Publications by authors named "Karen A Nolan"

44Publications

The neuronal oxygen-sensing pathway controls postnatal vascularization of the murine brain.

FASEB J 2019 11 30;33(11):12812-12824. Epub 2019 Aug 30.

Department of Cardiovascular Physiology, Institute of Physiology and Pathophysiology, Heidelberg University, Heidelberg, Germany.

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http://dx.doi.org/10.1096/fj.201901385RRDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6902676PMC
November 2019

Negative Cooperativity in NAD(P)H Quinone Oxidoreductase 1 (NQO1).

Chembiochem 2019 11 20;20(22):2841-2849. Epub 2019 Sep 20.

School of Biological Sciences, Queen's University Belfast, Medical Biology Centre, 97 Lisburn Road, Belfast, BT9 7BL, UK.

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http://dx.doi.org/10.1002/cbic.201900313DOI Listing
November 2019

Source and microenvironmental regulation of erythropoietin in the kidney.

Curr Opin Nephrol Hypertens 2018 07;27(4):277-282

Institute of Physiology, University of Zurich, Zurich, and National Center of Competence in Research 'Kidney.CH', Zurich, Switzerland.

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http://dx.doi.org/10.1097/MNH.0000000000000420DOI Listing
July 2018

Neurophysiological Effects of Bitopertin in Schizophrenia.

J Clin Psychopharmacol 2017 Aug;37(4):447-451

From the *Schizophrenia Research Center, Nathan Kline Institute, Orangeburg; †Department of Psychiatry, Columbia University; ‡Department of Psychiatry, New York University School of Medicine; §Graduate Center, City University of New York; and ∥Department of Child and Adolescent Psychiatry, New York University School of Medicine, New York, NY.

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http://Insights.ovid.com/crossref?an=00004714-201708000-0001
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http://dx.doi.org/10.1097/JCP.0000000000000722DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5492956PMC
August 2017

Improvement in mismatch negativity generation during d-serine treatment in schizophrenia: Correlation with symptoms.

Schizophr Res 2018 01 18;191:70-79. Epub 2017 Mar 18.

Schizophrenia Research Center, Nathan Kline Institute, 140 Old Orangeburg Road, Orangeburg, NY 10962, United States; Department of Psychiatry, Columbia University, 1051 Riverside Drive, New York, NY 10032, United States.

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http://dx.doi.org/10.1016/j.schres.2017.02.027DOI Listing
January 2018

Hypoxia: from basic mechanisms to therapeutics - a meeting report on the Keystone and HypoxiaNet Symposium.

Hypoxia (Auckl) 2015 23;3:67-72. Epub 2015 Oct 23.

Institute of Physiology, University of Zürich, Zürich, Switzerland.

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http://dx.doi.org/10.2147/HP.S83240DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5045090PMC
October 2015

Induction of long noncoding RNA MALAT1 in hypoxic mice.

Hypoxia (Auckl) 2015 8;3:45-52. Epub 2015 Oct 8.

Institute of Physiology and Zurich Center for Human Physiology (ZIHP), University of Zurich, Zurich, Switzerland; National Center of Competence in Research "Kidney.CH", Zurich, Switzerland.

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http://dx.doi.org/10.2147/HP.S90555DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5045088PMC
October 2015

Erythropoietin production by PDGFR-β(+) cells.

Pflugers Arch 2016 08 25;468(8):1479-87. Epub 2016 May 25.

Institute of Physiology, University of Regensburg, 93053, Regensburg, Germany.

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http://dx.doi.org/10.1007/s00424-016-1829-2DOI Listing
August 2016

What can the study of first impressions tell us about attitudinal ambivalence and paranoia in schizophrenia?

Psychiatry Res 2016 Apr 13;238:86-92. Epub 2016 Feb 13.

Nathan S. Kline Institute for Psychiatric Research, Orangeburg, NY, USA; Department of Psychiatry, Columbia University, New York, NY, USA.

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http://dx.doi.org/10.1016/j.psychres.2016.02.014DOI Listing
April 2016

Implicit emotion perception in schizophrenia.

J Psychiatr Res 2015 Dec 9;71:112-9. Epub 2015 Oct 9.

Nathan S. Kline Institute for Psychiatric Research, Orangeburg, NY, United States; Department of Psychiatry, Columbia University, New York, NY, United States.

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http://dx.doi.org/10.1016/j.jpsychires.2015.10.001DOI Listing
December 2015

Paricalcitol protects against TGF-β1-induced fibrotic responses in hypoxia and stabilises HIF-α in renal epithelia.

Exp Cell Res 2015 Jan 5;330(2):371-381. Epub 2014 Aug 5.

Diabetes Complications Research Centre, Conway Institute of Biomolecular and Biomedical Research, School of Medicine and Medical Science, University College Dublin, Belfield, Dublin 4, Ireland. Electronic address:

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http://dx.doi.org/10.1016/j.yexcr.2014.07.034DOI Listing
January 2015

The two common polymorphic forms of human NRH-quinone oxidoreductase 2 (NQO2) have different biochemical properties.

FEBS Lett 2014 May 12;588(9):1666-72. Epub 2014 Mar 12.

School of Biological Sciences, Queen's University Belfast, Medical Biology Centre, 97 Lisburn Road, Belfast BT9 7BL, UK. Electronic address:

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http://doi.wiley.com/10.1016/j.febslet.2014.02.063
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http://dx.doi.org/10.1016/j.febslet.2014.02.063DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4045209PMC
May 2014

Lipoxins attenuate renal fibrosis by inducing let-7c and suppressing TGFβR1.

J Am Soc Nephrol 2013 Mar 21;24(4):627-37. Epub 2013 Mar 21.

Diabetes Complications Research Centre, Conway Institute of Biomolecular and Biomedical Research, School of Medicine and Medical Sciences, University College Dublin, Dublin 4, Ireland.

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http://dx.doi.org/10.1681/ASN.2012060550DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3609134PMC
March 2013

Behavioral validation of avolition in schizophrenia.

Schizophr Res 2012 Jul 5;138(2-3):255-61. Epub 2012 Mar 5.

Nathan S. Kline Institute for Psychiatric Research, Orangeburg, NY, United States.

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http://dx.doi.org/10.1016/j.schres.2012.02.018DOI Listing
July 2012

In silico screening reveals structurally diverse, nanomolar inhibitors of NQO2 that are functionally active in cells and can modulate NF-κB signaling.

Mol Cancer Ther 2012 Jan 16;11(1):194-203. Epub 2011 Nov 16.

School of Pharmacy and Pharmaceutical Sciences, University of Manchester and Manchester Cancer Research Centre, Manchester M13 9PT, United Kingdom.

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http://dx.doi.org/10.1158/1535-7163.MCT-11-0543DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3272422PMC
January 2012

Novel inhibitors of NRH:quinone oxidoreductase 2 (NQO2): crystal structures, biochemical activity, and intracellular effects of imidazoacridin-6-ones.

J Med Chem 2011 Oct 13;54(19):6597-611. Epub 2011 Sep 13.

Manchester Interdisciplinary Biocentre, University of Manchester and Manchester Cancer Research Centre, Manchester M13 9PT, U.K.

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http://pubs.acs.org/doi/abs/10.1021/jm200416e
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http://dx.doi.org/10.1021/jm200416eDOI Listing
October 2011

In silico identification and biochemical evaluation of novel inhibitors of NRH:quinone oxidoreductase 2 (NQO2).

Bioorg Med Chem Lett 2010 Dec 21;20(24):7331-6. Epub 2010 Oct 21.

School of Pharmacy and Pharmaceutical Sciences, University of Manchester and Manchester Cancer Research Center, Manchester, UK.

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http://linkinghub.elsevier.com/retrieve/pii/S0960894X1001531
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http://dx.doi.org/10.1016/j.bmcl.2010.10.070DOI Listing
December 2010

Triazoloacridin-6-ones as novel inhibitors of the quinone oxidoreductases NQO1 and NQO2.

Bioorg Med Chem 2010 Jan 21;18(2):696-706. Epub 2009 Dec 21.

School of Pharmacy and Pharmaceutical Sciences, University of Manchester and Manchester Cancer Research Center, Manchester M13 9PT, UK.

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http://dx.doi.org/10.1016/j.bmc.2009.11.059DOI Listing
January 2010

Synthesis and biological evaluation of coumarin-based inhibitors of NAD(P)H: quinone oxidoreductase-1 (NQO1).

J Med Chem 2009 Nov;52(22):7142-56

School of Pharmacy and Pharmaceutical Sciences, University of Manchester, Manchester Cancer Research Center, Manchester, M13 9PT, United Kingdom.

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http://dx.doi.org/10.1021/jm9011609DOI Listing
November 2009

Adolescent cannabis use, psychosis and catechol-O-methyltransferase genotype in African Americans and Caucasians.

Psychiatr Q 2009 Dec;80(4):213-8

Schizophrenia Research Center, Nathan S Kline Institute for Psychiatric Research, 140 Old Orangeburg Road, Orangeburg, NY 10962, USA.

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http://dx.doi.org/10.1007/s11126-009-9108-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2888694PMC
December 2009

Analysis of a promoter polymorphism in the SMDF neuregulin 1 isoform in Schizophrenia.

Neuropsychobiology 2009 10;59(4):205-12. Epub 2009 Jun 10.

Division of Basic Research, Department of Psychiatry and Behavioral Sciences, Albert Einstein College of Medicine, Bronx, NY 10461, USA.

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http://dx.doi.org/10.1159/000223732DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2790772PMC
October 2009

Staff and patient views of the reasons for aggressive incidents: a prospective, incident-based study.

Psychiatr Q 2009 Sep 2;80(3):167-72. Epub 2009 May 2.

Clinical Research Division, Nathan S. Kline Institute for Psychiatric Research, Orangeburg, NY, 10962, USA.

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http://link.springer.com/10.1007/s11126-009-9104-8
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http://dx.doi.org/10.1007/s11126-009-9104-8DOI Listing
September 2009

Atypical antipsychotics, neurocognitive deficits, and aggression in schizophrenic patients.

J Clin Psychopharmacol 2008 Oct;28(5):485-93

Nathan Kline Institute for Psychiatric Research, 140 Old Orangeburg Rd, Orangeburg, NY 10962, USA.

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http://dx.doi.org/10.1097/JCP.0b013e3181855cd6DOI Listing
October 2008

Public-academic partnerships: integrating state psychiatric hospital treatment and clinical research.

Psychiatr Serv 2008 Sep;59(9):958-60

Nathan S. Kline Institute forPsychiatric Research, 140 Old Orangeburg Rd., Orangeburg, NY 10962, USA.

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http://dx.doi.org/10.1176/ps.2008.59.9.958DOI Listing
September 2008

Methodological structure for aggression research.

Psychiatr Q 2008 Dec 15;79(4):293-300. Epub 2008 Jul 15.

New York University School of Medicine, New York, NY, USA.

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http://dx.doi.org/10.1007/s11126-008-9074-2DOI Listing
December 2008

Coumarin-based inhibitors of human NAD(P)H:quinone oxidoreductase-1. Identification, structure-activity, off-target effects and in vitro human pancreatic cancer toxicity.

J Med Chem 2007 Dec 14;50(25):6316-25. Epub 2007 Nov 14.

School of Pharmacy and Pharmaceutical Sciences, University of Manchester, Oxford Road, Manchester, M13 9PT, UK.

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http://dx.doi.org/10.1021/jm070472pDOI Listing
December 2007

Reducing inpatient aggression: does paying attention pay off?

Psychiatr Q 2008 Jun;79(2):91-5

Nathan S Kline Institute for Psychiatric Research, 140 Old Orangeburg Road, Orangeburg, NY 10962, USA.

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http://dx.doi.org/10.1007/s11126-007-9058-7DOI Listing
June 2008

Risperidone alone versus risperidone plus valproate in the treatment of patients with schizophrenia and hostility.

Int Clin Psychopharmacol 2007 Nov;22(6):356-62

Nathan S Kline Institute for Psychiatric Research, Orangeburg, New York 10962, USA.

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http://dx.doi.org/10.1097/YIC.0b013e3281c61bafDOI Listing
November 2007

Gender differences in facial emotion recognition in persons with chronic schizophrenia.

Eur Psychiatry 2007 Mar 29;22(2):116-22. Epub 2006 Nov 29.

Department of General Psychiatry, Medical University Innsbruck, Anichstrasse 35, 6020 Innsbruck, Austria.

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http://linkinghub.elsevier.com/retrieve/pii/S092493380600123
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http://dx.doi.org/10.1016/j.eurpsy.2006.05.003DOI Listing
March 2007

In silico identification and biochemical characterization of novel inhibitors of NQO1.

Bioorg Med Chem Lett 2006 Dec 29;16(24):6246-54. Epub 2006 Sep 29.

School of Pharmacy and Pharmaceutical Sciences, University of Manchester, Oxford Road Manchester M13 9PL, UK.

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http://dx.doi.org/10.1016/j.bmcl.2006.09.015DOI Listing
December 2006

Positive association of schizophrenia to JARID2 gene.

Am J Med Genet B Neuropsychiatr Genet 2007 Jan;144B(1):45-51

Department of Psychiatry, Division of Basic Research, Albert Einstein College of Medicine, Bronx, New York, USA.

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http://dx.doi.org/10.1002/ajmg.b.30386DOI Listing
January 2007

Analysis of polymorphisms in AT-rich domains of neuregulin 1 gene in schizophrenia.

Am J Med Genet B Neuropsychiatr Genet 2006 Jan;141B(1):102-9

Department of Psychiatry, Division of Basic Research, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10461, USA.

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http://dx.doi.org/10.1002/ajmg.b.30242DOI Listing
January 2006

Aggression and psychopathology in treatment-resistant inpatients with schizophrenia and schizoaffective disorder.

J Psychiatr Res 2005 Jan;39(1):109-15

Nathan Kline Institute for Psychiatric Research, 140 Old Orangeburg Road, Orangeburg, NY 10962, USA.

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http://dx.doi.org/10.1016/j.jpsychires.2004.04.010DOI Listing
January 2005

Characteristics of assaultive behavior among psychiatric inpatients.

Psychiatr Serv 2003 Jul;54(7):1012-6

Nathan S. Kline Institute for Psychiatric Research, 140 Old Orangeburg Road, Orangeburg, New York 10962, USA.

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http://dx.doi.org/10.1176/appi.ps.54.7.1012DOI Listing
July 2003

Aggressive behavior in schizophrenia is associated with the low enzyme activity COMT polymorphism: a replication study.

Am J Med Genet B Neuropsychiatr Genet 2003 Jul;120B(1):29-34

Beer Yaakov Mental Health Center, Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.

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http://dx.doi.org/10.1002/ajmg.b.20021DOI Listing
July 2003