kotloff"

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Clinical endpoints for efficacy studies.

Vaccine 2019 Aug 10;37(34):4814-4822. Epub 2019 Apr 10.

Division of Infectious Disease and Tropical Pediatrics, Center for Vaccine Development and Global Health, University of Maryland School of Medicine, Baltimore, MD, USA.

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http://dx.doi.org/10.1016/j.vaccine.2019.03.051DOI Listing
August 2019

Safety and immunogenicity of unadjuvanted subvirion monovalent inactivated influenza H3N2 variant (H3N2v) vaccine in children and adolescents.

Vaccine 2019 Aug 30;37(36):5161-5170. Epub 2019 Jul 30.

Molecular Virology and Microbiology, Baylor College of Medicine, Houston, TX, United States; Medicine, Baylor College of Medicine, Houston, TX, United States.

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http://dx.doi.org/10.1016/j.vaccine.2019.07.085DOI Listing
August 2019

The seasonality of diarrheal pathogens: A retrospective study of seven sites over three years.

PLoS Negl Trop Dis 2019 Aug 15;13(8):e0007211. Epub 2019 Aug 15.

Institute for Disease Modeling, Bellevue, Washington, United States of America.

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http://dx.doi.org/10.1371/journal.pntd.0007211DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6711541PMC
August 2019

Cell mediated immune responses elicited in volunteers following immunization with candidate live oral Salmonella enterica serovar Paratyphi A attenuated vaccine strain CVD 1902.

Clin Immunol 2019 Apr 5;201:61-69. Epub 2019 Mar 5.

Department of Pediatrics, Center for Vaccine Development and Global Health, University of Maryland School of Medicine, Baltimore, MD, USA; Department of Medicine, Center for Vaccine Development and Global Health, University of Maryland School of Medicine, Baltimore, MD, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S15216616193001
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http://dx.doi.org/10.1016/j.clim.2019.03.003DOI Listing
April 2019

Epidemiology, Risk Factors, and Outcomes of Respiratory Syncytial Virus Infections in Newborns in Bamako, Mali.

Clin Infect Dis 2019 Feb 27. Epub 2019 Feb 27.

Center for Vaccine Development and Global Health, University of Maryland School of Medicine, Baltimore, USA.

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http://dx.doi.org/10.1093/cid/ciz157DOI Listing
February 2019

Antibiotic Treatment of Nonsevere Pneumonia With Fast Breathing-Is the Pendulum Swinging?

JAMA Pediatr 2019 Jan;173(1):14-16

Center for Vaccine Development and Global Health, University of Maryland School of Medicine, Baltimore.

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http://archpedi.jamanetwork.com/article.aspx?doi=10.1001/jam
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http://dx.doi.org/10.1001/jamapediatrics.2018.3846DOI Listing
January 2019

Dynamics of antimicrobial resistance in intestinal Escherichia coli from children in community settings in South Asia and sub-Saharan Africa.

Nat Microbiol 2018 09 20;3(9):1063-1073. Epub 2018 Aug 20.

Murdoch Children's Research Institute, Royal Children's Hospital, Parkville, Victoria, Australia.

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http://www.nature.com/articles/s41564-018-0217-4
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http://dx.doi.org/10.1038/s41564-018-0217-4DOI Listing
September 2018

Caregiver and adolescent factors associated with delayed completion of the three-dose human papillomavirus vaccination series.

Vaccine 2018 03 7;36(11):1491-1499. Epub 2018 Feb 7.

Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati Children's Hospital Medical Center, 3333 Burnet Avenue, MLC 4000, Cincinnati, OH 45229, United States. Electronic address:

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http://dx.doi.org/10.1016/j.vaccine.2017.12.060DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6055999PMC
March 2018

T cell mediated immunity induced by the live-attenuated Shigella flexneri 2a vaccine candidate CVD 1208S in humans.

J Transl Med 2018 03 13;16(1):61. Epub 2018 Mar 13.

Department of Medicine, Center for Vaccine Development, University of Maryland School of Medicine, Baltimore, MD, 21201, USA.

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http://dx.doi.org/10.1186/s12967-018-1439-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5851169PMC
March 2018

Shigellosis.

Lancet 2018 02 16;391(10122):801-812. Epub 2017 Dec 16.

Enteric and Diarrheal Diseases Programme, Bill & Melinda Gates Foundation, Seattle, WA, USA.

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http://dx.doi.org/10.1016/S0140-6736(17)33296-8DOI Listing
February 2018

Global burden of diarrheal diseases among children in developing countries: Incidence, etiology, and insights from new molecular diagnostic techniques.

Vaccine 2017 12 29;35(49 Pt A):6783-6789. Epub 2017 Jul 29.

Departments of Pediatrics, Center for Vaccine Development, Institute for Global Health, University of Maryland School of Medicine, Baltimore, MD, USA; Departments of Medicine, Center for Vaccine Development, Institute for Global Health, University of Maryland School of Medicine, Baltimore, MD, USA.

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http://dx.doi.org/10.1016/j.vaccine.2017.07.036DOI Listing
December 2017

The effect of costs on Kenyan households' demand for medical care: why time and distance matter.

Health Policy Plan 2017 Dec;32(10):1397-1406

Division of Foodborne, Waterborne, and Environmental Diseases, Centers of Disease Control and Prevention, Atlanta, GA, USA.

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http://dx.doi.org/10.1093/heapol/czx120DOI Listing
December 2017

Shigella infection in children and adults: a formidable foe.

Authors:
Karen L Kotloff

Lancet Glob Health 2017 12;5(12):e1166-e1167

Centre for Vaccine Development, University of Maryland School of Medicine, Baltimore, MD 21201, USA. Electronic address:

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http://dx.doi.org/10.1016/S2214-109X(17)30431-XDOI Listing
December 2017

Global, regional, and national disease burden estimates of acute lower respiratory infections due to respiratory syncytial virus in young children in 2015: a systematic review and modelling study.

Authors:
Ting Shi David A McAllister Katherine L O'Brien Eric A F Simoes Shabir A Madhi Bradford D Gessner Fernando P Polack Evelyn Balsells Sozinho Acacio Claudia Aguayo Issifou Alassani Asad Ali Martin Antonio Shally Awasthi Juliet O Awori Eduardo Azziz-Baumgartner Henry C Baggett Vicky L Baillie Angel Balmaseda Alfredo Barahona Sudha Basnet Quique Bassat Wilma Basualdo Godfrey Bigogo Louis Bont Robert F Breiman W Abdullah Brooks Shobha Broor Nigel Bruce Dana Bruden Philippe Buchy Stuart Campbell Phyllis Carosone-Link Mandeep Chadha James Chipeta Monidarin Chou Wilfrido Clara Cheryl Cohen Elizabeth de Cuellar Duc-Anh Dang Budragchaagiin Dash-Yandag Maria Deloria-Knoll Mukesh Dherani Tekchheng Eap Bernard E Ebruke Marcela Echavarria Carla Cecília de Freitas Lázaro Emediato Rodrigo A Fasce Daniel R Feikin Luzhao Feng Angela Gentile Aubree Gordon Doli Goswami Sophie Goyet Michelle Groome Natasha Halasa Siddhivinayak Hirve Nusrat Homaira Stephen R C Howie Jorge Jara Imane Jroundi Cissy B Kartasasmita Najwa Khuri-Bulos Karen L Kotloff Anand Krishnan Romina Libster Olga Lopez Marilla G Lucero Florencia Lucion Socorro P Lupisan Debora N Marcone John P McCracken Mario Mejia Jennifer C Moisi Joel M Montgomery David P Moore Cinta Moraleda Jocelyn Moyes Patrick Munywoki Kuswandewi Mutyara Mark P Nicol D James Nokes Pagbajabyn Nymadawa Maria Tereza da Costa Oliveira Histoshi Oshitani Nitin Pandey Gláucia Paranhos-Baccalà Lia N Phillips Valentina Sanchez Picot Mustafizur Rahman Mala Rakoto-Andrianarivelo Zeba A Rasmussen Barbara A Rath Annick Robinson Candice Romero Graciela Russomando Vahid Salimi Pongpun Sawatwong Nienke Scheltema Brunhilde Schweiger J Anthony G Scott Phil Seidenberg Kunling Shen Rosalyn Singleton Viviana Sotomayor Tor A Strand Agustinus Sutanto Mariam Sylla Milagritos D Tapia Somsak Thamthitiwat Elizabeth D Thomas Rafal Tokarz Claudia Turner Marietjie Venter Sunthareeya Waicharoen Jianwei Wang Wanitda Watthanaworawit Lay-Myint Yoshida Hongjie Yu Heather J Zar Harry Campbell Harish Nair

Lancet 2017 Sep 7;390(10098):946-958. Epub 2017 Jul 7.

Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, Scotland, UK; Public Health Foundation of India, New Delhi, India. Electronic address:

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http://dx.doi.org/10.1016/S0140-6736(17)30938-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5592248PMC
September 2017

The Burden and Etiology of Diarrheal Illness in Developing Countries.

Authors:
Karen L Kotloff

Pediatr Clin North Am 2017 08;64(4):799-814

Division of Infectious Disease and Tropical Pediatrics, Center for Vaccine Development, Institute for Global Health, University of Maryland School of Medicine, 685 West Baltimore Street, HSF 480, Baltimore, MD 21201, USA. Electronic address:

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http://dx.doi.org/10.1016/j.pcl.2017.03.006DOI Listing
August 2017

Functional and Antigen-Specific Serum Antibody Levels as Correlates of Protection against Shigellosis in a Controlled Human Challenge Study.

Clin Vaccine Immunol 2017 Feb 6;24(2). Epub 2017 Feb 6.

Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, Maryland, USA

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http://dx.doi.org/10.1128/CVI.00412-16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5299116PMC
February 2017

Shigella Vaccine Development: Finding the Path of Least Resistance.

Clin Vaccine Immunol 2016 Dec 5;23(12):904-907. Epub 2016 Dec 5.

Department of Medicine, University of Maryland School of Medicine, Baltimore, Maryland, USA.

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http://dx.doi.org/10.1128/CVI.00444-16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5139600PMC
December 2016

The Relationship Between Distance to Water Source and Moderate-to-Severe Diarrhea in the Global Enterics Multi-Center Study in Kenya, 2008-2011.

Am J Trop Med Hyg 2016 May 29;94(5):1143-9. Epub 2016 Feb 29.

National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia; Kenya Medical Research Institute/Centers for Disease Control and Prevention, Kisumu, Kenya; Center for Global Health Research, Kenya Medical Research Institute, Kisumu, Kenya; Center for Vaccine Development, School of Medicine, University of Maryland, Baltimore, Maryland; Centers for Disease Control and Prevention, Nairobi, Kenya.

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http://dx.doi.org/10.4269/ajtmh.15-0393DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4856616PMC
May 2016

Persistence of Antibody to Influenza A/H5N1 Vaccine Virus: Impact of AS03 Adjuvant.

Clin Vaccine Immunol 2016 01 11;23(1):73-7. Epub 2015 Nov 11.

Center for Vaccine Development, University of Maryland School of Medicine, Baltimore, Maryland, USA

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http://dx.doi.org/10.1128/CVI.00475-15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4711091PMC
January 2016

Community-acquired diarrhoea in a world with rotavirus vaccine: a glimpse into the future.

Lancet Glob Health 2015 Sep 19;3(9):e510-1. Epub 2015 Jul 19.

Center for Vaccine Development, University of Maryland School of Medicine, Baltimore, MD 21201, USA.

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http://dx.doi.org/10.1016/S2214-109X(15)00052-2DOI Listing
September 2015

Streptococcal pharyngitis in schoolchildren in Bamako, Mali.

Pediatr Infect Dis J 2015 May;34(5):463-8

From the *Division of Infectious Disease and Tropical Pediatrics, Department of Pediatrics and ¶Division of Geographic Medicine, Department of Medicine, Center for Vaccine Development, University of Maryland School of Medicine, Baltimore, Maryland; †Centre pour le Développement des Vaccins-Mali, Bamako, Mali; ‡Department of Pediatrics, University of Virginia, Charlottesville, Virginia; and §University of Tennessee Health Science Center and Veterans Affairs Medical Center Research Service, Memphis, Tennessee.

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http://dx.doi.org/10.1097/INF.0000000000000608DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4400231PMC
May 2015

Gut-Homing Conventional Plasmablasts and CD27(-) Plasmablasts Elicited after a Short Time of Exposure to an Oral Live-Attenuated Shigella Vaccine Candidate in Humans.

Front Immunol 2014 20;5:374. Epub 2014 Aug 20.

Center for Vaccine Development, University of Maryland School of Medicine , Baltimore, MD , USA ; Department of Microbiology and Immunology, University of Maryland School of Medicine , Baltimore, MD , USA ; Department of Pediatrics, University of Maryland School of Medicine , Baltimore, MD , USA.

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http://dx.doi.org/10.3389/fimmu.2014.00374DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4138503PMC
September 2014

Clinical and immune responses to inactivated influenza A(H1N1)pdm09 vaccine in children.

Pediatr Infect Dis J 2014 Aug;33(8):865-71

From the *Division of Infectious Disease and Tropical Pediatrics, Department of Pediatrics, Center for Vaccine Development, University of Maryland School of Medicine, Baltimore, MD; †Department of Pediatrics, Vanderbilt Vaccine Research Program, Vanderbilt University School of Medicine, Nashville, TN; ‡Department of Pediatrics, Pediatric Infectious Diseases Section, Children's Mercy Hospital and Clinics, and the University of Missouri-Kansas City, Kansas City, MO; §Division of Pediatric Infectious Diseases, Department of Pediatrics, University of Washington and Seattle Children's Hospital, Seattle, WA; ¶Department of Pediatrics, Duke Clinical Vaccine Unit, Duke University School of Medicine, Durham, NC; ‖Division of General Pediatrics, Department of Pediatrics, Center for Vaccine Development, University of Maryland School of Medicine, Baltimore, MD; **Department of Medicine, Duke University School of Medicine, Durham, NC; ††Southern Research Institute, Birmingham, AL; and ‡‡EMMES Corp, Department of Vaccines and Infectious Diseases, Rockville, MD.

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http://pdfs.journals.lww.com/pidj/2014/08000/Clinical_and_Im
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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/INF.0000000000000329DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4166548PMC
August 2014

High genotypic diversity among rotavirus strains infecting Gambian children.

Pediatr Infect Dis J 2014 Jan;33 Suppl 1:S69-75

From the *Medical Research Council Unit, Fajara, The Gambia; †Center for Vaccine Development, University of Maryland School of Medicine, Baltimore, MD; and ‡Department of Pediatrics, University of Virginia School of Medicine, Charlottesville, VA.

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http://dx.doi.org/10.1097/INF.0000000000000087DOI Listing
January 2014

Shigella antigen-specific B memory cells are associated with decreased disease severity in subjects challenged with wild-type Shigella flexneri 2a.

Clin Immunol 2013 Jul 26;148(1):35-43. Epub 2013 Mar 26.

Center for Vaccine Development, Department of Pediatrics, University of Maryland School of Medicine, Baltimore, MD, USA.

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http://dx.doi.org/10.1016/j.clim.2013.03.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3679276PMC
July 2013

Progress and pitfalls in Shigella vaccine research.

Nat Rev Gastroenterol Hepatol 2013 Apr 19;10(4):245-55. Epub 2013 Feb 19.

University of Maryland School of Medicine, Center for Vaccine Development, Baltimore, MD 21201, USA.

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http://dx.doi.org/10.1038/nrgastro.2013.12DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3747556PMC
April 2013

Potential coverage of a multivalent M protein-based group A streptococcal vaccine.

Vaccine 2013 Mar 31;31(12):1576-81. Epub 2013 Jan 31.

University of Tennessee Health Science Center, Department of Medicine and Veterans Affairs Medical Center Research Service, Memphis, TN, USA.

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http://dx.doi.org/10.1016/j.vaccine.2013.01.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3593940PMC
March 2013

The Global Enteric Multicenter Study (GEMS): impetus, rationale, and genesis.

Clin Infect Dis 2012 Dec;55 Suppl 4:S215-24

Center for Vaccine Development, University of Maryland School of Medicine, Baltimore, MD 21201, USA.

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https://academic.oup.com/cid/article-lookup/doi/10.1093/cid/
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http://dx.doi.org/10.1093/cid/cis761DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3502311PMC
December 2012

Statistical methods in the Global Enteric Multicenter Study (GEMS).

Clin Infect Dis 2012 Dec;55 Suppl 4:S246-53

Center for Vaccine Development, University of Maryland School of Medicine, 685 W Baltimore St, Baltimore, MD 21201, USA.

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http://dx.doi.org/10.1093/cid/cis788DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3502316PMC
December 2012

Data management and other logistical challenges for the GEMS: the data coordinating center perspective.

Clin Infect Dis 2012 Dec;55 Suppl 4:S254-61

Cooperative Studies Program Coordinating Center, Department of Veterans Affairs, PO Box 1010, Perry Point, MD 21902, USA.

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http://academic.oup.com/cid/article/55/suppl_4/S254/325922/D
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http://dx.doi.org/10.1093/cid/cis755DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3502309PMC
December 2012

Burden of disease from cryptosporidiosis.

Curr Opin Infect Dis 2012 Oct;25(5):555-63

Division of Infectious Diseases and Tropical Pediatrics, Department of Pediatrics, Center for Vaccine Development, University of Maryland School of Medicine, Baltimore, Maryland, USA.

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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/QCO.0b013e328357e569DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4465599PMC
October 2012