Kanti Rai

Kanti Rai

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Kanti Rai

Kanti Rai

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Chronic lymphocytic leukemia (CLL) treatment: So many choices, such great options.

Cancer 2019 May 26;125(9):1432-1440. Epub 2019 Feb 26.

Chronic Lymphocytic Leukemia Research and Treatment Program, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, New Hyde Park, New York.

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http://dx.doi.org/10.1002/cncr.31931DOI Listing
May 2019

Chylothorax in Patients with Chronic Lymphocytic Leukemia: A Case Series.

J Hematol (Brossard) 2018 Jan;7(1):14-18

Department of Medicine Hofstra Northwell School of Medicine, New Hyde Park, NY, USA.

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http://dx.doi.org/10.14740/jh339wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6173329PMC
January 2018

Chronic lymphocytic leukaemia.

Nat Rev Dis Primers 2017 01 19;3:16096. Epub 2017 Jan 19.

CLL Research and Treatment Program, Feinstein Institute for Medical Research, Northwell Health, New Hyde Park, New York, USA.

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http://www.nature.com/articles/nrdp201696
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http://dx.doi.org/10.1038/nrdp.2016.96DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5336551PMC
January 2017

Chronic lymphocytic leukemia immunoglobulins display bacterial reactivity that converges and diverges from auto-/poly-reactivity and IGHV mutation status.

Clin Immunol 2016 Nov 29;172:44-51. Epub 2016 Aug 29.

The Feinstein Institute for Medical Research, Northwell Health, Manhasset, NY, USA; Department of Molecular Medicine, Hofstra Northwell School of Medicine, Hempstead, NY, USA. Electronic address:

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http://dx.doi.org/10.1016/j.clim.2016.08.020DOI Listing
November 2016

Treatment outcomes and secondary cancer incidence in young patients with hairy cell leukaemia.

Br J Haematol 2016 Nov 28;175(3):402-409. Epub 2016 Jun 28.

Leukemia Service, Memorial Sloan Kettering Cancer Center, Weill Cornell Medical College, New York, NY, USA.

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http://dx.doi.org/10.1111/bjh.14207DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5539949PMC
November 2016

Chronic lymphocytic leukemia cells diversify and differentiate in vivo via a nonclassical Th1-dependent, Bcl-6-deficient process.

JCI Insight 2016 Apr;1(4)

The Feinstein Institute for Medical Research, Northwell Health, Manhasset, New York, USA.; Department of Medicine, Hofstra Northwell School of Medicine, Manhasset, New York, USA.; Department of Molecular Medicine, Hofstra Northwell School of Medicine, Hempstead, New York, USA.

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http://dx.doi.org/10.1172/jci.insight.86288DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4855875PMC
April 2016

Chronic lymphocytic leukemia (CLL)-Then and now.

Am J Hematol 2016 Mar;91(3):330-40

Department of Internal Medicine, University of Texas Medical School at Houston, Texas.

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http://dx.doi.org/10.1002/ajh.24282DOI Listing
March 2016

Targeting Mutant BRAF in Relapsed or Refractory Hairy-Cell Leukemia.

N Engl J Med 2015 Oct 9;373(18):1733-47. Epub 2015 Sep 9.

From the Institute of Hematology, Department of Medicine, and Centro di Ricerca Emato-Oncologico (CREO), University of Perugia, and Ospedale Santa Maria della Misericordia, Perugia (E.T., L.D.C., F.F., S.A., M.C., M.P.M., B.F.), the Department of Experimental, Diagnostic, and Specialty Medicine, Units of Hematology and Hematopathology, Bologna University School of Medicine, Bologna (A.B., S.A.P., P.L.Z.), Hematology Unit, Centro Trapianti e Terapie Cellulari Carlo Melzi, Dipartimento di Science Mediche Sperimentali e Cliniche, Azienda Ospedaliero Universitaria, Udine (F.Z.), the Department of Cellular Biotechnologies and Hematology, Division of Hematology, Sapienza University, Rome (A.P., R.F.), the Hematology and Bone Marrow Transplant Unit, Azienda Ospedaliera Regionale San Carlo, Potenza (M.C.), the Division of Hematology, Department of Translational Medicine, Amedeo Avogadro University of Eastern Piedmont, Novara (D.R.), Hematology Unit, Ospedale Ferrarotto, Catania (G.M.), the Department of Onco-Hematology, Fondazione IRCCS, Policlinico San Matteo, Pavia (M.V.), Hematology Unit, Spedali Civili, Brescia (A. Anastasia), the Department of Medicine, Section of Hematology, University of Verona, Verona (A. Ambrosetti), Onco-Hematology Unit, Fondazione di Ricerca e Cura S.S. Giovanni Paolo II, Campobasso (V.F.), Institute of Hematology 1, IRCCS, Azienda Ospedaliero Universitaria San Martino-Istituto Nazionale per la Ricerca sul Cancro, Genoa (A.M.C.), the Department of Hematology, Azienda Ospedaliero Universitaria Ospedali Riuniti, Ancona (P.L.), and the Hematology and Bone Marrow Transplant Unit, Azienda Ospedaliera Papa Giovanni XXIII, Bergamo (A.R.) - all in Italy; Leukemia Service (J.H.P., S.S.C., R.L.L., O.A-W., M.S.T.,) and Dermatology Service (M.E.L.), the Department of Medicine, Human Oncology and Pathogenesis Program (S.S., Y.R.C., E.K., R.L.L., C.Y.P., M.F.B., O.A-W.), the Departments of Epidemiology and Biostatistics (S.D.), Pathology (C.Y.P.), and Pharmaco

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http://dx.doi.org/10.1056/NEJMoa1506583DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4811324PMC
October 2015

TLR-9 and IL-15 Synergy Promotes the In Vitro Clonal Expansion of Chronic Lymphocytic Leukemia B Cells.

J Immunol 2015 Aug 1;195(3):901-23. Epub 2015 Jul 1.

The Feinstein Institute for Medical Research, North Shore-Long Island Jewish Health System, Manhasset, NY 11030; Department of Molecular Medicine, Hofstra North Shore-LIJ School of Medicine, Hempstead, NY 11549; Department of Medicine, North Shore University Hospital-Long Island Jewish Medical Center, Manhasset, NY; and Department of Medicine, Hofstra North Shore-LIJ School of Medicine, Hempstead, NY.

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http://www.jimmunol.org/content/early/2015/07/01/jimmunol.14
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http://www.jimmunol.org/cgi/doi/10.4049/jimmunol.1403189
Publisher Site
http://dx.doi.org/10.4049/jimmunol.1403189DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4505957PMC
August 2015

In Support of a Patient-Driven Initiative and Petition to Lower the High Price of Cancer Drugs.

Authors:
Ayalew Tefferi Hagop Kantarjian S Vincent Rajkumar Lawrence H Baker Jan L Abkowitz John W Adamson Ranjana Hira Advani James Allison Karen H Antman Robert C Bast John M Bennett Edward J Benz Nancy Berliner Joseph Bertino Ravi Bhatia Smita Bhatia Deepa Bhojwani Charles D Blanke Clara D Bloomfield Linda Bosserman Hal E Broxmeyer John C Byrd Fernando Cabanillas George Peter Canellos Bruce A Chabner Asher Chanan-Khan Bruce Cheson Bayard Clarkson Susan L Cohn Gerardo Colon-Otero Jorge Cortes Steven Coutre Massimo Cristofanilli Walter J Curran George Q Daley Daniel J DeAngelo H Joachim Deeg Lawrence H Einhorn Harry P Erba Francisco J Esteva Elihu Estey Isaiah J Fidler James Foran Stephen Forman Emil Freireich Charles Fuchs James N George Morie A Gertz Sergio Giralt Harvey Golomb Peter Greenberg Jordan Gutterman Robert I Handin Samuel Hellman Paulo Marcelo Hoff Ronald Hoffman Waun Ki Hong Mary Horowitz Gabriel N Hortobagyi Clifford Hudis Jean Pierre Issa Bruce Evan Johnson Philip W Kantoff Kenneth Kaushansky David Khayat Fadlo R Khuri Thomas J Kipps Margaret Kripke Robert A Kyle Richard A Larson Theodore S Lawrence Ross Levine Michael P Link Scott M Lippman Sagar Lonial Gary H Lyman Maurie Markman John Mendelsohn Neal J Meropol Yoav Messinger Therese M Mulvey Susan O'Brien Roman Perez-Soler Raphael Pollock Josef Prchal Oliver Press Jerald Radich Kanti Rai Saul A Rosenberg Jacob M Rowe Hope Rugo Carolyn D Runowicz Brenda M Sandmaier Alan Saven Andrew I Schafer Charles Schiffer Mikkael A Sekeres Richard T Silver Lillian L Siu David P Steensma F Marc Stewart Wendy Stock Richard Stone Rainer Storb Louise C Strong Martin S Tallman Michael Thompson Naoto T Ueno Richard A Van Etten Julie M Vose Peter H Wiernik Eric P Winer Anas Younes Andrew D Zelenetz Charles A LeMaistre

Mayo Clin Proc 2015 Aug 23;90(8):996-1000. Epub 2015 Jul 23.

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http://dx.doi.org/10.1016/j.mayocp.2015.06.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5365030PMC
August 2015

Therapeutic potential of new B cell-targeted agents in the treatment of elderly and unfit patients with chronic lymphocytic leukemia.

Authors:
Kanti R Rai

J Hematol Oncol 2015 Jul 14;8:85. Epub 2015 Jul 14.

Hofstra North Shore-LIJ School of Medicine and the North Shore-LIJ Cancer Institute, Lake Success, NY, USA.

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http://dx.doi.org/10.1186/s13045-015-0165-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4522086PMC
July 2015

Augmenting NF-κB in poor-risk CLL: A general paradigm for other cancers?

J Exp Med 2015 Jun;212(6):830-1

Cancer Center at Cold Spring Harbor Laboratory; Feinstein Institute for Medical Research, North Shore-LIJ Health System

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http://dx.doi.org/10.1084/jem.2126insight4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4451126PMC
June 2015

Lenalidomide and rituximab for the initial treatment of patients with chronic lymphocytic leukemia: a multicenter clinical-translational study from the chronic lymphocytic leukemia research consortium.

J Clin Oncol 2014 Jul 27;32(19):2067-73. Epub 2014 May 27.

Danelle F. James, Januario E. Castro, Andrew Greaves, Laura Z. Rassenti, Thomas J. Kipps, Moores Cancer Center, University of California San Diego, La Jolla, CA; Lillian Werner, Jennifer R. Brown, Donna Neuberg, Dana-Farber Cancer Institute, Boston, MA; William G. Wierda, MD Anderson Cancer Center, The University of Texas, Houston, TX; Jacqueline C. Barrientos, Kanti R. Rai, North Shore-Long Island Jewish Health System, New Hyde Park, NY; Amy J. Johnson, The Ohio State University, Columbus, OH.

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http://dx.doi.org/10.1200/JCO.2013.51.5890DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4067945PMC
July 2014

Movement toward optimization of CLL therapy.

N Engl J Med 2014 Mar;370(12):1160-2

From the Hofstra North Shore-LIJ School of Medicine and the North Shore-LIJ Cancer Institute - both in Lake Success, NY; and the Feinstein Institute for Medical Research, Manhasset, NY.

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http://dx.doi.org/10.1056/NEJMe1400599DOI Listing
March 2014

Ibrutinib: a novel Bruton's tyrosine kinase inhibitor with outstanding responses in patients with chronic lymphocytic leukemia.

Leuk Lymphoma 2013 Aug;54(8):1817-20

Hofstra North Shore-LIJ School of Medicine, Department of Medicine, Division Hematology-Oncology, CLL Research and Treatment Program , 410 Lakeville Road Suite 212, New Hyde Park, NY 11042, USA.

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http://dx.doi.org/10.3109/10428194.2013.796049DOI Listing
August 2013

Peptides that bind specifically to an antibody from a chronic lymphocytic leukemia clone expressing unmutated immunoglobulin variable region genes.

Mol Med 2013 Aug 28;19:245-52. Epub 2013 Aug 28.

The Feinstein Institute for Medical Research, North Shore-LIJ Health System, Manhasset, New York 11030, USA.

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http://dx.doi.org/10.2119/molmed.2013.00082DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3769532PMC
August 2013

Overview of recent developments in chronic lymphocytic leukemia.

South Asian J Cancer 2012 Oct;1(2):84-9

Department of Medicine, Long Island Jewish Medical Center New Hyde Park and Hofstra North Shore-LIJ School of Medicine, Hempstead, NY, USA.

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http://dx.doi.org/10.4103/2278-330X.103721DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3876608PMC
October 2012

Novel targeted agents and the need to refine clinical end points in chronic lymphocytic leukemia.

J Clin Oncol 2012 Aug 9;30(23):2820-2. Epub 2012 Jul 9.

Lombardi Comprehensive Cancer Center, Georgetown University Hospital, Washington, DC, USA.

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http://dx.doi.org/10.1200/JCO.2012.43.3748DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3410400PMC
August 2012

Advances in the clinical staging of chronic lymphocytic leukemia.

Clin Chem 2011 Dec 11;57(12):1771-2. Epub 2011 Aug 11.

CLL Research and Treatment Program, The Feinstein Institute for Medical Research, North Shore-LIJ Health System, New Hyde Park, NY, USa.

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http://dx.doi.org/10.1373/clinchem.2010.159004DOI Listing
December 2011

Identification of outcome-correlated cytokine clusters in chronic lymphocytic leukemia.

Blood 2011 Nov 12;118(19):5201-10. Epub 2011 Sep 12.

The Feinstein Institute for Medical Research, North Shore-Long Island Jewish Health System, Manhasset, NY, USA.

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http://dx.doi.org/10.1182/blood-2011-03-342436DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3217404PMC
November 2011

Accurate reporting of adverse events in chronic lymphocytic leukemia and non-Hodgkin lymphoma.

Clin Adv Hematol Oncol 2011 Jul;9(7 Suppl 15):1-11

Georgetown University Hospital, Lombardi Comprehensive Cancer Center, Washington, DC, USA.

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July 2011

Alemtuzumab maintenance may safely prolong chemotherapy-free intervals in chronic lymphocytic leukemia.

Med Oncol 2011 Jun 17;28(2):532-8. Epub 2010 Mar 17.

Department of Medicine, Division of Hematology and Oncology, Long Island Jewish Medical Center, CLL Research and Treatment Center, New Hyde Park, NY, USA,

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http://dx.doi.org/10.1007/s12032-010-9478-3DOI Listing
June 2011

Historical treatments of in hairy cell leukemia, splenectomy and interferon: past and current uses.

Leuk Lymphoma 2011 Jun;52 Suppl 2:18-20

Division of Hematology, Department of Medicine, Mayo Clinic College of Medicine and Mayo Foundation, Rochester, MN 55905, USA.

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http://dx.doi.org/10.3109/10428194.2011.573033DOI Listing
June 2011

Fludarabine versus chlorambucil: is the debate over?

Clin Lymphoma Myeloma Leuk 2011 Jun 7;11 Suppl 1:S7-9. Epub 2011 May 7.

Long Island Jewish Medical Center, Hofstra University School of Medicine, New York, NY 11042, USA.

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http://dx.doi.org/10.1016/j.clml.2011.04.007DOI Listing
June 2011

The challenge of treating complex autoimmune cytopenias in chronic lymphocytic leukemia.

Leuk Lymphoma 2010 Apr;51(4):574-5

Hematology-Oncology, Long Island Jewish Medical Center, New Hyde Park, NY 11040, USA.

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http://dx.doi.org/10.3109/10428191003754632DOI Listing
April 2010

Where do we go from here?

Authors:
Kanti R Rai

Best Pract Res Clin Haematol 2010 Mar;23(1):167-8

Albert Einstein College of Medicine, Division of Hematology-Oncology, Long Island Jewish Medical Center, 270-05 76th Avenue, New Hyde Park, NY 11040, USA.

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http://dx.doi.org/10.1016/j.beha.2010.01.002DOI Listing
March 2010

Diagnosing and treating chronic lymphocytic leukemia in 2009.

Oncology (Williston Park) 2009 Nov;23(12):1030-7

Department of Medicine, Division of Hematology-Oncology, Albert Einstein College of Medicine, Long Island Jewish Medical Center, New Hyde Park, New York, USA.

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November 2009

Chronic lymphocytic leukemia antibodies with a common stereotypic rearrangement recognize nonmuscle myosin heavy chain IIA.

Blood 2008 Dec 23;112(13):5122-9. Epub 2008 Sep 23.

The Feinstein Institute for Medical Research, North Shore-Long Island Jewish (LIJ) Health System, Manhasset, NY, USA.

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http://dx.doi.org/10.1182/blood-2008-06-162024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2597608PMC
December 2008

The natural history of CLL and new prognostic markers.

Authors:
Kanti R Rai

Clin Adv Hematol Oncol 2008 May;6(5):4-5; quiz 10-2

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May 2008

Alemtuzumab in the up-front setting.

Ther Clin Risk Manag 2008 Apr;4(2):459-64

Long Island Jewish Medical Center New Hyde Park, NY, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2504068PMC
http://dx.doi.org/10.2147/tcrm.s1979DOI Listing
April 2008

Depression, anxiety and quality of life in a chronic lymphocytic leukemia cohort.

Gen Hosp Psychiatry 2007 May-Jun;29(3):251-6

Department of Psychiatry and Behavioral Sciences, Memorial Sloan-Kettering Cancer Center, New York, NY 10022, USA.

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http://dx.doi.org/10.1016/j.genhosppsych.2007.01.014DOI Listing
January 2008

CD38 expression labels an activated subset within chronic lymphocytic leukemia clones enriched in proliferating B cells.

Blood 2007 Nov 7;110(9):3352-9. Epub 2007 Aug 7.

Laboratory of Experimental Immunology, The Feinstein Institute for Medical Research, North Shore-Long Island Jewish (LIJ) Health System, 350 Community Drive, Manhasset, NY 11030, USA.

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http://dx.doi.org/10.1182/blood-2007-04-083832DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2200908PMC
November 2007

Introduction: Chronic lymphocytic leukemia in perspective.

Authors:
Kanti R Rai

Best Pract Res Clin Haematol 2007 Sep;20(3):363-5

Division of Hematology-Oncology, Long Island Jewish Med Center, New Hyde Park, NY 11040, USA.

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http://dx.doi.org/10.1016/j.beha.2007.03.008DOI Listing
September 2007

Eugene P. Cronkite--The man and his science.

Exp Hematol 2007 Apr;35(4 Suppl 1):5-7

Bridgeport Hospital and Yale University School of Medicine, Bridgeport, CT 06610, USA.

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http://dx.doi.org/10.1016/j.exphem.2007.01.005DOI Listing
April 2007

Pathophysiologic mechanisms of chronic lymphocytic leukemia and their application to therapy.

Authors:
Kanti R Rai

Exp Hematol 2007 Apr;35(4 Suppl 1):134-6

Division of Hematology-Oncology, Long Island Jewish Medical Center, New Hyde Park, NY 11040, USA.

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http://dx.doi.org/10.1016/j.exphem.2007.01.021DOI Listing
April 2007

Chronic lymphocytic leukemia: current and emerging treatment approaches.

Clin Adv Hematol Oncol 2006 Nov;4(11 Suppl 22):1-10; quiz 11-2

Mayo Clinic College of Medicine, Rochester, Minn, USA.

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November 2006

Novel therapeutic strategies with alemtuzumab for chronic lymphocytic leukemia.

Authors:
Kanti R Rai

Semin Oncol 2006 Apr;33(2 Suppl 5):S15-22

Division of Hematology/Oncology, Long Island Jewish Medical Center, New Hyde Park, NY 11040, USA.

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http://dx.doi.org/10.1053/j.seminoncol.2006.01.025DOI Listing
April 2006

Dendritic cells from chronic lymphocytic leukemia patients are normal regardless of Ig V gene mutation status.

Mol Med 2004 Jul-Dec;10(7-12):96-103

The Laboratory of Experimental Immunology, Institute for Medical Research, North Shore-LIJ Health System, Manhasset, New York, USA.

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http://dx.doi.org/10.2119/2005-00011.MessmerDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1431371PMC
March 2006

Evolution of treatment strategies in chronic lymphocytic leukemia. Part 2 of a 3-Part series: Advances in the treatment of hematologic malignancies.

Clin Adv Hematol Oncol 2005 Aug;3(8):1-10; quiz 11-2

University of Texas M. D. Anderson Cancer Center, Houston, TX, USA.

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August 2005

Malignant pleural effusions in lymphoproliferative disorders.

Leuk Lymphoma 2005 Jul;46(7):1039-44

Saskatoon Cancer Center, University of Saskatchewan, Saskatoon, SK, Canada.

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http://dx.doi.org/10.1080/00268970500096616DOI Listing
July 2005