Dr. Kamal Kishore Joshi, PhD - Roche-Genentech - Postdoctoral Research Fellow

Dr. Kamal Kishore Joshi

PhD

Roche-Genentech

Postdoctoral Research Fellow

Dr. Kamal Kishore Joshi, PhD - Roche-Genentech - Postdoctoral Research Fellow

Dr. Kamal Kishore Joshi

PhD

Introduction

Dr. Kamal Joshi is a postdoctoral research fellow in the Department of Antibody Engineering at Roche/Genentech, US. He received his Ph.D. degree in Molecular and Cellular Biology from University of Massachusetts Amherst, US. During his doctoral work, he defined an adaptor hierarchy, which controls destruction of cell cycle regulators. After completing his Masters degree from IIT Madras, he also worked at Biocon Ltd. India where he focused on developing ways to isolate in large amount the hormonal protein insulin and its derivatives for diabetic’s patients. Dr. Joshi has published papers in many journals including the journal Cell. He also received many awards including a Dissertation Research Grant award from the graduate school of UMass Amherst for conducting his doctoral research.

Primary Affiliation: Roche-Genentech

Research Interests:

Education

May 2017
University of Massachusetts Amherst
PhD

Experience

Nov 2017
Graduate School Dissertation Research Grant
RA

Publications

7Publications

58Reads

17Profile Views

66PubMed Central Citations

Elucidating heavy/light chain pairing preferences to facilitate the assembly of bispecific IgG in single cells.

MAbs 2019 10 26;11(7):1254-1265. Epub 2019 Jul 26.

Department of Antibody Engineering, Genentech, Inc ., South San Francisco , CA , USA.

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http://dx.doi.org/10.1080/19420862.2019.1640549DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6748609PMC
October 2019
1 Read
4.558 Impact Factor

Polar Localization Hub Protein PopZ Restrains Adaptor-Dependent ClpXP Proteolysis in Caulobacter crescentus.

J Bacteriol 2018 10 24;200(20). Epub 2018 Sep 24.

Department of Biochemistry and Molecular Biology, Molecular and Cellular Biology Graduate Program, University of Massachusetts Amherst, Amherst, Massachussetts, USA

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http://dx.doi.org/10.1128/JB.00221-18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6153658PMC
October 2018
1 Read
2.810 Impact Factor

Cargo engagement protects protease adaptors from degradation in a substrate-specific manner.

J Biol Chem 2017 06 15;292(26):10973-10982. Epub 2017 May 15.

From the Department of Biochemistry and Molecular Biology and

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http://dx.doi.org/10.1074/jbc.M117.786392DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5491781PMC
June 2017
12 Reads
4.573 Impact Factor

Regulated Proteolysis in Bacteria: Caulobacter.

Annu Rev Genet 2016 Nov 13;50:423-445. Epub 2016 Oct 13.

Department of Biochemistry and Molecular Biology, University of Massachusetts, Amherst, Massachusetts 01003; email:

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http://dx.doi.org/10.1146/annurev-genet-120215-035235DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5510660PMC
November 2016
3 Reads
10 Citations
15.724 Impact Factor

An Adaptor Hierarchy Regulates Proteolysis during a Bacterial Cell Cycle.

Cell 2015 Oct;163(2):419-31

Department of Biochemistry and Molecular Biology, Molecular and Cellular Biology Graduate Program, University of Massachusetts Amherst, Amherst, MA 01003, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2015.09.030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4600535PMC
October 2015
7 Reads
18 Citations
32.242 Impact Factor

Cell cycle-dependent adaptor complex for ClpXP-mediated proteolysis directly integrates phosphorylation and second messenger signals.

Proc Natl Acad Sci U S A 2014 Sep 2;111(39):14229-34. Epub 2014 Sep 2.

Department of Plant and Microbial Biology, University of California, Berkeley, CA 94720; and

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http://dx.doi.org/10.1073/pnas.1407862111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4191750PMC
September 2014
20 Reads
18 Citations
9.810 Impact Factor

Regulated proteolysis of a transcription factor complex is critical to cell cycle progression in Caulobacter crescentus.

Mol Microbiol 2013 Mar 25;87(6):1277-89. Epub 2013 Feb 25.

Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.

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http://dx.doi.org/10.1111/mmi.12166DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3596498PMC
March 2013
14 Reads
20 Citations
4.420 Impact Factor

Top co-authors

Peter Chien
Peter Chien

Massachusetts Institute of Technology

6
Aron Kamajaya
Aron Kamajaya

California Institute of Technology

1
Katherine Trinh
Katherine Trinh

University of California

1
Justin J Zik
Justin J Zik

University of California

1
Kathleen R Ryan
Kathleen R Ryan

University of California

1
Kasia G Gora
Kasia G Gora

Massachusetts Institute of Technology

1
Michael T Laub
Michael T Laub

Massachusetts Institute of Technology

1
Barrett S Perchuk
Barrett S Perchuk

Massachusetts Institute of Technology

1
Matthew Wohlever
Matthew Wohlever

The University of Chicago

1