Karen I Barnes

Karen I Barnes

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Karen I Barnes

Karen I Barnes

Publications by authors named "Karen I Barnes"

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Why is WHO failing women with falciparum malaria in the first trimester of pregnancy?

Lancet 2020 03;395(10226):779

Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok 10400, Thailand; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UK. Electronic address:

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http://dx.doi.org/10.1016/S0140-6736(20)30161-6DOI Listing
March 2020

Interpretation of Drug Interactions between Dolutegravir and Artemether-Lumefantrine or Artesunate-Amodiaquine.

Antimicrob Agents Chemother 2019 06 24;63(6). Epub 2019 May 24.

Division of Clinical Pharmacology, Department of Medicine, University of Cape Town, Cape Town, South Africa

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http://dx.doi.org/10.1128/AAC.00576-19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6535535PMC
June 2019

Strength in Numbers: The WWARN Case Study of Purpose-Driven Data Sharing.

Am J Trop Med Hyg 2019 01;100(1):13-15

Division of Clinical Pharmacology, Department of Medicine, University of Cape Town, Cape Town, South Africa.

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http://dx.doi.org/10.4269/ajtmh.18-0649DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6335902PMC
January 2019

Secondary analysis and participation of those at the data source.

Lancet Glob Health 2018 09;6(9):e965

Université Cheikh Anta Diop, Dakar, Senegal.

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http://dx.doi.org/10.1016/S2214-109X(18)30341-3DOI Listing
September 2018

Response to "Lactation Status and Studies of Pyrimethamine Pharmacokinetics in Pregnancy".

CPT Pharmacometrics Syst Pharmacol 2017 11 20;6(11):731. Epub 2017 Oct 20.

Division of Clinical Pharmacology, Department of Medicine, University of Cape Town, Cape Town, South Africa.

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http://dx.doi.org/10.1002/psp4.12256DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5702899PMC
November 2017

Working towards consensus on methods used to elicit participant-reported safety data in uncomplicated malaria clinical drug studies: a Delphi technique study.

Malar J 2017 01 28;16(1):52. Epub 2017 Jan 28.

Division of Clinical Pharmacology, Department of Medicine, University of Cape Town, Cape Town, South Africa.

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http://dx.doi.org/10.1186/s12936-017-1699-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5273807PMC
January 2017

The effect of dosing strategies on the therapeutic efficacy of artesunate-amodiaquine for uncomplicated malaria: a meta-analysis of individual patient data.

Authors:
Martin A Adjuik Richard Allan Anupkumar R Anvikar Elizabeth A Ashley Mamadou S Ba Hubert Barennes Karen I Barnes Quique Bassat Elisabeth Baudin Anders Björkman François Bompart Maryline Bonnet Steffen Borrmann Philippe Brasseur Hasifa Bukirwa Francesco Checchi Michel Cot Prabin Dahal Umberto D'Alessandro Philippe Deloron Meghna Desai Graciela Diap Abdoulaye A Djimde Grant Dorsey Ogobara K Doumbo Emmanuelle Espié Jean-Francois Etard Caterina I Fanello Jean-François Faucher Babacar Faye Jennifer A Flegg Oumar Gaye Peter W Gething Raquel González Francesco Grandesso Philippe J Guerin Jean-Paul Guthmann Sally Hamour Armedy Ronny Hasugian Simon I Hay Georgina S Humphreys Vincent Jullien Elizabeth Juma Moses R Kamya Corine Karema Jean R Kiechel Peter G Kremsner Sanjeev Krishna Valérie Lameyre Laminou M Ibrahim Sue J Lee Bertrand Lell Andreas Mårtensson Achille Massougbodji Hervé Menan Didier Ménard Clara Menéndez Martin Meremikwu Clarissa Moreira Carolyn Nabasumba Michael Nambozi Jean-Louis Ndiaye Frederic Nikiema Christian Nsanzabana Francine Ntoumi Bernhards R Ogutu Piero Olliaro Lyda Osorio Jean-Bosco Ouédraogo Louis K Penali Mbaye Pene Loretxu Pinoges Patrice Piola Ric N Price Cally Roper Philip J Rosenthal Claude Emile Rwagacondo Albert Same-Ekobo Birgit Schramm Amadou Seck Bhawna Sharma Carol Hopkins Sibley Véronique Sinou Sodiomon B Sirima Jeffery J Smith Frank Smithuis Fabrice A Somé Doudou Sow Sarah G Staedke Kasia Stepniewska Todd D Swarthout Khadime Sylla Ambrose O Talisuna Joel Tarning Walter R J Taylor Emmanuel A Temu Julie I Thwing Emiliana Tjitra Roger C K Tine Halidou Tinto Michel T Vaillant Neena Valecha Ingrid Van den Broek Nicholas J White Adoke Yeka Issaka Zongo

BMC Med 2015 Mar 31;13:66. Epub 2015 Mar 31.

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http://dx.doi.org/10.1186/s12916-015-0301-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4411752PMC
March 2015

Exploring the seasonality of reported treated malaria cases in Mpumalanga, South Africa.

PLoS One 2013 29;8(10):e76640. Epub 2013 Oct 29.

Department of Statistical Sciences, University of Cape Town, Cape Town, South Africa.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0076640PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3812179PMC
August 2014

Towards malaria elimination in Mpumalanga, South Africa: a population-level mathematical modelling approach.

Malar J 2014 Aug 3;13:297. Epub 2014 Aug 3.

Department of Statistical Sciences, University of Cape Town, Cape Town, South Africa.

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http://dx.doi.org/10.1186/1475-2875-13-297DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4127654PMC
August 2014

Benefits of a pharmacology antimalarial reference standard and proficiency testing program provided by the Worldwide Antimalarial Resistance Network (WWARN).

Antimicrob Agents Chemother 2014 Jul 28;58(7):3889-94. Epub 2014 Apr 28.

Worldwide Antimalarial Resistance Network (WWARN) Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand Centre for Tropical Medicine, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom

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http://dx.doi.org/10.1128/AAC.02362-14DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4068537PMC
July 2014

Effects of amodiaquine and artesunate on sulphadoxine-pyrimethamine pharmacokinetic parameters in children under five in Mali.

Malar J 2011 Sep 21;10:275. Epub 2011 Sep 21.

Molecular Epidemiology and Drug Resistance Unit, Malaria Research and Training Centre, Department of Epidemiology of Parasitic Diseases, Faculty of Medicine, Pharmacy and Dentistry, University of Bamako, P,O, Box: 1805, Bamako, Mali.

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http://dx.doi.org/10.1186/1475-2875-10-275DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3197573PMC
September 2011

Establishing pharmacovigilance programs in resource-limited settings: the example of treating malaria.

Expert Rev Clin Pharmacol 2010 Jul;3(4):509-25

Independent Pharmacovigilance Consultant, Johannesburg, South Africa.

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http://dx.doi.org/10.1586/ecp.10.37DOI Listing
July 2010

Nonlinear mixed effects modeling of gametocyte carriage in patients with uncomplicated malaria.

Malar J 2010 Feb 26;9:60. Epub 2010 Feb 26.

Department of Statistical Sciences, University of Cape Town, Cape Town, South Africa.

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http://dx.doi.org/10.1186/1475-2875-9-60DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2845183PMC
February 2010

Impact of the large-scale deployment of artemether/lumefantrine on the malaria disease burden in Africa: case studies of South Africa, Zambia and Ethiopia.

Malar J 2009 Oct 12;8 Suppl 1:S8. Epub 2009 Oct 12.

Division of Clinical Pharmacology, Department of Medicine, University of Cape Town Faculty of Health Sciences, Anzio Road, Observatory, 7925, South Africa.

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http://dx.doi.org/10.1186/1475-2875-8-S1-S8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2760243PMC
October 2009

Should countries implementing an artemisinin-based combination malaria treatment policy also introduce rapid diagnostic tests?

Malar J 2008 Sep 15;7:176. Epub 2008 Sep 15.

Health Economics Unit, Department of Public Health and Family Medicine, University of Cape Town, Anzio Road, Observatory, 7925 Cape Town, South Africa.

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http://dx.doi.org/10.1186/1475-2875-7-176DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2556342PMC
September 2008

Pharmacokinetics and tolerability of artesunate and amodiaquine alone and in combination in healthy volunteers.

Eur J Clin Pharmacol 2008 Jul 16;64(7):683-90. Epub 2008 Apr 16.

Division of Clinical Pharmacology, Department of Medicine, University of Cape Town, Anzio Road, Observatory, Cape Town, 7925, South Africa.

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http://link.springer.com/10.1007/s00228-007-0452-8
Publisher Site
http://dx.doi.org/10.1007/s00228-007-0452-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2426925PMC
July 2008

Increased gametocytemia after treatment: an early parasitological indicator of emerging sulfadoxine-pyrimethamine resistance in falciparum malaria.

J Infect Dis 2008 Jun;197(11):1605-13

Division of Clinical Pharmacology, Department of Medicine, University of Cape Town, Cape Town, South Africa.

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http://dx.doi.org/10.1086/587645DOI Listing
June 2008

Adverse drug reactions in adult medical inpatients in a South African hospital serving a community with a high HIV/AIDS prevalence: prospective observational study.

Br J Clin Pharmacol 2008 Mar 7;65(3):396-406. Epub 2007 Dec 7.

Division of Clinical Pharmacology, Department of Medicine, University of Cape Town, Observatory 7925, South Africa.

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http://dx.doi.org/10.1111/j.1365-2125.2007.03034.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2291259PMC
March 2008

Antimalarial dosing regimens and drug resistance.

Trends Parasitol 2008 Mar 11;24(3):127-34. Epub 2008 Feb 11.

Division of Clinical Pharmacology, Department of Medicine, University of Cape Town, Cape Town, South Africa.

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http://dx.doi.org/10.1016/j.pt.2007.11.008DOI Listing
March 2008

A network to monitor antimalarial drug resistance: a plan for moving forward.

Trends Parasitol 2008 Jan 26;24(1):43-8. Epub 2007 Nov 26.

Department of Genome Sciences, University of Washington, Seattle, WA, USA.

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http://dx.doi.org/10.1016/j.pt.2007.09.008DOI Listing
January 2008

Malaria pharmacovigilance in Africa: lessons from a pilot project in Mpumalanga Province, South Africa.

Drug Saf 2007 ;30(10):899-910

Division of Clinical Pharmacology, University of Cape Town, Cape Town, South Africa.

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http://dx.doi.org/10.2165/00002018-200730100-00008DOI Listing
December 2007

Rolling back malaria in Africa.

Authors:
Karen I Barnes

S Afr Med J 2007 Jan;97(1):36-7

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January 2007

The pharmacokinetics of intravenous artesunate in adults with severe falciparum malaria.

Eur J Clin Pharmacol 2006 Dec 7;62(12):1003-9. Epub 2006 Nov 7.

Faculty of Tropical Medicine, Mahidol University, 420/6 Rajvithi Rd., Bangkok 10400, Thailand.

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http://link.springer.com/10.1007/s00228-006-0203-2
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http://dx.doi.org/10.1007/s00228-006-0203-2DOI Listing
December 2006

Sulfadoxine-pyrimethamine pharmacokinetics in malaria: pediatric dosing implications.

Clin Pharmacol Ther 2006 Dec;80(6):582-96

Division of Clinical Pharmacology and Department of Statistical Sciences, University of Cape Town, Cape Town, South Africa.

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http://dx.doi.org/10.1016/j.clpt.2006.08.016DOI Listing
December 2006

Association between the pharmacokinetics and in vivo therapeutic efficacy of sulfadoxine-pyrimethamine in Malawian children.

Antimicrob Agents Chemother 2005 Sep;49(9):3601-6

University of Cape Town, Division of Clinical Pharmacology, K50 Old Main Building, Groote Schuur Hospital, Cape Town 7925, South Africa.

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http://dx.doi.org/10.1128/AAC.49.9.3601-3606.2005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1195435PMC
September 2005

Population biology and antimalarial resistance: The transmission of antimalarial drug resistance in Plasmodium falciparum.

Acta Trop 2005 Jun;94(3):230-40

Division of Clinical Pharmacology, Department of Medicine, University of Cape Town, Cape Town 7925, South Africa.

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http://dx.doi.org/10.1016/j.actatropica.2005.04.014DOI Listing
June 2005

Artemisinin-based combination therapy reduces expenditure on malaria treatment in KwaZulu Natal, South Africa.

Trop Med Int Health 2004 Sep;9(9):959-66

Health Sciences Faculty, University of Cape Town, South Africa.

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http://dx.doi.org/10.1111/j.1365-3156.2004.01292.xDOI Listing
September 2004

Measuring resistance to malaria.

S Afr Med J 2004 Jan;94(1):36-7

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January 2004