Publications by authors named "Karen E Cosgrove"

23Publications

Increased proliferation and altered cell cycle regulation in pancreatic stem cells derived from patients with congenital hyperinsulinism.

PLoS One 2019 16;14(9):e0222350. Epub 2019 Sep 16.

Faculty of Biology Medicine and Health, School of Medicine, Division of Diabetes Endocrinology and Gastroenterology, University of Manchester, Manchester, United Kingdom.

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March 2020

Functional and Metabolomic Consequences of K Channel Inactivation in Human Islets.

Diabetes 2017 07 25;66(7):1901-1913. Epub 2017 Apr 25.

Division of Endocrinology and Diabetes, Department of Pediatrics, The Children's Hospital of Philadelphia, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA

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July 2017

Feeding Problems Are Persistent in Children with Severe Congenital Hyperinsulinism.

Front Endocrinol (Lausanne) 2016 9;7. Epub 2016 Feb 9.

Department of Paediatric Endocrinology, Royal Manchester Children's Hospital, Manchester, UK; Faculty of Medical and Human Sciences, University of Manchester, Manchester, UK.

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February 2016

Altered Phenotype of β-Cells and Other Pancreatic Cell Lineages in Patients With Diffuse Congenital Hyperinsulinism in Infancy Caused by Mutations in the ATP-Sensitive K-Channel.

Diabetes 2015 Sep 30;64(9):3182-8. Epub 2015 Apr 30.

Centre for Endocrinology and Diabetes, Institute of Human Development, Faculty of Medical and Human Sciences, Manchester Academic Health Sciences Centre, The University of Manchester, Manchester, U.K. Department of Endocrinology, Central Manchester University Hospitals NHS Foundation Trust, Manchester, U.K.

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September 2015

Reduced Glycemic Variability in Diazoxide-Responsive Children with Congenital Hyperinsulinism Using Supplemental Omega-3-Polyunsaturated Fatty Acids; A Pilot Trial with MaxEPA(R.).

Front Endocrinol (Lausanne) 2014 12;5:31. Epub 2014 Mar 12.

Department of Paediatric Endocrinology, Manchester Academic Health Science Centre, Royal Manchester Children's Hospital, Central Manchester University Hospitals NHS Foundation Trust , Manchester , UK ; Institute of Human Development, Faculty of Medical and Human Sciences, University of Manchester , Manchester , UK.

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March 2014

Can network biology unravel the aetiology of congenital hyperinsulinism?

Orphanet J Rare Dis 2013 Feb 8;8:21. Epub 2013 Feb 8.

Department of Endocrinology, Royal Manchester Children's Hospital, Oxford Road, Manchester M13 9WL, UK.

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February 2013

PAX4 enhances beta-cell differentiation of human embryonic stem cells.

PLoS One 2008 Mar 12;3(3):e1783. Epub 2008 Mar 12.

Centre for Stem Cell Biology, Department of Biomedical Science, The University of Sheffield, Sheffield, United Kingdom.

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March 2008

From congenital hyperinsulinism to diabetes mellitus: the role of pancreatic beta-cell KATP channels.

Pediatr Diabetes 2005 Jun;6(2):103-13

The London Centre for Paediatric Endocrinology and Metabolism, Great Ormond Street Hospital for Children NHS Trust, London, UK.

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June 2005

Genetics and pathophysiology of hyperinsulinism in infancy.

Horm Res 2004 20;61(6):270-88. Epub 2004 Feb 20.

School of Biological Sciences, Stopford Building, University of Manchester, Manchester, UK.

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June 2005