Karen L Furie

Karen L Furie

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Karen L Furie

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Anticoagulation After Stroke in Patients With Atrial Fibrillation.

Authors:
Riccardo Altavilla Valeria Caso Fabio Bandini Giancarlo Agnelli Georgios Tsivgoulis Shadi Yaghi Karen L Furie Prasanna Tadi Cecilia Becattini Marialuisa Zedde Azmil H Abdul-Rahim Kennedy R Lees Andrea Alberti Michele Venti Monica Acciarresi Cataldo D'Amore Maria Giulia Mosconi Ludovica Anna Cimini Jessica Fusaro Paolo Bovi Monica Carletti Alberto Rigatelli Manuel Cappellari Jukka Putaala Liisa Tomppo Turgut Tatlisumak Simona Marcheselli Alessandro Pezzini Loris Poli Alessandro Padovani Luca Masotti Vieri Vannucchi Sung-Il Sohn Gianni Lorenzini Rossana Tassi Francesca Guideri Maurizio Acampa Giuseppe Martini George Ntaios George Athanasakis Konstantinos Makaritsis Efstathia Karagkiozi Konstantinos Vadikolias Chrysoula Liantinioti Maria Chondrogianni Nicola Mumoli Domenico Consoli Franco Galati Simona Sacco Antonio Carolei Cindy Tiseo Francesco Corea Walter Ageno Marta Bellesini Giorgio Silvestrelli Alfonso Ciccone Alessia Lanari Umberto Scoditti Licia Denti Michelangelo Mancuso Miriam Maccarrone Leonardo Ulivi Giovanni Orlandi Nicola Giannini Gino Gialdini Tiziana Tassinari Maria Luisa De Lodovici Giorgio Bono Christina Rueckert Antonio Baldi Sebastiano D'Anna Danilo Toni Federica Letteri Martina Giuntini Enrico Maria Lotti Yuriy Flomin Alessio Pieroni Odysseas Kargiotis Theodore Karapanayiotides Serena Monaco Mario Maimone Baronello Laszló Csiba Lilla Szabó Alberto Chiti Elisa Giorli Massimo Del Sette Davide Imberti Dorjan Zabzuni Boris Doronin Vera Volodina Patrik Michel Peter Vanacker Kristian Barlinn Lars-Peder Pallesen Jessica Barlinn Dirk Deleu Gayane Melikyan Faisal Ibrahim Naveed Akhtar Vanessa Gourbali Maurizio Paciaroni

Stroke 2019 Aug 21;50(8):2093-2100. Epub 2019 Jun 21.

From the Stroke Unit and Division of Cardiovascular Medicine, University of Perugia, Italy (R.A., V.C., G.A., C.B., A.A., M.V., M.A., C.D., M.G.M., L.A.C., J.F., M.P.).

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http://dx.doi.org/10.1161/STROKEAHA.118.022856DOI Listing
August 2019

Causes and Risk Factors of Cerebral Ischemic Events in Patients With Atrial Fibrillation Treated With Non-Vitamin K Antagonist Oral Anticoagulants for Stroke Prevention.

Authors:
Maurizio Paciaroni Giancarlo Agnelli Valeria Caso Giorgio Silvestrelli David Julian Seiffge Stefan Engelter Gian Marco De Marchis Alexandros Polymeris Maria Luisa Zedde Shadi Yaghi Patrik Michel Ashraf Eskandari Kateryna Antonenko Sung-Il Sohn Manuel Cappellari Tiziana Tassinari Rossana Tassi Luca Masotti Aristeidis H Katsanos Sotirios Giannopoulos Monica Acciarresi Andrea Alberti Michele Venti Maria Giulia Mosconi Maria Cristina Vedovati Patrizia Pierini Michela Giustozzi Enrico Maria Lotti George Ntaios Odysseas Kargiotis Serena Monaco Piergiorgio Lochner Fabio Bandini Chrysoula Liantinioti Lina Palaiodimou Azmil H Abdul-Rahim Kennedy Lees Michelangelo Mancuso Leonardo Pantoni Silvia Rosa Pierluigi Bertora Silvia Galliazzo Walter Ageno Elisabetta Toso Filippo Angelini Alberto Chiti Giovanni Orlandi Licia Denti Yuriy Flomin Simona Marcheselli Nicola Mumoli Alexandra Rimoldi Elena Verrengia Erika Schirinzi Massimo Del Sette Panagiotis Papamichalis Apostolos Komnos Nemanja Popovic Marija Zarkov Alessandro Rocco Marina Diomedi Elisa Giorli Alfonso Ciccone Brian C Mac Grory Karen L Furie Bruno Bonetti Valentina Saia Francesca Guideri Maurizio Acampa Giuseppe Martini Elisa Grifoni Marina Padroni Efstathia Karagkiozi Kalliopi Perlepe Konstantinos Makaritsis Marina Mannino Miriam Maccarrone Leonardo Ulivi Nicola Giannini Elena Ferrari Alessandro Pezzini Boris Doronin Vera Volodina Antonio Baldi Cataldo D'Amore Dirk Deleu Francesco Corea Jukka Putaala Paola Santalucia Katiuscia Nardi Angela Risitano Danilo Toni Georgios Tsivgoulis

Stroke 2019 Aug 25;50(8):2168-2174. Epub 2019 Jun 25.

Second Department of Neurology, Attikon Hospital, National and Kapodistrian University of Athens, School of Medicine, Greece (C.L., L.P., G.T.).

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http://dx.doi.org/10.1161/STROKEAHA.119.025350DOI Listing
August 2019

Sex Differences in Hypertension and Stroke Risk in the REGARDS Study.

Hypertension 2019 Aug 13:HYPERTENSIONAHA11912729. Epub 2019 Aug 13.

Department of Epidemiology, University of Alabama at Birmingham (V.H.).

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http://dx.doi.org/10.1161/HYPERTENSIONAHA.119.12729DOI Listing
August 2019

2019 AHA/ACC/HRS Focused Update of the 2014 AHA/ACC/HRS Guideline for the Management of Patients With Atrial Fibrillation: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines and the Heart Rhythm Society in Collaboration With the Society of Thoracic Surgeons.

Circulation 2019 Jul 28;140(2):e125-e151. Epub 2019 Jan 28.

Writing group members are required to recuse themselves from voting on sections to which their specific relationships with industry may apply; see Appendix 1 for detailed information. †HRS Representative. ‡ACC/AHA Task Force on Clinical Practice Guidelines Liaison. §STS Representative. ‖ACC/AHA Representative. ¶ACC/AHA Task Force on Performance Measures Representative.

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http://dx.doi.org/10.1161/CIR.0000000000000665DOI Listing
July 2019

Emphysema: A Potential Risk Factor for Subarachnoid Hemorrhage and Ruptured Aortic Aneurysm

Stroke 2019 04;50(4):992-994

Clinical and Translational Neuroscience Unit, Feil Family Brain and Mind Research Institute (A.E.M., J.E.B., H.K.), Weill Cornell Medicine, New York, NY.

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http://dx.doi.org/10.1161/STROKEAHA.118.024660DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6433532PMC
April 2019

Sex differences in 90-day outcomes after mechanical thrombectomy for acute ischemic stroke.

J Neurointerv Surg 2019 Mar 10;11(3):221-225. Epub 2018 Aug 10.

Department of Neurology, Alpert Medical School of Brown University, Providence, Rhode Island, USA.

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http://jnis.bmj.com/lookup/doi/10.1136/neurintsurg-2018-0140
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http://dx.doi.org/10.1136/neurintsurg-2018-014050DOI Listing
March 2019

Early recurrence in paroxysmal versus sustained atrial fibrillation in patients with acute ischaemic stroke.

Authors:
Maurizio Paciaroni Filippo Angelini Giancarlo Agnelli Georgios Tsivgoulis Karen L Furie Prasanna Tadi Cecilia Becattini Nicola Falocci Marialuisa Zedde Azmil H Abdul-Rahim Kennedy R Lees Andrea Alberti Michele Venti Monica Acciarresi Riccardo Altavilla Cataldo D'Amore Maria G Mosconi Ludovica A Cimini Paolo Bovi Monica Carletti Alberto Rigatelli Manuel Cappellari Jukka Putaala Liisa Tomppo Turgut Tatlisumak Fabio Bandini Simona Marcheselli Alessandro Pezzini Loris Poli Alessandro Padovani Luca Masotti Vieri Vannucchi Sung-Il Sohn Gianni Lorenzini Rossana Tassi Francesca Guideri Maurizio Acampa Giuseppe Martini George Ntaios Efstathia Karagkiozi George Athanasakis Kostantinos Makaritsis Kostantinos Vadikolias Chrysoula Liantinioti Maria Chondrogianni Nicola Mumoli Domenico Consoli Franco Galati Simona Sacco Antonio Carolei Cindy Tiseo Francesco Corea Walter Ageno Marta Bellesini Giorgio Silvestrelli Alfonso Ciccone Umberto Scoditti Licia Denti Michelangelo Mancuso Miriam Maccarrone Giovanni Orlandi Nicola Giannini Gino Gialdini Tiziana Tassinari Maria Luisa De Lodovici Giorgio Bono Christina Rueckert Antonio Baldi Danilo Toni Federica Letteri Martina Giuntini Enrico M Lotti Yuriy Flomin Alessio Pieroni Odysseas Kargiotis Theodore Karapanayiotides Serena Monaco Mario M Baronello Laszló Csiba Lilla Szabó Alberto Chiti Elisa Giorli Massimo Del Sette Davide Imberti Dorjan Zabzuni Boris Doronin Vera Volodina Patrik Michel Pd-Mer Peter Vanacker Kristian Barlinn Lars P Pallesen Jessica Kepplinger Dirk Deleu Gayane Melikyan Faisal Ibrahim Naveed Akhtar Vanessa Gourbali Shadi Yaghi Valeria Caso

Eur Stroke J 2019 Mar 25;4(1):55-64. Epub 2018 Jul 25.

Stroke Unit and Division of Cardiovascular Medicine, University of Perugia, Perugia, Italy.

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http://dx.doi.org/10.1177/2396987318785853DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6533867PMC
March 2019

Scoring System to Optimize Pioglitazone Therapy After Stroke Based on Fracture Risk.

Stroke 2018 Dec 10:STROKEAHA118022745. Epub 2018 Dec 10.

From the Department of Internal Medicine, General Medicine, Yale University School of Medicine, New Haven, CT (C.M.V., W.N.K.).

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http://dx.doi.org/10.1161/STROKEAHA.118.022745DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6557695PMC
December 2018

Hemorrhagic Transformation in Patients With Acute Ischemic Stroke and Atrial Fibrillation: Time to Initiation of Oral Anticoagulant Therapy and Outcomes.

Authors:
Maurizio Paciaroni Fabio Bandini Giancarlo Agnelli Georgios Tsivgoulis Shadi Yaghi Karen L Furie Prasanna Tadi Cecilia Becattini Marialuisa Zedde Azmil H Abdul-Rahim Kennedy R Lees Andrea Alberti Michele Venti Monica Acciarresi Cataldo D'Amore Maria Giulia Mosconi Ludovica Anna Cimini Riccardo Altavilla Giacomo Volpi Paolo Bovi Monica Carletti Alberto Rigatelli Manuel Cappellari Jukka Putaala Liisa Tomppo Turgut Tatlisumak Simona Marcheselli Alessandro Pezzini Loris Poli Alessandro Padovani Luca Masotti Vieri Vannucchi Sung-Il Sohn Gianni Lorenzini Rossana Tassi Francesca Guideri Maurizio Acampa Giuseppe Martini George Ntaios George Athanasakis Konstantinos Makaritsis Efstathia Karagkiozi Konstantinos Vadikolias Chrissoula Liantinioti Maria Chondrogianni Nicola Mumoli Domenico Consoli Franco Galati Simona Sacco Antonio Carolei Cindy Tiseo Francesco Corea Walter Ageno Marta Bellesini Giovanna Colombo Giorgio Silvestrelli Alfonso Ciccone Alessia Lanari Umberto Scoditti Licia Denti Michelangelo Mancuso Miriam Maccarrone Leonardo Ulivi Giovanni Orlandi Nicola Giannini Gino Gialdini Tiziana Tassinari Maria Luisa De Lodovici Giorgio Bono Christina Rueckert Antonio Baldi Sebastiano D'Anna Danilo Toni Federica Letteri Martina Giuntini Enrico Maria Lotti Yuriy Flomin Alessio Pieroni Odysseas Kargiotis Theodore Karapanayiotides Serena Monaco Mario Maimone Baronello Laszló Csiba Lilla Szabó Alberto Chiti Elisa Giorli Massimo Del Sette Davide Imberti Dorjan Zabzuni Boris Doronin Vera Volodina Patrik Michel Peter Vanacker Kristian Barlinn Lars-Peder Pallesen Jessica Barlinn Dirk Deleu Gayane Melikyan Faisal Ibrahim Naveed Akhtar Vanessa Gourbali Valeria Caso

J Am Heart Assoc 2018 Nov;7(22):e010133

1 Stroke Unit and Division of Cardiovascular Medicine University of Perugia Italy.

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https://www.ahajournals.org/doi/10.1161/JAHA.118.010133
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http://dx.doi.org/10.1161/JAHA.118.010133DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6404429PMC
November 2018

Response by Lorenzano et al to Letter Regarding Article, "Oxidative Stress Biomarkers of Brain Damage: Hyperacute Plasma F2-Isoprostane Predicts Infarct Growth in Stroke".

Stroke 2018 07 4;49(7):e264. Epub 2018 Jun 4.

Department of Neurology, Rhode Island Hospital, Alpert Medical School of Brown University, Providence.

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http://dx.doi.org/10.1161/STROKEAHA.118.021505DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6019537PMC
July 2018

New biomarker for acute ischaemic stroke: plasma glycogen phosphorylase isoenzyme BB.

J Neurol Neurosurg Psychiatry 2018 04 13;89(4):404-409. Epub 2017 Oct 13.

AA Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1136/jnnp-2017-316084DOI Listing
April 2018

2018 Guidelines for the Early Management of Patients With Acute Ischemic Stroke.

Stroke 2018 03 24;49(3):509-510. Epub 2018 Jan 24.

From the Rhode Island Hospital (K.L.F., M.V.J.), Miriam Hospital (K.L.F.), and Bradley Hospital (K.L.F.), Warren Alpert Medical School, Brown University, Providence, RI.

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https://www.ahajournals.org/doi/10.1161/STROKEAHA.118.020176
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http://dx.doi.org/10.1161/STROKEAHA.118.020176DOI Listing
March 2018

Oxidative Stress Biomarkers of Brain Damage: Hyperacute Plasma F2-Isoprostane Predicts Infarct Growth in Stroke.

Stroke 2018 03 25;49(3):630-637. Epub 2018 Jan 25.

From the J. Philip Kistler Stroke Research Center, Department of Neurology (S.L., N.S.R., F.O.L., M.B.M., R.E.G., T.K.T., A.J.D.), Department of Radiology (H.L., G.J.H.), and Neuroprotection Research Laboratory, Neuroscience Center, Departments of Neurology and Radiology (K.A., A.T.S., L.-D.D.P., E.H.L.), Massachusetts General Hospital, Harvard Medical School, Boston; Department of Neurology, Rhode Island Hospital, Alpert Medical School of Brown University, Providence (M.K., K.L.F.); Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Charlestown (O.W.); Antioxidant Research Laboratory, Jean Mayer USDA Human Nutrition Research Center on Aging (J.B.B.) and Gerald J. and Dorothy R. Friedman School of Nutrition Science and Policy (P.E.M.), Tufts University, Boston, MA; and Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA (S.K.F.).

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http://dx.doi.org/10.1161/STROKEAHA.117.018440DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5828992PMC
March 2018

Effects of pioglitazone on cognitive function in patients with a recent ischaemic stroke or TIA: a report from the IRIS trial.

J Neurol Neurosurg Psychiatry 2018 01 22;89(1):21-27. Epub 2017 Sep 22.

Department of Internal Medicine, Yale School of Medicine, New Haven, Connecticut, USA.

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http://dx.doi.org/10.1136/jnnp-2017-316361DOI Listing
January 2018

Early Elevated Troponin Levels After Ischemic Stroke Suggests a Cardioembolic Source.

Stroke 2018 01 22;49(1):121-126. Epub 2017 Nov 22.

From the Department of Neurology (S.Y., A.D.C., B.A.R., M.H., P.N., K.D., B.M., S.M.C., T.M.B., M.R., K.L.F.), Department of Neurosurgery (M.V.J., R.A.M.), Department of Diagnostic Imaging (M.V.J., R.A.M.), Department of Internal Medicine, Division of Cardiovascular Medicine (C.S., E.M.), and Department of Emergency Medicine (M.S., T.E.M.), Warren Alpert Medical School of Brown University, Providence, RI; Department of Neurology (A.E.M., M.P.L., H.K.) and Feil Family Brain and Mind Research Institute (A.E.M., M.P.L., H.K.), Weill Cornell Medical College, New York, NY; and Department of Neurology, College of Physicians and Surgeons (M.S.V.E.) and Department of Epidemiology, Mailman School of Public Health (M.S.V.E.), Columbia University, New York, NY.

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http://dx.doi.org/10.1161/STROKEAHA.117.019395DOI Listing
January 2018

Structural Integrity of Normal Appearing White Matter and Sex-Specific Outcomes After Acute Ischemic Stroke.

Stroke 2017 12 10;48(12):3387-3389. Epub 2017 Nov 10.

From the Department of Neurology, JPK Stroke Research Center, Massachusetts General Hospital and Harvard Medical School, Boston (M.R.E., O.W., P.C., A.-K.G., L.C., K.M.F., A.S.K., G.B., H.H.K., A.L., N.S.R.); Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology (O.W.) and Division of Neurocritical Care and Emergency Neurology, Department of Neurology and Center for Human Genetic Research (J.R.), Massachusetts General Hospital, Boston; and Department of Neurology, Rhode Island Hospital, Alpert Medical School of Brown University, Providence (K.L.F.).

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http://dx.doi.org/10.1161/STROKEAHA.117.019258DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5726524PMC
December 2017

Early Recurrence and Major Bleeding in Patients With Acute Ischemic Stroke and Atrial Fibrillation Treated With Non-Vitamin-K Oral Anticoagulants (RAF-NOACs) Study.

J Am Heart Assoc 2017 Nov 29;6(12). Epub 2017 Nov 29.

Stroke Unit and Division of Cardiovascular Medicine, University of Perugia, Italy.

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http://dx.doi.org/10.1161/JAHA.117.007034DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5779022PMC
November 2017

PR Interval Prolongation and Cryptogenic Stroke: A Multicenter Retrospective Study.

J Stroke Cerebrovasc Dis 2017 Oct 27;26(10):2416-2420. Epub 2017 Jun 27.

Department of Neurology, The Warren Alpert Medical School of Brown University, Providence, Rhode Island. Electronic address:

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http://dx.doi.org/10.1016/j.jstrokecerebrovasdis.2017.05.036DOI Listing
October 2017

Defining Optimal Brain Health in Adults: A Presidential Advisory From the American Heart Association/American Stroke Association.

Stroke 2017 10 7;48(10):e284-e303. Epub 2017 Sep 7.

Also a member of Maintenance of Brain Health writing group section. Also a member of Optimal Brain Health writing group section. Lead of Maintenance of Brain Health writing group section. Lead of Public Health Impact of Cognitive Impairment, Dementia, Stroke, and Cardiovascular and Stroke Risks writing group section. Senior reviewer.

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http://dx.doi.org/10.1161/STR.0000000000000148DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5654545PMC
October 2017

Smoking cessation and outcome after ischemic stroke or TIA.

Neurology 2017 Oct 8;89(16):1723-1729. Epub 2017 Sep 8.

From the Yale School of Medicine (K.A.E., C.M.V., L.H.Y., S.E.I., B.G., W.N.K.), New Haven, CT; University of Western Ontario (J.D.S.), London, Canada; Maine Medical Center (M.G.), Portland; Fred Hutchinson Cancer Research Center (P.D.G.), Seattle, WA; University of Newcastle Upon Tyne (A.D.), Newcastle, UK; and Alpert Medical School of Brown University (K.L.F.), Providence, RI.

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http://dx.doi.org/10.1212/WNL.0000000000004524DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5644463PMC
October 2017

Cerebral protection for transcatheter aortic valve implantation: A no brainer?

J Thorac Cardiovasc Surg 2017 09 25;154(3):880-883. Epub 2017 May 25.

Department of Neurology, Brown University, Providence, RI.

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http://dx.doi.org/10.1016/j.jtcvs.2016.12.075DOI Listing
September 2017

Translational Stroke Research: Vision and Opportunities.

Stroke 2017 09 27;48(9):2632-2637. Epub 2017 Jul 27.

From the National Institute of Neurological Disorders and Stroke, National Institutes of Health (F.B., J.I.K., R.A.C., L.B.J., S.J., L.M.M., C.S.M., I.R., W.K.); Department of Neurology, Massachusetts General Hospital, Boston (C.A., E.H.L., L.H.S.); Oregon Health & Science University, Portland (S.A.B., M.P.S.-P.); Department of Neurology and Neurological Surgery, University of Washington, Seattle (K.B.); Department of Neurology and Rehabilitation Medicine, University of Cincinnati, OH (J.P.B.); Department of Neurology, University of California, Los Angeles (S.T.C.); Brain Mind Research Institute, Weill Cornell Medicine, New York, NY (S.C., C.I.); Department of Neurological Sciences, University of Vermont, Burlington (M.J. C.); Brain and Mind Research Institute, University of Ottawa, Ontario (D.C.); Department of Neurology, University of California, Irvine, Orange (S.C.C.); Department of Neurological Surgery, University of California, San Francisco (A.R.F.); Stemetix, Inc, Needham, MA (S.F.); Division of Biomedical Sciences, University of California, Riverside (B.D.F.); Department of Neurology, Brown University, Providence, RI (K.L.F.); Department of Neurology, University of California, San Diego (T.M.H.); Department of Emergency Medicine, Medical University of South Carolina, Charleston (E.C.J.); Department of Neurology, University of Virginia, Charlottesville (K.C.J.); Department of Critical Care Medicine (P.M.K.) and Department of Neurology (L.R.W.), University of Pittsburgh, PA; School of Pharmacy, University of North Carolina, Chapel Hill (H.K.); Cedars-Sinai Medical Center, Los Angeles, CA (P.D.L.); University of Gothenburg, Sweden (C.M.); Department of Neurology, University of Texas Health Science Center, Houston (L.D.M., S.I.S.); Mayo Clinic, Jacksonville, FL (J.F.M.); Department of Neurology, University of Miami Miller School, FL (M.A.P.-P.); Department of Neurosurgery, Stanford University, CA (G.K.S.); Division of Fundamental Neurobiology, Krembil Research Institute, Toronto, ON (M.T.); Department of Neurology, University of Texas, Austin (S.W.); and Department of Neurosurgery and Anesthesiology, Loma Linda University, CA (J.H.Z.).

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http://dx.doi.org/10.1161/STROKEAHA.117.017112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5599159PMC
September 2017

The Association between Diffusion MRI-Defined Infarct Volume and NIHSS Score in Patients with Minor Acute Stroke.

J Neuroimaging 2017 07 9;27(4):388-391. Epub 2017 Jan 9.

Division of Social Epidemiology, Department of Neurology, Global Institute of Public Health, NYU Langone Medical Center and Department of Epidemiology, College of Dentistry, New York University, New York, NY.

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http://dx.doi.org/10.1111/jon.12423DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5518742PMC
July 2017

Association of a Primary Stroke Center Protocol for Suspected Stroke by Large-Vessel Occlusion With Efficiency of Care and Patient Outcomes.

JAMA Neurol 2017 07;74(7):793-800

Department of Diagnostic Imaging, Warren Alpert School of Medicine, Brown University, Providence, Rhode Island2Department of Neurology, Warren Alpert School of Medicine, Brown University, Providence, Rhode Island3Department of Neurosurgery, Warren Alpert School of Medicine, Brown University, Providence, Rhode Island4The Norman Prince Neuroscience Institute, Rhode Island Hospital, Providence, Rhode Island.

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http://dx.doi.org/10.1001/jamaneurol.2017.0477DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5710532PMC
July 2017

Genetic Drivers of von Willebrand Factor Levels in an Ischemic Stroke Population and Association With Risk for Recurrent Stroke.

Stroke 2017 06 11;48(6):1444-1450. Epub 2017 May 11.

From the Department of Biostatistical Sciences, Wake Forest School of Medicine, Winston-Salem, NC (F.C.H.); Department of Public Health Sciences (W.M.C., A.M.S., S.S.R., B.B.W., M.M.S.), Department of Neurology (S.R.W., A.M.S., B.B.W.), and Center for Public Health Genomics (W.M.C., S.S.R., B.B.W., M.M.S.), University of Virginia, Charlottesville; Department of Biology (K.L.K.) and Center for Health Disparities (K.L.K.), East Carolina University, Greenville, NC; Department of Clinical Laboratory Sciences, University of Cape Town, South Africa (G.D.); Division of Nutritional Sciences, University of Illinois at Urbana-Champaign (J.L.R.); and Rhode Island Hospital and the Alpert Medical School, Brown University, Providence (K.L.F.).

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http://dx.doi.org/10.1161/STROKEAHA.116.015677DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5536245PMC
June 2017

Cardioembolic Stroke: Mechanisms and Therapeutics.

Semin Neurol 2017 06 31;37(3):326-338. Epub 2017 Jul 31.

Department of Neurology, Warren Alpert Brown Medical School, Providence, Rhode Island.

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http://dx.doi.org/10.1055/s-0037-1603465DOI Listing
June 2017

Cardiac Outcomes After Ischemic Stroke or Transient Ischemic Attack: Effects of Pioglitazone in Patients With Insulin Resistance Without Diabetes Mellitus.

Circulation 2017 May 28;135(20):1882-1893. Epub 2017 Feb 28.

From Yale University School of Medicine, New Haven, CT (L.H.Y., C.M.V., J.P.C., S.E.I., A.M.L., D.L.J., S.E.P., W.N.K.); Denver VA Medical Center and University of Colorado School of Medicine (G.G.S., J.D.A.); Alpert Medical School of Brown University, Providence, RI (K.L.F., J.D.A.); Maine Medical Center, Portland (M.J.G.); National Institutes of Health/National Institute of Neurological Disorders and Stroke, Bethesda, MD (R.C.); University of Pennsylvania Perelman School of Medicine, Philadelphia (D.M.K.); and University of Rochester School of Medicine and Dentistry, NY (F.S.L.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.116.024863DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5511545PMC
May 2017

Integrity of normal-appearing white matter and functional outcomes after acute ischemic stroke.

Neurology 2017 May 5;88(18):1701-1708. Epub 2017 Apr 5.

From the J. Philip Kistler Stroke Research Center (M.R.E., O.W., P.C., A.-K.G., L.C., K.M.F., A.S.K., G.B., H.H.K., A.L., N.S.R.), Department of Neurology, and Athinoula A. Martinos Center for Biomedical Imaging (O.W.), Department of Radiology, Massachusetts General Hospital and Harvard Medical School; Division of Neurocritical Care and Emergency Neurology (J.R.), Department of Neurology and Center for Human Genetic Research, Massachusetts General Hospital, Boston; and Department of Neurology (K.L.F.), Rhode Island Hospital, Alpert Medical School of Brown University, Providence.

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http://dx.doi.org/10.1212/WNL.0000000000003890DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5409847PMC
May 2017

Genetic Risk Prediction of Atrial Fibrillation.

Circulation 2017 Apr 28;135(14):1311-1320. Epub 2016 Oct 28.

From Cardiac Arrhythmia Service (S.A.L., P.T.E.), Cardiovascular Research Center (S.A.L., L.-C.W., S.K., P.T.E.), J. Philip Kistler Stroke Research Center, Department of Neurology (N.S.R., C.D.A., J.R.), and Center for Human Genetic Research (C.D.A., S.K., J.R.), Massachusetts General Hospital, Boston; Program in Medical and Population Genetics, Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge (S.A.L., C.D.A., L.-C.W., S.K., C.R., J.R., P.T.E.); Boston University and National Heart, Lung, and Blood Institute's Framingham Heart Study, MA (X.Y., M.G.L., K.L.L., E.J.B.); Department of Pediatrics (H.J.L., X.G., K.D.T., J.I.R.) and Institute for Translational Genomics and Population Sciences, Los Angeles Biomedical Research Institute (H.J.L., X.G., K.D.T., J.Y., J.I.R.), Harbor-UCLA Medical Center, Torrance, CA; Vanderbilt University, Nashville, TN (M.K., P.L.T., D.D.); Department of Cardiology, Clinical Sciences, Lund University, Sweden (J.G.S.); Skåne University Hospital, Lund, Sweden (J.G.S.); Departments of Cardiology (S.T., J.W.J.) and Gerontology and Geriatrics (S.T.), Leiden University Medical Center, the Netherlands; University of Groningen, University Medical Center Groningen, the Netherlands (M.R., B.G., N.V., J.E.S., P.v.d.H.); Department of Clinical Sciences, Lund University, Malmö, Sweden (P.A., G.E., O.M.); Cardiovascular Division, Department of Medicine, University of Minnesota Medical School, Minneapolis (L.Y.C.); Robertson Center for Biostatistics (I.F.) and Institute of Cardiovascular and Medical Sciences (P.W.M., D.J.S.), University of Glasgow, UK; Department of Neurology, Rhode Island Hospital, Alpert Medical School of Brown University, Providence (K.L.F.); Department of Mathematics and Statistics, Boston University, Boston, MA (M.G.L.); Department of Biostatistics (M.G.L., K.L.L.), Department of Epidemiology (E.J.B.), Section of Cardiovascular Medicine, Department of Medicine (E.J.B.), and Preventive Medicine Section, Department of Medicine (E.J.B.), Boston University School of Public Health, MA; Cardiovascular Health Research Unit, Departments of Medicine (B.M.P., N.S., S.R.H.), Epidemiology (B.M.P., N.S., S.R.H.), and Health Services (B.M.P.), University of Washington, Seattle; Kaiser Permanente Health Research Institute, Kaiser Permanente, Seattle, WA (B.M.P., S.R.H.); Epidemiological Cardiology Research Center (EPICARE), Wake Forest School of Medicine, Winston-Salem, NC (E.Z.S.); Department of Medicine and Molecular Physiology and Biophysics, Vanderbilt University School of Medicine, Nashville, TN (D.R.); University of Illinois, Chicago (D.D.); Interuniversity Cardiology Institute of the Netherlands, Utrecht (J.W.J.); Department of Internal Medicine, Skåne University Hospital, Malmö, Sweden (O.M.); and Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA (A.A.).

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5380586PMC
April 2017

Mechanical embolectomy for acute ischemic stroke beyond six hours from symptom onset using MRI based perfusion imaging.

J Neurol Sci 2017 Apr 22;375:395-400. Epub 2017 Feb 22.

Department of Diagnostic Imaging, The Warren Alpert Medical School of Brown University, Providence, RI, United States; Department of Neurology, The Warren Alpert Medical School of Brown University, Providence, RI, United States; Department of Neurosurgery, The Warren Alpert Medical School of Brown University, Providence, RI, United States.

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April 2017

Prediction of Early Recurrent Thromboembolic Event and Major Bleeding in Patients With Acute Stroke and Atrial Fibrillation by a Risk Stratification Schema: The ALESSA Score Study.

Authors:
Maurizio Paciaroni Giancarlo Agnelli Valeria Caso Georgios Tsivgoulis Karen L Furie Prasanna Tadi Cecilia Becattini Nicola Falocci Marialuisa Zedde Azmil H Abdul-Rahim Kennedy R Lees Andrea Alberti Michele Venti Monica Acciarresi Cataldo D'Amore Maria Giulia Mosconi Ludovica Anna Cimini Antonio Procopio Paolo Bovi Monica Carletti Alberto Rigatelli Manuel Cappellari Jukka Putaala Liisa Tomppo Turgut Tatlisumak Fabio Bandini Simona Marcheselli Alessandro Pezzini Loris Poli Alessandro Padovani Luca Masotti Vieri Vannucchi Sung-Il Sohn Gianni Lorenzini Rossana Tassi Francesca Guideri Maurizio Acampa Giuseppe Martini George Ntaios Efstathia Karagkiozi George Athanasakis Kostantinos Makaritsis Kostantinos Vadikolias Chrysoula Liantinioti Maria Chondrogianni Nicola Mumoli Domenico Consoli Franco Galati Simona Sacco Antonio Carolei Cindy Tiseo Francesco Corea Walter Ageno Marta Bellesini Giovanna Colombo Giorgio Silvestrelli Alfonso Ciccone Umberto Scoditti Licia Denti Michelangelo Mancuso Miriam Maccarrone Giovanni Orlandi Nicola Giannini Gino Gialdini Tiziana Tassinari Maria Luisa De Lodovici Giorgio Bono Christina Rueckert Antonio Baldi Sebastiano D'Anna Danilo Toni Federica Letteri Martina Giuntini Enrico Maria Lotti Yuriy Flomin Alessio Pieroni Odysseas Kargiotis Theodore Karapanayiotides Serena Monaco Mario Maimone Baronello Laszló Csiba Lilla Szabó Alberto Chiti Elisa Giorli Massimo Del Sette Davide Imberti Dorjan Zabzuni Boris Doronin Vera Volodina Patrik Michel Peter Vanacker Kristian Barlinn Lars-Peder Pallesen Jessica Kepplinger Ulf Bodechtel Johannes Gerber Dirk Deleu Gayane Melikyan Faisal Ibrahim Naveed Akhtar Vanessa Gourbali Shadi Yaghi

Stroke 2017 03 9;48(3):726-732. Epub 2017 Feb 9.

From the Stroke Unit and Division of Cardiovascular Medicine, University of Perugia, Italy (M.P., G. Agnelli, V.C., C.B., N.F., A.A., M.V., M. Acciarresi, C.D., M.G.M., L.A.C., A. Procopio); Department of Neurology, Democritus University of Thrace, University Hospital of Alexandroupolis, Greece (G.T., K.V.); International Clinic Research Center, St Anne's University Hospital Brno, Czech Republic (G.T.); Second Department of Neurology, "Attikon" Hospital, University of Athens, School of Medicine, Greece (G.T., C.L., M. Chondrogianni); Division of Stroke and Cerebrovascular Diseases, Department of Neurology, The Warren Alpert Medical School of Brown University, Providence, RI (K.L.F., P.T., S.Y.); Neurology Unit, Stroke Unit, Arcispedale Santa Maria Nuova, IRCCS, Reggio Emilia, Italy (M.Z.); Medical School and Institute of Cardiovascular and Medical Sciences, University of Glasgow, United Kingdom (A.H.A.-R., K.R.L.); Unità Semplice Dipartimentale (USD) Stroke Unit, DAI di Neuroscienze, AOUI Verona, Italy (P.B., M. Carletti, A.R., M. Cappellari); Department of Neurology, Helsinki University Central Hospital, Finland (J.P., L.T., T. Tatlisumak); Institute of Neuroscience and Physiology, Sahlgrenska Academy at University of Gothenburg and Department of Neurology, Sahlgrenska University Hospital, Sweden (T. Tatlisumak); Department of Neurology, Ospedale San Paolo, Savona, Italy (F.B.); Neurologia d'urgenza e Stroke Unit, Istituto Clinico Humanitas, Rozzano, Milano, Italy (S. Marcheselli); Department of Clinical and Experimental Sciences, Neurology Unit, University of Brescia, Italy (A. Pezzini, L.P., A. Padovani); Internal Medicine, Santa Maria Nuova Hospital, Firenze, Italy (L.M., V. Vannucchi); Department of Neurology, Keimyung University School of Medicine, Daegu, South Korea (S.-I.S.); Stroke Unit, AOU Senese, Siena, Italy (G.L.); SC Medicina e Chirurgia d'Accettazione e d'Urgenza, Pontedera o Volterra, Azienda USL Toscana Nord Ovest, Italy (R.T., F. Guideri, M. Acampa, G. Martini); Department of Medicine, University of Thessaly, Larissa, Greece (G.N., E.K., G. Athanasakis, K.M.); Department of Internal Medicine, Ospedale Civile di Livorno, Italy (N.M.); Stroke Unit, Jazzolino Hospital, Vibo Valentia, Italy (D.C., F. Galati); Department of Applied Clinical Sciences and Biotechnology, University of L'Aquila, Italy (S.S., A. Carolei, C.T.); UO Gravi Cerebrolesioni, San Giovanni Battista Hospital, Foligno (F.C.); Department of Clinical and Experimental Medicine, Insubria University, Varese, Italy (W.A., M.B., G.C.); S.C. di Neurologia e S.S. di Stroke Unit, ASST di Mantova, Mantova, Italy (G.S., A. Ciccone); Stroke Unit, Neuroscience Department, University of Parma, Italy (U.S.); Stroke Unit, Dipartimento Geriatrico Riabilitativo, University of Parma, Italy (L.D.); Clinica Neurologica, Azienda Ospedaliero-Universitaria, Pisa, Italy (M. Mancuso, M. Maccarrone, G.O., N.G., G.G., A. Chiti); Neurologia, Ospedale Apuano, Massa Carrara, Italy (G.O., M.G.); Stroke Unit, Department of Neurology, Santa Corona Hospital, Pietra Ligure (Savona), Italy (T. Tassinari); Stroke Unit, Department of Neurology, Insubria University, Varese, Italy (M.L. D.L., G.B.); Abteilung für Neurologie, Oberschwabenklinik gGmbH, Ravensburg, Germany (C.R.); Stroke Unit, Ospedale di Portogruaro, Portogruaro (Venice), Italy (A.B., S.D.); Department of Neurology and Psychiatry, Sapienza University of Rome, Italy (D.T., F.L., A. Pieroni); U.O. Neurologia Stroke Unit, Ospedale SM delle Croci, Ravenna, Italy (E.M.L.); Stroke and Neurorehabilitation Unit, MC 'Universal Clinic 'Oberig' Kyiv, Ukraine (Y.F.); Stroke Unit, Metropolitan Hospital, Piraeus, Greece (O.K.); 2nd Department of Neurology, AHEPA University Hospital, Thessaloniki, Greece (T.K.); Stroke Unit, Ospedale Civico, Palermo, Italy (S. Monaco, M.M.B.); Stroke Unit, University of Debrecen, Hungary (L.C., L.S.); Stroke Unit, Department of Neurology, Sant'Andrea Hospital, La Spezia, Italy (A. Chiti, E.G., M.D.S.); Divisione di Neurologia, Ospedale Galliera, Genoa, Italy (M.D.S.); Department of Internal Medicine, Ospedale Civile di Piacenza, Italy (D.I., D.Z.); City Hospital No. 1, Novosibirsk State Medical University, Russia (B.D., V. Volodina); Centre Cérébrovasculaire, Service de Neurologie, Département des Neurosciences Cliniques Centre Hopitalier Universitaire Vaudois, Lausanne (Switzerland) (P.M.); Department of Neurology, Born Bunge Institute, Antwerp University Hospital, Antwerp, Belgium (P.V.); Department of Neurology, Dresden University Stroke Center, Germany (K.B., L.-P.P., J.K., U.B., J.G.); Neurology, Hamad Medical Corporation, Doha, Qatar (D.D., G. Melikyan, F.I., N.A.); and Department of Neurology, Evangelismos Hospital, Athens (V.G.).

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March 2017

Cryptogenic Stroke: Research and Practice.

Circ Res 2017 Feb;120(3):527-540

From the Department of Neurology, The Warren Alpert Medical School of Brown University, Providence, RI (S.Y., K.L.F.); Department of Neurology (R.A.B.) and Department of Internal Medicine, Division of Cardiovascular Medicine (R.P.), The Feinberg School of Medicine, Northwestern University, Chicago, IL; and Department of Internal Medicine, Division of Cardiology, Weill Cornell Medicine, New York, NY (P.M.O.).

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February 2017

Cardiac magnetic resonance imaging: a new tool to identify cardioaortic sources in ischaemic stroke.

J Neurol Neurosurg Psychiatry 2017 Jan 22;88(1):31-37. Epub 2016 Sep 22.

Department of Neurology, Feinberg School of Medicine of Northwestern University, Chicago, Illinois, USA.

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January 2017

Revolution in stroke.

J Neurol Neurosurg Psychiatry 2017 01;88(1)

Chinese University of Hong Kong, Shatin, Hong Kong.

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January 2017

Therapies for Hemorrhagic Transformation in Acute Ischemic Stroke.

Curr Treat Options Neurol 2017 Jan;19(1)

Department of Neurology, The Warren Alpert Medical School of Brown University, 353 Eddy Street APC 530, Providence, RI, 02903, USA.

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January 2017

Antecedent Aspirin Use Is Associated with Less Severe Symptoms on Admission for Ischemic Stroke.

J Stroke Cerebrovasc Dis 2016 Oct 18;25(10):2519-25. Epub 2016 Jul 18.

J. Philip Kistler Stroke Research Center, Department of Neurology, Massachusetts General Hospital, Boston, Massachusetts.

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October 2016

The IRIS (Insulin Resistance Intervention after Stroke) trial: A new perspective on pioglitazone.

J Diabetes 2016 Sep 8;8(5):607-9. Epub 2016 Jun 8.

Alpert Medical School, Brown University, Providence, Rhode Island, USA.

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September 2016

Taking care of volunteers in a stroke trial: a new assisted-management strategy.

Stroke Vasc Neurol 2016 Sep 25;1(3):108-114. Epub 2016 Oct 25.

Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut, USA.

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http://dx.doi.org/10.1136/svn-2016-000029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5435205PMC
September 2016

Field Assessment Stroke Triage for Emergency Destination: A Simple and Accurate Prehospital Scale to Detect Large Vessel Occlusion Strokes.

Stroke 2016 08 30;47(8):1997-2002. Epub 2016 Jun 30.

From the Centro de Ciências da Saúde, Curso de Medicina, Universidade de Fortaleza, Fortaleza-CE, Brazil (F.O.L.); Neurovascular Service, Department of Neurology, Federal University of São Paulo, São Paulo-SP, Brazil (G.S.S.); Department of Neurology, Brown University, Providence, RI (K.L.F.); Neuroendovascular and Neurocritical Care Services, Marcus Stroke and Neuroscience Center, Grady Memorial Hospital, Emory University School of Medicine, Atlanta, GA (M.R.F., D.C.H., R.G.N.); Department of Radiology (M.H.L.) and Stroke Service, Department of Neurology (É.C.S.C., A.B.S.), Massachusetts General Hospital, Boston; National Institutes of Health, National Institute of Neurological Disorders and Stroke, Bethesda, MD (W.J.K.); and UCSF Neurovascular Service, Department of Neurology, University of California San Francisco (W.S.S.).

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4961538PMC
August 2016

Pioglitazone after Ischemic Stroke or Transient Ischemic Attack.

N Engl J Med 2016 Apr 17;374(14):1321-31. Epub 2016 Feb 17.

From the School of Medicine (W.N.K., C.M.V., L.H.Y., S.E.I., A.M.L., L.M.B., J.R.O.) and the School of Public Health (P.D.G., P.N.P., J.R.O.), Yale University, New Haven, and the Cooperative Studies Program Coordinating Center, Veteran Affairs (VA) Connecticut HealthCare System, West Haven (P.D.G., P.N.P.) - all in Connecticut; Alpert Medical School, Brown University, Providence, RI (K.L.F.); Vermont College of Medicine, Burlington (M.G.); the National Institute of Neurological Disorders and Stroke, Bethesda, MD (R.C.); the VA Medical Center and the University of Colorado School of Medicine, Denver (G.G.S.); the University of Iowa, Iowa City (H.P.A.); Hôpital Charles LeMoyne, Greenfield Park, QC (L.B.), the University of Western Ontario, London (J.D.S.), and the Center for Neurological Research, Lethbridge, AB (T.R.W.) - all in Canada; University of L'Aquila, L'Aquila, Italy (A.C.); Oregon Health Sciences University, Portland (W.C.); the University of Arizona, Tucson (B.C.); the University of Oxford and Oxford University Hospitals NHS Foundation Trust, Oxfordshire, United Kingdom (G.A.F.); the University of Cincinnati, Cincinnati (D.K.); John Hunter Hospital, University of Newcastle, New Lambton Heights, NSW, Australia (M.W.P.); the University of Heidelberg, Heidelberg, Germany (P.R.); the University of South Carolina School of Medicine, Columbia (S.S.); Sheba Medical Center, Tel Aviv University, Tel Aviv, Israel (D.T.); and the Illinois Neurological Institute-OSF Saint Francis Medical Center and the Department of Neurology, University of Illinois College of Medicine at Peoria, Peoria (D.W.).

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4887756PMC
April 2016

Shared genetic susceptibility of vascular-related biomarkers with ischemic and recurrent stroke.

Neurology 2016 Jan 30;86(4):351-9. Epub 2015 Dec 30.

From the Center for Public Health Genomics (S.R.W., K.L.K., W.-M.C., S.S.R., M.M.S.), Cardiovascular Research Center (S.R.W.), and Departments of Public Health Sciences (A.M.S., B.B.W.), Neurology (P.M., B.B.W.), Medicine (M.M.S.), Biochemistry and Molecular Genetics (M.M.S.), and Public Health Sciences (S.S.R.), University of Virginia, Charlottesville; Department of Biostatistical Sciences (F.-C.H.), Wake Forest School of Medicine, Winston-Salem, NC; National Human Genome Research Institute (E.B.M.), Bethesda, MD; Departments of Neurology (A.M.S., K.L.F.) and Neuroscience (K.L.F.), Brown University, Providence, RI; Department of Neurology (B.C.), University of Arizona, Tucson; Department of Biology (K.L.K.) and Center for Health Disparities (K.L.K.), East Carolina University, Greenville, NC; Department of Biostatistics (S.N., S.M.G.), University of Washington, Seattle; Department of Clinical Laboratory Sciences (G.D.), University of Cape Town, South Africa; Department of Biochemistry (J.L.R.), University of Missouri, Columbia; Institute for Stroke and Dementia Research (R.M.), Klinikum der Universität München, Ludwig-Maximilians-Universität München, Munich, Germany; Department of Biostatistics (J.D.), Boston University School of Public Health; and Departments of Neurology (S.S.) and Medicine (H.L.), Boston University School of Medicine, MA.

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http://www.neurology.org/cgi/doi/10.1212/WNL.000000000000231
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4776093PMC
January 2016

Left Atrial Appendage Function and Stroke Risk.

Stroke 2015 Dec 27;46(12):3554-9. Epub 2015 Oct 27.

From the Division of Stroke and Cerebrovascular Diseases, Department of Neurology (S.Y., K.L.F.), and Division of Cardiology, Department of Internal Medicine (C.S.), The Warren Alpert Medical School of Brown University, Providence, RI; Cardiology Division, Department of Internal Medicine (W.A.G.) and Department of Neurology (M.S.V.E.), College of Physicians and Surgeons, and Department of Epidemiology, Mailman School of Public Health (W.A.G.), Columbia University, New York, NY; and Departments of Neurology and Feil Family Brain and Mind Research Institute, Weill Cornell Medical College, New York, NY (H.K.).

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4659748PMC
December 2015

Integrative Mouse and Human Studies Implicate ANGPT1 and ZBTB7C as Susceptibility Genes to Ischemic Injury.

Stroke 2015 Dec 5;46(12):3514-22. Epub 2015 Nov 5.

From the Department of Neurosurgery (R.D., J.Z., W.L., N.C., B.Q., J.X., J.W., X.Z., X.W.) and Channing Division of Network Medicine, Department of Medicine (R.D., S.T.W.), Brigham and Women's Hospital, Boston, MA; Department of Neurology, Massachusetts General Hospital, Boston (S.L., W.J.D., V.J.V., J.R., N.R.); Department of Neurology and Psychiatry, Sapienza University of Rome, Rome, Italy (S.L.); Department of Chemical Biology, Northwest Agriculture and Forestry University, Shaanxi, People's Republic of China (W.L., J.W.); Department of Neurosurgery, China-Japan Friendship Hospital, Beijing, People's Republic of China (J.X.); The Jackson Laboratory, Bar Harbor, ME (A.B., B.P.); Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine (A.B.) and Department of Neurosurgery (R.M.F.), University of Pittsburgh School of Medicine, PA; Quinnipiac University Frank H. Netter, MD School of Medicine, Hamden, CT (W.J.D.); University of Massachusetts Medical School, Worcester (V.J.V.); and Department of Neurology, Warren Alpert Medical School of Brown University, Providence, RI (K.L.F.).

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5704955PMC
December 2015

Role of Acute Lesion Topography in Initial Ischemic Stroke Severity and Long-Term Functional Outcomes.

Stroke 2015 Sep 21;46(9):2438-44. Epub 2015 Jul 21.

From the Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital (MGH), Charlestown, MA (O.W., S.J.T.M., M.J.R.J.B.); JP Kistler Stroke Research Center, Department of Neurology (L.C., P.T.C.-P., K.F., A.K., J.R., K.L.F., N.S.R.), Division of Neuroradiology, Department of Radiology (W.A.C., P.W.S.), Division of Neurocritical Care and Emergency Neurology (J.R.), and Center for Human Genetic Research (J.R.), MGH, Boston, MA; and Department of Neurology, Brown University, Providence, RI (K.L.F.).

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4550548PMC
September 2015

Metabolic determinants of white matter hyperintensity burden in patients with ischemic stroke.

Atherosclerosis 2015 May 2;240(1):149-53. Epub 2015 Mar 2.

J. Philip Kistler Stroke Research Center, Department of Neurology, Massachusetts General Hospital, Boston, MA 02114, USA; Center for Human Genetic Research, Massachusetts General Hospital, Boston, MA 02114, USA. Electronic address:

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4397184PMC
May 2015

Determinants of white matter hyperintensity burden differ at the extremes of ages of ischemic stroke onset.

J Stroke Cerebrovasc Dis 2015 Mar 6;24(3):649-54. Epub 2014 Nov 6.

Stroke Service, Department of Neurology, Massachusetts General Hospital, Boston, Massachusetts; Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts. Electronic address:

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http://dx.doi.org/10.1016/j.jstrokecerebrovasdis.2014.10.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4359634PMC
March 2015

Genetic overlap between diagnostic subtypes of ischemic stroke.

Stroke 2015 Mar 22;46(3):615-9. Epub 2015 Jan 22.

From the School of Medicine and Public Health (E.G.H., J.A.), School of Biomedical Sciences and Pharmacy (L.F.L., R.J.S.), and School of Nursing and Midwifery (J.M.M.), University of Newcastle, Australia; Clinical Research Design, IT and Statistical Support Unit, Public Health Research Program, Hunter Medical Research Institute, Newcastle, Australia (E.G.H., C.O., J.A.); Department of Clinical Neurosciences, University of Cambridge, UK (M.T., S.B., H.S.M.); Institute for Stroke and Dementia Research, Klinikum der Universität Mün-chen, Ludwig-Maximilians-Universität, Munich, Germany (R.M., M.D.); Center for Human Genetic Research, Massachusetts General Hospital, Boston, MA (G.F., J.R.); Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA (G.F., J.R.); Clinical Trial Service Unit and Epidemiological Studies Unit (J.C.H., R.C.) and Stroke Prevention Research Unit, Nuffield Department of Clinical Neuroscience (P.M.R.), University of Oxford, UK; Department of Medicine (Y.-C.C., B.D.M.) and Department of Neurology (J.W.C., S.J.K.), University of Maryland School of Medicine, Baltimore, MD; Imperial College Cerebrovascular Research Unit (ICCRU), Imperial College, London, UK (I.C.); Cardiovascular Health Research Unit, Department of Medicine (J.C.B., B.M.P., K.L.W.) and Department of Epidemiology (B.M.P.), University of Washington, Seattle, WA; Institute of Molecular Medicine and Human Genetics Center, the University of Texas Health Science Center at Houston, TX (E.B., M.F.); Department of Cerebrovascular Disease, IRCCS Istituto Neurologico Carlo Besta, Milan, Italy (G.B.B., E.A.P.); Department of Neurology, Veterans Affairs Medical Center, Baltimore, MD (J.W.C., S.J.K.); Department of Neurology, Rhode Island Hospital, Providence, RI (K.L.F.); Departments of Epidemiology, Neurology, and Radiology, Erasmus University Medical Center, Rotterdam, the Netherlands (M.A.I.); School of Medicine, University of Adelaide, Australia (J.J.); H

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4342266PMC
March 2015

World Stroke Organization global stroke services guidelines and action plan.

Int J Stroke 2014 Oct 23;9 Suppl A100:4-13. Epub 2014 Sep 23.

Heart and Stroke Foundation, Etobicoke, ON, Canada; University of Toronto, Toronto, ON, Canada.

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http://journals.sagepub.com/doi/full/10.1111/ijs.12371
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http://dx.doi.org/10.1111/ijs.12371DOI Listing
October 2014

White matter hyperintensity volume correlates with matrix metalloproteinase-2 in acute ischemic stroke.

J Stroke Cerebrovasc Dis 2014 Jul 16;23(6):1300-6. Epub 2014 Jan 16.

Department of Neurology, Massachusetts General Hospital, Boston, Massachusetts; Department of Neurology, Rhode Island Hospital, Alpert Medical School of Brown University, Providence, Rhode Island.

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http://dx.doi.org/10.1016/j.jstrokecerebrovasdis.2013.11.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4058345PMC
July 2014

Genome-wide association study for circulating tissue plasminogen activator levels and functional follow-up implicates endothelial STXBP5 and STX2.

Authors:
Jie Huang Jennifer E Huffman Munekazu Yamakuchi Munekazu Yamkauchi Stella Trompet Folkert W Asselbergs Maria Sabater-Lleal David-Alexandre Trégouët Wei-Min Chen Nicholas L Smith Marcus E Kleber So-Youn Shin Diane M Becker Weihong Tang Abbas Dehghan Andrew D Johnson Vinh Truong Lasse Folkersen Qiong Yang Tiphaine Oudot-Mellkah Brendan M Buckley Jason H Moore Frances M K Williams Harry Campbell Günther Silbernagel Veronique Vitart Igor Rudan Geoffrey H Tofler Gerjan J Navis Anita Destefano Alan F Wright Ming-Huei Chen Anton J M de Craen Bradford B Worrall Alicja R Rudnicka Ann Rumley Ebony B Bookman Bruce M Psaty Fang Chen Keith L Keene Oscar H Franco Bernhard O Böhm Andre G Uitterlinden Angela M Carter J Wouter Jukema Naveed Sattar Joshua C Bis Mohammad A Ikram Michèle M Sale Barbara McKnight Myriam Fornage Ian Ford Kent Taylor P Eline Slagboom Wendy L McArdle Fang-Chi Hsu Anders Franco-Cereceda Alison H Goodall Lisa R Yanek Karen L Furie Mary Cushman Albert Hofman Jacqueline C M Witteman Aaron R Folsom Saonli Basu Nena Matijevic Wiek H van Gilst James F Wilson Rudi G J Westendorp Sekar Kathiresan Muredach P Reilly Russell P Tracy Ozren Polasek Bernhard R Winkelmann Peter J Grant Hans L Hillege Francois Cambien David J Stott Gordon D Lowe Timothy D Spector James B Meigs Winfried Marz Per Eriksson Lewis C Becker Pierre-Emmanuel Morange Nicole Soranzo Scott M Williams Caroline Hayward Pim van der Harst Anders Hamsten Charles J Lowenstein David P Strachan Christopher J O'Donnell

Arterioscler Thromb Vasc Biol 2014 May 27;34(5):1093-101. Epub 2014 Feb 27.

From National Heart, Lung, and Blood Institute's Framingham Heart Study, Framingham, MA (J.H., A.D.J., C.J.O.); Division of Intramural Research, National Heart, Lung, and Blood Institute, Bethesda, MD (J.H., A.D.J., C.J.O.); MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, Western General Hospital, Edinburgh, Scotland, United Kingdom (J.E.H., V.V., A.F.W., C.H.); The Aab Cardiovascular Research Institute, Department of Medicine, University of Rochester School of Medicine and Dentistry, Rochester, NY (M.Y., C.J.L.); Departments of Cardiology (S.T., J.W.J.), Gerontology and Geriatrics (S.T., A.J.M.d.C., R.G.J.W.), and Molecular Epidemiology (P.E.S.), Leiden University Medical Center, the Netherlands; Department of Cardiology, Division of Heart and Lungs, University Medical Center Utrecht, Utrecht, the Netherlands (F.W.A.); Durrer Center for Cardiogenetic Research, ICIN-Netherlands Heart Institute, Utrecht, the Netherlands (F.W.A.); Institute of Cardiovascular Science, Faculty of Population Health Sciences, University College London, London, United Kingdom (F.W.A.); Cardiovascular Genetics and Genomics Group, Atherosclerosis Research Unit, Department of Medicine (M.S.-L., L.F., P.E., A.H.), Karolinska Institutet, Karolinska University Hospital, Solna, Stockholm, Sweden; INSERM UMRS 937, Pierre et Marie Curie University, Paris, France (D.-A.T., V.T., T.O.M., F.C.); ICAN Institute for Cardiometabolism and Nutrion, Paris, France (D.-A.T., V.T., F.C.); Departments of Public Health Sciences (W.M.C., B.B.W., F.C.) and Biochemistry and Molecular Genetics (M.M.S.), Center for Public Health Genomics, University of Virginia, Charlottesville, VA; Departments of Epidemiology (N.L.S., B.M.P., B.M.), Medicine (B.M.P., J.C.B.), and Health Services (B.M.P.), University of Washington, Seattle, WA; Group Health Research Institute, Group Health Cooperative, Seattle, WA (N.L.S., B.M.P.); Seattle Epidemiologic Research and Information Center, VA Office of Research and

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http://dx.doi.org/10.1161/ATVBAHA.113.302088DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4009733PMC
May 2014

Glyburide is associated with attenuated vasogenic edema in stroke patients.

Neurocrit Care 2014 Apr;20(2):193-201

Center for Human Genetic Research and Division of Neurocritical Care and Emergency Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA,

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http://dx.doi.org/10.1007/s12028-013-9917-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5198519PMC
April 2014

Fluid-attenuated inversion recovery hyperintensity correlates with matrix metalloproteinase-9 level and hemorrhagic transformation in acute ischemic stroke.

Stroke 2014 Apr 11;45(4):1040-5. Epub 2014 Mar 11.

From the Department of Neurology, Massachusetts General Hospital, Boston, MA (R.J., T.W.K.B., L.P., W.T.K.); Department of Neurology and Psychiatry, Policlinico Umberto I Hospital, Sapienza University of Rome, Rome, Italy (S.L.); Department of Neurology, Warren Alpert Medical School of Brown University, Providence, RI (K.L.F.); and Department of Neurology, Yale New Haven Hospital, New Haven, CT (K.N.S.).

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http://dx.doi.org/10.1161/STROKEAHA.113.004627DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3970574PMC
April 2014

Prognosis of untreated strokes due to anterior circulation proximal intracranial arterial occlusions detected by use of computed tomography angiography.

JAMA Neurol 2014 Feb;71(2):151-7

Neuroendovascular and Neurocritical Care Services, Marcus Stroke and Neuroscience Center, Grady Memorial Hospital, Emory University School of Medicine, Atlanta, Georgia.

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http://dx.doi.org/10.1001/jamaneurol.2013.5007DOI Listing
February 2014

Selective ROCK2 Inhibition In Focal Cerebral Ischemia.

Ann Clin Transl Neurol 2014 Jan;1(1):2-14

Neurovascular Research Laboratory, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129 ; Stroke Service and Neuroscience Intensive Care Unit, Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114.

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http://dx.doi.org/10.1002/acn3.19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3900310PMC
January 2014

Clinical examination for prognostication in comatose cardiac arrest patients.

Resuscitation 2013 Nov 15;84(11):1546-51. Epub 2013 Aug 15.

Department of Neurology, Yale University School of Medicine, New Haven, CT, United States; Department of Neurology, Massachusetts General Hospital, Boston, MA, United States. Electronic address:

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http://dx.doi.org/10.1016/j.resuscitation.2013.07.028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4041075PMC
November 2013

Good outcome rate of 35% in IV-tPA-treated patients with computed tomography angiography confirmed severe anterior circulation occlusive stroke.

Stroke 2013 Nov 3;44(11):3109-13. Epub 2013 Sep 3.

From the Department of Radiology (R.G.G., K.L.F., G.V.G., S.K., S.P., G.J.H., E.F.H., E.C.S.C., M.H.L.), and Department of Radiology and Institute for Technology Assessment (E.F.H.), Massachusetts General Hospital and Harvard Medical School, Boston, MA; ICON Medical Imaging (Beacon Bioscience), North Wales, PA (G.V.G.); Department of Neurology (W.S.S.), and Department of Radiology (W.P.D.), University of California at San Francisco, CA; Department of Radiology, University of Minnesota, Minneapolis (S.P.); National Institutes of Neurological Disorders and Stroke, Bethesda, MD (W.J.K.); Department of Neurology, Boston University Medical Center, MA (E.C.S.C.); and Department of Neurology, Rhode Island Hospital and Warren Alpert Medical School, Brown University, Providence, RI (K.L.F.).

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http://dx.doi.org/10.1161/STROKEAHA.113.001938DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4374554PMC
November 2013

Interventional and new approaches to stroke prevention: introduction.

Stroke 2013 Jun;44(6 Suppl 1):S37

Duke University Medical Center, Duke University, Durham, NC 27710, USA.

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http://dx.doi.org/10.1161/STROKEAHA.111.000369DOI Listing
June 2013

Metabolite profiling identifies a branched chain amino acid signature in acute cardioembolic stroke.

Stroke 2013 May 21;44(5):1389-95. Epub 2013 Mar 21.

Center for Human Genetic Research and Division of Neurocritical Care and Emergency Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1161/STROKEAHA.111.000397DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3816089PMC
May 2013

Sex differences and hemoglobin levels in relation to stroke outcomes.

Neurology 2013 Feb 30;80(8):719-24. Epub 2013 Jan 30.

Stroke Service and Division of Neurocritical Care and Emergency Neurology, Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1212/WNL.0b013e31828250ffDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3589294PMC
February 2013

Obesity: a stubbornly obvious target for stroke prevention.

Stroke 2013 Jan 30;44(1):278-86. Epub 2012 Oct 30.

Department of Internal Medicine, Yale University School of Medicine, New Haven, CT, USA.

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http://dx.doi.org/10.1161/STROKEAHA.111.639922DOI Listing
January 2013