Karen E Morrison

Karen E Morrison

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Karen E Morrison

Karen E Morrison

Publications by authors named "Karen E Morrison"

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C9orf72 intermediate expansions of 24-30 repeats are associated with ALS.

Acta Neuropathol Commun 2019 Jul 17;7(1):115. Epub 2019 Jul 17.

Department of Basic and Clinical Neuroscience, King's College London, Maurice Wohl Clinical Neuroscience Institute, London, UK.

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http://dx.doi.org/10.1186/s40478-019-0724-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6637621PMC
July 2019

Telomere length is greater in ALS than in controls: a whole genome sequencing study.

Amyotroph Lateral Scler Frontotemporal Degener 2019 May 1;20(3-4):229-234. Epub 2019 Apr 1.

a Department of Basic and Clinical Neuroscience , King's College London, Maurice Wohl Clinical Neuroscience Institute , London , UK.

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http://dx.doi.org/10.1080/21678421.2019.1586951DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6567548PMC
May 2019

Genome-wide Analyses Identify KIF5A as a Novel ALS Gene.

Authors:
Aude Nicolas Kevin P Kenna Alan E Renton Nicola Ticozzi Faraz Faghri Ruth Chia Janice A Dominov Brendan J Kenna Mike A Nalls Pamela Keagle Alberto M Rivera Wouter van Rheenen Natalie A Murphy Joke J F A van Vugt Joshua T Geiger Rick A Van der Spek Hannah A Pliner Shankaracharya Bradley N Smith Giuseppe Marangi Simon D Topp Yevgeniya Abramzon Athina Soragia Gkazi John D Eicher Aoife Kenna Gabriele Mora Andrea Calvo Letizia Mazzini Nilo Riva Jessica Mandrioli Claudia Caponnetto Stefania Battistini Paolo Volanti Vincenzo La Bella Francesca L Conforti Giuseppe Borghero Sonia Messina Isabella L Simone Francesca Trojsi Fabrizio Salvi Francesco O Logullo Sandra D'Alfonso Lucia Corrado Margherita Capasso Luigi Ferrucci Cristiane de Araujo Martins Moreno Sitharthan Kamalakaran David B Goldstein Aaron D Gitler Tim Harris Richard M Myers Hemali Phatnani Rajeeva Lochan Musunuri Uday Shankar Evani Avinash Abhyankar Michael C Zody Julia Kaye Steven Finkbeiner Stacia K Wyman Alex LeNail Leandro Lima Ernest Fraenkel Clive N Svendsen Leslie M Thompson Jennifer E Van Eyk James D Berry Timothy M Miller Stephen J Kolb Merit Cudkowicz Emily Baxi Michael Benatar J Paul Taylor Evadnie Rampersaud Gang Wu Joanne Wuu Giuseppe Lauria Federico Verde Isabella Fogh Cinzia Tiloca Giacomo P Comi Gianni Sorarù Cristina Cereda Philippe Corcia Hannu Laaksovirta Liisa Myllykangas Lilja Jansson Miko Valori John Ealing Hisham Hamdalla Sara Rollinson Stuart Pickering-Brown Richard W Orrell Katie C Sidle Andrea Malaspina John Hardy Andrew B Singleton Janel O Johnson Sampath Arepalli Peter C Sapp Diane McKenna-Yasek Meraida Polak Seneshaw Asress Safa Al-Sarraj Andrew King Claire Troakes Caroline Vance Jacqueline de Belleroche Frank Baas Anneloor L M A Ten Asbroek José Luis Muñoz-Blanco Dena G Hernandez Jinhui Ding J Raphael Gibbs Sonja W Scholz Mary Kay Floeter Roy H Campbell Francesco Landi Robert Bowser Stefan M Pulst John M Ravits Daniel J L MacGowan Janine Kirby Erik P Pioro Roger Pamphlett James Broach Glenn Gerhard Travis L Dunckley Christopher B Brady Neil W Kowall Juan C Troncoso Isabelle Le Ber Kevin Mouzat Serge Lumbroso Terry D Heiman-Patterson Freya Kamel Ludo Van Den Bosch Robert H Baloh Tim M Strom Thomas Meitinger Aleksey Shatunov Kristel R Van Eijk Mamede de Carvalho Maarten Kooyman Bas Middelkoop Matthieu Moisse Russell L McLaughlin Michael A Van Es Markus Weber Kevin B Boylan Marka Van Blitterswijk Rosa Rademakers Karen E Morrison A Nazli Basak Jesús S Mora Vivian E Drory Pamela J Shaw Martin R Turner Kevin Talbot Orla Hardiman Kelly L Williams Jennifer A Fifita Garth A Nicholson Ian P Blair Guy A Rouleau Jesús Esteban-Pérez Alberto García-Redondo Ammar Al-Chalabi Ekaterina Rogaeva Lorne Zinman Lyle W Ostrow Nicholas J Maragakis Jeffrey D Rothstein Zachary Simmons Johnathan Cooper-Knock Alexis Brice Stephen A Goutman Eva L Feldman Summer B Gibson Franco Taroni Antonia Ratti Cinzia Gellera Philip Van Damme Wim Robberecht Pietro Fratta Mario Sabatelli Christian Lunetta Albert C Ludolph Peter M Andersen Jochen H Weishaupt William Camu John Q Trojanowski Vivianna M Van Deerlin Robert H Brown Leonard H van den Berg Jan H Veldink Matthew B Harms Jonathan D Glass David J Stone Pentti Tienari Vincenzo Silani Adriano Chiò Christopher E Shaw Bryan J Traynor John E Landers

Neuron 2018 03;97(6):1268-1283.e6

Department of Neurology, University of Massachusetts Medical School, Worcester, MA 01605, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neuron.2018.02.027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5867896PMC
March 2018

Rare genetic variation in UNC13A may modify survival in amyotrophic lateral sclerosis.

Amyotroph Lateral Scler Frontotemporal Degener 2016 Oct - Nov;17(7-8):593-599. Epub 2016 Sep 1.

a Maurice Wohl Clinical Neuroscience Institute, King's College London, Institute of Psychiatry, Psychology and Neuroscience , London , UK.

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http://dx.doi.org/10.1080/21678421.2016.1213852DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5125285PMC
October 2017

A multicentre evaluation of oropharyngeal secretion management practices in amyotrophic lateral sclerosis.

Amyotroph Lateral Scler Frontotemporal Degener 2017 02 31;18(1-2):1-9. Epub 2016 Aug 31.

a Sheffield Institute for Translational Neuroscience, University of Sheffield, Sheffield, & Academic Directorate of Neurosciences, Royal Hallamshire Hospital, Sheffield Teaching Hospitals NHS Foundation Trust , Sheffield.

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http://dx.doi.org/10.1080/21678421.2016.1221433DOI Listing
February 2017

NEK1 variants confer susceptibility to amyotrophic lateral sclerosis.

Nat Genet 2016 09 25;48(9):1037-42. Epub 2016 Jul 25.

Department of Neurology, University of Massachusetts Medical School, Worcester, Massachusetts, USA.

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http://dx.doi.org/10.1038/ng.3626DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5560030PMC
September 2016

Genome-wide association analyses identify new risk variants and the genetic architecture of amyotrophic lateral sclerosis.

Authors:
Wouter van Rheenen Aleksey Shatunov Annelot M Dekker Russell L McLaughlin Frank P Diekstra Sara L Pulit Rick A A van der Spek Urmo Võsa Simone de Jong Matthew R Robinson Jian Yang Isabella Fogh Perry Tc van Doormaal Gijs H P Tazelaar Max Koppers Anna M Blokhuis William Sproviero Ashley R Jones Kevin P Kenna Kristel R van Eijk Oliver Harschnitz Raymond D Schellevis William J Brands Jelena Medic Androniki Menelaou Alice Vajda Nicola Ticozzi Kuang Lin Boris Rogelj Katarina Vrabec Metka Ravnik-Glavač Blaž Koritnik Janez Zidar Lea Leonardis Leja Dolenc Grošelj Stéphanie Millecamps François Salachas Vincent Meininger Mamede de Carvalho Susana Pinto Jesus S Mora Ricardo Rojas-García Meraida Polak Siddharthan Chandran Shuna Colville Robert Swingler Karen E Morrison Pamela J Shaw John Hardy Richard W Orrell Alan Pittman Katie Sidle Pietro Fratta Andrea Malaspina Simon Topp Susanne Petri Susanne Abdulla Carsten Drepper Michael Sendtner Thomas Meyer Roel A Ophoff Kim A Staats Martina Wiedau-Pazos Catherine Lomen-Hoerth Vivianna M Van Deerlin John Q Trojanowski Lauren Elman Leo McCluskey A Nazli Basak Ceren Tunca Hamid Hamzeiy Yesim Parman Thomas Meitinger Peter Lichtner Milena Radivojkov-Blagojevic Christian R Andres Cindy Maurel Gilbert Bensimon Bernhard Landwehrmeyer Alexis Brice Christine A M Payan Safaa Saker-Delye Alexandra Dürr Nicholas W Wood Lukas Tittmann Wolfgang Lieb Andre Franke Marcella Rietschel Sven Cichon Markus M Nöthen Philippe Amouyel Christophe Tzourio Jean-François Dartigues Andre G Uitterlinden Fernando Rivadeneira Karol Estrada Albert Hofman Charles Curtis Hylke M Blauw Anneke J van der Kooi Marianne de Visser An Goris Markus Weber Christopher E Shaw Bradley N Smith Orietta Pansarasa Cristina Cereda Roberto Del Bo Giacomo P Comi Sandra D'Alfonso Cinzia Bertolin Gianni Sorarù Letizia Mazzini Viviana Pensato Cinzia Gellera Cinzia Tiloca Antonia Ratti Andrea Calvo Cristina Moglia Maura Brunetti Simona Arcuti Rosa Capozzo Chiara Zecca Christian Lunetta Silvana Penco Nilo Riva Alessandro Padovani Massimiliano Filosto Bernard Muller Robbert Jan Stuit Ian Blair Katharine Zhang Emily P McCann Jennifer A Fifita Garth A Nicholson Dominic B Rowe Roger Pamphlett Matthew C Kiernan Julian Grosskreutz Otto W Witte Thomas Ringer Tino Prell Beatrice Stubendorff Ingo Kurth Christian A Hübner P Nigel Leigh Federico Casale Adriano Chio Ettore Beghi Elisabetta Pupillo Rosanna Tortelli Giancarlo Logroscino John Powell Albert C Ludolph Jochen H Weishaupt Wim Robberecht Philip Van Damme Lude Franke Tune H Pers Robert H Brown Jonathan D Glass John E Landers Orla Hardiman Peter M Andersen Philippe Corcia Patrick Vourc'h Vincenzo Silani Naomi R Wray Peter M Visscher Paul I W de Bakker Michael A van Es R Jeroen Pasterkamp Cathryn M Lewis Gerome Breen Ammar Al-Chalabi Leonard H van den Berg Jan H Veldink

Nat Genet 2016 09 25;48(9):1043-8. Epub 2016 Jul 25.

Department of Neurology, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, the Netherlands.

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http://dx.doi.org/10.1038/ng.3622DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5556360PMC
September 2016

CCNF mutations in amyotrophic lateral sclerosis and frontotemporal dementia.

Nat Commun 2016 Apr 15;7:11253. Epub 2016 Apr 15.

Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Macquarie University, Sydney, New South Wales 2109, Australia.

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http://dx.doi.org/10.1038/ncomms11253DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4835537PMC
April 2016

The effects of two polymorphisms on p21cip1 function and their association with Alzheimer's disease in a population of European descent.

PLoS One 2015 27;10(1):e0114050. Epub 2015 Jan 27.

Neuropharmacology and Neurobiology, College of Medical and Dental Sciences, School of Clinical and Experimental Medicine, University of Birmingham, Birmingham, B15 2TT, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0114050PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4308198PMC
January 2016

The role of TREM2 R47H as a risk factor for Alzheimer's disease, frontotemporal lobar degeneration, amyotrophic lateral sclerosis, and Parkinson's disease.

Alzheimers Dement 2015 Dec 30;11(12):1407-1416. Epub 2015 Apr 30.

Platform for Genome Analytics, Institutes of Neurogenetics & Integrative and Experimental Genomics, University of Lübeck, Lübeck, Germany; Department of Vertebrate Genomics, Max Planck Institute for Molecular Genetics, Berlin, Germany; Neuroepidemiology and Ageing Research Unit, School of Public Health, Faculty of Medicine, The Imperial College of Science, Technology, and Medicine, London, UK.

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http://dx.doi.org/10.1016/j.jalz.2014.12.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4627856PMC
December 2015

The CHCHD10 P34S variant is not associated with ALS in a UK cohort of familial and sporadic patients.

Neurobiol Aging 2015 Oct 13;36(10):2908.e17-8. Epub 2015 Jul 13.

Department of Basic and Clinical Neuroscience, Maurice Wohl Clinical Neuroscience Institute, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK. Electronic address:

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http://dx.doi.org/10.1016/j.neurobiolaging.2015.07.014DOI Listing
October 2015

Systematic review and meta-analysis of hydrocarbon exposure and the risk of Parkinson's disease.

Parkinsonism Relat Disord 2015 Mar 26;21(3):243-8. Epub 2014 Dec 26.

School of Clinical and Experimental Medicine, College of Medicine and Dental Sciences, University of Birmingham, Edgbaston, Birmingham, UK; Department of Neurology, Sandwell and West Birmingham Hospitals NHS Trust, Birmingham, UK. Electronic address:

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http://dx.doi.org/10.1016/j.parkreldis.2014.12.017DOI Listing
March 2015

Connections for health, ecosystems and society leading to action and change.

Ecohealth 2014 Sep 20;11(3):279-80. Epub 2014 Jun 20.

Centre de recherche interdisciplinaire sur le bien-être, la santé, la société et l'environnement (Cinbiose), Université du Québec à Montréal, Montréal, QC, Canada,

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http://dx.doi.org/10.1007/s10393-014-0945-8DOI Listing
September 2014

Homozygosity analysis in amyotrophic lateral sclerosis.

Eur J Hum Genet 2013 Dec 24;21(12):1429-35. Epub 2013 Apr 24.

Reta Lila Weston Research Laboratories, Department of Molecular Neuroscience, and Department of Clinical Neuroscience, UCL Institute of Neurology, Queen Square, London, UK.

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http://dx.doi.org/10.1038/ejhg.2013.59DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3829775PMC
December 2013

A multi-centre clinico-genetic analysis of the VPS35 gene in Parkinson disease indicates reduced penetrance for disease-associated variants.

J Med Genet 2012 Nov;49(11):721-6

Department. of Neurodegenerative diseases, Hertie-Institute for Clinical Brain Research and DZNE- German Center for Neurodegenerative Diseases, Tübingen, Hoppe-Seyler-Str. 3, Tübingen 72076, Germany.

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http://dx.doi.org/10.1136/jmedgenet-2012-101155DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3488700PMC
November 2012

Analysis of European case-control studies suggests that common inherited variation in mitochondrial DNA is not involved in susceptibility to amyotrophic lateral sclerosis.

Amyotroph Lateral Scler 2012 Jun 13;13(4):341-6. Epub 2012 Mar 13.

The Centre for Genetic Anthropology, University College London Genetics Institute, Research Department of Genetics, Evolution and Environment, University College London, London WC1E 6BT, UK.

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http://www.tandfonline.com/doi/full/10.3109/17482968.2012.65
Publisher Site
http://dx.doi.org/10.3109/17482968.2012.654394DOI Listing
June 2012

Whole-genome sequencing informs treatment: personalized medicine takes another step forward.

Authors:
Karen E Morrison

Clin Chem 2011 Dec 28;57(12):1638-40. Epub 2011 Sep 28.

University of Birmingham, Birmingham, UK.

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http://dx.doi.org/10.1373/clinchem.2011.172684DOI Listing
December 2011

The use of complementary and alternative medicine by patients attending a UK headache clinic.

Complement Ther Med 2010 Jun-Aug;18(3-4):128-34. Epub 2010 Jun 30.

Division of Neuroscience, University of Birmingham, Birmingham, B15 2TT, UK.

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http://dx.doi.org/10.1016/j.ctim.2010.05.035DOI Listing
January 2011

Broad clinical phenotypes associated with TAR-DNA binding protein (TARDBP) mutations in amyotrophic lateral sclerosis.

Neurogenetics 2010 May 17;11(2):217-25. Epub 2009 Sep 17.

Department of Neuroscience, Faculty of Medicine, Dentistry and Health, University of Sheffield, Medical School, Sheffield, UK.

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http://dx.doi.org/10.1007/s10048-009-0218-9DOI Listing
May 2010

Genetic variants of the alpha-synuclein gene SNCA are associated with multiple system atrophy.

PLoS One 2009 Sep 22;4(9):e7114. Epub 2009 Sep 22.

MRC Centre for Neurodegeneration Research, King's College London, Department of Clinical Neuroscience, Institute of Psychiatry, and NIHR Biomedical Research Centre, London, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0007114PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2743996PMC
September 2009

Frequency and clinical characteristics of progranulin mutation carriers in the Manchester frontotemporal lobar degeneration cohort: comparison with patients with MAPT and no known mutations.

Brain 2008 Mar 11;131(Pt 3):721-31. Epub 2008 Jan 11.

Clinical Neuroscience Research Group, Faculty of Medical and Human Sciences, University of Manchester, Oxford Rd, Manchester M13 9PT, UK.

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http://dx.doi.org/10.1093/brain/awm331DOI Listing
March 2008

TDP-43 gene analysis in frontotemporal lobar degeneration.

Neurosci Lett 2007 May 24;419(1):1-4. Epub 2007 Mar 24.

Division of Regenerative Medicine, Department of Medicine, University of Manchester, Oxford Road, Manchester M13 9PT, UK.

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http://dx.doi.org/10.1016/j.neulet.2007.03.044DOI Listing
May 2007

Amyotrophic lateral sclerosis (motor neuron disease): proposed mechanisms and pathways to treatment.

Expert Rev Mol Med 2006 May 24;8(11):1-22. Epub 2006 May 24.

Division of Neurosciences, University of Birmingham, Edgbaston, Birmingham, B152TT, UK.

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http://dx.doi.org/10.1017/S1462399406010854DOI Listing
May 2006

ANG mutations segregate with familial and 'sporadic' amyotrophic lateral sclerosis.

Nat Genet 2006 Apr 26;38(4):411-3. Epub 2006 Feb 26.

Department of Clinical Neurological Sciences, Royal College of Surgeons in Ireland, Dublin, Ireland.

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http://dx.doi.org/10.1038/ng1742DOI Listing
April 2006

Managing motor neurone disease.

Authors:
Karen E Morrison

Practitioner 2005 Sep;249(1674):612, 614, 617 passim

Department of Clinical Neurosciences, University of Birmingham.

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September 2005

ALS and military service.

Neurology 2005 Jan;64(1):6-7

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http://dx.doi.org/10.1212/01.WNL.0000150535.90358.2DDOI Listing
January 2005

No association with common Caucasian genotypes in exons 8, 13 and 14 of the human cytoplasmic dynein heavy chain gene (DNCHC1) and familial motor neuron disorders.

Amyotroph Lateral Scler Other Motor Neuron Disord 2003 Sep;4(3):150-7

Department of Neurodegenerative Disease, Institute of Neurology National Hospital for Neurology and Neurosurgery, Queen Square, London WC1N 3BG, UK.

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September 2003

Parkin mutations and early onset parkinsonism.

Authors:
Karen E Morrison

Brain 2003 Jun;126(Pt 6):1250-1

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http://dx.doi.org/10.1093/brain/awg189DOI Listing
June 2003

Why does inflammation persist: a dominant role for the stromal microenvironment?

Expert Rev Mol Med 2002 Dec 9;4(25):1-18. Epub 2002 Dec 9.

Division of Neurosciences, University of Birmingham, Birmingham, B15 2TT, UK.

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http://dx.doi.org/10.1017/S1462399402005264DOI Listing
December 2002

Therapies in amyotrophic lateral sclerosis-beyond riluzole.

Authors:
Karen E Morrison

Curr Opin Pharmacol 2002 Jun;2(3):302-9

Department of Neurology, The Medical School, University of Birmingham, Vincent Drive, Edgbaston, B15 2TT, UK.

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June 2002