Karen Duff

Karen Duff

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Karen Duff

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Selective vulnerability in neurodegenerative diseases.

Nat Neurosci 2018 10 24;21(10):1350-1358. Epub 2018 Sep 24.

Taub Institute for Research on Alzheimer's Disease and the Aging Brain; and Department of Pathology and Cell Biology, Columbia University Medical Center, New York, NY, USA.

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http://www.nature.com/articles/s41593-018-0221-2
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http://dx.doi.org/10.1038/s41593-018-0221-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360529PMC
October 2018

Targeting the 26S Proteasome To Protect Against Proteotoxic Diseases.

Trends Mol Med 2018 01 9;24(1):18-29. Epub 2017 Dec 9.

Department of Pathology and Cell Biology, The Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Medical Center, New York, NY, USA; Division of Integrative Neuroscience, New York State Psychiatric Institute, New York, NY, USA. Electronic address:

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http://dx.doi.org/10.1016/j.molmed.2017.11.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5905406PMC
January 2018

The Endosomal-Lysosomal Pathway Is Dysregulated by Expression .

Front Neurosci 2017 12;11:702. Epub 2017 Dec 12.

Department of Pathology and Cell Biology, Taub Institute for Research of Alzheimer's Disease and the Aging Brain, Columbia University Medical Center, Colombia University, New York, NY, United States.

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http://dx.doi.org/10.3389/fnins.2017.00702DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5733017PMC
December 2017

Progressive Pathological Changes in Neurochemical Profile of the Hippocampus and Early Changes in the Olfactory Bulbs of Tau Transgenic Mice (rTg4510).

Neurochem Res 2017 Jun 18;42(6):1649-1660. Epub 2017 May 18.

Hoglund Brain Imaging Center, University of Kansas Medical Center, 3901 Rainbow Blvd, Mail Stop 1052, Kansas City, KS, 66160, USA.

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http://dx.doi.org/10.1007/s11064-017-2298-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5565734PMC
June 2017

Tau Pathology Induces Excitatory Neuron Loss, Grid Cell Dysfunction, and Spatial Memory Deficits Reminiscent of Early Alzheimer's Disease.

Neuron 2017 Feb 19;93(3):533-541.e5. Epub 2017 Jan 19.

Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Medical Center, New York, NY 10032, USA; Department of Pathology and Cell Biology, Columbia University Medical Center, New York, NY 10032, USA; Department of Integrative Neuroscience, New York State Psychiatric Institute, New York, NY 10032, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neuron.2016.12.023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363269PMC
February 2017

Tau-driven 26S proteasome impairment and cognitive dysfunction can be prevented early in disease by activating cAMP-PKA signaling.

Nat Med 2016 Jan 21;22(1):46-53. Epub 2015 Dec 21.

Department of Pathology and Cell Biology, Taub Institute for Alzheimer's Disease Research, Columbia University, New York, New York, USA.

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http://dx.doi.org/10.1038/nm.4011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4787271PMC
January 2016

Global axonal transport rates are unaltered in htau mice in vivo.

J Alzheimers Dis 2013 ;37(3):579-86

Center for Dementia Research, Nathan Kline Institute, Orangeburg, NY, USA Department of Psychiatry, New York University School of Medicine, NY, USA.

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http://dx.doi.org/10.3233/JAD-130671DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3819434PMC
June 2014

Vitamin D insufficiency and schizophrenia risk: evaluation of hyperprolinemia as a mediator of association.

Schizophr Res 2014 Jun 29;156(1):15-22. Epub 2014 Apr 29.

Department of Pathology and Cell Biology, Columbia University Medical Center, 630 West 168th Street, New York, United States; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Medical Center, 630 West 168th Street, New York, United States. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S09209964140013
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http://dx.doi.org/10.1016/j.schres.2014.03.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4044915PMC
June 2014

Molecular drivers and cortical spread of lateral entorhinal cortex dysfunction in preclinical Alzheimer's disease.

Nat Neurosci 2014 Feb 22;17(2):304-11. Epub 2013 Dec 22.

1] Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University College of Physicians and Surgeons, New York, New York, USA. [2] Department of Neurology, Columbia University College of Physicians and Surgeons, New York, New York, USA. [3] Department of Radiology, Columbia University College of Physicians and Surgeons, New York, New York, USA.

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http://dx.doi.org/10.1038/nn.3606DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4044925PMC
February 2014

Mechanisms of protein seeding in neurodegenerative diseases.

JAMA Neurol 2013 Mar;70(3):304-10

Yerkes National Primate Research Center, Department of Neurology, Emory University, 954 Gatewood Rd NE, Atlanta,GA 30329, USA.

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http://dx.doi.org/10.1001/jamaneurol.2013.1453DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3665718PMC
March 2013

Trans-synaptic spread of tau pathology in vivo.

PLoS One 2012 1;7(2):e31302. Epub 2012 Feb 1.

Department of Pathology and Cell Biology, Taub Institute for Alzheimer's Disease Research, Columbia University, New York, New York, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0031302PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3270029PMC
June 2012

Contrasting pathology of the stress granule proteins TIA-1 and G3BP in tauopathies.

J Neurosci 2012 Jun;32(24):8270-83

Department of Pharmacology, Boston University School of Medicine, Boston, Massachusetts 02118-2526, USA.

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http://dx.doi.org/10.1523/JNEUROSCI.1592-12.2012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3402380PMC
June 2012

Methylthioninium chloride (methylene blue) induces autophagy and attenuates tauopathy in vitro and in vivo.

Autophagy 2012 Apr 1;8(4):609-22. Epub 2012 Apr 1.

Taub Institute/Department of Pathology, Columbia University and Department of Integrative Neuroscience, New York State Psychiatric Institute, New York, NY, USA.

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http://dx.doi.org/10.4161/auto.19048DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3405840PMC
April 2012

Guidelines for the use and interpretation of assays for monitoring autophagy.

Authors:
Daniel J Klionsky Fabio C Abdalla Hagai Abeliovich Robert T Abraham Abraham Acevedo-Arozena Khosrow Adeli Lotta Agholme Maria Agnello Patrizia Agostinis Julio A Aguirre-Ghiso Hyung Jun Ahn Ouardia Ait-Mohamed Slimane Ait-Si-Ali Takahiko Akematsu Shizuo Akira Hesham M Al-Younes Munir A Al-Zeer Matthew L Albert Roger L Albin Javier Alegre-Abarrategui Maria Francesca Aleo Mehrdad Alirezaei Alexandru Almasan Maylin Almonte-Becerril Atsuo Amano Ravi Amaravadi Shoba Amarnath Amal O Amer Nathalie Andrieu-Abadie Vellareddy Anantharam David K Ann Shailendra Anoopkumar-Dukie Hiroshi Aoki Nadezda Apostolova Giuseppe Arancia John P Aris Katsuhiko Asanuma Nana Y O Asare Hisashi Ashida Valerie Askanas David S Askew Patrick Auberger Misuzu Baba Steven K Backues Eric H Baehrecke Ben A Bahr Xue-Yuan Bai Yannick Bailly Robert Baiocchi Giulia Baldini Walter Balduini Andrea Ballabio Bruce A Bamber Edward T W Bampton Gábor Bánhegyi Clinton R Bartholomew Diane C Bassham Robert C Bast Henri Batoko Boon-Huat Bay Isabelle Beau Daniel M Béchet Thomas J Begley Christian Behl Christian Behrends Soumeya Bekri Bryan Bellaire Linda J Bendall Luca Benetti Laura Berliocchi Henri Bernardi Francesca Bernassola Sébastien Besteiro Ingrid Bhatia-Kissova Xiaoning Bi Martine Biard-Piechaczyk Janice S Blum Lawrence H Boise Paolo Bonaldo David L Boone Beat C Bornhauser Karina R Bortoluci Ioannis Bossis Frédéric Bost Jean-Pierre Bourquin Patricia Boya Michaël Boyer-Guittaut Peter V Bozhkov Nathan R Brady Claudio Brancolini Andreas Brech Jay E Brenman Ana Brennand Emery H Bresnick Patrick Brest Dave Bridges Molly L Bristol Paul S Brookes Eric J Brown John H Brumell Nicola Brunetti-Pierri Ulf T Brunk Dennis E Bulman Scott J Bultman Geert Bultynck Lena F Burbulla Wilfried Bursch Jonathan P Butchar Wanda Buzgariu Sergio P Bydlowski Ken Cadwell Monika Cahová Dongsheng Cai Jiyang Cai Qian Cai Bruno Calabretta Javier Calvo-Garrido Nadine Camougrand Michelangelo Campanella Jenny Campos-Salinas Eleonora Candi Lizhi Cao Allan B Caplan Simon R Carding Sandra M Cardoso Jennifer S Carew Cathleen R Carlin Virginie Carmignac Leticia A M Carneiro Serena Carra Rosario A Caruso Giorgio Casari Caty Casas Roberta Castino Eduardo Cebollero Francesco Cecconi Jean Celli Hassan Chaachouay Han-Jung Chae Chee-Yin Chai David C Chan Edmond Y Chan Raymond Chuen-Chung Chang Chi-Ming Che Ching-Chow Chen Guang-Chao Chen Guo-Qiang Chen Min Chen Quan Chen Steve S-L Chen WenLi Chen Xi Chen Xiangmei Chen Xiequn Chen Ye-Guang Chen Yingyu Chen Yongqiang Chen Yu-Jen Chen Zhixiang Chen Alan Cheng Christopher H K Cheng Yan Cheng Heesun Cheong Jae-Ho Cheong Sara Cherry Russ Chess-Williams Zelda H Cheung Eric Chevet Hui-Ling Chiang Roberto Chiarelli Tomoki Chiba Lih-Shen Chin Shih-Hwa Chiou Francis V Chisari Chi Hin Cho Dong-Hyung Cho Augustine M K Choi DooSeok Choi Kyeong Sook Choi Mary E Choi Salem Chouaib Divaker Choubey Vinay Choubey Charleen T Chu Tsung-Hsien Chuang Sheau-Huei Chueh Taehoon Chun Yong-Joon Chwae Mee-Len Chye Roberto Ciarcia Maria R Ciriolo Michael J Clague Robert S B Clark Peter G H Clarke Robert Clarke Patrice Codogno Hilary A Coller María I Colombo Sergio Comincini Maria Condello Fabrizio Condorelli Mark R Cookson Graham H Coombs Isabelle Coppens Ramon Corbalan Pascale Cossart Paola Costelli Safia Costes Ana Coto-Montes Eduardo Couve Fraser P Coxon James M Cregg José L Crespo Marianne J Cronjé Ana Maria Cuervo Joseph J Cullen Mark J Czaja Marcello D'Amelio Arlette Darfeuille-Michaud Lester M Davids Faith E Davies Massimo De Felici John F de Groot Cornelis A M de Haan Luisa De Martino Angelo De Milito Vincenzo De Tata Jayanta Debnath Alexei Degterev Benjamin Dehay Lea M D Delbridge Francesca Demarchi Yi Zhen Deng Jörn Dengjel Paul Dent Donna Denton Vojo Deretic Shyamal D Desai Rodney J Devenish Mario Di Gioacchino Gilbert Di Paolo Chiara Di Pietro Guillermo Díaz-Araya Inés Díaz-Laviada Maria T Diaz-Meco Javier Diaz-Nido Ivan Dikic Savithramma P Dinesh-Kumar Wen-Xing Ding Clark W Distelhorst Abhinav Diwan Mojgan Djavaheri-Mergny Svetlana Dokudovskaya Zheng Dong Frank C Dorsey Victor Dosenko James J Dowling Stephen Doxsey Marlène Dreux Mark E Drew Qiuhong Duan Michel A Duchosal Karen Duff Isabelle Dugail Madeleine Durbeej Michael Duszenko Charles L Edelstein Aimee L Edinger Gustavo Egea Ludwig Eichinger N Tony Eissa Suhendan Ekmekcioglu Wafik S El-Deiry Zvulun Elazar Mohamed Elgendy Lisa M Ellerby Kai Er Eng Anna-Mart Engelbrecht Simone Engelender Jekaterina Erenpreisa Ricardo Escalante Audrey Esclatine Eeva-Liisa Eskelinen Lucile Espert Virginia Espina Huizhou Fan Jia Fan Qi-Wen Fan Zhen Fan Shengyun Fang Yongqi Fang Manolis Fanto Alessandro Fanzani Thomas Farkas Jean-Claude Farré Mathias Faure Marcus Fechheimer Carl G Feng Jian Feng Qili Feng Youji Feng László Fésüs Ralph Feuer Maria E Figueiredo-Pereira Gian Maria Fimia Diane C Fingar Steven Finkbeiner Toren Finkel Kim D Finley Filomena Fiorito Edward A Fisher Paul B Fisher Marc Flajolet Maria L Florez-McClure Salvatore Florio Edward A Fon Francesco Fornai Franco Fortunato Rati Fotedar Daniel H Fowler Howard S Fox Rodrigo Franco Lisa B Frankel Marc Fransen José M Fuentes Juan Fueyo Jun Fujii Kozo Fujisaki Eriko Fujita Mitsunori Fukuda Ruth H Furukawa Matthias Gaestel Philippe Gailly Malgorzata Gajewska Brigitte Galliot Vincent Galy Subramaniam Ganesh Barry Ganetzky Ian G Ganley Fen-Biao Gao George F Gao Jinming Gao Lorena Garcia Guillermo Garcia-Manero Mikel Garcia-Marcos Marjan Garmyn Andrei L Gartel Evelina Gatti Mathias Gautel Thomas R Gawriluk Matthew E Gegg Jiefei Geng Marc Germain Jason E Gestwicki David A Gewirtz Saeid Ghavami Pradipta Ghosh Anna M Giammarioli Alexandra N Giatromanolaki Spencer B Gibson Robert W Gilkerson Michael L Ginger Henry N Ginsberg Jakub Golab Michael S Goligorsky Pierre Golstein Candelaria Gomez-Manzano Ebru Goncu Céline Gongora Claudio D Gonzalez Ramon Gonzalez Cristina González-Estévez Rosa Ana González-Polo Elena Gonzalez-Rey Nikolai V Gorbunov Sharon Gorski Sandro Goruppi Roberta A Gottlieb Devrim Gozuacik Giovanna Elvira Granato Gary D Grant Kim N Green Aleš Gregorc Frédéric Gros Charles Grose Thomas W Grunt Philippe Gual Jun-Lin Guan Kun-Liang Guan Sylvie M Guichard Anna S Gukovskaya Ilya Gukovsky Jan Gunst Asa B Gustafsson Andrew J Halayko Amber N Hale Sandra K Halonen Maho Hamasaki Feng Han Ting Han Michael K Hancock Malene Hansen Hisashi Harada Masaru Harada Stefan E Hardt J Wade Harper Adrian L Harris James Harris Steven D Harris Makoto Hashimoto Jeffrey A Haspel Shin-ichiro Hayashi Lori A Hazelhurst Congcong He You-Wen He Marie-Joseé Hébert Kim A Heidenreich Miep H Helfrich Gudmundur V Helgason Elizabeth P Henske Brian Herman Paul K Herman Claudio Hetz Sabine Hilfiker Joseph A Hill Lynne J Hocking Paul Hofman Thomas G Hofmann Jörg Höhfeld Tessa L Holyoake Ming-Huang Hong David A Hood Gökhan S Hotamisligil Ewout J Houwerzijl Maria Høyer-Hansen Bingren Hu Chien-An A Hu Hong-Ming Hu Ya Hua Canhua Huang Ju Huang Shengbing Huang Wei-Pang Huang Tobias B Huber Won-Ki Huh Tai-Ho Hung Ted R Hupp Gang Min Hur James B Hurley Sabah N A Hussain Patrick J Hussey Jung Jin Hwang Seungmin Hwang Atsuhiro Ichihara Shirin Ilkhanizadeh Ken Inoki Takeshi Into Valentina Iovane Juan L Iovanna Nancy Y Ip Yoshitaka Isaka Hiroyuki Ishida Ciro Isidoro Ken-ichi Isobe Akiko Iwasaki Marta Izquierdo Yotaro Izumi Panu M Jaakkola Marja Jäättelä George R Jackson William T Jackson Bassam Janji Marina Jendrach Ju-Hong Jeon Eui-Bae Jeung Hong Jiang Hongchi Jiang Jean X Jiang Ming Jiang Qing Jiang Xuejun Jiang Xuejun Jiang Alberto Jiménez Meiyan Jin Shengkan Jin Cheol O Joe Terje Johansen Daniel E Johnson Gail V W Johnson Nicola L Jones Bertrand Joseph Suresh K Joseph Annie M Joubert Gábor Juhász Lucienne Juillerat-Jeanneret Chang Hwa Jung Yong-Keun Jung Kai Kaarniranta Allen Kaasik Tomohiro Kabuta Motoni Kadowaki Katarina Kagedal Yoshiaki Kamada Vitaliy O Kaminskyy Harm H Kampinga Hiromitsu Kanamori Chanhee Kang Khong Bee Kang Kwang Il Kang Rui Kang Yoon-A Kang Tomotake Kanki Thirumala-Devi Kanneganti Haruo Kanno Anumantha G Kanthasamy Arthi Kanthasamy Vassiliki Karantza Gur P Kaushal Susmita Kaushik Yoshinori Kawazoe Po-Yuan Ke John H Kehrl Ameeta Kelekar Claus Kerkhoff David H Kessel Hany Khalil Jan A K W Kiel Amy A Kiger Akio Kihara Deok Ryong Kim Do-Hyung Kim Dong-Hou Kim Eun-Kyoung Kim Hyung-Ryong Kim Jae-Sung Kim Jeong Hun Kim Jin Cheon Kim John K Kim Peter K Kim Seong Who Kim Yong-Sun Kim Yonghyun Kim Adi Kimchi Alec C Kimmelman Jason S King Timothy J Kinsella Vladimir Kirkin Lorrie A Kirshenbaum Katsuhiko Kitamoto Kaio Kitazato Ludger Klein Walter T Klimecki Jochen Klucken Erwin Knecht Ben C B Ko Jan C Koch Hiroshi Koga Jae-Young Koh Young Ho Koh Masato Koike Masaaki Komatsu Eiki Kominami Hee Jeong Kong Wei-Jia Kong Viktor I Korolchuk Yaichiro Kotake Michael I Koukourakis Juan B Kouri Flores Attila L Kovács Claudine Kraft Dimitri Krainc Helmut Krämer Carole Kretz-Remy Anna M Krichevsky Guido Kroemer Rejko Krüger Oleg Krut Nicholas T Ktistakis Chia-Yi Kuan Roza Kucharczyk Ashok Kumar Raj Kumar Sharad Kumar Mondira Kundu Hsing-Jien Kung Tino Kurz Ho Jeong Kwon Albert R La Spada Frank Lafont Trond Lamark Jacques Landry Jon D Lane Pierre Lapaquette Jocelyn F Laporte Lajos László Sergio Lavandero Josée N Lavoie Robert Layfield Pedro A Lazo Weidong Le Laurent Le Cam Daniel J Ledbetter Alvin J X Lee Byung-Wan Lee Gyun Min Lee Jongdae Lee Ju-Hyun Lee Michael Lee Myung-Shik Lee Sug Hyung Lee Christiaan Leeuwenburgh Patrick Legembre Renaud Legouis Michael Lehmann Huan-Yao Lei Qun-Ying Lei David A Leib José Leiro John J Lemasters Antoinette Lemoine Maciej S Lesniak Dina Lev Victor V Levenson Beth Levine Efrat Levy Faqiang Li Jun-Lin Li Lian Li Sheng Li Weijie Li Xue-Jun Li Yan-bo Li Yi-Ping Li Chengyu Liang Qiangrong Liang Yung-Feng Liao Pawel P Liberski Andrew Lieberman Hyunjung J Lim Kah-Leong Lim Kyu Lim Chiou-Feng Lin Fu-Cheng Lin Jian Lin Jiandie D Lin Kui Lin Wan-Wan Lin Weei-Chin Lin Yi-Ling Lin Rafael Linden Paul Lingor Jennifer Lippincott-Schwartz Michael P Lisanti Paloma B Liton Bo Liu Chun-Feng Liu Kaiyu Liu Leyuan Liu Qiong A Liu Wei Liu Young-Chau Liu Yule Liu Richard A Lockshin Chun-Nam Lok Sagar Lonial Benjamin Loos Gabriel Lopez-Berestein Carlos López-Otín Laura Lossi Michael T Lotze Peter Lőw Binfeng Lu Bingwei Lu Bo Lu Zhen Lu Frédéric Luciano Nicholas W Lukacs Anders H Lund Melinda A Lynch-Day Yong Ma Fernando Macian Jeff P MacKeigan Kay F Macleod Frank Madeo Luigi Maiuri Maria Chiara Maiuri Davide Malagoli May Christine V Malicdan Walter Malorni Na Man Eva-Maria Mandelkow Stéphen Manon Irena Manov Kai Mao Xiang Mao Zixu Mao Philippe Marambaud Daniela Marazziti Yves L Marcel Katie Marchbank Piero Marchetti Stefan J Marciniak Mateus Marcondes Mohsen Mardi Gabriella Marfe Guillermo Mariño Maria Markaki Mark R Marten Seamus J Martin Camille Martinand-Mari Wim Martinet Marta Martinez-Vicente Matilde Masini Paola Matarrese Saburo Matsuo Raffaele Matteoni Andreas Mayer Nathalie M Mazure David J McConkey Melanie J McConnell Catherine McDermott Christine McDonald Gerald M McInerney Sharon L McKenna BethAnn McLaughlin Pamela J McLean Christopher R McMaster G Angus McQuibban Alfred J Meijer Miriam H Meisler Alicia Meléndez Thomas J Melia Gerry Melino Maria A Mena Javier A Menendez Rubem F S Menna-Barreto Manoj B Menon Fiona M Menzies Carol A Mercer Adalberto Merighi Diane E Merry Stefania Meschini Christian G Meyer Thomas F Meyer Chao-Yu Miao Jun-Ying Miao Paul A M Michels Carine Michiels Dalibor Mijaljica Ana Milojkovic Saverio Minucci Clelia Miracco Cindy K Miranti Ioannis Mitroulis Keisuke Miyazawa Noboru Mizushima Baharia Mograbi Simin Mohseni Xavier Molero Bertrand Mollereau Faustino Mollinedo Takashi Momoi Iryna Monastyrska Martha M Monick Mervyn J Monteiro Michael N Moore Rodrigo Mora Kevin Moreau Paula I Moreira Yuji Moriyasu Jorge Moscat Serge Mostowy Jeremy C Mottram Tomasz Motyl Charbel E-H Moussa Sylke Müller Sylviane Muller Karl Münger Christian Münz Leon O Murphy Maureen E Murphy Antonio Musarò Indira Mysorekar Eiichiro Nagata Kazuhiro Nagata Aimable Nahimana Usha Nair Toshiyuki Nakagawa Kiichi Nakahira Hiroyasu Nakano Hitoshi Nakatogawa Meera Nanjundan Naweed I Naqvi Derek P Narendra Masashi Narita Miguel Navarro Steffan T Nawrocki Taras Y Nazarko Andriy Nemchenko Mihai G Netea Thomas P Neufeld Paul A Ney Ioannis P Nezis Huu Phuc Nguyen Daotai Nie Ichizo Nishino Corey Nislow Ralph A Nixon Takeshi Noda Angelika A Noegel Anna Nogalska Satoru Noguchi Lucia Notterpek Ivana Novak Tomoyoshi Nozaki Nobuyuki Nukina Thorsten Nürnberger Beat Nyfeler Keisuke Obara Terry D Oberley Salvatore Oddo Michinaga Ogawa Toya Ohashi Koji Okamoto Nancy L Oleinick F Javier Oliver Laura J Olsen Stefan Olsson Onya Opota Timothy F Osborne Gary K Ostrander Kinya Otsu Jing-hsiung James Ou Mireille Ouimet Michael Overholtzer Bulent Ozpolat Paolo Paganetti Ugo Pagnini Nicolas Pallet Glen E Palmer Camilla Palumbo Tianhong Pan Theocharis Panaretakis Udai Bhan Pandey Zuzana Papackova Issidora Papassideri Irmgard Paris Junsoo Park Ohkmae K Park Jan B Parys Katherine R Parzych Susann Patschan Cam Patterson Sophie Pattingre John M Pawelek Jianxin Peng David H Perlmutter Ida Perrotta George Perry Shazib Pervaiz Matthias Peter Godefridus J Peters Morten Petersen Goran Petrovski James M Phang Mauro Piacentini Philippe Pierre Valérie Pierrefite-Carle Gérard Pierron Ronit Pinkas-Kramarski Antonio Piras Natik Piri Leonidas C Platanias Stefanie Pöggeler Marc Poirot Angelo Poletti Christian Poüs Mercedes Pozuelo-Rubio Mette Prætorius-Ibba Anil Prasad Mark Prescott Muriel Priault Nathalie Produit-Zengaffinen Ann Progulske-Fox Tassula Proikas-Cezanne Serge Przedborski Karin Przyklenk Rosa Puertollano Julien Puyal Shu-Bing Qian Liang Qin Zheng-Hong Qin Susan E Quaggin Nina Raben Hannah Rabinowich Simon W Rabkin Irfan Rahman Abdelhaq Rami Georg Ramm Glenn Randall Felix Randow V Ashutosh Rao Jeffrey C Rathmell Brinda Ravikumar Swapan K Ray Bruce H Reed John C Reed Fulvio Reggiori Anne Régnier-Vigouroux Andreas S Reichert John J Reiners Russel J Reiter Jun Ren José L Revuelta Christopher J Rhodes Konstantinos Ritis Elizete Rizzo Jeffrey Robbins Michel Roberge Hernan Roca Maria C Roccheri Stephane Rocchi H Peter Rodemann Santiago Rodríguez de Córdoba Bärbel Rohrer Igor B Roninson Kirill Rosen Magdalena M Rost-Roszkowska Mustapha Rouis Kasper M A Rouschop Francesca Rovetta Brian P Rubin David C Rubinsztein Klaus Ruckdeschel Edmund B Rucker Assaf Rudich Emil Rudolf Nelson Ruiz-Opazo Rossella Russo Tor Erik Rusten Kevin M Ryan Stefan W Ryter David M Sabatini Junichi Sadoshima Tapas Saha Tatsuya Saitoh Hiroshi Sakagami Yasuyoshi Sakai Ghasem Hoseini Salekdeh Paolo Salomoni Paul M Salvaterra Guy Salvesen Rosa Salvioli Anthony M J Sanchez José A Sánchez-Alcázar Ricardo Sánchez-Prieto Marco Sandri Uma Sankar Poonam Sansanwal Laura Santambrogio Shweta Saran Sovan Sarkar Minnie Sarwal Chihiro Sasakawa Ausra Sasnauskiene Miklós Sass Ken Sato Miyuki Sato Anthony H V Schapira Michael Scharl Hermann M Schätzl Wiep Scheper Stefano Schiaffino Claudio Schneider Marion E Schneider Regine Schneider-Stock Patricia V Schoenlein Daniel F Schorderet Christoph Schüller Gary K Schwartz Luca Scorrano Linda Sealy Per O Seglen Juan Segura-Aguilar Iban Seiliez Oleksandr Seleverstov Christian Sell Jong Bok Seo Duska Separovic Vijayasaradhi Setaluri Takao Setoguchi Carmine Settembre John J Shacka Mala Shanmugam Irving M Shapiro Eitan Shaulian Reuben J Shaw James H Shelhamer Han-Ming Shen Wei-Chiang Shen Zu-Hang Sheng Yang Shi Kenichi Shibuya Yoshihiro Shidoji Jeng-Jer Shieh Chwen-Ming Shih Yohta Shimada Shigeomi Shimizu Takahiro Shintani Orian S Shirihai Gordon C Shore Andriy A Sibirny Stan B Sidhu Beata Sikorska Elaine C M Silva-Zacarin Alison Simmons Anna Katharina Simon Hans-Uwe Simon Cristiano Simone Anne Simonsen David A Sinclair Rajat Singh Debasish Sinha Frank A Sinicrope Agnieszka Sirko Parco M Siu Efthimios Sivridis Vojtech Skop Vladimir P Skulachev Ruth S Slack Soraya S Smaili Duncan R Smith Maria S Soengas Thierry Soldati Xueqin Song Anil K Sood Tuck Wah Soong Federica Sotgia Stephen A Spector Claudia D Spies Wolfdieter Springer Srinivasa M Srinivasula Leonidas Stefanis Joan S Steffan Ruediger Stendel Harald Stenmark Anastasis Stephanou Stephan T Stern Cinthya Sternberg Björn Stork Peter Strålfors Carlos S Subauste Xinbing Sui David Sulzer Jiaren Sun Shi-Yong Sun Zhi-Jun Sun Joseph J Y Sung Kuninori Suzuki Toshihiko Suzuki Michele S Swanson Charles Swanton Sean T Sweeney Lai-King Sy Gyorgy Szabadkai Ira Tabas Heinrich Taegtmeyer Marco Tafani Krisztina Takács-Vellai Yoshitaka Takano Kaoru Takegawa Genzou Takemura Fumihiko Takeshita Nicholas J Talbot Kevin S W Tan Keiji Tanaka Kozo Tanaka Daolin Tang Dingzhong Tang Isei Tanida Bakhos A Tannous Nektarios Tavernarakis Graham S Taylor Gregory A Taylor J Paul Taylor Lance S Terada Alexei Terman Gianluca Tettamanti Karin Thevissen Craig B Thompson Andrew Thorburn Michael Thumm FengFeng Tian Yuan Tian Glauco Tocchini-Valentini Aviva M Tolkovsky Yasuhiko Tomino Lars Tönges Sharon A Tooze Cathy Tournier John Tower Roberto Towns Vladimir Trajkovic Leonardo H Travassos Ting-Fen Tsai Mario P Tschan Takeshi Tsubata Allan Tsung Boris Turk Lorianne S Turner Suresh C Tyagi Yasuo Uchiyama Takashi Ueno Midori Umekawa Rika Umemiya-Shirafuji Vivek K Unni Maria I Vaccaro Enza Maria Valente Greet Van den Berghe Ida J van der Klei Wouter van Doorn Linda F van Dyk Marjolein van Egmond Leo A van Grunsven Peter Vandenabeele Wim P Vandenberghe Ilse Vanhorebeek Eva C Vaquero Guillermo Velasco Tibor Vellai Jose Miguel Vicencio Richard D Vierstra Miquel Vila Cécile Vindis Giampietro Viola Maria Teresa Viscomi Olga V Voitsekhovskaja Clarissa von Haefen Marcela Votruba Keiji Wada Richard Wade-Martins Cheryl L Walker Craig M Walsh Jochen Walter Xiang-Bo Wan Aimin Wang Chenguang Wang Dawei Wang Fan Wang Fen Wang Guanghui Wang Haichao Wang 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Yoshikawa Tamotsu Yoshimori Kohki Yoshimoto Ho Jin You Richard J Youle Anas Younes Li Yu Long Yu Seong-Woon Yu Wai Haung Yu Zhi-Min Yuan Zhenyu Yue Cheol-Heui Yun Michisuke Yuzaki Olga Zabirnyk Elaine Silva-Zacarin David Zacks Eldad Zacksenhaus Nadia Zaffaroni Zahra Zakeri Herbert J Zeh Scott O Zeitlin Hong Zhang Hui-Ling Zhang Jianhua Zhang Jing-Pu Zhang Lin Zhang Long Zhang Ming-Yong Zhang Xu Dong Zhang Mantong Zhao Yi-Fang Zhao Ying Zhao Zhizhuang J Zhao Xiaoxiang Zheng Boris Zhivotovsky Qing Zhong Cong-Zhao Zhou Changlian Zhu Wei-Guo Zhu Xiao-Feng Zhu Xiongwei Zhu Yuangang Zhu Teresa Zoladek Wei-Xing Zong Antonio Zorzano Jürgen Zschocke Brian Zuckerbraun

Autophagy 2012 Apr;8(4):445-544

Life Sciences Institute, University of Michigan, Ann Arbor, MI, USA.

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http://dx.doi.org/10.4161/auto.19496DOI Listing
April 2012

Microarray analysis of CA1 pyramidal neurons in a mouse model of tauopathy reveals progressive synaptic dysfunction.

Neurobiol Dis 2012 Feb 7;45(2):751-62. Epub 2011 Nov 7.

Center for Dementia Research, Nathan Kline Institute, Orangeburg, NY 10962, USA.

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http://dx.doi.org/10.1016/j.nbd.2011.10.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3259262PMC
February 2012

Phospholipase d2 ablation ameliorates Alzheimer's disease-linked synaptic dysfunction and cognitive deficits.

J Neurosci 2010 Dec;30(49):16419-28

Department of Pathology and Cell Biology, Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Medical Center, New York, New York 10032, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3004537PMC
December 2010

Lowering beta-amyloid levels rescues learning and memory in a Down syndrome mouse model.

PLoS One 2010 Jun 3;5(6):e10943. Epub 2010 Jun 3.

Laboratory of Molecular and Cellular Neuroscience, The Rockefeller University, New York, New York, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2880593PMC
June 2010

Acceleration and persistence of neurofibrillary pathology in a mouse model of tauopathy following anesthesia.

FASEB J 2009 Aug 11;23(8):2595-604. Epub 2009 Mar 11.

Axe Neurosciences, Centre Hospitalier de l'Université Laval, Université Laval, Québec, Québec, Canada.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2717763PMC
August 2009

Metabolic activity determines efficacy of macroautophagic clearance of pathological oligomeric alpha-synuclein.

Am J Pathol 2009 Aug 23;175(2):736-47. Epub 2009 Jul 23.

Dept of Pathology, Columbia University Medical Center, 630 W168th St Rm 12-461, New York NY 10032, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2716969PMC
August 2009

Age-dependent impairment of cognitive and synaptic function in the htau mouse model of tau pathology.

J Neurosci 2009 Aug;29(34):10741-9

Dominick P. Purpura Department of Neuroscience, Albert Einstein College of Medicine, Bronx, New York 10461, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2760256PMC
August 2009

Inhibition of tau polymerization with a cyanine dye in two distinct model systems.

J Biol Chem 2009 Jul 28;284(31):20830-9. Epub 2009 May 28.

Department of Pathology, Taub Institute, Columbia University and Department of Integrative Neuroscience, New York State Psychiatric Institute, New York, New York 10032, USA.

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http://dx.doi.org/10.1074/jbc.M109.016089DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2742848PMC
July 2009

Structure-activity relationship of cyanine tau aggregation inhibitors.

J Med Chem 2009 Jun;52(11):3539-47

Center for Molecular Neurobiology, Department of Molecular and Cellular Biochemistry, The Ohio State University College of Medicine, Columbus, OH 43210, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2745078PMC
June 2009

Optical visualization of Alzheimer's pathology via multiphoton-excited intrinsic fluorescence and second harmonic generation.

Opt Express 2009 Mar;17(5):3679-89

School of Applied and Engineering Physics, Cornell University, Ithaca, New York 14853, USA.

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http://dx.doi.org/10.1364/oe.17.003679DOI Listing
March 2009

Linking Abeta and tau in late-onset Alzheimer's disease: a dual pathway hypothesis.

Neuron 2008 Nov;60(4):534-42

Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Department of Neurology, Columbia University College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA.

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http://dx.doi.org/10.1016/j.neuron.2008.11.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2692134PMC
November 2008

A technique for serial collection of cerebrospinal fluid from the cisterna magna in mouse.

Authors:
Li Liu Karen Duff

J Vis Exp 2008 Nov 10(21). Epub 2008 Nov 10.

Department of Pathology, Columbia University, USA.

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http://dx.doi.org/10.3791/960DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2762909PMC
November 2008

Is tau aggregation toxic or protective?

J Alzheimers Dis 2008 Aug;14(4):453-7

Taub Institute for Research on Alzheimer's Disease, Department of Pathology, Columbia University, New York, NY, USA.

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http://dx.doi.org/10.3233/jad-2008-14415DOI Listing
August 2008

A transgenic rat that develops Alzheimer's disease-like amyloid pathology, deficits in synaptic plasticity and cognitive impairment.

Neurobiol Dis 2008 Jul 7;31(1):46-57. Epub 2008 Apr 7.

Department of Pathology, Taub Institute for Research on Alzheimer's Disease, Columbia University, Black Building #5-513, 650 West 168th Street, New York, NY 10032, USA.

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July 2008

Increased dopaminergic neuron sensitivity to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in transgenic mice expressing mutant A53T alpha-synuclein.

Neurochem Res 2008 May 13;33(5):902-11. Epub 2007 Nov 13.

Taub Institute on Alzheimer's Disease and Aging, Department of Pathology, Columbia University, Black Bldg 513, 650 W 168th St, New York, NY 10032, USA.

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http://dx.doi.org/10.1007/s11064-007-9533-4DOI Listing
May 2008

Retromer deficiency observed in Alzheimer's disease causes hippocampal dysfunction, neurodegeneration, and Abeta accumulation.

Proc Natl Acad Sci U S A 2008 May 14;105(20):7327-32. Epub 2008 May 14.

Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA.

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http://dx.doi.org/10.1073/pnas.0802545105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2386077PMC
May 2008

New directions for frontotemporal dementia drug discovery.

Alzheimers Dement 2008 Mar 10;4(2):89-93. Epub 2007 Sep 10.

Institute on Aging, Center for Neurodegenerative Disease Research, Department of Pathology and Laboratory, University of Pennsylvania School of Medicine, Philadelphia, PA, USA.

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http://dx.doi.org/10.1016/j.jalz.2007.06.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2352148PMC
March 2008

Cholesterol distribution, not total levels, correlate with altered amyloid precursor protein processing in statin-treated mice.

Neuromolecular Med 2006 ;8(3):319-28

Center for Dementia Research, Nathan S. Kline Institute/New York University, Orangeburg, NY 10962, USA.

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http://dx.doi.org/10.1385/nmm:8:3:319DOI Listing
March 2007

Normal and abnormal tau neurobiology.

Authors:
Karen Duff

Alzheimer Dis Assoc Disord 2006 Oct-Dec;20(4):202-5

Taub Institute, Columbia University, New York State Psychiatric Institute, 650 W168th St, New York, NY 10032, USA.

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http://dx.doi.org/10.1097/01.wad.0000213881.01289.d9DOI Listing
February 2007

Antibody against C-terminal Abeta selectively elevates plasma Abeta.

Neuroreport 2007 Feb;18(3):293-6

Department of Neurology, Georgetown University Medical Center, Washington, DC 20057, USA.

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http://dx.doi.org/10.1097/WNR.0b013e3280148e76DOI Listing
February 2007

The amyloid pathology progresses in a neurotransmitter-specific manner.

Neurobiol Aging 2006 Nov 3;27(11):1644-57. Epub 2005 Nov 3.

Department of Pharmacology and Therapeutics, McGill University, 3655 Sir William Osler Promenade, Montreal, Que., Canada, H3G 1Y6.

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http://dx.doi.org/10.1016/j.neurobiolaging.2005.09.034DOI Listing
November 2006

The effects of ABCA1 on cholesterol efflux and Abeta levels in vitro and in vivo.

J Neurochem 2006 Aug 12;98(3):792-800. Epub 2006 Jun 12.

Department of Neuroscience, Georgetown University Medical Center, Washington, DC 20007, USA.

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August 2006

Using proteomics and network analysis to elucidate the consequences of synaptic protein oxidation in a PS1 + AbetaPP mouse model of Alzheimer's disease.

J Alzheimers Dis 2005 Dec;8(3):227-41

Department of Pharmaceutical Sciences, University of Southern California, Los Angeles, CA 90033, USA.

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http://dx.doi.org/10.3233/jad-2005-8302DOI Listing
December 2005

Dense-core plaques in Tg2576 and PSAPP mouse models of Alzheimer's disease are centered on vessel walls.

Am J Pathol 2005 Aug;167(2):527-43

Department of Molecular Genetics VIB8, Neurodegenerative Brain Diseases Research Group, Molecular Neuropathology Project, University of Antwerp, Universiteitsplein 1, B-2610 Antwerp, Belgium.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1603563PMC
http://dx.doi.org/10.1016/S0002-9440(10)62995-1DOI Listing
August 2005

Untangling memory deficits.

Nat Med 2005 Aug;11(8):826-7

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http://dx.doi.org/10.1038/nm0805-826DOI Listing
August 2005

Inhibition of glycogen synthase kinase-3 by lithium correlates with reduced tauopathy and degeneration in vivo.

Proc Natl Acad Sci U S A 2005 May 2;102(19):6990-5. Epub 2005 May 2.

Center for Dementia Research, Nathan S. Kline Institute, New York University, 140 Old Orangeburg Road, Orangeburg, NY 10962, USA.

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http://dx.doi.org/10.1073/pnas.0500466102DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1088065PMC
May 2005

An Abeta sequestration approach using non-antibody Abeta binding agents.

Curr Alzheimer Res 2005 Apr;2(2):265-8

Department of Neurology, Georgetown University Medical Center, Washington, DC 20057, USA.

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http://dx.doi.org/10.2174/1567205053585774DOI Listing
April 2005

Histological co-localization of iron in Abeta plaques of PS/APP transgenic mice.

Neurochem Res 2005 Feb;30(2):201-5

Center for Advanced Brain Imaging, Nathan Kline Institute for Psychiatric Research, 140 Old Orangeburg Road, Orangeburg, NY 10962, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3959869PMC
http://dx.doi.org/10.1007/s11064-004-2442-xDOI Listing
February 2005

Fibrillar amyloid deposition leads to local synaptic abnormalities and breakage of neuronal branches.

Nat Neurosci 2004 Nov 10;7(11):1181-3. Epub 2004 Oct 10.

Molecular Neurobiology Program, Skirball Institute and Department of Neuroscience and Physiology, New York University School of Medicine, New York, New York 10016, USA.

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http://dx.doi.org/10.1038/nn1335DOI Listing
November 2004

Visualization of beta-amyloid plaques in a transgenic mouse model of Alzheimer's disease using MR microscopy without contrast reagents.

Magn Reson Med 2004 Sep;52(3):538-44

Center for Advanced Brain Imaging, The Nathan Kline Institute, Orangeburg, NY 10962, USA.

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http://dx.doi.org/10.1002/mrm.20196DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3962264PMC
September 2004

Presenilin mutations in familial Alzheimer disease and transgenic mouse models accelerate neuronal lysosomal pathology.

J Neuropathol Exp Neurol 2004 Aug;63(8):821-30

Laboratory for Molecular Neuropathology, Mailman Research Center, McLean Hospital, Belmont, Massachusetts, USA.

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http://dx.doi.org/10.1093/jnen/63.8.821DOI Listing
August 2004

Development of Abeta terminal end-specific antibodies and sensitive ELISA for Abeta variant.

Biochem Biophys Res Commun 2004 Jul;319(3):733-7

Immuno-Biological Laboratories Co., Ltd., Fujioka-shi, Gunma 375-0005, Japan.

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http://dx.doi.org/10.1016/j.bbrc.2004.05.051DOI Listing
July 2004

Mostly separate distributions of CLAC- versus Abeta40- or thioflavin S-reactivities in senile plaques reveal two distinct subpopulations of beta-amyloid deposits.

Am J Pathol 2004 Jul;165(1):273-81

Department of Neuropathology and Neuroscience, Graduate School of Pharmaceutical Sciences, University of Tokyo, 7-3-1 Bunkyo-ku, Hongo, Tokyo 113-0033, Japan.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1618534PMC
http://dx.doi.org/10.1016/s0002-9440(10)63295-6DOI Listing
July 2004

Links between the pathology of Alzheimer's disease and vascular dementia.

Neurochem Res 2004 Jun;29(6):1257-66

Department of Neurology, New York University School of Medicine, New York, New York 10016, USA.

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http://dx.doi.org/10.1023/b:nere.0000023612.66691.e6DOI Listing
June 2004

Transgenic mouse models of Alzheimer's disease: how useful have they been for therapeutic development?

Brief Funct Genomic Proteomic 2004 Apr;3(1):47-59

Nathan Kline Institute, Department of Psychiatry, New York University, 140 Old Orangeburg Road, Orangeburg, NY 10962, USA.

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http://dx.doi.org/10.1093/bfgp/3.1.47DOI Listing
April 2004

Rapid neurofibrillary tangle formation after localized gene transfer of mutated tau.

Am J Pathol 2004 Jan;164(1):347-53

Department of Pharmacology and Therapeutics, Louisiana State University Health Sciences Center, Shreveport, Louisiana 71130, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1602230PMC
http://dx.doi.org/10.1016/S0002-9440(10)63124-0DOI Listing
January 2004

Brain damage results in down-regulation of N-acetylaspartate as a neuronal osmolyte.

Neuromolecular Med 2003 ;3(2):95-104

Nathan S Kline Institute for Psychiatric Research, 140 Old Orangeburg Road, Orangeburg, NY 10962, USA.

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http://link.springer.com/10.1385/NMM:3:2:95
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August 2003

Hyperphosphorylation and aggregation of tau in mice expressing normal human tau isoforms.

J Neurochem 2003 Aug;86(3):582-90

Departments of Neuroscience and Pathology, Albert Einstein College of Medicine, Bronx, New York, USA.

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http://dx.doi.org/10.1046/j.1471-4159.2003.01879.xDOI Listing
August 2003

Detection of Alzheimer's amyloid in transgenic mice using magnetic resonance microimaging.

Magn Reson Med 2003 Aug;50(2):293-302

Skirball Institute of Biomolecular Medicine, New York University School of Medicine, New York, New York 10016, USA.

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http://dx.doi.org/10.1002/mrm.10529DOI Listing
August 2003

Use of in vivo models to study the role of cholesterol in the etiology of Alzheimer's disease.

Neurochem Res 2003 Jul;28(7):979-86

Center for Dementia Research, Nathan S. Kline Institute, Orangeburg, New York 10962, USA.

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http://dx.doi.org/10.1023/a:1023294820218DOI Listing
July 2003

Cdk5 is a key factor in tau aggregation and tangle formation in vivo.

Neuron 2003 May;38(4):555-65

Center for Dementia Research, Nathan S. Kline Institute, New York University, 140 Old Orangeburg Road, Orangeburg, NY 10962, USA.

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http://dx.doi.org/10.1016/s0896-6273(03)00259-9DOI Listing
May 2003

Statin therapy for Alzheimer's disease: will it work?

J Mol Neurosci 2002 Aug-Oct;19(1-2):155-61

Nathan S. Kline Institute for Psychiatric Research, Dementia Research Group, Orangeburg, NY, 10962, USA.

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http://dx.doi.org/10.1007/s12031-002-0026-2DOI Listing
January 2003

Co-localization of cholesterol, apolipoprotein E and fibrillar Abeta in amyloid plaques.

Brain Res Mol Brain Res 2003 Jan;110(1):119-25

Center for Dementia Research, Nathan S. Kline Institute, 140 Old Orangeburg Rd, Orangeburg, NY 10962, USA.

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http://dx.doi.org/10.1016/s0169-328x(02)00647-2DOI Listing
January 2003

Organotypic slice cultures from transgenic mice as disease model systems.

J Mol Neurosci 2002 Dec;19(3):317-20

Nathan Kline Institute and Department of Psychiatry, New York University, 140 Old Orangeburg Rd, Orangeburg, NY 10962, USA.

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http://dx.doi.org/10.1385/JMN:19:3:317DOI Listing
December 2002

Cholesterol in Alzheimer's disease and tauopathy.

Ann N Y Acad Sci 2002 Nov;977:367-75

Center for Dementia Research, Nathan S. Kline Institute, 140 Old Orangeburg Road, Orangeburg, NY 10962, USA.

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http://dx.doi.org/10.1111/j.1749-6632.2002.tb04839.xDOI Listing
November 2002

Imaging brain amyloid of Alzheimer disease in vivo in transgenic mice with an Abeta peptide radiopharmaceutical.

J Cereb Blood Flow Metab 2002 Feb;22(2):223-31

Department of Medicine, UCLA School of Medicine, Los Angeles, California 90024, USA.

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http://journals.sagepub.com/doi/10.1097/00004647-200202000-0
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February 2002