Kaare Christensen

Kaare Christensen

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Kaare Christensen

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Sex Differences in Comorbidity and Frailty in Europe.

Int J Public Health 2019 Sep 24;64(7):1025-1036. Epub 2019 Jun 24.

Epidemiology, Biostatistics and Biodemography, Department of Public Health, University of Southern Denmark, J. B. Winsløws Vej 9B, 5000, Odense C, Denmark.

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http://dx.doi.org/10.1007/s00038-019-01270-9DOI Listing
September 2019

Gender differences in cognitive function and grip strength: a cross-national comparison of four European regions.

Eur J Public Health 2019 Aug;29(4):667-674

Unit of Epidemiology, Biostatistics and Biodemography, Department of Public Health, University of Southern Denmark, Odense, Denmark.

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http://dx.doi.org/10.1093/eurpub/cky266DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6660112PMC
August 2019

A nonsynonymous mutation in PLCG2 reduces the risk of Alzheimer's disease, dementia with Lewy bodies and frontotemporal dementia, and increases the likelihood of longevity.

Authors:
Sven J van der Lee Olivia J Conway Iris Jansen Minerva M Carrasquillo Luca Kleineidam Erik van den Akker Isabel Hernández Kristel R van Eijk Najada Stringa Jason A Chen Anna Zettergren Till F M Andlauer Monica Diez-Fairen Javier Simon-Sanchez Alberto Lleó Henrik Zetterberg Marianne Nygaard Cornelis Blauwendraat Jeanne E Savage Jonas Mengel-From Sonia Moreno-Grau Michael Wagner Juan Fortea Michael J Keogh Kaj Blennow Ingmar Skoog Manuel A Friese Olga Pletnikova Miren Zulaica Carmen Lage Itziar de Rojas Steffi Riedel-Heller Ignacio Illán-Gala Wei Wei Bernard Jeune Adelina Orellana Florian Then Bergh Xue Wang Marc Hulsman Nina Beker Niccolo Tesi Christopher M Morris Begoña Indakoetxea Lyduine E Collij Martin Scherer Estrella Morenas-Rodríguez James W Ironside Bart N M van Berckel Daniel Alcolea Heinz Wiendl Samantha L Strickland Pau Pastor Eloy Rodríguez Rodríguez Bradley F Boeve Ronald C Petersen Tanis J Ferman Jay A van Gerpen Marcel J T Reinders Ryan J Uitti Lluís Tárraga Wolfgang Maier Oriol Dols-Icardo Amit Kawalia Maria Carolina Dalmasso Mercè Boada Uwe K Zettl Natasja M van Schoor Marian Beekman Mariet Allen Eliezer Masliah Adolfo López de Munain Alexander Pantelyat Zbigniew K Wszolek Owen A Ross Dennis W Dickson Neill R Graff-Radford David Knopman Rosa Rademakers Afina W Lemstra Yolande A L Pijnenburg Philip Scheltens Thomas Gasser Patrick F Chinnery Bernhard Hemmer Martijn A Huisman Juan Troncoso Fermin Moreno Ellen A Nohr Thorkild I A Sørensen Peter Heutink Pascual Sánchez-Juan Danielle Posthuma Jordi Clarimón Kaare Christensen Nilüfer Ertekin-Taner Sonja W Scholz Alfredo Ramirez Agustín Ruiz Eline Slagboom Wiesje M van der Flier Henne Holstege

Acta Neuropathol 2019 Aug 27;138(2):237-250. Epub 2019 May 27.

Alzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1007/s00401-019-02026-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6660501PMC
August 2019

A meta-analysis of genome-wide association studies identifies multiple longevity genes.

Nat Commun 2019 Aug 14;10(1):3669. Epub 2019 Aug 14.

NHLBI's and Boston University's Framingham Heart Study, Framingham, MA, 01702, USA.

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http://dx.doi.org/10.1038/s41467-019-11558-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6694136PMC
August 2019

Epigenetic signature of preterm birth in adult twins.

Clin Epigenetics 2018 27;10:87. Epub 2018 Jun 27.

1Epidemiology and Biostatistics, Department of Public Health, Faculty of Health Science, University of Southern Denmark, J. B. Winsløws Vej 9B, DK-5000 Odense, Denmark.

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http://dx.doi.org/10.1186/s13148-018-0518-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6020425PMC
July 2019

Use of β2-adrenoreceptor agonist and antagonist drugs and risk of Parkinson disease.

Neurology 2019 Jul 24;93(2):e135-e142. Epub 2019 May 24.

From the Department of Psychiatry and Psychotherapy (F.H.), Ludwig-Maximilians-Universität München, Germany; Department of Neurology (F.H., G.K., G.D.), UKSH, Christian-Albrechts-University Kiel, Germany; Unit of Epidemiology, Biostatistics and Biodemography (M.W., K.C.), Danish Twin Registry (M.W., K.C.), Danish Aging Research Center (M.W., K.C.), and Department of Clinical Research (M.B.) and Clinical Pharmacology and Pharmacy (A.P.), Department of Public Health, University of Southern Denmark, Odense; Department of Neurology (G.U.H.), Hannover Medical School, Germany; Department of Neurology (G.U.H., T.W.R.), Technical University of Munich; German Center for Neurodegenerative Diseases (G.U.H., T.W.R.); Munich Cluster for Systems Neurology (G.U.H., T.W.R.), Germany; and Departments of Neurology (M.B.), Clinical Genetics (K.C.), and Clinical Biochemistry and Pharmacology (K.C.), Odense University Hospital, Denmark.

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http://dx.doi.org/10.1212/WNL.0000000000007694DOI Listing
July 2019

A catalog of genetic loci associated with kidney function from analyses of a million individuals.

Authors:
Matthias Wuttke Yong Li Man Li Karsten B Sieber Mary F Feitosa Mathias Gorski Adrienne Tin Lihua Wang Audrey Y Chu Anselm Hoppmann Holger Kirsten Ayush Giri Jin-Fang Chai Gardar Sveinbjornsson Bamidele O Tayo Teresa Nutile Christian Fuchsberger Jonathan Marten Massimiliano Cocca Sahar Ghasemi Yizhe Xu Katrin Horn Damia Noce Peter J van der Most Sanaz Sedaghat Zhi Yu Masato Akiyama Saima Afaq Tarunveer S Ahluwalia Peter Almgren Najaf Amin Johan Ärnlöv Stephan J L Bakker Nisha Bansal Daniela Baptista Sven Bergmann Mary L Biggs Ginevra Biino Michael Boehnke Eric Boerwinkle Mathilde Boissel Erwin P Bottinger Thibaud S Boutin Hermann Brenner Marco Brumat Ralph Burkhardt Adam S Butterworth Eric Campana Archie Campbell Harry Campbell Mickaël Canouil Robert J Carroll Eulalia Catamo John C Chambers Miao-Ling Chee Miao-Li Chee Xu Chen Ching-Yu Cheng Yurong Cheng Kaare Christensen Renata Cifkova Marina Ciullo Maria Pina Concas James P Cook Josef Coresh Tanguy Corre Cinzia Felicita Sala Daniele Cusi John Danesh E Warwick Daw Martin H de Borst Alessandro De Grandi Renée de Mutsert Aiko P J de Vries Frauke Degenhardt Graciela Delgado Ayse Demirkan Emanuele Di Angelantonio Katalin Dittrich Jasmin Divers Rajkumar Dorajoo Kai-Uwe Eckardt Georg Ehret Paul Elliott Karlhans Endlich Michele K Evans Janine F Felix Valencia Hui Xian Foo Oscar H Franco Andre Franke Barry I Freedman Sandra Freitag-Wolf Yechiel Friedlander Philippe Froguel Ron T Gansevoort He Gao Paolo Gasparini J Michael Gaziano Vilmantas Giedraitis Christian Gieger Giorgia Girotto Franco Giulianini Martin Gögele Scott D Gordon Daniel F Gudbjartsson Vilmundur Gudnason Toomas Haller Pavel Hamet Tamara B Harris Catharina A Hartman Caroline Hayward Jacklyn N Hellwege Chew-Kiat Heng Andrew A Hicks Edith Hofer Wei Huang Nina Hutri-Kähönen Shih-Jen Hwang M Arfan Ikram Olafur S Indridason Erik Ingelsson Marcus Ising Vincent W V Jaddoe Johanna Jakobsdottir Jost B Jonas Peter K Joshi Navya Shilpa Josyula Bettina Jung Mika Kähönen Yoichiro Kamatani Candace M Kammerer Masahiro Kanai Mika Kastarinen Shona M Kerr Chiea-Chuen Khor Wieland Kiess Marcus E Kleber Wolfgang Koenig Jaspal S Kooner Antje Körner Peter Kovacs Aldi T Kraja Alena Krajcoviechova Holly Kramer Bernhard K Krämer Florian Kronenberg Michiaki Kubo Brigitte Kühnel Mikko Kuokkanen Johanna Kuusisto Martina La Bianca Markku Laakso Leslie A Lange Carl D Langefeld Jeannette Jen-Mai Lee Benjamin Lehne Terho Lehtimäki Wolfgang Lieb Su-Chi Lim Lars Lind Cecilia M Lindgren Jun Liu Jianjun Liu Markus Loeffler Ruth J F Loos Susanne Lucae Mary Ann Lukas Leo-Pekka Lyytikäinen Reedik Mägi Patrik K E Magnusson Anubha Mahajan Nicholas G Martin Jade Martins Winfried März Deborah Mascalzoni Koichi Matsuda Christa Meisinger Thomas Meitinger Olle Melander Andres Metspalu Evgenia K Mikaelsdottir Yuri Milaneschi Kozeta Miliku Pashupati P Mishra Karen L Mohlke Nina Mononen Grant W Montgomery Dennis O Mook-Kanamori Josyf C Mychaleckyj Girish N Nadkarni Mike A Nalls Matthias Nauck Kjell Nikus Boting Ning Ilja M Nolte Raymond Noordam Jeffrey O'Connell Michelle L O'Donoghue Isleifur Olafsson Albertine J Oldehinkel Marju Orho-Melander Willem H Ouwehand Sandosh Padmanabhan Nicholette D Palmer Runolfur Palsson Brenda W J H Penninx Thomas Perls Markus Perola Mario Pirastu Nicola Pirastu Giorgio Pistis Anna I Podgornaia Ozren Polasek Belen Ponte David J Porteous Tanja Poulain Peter P Pramstaller Michael H Preuss Bram P Prins Michael A Province Ton J Rabelink Laura M Raffield Olli T Raitakari Dermot F Reilly Rainer Rettig Myriam Rheinberger Kenneth M Rice Paul M Ridker Fernando Rivadeneira Federica Rizzi David J Roberts Antonietta Robino Peter Rossing Igor Rudan Rico Rueedi Daniela Ruggiero Kathleen A Ryan Yasaman Saba Charumathi Sabanayagam Veikko Salomaa Erika Salvi Kai-Uwe Saum Helena Schmidt Reinhold Schmidt Ben Schöttker Christina-Alexandra Schulz Nicole Schupf Christian M Shaffer Yuan Shi Albert V Smith Blair H Smith Nicole Soranzo Cassandra N Spracklen Konstantin Strauch Heather M Stringham Michael Stumvoll Per O Svensson Silke Szymczak E-Shyong Tai Salman M Tajuddin Nicholas Y Q Tan Kent D Taylor Andrej Teren Yih-Chung Tham Joachim Thiery Chris H L Thio Hauke Thomsen Gudmar Thorleifsson Daniela Toniolo Anke Tönjes Johanne Tremblay Ioanna Tzoulaki André G Uitterlinden Simona Vaccargiu Rob M van Dam Pim van der Harst Cornelia M van Duijn Digna R Velez Edward Niek Verweij Suzanne Vogelezang Uwe Völker Peter Vollenweider Gerard Waeber Melanie Waldenberger Lars Wallentin Ya Xing Wang Chaolong Wang Dawn M Waterworth Wen Bin Wei Harvey White John B Whitfield Sarah H Wild James F Wilson Mary K Wojczynski Charlene Wong Tien-Yin Wong Liang Xu Qiong Yang Masayuki Yasuda Laura M Yerges-Armstrong Weihua Zhang Alan B Zonderman Jerome I Rotter Murielle Bochud Bruce M Psaty Veronique Vitart James G Wilson Abbas Dehghan Afshin Parsa Daniel I Chasman Kevin Ho Andrew P Morris Olivier Devuyst Shreeram Akilesh Sarah A Pendergrass Xueling Sim Carsten A Böger Yukinori Okada Todd L Edwards Harold Snieder Kari Stefansson Adriana M Hung Iris M Heid Markus Scholz Alexander Teumer Anna Köttgen Cristian Pattaro

Nat Genet 2019 06 31;51(6):957-972. Epub 2019 May 31.

Eurac Research, Institute for Biomedicine (affiliated with the University of Lübeck), Bolzano, Italy.

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http://dx.doi.org/10.1038/s41588-019-0407-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6698888PMC
June 2019

Epigenome-wide exploratory study of monozygotic twins suggests differentially methylated regions to associate with hand grip strength.

Biogerontology 2019 Jun 28. Epub 2019 Jun 28.

Epidemiology, Biostatistics and Biodemography, Department of Public Health, University of Southern Denmark, J.B. Winsløws Vej 9B, 5000, Odense C, Denmark.

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http://dx.doi.org/10.1007/s10522-019-09818-1DOI Listing
June 2019

A novel healthy metabolic phenotype developed among a cohort of families enriched for longevity.

Metabolism 2019 May 30;94:28-38. Epub 2019 Jan 30.

Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, USA; Departments of Medicine and Clinical and Translational Science, University of Pittsburgh, Pittsburgh, PA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.metabol.2019.01.010DOI Listing
May 2019

A Cohort Comparison of Lifespan After Age 100 in Denmark and Sweden: Are Only the Oldest Getting Older?

Demography 2019 04;56(2):665-677

Interdisciplinary Center on Population Dynamics, University of Southern Denmark, Odense, Denmark.

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http://dx.doi.org/10.1007/s13524-018-0755-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6449298PMC
April 2019

Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids.

Authors:
Amy R Bentley Yun J Sung Michael R Brown Thomas W Winkler Aldi T Kraja Ioanna Ntalla Karen Schwander Daniel I Chasman Elise Lim Xuan Deng Xiuqing Guo Jingmin Liu Yingchang Lu Ching-Yu Cheng Xueling Sim Dina Vojinovic Jennifer E Huffman Solomon K Musani Changwei Li Mary F Feitosa Melissa A Richard Raymond Noordam Jenna Baker Guanjie Chen Hugues Aschard Traci M Bartz Jingzhong Ding Rajkumar Dorajoo Alisa K Manning Tuomo Rankinen Albert V Smith Salman M Tajuddin Wei Zhao Mariaelisa Graff Maris Alver Mathilde Boissel Jin Fang Chai Xu Chen Jasmin Divers Evangelos Evangelou Chuan Gao Anuj Goel Yanick Hagemeijer Sarah E Harris Fernando P Hartwig Meian He Andrea R V R Horimoto Fang-Chi Hsu Yi-Jen Hung Anne U Jackson Anuradhani Kasturiratne Pirjo Komulainen Brigitte Kühnel Karin Leander Keng-Hung Lin Jian'an Luan Leo-Pekka Lyytikäinen Nana Matoba Ilja M Nolte Maik Pietzner Bram Prins Muhammad Riaz Antonietta Robino M Abdullah Said Nicole Schupf Robert A Scott Tamar Sofer Alena Stancáková Fumihiko Takeuchi Bamidele O Tayo Peter J van der Most Tibor V Varga Tzung-Dau Wang Yajuan Wang Erin B Ware Wanqing Wen Yong-Bing Xiang Lisa R Yanek Weihua Zhang Jing Hua Zhao Adebowale Adeyemo Saima Afaq Najaf Amin Marzyeh Amini Dan E Arking Zorayr Arzumanyan Tin Aung Christie Ballantyne R Graham Barr Lawrence F Bielak Eric Boerwinkle Erwin P Bottinger Ulrich Broeckel Morris Brown Brian E Cade Archie Campbell Mickaël Canouil Sabanayagam Charumathi Yii-Der Ida Chen Kaare Christensen Maria Pina Concas John M Connell Lisa de Las Fuentes H Janaka de Silva Paul S de Vries Ayo Doumatey Qing Duan Charles B Eaton Ruben N Eppinga Jessica D Faul James S Floyd Nita G Forouhi Terrence Forrester Yechiel Friedlander Ilaria Gandin He Gao Mohsen Ghanbari Sina A Gharib Bruna Gigante Franco Giulianini Hans J Grabe C Charles Gu Tamara B Harris Sami Heikkinen Chew-Kiat Heng Makoto Hirata James E Hixson M Arfan Ikram Yucheng Jia Roby Joehanes Craig Johnson Jost Bruno Jonas Anne E Justice Tomohiro Katsuya Chiea Chuen Khor Tuomas O Kilpeläinen Woon-Puay Koh Ivana Kolcic Charles Kooperberg Jose E Krieger Stephen B Kritchevsky Michiaki Kubo Johanna Kuusisto Timo A Lakka Carl D Langefeld Claudia Langenberg Lenore J Launer Benjamin Lehne Cora E Lewis Yize Li Jingjing Liang Shiow Lin Ching-Ti Liu Jianjun Liu Kiang Liu Marie Loh Kurt K Lohman Tin Louie Anna Luzzi Reedik Mägi Anubha Mahajan Ani W Manichaikul Colin A McKenzie Thomas Meitinger Andres Metspalu Yuri Milaneschi Lili Milani Karen L Mohlke Yukihide Momozawa Andrew P Morris Alison D Murray Mike A Nalls Matthias Nauck Christopher P Nelson Kari E North Jeffrey R O'Connell Nicholette D Palmer George J Papanicolau Nancy L Pedersen Annette Peters Patricia A Peyser Ozren Polasek Neil Poulter Olli T Raitakari Alex P Reiner Frida Renström Treva K Rice Stephen S Rich Jennifer G Robinson Lynda M Rose Frits R Rosendaal Igor Rudan Carsten O Schmidt Pamela J Schreiner William R Scott Peter Sever Yuan Shi Stephen Sidney Mario Sims Jennifer A Smith Harold Snieder John M Starr Konstantin Strauch Heather M Stringham Nicholas Y Q Tan Hua Tang Kent D Taylor Yik Ying Teo Yih Chung Tham Henning Tiemeier Stephen T Turner André G Uitterlinden Diana van Heemst Melanie Waldenberger Heming Wang Lan Wang Lihua Wang Wen Bin Wei Christine A Williams Gregory Wilson Mary K Wojczynski Jie Yao Kristin Young Caizheng Yu Jian-Min Yuan Jie Zhou Alan B Zonderman Diane M Becker Michael Boehnke Donald W Bowden John C Chambers Richard S Cooper Ulf de Faire Ian J Deary Paul Elliott Tõnu Esko Martin Farrall Paul W Franks Barry I Freedman Philippe Froguel Paolo Gasparini Christian Gieger Bernardo L Horta Jyh-Ming Jimmy Juang Yoichiro Kamatani Candace M Kammerer Norihiro Kato Jaspal S Kooner Markku Laakso Cathy C Laurie I-Te Lee Terho Lehtimäki Patrik K E Magnusson Albertine J Oldehinkel Brenda W J H Penninx Alexandre C Pereira Rainer Rauramaa Susan Redline Nilesh J Samani James Scott Xiao-Ou Shu Pim van der Harst Lynne E Wagenknecht Jun-Sing Wang Ya Xing Wang Nicholas J Wareham Hugh Watkins David R Weir Ananda R Wickremasinghe Tangchun Wu Eleftheria Zeggini Wei Zheng Claude Bouchard Michele K Evans Vilmundur Gudnason Sharon L R Kardia Yongmei Liu Bruce M Psaty Paul M Ridker Rob M van Dam Dennis O Mook-Kanamori Myriam Fornage Michael A Province Tanika N Kelly Ervin R Fox Caroline Hayward Cornelia M van Duijn E Shyong Tai Tien Yin Wong Ruth J F Loos Nora Franceschini Jerome I Rotter Xiaofeng Zhu Laura J Bierut W James Gauderman Kenneth Rice Patricia B Munroe Alanna C Morrison Dabeeru C Rao Charles N Rotimi L Adrienne Cupples

Nat Genet 2019 04 29;51(4):636-648. Epub 2019 Mar 29.

Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA.

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http://dx.doi.org/10.1038/s41588-019-0378-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6467258PMC
April 2019

Parallel progress in perceived age and life expectancy.

J Gerontol A Biol Sci Med Sci 2019 Apr 15. Epub 2019 Apr 15.

The Danish Aging Research Center, University of Southern Denmark, Odense, Denmark.

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http://dx.doi.org/10.1093/gerona/glz096DOI Listing
April 2019

Cancer Incidence and Mortality in 260,000 Nordic Twins With 30,000 Prospective Cancers.

Twin Res Hum Genet 2019 04 25;22(2):99-107. Epub 2019 Apr 25.

Department of Social Sciences,University of Tampere,Tampere,Finland.

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http://dx.doi.org/10.1017/thg.2019.10DOI Listing
April 2019

Myeloproliferative Neoplasms in Danish Twins.

Acta Haematol 2018;139(3):195-198. Epub 2018 May 2.

Departments of Clinical Biochemistry and Pharmacology Clinical Genetics, Odense University Hospital, Odense, Denmark.

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http://dx.doi.org/10.1159/000488384DOI Listing
March 2019

Advanced parental age at conception and sex affects mitochondrial DNA copy number in human and fruit flies.

J Gerontol A Biol Sci Med Sci 2019 Mar 15. Epub 2019 Mar 15.

The Danish Aging Research Center and The Danish Twin Registry, Epidemiology and Biostatistics Unit, Institute of Public Health, University of Southern Denmark, Odense, Denmark.

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https://academic.oup.com/biomedgerontology/advance-article/d
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http://dx.doi.org/10.1093/gerona/glz070DOI Listing
March 2019

Hearing loss, cognitive ability, and dementia in men age 19-78 years.

Eur J Epidemiol 2019 Feb 10;34(2):125-130. Epub 2018 Oct 10.

Department of Public Health, University of Copenhagen, Copenhagen, Denmark.

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http://link.springer.com/10.1007/s10654-018-0452-2
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http://dx.doi.org/10.1007/s10654-018-0452-2DOI Listing
February 2019

Independent associations of TOMM40 and APOE variants with body mass index.

Aging Cell 2019 Feb 21;18(1):e12869. Epub 2018 Nov 21.

Biodemography of Aging Research Unit, Social Science Research Institute, Duke University, Durham, North California.

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http://dx.doi.org/10.1111/acel.12869DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6351823PMC
February 2019

DNA methylome profiling of all-cause mortality in comparison with age-associated methylation patterns.

Clin Epigenetics 2019 02 8;11(1):23. Epub 2019 Feb 8.

Epidemiology and Biostatistics, Department of Public Health, Faculty of Health Science, University of Southern Denmark, J. B. Winsløws Vej 9B, DK-5000, Odense, Denmark.

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http://dx.doi.org/10.1186/s13148-019-0622-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6368749PMC
February 2019

Lifespans of Twins: Does Zygosity Matter?

Genes (Basel) 2019 02 20;10(2). Epub 2019 Feb 20.

Department of Epidemiology and Biostatistics, University of Southern Denmark, DK-5000 Odense, Denmark.

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http://dx.doi.org/10.3390/genes10020166DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6409769PMC
February 2019

Age-dependent DNA methylation patterns on the Y chromosome in elderly males.

Aging Cell 2019 Feb 21:e12907. Epub 2019 Feb 21.

Epidemiology and Biostatistics, Department of Public Health, University of Southern Denmark, Odense, Denmark.

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http://doi.wiley.com/10.1111/acel.12907
Publisher Site
http://dx.doi.org/10.1111/acel.12907DOI Listing
February 2019

Declining cancer incidence at the oldest ages: Hallmark of aging or lower diagnostic activity?

J Geriatr Oncol 2019 Feb 20. Epub 2019 Feb 20.

Academy of Geriatric Cancer Research (AgeCare), Odense, Denmark; The Danish Aging Research Center (KC), Department of Epidemiology, Biostatistics and Biodemography, Institute of Public Health, University of Southern Denmark, Odense, Denmark.

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http://dx.doi.org/10.1016/j.jgo.2019.02.001DOI Listing
February 2019

Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries.

Authors:
Mary F Feitosa Aldi T Kraja Daniel I Chasman Yun J Sung Thomas W Winkler Ioanna Ntalla Xiuqing Guo Nora Franceschini Ching-Yu Cheng Xueling Sim Dina Vojinovic Jonathan Marten Solomon K Musani Changwei Li Amy R Bentley Michael R Brown Karen Schwander Melissa A Richard Raymond Noordam Hugues Aschard Traci M Bartz Lawrence F Bielak Rajkumar Dorajoo Virginia Fisher Fernando P Hartwig Andrea R V R Horimoto Kurt K Lohman Alisa K Manning Tuomo Rankinen Albert V Smith Salman M Tajuddin Mary K Wojczynski Maris Alver Mathilde Boissel Qiuyin Cai Archie Campbell Jin Fang Chai Xu Chen Jasmin Divers Chuan Gao Anuj Goel Yanick Hagemeijer Sarah E Harris Meian He Fang-Chi Hsu Anne U Jackson Mika Kähönen Anuradhani Kasturiratne Pirjo Komulainen Brigitte Kühnel Federica Laguzzi Jian'an Luan Nana Matoba Ilja M Nolte Sandosh Padmanabhan Muhammad Riaz Rico Rueedi Antonietta Robino M Abdullah Said Robert A Scott Tamar Sofer Alena Stančáková Fumihiko Takeuchi Bamidele O Tayo Peter J van der Most Tibor V Varga Veronique Vitart Yajuan Wang Erin B Ware Helen R Warren Stefan Weiss Wanqing Wen Lisa R Yanek Weihua Zhang Jing Hua Zhao Saima Afaq Najaf Amin Marzyeh Amini Dan E Arking Tin Aung Eric Boerwinkle Ingrid Borecki Ulrich Broeckel Morris Brown Marco Brumat Gregory L Burke Mickaël Canouil Aravinda Chakravarti Sabanayagam Charumathi Yii-Der Ida Chen John M Connell Adolfo Correa Lisa de Las Fuentes Renée de Mutsert H Janaka de Silva Xuan Deng Jingzhong Ding Qing Duan Charles B Eaton Georg Ehret Ruben N Eppinga Evangelos Evangelou Jessica D Faul Stephan B Felix Nita G Forouhi Terrence Forrester Oscar H Franco Yechiel Friedlander Ilaria Gandin He Gao Mohsen Ghanbari Bruna Gigante C Charles Gu Dongfeng Gu Saskia P Hagenaars Göran Hallmans Tamara B Harris Jiang He Sami Heikkinen Chew-Kiat Heng Makoto Hirata Barbara V Howard M Arfan Ikram Ulrich John Tomohiro Katsuya Chiea Chuen Khor Tuomas O Kilpeläinen Woon-Puay Koh José E Krieger Stephen B Kritchevsky Michiaki Kubo Johanna Kuusisto Timo A Lakka Carl D Langefeld Claudia Langenberg Lenore J Launer Benjamin Lehne Cora E Lewis Yize Li Shiow Lin Jianjun Liu Jingmin Liu Marie Loh Tin Louie Reedik Mägi Colin A McKenzie Thomas Meitinger Andres Metspalu Yuri Milaneschi Lili Milani Karen L Mohlke Yukihide Momozawa Mike A Nalls Christopher P Nelson Nona Sotoodehnia Jill M Norris Jeff R O'Connell Nicholette D Palmer Thomas Perls Nancy L Pedersen Annette Peters Patricia A Peyser Neil Poulter Leslie J Raffel Olli T Raitakari Kathryn Roll Lynda M Rose Frits R Rosendaal Jerome I Rotter Carsten O Schmidt Pamela J Schreiner Nicole Schupf William R Scott Peter S Sever Yuan Shi Stephen Sidney Mario Sims Colleen M Sitlani Jennifer A Smith Harold Snieder John M Starr Konstantin Strauch Heather M Stringham Nicholas Y Q Tan Hua Tang Kent D Taylor Yik Ying Teo Yih Chung Tham Stephen T Turner André G Uitterlinden Peter Vollenweider Melanie Waldenberger Lihua Wang Ya Xing Wang Wen Bin Wei Christine Williams Jie Yao Caizheng Yu Jian-Min Yuan Wei Zhao Alan B Zonderman Diane M Becker Michael Boehnke Donald W Bowden John C Chambers Ian J Deary Tõnu Esko Martin Farrall Paul W Franks Barry I Freedman Philippe Froguel Paolo Gasparini Christian Gieger Jost Bruno Jonas Yoichiro Kamatani Norihiro Kato Jaspal S Kooner Zoltán Kutalik Markku Laakso Cathy C Laurie Karin Leander Terho Lehtimäki Lifelines Cohort Study Patrik K E Magnusson Albertine J Oldehinkel Brenda W J H Penninx Ozren Polasek David J Porteous Rainer Rauramaa Nilesh J Samani James Scott Xiao-Ou Shu Pim van der Harst Lynne E Wagenknecht Nicholas J Wareham Hugh Watkins David R Weir Ananda R Wickremasinghe Tangchun Wu Wei Zheng Claude Bouchard Kaare Christensen Michele K Evans Vilmundur Gudnason Bernardo L Horta Sharon L R Kardia Yongmei Liu Alexandre C Pereira Bruce M Psaty Paul M Ridker Rob M van Dam W James Gauderman Xiaofeng Zhu Dennis O Mook-Kanamori Myriam Fornage Charles N Rotimi L Adrienne Cupples Tanika N Kelly Ervin R Fox Caroline Hayward Cornelia M van Duijn E Shyong Tai Tien Yin Wong Charles Kooperberg Walter Palmas Kenneth Rice Alanna C Morrison Paul Elliott Mark J Caulfield Patricia B Munroe Dabeeru C Rao Michael A Province Daniel Levy

PLoS One 2018 18;13(6):e0198166. Epub 2018 Jun 18.

The Framingham Heart Study, Framingham, Massachusetts, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0198166PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6005576PMC
January 2019

Associations of Mitochondrial and Nuclear Mitochondrial Variants and Genes with Seven Metabolic Traits.

Authors:
Aldi T Kraja Chunyu Liu Jessica L Fetterman Mariaelisa Graff Christian Theil Have Charles Gu Lisa R Yanek Mary F Feitosa Dan E Arking Daniel I Chasman Kristin Young Symen Ligthart W David Hill Stefan Weiss Jian'an Luan Franco Giulianini Ruifang Li-Gao Fernando P Hartwig Shiow J Lin Lihua Wang Tom G Richardson Jie Yao Eliana P Fernandez Mohsen Ghanbari Mary K Wojczynski Wen-Jane Lee Maria Argos Sebastian M Armasu Ruteja A Barve Kathleen A Ryan Ping An Thomas J Baranski Suzette J Bielinski Donald W Bowden Ulrich Broeckel Kaare Christensen Audrey Y Chu Janie Corley Simon R Cox Andre G Uitterlinden Fernando Rivadeneira Cheryl D Cropp E Warwick Daw Diana van Heemst Lisa de Las Fuentes He Gao Ioanna Tzoulaki Tarunveer S Ahluwalia Renée de Mutsert Leslie S Emery A Mesut Erzurumluoglu James A Perry Mao Fu Nita G Forouhi Zhenglong Gu Yang Hai Sarah E Harris Gibran Hemani Steven C Hunt Marguerite R Irvin Anna E Jonsson Anne E Justice Nicola D Kerrison Nicholas B Larson Keng-Hung Lin Latisha D Love-Gregory Rasika A Mathias Joseph H Lee Matthias Nauck Raymond Noordam Ken K Ong James Pankow Amit Patki Alison Pattie Astrid Petersmann Qibin Qi Rasmus Ribel-Madsen Rebecca Rohde Kevin Sandow Theresia M Schnurr Tamar Sofer John M Starr Adele M Taylor Alexander Teumer Nicholas J Timpson Hugoline G de Haan Yujie Wang Peter E Weeke Christine Williams Hongsheng Wu Wei Yang Donglin Zeng Daniel R Witte Bruce S Weir Nicholas J Wareham Henrik Vestergaard Stephen T Turner Christian Torp-Pedersen Evie Stergiakouli Wayne Huey-Herng Sheu Frits R Rosendaal M Arfan Ikram Oscar H Franco Paul M Ridker Thomas T Perls Oluf Pedersen Ellen A Nohr Anne B Newman Allan Linneberg Claudia Langenberg Tuomas O Kilpeläinen Sharon L R Kardia Marit E Jørgensen Torben Jørgensen Thorkild I A Sørensen Georg Homuth Torben Hansen Mark O Goodarzi Ian J Deary Cramer Christensen Yii-Der Ida Chen Aravinda Chakravarti Ivan Brandslund Klaus Bonnelykke Kent D Taylor James G Wilson Santiago Rodriguez Gail Davies Bernardo L Horta Bharat Thyagarajan D C Rao Niels Grarup Victor G Davila-Roman Gavin Hudson Xiuqing Guo Donna K Arnett Caroline Hayward Dhananjay Vaidya Dennis O Mook-Kanamori Hemant K Tiwari Daniel Levy Ruth J F Loos Abbas Dehghan Paul Elliott Afshan N Malik Robert A Scott Diane M Becker Mariza de Andrade Michael A Province James B Meigs Jerome I Rotter Kari E North

Am J Hum Genet 2019 Jan 27;104(1):112-138. Epub 2018 Dec 27.

Department of Epidemiology, University of North Carolina, Chapel Hill, NC 27516, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2018.12.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6323610PMC
January 2019

Diagnosing heart failure in centenarians.

J Geriatr Cardiol 2019 Jan;16(1):1-11

Department of Cardiology, Odense University Hospital, Odense, Denmark.

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http://dx.doi.org/10.11909/j.issn.1671-5411.2019.01.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6379242PMC
January 2019

Comparison of cognitive and physical functioning of Europeans in 2004-05 and 2013.

Int J Epidemiol 2018 10;47(5):1518-1528

Interdisciplinary Center for Research and Education on Population Change, University of Southern Denmark, Odense, Denmark.

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http://dx.doi.org/10.1093/ije/dyy094DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6208267PMC
October 2018

Family occurrence of autoimmune hepatitis: A Danish nationwide registry-based cohort study.

J Hepatol 2018 Oct 7;69(4):873-877. Epub 2018 Jun 7.

Department of Hepatology and Gastroenterology, Aarhus University Hospital, Aarhus, Denmark; Department of Clinical Epidemiology, Aarhus University Hospital, Aarhus, Denmark; Division of Epidemiology and Public Health, School of Medicine, University of Nottingham, Nottingham, United Kingdom.

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http://dx.doi.org/10.1016/j.jhep.2018.05.035DOI Listing
October 2018

Lung function discordance in monozygotic twins and associated differences in blood DNA methylation.

Clin Epigenetics 2017 21;9:132. Epub 2017 Dec 21.

Department of Public Health, Section for Environment Occupation and Health, Danish Ramazzini Centre, Aarhus University, Aarhus, Denmark.

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http://dx.doi.org/10.1186/s13148-017-0427-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5740718PMC
September 2018

Circulating microRNAs disclose biology of normal cognitive function in healthy elderly people - a discovery twin study.

Eur J Hum Genet 2018 09 2;26(9):1378-1387. Epub 2018 May 2.

The Danish Aging Research Center and The Danish Twin Registry, Epidemiology, Biostatistics and Biodemography Unit, Department of Public Health, University of Southern Denmark, 5000, Odense, Denmark.

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http://dx.doi.org/10.1038/s41431-018-0157-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6117263PMC
September 2018

A bidirectional association between cognitive ability in young adulthood and epilepsy: a population-based cohort study.

Int J Epidemiol 2018 08;47(4):1151-1158

Center for Clinical Research and Prevention, Bispebjerg and Frederiksberg Hospitals, Frederiksberg, Denmark.

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http://dx.doi.org/10.1093/ije/dyy018DOI Listing
August 2018

Young adult cognitive ability and subsequent major depression in a cohort of 666,804 Danish men.

J Affect Disord 2018 08 5;235:162-167. Epub 2018 Apr 5.

Center for Clinical Research and Disease Prevention, Bispebjerg and Frederiksberg Hospital, Capital Region, Copenhagen, Denmark; Danish Aging Research Center, Department of Public Health, University of Southern Denmark, Denmark; Department of Public Health, Section of Epidemiology, University of Copenhagen, Øster Farimagsgade 5, Copenhagen K 1014, Denmark.

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http://dx.doi.org/10.1016/j.jad.2018.04.035DOI Listing
August 2018

Irving I. Gottesman's Collaboration in Psychiatric Genetics Research in Denmark.

Twin Res Hum Genet 2018 08;21(4):322-323

Translational Neuropsychiatry Unit,Department of Clinical Medicine,University of Aarhus,Risskov,Denmark.

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http://dx.doi.org/10.1017/thg.2018.32DOI Listing
August 2018

Sex Differences in Genetic Associations With Longevity.

JAMA Netw Open 2018 Aug 24;1(4). Epub 2018 Aug 24.

Center for the Study of Aging and Human Development, Medical School of Duke University, Durham, North Carolina (Zeng, H. Chen); Center for Healthy Aging and Development Studies, National School of Development, Raissun Institute for Advanced Studies, Peking University, Beijing, China (Zeng, Bai); BGI Education Center, University of Chinese Academy of Sciences, Shenzhen, China (Nie);BGI-Shenzhen, Shenzhen, China (Nie, Xiaomin Liu, Ye, Z. Chen, Bolund, Hou, Xiao Liu, Xu, H. Yang); The First Affiliated Hospital, Institute of Translational Medicine, School of Medicine, Zhejiang University, Hangzhou, China (Min, E. Xie); Business School of Xiangtan University, Xiangtan, China (H. Chen); Division of Non-Communicable Disease Control and Community Health, Chinese Center for Disease Control and Prevention, Beijing, China (Yin); National Institute of Environmental Health, Chinese Center for Disease Control and Prevention, Beijing, China (Lv, Shi); Department of Sociology, Peking University, Beijing, China (Lu, Li); School of Life Sciences, Fudan University, Shanghai, China (Ni); Department of Biomedicine, Aarhus University, Aarhus, Denmark (Bolund); Duke Population Research Institute, Duke University, Durham, North Carolina (Land, Yashin, O'Rand); The MOH Key Laboratory of Geriatrics, Beijing Hospital, National Center of Gerontology, Beijing, China (Sun, Z. Yang); School of Life Sciences, Peking University, Beijing, China (Tao, Gu); Boston University, Boston, Massachusetts (Gurinovich, Sebastiani, Perls); University of Bologna, Bologna, Italy (Franceschi); Department of Biostatistics and Bioinformatics, Duke University, Durham, North Carolina (J. Xie); French National Institute on Health and Medical Research and Ecole Pratique des Hautes Etudes, University of Montpellier, Montpellier, France (Robine); Max Planck Institute for Biology of Ageing, Cologne, Germany (Deelen); Department of Molecular Epidemiology, Leiden University Medical Center, Leiden, the Netherlands (Slagboom); Molecular Physiology Institute, Medical Center, Duke University, Durham, North Carolina (Hauser); Department of Neurology, Medical Center, Duke University, Durham, North Carolina (Gottschalk, Lutz); University of Southern Denmark, Odense, Denmark (Tan, Christensen); Human Aging Research Institute and School of Life Science, Nanchang University, Jiangxi, China (Tian); James D. Watson Institute of Genome Sciences, Hangzhou, China (H. Yang); Max Planck Institute for Demographic Research, Rostock, Germany (Vaupel).

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http://dx.doi.org/10.1001/jamanetworkopen.2018.1670DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6173523PMC
August 2018

Improvement in Activities of Daily Living Among Danish Centenarians?-A Comparative Study of Two Centenarian Cohorts Born 20 Years Apart.

J Gerontol A Biol Sci Med Sci 2018 07;73(8):1125-1131

Danish Aging Research Center, Department of Public Health, University of Southern Denmark, Odense, Denmark.

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http://dx.doi.org/10.1093/gerona/glx113DOI Listing
July 2018

Mapping genetic variants for cranial vault shape in humans.

PLoS One 2018 26;13(4):e0196148. Epub 2018 Apr 26.

Center for Craniofacial and Dental Genetics, Department of Oral Biology, University of Pittsburgh, Pittsburgh, PA, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0196148PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919379PMC
July 2018

Whole exome sequencing reveals HSPA1L as a genetic risk factor for spontaneous preterm birth.

PLoS Genet 2018 07 12;14(7):e1007394. Epub 2018 Jul 12.

Division of Human Genetics, Center for Prevention of Preterm Birth, Perinatal Institute, Cincinnati Children's Hospital Medical Center, Department of Pediatrics, University of Cincinnati College of Medicine, March of Dimes Prematurity Research Center Ohio Collaborative, Cincinnati, Ohio, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1007394DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6042692PMC
July 2018

Multiethnic meta-analysis identifies ancestry-specific and cross-ancestry loci for pulmonary function.

Authors:
Annah B Wyss Tamar Sofer Mi Kyeong Lee Natalie Terzikhan Jennifer N Nguyen Lies Lahousse Jeanne C Latourelle Albert Vernon Smith Traci M Bartz Mary F Feitosa Wei Gao Tarunveer S Ahluwalia Wenbo Tang Christopher Oldmeadow Qing Duan Kim de Jong Mary K Wojczynski Xin-Qun Wang Raymond Noordam Fernando Pires Hartwig Victoria E Jackson Tianyuan Wang Ma'en Obeidat Brian D Hobbs Tianxiao Huan Hongsheng Gui Margaret M Parker Donglei Hu Lauren S Mogil Gleb Kichaev Jianping Jin Mariaelisa Graff Tamara B Harris Ravi Kalhan Susan R Heckbert Lavinia Paternoster Kristin M Burkart Yongmei Liu Elizabeth G Holliday James G Wilson Judith M Vonk Jason L Sanders R Graham Barr Renée de Mutsert Ana Maria Baptista Menezes Hieab H H Adams Maarten van den Berge Roby Joehanes Albert M Levin Jennifer Liberto Lenore J Launer Alanna C Morrison Colleen M Sitlani Juan C Celedón Stephen B Kritchevsky Rodney J Scott Kaare Christensen Jerome I Rotter Tobias N Bonten Fernando César Wehrmeister Yohan Bossé Shujie Xiao Sam Oh Nora Franceschini Jennifer A Brody Robert C Kaplan Kurt Lohman Mark McEvoy Michael A Province Frits R Rosendaal Kent D Taylor David C Nickle L Keoki Williams Esteban G Burchard Heather E Wheeler Don D Sin Vilmundur Gudnason Kari E North Myriam Fornage Bruce M Psaty Richard H Myers George O'Connor Torben Hansen Cathy C Laurie Patricia A Cassano Joohon Sung Woo Jin Kim John R Attia Leslie Lange H Marike Boezen Bharat Thyagarajan Stephen S Rich Dennis O Mook-Kanamori Bernardo Lessa Horta André G Uitterlinden Hae Kyung Im Michael H Cho Guy G Brusselle Sina A Gharib Josée Dupuis Ani Manichaikul Stephanie J London

Nat Commun 2018 07 30;9(1):2976. Epub 2018 Jul 30.

Epidemiology Branch National Institute of Environmental Health Sciences, National Institutes of Health, US Department of Health and Human Services, Research Triangle Park, NC, 27709, USA.

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http://dx.doi.org/10.1038/s41467-018-05369-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6065313PMC
July 2018

Does the sex of one's co-twin affect height and BMI in adulthood? A study of dizygotic adult twins from 31 cohorts.

Biol Sex Differ 2017 27;8:14. Epub 2017 Apr 27.

Institute for Molecular Medicine FIMM, University of Helsinki, P.O. Box 20, FI-00014 Helsinki, Finland.

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http://dx.doi.org/10.1186/s13293-017-0134-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5408365PMC
June 2018

Gender differences in the use of anti-infective medications before and after widowhood: a register-based study.

J Epidemiol Community Health 2018 06 19;72(6):526-531. Epub 2018 Feb 19.

Max Planck Institute for Demographic Research, Rostock, Germany.

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http://dx.doi.org/10.1136/jech-2017-210114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5948149PMC
June 2018

The genetic component of human longevity: New insights from the analysis of pathway-based SNP-SNP interactions.

Aging Cell 2018 06 25;17(3):e12755. Epub 2018 Mar 25.

Department of Biology, Ecology and Earth Sciences, University of Calabria, Rende, Italy.

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http://dx.doi.org/10.1111/acel.12755DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946073PMC
June 2018

Soft tissue nasal asymmetry as an indicator of orofacial cleft predisposition.

Am J Med Genet A 2018 06 16;176(6):1296-1303. Epub 2018 Apr 16.

Center for Craniofacial and Dental Genetics, Department of Oral Biology, University of Pittsburgh, Pittsburgh, Pennsylvania.

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http://dx.doi.org/10.1002/ajmg.a.38688DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992056PMC
June 2018

Risk of epilepsy in opposite-sex and same-sex twins: a twin cohort study.

Biol Sex Differ 2018 06 4;9(1):21. Epub 2018 Jun 4.

Department of Clinical Epidemiology, Institute for Clinical Medicine, Aarhus University Hospital, Olof Palmes Allé 43-45, DK-8200, Aarhus N, Denmark.

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http://dx.doi.org/10.1186/s13293-018-0179-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5987428PMC
June 2018

Is Who you Ask Important? Concordance Between Survey and Registry Data on Medication Use Among Self- and Proxy-Respondents in the Longitudinal Study of Aging Danish Twins and the Danish 1905-Cohort Study.

J Gerontol A Biol Sci Med Sci 2018 Jun 19. Epub 2018 Jun 19.

Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institute and Stockholm University, Sweden.

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http://dx.doi.org/10.1093/gerona/gly104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6477639PMC
June 2018

Lack of Association Between Proton Pump Inhibitor Use and Cognitive Decline.

Clin Gastroenterol Hepatol 2018 May 31;16(5):681-689. Epub 2018 Jan 31.

Department of Neurology, Odense University Hospital and Department of Clinical Medicine, Faculty of Health Sciences, University of Southern Denmark, Odense, Denmark. Electronic address:

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http://dx.doi.org/10.1016/j.cgh.2018.01.034DOI Listing
May 2018

Reply to Delanghe et al.: Iron status is not likely to play a key role in the gender survival gap under extreme conditions.

Proc Natl Acad Sci U S A 2018 05 17;115(18):E4150. Epub 2018 Apr 17.

Biodemographic Unit, Department of Public Health, University of Southern Denmark, DK-5000 Odense, Denmark;

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http://dx.doi.org/10.1073/pnas.1801481115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5939110PMC
May 2018

Heritability of Schizophrenia and Schizophrenia Spectrum Based on the Nationwide Danish Twin Register.

Biol Psychiatry 2018 03 1;83(6):492-498. Epub 2017 Sep 1.

CINS-Lundbeck Foundation Center of Excellence for Clinical Intervention and Neuropsychiatric Schizophrenia Research, Glostrup, Denmark; CNSR-Center for Neuropsychiatric Schizophrenia Research, Mental Health Centre Glostrup, Mental Health Services, Capital Region of Denmark, Glostrup, Denmark; Faculty of Health and Medical Sciences, Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.

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http://dx.doi.org/10.1016/j.biopsych.2017.08.017DOI Listing
March 2018

A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure.

Authors:
Yun J Sung Thomas W Winkler Lisa de Las Fuentes Amy R Bentley Michael R Brown Aldi T Kraja Karen Schwander Ioanna Ntalla Xiuqing Guo Nora Franceschini Yingchang Lu Ching-Yu Cheng Xueling Sim Dina Vojinovic Jonathan Marten Solomon K Musani Changwei Li Mary F Feitosa Tuomas O Kilpeläinen Melissa A Richard Raymond Noordam Stella Aslibekyan Hugues Aschard Traci M Bartz Rajkumar Dorajoo Yongmei Liu Alisa K Manning Tuomo Rankinen Albert Vernon Smith Salman M Tajuddin Bamidele O Tayo Helen R Warren Wei Zhao Yanhua Zhou Nana Matoba Tamar Sofer Maris Alver Marzyeh Amini Mathilde Boissel Jin Fang Chai Xu Chen Jasmin Divers Ilaria Gandin Chuan Gao Franco Giulianini Anuj Goel Sarah E Harris Fernando Pires Hartwig Andrea R V R Horimoto Fang-Chi Hsu Anne U Jackson Mika Kähönen Anuradhani Kasturiratne Brigitte Kühnel Karin Leander Wen-Jane Lee Keng-Hung Lin Jian 'an Luan Colin A McKenzie He Meian Christopher P Nelson Rainer Rauramaa Nicole Schupf Robert A Scott Wayne H H Sheu Alena Stančáková Fumihiko Takeuchi Peter J van der Most Tibor V Varga Heming Wang Yajuan Wang Erin B Ware Stefan Weiss Wanqing Wen Lisa R Yanek Weihua Zhang Jing Hua Zhao Saima Afaq Tamuno Alfred Najaf Amin Dan Arking Tin Aung R Graham Barr Lawrence F Bielak Eric Boerwinkle Erwin P Bottinger Peter S Braund Jennifer A Brody Ulrich Broeckel Claudia P Cabrera Brian Cade Yu Caizheng Archie Campbell Mickaël Canouil Aravinda Chakravarti Ganesh Chauhan Kaare Christensen Massimiliano Cocca Francis S Collins John M Connell Renée de Mutsert H Janaka de Silva Stephanie Debette Marcus Dörr Qing Duan Charles B Eaton Georg Ehret Evangelos Evangelou Jessica D Faul Virginia A Fisher Nita G Forouhi Oscar H Franco Yechiel Friedlander He Gao Bruna Gigante Misa Graff C Charles Gu Dongfeng Gu Preeti Gupta Saskia P Hagenaars Tamara B Harris Jiang He Sami Heikkinen Chew-Kiat Heng Makoto Hirata Albert Hofman Barbara V Howard Steven Hunt Marguerite R Irvin Yucheng Jia Roby Joehanes Anne E Justice Tomohiro Katsuya Joel Kaufman Nicola D Kerrison Chiea Chuen Khor Woon-Puay Koh Heikki A Koistinen Pirjo Komulainen Charles Kooperberg Jose E Krieger Michiaki Kubo Johanna Kuusisto Carl D Langefeld Claudia Langenberg Lenore J Launer Benjamin Lehne Cora E Lewis Yize Li Sing Hui Lim Shiow Lin Ching-Ti Liu Jianjun Liu Jingmin Liu Kiang Liu Yeheng Liu Marie Loh Kurt K Lohman Jirong Long Tin Louie Reedik Mägi Anubha Mahajan Thomas Meitinger Andres Metspalu Lili Milani Yukihide Momozawa Andrew P Morris Thomas H Mosley Peter Munson Alison D Murray Mike A Nalls Ubaydah Nasri Jill M Norris Kari North Adesola Ogunniyi Sandosh Padmanabhan Walter R Palmas Nicholette D Palmer James S Pankow Nancy L Pedersen Annette Peters Patricia A Peyser Ozren Polasek Olli T Raitakari Frida Renström Treva K Rice Paul M Ridker Antonietta Robino Jennifer G Robinson Lynda M Rose Igor Rudan Charumathi Sabanayagam Babatunde L Salako Kevin Sandow Carsten O Schmidt Pamela J Schreiner William R Scott Sudha Seshadri Peter Sever Colleen M Sitlani Jennifer A Smith Harold Snieder John M Starr Konstantin Strauch Hua Tang Kent D Taylor Yik Ying Teo Yih Chung Tham André G Uitterlinden Melanie Waldenberger Lihua Wang Ya X Wang Wen Bin Wei Christine Williams Gregory Wilson Mary K Wojczynski Jie Yao Jian-Min Yuan Alan B Zonderman Diane M Becker Michael Boehnke Donald W Bowden John C Chambers Yii-Der Ida Chen Ulf de Faire Ian J Deary Tõnu Esko Martin Farrall Terrence Forrester Paul W Franks Barry I Freedman Philippe Froguel Paolo Gasparini Christian Gieger Bernardo Lessa Horta Yi-Jen Hung Jost B Jonas Norihiro Kato Jaspal S Kooner Markku Laakso Terho Lehtimäki Kae-Woei Liang Patrik K E Magnusson Anne B Newman Albertine J Oldehinkel Alexandre C Pereira Susan Redline Rainer Rettig Nilesh J Samani James Scott Xiao-Ou Shu Pim van der Harst Lynne E Wagenknecht Nicholas J Wareham Hugh Watkins David R Weir Ananda R Wickremasinghe Tangchun Wu Wei Zheng Yoichiro Kamatani Cathy C Laurie Claude Bouchard Richard S Cooper Michele K Evans Vilmundur Gudnason Sharon L R Kardia Stephen B Kritchevsky Daniel Levy Jeff R O'Connell Bruce M Psaty Rob M van Dam Mario Sims Donna K Arnett Dennis O Mook-Kanamori Tanika N Kelly Ervin R Fox Caroline Hayward Myriam Fornage Charles N Rotimi Michael A Province Cornelia M van Duijn E Shyong Tai Tien Yin Wong Ruth J F Loos Alex P Reiner Jerome I Rotter Xiaofeng Zhu Laura J Bierut W James Gauderman Mark J Caulfield Paul Elliott Kenneth Rice Patricia B Munroe Alanna C Morrison L Adrienne Cupples Dabeeru C Rao Daniel I Chasman

Am J Hum Genet 2018 03 15;102(3):375-400. Epub 2018 Feb 15.

Division of Preventive Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA 02215, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2018.01.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5985266PMC
March 2018

Resting Heart Rate Is Not Associated with Cognitive Function.

Neuroepidemiology 2018 22;50(3-4):160-167. Epub 2018 Mar 22.

The Unit of Epidemiology, Biostatistics and Biodemography, The Danish Twin Registry, The Danish Aging Research Center, Odense, Denmark.

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http://dx.doi.org/10.1159/000487802DOI Listing
March 2018

Longitudinal Twin Study of Subjective Health: Differences in Genetic and Environmental Components of Variance Across Age and Sex.

J Gerontol B Psychol Sci Soc Sci 2018 Mar 24. Epub 2018 Mar 24.

Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1093/geronb/gby030DOI Listing
March 2018

Genetic and environmental influences on cardiovascular risk factors and cognitive function: A Chinese twin aging study.

Geriatr Gerontol Int 2018 Feb 30;18(2):352-359. Epub 2017 Aug 30.

Unit of Human Genetics, Department of Clinical Research, University of Southern Denmark, Odense, Denmark.

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http://dx.doi.org/10.1111/ggi.13161DOI Listing
February 2018

No impact of surgery on cognitive function: a longitudinal study of middle-aged Danish twins.

Ann Epidemiol 2018 02 19;28(2):95-101.e1. Epub 2017 Dec 19.

The Unit of Epidemiology, Biostatistics and Biodemography, Danish Twin Registry, Danish Aging Research Center, Department of Public Health, University of Southern Denmark, Odense C, Denmark; Max-Planck Odense Center on the Biodemography of Aging, University of Southern Denmark, Odense C, Denmark; Clinical Genetics, Odense University Hospital, Odense C, Denmark; Clinical Biochemistry and Pharmacology, Odense University Hospital, Odense C, Denmark.

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https://linkinghub.elsevier.com/retrieve/pii/S10472797173063
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http://dx.doi.org/10.1016/j.annepidem.2017.12.004DOI Listing
February 2018

DNA Methylation and All-Cause Mortality in Middle-Aged and Elderly Danish Twins.

Genes (Basel) 2018 Feb 8;9(2). Epub 2018 Feb 8.

Epidemiology and Biostatistics, Department of Public Health, University of Southern Denmark, 5000 Odense, Denmark.

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http://dx.doi.org/10.3390/genes9020078DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5852574PMC
February 2018

Heritability of resting heart rate and association with mortality in middle-aged and elderly twins.

Heart 2018 01 21;104(1):30-36. Epub 2017 Jun 21.

The Danish Twin Registry, Department of Public Health, University of Southern Denmark, Odense, Denmark.

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http://dx.doi.org/10.1136/heartjnl-2016-310986DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5831408PMC
January 2018

DNA methylation age and perceived age in elderly Danish twins.

Mech Ageing Dev 2018 01 28;169:40-44. Epub 2017 Sep 28.

Epidemiology, Biostatistics and Biodemography, Department of Public Health, University of Southern Denmark, Odense, Denmark; The Danish Twin Registry and the Danish Aging Research Center, Department of Public Health, University of Southern Denmark, Odense, Denmark.

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http://dx.doi.org/10.1016/j.mad.2017.09.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6190692PMC
January 2018

Women live longer than men even during severe famines and epidemics.

Proc Natl Acad Sci U S A 2018 01 8;115(4):E832-E840. Epub 2018 Jan 8.

Max Planck Odense Center on the Biodemography of Aging, University of Southern Denmark, DK-5230 Odense, Denmark;

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http://dx.doi.org/10.1073/pnas.1701535115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5789901PMC
January 2018

Cognitive ability in young adulthood and risk of dementia in a cohort of Danish men, brothers, and twins.

Alzheimers Dement 2017 Dec 19;13(12):1355-1363. Epub 2017 May 19.

Department of Public Health, Danish Aging Research Center, University of Southern Denmark, Odense, Denmark; Department of Clinical Genetics, Odense University Hospital, Odense, Denmark; Department of Clinical Biochemistry and Pharmacology, Odense University Hospital, Odense, Denmark.

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http://dx.doi.org/10.1016/j.jalz.2017.04.003DOI Listing
December 2017

Epigenome-Wide Association Study of Cognitive Functioning in Middle-Aged Monozygotic Twins.

Front Aging Neurosci 2017 12;9:413. Epub 2017 Dec 12.

The Danish Twin Registry, Institute of Public Health, University of Southern Denmark, Odense, Denmark.

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http://dx.doi.org/10.3389/fnagi.2017.00413DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5733014PMC
December 2017

Testing the face shape hypothesis in twins discordant for nonsyndromic orofacial clefting.

Am J Med Genet A 2017 Nov 8;173(11):2886-2892. Epub 2017 Sep 8.

Center for Craniofacial and Dental Genetics, Department of Oral Biology, University of Pittsburgh, Pittsburgh, Pennsylvania.

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http://dx.doi.org/10.1002/ajmg.a.38471DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5725745PMC
November 2017

Handling blood cell composition in epigenetic studies on ageing.

Int J Epidemiol 2017 10;46(5):1717-1718

Department of Public Health.

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http://dx.doi.org/10.1093/ije/dyx083DOI Listing
October 2017

CNV-association meta-analysis in 191,161 European adults reveals new loci associated with anthropometric traits.

Authors:
Aurélien Macé Marcus A Tuke Patrick Deelen Kati Kristiansson Hannele Mattsson Margit Nõukas Yadav Sapkota Ursula Schick Eleonora Porcu Sina Rüeger Aaron F McDaid David Porteous Thomas W Winkler Erika Salvi Nick Shrine Xueping Liu Wei Q Ang Weihua Zhang Mary F Feitosa Cristina Venturini Peter J van der Most Anders Rosengren Andrew R Wood Robin N Beaumont Samuel E Jones Katherine S Ruth Hanieh Yaghootkar Jessica Tyrrell Aki S Havulinna Harmen Boers Reedik Mägi Jennifer Kriebel Martina Müller-Nurasyid Markus Perola Markku Nieminen Marja-Liisa Lokki Mika Kähönen Jorma S Viikari Frank Geller Jari Lahti Aarno Palotie Päivikki Koponen Annamari Lundqvist Harri Rissanen Erwin P Bottinger Saima Afaq Mary K Wojczynski Petra Lenzini Ilja M Nolte Thomas Sparsø Nicole Schupf Kaare Christensen Thomas T Perls Anne B Newman Thomas Werge Harold Snieder Timothy D Spector John C Chambers Seppo Koskinen Mads Melbye Olli T Raitakari Terho Lehtimäki Martin D Tobin Louise V Wain Juha Sinisalo Annette Peters Thomas Meitinger Nicholas G Martin Naomi R Wray Grant W Montgomery Sarah E Medland Morris A Swertz Erkki Vartiainen Katja Borodulin Satu Männistö Anna Murray Murielle Bochud Sébastien Jacquemont Fernando Rivadeneira Thomas F Hansen Albertine J Oldehinkel Massimo Mangino Michael A Province Panos Deloukas Jaspal S Kooner Rachel M Freathy Craig Pennell Bjarke Feenstra David P Strachan Guillaume Lettre Joel Hirschhorn Daniele Cusi Iris M Heid Caroline Hayward Katrin Männik Jacques S Beckmann Ruth J F Loos Dale R Nyholt Andres Metspalu Johan G Eriksson Michael N Weedon Veikko Salomaa Lude Franke Alexandre Reymond Timothy M Frayling Zoltán Kutalik

Nat Commun 2017 09 29;8(1):744. Epub 2017 Sep 29.

Institute of Social and Preventive Medicine, Lausanne University Hospital, Lausanne, 1010, Switzerland.

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http://dx.doi.org/10.1038/s41467-017-00556-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5622064PMC
September 2017

Differences in genetic and environmental variation in adult BMI by sex, age, time period, and region: an individual-based pooled analysis of 40 twin cohorts.

Authors:
Karri Silventoinen Aline Jelenkovic Reijo Sund Yoshie Yokoyama Yoon-Mi Hur Wendy Cozen Amie E Hwang Thomas M Mack Chika Honda Fujio Inui Yoshinori Iwatani Mikio Watanabe Rie Tomizawa Kirsi H Pietiläinen Aila Rissanen Sisira H Siribaddana Matthew Hotopf Athula Sumathipala Fruhling Rijsdijk Qihua Tan Dongfeng Zhang Zengchang Pang Maarit Piirtola Sari Aaltonen Sevgi Y Öncel Fazil Aliev Esther Rebato Jacob B Hjelmborg Kaare Christensen Axel Skytthe Kirsten O Kyvik Judy L Silberg Lindon J Eaves Tessa L Cutler Juan R Ordoñana Juan F Sánchez-Romera Lucia Colodro-Conde Yun-Mi Song Sarah Yang Kayoung Lee Carol E Franz William S Kremen Michael J Lyons Andreas Busjahn Tracy L Nelson Keith E Whitfield Christian Kandler Kerry L Jang Margaret Gatz David A Butler Maria A Stazi Corrado Fagnani Cristina D'Ippolito Glen E Duncan Dedra Buchwald Nicholas G Martin Sarah E Medland Grant W Montgomery Hoe-Uk Jeong Gary E Swan Ruth Krasnow Patrik Ke Magnusson Nancy L Pedersen Anna K Dahl Aslan Tom A McAdams Thalia C Eley Alice M Gregory Per Tynelius Laura A Baker Catherine Tuvblad Gombojav Bayasgalan Danshiitsoodol Narandalai Timothy D Spector Massimo Mangino Genevieve Lachance S Alexandra Burt Kelly L Klump Jennifer R Harris Ingunn Brandt Thomas S Nilsen Robert F Krueger Matt McGue Shandell Pahlen Robin P Corley Brooke M Huibregtse Meike Bartels Catharina Em van Beijsterveldt Gonneke Willemsen Jack H Goldberg Finn Rasmussen Adam D Tarnoki David L Tarnoki Catherine A Derom Robert F Vlietinck Ruth Jf Loos John L Hopper Joohon Sung Hermine H Maes Eric Turkheimer Dorret I Boomsma Thorkild Ia Sørensen Jaakko Kaprio

Am J Clin Nutr 2017 Aug 5;106(2):457-466. Epub 2017 Jul 5.

Public Health, and.

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http://dx.doi.org/10.3945/ajcn.117.153643DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5525120PMC
August 2017

Identification, replication and characterization of epigenetic remodelling in the aging genome: a cross population analysis.

Sci Rep 2017 08 15;7(1):8183. Epub 2017 Aug 15.

Department of Clinical Research, Unit of Human Genetics, University of Southern Denmark, Odense, Denmark.

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http://dx.doi.org/10.1038/s41598-017-08346-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5557932PMC
August 2017

The oldest-old in China - Authors' reply.

Lancet 2017 08;390(10097):847

Max Planck Institute for Demographic Research, Rostock, Germany.

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http://dx.doi.org/10.1016/S0140-6736(17)31829-9DOI Listing
August 2017

Use of Psychotropic Medications and Visits to Psychiatrists and Psychologists among Individuals with Nonsyndromic Oral Clefts: A Population-Based Cohort Study.

Birth Defects Res 2017 Jul 12;109(11):824-835. Epub 2017 Apr 12.

Epidemiology, Biostatistics and Biodemography, Department of Public Health, University of Southern Denmark, Odense C, Denmark.

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http://dx.doi.org/10.1002/bdr2.1024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5568049PMC
July 2017

Twin-singleton early-life survival in sub-Saharan Africa.

Lancet Glob Health 2017 07 31;5(7):e636-e637. Epub 2017 May 31.

Bandim Health Project, INDEPTH Network, Apartado 861, 1004 Bissau Codex, Guinea-Bissau; Research Center for Vitamins and Vaccines, Statens Serum Institute, Copenhagen, Denmark; Department of Endocrinology, Odense University Hospital, Odense, Denmark.

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http://dx.doi.org/10.1016/S2214-109X(17)30223-1DOI Listing
July 2017

Chromosomal Aberrations in Monozygotic and Dizygotic Twins Versus Singletons in Denmark During 1968-2009.

Twin Res Hum Genet 2017 06 9;20(3):216-225. Epub 2017 May 9.

Department of Clinical Genetics,Odense University Hospital,Odense C,Denmark.

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http://dx.doi.org/10.1017/thg.2017.17DOI Listing
June 2017

Comparison of Late Mortality Among Twins Versus Singletons With Congenital Heart Defects.

Am J Cardiol 2017 05 1;119(10):1680-1686. Epub 2017 Mar 1.

The Danish Twin Registry, University of Southern Denmark, Odense, Denmark. Electronic address:

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http://dx.doi.org/10.1016/j.amjcard.2017.02.006DOI Listing
May 2017

Is an Early Age at Illness Onset in Schizophrenia Associated With Increased Genetic Susceptibility? Analysis of Data From the Nationwide Danish Twin Register.

EBioMedicine 2017 Apr 6;18:320-326. Epub 2017 Apr 6.

Lundbeck Foundation Center for Clinical Intervention and Neuropsychiatric Schizophrenia Research (CINS), Denmark; Center for Neuropsychiatric Schizophrenia Research, Mental Health Center Glostrup, Mental Health Services, Capital Region of Denmark, University of Copenhagen, DK-2600, Glostrup, Denmark; Faculty of Health and Medical Sciences, Department of Clinical Medicine, University of Copenhagen, Denmark.

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http://dx.doi.org/10.1016/j.ebiom.2017.04.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5405190PMC
April 2017