Publications by authors named "Karen E Weck"

73Publications

Recommendations for Clinical Warfarin Genotyping Allele Selection: A Report of the Association for Molecular Pathology and the College of American Pathologists.

J Mol Diagn 2020 Jul 4;22(7):847-859. Epub 2020 May 4.

The Pharmacogenomics Working Group of the Clinical Practice Committee, Association for Molecular Pathology, Rockville, Maryland; Departments of Pathology and Laboratory Medicine and Genetics, University of North Carolina, Chapel Hill, North Carolina.

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http://dx.doi.org/10.1016/j.jmoldx.2020.04.204DOI Listing
July 2020

Projected impact of pharmacogenomic testing on medications beyond antiplatelet therapy in percutaneous coronary intervention patients.

Pharmacogenomics 2020 05 28;21(7):431-441. Epub 2020 Apr 28.

Division of Pharmacotherapy & Experimental Therapeutics, UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.

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http://dx.doi.org/10.2217/pgs-2019-0185DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7252508PMC
May 2020

Genotype and Phenotype Concordance for Pharmacogenetic Tests Through Proficiency Survey Testing.

Arch Pathol Lab Med 2020 Sep;144(9):1057-1066

Department of Pathology and Laboratory Medicine and Department of Genetics, University of North Carolina, Chapel Hill (Weck).

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http://dx.doi.org/10.5858/arpa.2019-0478-CPDOI Listing
September 2020

Assessing the implications of positive genomic screening results.

Per Med 2020 03 3;17(2):101-109. Epub 2020 Mar 3.

Department of Social Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC 27516, USA.

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http://dx.doi.org/10.2217/pme-2019-0067DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7147673PMC
March 2020

Frequency and clinical outcomes of CYP2C19 genotype-guided escalation and de-escalation of antiplatelet therapy in a real-world clinical setting.

Genet Med 2020 01 18;22(1):160-169. Epub 2019 Jul 18.

Division of Pharmacotherapy and Experimental Therapeutics, UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.

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http://dx.doi.org/10.1038/s41436-019-0611-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6946839PMC
January 2020

Recommendations for Clinical CYP2C9 Genotyping Allele Selection: A Joint Recommendation of the Association for Molecular Pathology and College of American Pathologists.

J Mol Diagn 2019 09 8;21(5):746-755. Epub 2019 May 8.

The Pharmacogenomics (PGx) Working Group of the Clinical Practice Committee, Association for Molecular Pathology, Bethesda, Maryland; Department of Pathology and Laboratory Medicine and Department of Genetics, University of North Carolina, Chapel Hill, North Carolina.

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http://dx.doi.org/10.1016/j.jmoldx.2019.04.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7057225PMC
September 2019

CYP2C19 Genotype-Guided Antiplatelet Therapy and 30-Day Outcomes After Percutaneous Coronary Intervention.

Circ Genom Precis Med 2019 02;12(2):e002441

Division of Pharmacotherapy and Experimental Therapeutics, Eshelman School of Pharmacy (A.K.W., J.M., C.R.L.), School of Medicine, University of North Carolina at Chapel Hill.

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http://dx.doi.org/10.1161/CIRCGEN.119.002441DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7014555PMC
February 2019

The prevalence of the defining features of primary ciliary dyskinesia within a cri du chat syndrome cohort.

Pediatr Pulmonol 2018 11 20;53(11):1565-1573. Epub 2018 Sep 20.

Department of Pediatrics, Division of Pediatric Respiratory Medicine, McGill University Health Centre Research Institute, Montreal, Quebec.

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http://doi.wiley.com/10.1002/ppul.24159
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http://dx.doi.org/10.1002/ppul.24159DOI Listing
November 2018

Clinical Outcomes and Sustainability of Using Genotype-Guided Antiplatelet Therapy After Percutaneous Coronary Intervention.

Circ Genom Precis Med 2018 04;11(4):e002069

Division of Pharmacotherapy and Experimental Therapeutics, UNC Eshelman School of Pharmacy (C.R.L., A.C., K.H., M.J.P., J.A.L.), UNC Center for Pharmacogenomics and Individualized Therapy (C.R.L., K.E.W.), UNC McAllister Heart Institute (C.R.L., G.A.S.), Division of Cardiology, UNC School of Medicine (V.B.S., L.A.H., N.V., S.M., G.A.S.), Department of Pharmacy, UNC HealthCare Medical Center (M.C., J.D.C.), and Department of Pathology and Laboratory Medicine, UNC School of Medicine (K.E.W.), University of North Carolina at Chapel Hill.

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https://www.ahajournals.org/doi/10.1161/CIRCGEN.117.002069
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http://dx.doi.org/10.1161/CIRCGEN.117.002069DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5889089PMC
April 2018

Recommendations for Clinical CYP2C19 Genotyping Allele Selection: A Report of the Association for Molecular Pathology.

J Mol Diagn 2018 05 21;20(3):269-276. Epub 2018 Feb 21.

Pharmacogenomics Working Group of the Clinical Practice Committee, Association for Molecular Pathology, Bethesda, Maryland; Department of Pathology and Laboratory Medicine, University of North Carolina, Chapel Hill, North Carolina; Department of Genetics, University of North Carolina, Chapel Hill, North Carolina.

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http://dx.doi.org/10.1016/j.jmoldx.2018.01.011DOI Listing
May 2018

Interpretation of genomic sequencing: variants should be considered uncertain until proven guilty.

Authors:
Karen E Weck

Genet Med 2018 Mar 1;20(3):291-293. Epub 2018 Feb 1.

Department of Pathology and Laboratory Medicine, Department of Genetics, University of North Carolina, Chapel Hill, North Carolina, USA.

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http://dx.doi.org/10.1038/gim.2017.269DOI Listing
March 2018

Identification of Germline Variants in Tumor Genomic Sequencing Analysis.

J Mol Diagn 2018 01;20(1):123-125

Department of Pathology and Laboratory Medicine, The University of North Carolina School of Medicine, Chapel Hill, North Carolina; Lineberger Comprehensive Cancer Center, The University of North Carolina School of Medicine, Chapel Hill, North Carolina. Electronic address:

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http://dx.doi.org/10.1016/j.jmoldx.2017.09.008DOI Listing
January 2018

Multisite Investigation of Outcomes With Implementation of CYP2C19 Genotype-Guided Antiplatelet Therapy After Percutaneous Coronary Intervention.

JACC Cardiovasc Interv 2018 01 1;11(2):181-191. Epub 2017 Nov 1.

Department of Pharmacotherapy and Translational Research, University of Florida, Gainesville, Florida; Department of Medicine, Division of Cardiovascular Medicine, University of Florida, Gainesville, Florida.

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http://dx.doi.org/10.1016/j.jcin.2017.07.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5775044PMC
January 2018

Comprehensive assessment of cytochromes P450 and transporter genetics with endoxifen concentration during tamoxifen treatment.

Pharmacogenet Genomics 2017 11;27(11):402-409

aDepartment of Clinical Pharmacy, University of Michigan College of Pharmacy, Ann Arbor, Michigan bUNC Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, North Carolina cDeBartolo Family Personalized Medicine Institute, Moffitt Cancer Center, Tampa, Florida dDepartment of Clinical Pharmacology, Indiana University, Indianapolis, Indiana eBon Secours Cancer Institute, Richmond, Virginia, USA.

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http://dx.doi.org/10.1097/FPC.0000000000000311DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5659294PMC
November 2017

CAP/ACMG proficiency testing for biochemical genetics laboratories: a summary of performance.

Genet Med 2018 Jan 29;20(1):83-90. Epub 2017 Jun 29.

Department of Pathology and Laboratory Medicine, Women and Infants Hospital, Alpert Medical School of Brown University, Providence, Rhode Island, USA.

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http://dx.doi.org/10.1038/gim.2017.61DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5763156PMC
January 2018

Whole Exome Sequencing Identifies Truncating Variants in Nuclear Envelope Genes in Patients With Cardiovascular Disease.

Circ Cardiovasc Genet 2017 Jun;10(3)

From the Department of Pathology, Duke University, Durham, NC (G.T.H.); Division of Cardiology (B.C.J.), McAllister Heart Institute (B.C.J., L.A.S., W.H., J.L.), Department of Cell and Molecular Physiology (L.A.S., W.H., J.L.), Department of Genetics (D.M., C.S., C.T., B.A.S., E.A.R.-M., B.K., K.C.W., K.E.W., J.P.E., J.S.B.), Department of Pathology and Laboratory Medicine (J.L., K.E.W.), UNC School of Medicine, Chapel Hill; Renaissance Computing Institute, Chapel Hill, NC (K.C.W.); and ECU Heart Institute, Brody School of Medicine, Greenville, NC (H.A.).

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http://dx.doi.org/10.1161/CIRCGENETICS.116.001443DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5497793PMC
June 2017

The Next Generation of Molecular Pathology is Here: Validation of Next-Generation Sequencing Technology for Clinical Molecular Testing Across Multiple Different Disciplines.

Authors:
Karen E Weck

Arch Pathol Lab Med 2017 06;141(6):749-750

From the Department of Pathology and Laboratory Medicine, University of North Carolina at Chapel Hill.

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http://dx.doi.org/10.5858/arpa.2017-0042-EDDOI Listing
June 2017

Development and Validation of Clinical Whole-Exome and Whole-Genome Sequencing for Detection of Germline Variants in Inherited Disease.

Arch Pathol Lab Med 2017 Jun 31;141(6):798-805. Epub 2017 Mar 31.

From the Department of Human Genetics, Emory University School of Medicine, Atlanta, Georgia (Dr Hegde); the Department of Clinical Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia (Dr Santani); the Division of Genomic Diagnostics, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania (Dr Santani); the Department of Pathology, ARUP Laboratories Institute for Clinical and Experimental Pathology, and University of Utah School of Medicine, Salt Lake City (Drs Mao and Voelkerding); the Division of Molecular Diagnostics, Department of Pathology, Virginia Commonwealth University, Richmond (Dr Ferreira-Gonzalez); and the Department of Pathology and Laboratory Medicine, University of North Carolina at Chapel Hill (Dr Weck).

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http://dx.doi.org/10.5858/arpa.2016-0622-RADOI Listing
June 2017

Development and Validation of Targeted Next-Generation Sequencing Panels for Detection of Germline Variants in Inherited Diseases.

Arch Pathol Lab Med 2017 Jun 21;141(6):787-797. Epub 2017 Mar 21.

From the Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia (Dr Santani); the Division of Genomic Diagnostics, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania (Drs Santani, Murrell, and Yu); the Department of Pathology, MGH/Harvard Medical School, Boston, Massachusetts (Dr Funke); the Laboratory for Molecular Medicine at Partners HealthCare, Personalized Medicine, Cambridge, Massachusetts (Dr Funke); the Department of Human Genetics, Emory University School of Medicine, Atlanta, Georgia (Dr Hegde); the Department of Pathology, ARUP Laboratories Institute for Clinical and Experimental Pathology (Dr Mao) and the Department of Pathology (Dr Voelkerding), University of Utah School of Medicine, Salt Lake City; the Division of Molecular Diagnostics, Department of Pathology, Virginia Commonwealth University, Richmond (Dr Ferreira-Gonzalez); Genomics and Bioinformatics, ARUP Laboratories, Salt Lake City, Utah (Dr Voelkerding); and the Department of Pathology and Laboratory Medicine and Genetics, University of North Carolina at Chapel Hill (Dr Weck).

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http://dx.doi.org/10.5858/arpa.2016-0517-RADOI Listing
June 2017

A panoramic view of the accuracy of molecular genetic testing.

Genet Med 2016 12 18;18(12):1188-1189. Epub 2016 Aug 18.

Department of Pathology, Stanford University School of Medicine, Stanford, California, USA.

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http://dx.doi.org/10.1038/gim.2016.116DOI Listing
December 2016

Highly accurate molecular genetic testing for HFE hereditary hemochromatosis: results from 10 years of blinded proficiency surveys by the College of American Pathologists.

Genet Med 2016 12 28;18(12):1206-1213. Epub 2016 Apr 28.

Department of Pathology and Laboratory Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.

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http://dx.doi.org/10.1038/gim.2016.34DOI Listing
December 2016

FNA smears as a potential source of DNA for targeted next-generation sequencing of lung adenocarcinomas.

Cancer Cytopathol 2016 Jun 16;124(6):406-14. Epub 2016 Feb 16.

Pathology and Laboratory Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.

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http://dx.doi.org/10.1002/cncy.21699DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905788PMC
June 2016

Identification of Human Papillomavirus Infection in Cancer Tissue by Targeted Next-generation Sequencing.

Appl Immunohistochem Mol Morphol 2016 08;24(7):490-5

*Department of Pathology and Laboratory Medicine †Lineberger Comprehensive Cancer Center ‡Department of Medicine, Division of Medical Oncology, The University of North Carolina, Chapel Hill, NC.

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http://dx.doi.org/10.1097/PAI.0000000000000215DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4791202PMC
August 2016

CSER and eMERGE: current and potential state of the display of genetic information in the electronic health record.

J Am Med Inform Assoc 2015 Nov 3;22(6):1231-42. Epub 2015 Jul 3.

Genome Medicine Institute, Geisinger Medical Center, Danville, PA, USA Department of Medicine, Program for Personalized and Genomic Medicine and Center for Health-Related Informatics and Bioimaging, University of Maryland School of Medicine, Baltimore, MD, USA.

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http://dx.doi.org/10.1093/jamia/ocv065DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5009914PMC
November 2015

High Diagnostic Yield of Whole Exome Sequencing in Participants With Retinal Dystrophies in a Clinical Ophthalmology Setting.

Am J Ophthalmol 2015 Aug 22;160(2):354-363.e9. Epub 2015 Apr 22.

Department of Ophthalmology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.

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http://dx.doi.org/10.1016/j.ajo.2015.04.026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4506879PMC
August 2015

Implementation and evaluation of a CYP2C19 genotype-guided antiplatelet therapy algorithm in high-risk coronary artery disease patients.

Pharmacogenomics 2015 ;16(4):303-13

Division of Pharmacotherapy & Experimental Therapeutics, UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.

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http://dx.doi.org/10.2217/pgs.14.180DOI Listing
January 2016

College of American Pathologists' laboratory standards for next-generation sequencing clinical tests.

Arch Pathol Lab Med 2015 Apr 25;139(4):481-93. Epub 2014 Aug 25.

From Molecular Medicine (Dr Aziz), Laboratory Improvement Programs (Dr Zhao and Ms Palicki), and Laboratory Accreditation and Regulatory Affairs (Ms Driscoll), College of American Pathologists, Northfield, Illinois; the Department of Pathology, Brigham & Women's Hospital, Harvard Medical School, Boston, Massachusetts (Dr Bry); the Department of Pathology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts (Dr Funke); the Department of Clinical Sciences, University of Central Florida College of Medicine, Orlando (Dr Gibson); the Divisions of Medical Genetics and Molecular Diagnostics, Department of Pathology & Laboratory Medicine, Pediatrics, and Human Genetics, UCLA School of Medicine, UCLA Institute for Society and Genetics, Molecular Diagnostic Laboratories and Clinical Genomics Center, UCLA Medical Center, Los Angeles, California (Dr Grody); the Department of Human Genetics, Emory University School of Medicine, Decatur, Georgia (Dr Hegde); Robert J. Tomsich Pathology & Laboratory Medicine Institute, Cleveland Clinic, Cleveland, Ohio (Dr Hoeltge); the Department of Pathology, University of Vermont College of Medicine, Burlington (Dr Leonard); the Departments of Pathology (Drs Merker and Schrijver) and Pediatrics (Dr Schrijver), Stanford University School of Medicine, Stanford, California; the Department of Pathology & Immunology, Washington University School of Medicine, St Louis, Missouri (Dr Nagarajan); the Department of Laboratory Medicine & Pathology, Mayo Clinic in Arizona, Phoenix (Dr Robetorye); the Departments of Pathology & Laboratory Medicine and Genetics, University of North Carolina at Chapel Hill, Chapel Hill (Dr Weck); and ARUP Laboratories Institute for Clinical and Experimental Pathology, and Department of Pathology, University of Utah School of Medicine, Salt Lake City (Dr Voelkerding). Dr Aziz is now with Phoenix Children's Hospital, Phoenix, Arizona.

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http://dx.doi.org/10.5858/arpa.2014-0250-CPDOI Listing
April 2015

Molecular genetic testing for cystic fibrosis: laboratory performance on the College of American Pathologists external proficiency surveys.

Genet Med 2015 Mar 31;17(3):219-25. Epub 2014 Jul 31.

Department of Pathology and Laboratory Medicine, Women & Infants Hospital, Alpert Medical School, Brown University, Providence, Rhode Island, USA.

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http://dx.doi.org/10.1038/gim.2014.93DOI Listing
March 2015

Cri du chat syndrome and primary ciliary dyskinesia: a common genetic cause on chromosome 5p.

J Pediatr 2014 Oct 25;165(4):858-61. Epub 2014 Jul 25.

Department of Pathology and Laboratory Medicine, University of North Carolina, Chapel Hill, NC.

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http://dx.doi.org/10.1016/j.jpeds.2014.06.048DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4177261PMC
October 2014

Methods-based proficiency testing in molecular genetic pathology.

J Mol Diagn 2014 May 18;16(3):283-7. Epub 2014 Mar 18.

Department of Pathology and Laboratory Medicine, University of North Carolina, Chapel Hill, North Carolina; Department of Genetics, University of North Carolina, Chapel Hill, North Carolina.

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http://dx.doi.org/10.1016/j.jmoldx.2014.02.002DOI Listing
May 2014

Podocyte-associated gene mutation screening in a heterogeneous cohort of patients with sporadic focal segmental glomerulosclerosis.

Nephrol Dial Transplant 2014 Nov 4;29(11):2062-9. Epub 2014 Feb 4.

Department of Pathology and Laboratory Medicine, University of North Carolina, Chapel Hill, NC, USA.

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http://ndt.oxfordjournals.org/content/early/2014/08/08/ndt.g
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http://ndt.oxfordjournals.org/cgi/doi/10.1093/ndt/gft532
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http://dx.doi.org/10.1093/ndt/gft532DOI Listing
November 2014

Impact of genotype-guided dosing on anticoagulation visits for adults starting warfarin: a randomized controlled trial.

Pharmacogenomics 2013 Oct;14(13):1593-603

Department of Medicine, University of North Carolina at Chapel Hill School of Medicine, 5034 Old Clinic Building, CB #7110, Chapel Hill, NC 27599, USA.

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http://dx.doi.org/10.2217/pgs.13.145DOI Listing
October 2013

A survey of informatics approaches to whole-exome and whole-genome clinical reporting in the electronic health record.

Genet Med 2013 Oct 26;15(10):824-32. Epub 2013 Sep 26.

1] National Institutes of Health National Human Genome Research Institute Clinical Sequencing Exploratory Research Electronic Medical Records Working Group, Bethesda, Maryland, USA [2] University of Washington, Seattle, Washington, USA.

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http://dx.doi.org/10.1038/gim.2013.120DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3951437PMC
October 2013

A novel TRPC6 mutation in a family with podocytopathy and clinical variability.

BMC Nephrol 2013 May 10;14:104. Epub 2013 May 10.

University of North Carolina Kidney Center, UNC School of Medicine, Chapel Hill, NC, USA.

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http://dx.doi.org/10.1186/1471-2369-14-104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3662586PMC
May 2013

Certification in molecular pathology in the United States: an update from the Association for Molecular Pathology Training and Education Committee.

J Mol Diagn 2012 Nov 24;14(6):541-9. Epub 2012 Aug 24.

Association for Molecular Pathology Training and Education Committee, Bethesda, Maryland, USA.

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http://dx.doi.org/10.1016/j.jmoldx.2012.05.004DOI Listing
November 2012

Molecular genetic testing for fragile X syndrome: laboratory performance on the College of American Pathologists proficiency surveys (2001-2009).

Genet Med 2012 Mar 5;14(3):306-12. Epub 2012 Jan 5.

Department of Pathology and Laboratory Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.

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http://dx.doi.org/10.1038/gim.2011.11DOI Listing
March 2012

Design and analytical validation of clinical DNA sequencing assays.

Arch Pathol Lab Med 2012 Jan;136(1):41-6

ARUP Laboratories, Institute of Clinical and Experimental Pathology, Salt Lake City, Utah, USA.

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http://dx.doi.org/10.5858/arpa.2010-0623-OADOI Listing
January 2012

Verification of performance specifications of a molecular test: cystic fibrosis carrier testing using the Luminex liquid bead array.

Arch Pathol Lab Med 2012 Jan;136(1):14-9

Department of Pathology, State University of New York Downstate Medical Center, Brooklyn, 11203, USA.

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http://www.archivesofpathology.org/doi/abs/10.5858/arpa.2010
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http://dx.doi.org/10.5858/arpa.2010-0536-OADOI Listing
January 2012

Phospho-ERK and AKT status, but not KRAS mutation status, are associated with outcomes in rectal cancer treated with chemoradiotherapy.

Radiat Oncol 2011 Sep 12;6:114. Epub 2011 Sep 12.

Department of Medicine, Division of Hematology/Oncology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599-7305, USA.

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http://dx.doi.org/10.1186/1748-717X-6-114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3180690PMC
September 2011

Sensorineural hearing loss in a pediatric population: association of congenital cytomegalovirus infection with intracranial abnormalities.

Arch Otolaryngol Head Neck Surg 2010 Oct;136(10):999-1004

Department of Pathology and Laboratory Medicine, University of North Carolina at Chapel Hill, Campus Box 7600, Chapel Hill, NC 27514, USA.

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http://dx.doi.org/10.1001/archoto.2010.156DOI Listing
October 2010

VKORC1 V66M mutation in African Brazilian patients resistant to oral anticoagulant therapy.

Thromb Res 2010 Sep 7;126(3):e206-10. Epub 2010 Jul 7.

Hematology and Hemotherapy Center, State University of Campinas, Brazil.

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http://dx.doi.org/10.1016/j.thromres.2010.06.008DOI Listing
September 2010

Evolving molecular diagnostics for familial cardiomyopathies: at the heart of it all.

Expert Rev Mol Diagn 2010 Apr;10(3):329-51

PGxHealth Division, Clinical Data, Inc., 5 Science Park, New Haven, CT 06511, USA.

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http://dx.doi.org/10.1586/erm.10.13DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5022563PMC
April 2010

Validation of clinical testing for warfarin sensitivity: comparison of CYP2C9-VKORC1 genotyping assays and warfarin-dosing algorithms.

J Mol Diagn 2009 May 26;11(3):216-25. Epub 2009 Mar 26.

Department of Pathology and Laboratory Medicine, University of North Carolina, Chapel Hill, North Carolina 27599-7525, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S152515781060231
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http://dx.doi.org/10.2353/jmoldx.2009.080123DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2671339PMC
May 2009

Role of the clinical laboratory in personalized medicine: challenges and opportunities.

Per Med 2008 Jan;5(1):1-4

University of North Carolina, Department of Pathology & Laboratory Medicine, Institute of Pharmacogenomics & Individualized Therapy, Chapel Hill, NC, USA.

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http://dx.doi.org/10.2217/17410541.5.1.1DOI Listing
January 2008

Depletion of pulmonary EC-SOD after exposure to hyperoxia.

Am J Physiol Lung Cell Mol Physiol 2002 Oct;283(4):L777-84

Department of Pathology, University of Pittsburgh Medical Center, Pennsylvania 15261, USA.

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http://dx.doi.org/10.1152/ajplung.00011.2002DOI Listing
October 2002

Hepatitis C virus genotyping: interrogation of the 5' untranslated region cannot accurately distinguish genotypes 1a and 1b.

J Clin Microbiol 2002 Sep;40(9):3127-34

Department of Pathology, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC130800PMC
http://dx.doi.org/10.1128/jcm.40.9.3127-3134.2002DOI Listing
September 2002

New cytogenetic variant, insertion (15;17)(q22;q12q21), in an adolescent with acute promyelocytic leukemia.

Cancer Genet Cytogenet 2002 Apr;134(1):55-9

Division of Molecular Diagnostics, Department of Pathology, University of Pittsburgh, Pittsburgh, PA 15213, USA.

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http://dx.doi.org/10.1016/s0165-4608(01)00595-7DOI Listing
April 2002