Kaichun Wu

Kaichun Wu

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Kaichun Wu

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MicroRNA-31 Reduces Inflammatory Signaling and Promotes Regeneration in Colon Epithelium, and Delivery of Mimics in Microspheres Reduces Colitis in Mice.

Gastroenterology 2019 06 16;156(8):2281-2296.e6. Epub 2019 Feb 16.

State Key Laboratories for Agrobiotechnology and Beijing Advanced Innovation Center for Food Nutrition and Human Health and, College of Biological Sciences, China Agricultural University, Beijing, China. Electronic address:

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http://dx.doi.org/10.1053/j.gastro.2019.02.023DOI Listing
June 2019

Sex determining region Y-box 12 (SOX12) promotes gastric cancer metastasis by upregulating MMP7 and IGF1.

Cancer Lett 2019 Jun 25;452:103-118. Epub 2019 Mar 25.

State Key Laboratory of Cancer Biology, National Clinical Research Center for Digestive Diseases and Xijing Hospital of Digestive Diseases, Fourth Military Medical University, Xi'an, 710032, Shaanxi Province, China; Department of Gastroenterology, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, Hubei Province, China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S03043835193019
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http://dx.doi.org/10.1016/j.canlet.2019.03.035DOI Listing
June 2019

Correction: O-GlcNAcylation promotes colorectal cancer metastasis via the miR-101-O-GlcNAc/EZH2 regulatory feedback circuit.

Oncogene 2019 Jun 3. Epub 2019 Jun 3.

State Key Laboratory of Cancer Biology, National Clinical Research Center for Digestive Diseases and Xijing Hospital of Digestive Diseases, Fourth Military Medical University, Xi'an, China.

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http://dx.doi.org/10.1038/s41388-019-0834-2DOI Listing
June 2019

Author Correction: Enah overexpression is correlated with poor survival and aggressive phenotype in gastric cancer.

Cell Death Dis 2019 May 7;10(5):366. Epub 2019 May 7.

State Key Laboratory of Cancer Biology and Xijing Hospital of Digestive Diseases, the Air Force Military Medical University, 127 Changle Western Road, Xi'an, Shaanxi Province, 710032, China.

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http://dx.doi.org/10.1038/s41419-019-1573-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6504849PMC
May 2019

Early TIPS with covered stents versus standard treatment for acute variceal bleeding in patients with advanced cirrhosis: a randomised controlled trial.

Lancet Gastroenterol Hepatol 2019 May 29. Epub 2019 May 29.

Department of Liver Diseases and Digestive Interventional Radiology, National Clinical Research Centre for Digestive Diseases and Xijing Hospital of Digestive Diseases, Fourth Military Medical University, Xi'an, China. Electronic address:

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http://dx.doi.org/10.1016/S2468-1253(19)30090-1DOI Listing
May 2019

Defining UHRF1 Domains that Support Maintenance of Human Colon Cancer DNA Methylation and Oncogenic Properties.

Cancer Cell 2019 Apr 4;35(4):633-648.e7. Epub 2019 Apr 4.

The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, The Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA; Center for Epigenetics, Van Andel Research Institute, Grand Rapids, MI 49503, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2019.03.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6521721PMC
April 2019

QingBai decoction regulates intestinal permeability of dextran sulphate sodium-induced colitis through the modulation of notch and NF-κB signalling.

Cell Prolif 2019 Mar 18;52(2):e12547. Epub 2019 Jan 18.

State Key Laboratory of Cancer Biology and Institute of Digestive Diseases, Xijing Hospital, The Fourth Military Medical University, Xi'an, China.

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http://dx.doi.org/10.1111/cpr.12547DOI Listing
March 2019

Comparison of the efficiency of different enemas on patients with distal ulcerative colitis.

Cell Prolif 2019 Mar 18;52(2):e12559. Epub 2019 Jan 18.

State Key Laboratory of Cancer Biology, National Clinical Research Center for Digestive Diseases and Xijing Hospital of Digestive Diseases, Air Force Military Medical University, Xi'an, China.

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http://doi.wiley.com/10.1111/cpr.12559
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http://dx.doi.org/10.1111/cpr.12559DOI Listing
March 2019

SOX12 promotes colorectal cancer cell proliferation and metastasis by regulating asparagine synthesis.

Cell Death Dis 2019 Mar 11;10(3):239. Epub 2019 Mar 11.

State Key Laboratory of Cancer Biology, National Clinical Research Center for Digestive Diseases and Xijing Hospital of Digestive Diseases, Fourth Military Medical University, Xi'an, 710032, Shaanxi Province, China.

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http://www.nature.com/articles/s41419-019-1481-9
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http://dx.doi.org/10.1038/s41419-019-1481-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6412063PMC
March 2019

O-GlcNAcylation promotes colorectal cancer metastasis via the miR-101-O-GlcNAc/EZH2 regulatory feedback circuit.

Oncogene 2019 01 9;38(3):301-316. Epub 2018 Aug 9.

State key Laboratory of Cancer Biology, National Clinical Research Center for Digestive Diseases and Xijing Hospital of Digestive Diseases, Fourth Military Medical University, Xi'an, China.

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http://dx.doi.org/10.1038/s41388-018-0435-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6336687PMC
January 2019

MicroRNA-92a-1-5p increases CDX2 by targeting FOXD1 in bile acids-induced gastric intestinal metaplasia.

Gut 2019 Jan 11. Epub 2019 Jan 11.

State Key Laboratory of Cancer Biology and Xijing Hospital of Digestive Diseases, Xijing Hospital, The Fourth Military Medical University, Xi'an, China.

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http://gut.bmj.com/lookup/doi/10.1136/gutjnl-2017-315318
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http://dx.doi.org/10.1136/gutjnl-2017-315318DOI Listing
January 2019

Covered TIPS versus endoscopic band ligation plus propranolol for the prevention of variceal rebleeding in cirrhotic patients with portal vein thrombosis: a randomised controlled trial.

Gut 2018 12 28;67(12):2156-2168. Epub 2017 Sep 28.

Department of Liver Diseases and Digestive Interventional Radiology, National Clinical Research Center for Digestive Diseases and Xijing Hospital of Digestive Diseases, Fourth Military Medical University, Xi'an, China.

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http://dx.doi.org/10.1136/gutjnl-2017-314634DOI Listing
December 2018

PD-L1 expression and the prognostic significance in gastric cancer: a retrospective comparison of three PD-L1 antibody clones (SP142, 28-8 and E1L3N).

Diagn Pathol 2018 Nov 21;13(1):91. Epub 2018 Nov 21.

State Key Laboratory of Cancer Biology and Institute of Digestive Diseases, Xijing Hospital, The Fourth Military Medical University, Xi'an, China.

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http://dx.doi.org/10.1186/s13000-018-0766-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6249875PMC
November 2018

Forkhead box C1 promotes colorectal cancer metastasis through transactivating ITGA7 and FGFR4 expression.

Oncogene 2018 10 8;37(41):5477-5491. Epub 2018 Jun 8.

State Key Laboratory of Cancer Biology, National Clinical Research Center for Digestive Diseases and Xijing Hospital of Digestive Diseases, Fourth Military Medical University, Xi'an, China.

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http://dx.doi.org/10.1038/s41388-018-0355-4DOI Listing
October 2018

Efficacy and Tolerability of First-Line Cetuximab Plus Leucovorin, Fluorouracil, and Oxaliplatin (FOLFOX-4) Versus FOLFOX-4 in Patients With Wild-Type Metastatic Colorectal Cancer: The Open-Label, Randomized, Phase III TAILOR Trial.

J Clin Oncol 2018 Oct 10;36(30):3031-3039. Epub 2018 Sep 10.

Shukui Qin, Bayi Hospital, Nanjing University of Chinese Medicine, Nanjing; Jin Li, Fudan University Cancer Hospital and Tongji University East Hospital; Liwei Wang, Shanghai First People's Hospital; Jun Zhang, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine; Tianshu Liu, Affiliated Zhongshan Hospital of Fudan University, Shanghai; Jianming Xu, 307 Hospital of the Chinese People's Liberation Army; Guanghai Dai, Chinese People's Liberation Army General Hospital; Junyuan Wang and Jiongjie Chen, Merck Serono, Beijing; Ying Cheng, Jilin Cancer Hospital; Wei Li, First Affiliated Hospital of Jilin University, Jilin; Yuxian Bai, Affiliated Hospital of Harbin Medical University, Harbin; Nong Xu, First Affiliated Hospital of College of Medicine, Zhejiang University, Hangzhou; Li-zhu Lin, First Affiliated Hospital of Guangzhou University of Traditional Chinese Medicine, Guangzhou; Qiong Wu, First Affiliated Hospital of Bengbu Medical College, Bengbu; Yunfeng Li, Yunnan Province Cancer Hospital, Kunming; Jianwei Yang, Fujian Province Cancer Hospital; Xuenong Ouyang, Fuzhou General Hospital, Fuzhou; Hongming Pan, Sir Run Run Shaw Hospital Affiliated With School of Medicine, Zhejiang University, Zhejiang; Wensheng Qiu, Affiliated Hospital of Qingdao University, Qingdao; Kaichun Wu, Xijing Hospital, Fourth Military Medical University, Shaanxi; Jianping Xiong, First Affiliated Hospital of Nanchang University, Nanchang; Houjie Liang, Southwest Cancer Center, Southwest Hospital, Third Military Medical University, Chongqing; Chunhong Hu, Second Xiangya Hospital of Central South University, Changsha; Min Tao, First Affiliated Hospital of Suzhou University, Suzhou; Qiang Yao, Tianjin People's Hospital, Tianjin, People's Republic of China; and S. Peter Eggleton, Merck KGaA, Darmstadt, Germany.

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http://dx.doi.org/10.1200/JCO.2018.78.3183DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6324088PMC
October 2018

Enah overexpression is correlated with poor survival and aggressive phenotype in gastric cancer.

Cell Death Dis 2018 Sep 24;9(10):998. Epub 2018 Sep 24.

State Key Laboratory of Cancer Biology and Xijing Hospital of Digestive Diseases, the Air Force Military Medical University, 127 Changle Western Road, Xi'an, Shaanxi Province, 710032, China.

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http://dx.doi.org/10.1038/s41419-018-1031-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155292PMC
September 2018

PTEN lipid phosphatase inactivation links the hippo and PI3K/Akt pathways to induce gastric tumorigenesis.

J Exp Clin Cancer Res 2018 Aug 22;37(1):198. Epub 2018 Aug 22.

Department of Gastroenterology, The First Affiliated Hospital of Nanchang University, Nanchang, 330006, Jiangxi, China.

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http://dx.doi.org/10.1186/s13046-018-0795-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6104022PMC
August 2018

MicroRNA-26a is a key regulon that inhibits progression and metastasis of c-Myc/EZH2 double high advanced hepatocellular carcinoma.

Cancer Lett 2018 07 11;426:98-108. Epub 2018 Apr 11.

State Key Laboratory of Cancer Biology, Department of Biochemistry and Molecular Biology, Fourth Military Medical University, Xi'an, Shaanxi, 710032, China. Electronic address:

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http://dx.doi.org/10.1016/j.canlet.2018.04.005DOI Listing
July 2018

CD177 neutrophils as functionally activated neutrophils negatively regulate IBD.

Gut 2018 06 3;67(6):1052-1063. Epub 2017 May 3.

Department of Gastroenterology, The Shanghai Tenth People's Hospital, Tongji University, Shanghai, China.

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http://dx.doi.org/10.1136/gutjnl-2016-313535DOI Listing
June 2018

Microbiota transplantation: concept, methodology and strategy for its modernization.

Protein Cell 2018 05 24;9(5):462-473. Epub 2018 Apr 24.

State Key Laboratory of Cancer Biology & Xijing Hospital of Digestive Diseases, Fourth Military Medical University, Xi'an, 710032, China.

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http://dx.doi.org/10.1007/s13238-018-0541-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5960466PMC
May 2018

Novel peptide GX1 inhibits angiogenesis by specifically binding to transglutaminase-2 in the tumorous endothelial cells of gastric cancer.

Cell Death Dis 2018 May 21;9(6):579. Epub 2018 May 21.

State key Laboratory of Cancer Biology, National Clinical Research Center for Digestive Diseases and Xijing Hospital of Digestive Diseases, Fourth Military Medical University, Xi'an, 710032, Shaanxi Province, People's Republic of China.

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http://dx.doi.org/10.1038/s41419-018-0594-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5962530PMC
May 2018

Gasdermin D plays a key role as a pyroptosis executor of non-alcoholic steatohepatitis in humans and mice.

J Hepatol 2018 04 20;68(4):773-782. Epub 2017 Dec 20.

State Key Laboratory of Cancer Biology, National Clinical Research Center for Digestive Diseases and Xijing Hospital of Digestive Diseases, Fourth Military Medical University, Xi'an, Shaanxi, MI 710032, China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01688278173249
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http://dx.doi.org/10.1016/j.jhep.2017.11.040DOI Listing
April 2018

Investigation of the influence of sampling schemes on quantitative dynamic fluorescence imaging.

Biomed Opt Express 2018 Apr 26;9(4):1859-1870. Epub 2018 Mar 26.

Engineering Research Center of Molecular and Neuro Imaging of Ministry of Education & School of Life Science and Technology, Xidian University, Xi'an, Shaanxi 710071, China.

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http://dx.doi.org/10.1364/BOE.9.001859DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5905930PMC
April 2018

NDRG2 facilitates colorectal cancer differentiation through the regulation of Skp2-p21/p27 axis.

Oncogene 2018 03 18;37(13):1759-1774. Epub 2018 Jan 18.

The State Key Laboratory of Cancer Biology, Department of Biochemistry and Molecular Biology, The Fourth Military Medical University, Xi'an, China.

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http://dx.doi.org/10.1038/s41388-017-0118-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5874257PMC
March 2018

Small intestinal diverticulum with bleeding: Case report and literature review.

Medicine (Baltimore) 2018 Mar;97(9):e9871

Emergency Room of Digestive Diseases, National Clinical Research Center for Digestive Diseases and Xijing Hospital of Digestive Diseases, Fourth Military Medical University, Xi'an.

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http://dx.doi.org/10.1097/MD.0000000000009871DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5851745PMC
March 2018

miR-148b-3p inhibits gastric cancer metastasis by inhibiting the Dock6/Rac1/Cdc42 axis.

J Exp Clin Cancer Res 2018 Mar 27;37(1):71. Epub 2018 Mar 27.

State Key Laboratory of Cancer Biology & National Clinical Research Center for Digestive Diseases and Xijing Hospital of Digestive Diseases, Fourth Military Medical University, 127 West Changle Road, Xi'an, Shaanxi, 710032, China.

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https://jeccr.biomedcentral.com/articles/10.1186/s13046-018-
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http://dx.doi.org/10.1186/s13046-018-0729-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5872400PMC
March 2018

The Pathological Features of Colorectal Cancer Determine the Detection Performance on Blood ctDNA.

Technol Cancer Res Treat 2018 01;17:1533033818791794

1 National Clinical Research Center for Digestive Disease and Xijing Hospital of Digestive Diseases, Fourth Military Medical University, Xi'an, Shaanxi, China.

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http://dx.doi.org/10.1177/1533033818791794DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6144579PMC
January 2018

BMI1 and MEL18 Promote Colitis-Associated Cancer in Mice via REG3B and STAT3.

Gastroenterology 2017 12 3;153(6):1607-1620. Epub 2017 Aug 3.

National Institute of Biological Sciences, Beijing, China; Shanghai 10th People's Hospital, School of Life Science and Technology, Tongji University, Shanghai, China. Electronic address:

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http://dx.doi.org/10.1053/j.gastro.2017.07.044DOI Listing
December 2017

FOXK1 plays an oncogenic role in the development of esophageal cancer.

Biochem Biophys Res Commun 2017 12 16;494(1-2):88-94. Epub 2017 Oct 16.

State Key Laboratory of Cancer Biology and Xijing Hospital of Digestive Diseases, The Fourth Military Medical University, 127 Changle Western Road, Xi'an, Shaanxi Province, 710032, China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S0006291X173205
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http://dx.doi.org/10.1016/j.bbrc.2017.10.080DOI Listing
December 2017

Efficacy and safety of endoscopic submucosal tunnel dissection for superficial esophageal squamous cell carcinoma: a propensity score matching analysis.

Gastrointest Endosc 2017 Nov 9;86(5):831-838. Epub 2017 Mar 9.

Xijing Hospital of Digestive Diseases, Fourth Military Medical University, Xi'an, China.

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http://dx.doi.org/10.1016/j.gie.2017.03.001DOI Listing
November 2017

NDRG2 acts as a PERK co-factor to facilitate PERK branch and ERS-induced cell death.

FEBS Lett 2017 11 15;591(21):3670-3681. Epub 2017 Oct 15.

State Key Laboratory of Cancer Biology, Department of Biochemistry and Molecular Biology, The Fourth Military Medical University, Xi'an, China.

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http://dx.doi.org/10.1002/1873-3468.12861DOI Listing
November 2017

Cost-effectiveness analysis of fecal microbiota transplantation for inflammatory bowel disease.

Oncotarget 2017 Oct 4;8(51):88894-88903. Epub 2017 Oct 4.

Medical Center for Digestive Diseases, The Second Affiliated Hospital of Nanjing Medical University, Nanjing 210011, China.

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http://www.oncotarget.com/fulltext/21491
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http://dx.doi.org/10.18632/oncotarget.21491DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5687655PMC
October 2017

Eight millimetre covered TIPS does not compromise shunt function but reduces hepatic encephalopathy in preventing variceal rebleeding.

J Hepatol 2017 09 12;67(3):508-516. Epub 2017 May 12.

Department of Liver Disease and Digestive Interventional Radiology, National Clinical Research Center for Digestive Diseases and Xijing Hospital of Digestive Diseases, Fourth Military Medical University, Xi'an 710032, China. Electronic address:

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http://dx.doi.org/10.1016/j.jhep.2017.05.006DOI Listing
September 2017

Combined Detection of NUDT15 Variants Could Highly Predict Thiopurine-induced Leukopenia in Chinese Patients with Inflammatory Bowel Disease: A Multicenter Analysis.

Inflamm Bowel Dis 2017 09;23(9):1592-1599

*Department of Gastroenterology, Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases, the Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, P.R. China; †Institute of Clinical Pharmacology, School of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou, China; ‡Department of Gastroenterology, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China; §Department of Gastroenterology, Peking Union Medical College Hospital, Beijing, China; ‖Department of Gastroenterology, Xijing Hospital, the Fourth Military Medical University, Xi'an, China; and ¶Department of Colorectal Surgery, the Sixth Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China.

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https://academic.oup.com/ibdjournal/article/23/9/1592-1599/4
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http://dx.doi.org/10.1097/MIB.0000000000001148DOI Listing
September 2017

Differentiated tumor immune microenvironment of Epstein-Barr virus-associated and negative gastric cancer: implication in prognosis and immunotherapy.

Oncotarget 2017 Sep 16;8(40):67094-67103. Epub 2017 May 16.

Fourth Military Medical University, State Key Laboratory of Cancer Biology & Institute of Digestive Diseases, Xijing Hospital, Xi'an, Shaanxi, China.

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http://dx.doi.org/10.18632/oncotarget.17945DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5620158PMC
September 2017

Loss of Barx1 promotes hepatocellular carcinoma metastasis through up-regulating MGAT5 and MMP9 expression and indicates poor prognosis.

Oncotarget 2017 Sep 30;8(42):71867-71880. Epub 2017 May 30.

State Key Laboratory of Cancer Biology, National Clinical Research Center for Digestive Diseases and Xijing Hospital of Digestive Diseases, Fourth Military Medical University, Xi'an 710032, Shaanxi Province, People's Republic of China.

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http://dx.doi.org/10.18632/oncotarget.18288DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5641096PMC
September 2017

Increased expression of calponin 2 is a positive prognostic factor in pancreatic ductal adenocarcinoma.

Oncotarget 2017 Aug 9;8(34):56428-56442. Epub 2017 May 9.

State Key Laboratory of Cancer Biology and Institute of Digestive Diseases, Xijing Hospital, The Fourth Military Medical University, Xi'an, China.

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http://dx.doi.org/10.18632/oncotarget.17701DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5593573PMC
August 2017

HMGA2-FOXL2 Axis Regulates Metastases and Epithelial-to-Mesenchymal Transition of Chemoresistant Gastric Cancer.

Clin Cancer Res 2017 07 24;23(13):3461-3473. Epub 2017 Jan 24.

State Key Laboratory of Cancer Biology and Xijing Hospital of Digestive Diseases, Xijing Hospital, Fourth Military Medical University, Xi'an, China.

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http://dx.doi.org/10.1158/1078-0432.CCR-16-2180DOI Listing
July 2017

A global burden of gastric cancer: the major impact of China.

Expert Rev Gastroenterol Hepatol 2017 Jul 10;11(7):651-661. Epub 2017 Apr 10.

a State Key Laboratory of Cancer Biology and Xijing Hospital of Digestive Diseases , Fourth Military Medical University , Xi'an , China.

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http://dx.doi.org/10.1080/17474124.2017.1312342DOI Listing
July 2017

Multiple fresh fecal microbiota transplants induces and maintains clinical remission in Crohn's disease complicated with inflammatory mass.

Sci Rep 2017 07 6;7(1):4753. Epub 2017 Jul 6.

Medical Center for Digestive Diseases, the Second Affiliated Hospital of Nanjing Medical University, 121 Jiang Jia Yuan, Nanjing, 210011, China.

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http://dx.doi.org/10.1038/s41598-017-04984-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5500501PMC
July 2017

Identification of miRNA-7 by genome-wide analysis as a critical sensitizer for TRAIL-induced apoptosis in glioblastoma cells.

Nucleic Acids Res 2017 Jun;45(10):5930-5944

The State Key Laboratory of Cancer Biology, Department of Biochemistry and Molecular Biology, The Fourth Military Medical University, Xi'an, Shaanxi 710032, P.R. China.

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http://dx.doi.org/10.1093/nar/gkx317DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5449600PMC
June 2017

CHD4 Has Oncogenic Functions in Initiating and Maintaining Epigenetic Suppression of Multiple Tumor Suppressor Genes.

Cancer Cell 2017 05;31(5):653-668.e7

Department of Oncology, Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, The Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2017.04.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5587180PMC
May 2017

Chronic inflammation confers to the metabolic reprogramming associated with tumorigenesis of colorectal cancer.

Cancer Biol Ther 2017 04 25;18(4):237-244. Epub 2017 Feb 25.

a The State Key Laboratory of Cancer Biology, Department of Biochemistry and Molecular Biology , The Fourth Military Medical University , Xian , China.

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http://dx.doi.org/10.1080/15384047.2017.1294292DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5450783PMC
April 2017

Gastric Cancer Cell Proliferation and Survival Is Enabled by a Cyclophilin B/STAT3/miR-520d-5p Signaling Feedback Loop.

Cancer Res 2017 03 23;77(5):1227-1240. Epub 2016 Dec 23.

State Key Laboratory of Cancer Biology & Xijing Hospital of Digestive Diseases, Xijing Hospital, The Fourth Military Medical University, Xi'an, China.

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http://dx.doi.org/10.1158/0008-5472.CAN-16-0357DOI Listing
March 2017

NDRG2 overexpression suppresses hepatoma cells survival during metabolic stress through disturbing the activation of fatty acid oxidation.

Biochem Biophys Res Commun 2017 02 7;483(2):860-866. Epub 2017 Jan 7.

The State Key Laboratory of Cancer Biology, Department of Biochemistry and Molecular Biology, The Fourth Military Medical University, Xi'an, Shaanxi Province, China. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2017.01.018DOI Listing
February 2017

Chaperone-mediated autophagy regulates proliferation by targeting RND3 in gastric cancer.

Autophagy 2016 ;12(3):515-28

a State Key Laboratory of Cancer Biology & Xijing Hospital of Digestive Diseases , Fourth Military Medical University , Xi'an , China.

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http://dx.doi.org/10.1080/15548627.2015.1136770DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4836009PMC
December 2016

Prevalence of colorectal cancer in patients with ulcerative colitis: A retrospective, monocenter study in China.

J Cancer Res Ther 2015 Oct-Dec;11(4):899-903

State Key Laboratory of Cancer Biology and Xijing Hospital of Digestive Diseases, Xijing Hospital, Fourth Military Medical University, Xi'an 710032, Shaanxi Province, P. R. China.

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http://dx.doi.org/10.4103/0973-1482.143345DOI Listing
December 2016

Risk Genes of Inflammatory Bowel Disease in Asia: What Are the Most Important Pathways Affected?

Dig Dis 2016 16;34(1-2):5-11. Epub 2016 Mar 16.

Department of Gastroenterology, Xijing Hospital, The Fourth Military Medical University, Xi'an, China.

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http://dx.doi.org/10.1159/000442917DOI Listing
December 2016

New Generation of Gold Nanoshell-Coated Esophageal Stent: Preparation and Biomedical Applications.

ACS Appl Mater Interfaces 2016 Oct 5;8(41):27523-27529. Epub 2016 Oct 5.

Laboratory of Molecular Imaging and Nanomedicine (LOMIN), National Institute of Biomedical Imaging and Bioengineering (NIBIB), National Institutes of Health , Bethesda, Maryland 20892, United States.

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http://dx.doi.org/10.1021/acsami.6b09104DOI Listing
October 2016

Investigation of injection dose and camera integration time on quantifying pharmacokinetics of a Cy5.5-GX1 probe with dynamic fluorescence imaging in vivo.

J Biomed Opt 2016 08;21(8):86001

Xidian University, Engineering Research Center of Molecular and Neuro Imaging of Ministry of Education and School of Life Science and Technology, 266 Xinglong Section of Xifeng Road, Xi'an 710071, China.

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http://dx.doi.org/10.1117/1.JBO.21.8.086001DOI Listing
August 2016

Intraperitoneal injection (IP), Intravenous injection (IV) or anal injection (AI)? Best way for mesenchymal stem cells transplantation for colitis.

Sci Rep 2016 08 4;6:30696. Epub 2016 Aug 4.

State Key Laboratory of Cancer Biology, Department of Digestive Diseases, Xijing Hospital, Fourth Military Medical University, Xi'an, 710032, China.

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http://dx.doi.org/10.1038/srep30696DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4973258PMC
August 2016

Step-up fecal microbiota transplantation (FMT) strategy.

Gut Microbes 2016 07 3;7(4):323-328. Epub 2016 Mar 3.

a Medical Center for Digestive Diseases , the Second Affiliated Hospital of Nanjing Medical University , Nanjing , China.

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http://dx.doi.org/10.1080/19490976.2016.1151608DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4988439PMC
July 2016

Colonic transendoscopic enteral tubing: A novel way of transplanting fecal microbiota.

Endosc Int Open 2016 Jun 28;4(6):E610-3. Epub 2016 Apr 28.

Medical Center for Digestive Diseases, the Second Affiliated Hospital of Nanjing Medical University, Nanjing 210011, Jiangsu Province, China.; Key Lab of Holistic Integrative Enterology, Nanjing Medical University, 121 Jiangjiayuan, Nanjing 210011, Jiangsu Province, China.

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http://dx.doi.org/10.1055/s-0042-105205DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4993903PMC
June 2016

Multidrug-Resistance Related Long Non-Coding RNA Expression Profile Analysis of Gastric Cancer.

PLoS One 2015 20;10(8):e0135461. Epub 2015 Aug 20.

State Key Laboratory of Cancer Biology and Xijing Hospital of Digestive Diseases, Fourth Military Medical University, 15 Changlexi Road, Xi'an, Shaanxi, China.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0135461PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4546299PMC
May 2016

In vivo quantifying molecular specificity of Cy5.5-labeled cyclic 9-mer peptide probe with dynamic fluorescence imaging.

Biomed Opt Express 2016 Apr 4;7(4):1149-59. Epub 2016 Mar 4.

Engineering Research Center of Molecular and Neuro Imaging of Ministry of Education & School of Life Science and Technology, Xidian University, Xi'an, Shaanxi 710071, China;

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http://dx.doi.org/10.1364/BOE.7.001149DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4929628PMC
April 2016

Delivery of Instructions via Mobile Social Media App Increases Quality of Bowel Preparation.

Clin Gastroenterol Hepatol 2016 Mar 20;14(3):429-435.e3. Epub 2015 Oct 20.

Xijing Hospital of Digestive Diseases, Fourth Military Medical University, Xian, China. Electronic address:

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http://dx.doi.org/10.1016/j.cgh.2015.09.038DOI Listing
March 2016

Comparison of O-Type HybridKnife to Conventional Knife in Endoscopic Submucosal Dissection for Gastric Mucosal Lesions.

Medicine (Baltimore) 2016 Mar;95(13):e3148

From the Xijing Hospital of Digestive Diseases, Fourth Military Medical University (RH, GR, YP, LZ, ZL, XG, KW), and The First Affiliated Hospital of Xi'an Medical University, Xi'an, China (HY).

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http://dx.doi.org/10.1097/MD.0000000000003148DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4998536PMC
March 2016

The miR27b-CCNG1-P53-miR-508-5p axis regulates multidrug resistance of gastric cancer.

Oncotarget 2016 Jan;7(1):538-49

State Key Laboratory of Cancer Biology & Xijing Hospital of Digestive Diseases, Xijing Hospital, Fourth Military Medical University, Xi'an 710032, China.

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http://dx.doi.org/10.18632/oncotarget.6374DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4808016PMC
January 2016

Structure-Based Discovery of Novel and Selective 5-Hydroxytryptamine 2B Receptor Antagonists for the Treatment of Irritable Bowel Syndrome.

J Med Chem 2016 Jan 7;59(2):707-20. Epub 2016 Jan 7.

National Institute of Biological Sciences, Beijing, No. 7 Science Park Road, Zhongguancun Life Science Park, Beijing 102206, China.

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http://dx.doi.org/10.1021/acs.jmedchem.5b01631DOI Listing
January 2016

Evaluation of Tc-99 m Labeled Dimeric GX1 Peptides for Imaging of Colorectal Cancer Vasculature.

Mol Imaging Biol 2015 Oct;17(5):661-70

State Key Laboratory of Cancer Biology and Xijing Hospital of Digestive Diseases, Xijing Hospital, Fourth Military Medical University, Xi'an, 710032, China.

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http://link.springer.com/10.1007/s11307-015-0838-4
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http://dx.doi.org/10.1007/s11307-015-0838-4DOI Listing
October 2015

Interleukin-8 Induces Expression of FOXC1 to Promote Transactivation of CXCR1 and CCL2 in Hepatocellular Carcinoma Cell Lines and Formation of Metastases in Mice.

Gastroenterology 2015 Oct 9;149(4):1053-67.e14. Epub 2015 Jun 9.

State Key Laboratory of Cancer Biology and Xijing Hospital of Digestive Diseases, Fourth Military Medical University, Xi'an, Shaanxi Province, People's Republic of China; Department of Gastroenterology, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei Province, People's Republic of China. Electronic address:

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http://dx.doi.org/10.1053/j.gastro.2015.05.058DOI Listing
October 2015

High Expression of GRP78 Promotes Invasion and Metastases in Patients with Esophageal Squamous Cell Carcinoma.

Dig Dis Sci 2015 Sep 15;60(9):2690-9. Epub 2015 May 15.

State Key Laboratory of Cancer Biology, Xijing Hospital of Digestive Diseases, Fourth Military Medical University, 15 Changle Western Road, Xi'an, 710032, Shaanxi Province, China.

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http://dx.doi.org/10.1007/s10620-015-3689-6DOI Listing
September 2015

Step-up fecal microbiota transplantation strategy: a pilot study for steroid-dependent ulcerative colitis.

J Transl Med 2015 Sep 12;13:298. Epub 2015 Sep 12.

Medical Center for Digestive Diseases, The Second Affiliated Hospital of Nanjing Medical University, 121 Jiangjiayuan, 210011, Nanjing, China.

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http://dx.doi.org/10.1186/s12967-015-0646-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4567790PMC
September 2015

Appropriate time for selective biliary cannulation by trainees during ERCP--a randomized trial.

Endoscopy 2015 Aug 6;47(8):688-95. Epub 2015 Mar 6.

Xijing Hospital of Digestive Diseases, Fourth Military Medical University, Xian, China.

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http://dx.doi.org/10.1055/s-0034-1391564DOI Listing
August 2015

Feasibility study of novel endoscopic Cerenkov luminescence imaging system in detecting and quantifying gastrointestinal disease: first human results.

Eur Radiol 2015 Jun 11;25(6):1814-22. Epub 2015 Jan 11.

State Key Laboratory of Cancer Biology, Department of Digestive Diseases, Xijing Hospital, Fourth Military Medical University, Xi'an, 710032, China.

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http://link.springer.com/content/pdf/10.1007/s00330-014-3574
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http://link.springer.com/10.1007/s00330-014-3574-2
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http://dx.doi.org/10.1007/s00330-014-3574-2DOI Listing
June 2015

Sox12, a direct target of FoxQ1, promotes hepatocellular carcinoma metastasis through up-regulating Twist1 and FGFBP1.

Hepatology 2015 Jun 8;61(6):1920-33. Epub 2015 Apr 8.

State Key Laboratory of Cancer Biology and Xijing Hospital of Digestive Diseases, Fourth Military Medical University, Xi'an, People's Republic of China.

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http://dx.doi.org/10.1002/hep.27756DOI Listing
June 2015

SOX2, a predictor of survival in gastric cancer, inhibits cell proliferation and metastasis by regulating PTEN.

Cancer Lett 2015 Mar 24;358(2):210-219. Epub 2014 Dec 24.

State key Laboratory of Cancer Biology and Xijing Hospital of Digestive Diseases, Xijing Hospital, Fourth Military Medical University, Xi'an, Shaanxi 710032, China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S03043835140080
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http://dx.doi.org/10.1016/j.canlet.2014.12.045DOI Listing
March 2015

Activation of PAX3-MET pathways due to miR-206 loss promotes gastric cancer metastasis.

Carcinogenesis 2015 Mar 3;36(3):390-9. Epub 2015 Feb 3.

State Key Laboratory of Cancer Biology, Xijing Hospital of Digestive Diseases, The Fourth Military Medical University, 17 Changle Western Road, Xi'an, Shaanxi Province 710032, People's Republic of China,

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http://dx.doi.org/10.1093/carcin/bgv009DOI Listing
March 2015

Evaluation of 68Ga-labeled MG7 antibody: a targeted probe for PET/CT imaging of gastric cancer.

Sci Rep 2015 Mar 3;5:8626. Epub 2015 Mar 3.

State Key Laboratory of Cancer Biology &Institute of Digestive Diseases, Xijing Hospital, The Fourth Military Medical University, Xi'an, China.

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http://dx.doi.org/10.1038/srep08626DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4346831PMC
March 2015

Ultrasensitive in vivo detection of primary gastric tumor and lymphatic metastasis using upconversion nanoparticles.

ACS Nano 2015 Feb 26;9(2):2120-9. Epub 2015 Jan 26.

Institute of Chemistry, Chinese Academy of Sciences , Bei Yi Jie 2, Zhong Guan Cun, Beijing 100190, China.

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http://dx.doi.org/10.1021/nn507433pDOI Listing
February 2015

Genistein suppresses FLT4 and inhibits human colorectal cancer metastasis.

Oncotarget 2015 Feb;6(5):3225-39

State Key Laboratory of Cancer Biology and Xijing Hospital of Digestive Diseases, Xijing Hospital, Fourth Military Medical University, Xi'an, Shaanxi Province, PR China.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4413649PMC
http://dx.doi.org/10.18632/oncotarget.3064DOI Listing
February 2015

In vivo molecular imaging of gastric cancer in human-murine xenograft models with confocal laser endomicroscopy using a tumor vascular homing peptide.

Cancer Lett 2015 Jan 11;356(2 Pt B):891-8. Epub 2014 Nov 11.

State Key Laboratory of Cancer Biology and Xijing Hospital of Digestive Diseases, Xijing Hospital, Fourth Military Medical University, Xi'an, China. Electronic address:

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http://dx.doi.org/10.1016/j.canlet.2014.10.036DOI Listing
January 2015

Loss of vinculin and membrane-bound β-catenin promotes metastasis and predicts poor prognosis in colorectal cancer.

Mol Cancer 2014 Dec 11;13:263. Epub 2014 Dec 11.

Department of Gastroenterology & State Key Laboratory of Cancer Biology, Xijing Hospital, The Fourth Military Medical University, Xi'an 710032, China.

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http://dx.doi.org/10.1186/1476-4598-13-263DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4320448PMC
December 2014

Hypoxia-inducible lncRNA-AK058003 promotes gastric cancer metastasis by targeting γ-synuclein.

Neoplasia 2014 Dec;16(12):1094-106

Department of Oncology, Tangdu Hospital, Fourth Military Medical University, 1 Xinsi Road, Xi'an 710038, China. Electronic address:

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http://dx.doi.org/10.1016/j.neo.2014.10.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4309257PMC
December 2014