Karani S Vimaleswaran

Karani S Vimaleswaran

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Karani S Vimaleswaran

Karani S Vimaleswaran

Publications by authors named "Karani S Vimaleswaran"

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Association of apolipoprotein E gene polymorphisms with blood lipids and their interaction with dietary factors.

Lipids Health Dis 2018 Apr 30;17(1):98. Epub 2018 Apr 30.

Hugh Sinclair Unit of Human Nutrition and Institute for Cardiovascular and Metabolic Research (ICMR), Department of Food and Nutritional Sciences, University of Reading, Whiteknights, PO Box 226, Reading, RG6 6AP, UK.

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http://dx.doi.org/10.1186/s12944-018-0744-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5928585PMC
April 2018

Apolipoprotein E gene polymorphism modifies fasting total cholesterol concentrations in response to replacement of dietary saturated with monounsaturated fatty acids in adults at moderate cardiovascular disease risk.

Lipids Health Dis 2017 Nov 23;16(1):222. Epub 2017 Nov 23.

Hugh Sinclair Unit of Human Nutrition and Institute for Cardiovascular and Metabolic Research (ICMR), Department of Food & Nutritional Sciences, University of Reading, Whiteknights, PO Box 226, Reading, RG6 6AP, UK.

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http://dx.doi.org/10.1186/s12944-017-0606-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5701425PMC
November 2017

Impact of Lipoprotein Lipase Gene Polymorphism, S447X, on Postprandial Triacylglycerol and Glucose Response to Sequential Meal Ingestion.

Int J Mol Sci 2016 Mar 18;17(3):397. Epub 2016 Mar 18.

Hugh Sinclair Unit of Human Nutrition, Department of Food and Nutritional Sciences, University of Reading, Reading RG6 6AP, UK.

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http://dx.doi.org/10.3390/ijms17030397DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4813252PMC
March 2016

Interactions between uncoupling protein 2 gene polymorphisms, obesity and alcohol intake on liver function: a large meta-analysed population-based study.

Eur J Endocrinol 2015 Dec;173(6):863-72

Hugh Sinclair Unit of Human NutritionDepartment of Food and Nutritional Sciences, School of Chemistry, Food and Pharmacy, University of Reading, Whiteknights, PO Box 226, Reading RG6 6AP, UKPopulationPolicy and Practice, UCL Institute of Child Health, London, UKWolfson Institute of Preventive MedicineCentre for Environmental and Preventive Medicine, Queen Mary University of London, London, UK, Departments of CardiologyEpidemiologyUniversity Medical Center Groningen, University of Groningen, Groningen, The NetherlandsUnit of Primary CareOulu University Hospital, Oulu, FinlandFaculty of MedicineCenter for Life Course EpidemiologyDepartment of PsychiatryCenter for Clinical Neuroscience, University of Oulu, Oulu, FinlandDepartment of PsychiatryMedical Research Center, University Hospital of Oulu, Oulu, FinlandDepartment of Epidemiology and BiostatisticsImperial College London, MRC-PHE Centre for Environment and Health, London, UKDepartment of PsychiatryLeiden University Medical Center, Leiden, The NetherlandsDepartment of PsychiatryEMGO Institute of Health and Care Research, Neuroscience Campus Amsterdam, VU University Medical Center, Amsterdam, The NetherlandsBiocenter OuluUniversity of Oulu, Oulu, FinlandDepartment of GeneticsUniversity Medical Center Groningen, University of Groningen, Groningen, The NetherlandsICIN - Netherlands Heart InstituteDurrer Center for Cardiogenetic Research, Utrecht, The NetherlandsBarts and The London School of Medicine and DentistryQueen Mary University of London, Blizard Institute, Newark Street, London, UKCentre for Population Health ResearchSchool of Health Science and Sansom Institute of Health Research, University of South Australia, Adelaide, South Australia, AustraliaSouth Australian Health and Medical Research InstituteAdelaide, South Australia, Australia Hugh Sinclair Unit of Human NutritionDepartment of Food and Nutritional Sciences, School of Chemistry, Food and Pharmacy, University of Reading, Whiteknights, PO Box 226, Readin

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http://www.eje-online.org/content/173/6/863.full.pdf
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http://www.eje-online.org/lookup/doi/10.1530/EJE-15-0839
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http://dx.doi.org/10.1530/EJE-15-0839DOI Listing
December 2015

Association between Mediterranean and Nordic diet scores and changes in weight and waist circumference: influence of FTO and TCF7L2 loci.

Am J Clin Nutr 2014 Oct 6;100(4):1188-97. Epub 2014 Aug 6.

From the Danish Cancer Society Research Center, Copenhagen, Denmark (NR, JH, and AT); the Institute of Preventive Medicine, Bispebjerg and Frederiksberg Hospitals-The Capital Region, Copenhagen, Denmark (LÄ, SCL, and TIAS); the Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, University of Copenhagen, Copenhagen, Denmark (TSA and TIAS); the Copenhagen Prospective Studies on Asthma in Childhood, Health Sciences, University of Copenhagen and Danish Pediatric Asthma Center, Copenhagen University Hospital, Gentofte, Denmark (TSA); the Department of Epidemiology and Biostatistics, School of Public Health, Imperial College, London, United Kingdom (DR); the Instituto de Investigación Sanitaria de Palma, Palma de Mallorca, Spain (DR); the Centro de Investigacíon Biomédica en Red Fisiopatologia de la Obesidad y Nutrición, Mallorca, Spain (DR); the Medical Research Council Epidemiology Unit, University of Cambridge, Cambridge, United Kingdom (KSV, NJW, and RJFL); the Hugh Sinclair Unit of Human Nutrition, Department of Food and Nutritional Sciences, School of Chemistry, Food and Pharmacy, University of Reading, Reading, United Kingdom (KSV); the Section for Epidemiology, Department of Public Health, Aarhus University, Aarhus, Denmark (JNØ); the Cancer Research and Prevention Institute-Istituto per lo Studio e la Prevenzione Oncologica, Florence, Italy (BB and DP); the Center for Nutrition, Prevention and Health Services, National Institute for Public Health and the Environment Bilthoven, Netherlands (JMAB and DLvdA); the Department of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbruecke Arthur-Scheunert-Allee 114-116, Nuthetal, Germany (HB); and the Icahn School of Medicine at Mount Sinai, The Charles Bronfman Institute for Personalized Medicine, The Mindich Child Health and Development Institute, The Genetics of Obesity and Related Metabolic Traits Program, New York, NY (RJFL).

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http://dx.doi.org/10.3945/ajcn.114.089706DOI Listing
October 2014

Association of vitamin D status with arterial blood pressure and hypertension risk: a mendelian randomisation study.

Authors:
Karani S Vimaleswaran Alana Cavadino Diane J Berry Rolf Jorde Aida Karina Dieffenbach Chen Lu Alexessander Couto Alves Hiddo J Lambers Heerspink Emmi Tikkanen Joel Eriksson Andrew Wong Massimo Mangino Kathleen A Jablonski Ilja M Nolte Denise K Houston Tarunveer Singh Ahluwalia Peter J van der Most Dorota Pasko Lina Zgaga Elisabeth Thiering Veronique Vitart Ross M Fraser Jennifer E Huffman Rudolf A de Boer Ben Schöttker Kai-Uwe Saum Mark I McCarthy Josée Dupuis Karl-Heinz Herzig Sylvain Sebert Anneli Pouta Jaana Laitinen Marcus E Kleber Gerjan Navis Mattias Lorentzon Karen Jameson Nigel Arden Jackie A Cooper Jayshree Acharya Rebecca Hardy Olli Raitakari Samuli Ripatti Liana K Billings Jari Lahti Clive Osmond Brenda W Penninx Lars Rejnmark Kurt K Lohman Lavinia Paternoster Ronald P Stolk Dena G Hernandez Liisa Byberg Emil Hagström Håkan Melhus Erik Ingelsson Dan Mellström Osten Ljunggren Ioanna Tzoulaki Stela McLachlan Evropi Theodoratou Carla M T Tiesler Antti Jula Pau Navarro Alan F Wright Ozren Polasek James F Wilson Igor Rudan Veikko Salomaa Joachim Heinrich Harry Campbell Jacqueline F Price Magnus Karlsson Lars Lind Karl Michaëlsson Stefania Bandinelli Timothy M Frayling Catharina A Hartman Thorkild I A Sørensen Stephen B Kritchevsky Bente Lomholt Langdahl Johan G Eriksson Jose C Florez Tim D Spector Terho Lehtimäki Diana Kuh Steve E Humphries Cyrus Cooper Claes Ohlsson Winfried März Martin H de Borst Meena Kumari Mika Kivimaki Thomas J Wang Chris Power Hermann Brenner Guri Grimnes Pim van der Harst Harold Snieder Aroon D Hingorani Stefan Pilz John C Whittaker Marjo-Riitta Järvelin Elina Hyppönen

Lancet Diabetes Endocrinol 2014 Sep 25;2(9):719-29. Epub 2014 Jun 25.

Population, Policy and Practice, UCL Institute of Child Health, London, UK; School of Population Health, Sansom Institute for Health Research, University of South Australia, Adelaide, SA, Australia; South Australian Health and Medical Research Institute, Adelaide, SA, Australia. Electronic address:

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http://dx.doi.org/10.1016/S2213-8587(14)70113-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4582411PMC
September 2014

APOA5 genotype influences the association between 25-hydroxyvitamin D and high density lipoprotein cholesterol.

Atherosclerosis 2013 May 13;228(1):188-92. Epub 2013 Feb 13.

Centre for Paediatric Epidemiology and Biostatistics, MRC Centre of Epidemiology for Child Health, UCL Institute of Child Health, 30 Guilford Street, London WC1N 1EH, UK.

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http://dx.doi.org/10.1016/j.atherosclerosis.2013.02.006DOI Listing
May 2013

Evaluation of genetic markers as instruments for Mendelian randomization studies on vitamin D.

PLoS One 2012 21;7(5):e37465. Epub 2012 May 21.

Centre for Paediatric Epidemiology and Biostatistics, UCL Institute of Child Health, London, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0037465PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3357436PMC
December 2012

A genome-wide association meta-analysis identifies new childhood obesity loci.

Nat Genet 2012 May;44(5):526-31

Center for Applied Genomics, Abramson Research Center, The Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.

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http://dx.doi.org/10.1038/ng.2247DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3370100PMC
May 2012

Uncoupling protein 2 and 3 gene polymorphisms and their association with type 2 diabetes in asian indians.

Diabetes Technol Ther 2011 Jan;13(1):19-25

Madras Diabetes Research Foundation and Dr. Mohan's Diabetes Specialities Centre, Chennai, India.

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http://www.liebertpub.com/doi/10.1089/dia.2010.0091
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http://dx.doi.org/10.1089/dia.2010.0091DOI Listing
January 2011

Lack of association between PCK1 polymorphisms and obesity, physical activity, and fitness in European Youth Heart Study (EYHS).

Obesity (Silver Spring) 2010 Oct 4;18(10):1975-80. Epub 2010 Feb 4.

Institute of Metabolic Science, MRC Epidemiology Unit, Cambridge, UK.

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http://dx.doi.org/10.1038/oby.2010.13DOI Listing
October 2010

Evidence for an association with type 2 diabetes mellitus at the PPARG locus in a South Indian population.

Metabolism 2010 Apr 28;59(4):457-62. Epub 2009 Oct 28.

Madras Diabetes Research Foundation, Gopalapuram, Chennai 600 086, India; Dr Mohan's Diabetes Specialities Centre, Chennai 600 086, India.

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http://dx.doi.org/10.1016/j.metabol.2009.07.034DOI Listing
April 2010

Association of the PPARGC1A gene polymorphism with diabetic nephropathy in an Asian Indian population (CURES-41).

Metab Syndr Relat Disord 2010 Apr;8(2):119-26

Madras Diabetes Research Foundation, and Dr. Mohan's Diabetes Specialities Centre, WHO Collaborating Centre for Noncommunicable Diseases Prevention Control, Gopalapuram, Chennai, India.

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http://www.liebertpub.com/doi/10.1089/met.2009.0040
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http://dx.doi.org/10.1089/met.2009.0040DOI Listing
April 2010

Progress in the genetics of common obesity and type 2 diabetes.

Expert Rev Mol Med 2010 Feb 26;12:e7. Epub 2010 Feb 26.

Medical Research Council Epidemiology Unit, Institute of Metabolic Science, Addenbrooke's Hospital, Hills Road, Cambridge, UK.

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http://dx.doi.org/10.1017/S1462399410001389DOI Listing
February 2010

Absence of association between the INSIG2 gene polymorphism (rs7566605) and obesity in the European Youth Heart Study (EYHS).

Obesity (Silver Spring) 2009 Jul 5;17(7):1453-7. Epub 2009 Feb 5.

MRC Epidemiology Unit, Institute of Metabolic Science, Cambridge, UK.

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http://dx.doi.org/10.1038/oby.2008.650DOI Listing
July 2009

Six new loci associated with body mass index highlight a neuronal influence on body weight regulation.

Authors:
Cristen J Willer Elizabeth K Speliotes Ruth J F Loos Shengxu Li Cecilia M Lindgren Iris M Heid Sonja I Berndt Amanda L Elliott Anne U Jackson Claudia Lamina Guillaume Lettre Noha Lim Helen N Lyon Steven A McCarroll Konstantinos Papadakis Lu Qi Joshua C Randall Rosa Maria Roccasecca Serena Sanna Paul Scheet Michael N Weedon Eleanor Wheeler Jing Hua Zhao Leonie C Jacobs Inga Prokopenko Nicole Soranzo Toshiko Tanaka Nicholas J Timpson Peter Almgren Amanda Bennett Richard N Bergman Sheila A Bingham Lori L Bonnycastle Morris Brown Noël P Burtt Peter Chines Lachlan Coin Francis S Collins John M Connell Cyrus Cooper George Davey Smith Elaine M Dennison Parimal Deodhar Paul Elliott Michael R Erdos Karol Estrada David M Evans Lauren Gianniny Christian Gieger Christopher J Gillson Candace Guiducci Rachel Hackett David Hadley Alistair S Hall Aki S Havulinna Johannes Hebebrand Albert Hofman Bo Isomaa Kevin B Jacobs Toby Johnson Pekka Jousilahti Zorica Jovanovic Kay-Tee Khaw Peter Kraft Mikko Kuokkanen Johanna Kuusisto Jaana Laitinen Edward G Lakatta Jian'an Luan Robert N Luben Massimo Mangino Wendy L McArdle Thomas Meitinger Antonella Mulas Patricia B Munroe Narisu Narisu Andrew R Ness Kate Northstone Stephen O'Rahilly Carolin Purmann Matthew G Rees Martin Ridderstråle Susan M Ring Fernando Rivadeneira Aimo Ruokonen Manjinder S Sandhu Jouko Saramies Laura J Scott Angelo Scuteri Kaisa Silander Matthew A Sims Kijoung Song Jonathan Stephens Suzanne Stevens Heather M Stringham Y C Loraine Tung Timo T Valle Cornelia M Van Duijn Karani S Vimaleswaran Peter Vollenweider Gerard Waeber Chris Wallace Richard M Watanabe Dawn M Waterworth Nicholas Watkins Jacqueline C M Witteman Eleftheria Zeggini Guangju Zhai M Carola Zillikens David Altshuler Mark J Caulfield Stephen J Chanock I Sadaf Farooqi Luigi Ferrucci Jack M Guralnik Andrew T Hattersley Frank B Hu Marjo-Riitta Jarvelin Markku Laakso Vincent Mooser Ken K Ong Willem H Ouwehand Veikko Salomaa Nilesh J Samani Timothy D Spector Tiinamaija Tuomi Jaakko Tuomilehto Manuela Uda André G Uitterlinden Nicholas J Wareham Panagiotis Deloukas Timothy M Frayling Leif C Groop Richard B Hayes David J Hunter Karen L Mohlke Leena Peltonen David Schlessinger David P Strachan H-Erich Wichmann Mark I McCarthy Michael Boehnke Inês Barroso Gonçalo R Abecasis Joel N Hirschhorn

Nat Genet 2009 Jan 14;41(1):25-34. Epub 2008 Dec 14.

Genetic Investigation of ANthropometric Traits Consortium.

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http://dx.doi.org/10.1038/ng.287DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2695662PMC
January 2009

A novel association of a polymorphism in the first intron of adiponectin gene with type 2 diabetes, obesity and hypoadiponectinemia in Asian Indians.

Hum Genet 2008 07 9;123(6):599-605. Epub 2008 May 9.

Madras Diabetes Research Foundation, Dr. Mohan's Diabetes Specialities Centre, WHO Collaborating Centre for Diabetes and ICMR Advanced Centre for Genomics of Diabetes, Chennai, India.

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http://dx.doi.org/10.1007/s00439-008-0506-8DOI Listing
July 2008

Habitual energy expenditure modifies the association between NOS3 gene polymorphisms and blood pressure.

Am J Hypertens 2008 Mar 31;21(3):297-302. Epub 2008 Jan 31.

Medical Research Council Epidemiology Unit, Institute of Metabolic Science, Cambridge, UK.

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http://dx.doi.org/10.1038/ajh.2007.69DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2714087PMC
March 2008

Thr54 allele carriers of the Ala54Thr variant of FABP2 gene have associations with metabolic syndrome and hypertriglyceridemia in urban South Indians.

Metabolism 2006 Sep;55(9):1222-6

Department of Molecular Genetics Madras Diabetes Research Foundation, Gopalapuram, Chennai, 600 086, India.

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http://dx.doi.org/10.1016/j.metabol.2006.05.006DOI Listing
September 2006