Publications by authors named "Kai Tan"

100Publications

Enteroviral 3C protease activates the human NLRP1 inflammasome in airway epithelia.

Science 2020 Oct 22. Epub 2020 Oct 22.

Institute of Medical Biology, Agency of Science, Technological and Research, 8A Biomedical Grove, #06-06 Immunos, 138648, Singapore.

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http://dx.doi.org/10.1126/science.aay2002DOI Listing
October 2020

Correlation of microbiota in the gut of fish species and water.

3 Biotech 2020 Nov 12;10(11):472. Epub 2020 Oct 12.

Department of Animal Nutrition, Hunan Institute of Microbiology, No 18 Xinkaipu Road, Changsha, 410009 Hunan China.

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http://dx.doi.org/10.1007/s13205-020-02461-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7550513PMC
November 2020

Lactobacillus reuteri DSM 17938 and ATCC PTA 5289 ameliorates chemotherapy-induced oral mucositis.

Sci Rep 2020 Oct 1;10(1):16189. Epub 2020 Oct 1.

Faculty of Dentistry, National University of Singapore, 9 Lower Kent Ridge Road, Singapore, 119085, Singapore.

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http://dx.doi.org/10.1038/s41598-020-73292-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7530769PMC
October 2020

p63Krt5 basal cells are increased in the squamous metaplastic epithelium of patients with radiation-induced chronic Rhinosinusitis.

Radiat Oncol 2020 Sep 25;15(1):222. Epub 2020 Sep 25.

Department of Otolaryngology, National University of Singapore, 1E Kent Ridge Rd, Singapore, 119228, Singapore.

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http://dx.doi.org/10.1186/s13014-020-01656-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7517817PMC
September 2020

Hypoxia-induced factor-1α induces NLRP3 expression by M1 macrophages in noneosinophilic chronic rhinosinusitis with nasal polyps.

Allergy 2020 Aug 27. Epub 2020 Aug 27.

Department of Otolaryngology, People's Hospital of Tibet Autonomous Region, Lhasa, China.

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http://dx.doi.org/10.1111/all.14571DOI Listing
August 2020

Diverse noncoding mutations contribute to deregulation of cis-regulatory landscape in pediatric cancers.

Sci Adv 2020 Jul 24;6(30):eaba3064. Epub 2020 Jul 24.

Division of Oncology and Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1126/sciadv.aba3064DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7439310PMC
July 2020

Synthesis of Amino Acids by Base-Enhanced Photoredox Decarboxylative Alkylation of Aldimines.

J Org Chem 2020 Aug 17;85(15):9944-9954. Epub 2020 Jul 17.

Center for Pharmaceutical Sciences and Engineering, Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming 650500, China.

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http://dx.doi.org/10.1021/acs.joc.0c01246DOI Listing
August 2020

Association of microbiota in the stomach of and its cultured soil.

3 Biotech 2020 Jul 26;10(7):319. Epub 2020 Jun 26.

College of Mathematics and Finance, Hunan University of Humanities, Science and Technology, Dixing Road 487, Louxing District, Loudi, 417000 Hunan China.

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http://dx.doi.org/10.1007/s13205-020-02313-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7320126PMC
July 2020

Transcriptional regulatory network controlling the ontogeny of hematopoietic stem cells.

Genes Dev 2020 07 4;34(13-14):950-964. Epub 2020 Jun 4.

Division of Oncology, Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, USA.

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http://dx.doi.org/10.1101/gad.338202.120DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7328518PMC
July 2020

Pterostilbene complexed with cyclodextrin exerts antimicrobial and anti-inflammatory effects.

Sci Rep 2020 06 3;10(1):9072. Epub 2020 Jun 3.

Faculty of Dentistry, National University of Singapore, Singapore, Singapore.

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http://dx.doi.org/10.1038/s41598-020-66031-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7271226PMC
June 2020

Scandium Tetrahedron Supported by H Anion and CN Pentaanion inside Fullerene C.

Inorg Chem 2020 Jun 21;59(12):8284-8290. Epub 2020 May 21.

Beijing National Laboratory for Molecular Sciences, Key Laboratory of Molecular Nanostructure and Nanotechnology, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China.

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http://dx.doi.org/10.1021/acs.inorgchem.0c00681DOI Listing
June 2020

Growth differentiation factor-15 is a prognostic marker in patients with intermediate coronary artery disease.

J Geriatr Cardiol 2020 Apr;17(4):210-216

Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University and Beijing Institute of Heart, Lung and Blood Vessel Diseases, Beijing, China.

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http://dx.doi.org/10.11909/j.issn.1671-5411.2020.04.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7189259PMC
April 2020

Long-term defects of nasal epithelium barrier functions in patients with nasopharyngeal carcinoma post chemo-radiotherapy.

Radiother Oncol 2020 Jul 6;148:116-125. Epub 2020 Apr 6.

Department of Otolaryngology, National University of Singapore, National University Health System, Singapore. Electronic address:

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http://dx.doi.org/10.1016/j.radonc.2020.03.038DOI Listing
July 2020

scATAC-pro: a comprehensive workbench for single-cell chromatin accessibility sequencing data.

Genome Biol 2020 04 20;21(1):94. Epub 2020 Apr 20.

Center for Childhood Cancer Research, The Children's Hospital of Philadelphia, Philadelphia, PA, 19104, USA.

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http://dx.doi.org/10.1186/s13059-020-02008-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7169039PMC
April 2020

FGF2, an Immunomodulatory Factor in Asthma and Chronic Obstructive Pulmonary Disease (COPD).

Front Cell Dev Biol 2020 2;8:223. Epub 2020 Apr 2.

Guangdong Provincial Key Laboratory of Biomedical Imaging and Guangdong Provincial Engineering Research Center of Molecular Imaging, The Fifth Affiliated Hospital, Sun Yat-sen University, Zhuhai, China.

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http://dx.doi.org/10.3389/fcell.2020.00223DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7142218PMC
April 2020

Thalidomide with blockade of co-stimulatory molecules prolongs the survival of alloantigen-primed mice with cardiac allografts.

BMC Immunol 2020 04 16;21(1):19. Epub 2020 Apr 16.

Organ Transplantation institute, School of Medicine, Xiamen University, Xiamen, 361100, Fujian, China.

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http://dx.doi.org/10.1186/s12865-020-00352-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7164359PMC
April 2020

[Verification of accuracy of warfarin stable dose prediction models in Shandong population].

Zhonghua Yi Xue Yi Chuan Xue Za Zhi 2020 Apr;37(4):401-404

Qingdao Fuwai Cardiovascular Hospital, Qingdao, Shandong 266034, China.

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http://dx.doi.org/10.3760/cma.j.issn.1003-9406.2020.04.009DOI Listing
April 2020

Athermal Shape Memory Effect in Magnetoactive Elastomers.

ACS Appl Mater Interfaces 2020 Apr 26;12(14):16930-16936. Epub 2020 Mar 26.

State Key Laboratory for Strength and Vibration of Mechanical Structures, Xi'an Jiaotong University, Xi'an 710049, P. R. China.

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http://dx.doi.org/10.1021/acsami.0c01453DOI Listing
April 2020

Dissecting the Tumor-Immune Landscape in Chimeric Antigen Receptor T-cell Therapy: Key Challenges and Opportunities for a Systems Immunology Approach.

Clin Cancer Res 2020 Jul 3;26(14):3505-3513. Epub 2020 Mar 3.

Division of Oncology, Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.

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http://dx.doi.org/10.1158/1078-0432.CCR-19-3888DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7367708PMC
July 2020

Proteomics profiling of epithelium-derived exosomes from nasal polyps revealed signaling functions affecting cellular proliferation.

Respir Med 2020 02 8;162:105871. Epub 2020 Jan 8.

Department of Otolaryngology, The First Affiliated Hospital of Sun Yat-sen University, Sun Yat-sen University. Guangzhou, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.rmed.2020.105871DOI Listing
February 2020

Mechanisms of Entrectinib Resistance in a Neuroblastoma Xenograft Model.

Mol Cancer Ther 2020 03 23;19(3):920-926. Epub 2019 Dec 23.

Division of Oncology, Children's Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania.

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http://dx.doi.org/10.1158/1535-7163.MCT-18-1044DOI Listing
March 2020

Spatial Genome Re-organization between Fetal and Adult Hematopoietic Stem Cells.

Cell Rep 2019 12;29(12):4200-4211.e7

Division of Oncology and Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA; Department of Cell and Developmental Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2019.11.065DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7262670PMC
December 2019

Biotransformation of Piceatannol, a Dietary Resveratrol Derivative: Promises to Human Health.

Mol Nutr Food Res 2020 01 7;64(2):e1900905. Epub 2020 Jan 7.

Department of Pharmacy, National University of Singapore, 18 Science Drive 4, Singapore, 117543.

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http://dx.doi.org/10.1002/mnfr.201900905DOI Listing
January 2020

An Integrated Analysis of Radial Spoke Head and Outer Dynein Arm Protein Defects and Ciliogenesis Abnormality in Nasal Polyps.

Front Genet 2019 13;10:1083. Epub 2019 Nov 13.

Department of Otolaryngology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.

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http://dx.doi.org/10.3389/fgene.2019.01083DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6863926PMC
November 2019

Bacterial diversity in intestinal mucosa of antibiotic-associated diarrhea mice.

3 Biotech 2019 Dec 9;9(12):444. Epub 2019 Nov 9.

1Hunan University of Chinese Medicine, Xueshi Road 300, Yuelu District, Changsha, 410208 Hunan Province China.

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http://dx.doi.org/10.1007/s13205-019-1967-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6842370PMC
December 2019

Chemoselectivity in Gold(I)-Catalyzed Propargyl Ester Reactions: Insights From DFT Calculations.

Front Chem 2019 6;7:609. Epub 2019 Sep 6.

State Key Laboratory of Physical Chemistry of Solid Surfaces, Fujian Provincial Key Laboratory for Theoretical and Computational Chemistry, Department of Chemistry, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen, China.

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http://dx.doi.org/10.3389/fchem.2019.00609DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6743037PMC
September 2019

Antibiotics Used in Regenerative Endodontics Modify Immune Response of Macrophages to Bacterial Infection.

J Endod 2019 Nov 19;45(11):1349-1356. Epub 2019 Sep 19.

Faculty of Dentistry, National University of Singapore, Singapore. Electronic address:

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http://dx.doi.org/10.1016/j.joen.2019.08.001DOI Listing
November 2019

Financial discussions during cancer clinic consultations in Asia: Show me the money.

Asia Pac J Clin Oncol 2020 02 16;16(1):86-87. Epub 2019 Sep 16.

Lien Centre for Palliative Care, Duke-NUS Medical School, Singapore, Singapore.

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http://dx.doi.org/10.1111/ajco.13237DOI Listing
February 2020

Outcomes following selective fetoscopic laser ablation for twin-to-twin transfusion syndrome: a single-centre experience.

Singapore Med J 2019 Sep 6. Epub 2019 Sep 6.

Department of Maternal Fetal Medicine, KK Women's and Children's Hospital, Singapore.

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http://dx.doi.org/10.11622/smedj.2019107DOI Listing
September 2019

A lineage-resolved molecular atlas of embryogenesis at single-cell resolution.

Science 2019 09 5;365(6459). Epub 2019 Sep 5.

Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.

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http://dx.doi.org/10.1126/science.aax1971DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7428862PMC
September 2019

PD-1 expression and its significance in tumour microenvironment of hepatocellular carcinoma.

Transl Gastroenterol Hepatol 2019 2;4:51. Epub 2019 Jul 2.

Translational Immunology Institute (TII), SingHealth Duke-NUS Academic Medical Centre, Singapore.

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http://tgh.amegroups.com/article/view/5156/html
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http://dx.doi.org/10.21037/tgh.2019.06.08DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6691086PMC
July 2019

Insights into Early Recovery from Influenza Pneumonia by Spatial and Temporal Quantification of Putative Lung Regenerating Cells and by Lung Proteomics.

Cells 2019 08 26;8(9). Epub 2019 Aug 26.

Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117545, Singapore.

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http://dx.doi.org/10.3390/cells8090975DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6769472PMC
August 2019

Microarray Assay Reveals Ciliary Abnormalities of the Allergic Nasal Mucosa.

Am J Rhinol Allergy 2020 Jan 26;34(1):50-58. Epub 2019 Aug 26.

Department of Otolaryngology, Zhujiang Hospital, Southern Medical University, Guangzhou, China.

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http://dx.doi.org/10.1177/1945892419871795DOI Listing
January 2020

miRNA-9 inhibits apoptosis and promotes proliferation in angiotensin II-induced human umbilical vein endothelial cells by targeting MDGA2.

Rev Cardiovasc Med 2019 Jun;20(2):101-108

Department of Cardiology, Affiliated Hospital of Qingdao University, Qingdao, 266003, P. R. China.

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http://dx.doi.org/10.31083/j.rcm.2019.02.514DOI Listing
June 2019

The effect of genotype-guided antiplatelet therapy on outcomes of selective percutaneous coronary intervention patients: an observational study.

Per Med 2019 07 19;16(4):301-312. Epub 2019 Jul 19.

Department of Cardiology, Qingdao Fu Wai Hospital of Cardiovascular Diseases, Qingdao 266034, China.

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http://dx.doi.org/10.2217/pme-2018-0087DOI Listing
July 2019

Upregulation of cell-surface mucin MUC15 in human nasal epithelial cells upon influenza A virus infection.

BMC Infect Dis 2019 Jul 15;19(1):622. Epub 2019 Jul 15.

Department of Otolaryngology, Yong Loo Lin School of Medicine, National University of Singapore, 1E Kent Ridge Road, Singapore, 119228, Singapore.

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http://dx.doi.org/10.1186/s12879-019-4213-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6631914PMC
July 2019

Distribution and Determinants of Dermatophagoides Mites Sensitization ofAllergic Rhinitis and Allergic Asthma in China.

Int Arch Allergy Immunol 2019 17;180(1):17-27. Epub 2019 May 17.

Department of Otolaryngology Head and Neck Surgery, The Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China,

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https://www.karger.com/Article/FullText/499409
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http://dx.doi.org/10.1159/000499409DOI Listing
September 2019

Optimal control nodes in disease-perturbed networks as targets for combination therapy.

Nat Commun 2019 05 16;10(1):2180. Epub 2019 May 16.

Division of Oncology and Center for Childhood Cancer Research, 4004 CTRB, Children's Hospital of Philadelphia, 3501 Civic Center Boulevard, Philadelphia, PA, 19104, USA.

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http://dx.doi.org/10.1038/s41467-019-10215-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6522545PMC
May 2019

SCRABBLE: single-cell RNA-seq imputation constrained by bulk RNA-seq data.

Genome Biol 2019 05 6;20(1):88. Epub 2019 May 6.

Division of Oncology and Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Philadelphia, PA, 19104, USA.

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https://genomebiology.biomedcentral.com/articles/10.1186/s13
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http://dx.doi.org/10.1186/s13059-019-1681-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6501316PMC
May 2019

Flexoelectret: An Electret with a Tunable Flexoelectriclike Response.

Phys Rev Lett 2019 Apr;122(14):148001

State Key Laboratory for Strength and Vibration of Mechanical Structures, School of Aerospace Engineering, Xi'an Jiaotong University, Xi'an 710049, China.

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https://link.aps.org/doi/10.1103/PhysRevLett.122.148001
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http://dx.doi.org/10.1103/PhysRevLett.122.148001DOI Listing
April 2019

The Pediatric Cell Atlas: Defining the Growth Phase of Human Development at Single-Cell Resolution.

Dev Cell 2019 04 28;49(1):10-29. Epub 2019 Mar 28.

Department of Biomedical Informatics, University of Cincinnati College of Medicine, and Cincinnati Children's Hospital Medical Center, Division of Biomedical Informatics, Cincinnati, OH 45229, USA.

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http://dx.doi.org/10.1016/j.devcel.2019.03.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6616346PMC
April 2019

Risk variants disrupting enhancers of T1 and T cells in type 1 diabetes.

Proc Natl Acad Sci U S A 2019 04 25;116(15):7581-7590. Epub 2019 Mar 25.

Division of Oncology, Children's Hospital of Philadelphia, Philadelphia, PA 19104;

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http://dx.doi.org/10.1073/pnas.1815336116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6462079PMC
April 2019

Sulfur Moiety as a Double-Edged Sword for Realizing Ultrafine Supported Metal Nanoclusters with a Cationic Nature.

ACS Appl Mater Interfaces 2019 Mar 13;11(12):11317-11326. Epub 2019 Mar 13.

State Key Laboratory of Physical Chemistry of Solid Surfaces, National Engineering Laboratory for Green Chemical Productions of Alcohols-Ethers-Esters, iChEM, College of Chemistry and Chemical Engineering , Xiamen University , No. 422, Siming South Road , Siming District, Xiamen 361005 , China.

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http://dx.doi.org/10.1021/acsami.8b18952DOI Listing
March 2019

Novel Use of Capturex Device and Reliant Balloon for Inferior Vena Cava Tumor Thrombectomy: A Case Report and Review of Literature.

Vasc Endovascular Surg 2019 May 3;53(4):351-354. Epub 2019 Mar 3.

1 Division of vascular surgery, Changi General Hospital, Singapore.

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http://dx.doi.org/10.1177/1538574419831834DOI Listing
May 2019

Access to Multisubstituted 2(5 H)-Furanones Using Hydrogen Bonding-Promoted Ring-Closing Metathesis and Polyamine Workup.

J Org Chem 2019 03 5;84(6):3419-3430. Epub 2019 Mar 5.

Faculty of Life Science and Technology , Kunming University of Science and Technology , Kunming 650500 , China.

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http://dx.doi.org/10.1021/acs.joc.8b03293DOI Listing
March 2019

Aberrant localization of FOXJ1 correlates with the disease severity and comorbidities in patients with nasal polyps.

Allergy Asthma Clin Immunol 2018 14;14:71. Epub 2018 Nov 14.

2Department of Otolaryngology, National University of Singapore, National University Health System, Singapore, Singapore.

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http://dx.doi.org/10.1186/s13223-018-0296-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6234688PMC
November 2018

RUNX1 and the endothelial origin of blood.

Exp Hematol 2018 12 31;68:2-9. Epub 2018 Oct 31.

Department of Cell and Developmental Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA; Abramson Family Cancer Research Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S0301472X183087
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http://dx.doi.org/10.1016/j.exphem.2018.10.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6494457PMC
December 2018

Decreased hospital charges and postoperative pain in septoplasty by application of enhanced recovery after surgery.

Ther Clin Risk Manag 2018 4;14:1871-1877. Epub 2018 Oct 4.

Department of Otolaryngology, Allergy Center, The Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai, People's Republic of China,

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http://dx.doi.org/10.2147/TCRM.S173687DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6174903PMC
October 2018

Metal-catalyzed alkyne oxidation/CH functionalization: Effects of oxidant, temperature, and metal catalyst on chemoselectivity.

J Comput Chem 2019 Apr 9;40(9):1038-1044. Epub 2018 Oct 9.

State Key Laboratory of Physical Chemistry of Solid Surface & Fujian Provincial Key Laboratory for Theoretical and Computational Chemistry, Department of Chemistry, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen, 361005, People's Republic of China.

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http://doi.wiley.com/10.1002/jcc.25591
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http://dx.doi.org/10.1002/jcc.25591DOI Listing
April 2019

H3N2 influenza virus infection enhances oncostatin M expression in human nasal epithelium.

Exp Cell Res 2018 10 22;371(2):322-329. Epub 2018 Aug 22.

Department of Otolaryngology, Yong Loo Lin School of Medicine, National University of Singapore, National University Health System, Singapore, Singapore. Electronic address:

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http://dx.doi.org/10.1016/j.yexcr.2018.08.022DOI Listing
October 2018

Motile Ciliary Disorders in Chronic Airway Inflammatory Diseases: Critical Target for Interventions.

Curr Allergy Asthma Rep 2018 07 26;18(9):48. Epub 2018 Jul 26.

Department of Otolaryngology, Yong Loo Lin School of Medicine, National University of Singapore, 1E Kent Ridge Rd, Singapore, 119228, Singapore.

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http://dx.doi.org/10.1007/s11882-018-0802-xDOI Listing
July 2018

Sinus computed tomography predicts clinical response to corticosteroids in chronic rhinosinusitis with nasal polyps.

Clin Transl Allergy 2018 2;8:24. Epub 2018 Jul 2.

2Otorhinolaryngology Hospital, The First Affiliated Hospital, Sun Yat-sen University, 58 Zhongshan Road II, Guangzhou, 510080 Guangdong China.

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http://dx.doi.org/10.1186/s13601-018-0211-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6027579PMC
July 2018

Phospholipase PLA2G6, a Parkinsonism-Associated Gene, Affects Vps26 and Vps35, Retromer Function, and Ceramide Levels, Similar to α-Synuclein Gain.

Cell Metab 2018 10 14;28(4):605-618.e6. Epub 2018 Jun 14.

Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA; Program in Developmental Biology, Baylor College of Medicine, Houston, TX 77030, USA; Howard Hughes Medical Institute, Baylor College of Medicine, Houston, TX 77030, USA; Department of Neuroscience, Baylor College of Medicine, Houston, TX 77030, USA; Jan and Dan Duncan Neurological Research Institute, Texas Children's Hospital, Houston, TX 77030, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cmet.2018.05.019DOI Listing
October 2018

LncRNA HOTAIR contributes to the malignancy of hepatocellular carcinoma by enhancing epithelial-mesenchymal transition via sponging miR-23b-3p from ZEB1.

Gene 2018 Sep 17;670:114-122. Epub 2018 May 17.

Department of General Surgery, Tangdu Hospital, the Fourth Military Medical University, Shaanxi 710038, Xi'an, China. Electronic address:

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http://dx.doi.org/10.1016/j.gene.2018.05.061DOI Listing
September 2018

Ari-1 Regulates Myonuclear Organization Together with Parkin and Is Associated with Aortic Aneurysms.

Dev Cell 2018 04;45(2):226-244.e8

Program in Developmental Biology, Baylor College of Medicine (BCM), Houston, TX 77030, USA; Department of Molecular and Human Genetics, BCM, Houston, TX 77030, USA; Howard Hughes Medical Institute, BCM, Houston, TX 77030, USA; Jan and Dan Duncan Neurological Research Institute, Texas Children's Hospital (TCH), Houston, TX 77030, USA; Department of Neuroscience, BCM, Houston, TX 77030, USA. Electronic address:

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http://dx.doi.org/10.1016/j.devcel.2018.03.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5920516PMC
April 2018

Downregulation and Aberrant Localization of Forkhead Box J1 in Allergic Nasal Mucosa.

Int Arch Allergy Immunol 2018 10;176(2):115-123. Epub 2018 Apr 10.

Department of Otolaryngology, National University of Singapore, National University Health System, Singapore, Singapore.

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http://dx.doi.org/10.1159/000488014DOI Listing
June 2018

Identifying noncoding risk variants using disease-relevant gene regulatory networks.

Nat Commun 2018 02 16;9(1):702. Epub 2018 Feb 16.

Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA.

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http://dx.doi.org/10.1038/s41467-018-03133-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5816022PMC
February 2018

CD151, a novel host factor of nuclear export signaling in influenza virus infection.

J Allergy Clin Immunol 2018 05 21;141(5):1799-1817. Epub 2017 Dec 21.

Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2017.11.032DOI Listing
May 2018

Recombinant human adenovirus-p53 improves the outcome of mid-late stage pancreatic cancer via arterial infusion.

Oncol Lett 2017 Dec 25;14(6):6829-6832. Epub 2017 Sep 25.

Department of Hepatobiliary Surgery, Taizhou Central Hospital, Taizhou, Zhejiang 318000, P.R. China.

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http://dx.doi.org/10.3892/ol.2017.7058DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5696714PMC
December 2017

Gender-Specific Reference Charts of Fetal Head Circumference in a Singaporean Population.

Ann Acad Med Singap 2017 Oct;46(10):367-373

Department of Maternal Fetal Medicine, KK Women's and Children's Hospital, Singapore.

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October 2017

Absence or mislocalization of DNAH5 is a characteristic marker for motile ciliary abnormality in nasal polyps.

Laryngoscope 2018 03 17;128(3):E97-E104. Epub 2017 Nov 17.

Department of Otolaryngology, National University of Singapore, National University Health System, Singapore, Singapore.

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http://dx.doi.org/10.1002/lary.26983DOI Listing
March 2018

Transposon for Efficient Random Mutagenesis in .

Front Microbiol 2017 26;8:1842. Epub 2017 Sep 26.

Faculty of Dentistry, National University of Singapore, Singapore, Singapore.

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http://dx.doi.org/10.3389/fmicb.2017.01842DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5622930PMC
September 2017

Identifying topologically associating domains and subdomains by Gaussian Mixture model And Proportion test.

Nat Commun 2017 09 14;8(1):535. Epub 2017 Sep 14.

Department of Biomedical and Health Informatics, Children's Hospital of Philadelphia, Philadelphia, PA, 19104, USA.

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http://dx.doi.org/10.1038/s41467-017-00478-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5599511PMC
September 2017

Prostaglandin E1 and Its Analog Misoprostol Inhibit Human CML Stem Cell Self-Renewal via EP4 Receptor Activation and Repression of AP-1.

Cell Stem Cell 2017 09 30;21(3):359-373.e5. Epub 2017 Aug 30.

Department of Microbiology and Immunology, Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USA. Electronic address:

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http://dx.doi.org/10.1016/j.stem.2017.08.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5678929PMC
September 2017

Intrahepatic CD206 macrophages contribute to inflammation in advanced viral-related liver disease.

J Hepatol 2017 09 5;67(3):490-500. Epub 2017 May 5.

Program in Emerging Infectious Diseases, Duke-NUS Medical School, 8 College Road, Singapore 169857, Singapore; Singapore Immunology Network, A*STAR, 8A Biomedical Grove, Immunos Building, Level 4, Singapore 138648, Singapore. Electronic address:

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http://dx.doi.org/10.1016/j.jhep.2017.04.023DOI Listing
September 2017

Impact of Respiratory Virus Infections in Exacerbation of Acute and Chronic Rhinosinusitis.

Curr Allergy Asthma Rep 2017 Apr;17(4):24

Department of Otolaryngology, Yong Loo Lin School of Medicine, National University of Singapore, 1E Kent Ridge Road, Singapore, 119228, Singapore.

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http://dx.doi.org/10.1007/s11882-017-0693-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7088794PMC
April 2017

Effects of root debridement and adjunctive photodynamic therapy in residual pockets of patients on supportive periodontal therapy: A randomized split-mouth trial.

Photodiagnosis Photodyn Ther 2017 Jun 31;18:342-348. Epub 2017 Mar 31.

Discipline of Periodontology, Faculty of Dentistry, National University of Singapore, Republic of Singapore. Electronic address:

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http://dx.doi.org/10.1016/j.pdpdt.2017.03.017DOI Listing
June 2017

Prediction of neonatal respiratory morbidity by quantitative ultrasound lung texture analysis: a multicenter study.

Am J Obstet Gynecol 2017 08 23;217(2):196.e1-196.e14. Epub 2017 Mar 23.

BCNatal, Barcelona Center for Maternal-Fetal and Neonatal Medicine (Hospital Clínic and Hospital Sant Joan de Déu), IDIBAPS, University of Barcelona, Barcelona, Spain; Centre for Biomedical Research on Rare Diseases (Centro de Investigación Biomédica en Red Enfermedades Raras), Barcelona, Spain.

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http://dx.doi.org/10.1016/j.ajog.2017.03.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5625293PMC
August 2017

Prediction of risk of cardiovascular events in patients with mild to moderate coronary artery lesions using naïve Bayesian networks.

J Geriatr Cardiol 2016 Nov;13(11):899-905

Beijing Anzhen Hospital, Capital Medical University, Beijing Institute of Heart, Lung and Blood Vessel Diseases, Beijing, China.

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http://dx.doi.org/10.11909/j.issn.1671-5411.2016.11.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5253406PMC
November 2016

MicroRNA-146a induction during influenza H3N2 virus infection targets and regulates TRAF6 levels in human nasal epithelial cells (hNECs).

Exp Cell Res 2017 03 25;352(2):184-192. Epub 2017 Jan 25.

Department of Otolaryngology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore. Electronic address:

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http://dx.doi.org/10.1016/j.yexcr.2017.01.011DOI Listing
March 2017

Magnetic compression anastomosis for enteroenterostomy under peritonitis conditions in dogs.

J Surg Res 2017 02 4;208:60-67. Epub 2016 Sep 4.

Department of General Surgery, Tangdu Hospital of the Fourth Military Medical University, Xi'an, P. R. China. Electronic address:

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http://dx.doi.org/10.1016/j.jss.2016.08.091DOI Listing
February 2017

CD8 T Cells Utilize Highly Dynamic Enhancer Repertoires and Regulatory Circuitry in Response to Infections.

Immunity 2016 12 13;45(6):1341-1354. Epub 2016 Dec 13.

Department of Microbiology, Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USA; Interdisciplinary Immunology Graduate Program, University of Iowa, Iowa City, IA 52242, USA; Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S10747613163048
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http://dx.doi.org/10.1016/j.immuni.2016.11.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5304416PMC
December 2016

The Danger Signal Extracellular ATP Is an Inducer of Biofilm Dispersal.

Front Cell Infect Microbiol 2016 17;6:155. Epub 2016 Nov 17.

Faculty of Dentistry, National University of Singapore Singapore, Singapore.

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http://dx.doi.org/10.3389/fcimb.2016.00155DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5112537PMC
August 2017

Conditional knockout of N-WASP in mouse fibroblast caused keratinocyte hyper proliferation and enhanced wound closure.

Sci Rep 2016 12 2;6:38109. Epub 2016 Dec 2.

School of Biological Sciences, Nanyang Technological University, 60 Nanyang Drive, Singapore 637551, Republic of Singapore.

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http://dx.doi.org/10.1038/srep38109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133560PMC
December 2016

Loss of Frataxin activates the iron/sphingolipid/PDK1/Mef2 pathway in mammals.

Elife 2016 11 30;5. Epub 2016 Nov 30.

Program in Developmental Biology, Baylor College of Medicine, Houston, United States.

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http://dx.doi.org/10.7554/eLife.20732DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5130293PMC
November 2016

Telomere length is regulated by FGF-2 in human embryonic stem cells and affects the life span of its differentiated progenies.

Biogerontology 2017 02 18;18(1):69-84. Epub 2016 Oct 18.

Faculty of Dentistry, National University of Singapore, 11 Lower Kent Ridge Road, Singapore, 119083, Singapore.

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http://link.springer.com/10.1007/s10522-016-9662-8
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http://dx.doi.org/10.1007/s10522-016-9662-8DOI Listing
February 2017

Pterostilbene inhibits hepatocellular carcinoma through p53/SOD2/ROS-mediated mitochondrial apoptosis.

Oncol Rep 2016 Dec 5;36(6):3233-3240. Epub 2016 Oct 5.

Department of Obstetrics and Gynecology, Xi'an Central Hospital, Xi'an, Shaanxi 710003, P.R. China.

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http://dx.doi.org/10.3892/or.2016.5151DOI Listing
December 2016

Innate Immune Response of Human Embryonic Stem Cell-Derived Fibroblasts and Mesenchymal Stem Cells to Periodontopathogens.

Stem Cells Int 2016 25;2016:8905365. Epub 2016 Aug 25.

Discipline of Oral Sciences, Faculty of Dentistry, National University of Singapore, Singapore; NUS Graduate School for Integrative Sciences and Engineering, Singapore; Tissue Engineering Program, Life Sciences Institute, National University of Singapore, Singapore.

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http://dx.doi.org/10.1155/2016/8905365DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5014959PMC
September 2016