Kan Chen

Kan Chen

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Procyanidin B2 inhibits the activation of hepatic stellate cells and angiogenesis via the Hedgehog pathway during liver fibrosis.

J Cell Mol Med 2019 Sep 21;23(9):6479-6493. Epub 2019 Jul 21.

Department of Gastroenterology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, China.

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http://dx.doi.org/10.1111/jcmm.14543DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6714206PMC
September 2019

Long-term changes in nutrient regimes and their ecological effects in the Bohai Sea, China.

Mar Pollut Bull 2019 Sep 11;146:562-573. Epub 2019 Jul 11.

The First Institute of Oceanography, Ministry of Natural Resources, Qingdao 266061, China.

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http://dx.doi.org/10.1016/j.marpolbul.2019.07.011DOI Listing
September 2019

Quercetin shows anti-tumor effect in hepatocellular carcinoma LM3 cells by abrogating JAK2/STAT3 signaling pathway.

Cancer Med 2019 Aug 5;8(10):4806-4820. Epub 2019 Jul 5.

Department of Gastroenterology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, China.

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http://dx.doi.org/10.1002/cam4.2388DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6712453PMC
August 2019

Successful endoscopic submucosal dissection of a large cavernous hemangioma in the colon.

Endoscopy 2019 Jul 12;51(7):E195-E196. Epub 2019 Apr 12.

Department of Gastroenterology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, China.

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http://www.thieme-connect.de/DOI/DOI?10.1055/a-0875-3519
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http://dx.doi.org/10.1055/a-0875-3519DOI Listing
July 2019

Building on the success of osimertinib: achieving CNS exposure in oncology drug discovery.

Drug Discov Today 2019 05 30;24(5):1067-1073. Epub 2019 Jan 30.

DMPK, Oncology, IMED Biotech Unit, AstraZeneca, Cambridge, UK.

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https://linkinghub.elsevier.com/retrieve/pii/S13596446183048
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http://dx.doi.org/10.1016/j.drudis.2019.01.015DOI Listing
May 2019

Corrigendum to 'Conserved signaling pathways underlying heterotopic ossification' [Bone, 109, April 2018, 43-48].

Bone 2019 May 28;122:254. Epub 2019 Feb 28.

School of Basic Medical Sciences, Anhui Medical University, Hefei 230032, China; Department of Medical Laboratory Science, Bengbu Medical College, Bengbu 233030, China; Department of Neurology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA. Electronic address:

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http://dx.doi.org/10.1016/j.bone.2019.02.023DOI Listing
May 2019

Sodium butyrate and panobinostat induce apoptosis of chronic myeloid leukemia cells via multiple pathways.

Mol Genet Genomic Med 2019 05 19;7(5):e613. Epub 2019 Mar 19.

College of Life Sciences, Zhejiang Sci-Tech University, Hangzhou, China.

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http://dx.doi.org/10.1002/mgg3.613DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6503025PMC
May 2019

PKM2 is the target of proanthocyanidin B2 during the inhibition of hepatocellular carcinoma.

J Exp Clin Cancer Res 2019 May 17;38(1):204. Epub 2019 May 17.

Department of Gastroenterology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, NO. 301, Middle Yanchang Road, Jing'an District, Shanghai, 200072, China.

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http://dx.doi.org/10.1186/s13046-019-1194-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6525465PMC
May 2019

The Protective Effects of Levo-Tetrahydropalmatine on ConA-Induced Liver Injury Are via TRAF6/JNK Signaling.

Mediators Inflamm 2018 4;2018:4032484. Epub 2018 Dec 4.

Department of Gastroenterology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai 200072, China.

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http://dx.doi.org/10.1155/2018/4032484DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6304924PMC
April 2019

The differences between gonadal and extra-gonadal malignant teratomas in both genders and the effects of chemotherapy.

BMC Cancer 2019 Apr 30;19(1):408. Epub 2019 Apr 30.

Department of Informatics, Discovery & Analytical Solutions, PerkinElmer, Shanghai, No.1670, Zhang Heng Road, Zhangjiang Hi-Tech Park, Shanghai, 201203, China.

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http://dx.doi.org/10.1186/s12885-019-5598-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6492338PMC
April 2019

Action and clinical significance of CCAAT/enhancer-binding protein delta in hepatocellular carcinoma.

Carcinogenesis 2019 03;40(1):155-163

Department of Gastroenterology and Hepatology, Erasmus MC-University Medical Center, Gravendijkwal, NL, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1093/carcin/bgy130DOI Listing
March 2019

Alleviation of hepatic fibrosis and autophagy via inhibition of transforming growth factor-β1/Smads pathway through shikonin.

J Gastroenterol Hepatol 2019 Jan 10;34(1):263-276. Epub 2018 Jul 10.

Department of Gastroenterology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, China.

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http://dx.doi.org/10.1111/jgh.14299DOI Listing
January 2019

Dichotomal functions of phosphorylated and unphosphorylated STAT1 in hepatocellular carcinoma.

J Mol Med (Berl) 2019 Jan 19;97(1):77-88. Epub 2018 Nov 19.

Department of Gastroenterology and Hepatology, Erasmus MC-University Medical Center, Room Na-617, 's-Gravendijkwal 230, 3015CE, Rotterdam, The Netherlands.

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http://link.springer.com/10.1007/s00109-018-1717-7
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http://dx.doi.org/10.1007/s00109-018-1717-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326978PMC
January 2019

Advancing the understanding of NAFLD to hepatocellular carcinoma development: From experimental models to humans.

Biochim Biophys Acta Rev Cancer 2019 01 5;1871(1):117-125. Epub 2018 Dec 5.

College of Life Sciences, Zhejiang Sci-Tech University, Hangzhou, China; Biomedical Research Center, Northwest Minzu University, Lanzhou, China; Department of Gastroenterology and Hepatology, Erasmus MC-University Medical Center, Rotterdam, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.bbcan.2018.11.005DOI Listing
January 2019

BMP-dependent, injury-induced stem cell niche as a mechanism of heterotopic ossification.

Stem Cell Res Ther 2019 Jan 11;10(1):14. Epub 2019 Jan 11.

School of Basic Medical Sciences, Anhui Medical University, 81 Meishan road, Hefei, 230032, China.

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http://dx.doi.org/10.1186/s13287-018-1107-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6329163PMC
January 2019

Intraluminal pressure triggers myogenic response via activation of calcium spark and calcium-activated chloride channel in rat renal afferent arteriole.

Am J Physiol Renal Physiol 2018 12 8;315(6):F1592-F1600. Epub 2018 Aug 8.

Division of Pulmonary and Critical Care Medicine, Johns Hopkins University School of Medicine , Baltimore, Maryland.

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https://www.physiology.org/doi/10.1152/ajprenal.00239.2018
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http://dx.doi.org/10.1152/ajprenal.00239.2018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6336985PMC
December 2018

Identification of mundoserone by zebrafish screening as a natural product with anti-angiogenic activity.

Exp Ther Med 2018 Dec 17;16(6):4562-4568. Epub 2018 Sep 17.

Department of Cardiology, Shanghai Ninth People's Hospital Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai 200011, P.R. China.

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http://www.spandidos-publications.com/10.3892/etm.2018.6748
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http://dx.doi.org/10.3892/etm.2018.6748DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6257818PMC
December 2018

Accuracy of Virtual Surgical Planning in Treatment of Temporomandibular Joint Ankylosis Using Distraction Osteogenesis: Comparison of Planned and Actual Results.

J Oral Maxillofac Surg 2018 11 7;76(11):2422.e1-2422.e20. Epub 2018 Aug 7.

Professor, State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, Department of Oral and Maxillofacial Surgery, West China Hospital of Stomatology, Sichuan, China. Electronic address:

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http://dx.doi.org/10.1016/j.joms.2018.07.003DOI Listing
November 2018

Salidroside ameliorates autophagy and activation of hepatic stellate cells in mice via NF-κB and TGF-β1/Smad3 pathways.

Drug Des Devel Ther 2018 22;12:1837-1853. Epub 2018 Jun 22.

Department of Gastroenterology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, China.

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http://dx.doi.org/10.2147/DDDT.S162950DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6021006PMC
October 2018

Randomized controlled clinical trial of polyethylene glycol recombinant human granulocyte colony-stimulating factor in the treatment of neutropenia after chemotherapy for breast cancer.

Cancer Chemother Pharmacol 2018 10 24;82(4):607-613. Epub 2018 Jul 24.

Department of Medical Oncology, Fujian Cancer Hospital, Fujian Medical University Cancer Hospital, The Teaching Hospital, Fujian University of Traditional Chinese Medicine, Fuzhou, 350014, Fujian, China.

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http://dx.doi.org/10.1007/s00280-018-3639-zDOI Listing
October 2018

Data-Driven Design of Ecofriendly Thermoelectric High-Entropy Sulfides.

Inorg Chem 2018 Oct 26;57(20):13027-13033. Epub 2018 Sep 26.

School of Engineering and Materials Science , Queen Mary University of London , London E1 4NS , United Kingdom.

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http://dx.doi.org/10.1021/acs.inorgchem.8b02379DOI Listing
October 2018

Isorhamnetin: A hepatoprotective flavonoid inhibits apoptosis and autophagy via P38/PPAR-α pathway in mice.

Biomed Pharmacother 2018 Jul 24;103:800-811. Epub 2018 Apr 24.

Department of Gastroenterology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai 200072, China. Electronic address:

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http://dx.doi.org/10.1016/j.biopha.2018.04.016DOI Listing
July 2018

Fucosterol Protects against Concanavalin A-Induced Acute Liver Injury: Focus on P38 MAPK/NF-B Pathway Activity.

Gastroenterol Res Pract 2018 17;2018:2824139. Epub 2018 Jul 17.

Department of Gastroenterology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai 200072, China.

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http://dx.doi.org/10.1155/2018/2824139DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6079550PMC
July 2018

Salidroside mediates apoptosis and autophagy inhibition in concanavalin A-induced liver injury.

Exp Ther Med 2018 Jun 12;15(6):4599-4614. Epub 2018 Apr 12.

Department of Gastroenterology, Shanghai Tenth People's Hospital, Affiliated to Tongji University School of Medicine, Shanghai 200072, P.R. China.

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http://dx.doi.org/10.3892/etm.2018.6053DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5958679PMC
June 2018

SHP2-Mediated Signal Networks in Stem Cell Homeostasis and Dysfunction.

Stem Cells Int 2018 10;2018:8351374. Epub 2018 Jun 10.

School of Basic Medical Sciences, Anhui Medical University, 81 Meishan Road, Hefei 230022, China.

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http://dx.doi.org/10.1155/2018/8351374DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6015663PMC
June 2018

Allicin attenuates lipopolysaccharide‑induced acute lung injury in neonatal rats via the PI3K/Akt pathway.

Mol Med Rep 2018 May 7;17(5):6777-6783. Epub 2018 Mar 7.

Department of Critical Care Medicine, The Second Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu 221006, P.R. China.

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http://dx.doi.org/10.3892/mmr.2018.8693DOI Listing
May 2018

Conserved signaling pathways underlying heterotopic ossification.

Bone 2018 04 25;109:43-48. Epub 2017 Apr 25.

School of Basic Medical Sciences, Anhui Medical University, Hefei 230032, China; Department of Medical Laboratory Science, Bengbu Medical College, Bengbu 233030, China; Department of Neurology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA. Electronic address:

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http://dx.doi.org/10.1016/j.bone.2017.04.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5801212PMC
April 2018

Gli1-labeled adult mesenchymal stem/progenitor cells and hedgehog signaling contribute to endochondral heterotopic ossification.

Bone 2018 04 21;109:71-79. Epub 2017 Jun 21.

School of Basic Medical Sciences, Anhui Medical University, 81 Meishan road, Hefei 230032, China; Department of Medical Laboratory Science, Bengbu Medical College, 2600 Donghai Ave, Longzihu, Bengbu 233030, Anhui, China; Department of Neurology, Northwestern University, Ward Building 10-233, 303 East Chicago Avenue, Chicago, IL 60611-3008, USA. Electronic address:

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http://dx.doi.org/10.1016/j.bone.2017.06.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5801258PMC
April 2018

The Hepatoprotection by Oleanolic Acid Preconditioning: Focusing on PPAR Activation.

PPAR Res 2018 2;2018:3180396. Epub 2018 Apr 2.

Department of Gastroenterology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai 200072, China.

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http://dx.doi.org/10.1155/2018/3180396DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5901823PMC
April 2018

Extract Attenuates Development of Dextran Sulfate Sodium Induced Colitis in Mice through Activation of PPAR.

PPAR Res 2018 1;2018:6079101. Epub 2018 Feb 1.

Department of Gastroenterology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai 200072, China.

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http://dx.doi.org/10.1155/2018/6079101DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5816873PMC
February 2018

Apatinib-treated advanced medullary thyroid carcinoma: a case report.

Onco Targets Ther 2018 19;11:459-463. Epub 2018 Jan 19.

Key Laboratory of Nuclear Medicine, Ministry of Health, Jiangsu Key Laboratory of Molecular Nuclear Medicine, Jiangsu Institute of Nuclear Medicine, Wuxi, China.

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http://dx.doi.org/10.2147/OTT.S142598DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5783142PMC
January 2018

By inhibiting PFKFB3, aspirin overcomes sorafenib resistance in hepatocellular carcinoma.

Int J Cancer 2017 12 14;141(12):2571-2584. Epub 2017 Sep 14.

Department of Gastroenterology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, China.

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http://doi.wiley.com/10.1002/ijc.31022
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http://dx.doi.org/10.1002/ijc.31022DOI Listing
December 2017

Hepatoprotective effect of quercetin via TRAF6/JNK pathway in acute hepatitis.

Biomed Pharmacother 2017 Dec 24;96:1137-1146. Epub 2017 Nov 24.

Department of Gastroenterology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai 200072, China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S07533322173486
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http://dx.doi.org/10.1016/j.biopha.2017.11.109DOI Listing
December 2017

Cytoplasmic rods and rings in mycophenolic acid treatment.

Liver Int 2017 11 10;37(11):1742-1743. Epub 2017 Aug 10.

Department of Gastroenterology and Hepatology, Erasmus MC-University Medical Center, Rotterdam, the Netherlands.

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http://dx.doi.org/10.1111/liv.13530DOI Listing
November 2017

Spatio-temporal expression patterns of Wnt signaling pathway during the development of temporomandibular condylar cartilage.

Gene Expr Patterns 2017 11 8;25-26:149-158. Epub 2017 Aug 8.

Department of Stomatology, The First Affiliated Hospital of Dalian Medical University, Dalian 116011, China. Electronic address:

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http://dx.doi.org/10.1016/j.gep.2017.08.001DOI Listing
November 2017

Genistein suppresses aerobic glycolysis and induces hepatocellular carcinoma cell death.

Br J Cancer 2017 Nov 19;117(10):1518-1528. Epub 2017 Sep 19.

Department of Gastroenterology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai 200072, China.

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http://dx.doi.org/10.1038/bjc.2017.323DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680469PMC
November 2017

Clinical value of urinary retinol-binding protein in ascites due to cirrhosis.

Exp Ther Med 2017 Nov 22;14(5):5228-5234. Epub 2017 Sep 22.

Department of Gastroenterology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai 200072, P.R. China.

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http://dx.doi.org/10.3892/etm.2017.5190DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5704310PMC
November 2017

Microenvironmental factors that regulate mesenchymal stem cells: lessons learned from the study of heterotopic ossification.

Histol Histopathol 2017 Oct 22;32(10):977-985. Epub 2017 Mar 22.

School of Basic Medical Sciences, Anhui Medical University, Hefei, China.

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http://dx.doi.org/10.14670/HH-11-890DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5809774PMC
October 2017

Dynamics of Proliferative and Quiescent Stem Cells in Liver Homeostasis and Injury.

Gastroenterology 2017 10 14;153(4):1133-1147. Epub 2017 Jul 14.

Department of Gastroenterology and Hepatology, Erasmus MC-University Medical Center, Rotterdam, The Netherlands. Electronic address:

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http://dx.doi.org/10.1053/j.gastro.2017.07.006DOI Listing
October 2017

The natural product fucoidan ameliorates hepatic ischemia-reperfusion injury in mice.

Biomed Pharmacother 2017 Oct 7;94:687-696. Epub 2017 Aug 7.

Department of Gastroenterology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai 200072, China. Electronic address:

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http://dx.doi.org/10.1016/j.biopha.2017.07.109DOI Listing
October 2017

Cordycepin induces apoptosis of human acute monocytic leukemia cells via downregulation of the ERK/Akt signaling pathway.

Exp Ther Med 2017 Oct 31;14(4):3067-3073. Epub 2017 Jul 31.

Department of Ultrasound, Renji Hospital, Shanghai Jiaotong University Medical School, Shanghai 200127, P.R. China.

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http://dx.doi.org/10.3892/etm.2017.4855DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5585717PMC
October 2017

Antinociceptive Effect of Ghrelin in a Rat Model of Irritable Bowel Syndrome Involves TRPV1/Opioid Systems.

Cell Physiol Biochem 2017 20;43(2):518-530. Epub 2017 Sep 20.

Department of Gastroenterology and Hepatology, Jinshan Hospital of Fudan University, Shanghai, China.

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http://dx.doi.org/10.1159/000480478DOI Listing
October 2017

Quercetin Pretreatment Attenuates Hepatic Ischemia Reperfusion-Induced Apoptosis and Autophagy by Inhibiting ERK/NF-B Pathway.

Gastroenterol Res Pract 2017 16;2017:9724217. Epub 2017 Oct 16.

Department of Gastroenterology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai 200072, China.

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http://dx.doi.org/10.1155/2017/9724217DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5662816PMC
October 2017

Pretreatment with propylene glycol alginate sodium sulfate ameliorated concanavalin A-induced liver injury by regulating the PI3K/Akt pathway in mice.

Life Sci 2017 Sep 31;185:103-113. Epub 2017 Jul 31.

Department of Gastroenterology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai 200072, China. Electronic address:

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http://dx.doi.org/10.1016/j.lfs.2017.07.033DOI Listing
September 2017

Model design for screening effective Antihyperlipidemic drugs using zebrafish system.

Pak J Pharm Sci 2017 Sep;30(5):1697-1707

Department of Cardiology, Shanghai Ninth People's Hospital Affiliated Shanghai Jiaotong University School of Medicine, Shanghai, China.

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September 2017

MicroRNA-9 Inhibits NLRP3 Inflammasome Activation in Human Atherosclerosis Inflammation Cell Models through the JAK1/STAT Signaling Pathway.

Cell Physiol Biochem 2017 27;41(4):1555-1571. Epub 2017 Mar 27.

Department of Cardiology, No. 9 People's Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.

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http://dx.doi.org/10.1159/000470822DOI Listing
June 2017

Galectin‑3 induces the phenotype transformation of human vascular smooth muscle cells via the canonical Wnt signaling.

Mol Med Rep 2017 Jun 3;15(6):3840-3846. Epub 2017 Apr 3.

Department of Cardiology, Shanghai Ninth People's Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai 200011, P.R. China.

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http://dx.doi.org/10.3892/mmr.2017.6429DOI Listing
June 2017

15-Deoxy-Δ-prostaglandin J alleviates hepatic ischemia-reperfusion injury in mice via inducing antioxidant response and inhibiting apoptosis and autophagy.

Acta Pharmacol Sin 2017 May 20;38(5):672-687. Epub 2017 Feb 20.

Department of Gastroenterology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai 200072, China.

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http://www.nature.com/doifinder/10.1038/aps.2016.108
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http://dx.doi.org/10.1038/aps.2016.108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5457695PMC
May 2017

Unphosphorylated ISGF3 drives constitutive expression of interferon-stimulated genes to protect against viral infections.

Sci Signal 2017 Apr 25;10(476). Epub 2017 Apr 25.

Department of Gastroenterology and Hepatology, Postgraduate School Molecular Medicine, Erasmus MC University Medical Center, Rotterdam, Netherlands.

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http://dx.doi.org/10.1126/scisignal.aah4248DOI Listing
April 2017

A meta-analysis of the diagnostic value of detecting K-ras mutation in pancreatic juice as a molecular marker for pancreatic cancer.

Pancreatology 2016 Jul-Aug;16(4):605-14. Epub 2016 May 12.

Department of Gastroenterology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai 200072, China. Electronic address:

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http://dx.doi.org/10.1016/j.pan.2016.04.033DOI Listing
March 2017

[Lipid-lowering effect of seven traditional Chinese medicine monomers in zebrafish system].

Sheng Li Xue Bao 2017 Feb;69(1):55-60

Department of Cardiology, Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai 200011, China.

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February 2017

Shikonin Attenuates Concanavalin A-Induced Acute Liver Injury in Mice via Inhibition of the JNK Pathway.

Mediators Inflamm 2016 16;2016:2748367. Epub 2016 May 16.

Department of Gastroenterology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai 200072, China.

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http://dx.doi.org/10.1155/2016/2748367DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4884842PMC
January 2017

Blocking Wnt Secretion Reduces Growth of Hepatocellular Carcinoma Cell Lines Mostly Independent of β-Catenin Signaling.

Neoplasia 2016 Dec 13;18(12):711-723. Epub 2016 Nov 13.

Department of Gastroenterology and Hepatology, Erasmus MC-University Medical Center, Rotterdam, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.neo.2016.10.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5110474PMC
December 2016

Cerebral Hemodynamics and Cognitive Function in Cirrhotic Patients with Hepatic Encephalopathy.

Gastroenterol Res Pract 2016 21;2016:8485032. Epub 2016 Dec 21.

Department of Gastroenterology, Shanghai Tenth People's Hospital, School of Medicine, Tongji University, Shanghai 200072, China.

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http://dx.doi.org/10.1155/2016/8485032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5209626PMC
December 2016

Protective effect of fucoidan from Fucus vesiculosus on liver fibrosis via the TGF-β1/Smad pathway-mediated inhibition of extracellular matrix and autophagy.

Drug Des Devel Ther 2016 12;10:619-30. Epub 2016 Feb 12.

Department of Gastroenterology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, People's Republic of China.

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http://dx.doi.org/10.2147/DDDT.S98740DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4758785PMC
October 2016

Epigallocatechin-3-gallate attenuates apoptosis and autophagy in concanavalin A-induced hepatitis by inhibiting BNIP3.

Drug Des Devel Ther 2016 15;10:631-47. Epub 2016 Feb 15.

Department of Gastroenterology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, People's Republic of China.

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http://dx.doi.org/10.2147/DDDT.S99420DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4760659PMC
October 2016

Effects of Omega-3 Fatty Acid in Nonalcoholic Fatty Liver Disease: A Meta-Analysis.

Gastroenterol Res Pract 2016 29;2016:1459790. Epub 2016 Aug 29.

Department of Gastroenterology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai 200072, China.

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http://dx.doi.org/10.1155/2016/1459790DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5019889PMC
September 2016

Autophagy regulates resistance of non-small cell lung cancer cells to paclitaxel.

Authors:
Kan Chen Wenjun Shi

Tumour Biol 2016 Aug 8;37(8):10539-44. Epub 2016 Feb 8.

Department of Thoracic Surgery, Shengjing Hospital of China Medical University, 36 Sanhao Street, Shenyang, 110000, China.

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http://dx.doi.org/10.1007/s13277-016-4929-xDOI Listing
August 2016

Heterogeneous recurrence analysis of heartbeat dynamics for the identification of sleep apnea events.

Comput Biol Med 2016 08 14;75:10-8. Epub 2016 May 14.

Harold and Inge Marcus Department of Industrial and Manufacturing Engineering, The Pennsylvania State University, University Park, PA 16802, USA. Electronic address:

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http://dx.doi.org/10.1016/j.compbiomed.2016.05.006DOI Listing
August 2016

Association between chloride-rich versus chloride-restrictive intravenous fluid administration and acute kidney injury in cardiovascular patients in ICU wards.

Exp Ther Med 2016 Aug 6;12(2):987-990. Epub 2016 Jun 6.

Department of Intensive Care Unit, The Second Affiliated Hospital of Xuzhou Medical College, Xuzhou, Jiangsu 221006, P.R. China.

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https://www.spandidos-publications.com/10.3892/etm.2016.3431
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http://dx.doi.org/10.3892/etm.2016.3431DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4950183PMC
August 2016

Systematic review and meta-analysis: bezafibrate in patients with primary biliary cirrhosis.

Drug Des Devel Ther 2015 30;9:5407-19. Epub 2015 Sep 30.

Department of Gastroenterology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, People's Republic of China.

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http://dx.doi.org/10.2147/DDDT.S92041DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4599574PMC
July 2016

Oncogenic role of the Notch pathway in primary liver cancer.

Oncol Lett 2016 Jul 18;12(1):3-10. Epub 2016 May 18.

Department of Gastroenterology, Shanghai Tenth People's Hospital, Tongji University, School of Medicine, Shanghai 200072, P.R. China.

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http://dx.doi.org/10.3892/ol.2016.4609DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4906927PMC
July 2016

Methylation-regulated miR-124-1 suppresses tumorigenesis in hepatocellular carcinoma by targeting CASC3.

Oncotarget 2016 May;7(18):26027-41

Department of Gastroenterology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai 200072, China.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5041962PMC
http://dx.doi.org/10.18632/oncotarget.8266DOI Listing
May 2016

The efficacy and safety of endostar combined with taxane-based regimens for HER-2-negative metastatic breast cancer patients.

Oncotarget 2016 May;7(21):31501-7

Department of Medical Oncology, Fujian Provincial Cancer Hospital, the Teaching Hospital of Fujian Medical University, the Teaching Hospital of Fujian University of Traditional Chinese Medicine, Fuzhou 350014, China.

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http://dx.doi.org/10.18632/oncotarget.8967DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5058773PMC
May 2016

15d-PGJ2 alleviates ConA-induced acute liver injury in mice by up-regulating HO-1 and reducing hepatic cell autophagy.

Biomed Pharmacother 2016 May 26;80:183-192. Epub 2016 Mar 26.

Department of Gastroenterology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai 200072, China. Electronic address:

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http://dx.doi.org/10.1016/j.biopha.2016.03.012DOI Listing
May 2016

Resveratrol inhibits dysfunction of dendritic cells from chronic obstructive pulmonary disease patients through promoting miR-34.

Int J Clin Exp Pathol 2015 1;8(5):5145-52. Epub 2015 May 1.

Department of Critical Care Medicine, The Second Affiliated Hospital of Xuzhou Medical College Jiangsu 221006, PR China.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4503082PMC
April 2016

Sphingosine kinase 1 as an anticancer therapeutic target.

Drug Des Devel Ther 2015 23;9:3239-45. Epub 2015 Jun 23.

Department of Radiotherapy Oncology, First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, People's Republic of China.

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http://dx.doi.org/10.2147/DDDT.S83288DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4484649PMC
March 2016

In vivo validation of an oscillometric method for estimating central aortic pressure.

Int J Cardiol 2015 Nov 1;199:439-41. Epub 2015 Aug 1.

Department of Cardiology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, 639 Zhizaoju Road, Shanghai 200011, China.

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http://dx.doi.org/10.1016/j.ijcard.2015.07.097DOI Listing
November 2015

Galectin-3-induced oxidized low-density lipoprotein promotes the phenotypic transformation of vascular smooth muscle cells.

Mol Med Rep 2015 Oct 13;12(4):4995-5002. Epub 2015 Jul 13.

Department of Cardiology, Shanghai Ninth People's Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai 200011, P.R. China.

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http://dx.doi.org/10.3892/mmr.2015.4075DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4581830PMC
October 2015

Discovery and Evaluation of Clinical Candidate AZD3759, a Potent, Oral Active, Central Nervous System-Penetrant, Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor.

J Med Chem 2015 Oct 9;58(20):8200-15. Epub 2015 Oct 9.

Innovation Center China, Asia & Emerging Markets iMed, AstraZeneca Innovative Medicines and Early Development , 199 Liangjing Road, Zhangjiang Hi-Tech Park, Shanghai 201203, China.

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http://dx.doi.org/10.1021/acs.jmedchem.5b01073DOI Listing
October 2015

Application of chrysophanol in zebrafish to reduce dietary introduced lipid and its possible mechanism.

Int J Clin Exp Med 2015 15;8(7):10558-67. Epub 2015 Jul 15.

Department of Cardiology, Shanghai Ninth People's Hospital Affiliated Shanghai Jiaotong University School of Medicine Shanghai 200011, China.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4565228PMC
September 2015

Association of hydrogen sulfide with alterations of monocyte chemokine receptors, CCR2 and CX3CR1 in patients with coronary artery disease.

Inflamm Res 2015 Aug 30;64(8):627-35. Epub 2015 Jun 30.

Department of Cardiology, Shanghai Ninth People's Hospital, Shanghai JiaoTong University School of Medicine, 639 Zhizaoju Road, Shanghai, 200011, China.

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http://dx.doi.org/10.1007/s00011-015-0844-7DOI Listing
August 2015

The Protective Effect of Resveratrol on Concanavalin-A-Induced Acute Hepatic Injury in Mice.

Gastroenterol Res Pract 2015 24;2015:506390. Epub 2015 May 24.

Department of Gastroenterology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai 200072, China.

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http://dx.doi.org/10.1155/2015/506390DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4458299PMC
June 2015