Publications by authors named "Kaare Christensen"

100Publications

Differential long noncoding RNA profiling of BMI in twins.

Epigenomics 2020 Sep 9;12(17):1531-1541. Epub 2020 Sep 9.

Unit of Epidemiology, Biostatistics & Biodemography, Department of Public Health, University of Southern Denmark, Odense, Denmark.

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http://dx.doi.org/10.2217/epi-2020-0033DOI Listing
September 2020

Mechanisms underlying familial aggregation of exceptional health and survival: A three-generation cohort study.

Aging Cell 2020 Oct 4;19(10):e13228. Epub 2020 Sep 4.

Department of Genetics, Washington University School of Medicine, St. Louis, MO, USA.

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http://dx.doi.org/10.1111/acel.13228DOI Listing
October 2020

Familial risk and heritability of ischemic heart disease and stroke in Danish twins.

Scand J Public Health 2020 Sep 3:1403494820953322. Epub 2020 Sep 3.

Center for Clinical Research and Prevention, Bispebjerg and Frederiksberg Hospital, Denmark.

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http://dx.doi.org/10.1177/1403494820953322DOI Listing
September 2020

Circulating Procollagen type III N-terminal peptide (P3NP) and Physical Function in Adults from The Long Life Family Study.

J Gerontol A Biol Sci Med Sci 2020 Aug 14. Epub 2020 Aug 14.

University of Pittsburgh, Graduate School of Public Health, Department of Epidemiology.

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http://dx.doi.org/10.1093/gerona/glaa197DOI Listing
August 2020

Physical robustness and resilience among long-lived female siblings: a comparison with sporadic long-livers.

Aging (Albany NY) 2020 07 11;12(14):15157-15168. Epub 2020 Jul 11.

Epidemiology, Biostatistics, and Biodemography, Department of Public Health, University of Southern Denmark, Odense, Denmark.

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http://dx.doi.org/10.18632/aging.103618DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7425496PMC
July 2020

Heritability of subfertility among Danish twins.

Fertil Steril 2020 Sep 2;114(3):618-627. Epub 2020 Jul 2.

Unit of Epidemiology, Biostatistics and Biodemography, Department of Public Health, University of Southern Denmark, Odense, Denmark; Interdisciplinary Centre on Population Dynamics (CPop), University of Southern Denmark, Odense, Denmark.

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http://dx.doi.org/10.1016/j.fertnstert.2020.03.014DOI Listing
September 2020

Apolipoprotein E ε4 and cognitive function after surgery in middle-aged and elderly Danish twins.

Eur J Anaesthesiol 2020 11;37(11):984-991

From the The Unit of Epidemiology, Biostatistics and Biodemography, Department of Public Health, Danish Twin Registry, Danish Aging Research Center, University of Southern Denmark (UD, MW, MT, KC, JM-F), Department of Anaesthesiology and Intensive Care Medicine, Odense University Hospital, Odense (TGH), Department of Anaesthesia, Centre of Head and Orthopaedics, Rigshospitalet, University of Copenhagen, Copenhagen (LSR), Clinical Biochemistry and Pharmacology (KC) and Clinical Genetics, Odense University Hospital, Odense, Denmark (KC, JM-F).

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http://dx.doi.org/10.1097/EJA.0000000000001250DOI Listing
November 2020

Patterns of multi-domain cognitive aging in participants of the Long Life Family Study.

Geroscience 2020 Oct 8;42(5):1335-1350. Epub 2020 Jun 8.

Department of Medicine, Geriatrics Section, Boston University School of Medicine, Robinson 2400, 72 E Concord St, Boston, MA, 02118, USA.

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http://dx.doi.org/10.1007/s11357-020-00202-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7525612PMC
October 2020

Is Religiousness Associated with Better Lifestyle and Health Among Danes? Findings from SHARE.

J Relig Health 2020 Jun 2. Epub 2020 Jun 2.

Research Unit of Epidemiology, Biostatistics and Biodemography, Department of Public Health, University of Southern Denmark, J. B. Winsløws Vej 9B, 5000, Odense, Denmark.

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http://dx.doi.org/10.1007/s10943-020-01050-3DOI Listing
June 2020

Age-specific cancer rates: a bird's-eye view on progress.

Ann Epidemiol 2020 08 6;48:51-54.e1. Epub 2020 May 6.

Unit of Epidemiology, Biostatistics and Biodemography, Department of Public Health, University of Southern Denmark, Odense, Denmark; Interdisciplinary Centre on Population Dynamics, University of Southern Denmark, Odense, Denmark.

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http://dx.doi.org/10.1016/j.annepidem.2020.04.007DOI Listing
August 2020

Rethinking morbidity compression.

Eur J Epidemiol 2020 May 16;35(5):381-388. Epub 2020 May 16.

Department of Epidemiology, Biostatistics, and Biodemography, University of Southern Denmark, Odense, Denmark.

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http://dx.doi.org/10.1007/s10654-020-00642-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7250949PMC
May 2020

Gene-educational attainment interactions in a multi-ancestry genome-wide meta-analysis identify novel blood pressure loci.

Authors:
Lisa de Las Fuentes Yun Ju Sung Raymond Noordam Thomas Winkler Mary F Feitosa Karen Schwander Amy R Bentley Michael R Brown Xiuqing Guo Alisa Manning Daniel I Chasman Hugues Aschard Traci M Bartz Lawrence F Bielak Archie Campbell Ching-Yu Cheng Rajkumar Dorajoo Fernando P Hartwig A R V R Horimoto Changwei Li Ruifang Li-Gao Yongmei Liu Jonathan Marten Solomon K Musani Ioanna Ntalla Tuomo Rankinen Melissa Richard Xueling Sim Albert V Smith Salman M Tajuddin Bamidele O Tayo Dina Vojinovic Helen R Warren Deng Xuan Maris Alver Mathilde Boissel Jin-Fang Chai Xu Chen Kaare Christensen Jasmin Divers Evangelos Evangelou Chuan Gao Giorgia Girotto Sarah E Harris Meian He Fang-Chi Hsu Brigitte Kühnel Federica Laguzzi Xiaoyin Li Leo-Pekka Lyytikäinen Ilja M Nolte Alaitz Poveda Rainer Rauramaa Muhammad Riaz Rico Rueedi Xiao-Ou Shu Harold Snieder Tamar Sofer Fumihiko Takeuchi Niek Verweij Erin B Ware Stefan Weiss Lisa R Yanek Najaf Amin Dan E Arking Donna K Arnett Sven Bergmann Eric Boerwinkle Jennifer A Brody Ulrich Broeckel Marco Brumat Gregory Burke Claudia P Cabrera Mickaël Canouil Miao Li Chee Yii-Der Ida Chen Massimiliano Cocca John Connell H Janaka de Silva Paul S de Vries Gudny Eiriksdottir Jessica D Faul Virginia Fisher Terrence Forrester Ervin F Fox Yechiel Friedlander He Gao Bruna Gigante Franco Giulianini Chi Charles Gu Dongfeng Gu Tamara B Harris Jiang He Sami Heikkinen Chew-Kiat Heng Steven Hunt M Arfan Ikram Marguerite R Irvin Mika Kähönen Maryam Kavousi Chiea Chuen Khor Tuomas O Kilpeläinen Woon-Puay Koh Pirjo Komulainen Aldi T Kraja J E Krieger Carl D Langefeld Yize Li Jingjing Liang David C M Liewald Ching-Ti Liu Jianjun Liu Kurt K Lohman Reedik Mägi Colin A McKenzie Thomas Meitinger Andres Metspalu Yuri Milaneschi Lili Milani Dennis O Mook-Kanamori Mike A Nalls Christopher P Nelson Jill M Norris Jeff O'Connell Adesola Ogunniyi Sandosh Padmanabhan Nicholette D Palmer Nancy L Pedersen Thomas Perls Annette Peters Astrid Petersmann Patricia A Peyser Ozren Polasek David J Porteous Leslie J Raffel Treva K Rice Jerome I Rotter Igor Rudan Oscar-Leonel Rueda-Ochoa Charumathi Sabanayagam Babatunde L Salako Pamela J Schreiner James M Shikany Stephen S Sidney Mario Sims Colleen M Sitlani Jennifer A Smith John M Starr Konstantin Strauch Morris A Swertz Alexander Teumer Yih Chung Tham André G Uitterlinden Dhananjay Vaidya M Yldau van der Ende Melanie Waldenberger Lihua Wang Ya-Xing Wang Wen-Bin Wei David R Weir Wanqing Wen Jie Yao Bing Yu Caizheng Yu Jian-Min Yuan Wei Zhao Alan B Zonderman Diane M Becker Donald W Bowden Ian J Deary Marcus Dörr Tõnu Esko Barry I Freedman Philippe Froguel Paolo Gasparini Christian Gieger Jost Bruno Jonas Candace M Kammerer Norihiro Kato Timo A Lakka Karin Leander Terho Lehtimäki Patrik K E Magnusson Pedro Marques-Vidal Brenda W J H Penninx Nilesh J Samani Pim van der Harst Lynne E Wagenknecht Tangchun Wu Wei Zheng Xiaofeng Zhu Claude Bouchard Richard S Cooper Adolfo Correa Michele K Evans Vilmundur Gudnason Caroline Hayward Bernardo L Horta Tanika N Kelly Stephen B Kritchevsky Daniel Levy Walter R Palmas A C Pereira Michael M Province Bruce M Psaty Paul M Ridker Charles N Rotimi E Shyong Tai Rob M van Dam Cornelia M van Duijn Tien Yin Wong Kenneth Rice W James Gauderman Alanna C Morrison Kari E North Sharon L R Kardia Mark J Caulfield Paul Elliott Patricia B Munroe Paul W Franks Dabeeru C Rao Myriam Fornage

Mol Psychiatry 2020 May 5. Epub 2020 May 5.

Institute of Molecular Medicine, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, TX, 70808, USA.

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http://dx.doi.org/10.1038/s41380-020-0719-3DOI Listing
May 2020

Exploratory analysis of age and sex dependent DNA methylation patterns on the X-chromosome in whole blood samples.

Genome Med 2020 04 28;12(1):39. Epub 2020 Apr 28.

Epidemiology and Biostatistics, Department of Public Health, Faculty of Health Science, University of Southern Denmark, J. B. Winsløws Vej 9B, DK-5000, Odense C, Denmark.

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http://dx.doi.org/10.1186/s13073-020-00736-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7189689PMC
April 2020

Use of prescription medication in the last years of life: a population-based comparison of two oldest old Danish birth cohorts born 10 years apart.

Age Ageing 2020 Apr 21. Epub 2020 Apr 21.

Epidemiology, Biostatistics and Biodemography, Department of Public Health, University of Southern Denmark, Odense, Denmark.

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http://dx.doi.org/10.1093/ageing/afaa064DOI Listing
April 2020

Weighted gene co-regulation network analysis (WGCNA) of promoter DNA methylation on all-cause mortality in old-aged birth cohorts finds modules of high-risk associated biomarkers.

J Gerontol A Biol Sci Med Sci 2020 Mar 10. Epub 2020 Mar 10.

Epidemiology and Biostatistics, Department of Public Health, University of Southern Denmark, Odense, Denmark.

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http://dx.doi.org/10.1093/gerona/glaa066DOI Listing
March 2020

Gene discovery for high-density lipoprotein cholesterol level change over time in prospective family studies.

Atherosclerosis 2020 03 14;297:102-110. Epub 2020 Feb 14.

Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St Louis, MO, USA.

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http://dx.doi.org/10.1016/j.atherosclerosis.2020.02.005DOI Listing
March 2020

The twin representativeness assumption.

Neurosci Biobehav Rev 2020 05 20;112:374-375. Epub 2020 Feb 20.

The Danish Twin Registry, Department of Public Health, University of Southern Denmark, Odense, Denmark; Department of Psychology, University of Minnesota, Minneapolis, MN, USA.

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http://dx.doi.org/10.1016/j.neubiorev.2020.02.026DOI Listing
May 2020

Body height in young adult men and risk of dementia later in adult life.

Elife 2020 Feb 11;9. Epub 2020 Feb 11.

Center for Clinical Research and Prevention, Bispebjerg and Frederiksberg Hospital, Copenhagen, Denmark.

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http://dx.doi.org/10.7554/eLife.51168DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7012597PMC
February 2020

β-adrenoreceptors and the risk of Parkinson's disease.

Lancet Neurol 2020 03 27;19(3):247-254. Epub 2020 Jan 27.

Department of Neurology, University Medical Center Schleswig Holstein, Christian-Albrechts-University, Kiel, Germany. Electronic address:

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http://dx.doi.org/10.1016/S1474-4422(19)30400-4DOI Listing
March 2020

Correction to: A nonsynonymous mutation in PLCG2 reduces the risk of Alzheimer's disease, dementia with Lewy bodies and frontotemporal dementia, and increases the likelihood of longevity.

Authors:
Sven J van der Lee Olivia J Conway Iris Jansen Minerva M Carrasquillo Luca Kleineidam Erik van den Akker Isabel Hernández Kristel R van Eijk Najada Stringa Jason A Chen Anna Zettergren Till F M Andlauer Monica Diez-Fairen Javier Simon-Sanchez Alberto Lleó Henrik Zetterberg Marianne Nygaard Cornelis Blauwendraat Jeanne E Savage Jonas Mengel-From Sonia Moreno-Grau Michael Wagner Juan Fortea Michael J Keogh Kaj Blennow Ingmar Skoog Manuel A Friese Olga Pletnikova Miren Zulaica Carmen Lage Itziar de Rojas Steffi Riedel-Heller Ignacio Illán-Gala Wei Wei Bernard Jeune Adelina Orellana Florian Then Bergh Xue Wang Marc Hulsman Nina Beker Niccolo Tesi Christopher M Morris Begoña Indakoetxea Lyduine E Collij Martin Scherer Estrella Morenas-Rodríguez James W Ironside Bart N M van Berckel Daniel Alcolea Heinz Wiendl Samantha L Strickland Pau Pastor Eloy Rodríguez Rodríguez Bradley F Boeve Ronald C Petersen Tanis J Ferman Jay A van Gerpen Marcel J T Reinders Ryan J Uitti Lluís Tárraga Wolfgang Maier Oriol Dols-Icardo Amit Kawalia Maria Carolina Dalmasso Mercè Boada Uwe K Zettl Natasja M van Schoor Marian Beekman Mariet Allen Eliezer Masliah Adolfo López de Munain Alexander Pantelyat Zbigniew K Wszolek Owen A Ross Dennis W Dickson Neill R Graff-Radford David Knopman Rosa Rademakers Afina W Lemstra Yolande A L Pijnenburg Philip Scheltens Thomas Gasser Patrick F Chinnery Bernhard Hemmer Martijn A Huisman Juan Troncoso Fermin Moreno Ellen A Nohr Thorkild I A Sørensen Peter Heutink Pascual Sánchez-Juan Danielle Posthuma Jordi Clarimón Kaare Christensen Nilüfer Ertekin-Taner Sonja W Scholz Alfredo Ramirez Agustín Ruiz Eline Slagboom Wiesje M van der Flier Henne Holstege

Acta Neuropathol 2020 05;139(5):959-962

Alzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1007/s00401-019-02107-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7181435PMC
May 2020

Are Advances in Survival among the Oldest Old Seen across the Spectrum of Health and Functioning?

J Gerontol A Biol Sci Med Sci 2020 Jan 13. Epub 2020 Jan 13.

Danish Aging Research Center, Epidemiology, Biostatistics and Biodemography, Department of Public Health, University of Southern Denmark, J.B. Winsloews Vej, Odense C, Denmark.

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http://dx.doi.org/10.1093/gerona/glaa009DOI Listing
January 2020

Characteristics of Danish Centenarians' Religious Beliefs: A Nationwide Population-Based Study.

J Relig Health 2020 Jan 10. Epub 2020 Jan 10.

Research Unit of General Practice, Department of Public Health, University of Southern Denmark, 5000, Odense, Denmark.

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http://dx.doi.org/10.1007/s10943-020-00981-1DOI Listing
January 2020

Sex differences in health and mortality by income and income changes.

J Epidemiol Community Health 2020 03 16;74(3):225-231. Epub 2019 Dec 16.

Unit of Epidemiology, Biostatistics and Biodemography, Department of Public Health, University of Southern Denmark, Odense, Denmark.

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http://dx.doi.org/10.1136/jech-2019-213096DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7212301PMC
March 2020

Epidemiology of Perceived Physical Fatigability in Older Adults: The Long Life Family Study.

J Gerontol A Biol Sci Med Sci 2020 Sep;75(9):e81-e88

Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania.

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http://dx.doi.org/10.1093/gerona/glz288DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7494027PMC
September 2020

Opposite-sex and same-sex twin studies of physiological, cognitive and behavioral traits.

Neurosci Biobehav Rev 2020 01 8;108:322-340. Epub 2019 Nov 8.

Education Research Institute, Department of Education, Mokpo National University, Jeonnam, South Korea. Electronic address:

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http://dx.doi.org/10.1016/j.neubiorev.2019.11.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6949417PMC
January 2020

Global expression profiling of cognitive level and decline in middle-aged monozygotic twins.

Neurobiol Aging 2019 12 26;84:141-147. Epub 2019 Aug 26.

The Danish Twin Registry and The Danish Aging Research Center, Department of Public Health, University of Southern Denmark, Odense C, Denmark; Department of Clinical Immunology, Copenhagen University Hospital, Rigshospitalet, Copenhagen OE, Denmark.

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http://dx.doi.org/10.1016/j.neurobiolaging.2019.08.019DOI Listing
December 2019

Resting heart rate and mortality in the very old.

Scand J Clin Lab Invest 2019 Dec 3;79(8):566-571. Epub 2019 Oct 3.

Department of Public Health, The Danish Aging Research Center, University of Southern Denmark, Odense, Denmark.

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http://dx.doi.org/10.1080/00365513.2019.1672085DOI Listing
December 2019

The Danish Twin Registry: An Updated Overview.

Twin Res Hum Genet 2019 12 23;22(6):499-507. Epub 2019 Sep 23.

The Danish Twin Registry, Department of Public Health, University of Southern Denmark, Odense, Denmark.

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http://dx.doi.org/10.1017/thg.2019.72DOI Listing
December 2019

A meta-analysis of genome-wide association studies identifies multiple longevity genes.

Nat Commun 2019 08 14;10(1):3669. Epub 2019 Aug 14.

NHLBI's and Boston University's Framingham Heart Study, Framingham, MA, 01702, USA.

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http://dx.doi.org/10.1038/s41467-019-11558-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6694136PMC
August 2019

Epigenome-wide exploratory study of monozygotic twins suggests differentially methylated regions to associate with hand grip strength.

Biogerontology 2019 10 28;20(5):627-647. Epub 2019 Jun 28.

Epidemiology, Biostatistics and Biodemography, Department of Public Health, University of Southern Denmark, J.B. Winsløws Vej 9B, 5000, Odense C, Denmark.

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http://link.springer.com/10.1007/s10522-019-09818-1
Publisher Site
http://dx.doi.org/10.1007/s10522-019-09818-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733812PMC
October 2019

Sex Differences in Comorbidity and Frailty in Europe.

Int J Public Health 2019 Sep 24;64(7):1025-1036. Epub 2019 Jun 24.

Epidemiology, Biostatistics and Biodemography, Department of Public Health, University of Southern Denmark, J. B. Winsløws Vej 9B, 5000, Odense C, Denmark.

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http://dx.doi.org/10.1007/s00038-019-01270-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7237816PMC
September 2019

A catalog of genetic loci associated with kidney function from analyses of a million individuals.

Authors:
Matthias Wuttke Yong Li Man Li Karsten B Sieber Mary F Feitosa Mathias Gorski Adrienne Tin Lihua Wang Audrey Y Chu Anselm Hoppmann Holger Kirsten Ayush Giri Jin-Fang Chai Gardar Sveinbjornsson Bamidele O Tayo Teresa Nutile Christian Fuchsberger Jonathan Marten Massimiliano Cocca Sahar Ghasemi Yizhe Xu Katrin Horn Damia Noce Peter J van der Most Sanaz Sedaghat Zhi Yu Masato Akiyama Saima Afaq Tarunveer S Ahluwalia Peter Almgren Najaf Amin Johan Ärnlöv Stephan J L Bakker Nisha Bansal Daniela Baptista Sven Bergmann Mary L Biggs Ginevra Biino Michael Boehnke Eric Boerwinkle Mathilde Boissel Erwin P Bottinger Thibaud S Boutin Hermann Brenner Marco Brumat Ralph Burkhardt Adam S Butterworth Eric Campana Archie Campbell Harry Campbell Mickaël Canouil Robert J Carroll Eulalia Catamo John C Chambers Miao-Ling Chee Miao-Li Chee Xu Chen Ching-Yu Cheng Yurong Cheng Kaare Christensen Renata Cifkova Marina Ciullo Maria Pina Concas James P Cook Josef Coresh Tanguy Corre Cinzia Felicita Sala Daniele Cusi John Danesh E Warwick Daw Martin H de Borst Alessandro De Grandi Renée de Mutsert Aiko P J de Vries Frauke Degenhardt Graciela Delgado Ayse Demirkan Emanuele Di Angelantonio Katalin Dittrich Jasmin Divers Rajkumar Dorajoo Kai-Uwe Eckardt Georg Ehret Paul Elliott Karlhans Endlich Michele K Evans Janine F Felix Valencia Hui Xian Foo Oscar H Franco Andre Franke Barry I Freedman Sandra Freitag-Wolf Yechiel Friedlander Philippe Froguel Ron T Gansevoort He Gao Paolo Gasparini J Michael Gaziano Vilmantas Giedraitis Christian Gieger Giorgia Girotto Franco Giulianini Martin Gögele Scott D Gordon Daniel F Gudbjartsson Vilmundur Gudnason Toomas Haller Pavel Hamet Tamara B Harris Catharina A Hartman Caroline Hayward Jacklyn N Hellwege Chew-Kiat Heng Andrew A Hicks Edith Hofer Wei Huang Nina Hutri-Kähönen Shih-Jen Hwang M Arfan Ikram Olafur S Indridason Erik Ingelsson Marcus Ising Vincent W V Jaddoe Johanna Jakobsdottir Jost B Jonas Peter K Joshi Navya Shilpa Josyula Bettina Jung Mika Kähönen Yoichiro Kamatani Candace M Kammerer Masahiro Kanai Mika Kastarinen Shona M Kerr Chiea-Chuen Khor Wieland Kiess Marcus E Kleber Wolfgang Koenig Jaspal S Kooner Antje Körner Peter Kovacs Aldi T Kraja Alena Krajcoviechova Holly Kramer Bernhard K Krämer Florian Kronenberg Michiaki Kubo Brigitte Kühnel Mikko Kuokkanen Johanna Kuusisto Martina La Bianca Markku Laakso Leslie A Lange Carl D Langefeld Jeannette Jen-Mai Lee Benjamin Lehne Terho Lehtimäki Wolfgang Lieb Su-Chi Lim Lars Lind Cecilia M Lindgren Jun Liu Jianjun Liu Markus Loeffler Ruth J F Loos Susanne Lucae Mary Ann Lukas Leo-Pekka Lyytikäinen Reedik Mägi Patrik K E Magnusson Anubha Mahajan Nicholas G Martin Jade Martins Winfried März Deborah Mascalzoni Koichi Matsuda Christa Meisinger Thomas Meitinger Olle Melander Andres Metspalu Evgenia K Mikaelsdottir Yuri Milaneschi Kozeta Miliku Pashupati P Mishra Karen L Mohlke Nina Mononen Grant W Montgomery Dennis O Mook-Kanamori Josyf C Mychaleckyj Girish N Nadkarni Mike A Nalls Matthias Nauck Kjell Nikus Boting Ning Ilja M Nolte Raymond Noordam Jeffrey O'Connell Michelle L O'Donoghue Isleifur Olafsson Albertine J Oldehinkel Marju Orho-Melander Willem H Ouwehand Sandosh Padmanabhan Nicholette D Palmer Runolfur Palsson Brenda W J H Penninx Thomas Perls Markus Perola Mario Pirastu Nicola Pirastu Giorgio Pistis Anna I Podgornaia Ozren Polasek Belen Ponte David J Porteous Tanja Poulain Peter P Pramstaller Michael H Preuss Bram P Prins Michael A Province Ton J Rabelink Laura M Raffield Olli T Raitakari Dermot F Reilly Rainer Rettig Myriam Rheinberger Kenneth M Rice Paul M Ridker Fernando Rivadeneira Federica Rizzi David J Roberts Antonietta Robino Peter Rossing Igor Rudan Rico Rueedi Daniela Ruggiero Kathleen A Ryan Yasaman Saba Charumathi Sabanayagam Veikko Salomaa Erika Salvi Kai-Uwe Saum Helena Schmidt Reinhold Schmidt Ben Schöttker Christina-Alexandra Schulz Nicole Schupf Christian M Shaffer Yuan Shi Albert V Smith Blair H Smith Nicole Soranzo Cassandra N Spracklen Konstantin Strauch Heather M Stringham Michael Stumvoll Per O Svensson Silke Szymczak E-Shyong Tai Salman M Tajuddin Nicholas Y Q Tan Kent D Taylor Andrej Teren Yih-Chung Tham Joachim Thiery Chris H L Thio Hauke Thomsen Gudmar Thorleifsson Daniela Toniolo Anke Tönjes Johanne Tremblay Ioanna Tzoulaki André G Uitterlinden Simona Vaccargiu Rob M van Dam Pim van der Harst Cornelia M van Duijn Digna R Velez Edward Niek Verweij Suzanne Vogelezang Uwe Völker Peter Vollenweider Gerard Waeber Melanie Waldenberger Lars Wallentin Ya Xing Wang Chaolong Wang Dawn M Waterworth Wen Bin Wei Harvey White John B Whitfield Sarah H Wild James F Wilson Mary K Wojczynski Charlene Wong Tien-Yin Wong Liang Xu Qiong Yang Masayuki Yasuda Laura M Yerges-Armstrong Weihua Zhang Alan B Zonderman Jerome I Rotter Murielle Bochud Bruce M Psaty Veronique Vitart James G Wilson Abbas Dehghan Afshin Parsa Daniel I Chasman Kevin Ho Andrew P Morris Olivier Devuyst Shreeram Akilesh Sarah A Pendergrass Xueling Sim Carsten A Böger Yukinori Okada Todd L Edwards Harold Snieder Kari Stefansson Adriana M Hung Iris M Heid Markus Scholz Alexander Teumer Anna Köttgen Cristian Pattaro

Nat Genet 2019 06 31;51(6):957-972. Epub 2019 May 31.

Eurac Research, Institute for Biomedicine (affiliated with the University of Lübeck), Bolzano, Italy.

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http://dx.doi.org/10.1038/s41588-019-0407-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6698888PMC
June 2019

A nonsynonymous mutation in PLCG2 reduces the risk of Alzheimer's disease, dementia with Lewy bodies and frontotemporal dementia, and increases the likelihood of longevity.

Authors:
Sven J van der Lee Olivia J Conway Iris Jansen Minerva M Carrasquillo Luca Kleineidam Erik van den Akker Isabel Hernández Kristel R van Eijk Najada Stringa Jason A Chen Anna Zettergren Till F M Andlauer Monica Diez-Fairen Javier Simon-Sanchez Alberto Lleó Henrik Zetterberg Marianne Nygaard Cornelis Blauwendraat Jeanne E Savage Jonas Mengel-From Sonia Moreno-Grau Michael Wagner Juan Fortea Michael J Keogh Kaj Blennow Ingmar Skoog Manuel A Friese Olga Pletnikova Miren Zulaica Carmen Lage Itziar de Rojas Steffi Riedel-Heller Ignacio Illán-Gala Wei Wei Bernard Jeune Adelina Orellana Florian Then Bergh Xue Wang Marc Hulsman Nina Beker Niccolo Tesi Christopher M Morris Begoña Indakoetxea Lyduine E Collij Martin Scherer Estrella Morenas-Rodríguez James W Ironside Bart N M van Berckel Daniel Alcolea Heinz Wiendl Samantha L Strickland Pau Pastor Eloy Rodríguez Rodríguez Bradley F Boeve Ronald C Petersen Tanis J Ferman Jay A van Gerpen Marcel J T Reinders Ryan J Uitti Lluís Tárraga Wolfgang Maier Oriol Dols-Icardo Amit Kawalia Maria Carolina Dalmasso Mercè Boada Uwe K Zettl Natasja M van Schoor Marian Beekman Mariet Allen Eliezer Masliah Adolfo López de Munain Alexander Pantelyat Zbigniew K Wszolek Owen A Ross Dennis W Dickson Neill R Graff-Radford David Knopman Rosa Rademakers Afina W Lemstra Yolande A L Pijnenburg Philip Scheltens Thomas Gasser Patrick F Chinnery Bernhard Hemmer Martijn A Huisman Juan Troncoso Fermin Moreno Ellen A Nohr Thorkild I A Sørensen Peter Heutink Pascual Sánchez-Juan Danielle Posthuma Jordi Clarimón Kaare Christensen Nilüfer Ertekin-Taner Sonja W Scholz Alfredo Ramirez Agustín Ruiz Eline Slagboom Wiesje M van der Flier Henne Holstege

Acta Neuropathol 2019 08 27;138(2):237-250. Epub 2019 May 27.

Alzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1007/s00401-019-02026-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6660501PMC
August 2019

Use of β2-adrenoreceptor agonist and antagonist drugs and risk of Parkinson disease.

Neurology 2019 07 24;93(2):e135-e142. Epub 2019 May 24.

From the Department of Psychiatry and Psychotherapy (F.H.), Ludwig-Maximilians-Universität München, Germany; Department of Neurology (F.H., G.K., G.D.), UKSH, Christian-Albrechts-University Kiel, Germany; Unit of Epidemiology, Biostatistics and Biodemography (M.W., K.C.), Danish Twin Registry (M.W., K.C.), Danish Aging Research Center (M.W., K.C.), and Department of Clinical Research (M.B.) and Clinical Pharmacology and Pharmacy (A.P.), Department of Public Health, University of Southern Denmark, Odense; Department of Neurology (G.U.H.), Hannover Medical School, Germany; Department of Neurology (G.U.H., T.W.R.), Technical University of Munich; German Center for Neurodegenerative Diseases (G.U.H., T.W.R.); Munich Cluster for Systems Neurology (G.U.H., T.W.R.), Germany; and Departments of Neurology (M.B.), Clinical Genetics (K.C.), and Clinical Biochemistry and Pharmacology (K.C.), Odense University Hospital, Denmark.

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http://dx.doi.org/10.1212/WNL.0000000000007694DOI Listing
July 2019

Cancer Incidence and Mortality in 260,000 Nordic Twins With 30,000 Prospective Cancers.

Twin Res Hum Genet 2019 04 25;22(2):99-107. Epub 2019 Apr 25.

Department of Social Sciences,University of Tampere,Tampere,Finland.

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http://dx.doi.org/10.1017/thg.2019.10DOI Listing
April 2019

Parallel Progress in Perceived Age and Life Expectancy.

J Gerontol A Biol Sci Med Sci 2020 01;75(2):333-339

Institute of Public Health, The Danish Aging Research Center, University of Southern Denmark, Odense, Denmark.

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http://dx.doi.org/10.1093/gerona/glz096DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7530473PMC
January 2020

Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids.

Authors:
Amy R Bentley Yun J Sung Michael R Brown Thomas W Winkler Aldi T Kraja Ioanna Ntalla Karen Schwander Daniel I Chasman Elise Lim Xuan Deng Xiuqing Guo Jingmin Liu Yingchang Lu Ching-Yu Cheng Xueling Sim Dina Vojinovic Jennifer E Huffman Solomon K Musani Changwei Li Mary F Feitosa Melissa A Richard Raymond Noordam Jenna Baker Guanjie Chen Hugues Aschard Traci M Bartz Jingzhong Ding Rajkumar Dorajoo Alisa K Manning Tuomo Rankinen Albert V Smith Salman M Tajuddin Wei Zhao Mariaelisa Graff Maris Alver Mathilde Boissel Jin Fang Chai Xu Chen Jasmin Divers Evangelos Evangelou Chuan Gao Anuj Goel Yanick Hagemeijer Sarah E Harris Fernando P Hartwig Meian He Andrea R V R Horimoto Fang-Chi Hsu Yi-Jen Hung Anne U Jackson Anuradhani Kasturiratne Pirjo Komulainen Brigitte Kühnel Karin Leander Keng-Hung Lin Jian'an Luan Leo-Pekka Lyytikäinen Nana Matoba Ilja M Nolte Maik Pietzner Bram Prins Muhammad Riaz Antonietta Robino M Abdullah Said Nicole Schupf Robert A Scott Tamar Sofer Alena Stancáková Fumihiko Takeuchi Bamidele O Tayo Peter J van der Most Tibor V Varga Tzung-Dau Wang Yajuan Wang Erin B Ware Wanqing Wen Yong-Bing Xiang Lisa R Yanek Weihua Zhang Jing Hua Zhao Adebowale Adeyemo Saima Afaq Najaf Amin Marzyeh Amini Dan E Arking Zorayr Arzumanyan Tin Aung Christie Ballantyne R Graham Barr Lawrence F Bielak Eric Boerwinkle Erwin P Bottinger Ulrich Broeckel Morris Brown Brian E Cade Archie Campbell Mickaël Canouil Sabanayagam Charumathi Yii-Der Ida Chen Kaare Christensen Maria Pina Concas John M Connell Lisa de Las Fuentes H Janaka de Silva Paul S de Vries Ayo Doumatey Qing Duan Charles B Eaton Ruben N Eppinga Jessica D Faul James S Floyd Nita G Forouhi Terrence Forrester Yechiel Friedlander Ilaria Gandin He Gao Mohsen Ghanbari Sina A Gharib Bruna Gigante Franco Giulianini Hans J Grabe C Charles Gu Tamara B Harris Sami Heikkinen Chew-Kiat Heng Makoto Hirata James E Hixson M Arfan Ikram Yucheng Jia Roby Joehanes Craig Johnson Jost Bruno Jonas Anne E Justice Tomohiro Katsuya Chiea Chuen Khor Tuomas O Kilpeläinen Woon-Puay Koh Ivana Kolcic Charles Kooperberg Jose E Krieger Stephen B Kritchevsky Michiaki Kubo Johanna Kuusisto Timo A Lakka Carl D Langefeld Claudia Langenberg Lenore J Launer Benjamin Lehne Cora E Lewis Yize Li Jingjing Liang Shiow Lin Ching-Ti Liu Jianjun Liu Kiang Liu Marie Loh Kurt K Lohman Tin Louie Anna Luzzi Reedik Mägi Anubha Mahajan Ani W Manichaikul Colin A McKenzie Thomas Meitinger Andres Metspalu Yuri Milaneschi Lili Milani Karen L Mohlke Yukihide Momozawa Andrew P Morris Alison D Murray Mike A Nalls Matthias Nauck Christopher P Nelson Kari E North Jeffrey R O'Connell Nicholette D Palmer George J Papanicolau Nancy L Pedersen Annette Peters Patricia A Peyser Ozren Polasek Neil Poulter Olli T Raitakari Alex P Reiner Frida Renström Treva K Rice Stephen S Rich Jennifer G Robinson Lynda M Rose Frits R Rosendaal Igor Rudan Carsten O Schmidt Pamela J Schreiner William R Scott Peter Sever Yuan Shi Stephen Sidney Mario Sims Jennifer A Smith Harold Snieder John M Starr Konstantin Strauch Heather M Stringham Nicholas Y Q Tan Hua Tang Kent D Taylor Yik Ying Teo Yih Chung Tham Henning Tiemeier Stephen T Turner André G Uitterlinden Diana van Heemst Melanie Waldenberger Heming Wang Lan Wang Lihua Wang Wen Bin Wei Christine A Williams Gregory Wilson Mary K Wojczynski Jie Yao Kristin Young Caizheng Yu Jian-Min Yuan Jie Zhou Alan B Zonderman Diane M Becker Michael Boehnke Donald W Bowden John C Chambers Richard S Cooper Ulf de Faire Ian J Deary Paul Elliott Tõnu Esko Martin Farrall Paul W Franks Barry I Freedman Philippe Froguel Paolo Gasparini Christian Gieger Bernardo L Horta Jyh-Ming Jimmy Juang Yoichiro Kamatani Candace M Kammerer Norihiro Kato Jaspal S Kooner Markku Laakso Cathy C Laurie I-Te Lee Terho Lehtimäki Patrik K E Magnusson Albertine J Oldehinkel Brenda W J H Penninx Alexandre C Pereira Rainer Rauramaa Susan Redline Nilesh J Samani James Scott Xiao-Ou Shu Pim van der Harst Lynne E Wagenknecht Jun-Sing Wang Ya Xing Wang Nicholas J Wareham Hugh Watkins David R Weir Ananda R Wickremasinghe Tangchun Wu Eleftheria Zeggini Wei Zheng Claude Bouchard Michele K Evans Vilmundur Gudnason Sharon L R Kardia Yongmei Liu Bruce M Psaty Paul M Ridker Rob M van Dam Dennis O Mook-Kanamori Myriam Fornage Michael A Province Tanika N Kelly Ervin R Fox Caroline Hayward Cornelia M van Duijn E Shyong Tai Tien Yin Wong Ruth J F Loos Nora Franceschini Jerome I Rotter Xiaofeng Zhu Laura J Bierut W James Gauderman Kenneth Rice Patricia B Munroe Alanna C Morrison Dabeeru C Rao Charles N Rotimi L Adrienne Cupples

Nat Genet 2019 04 29;51(4):636-648. Epub 2019 Mar 29.

Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA.

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http://dx.doi.org/10.1038/s41588-019-0378-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6467258PMC
April 2019

Advanced Parental Age at Conception and Sex Affects Mitochondrial DNA Copy Number in Human and Fruit Flies.

J Gerontol A Biol Sci Med Sci 2019 11;74(12):1853-1860

The Danish Aging Research Center and The Danish Twin Registry, Epidemiology and Biostatistics Unit, Institute of Public Health, University of Southern Denmark, Odense.

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https://academic.oup.com/biomedgerontology/advance-article/d
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http://dx.doi.org/10.1093/gerona/glz070DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7357451PMC
November 2019

Diagnosing heart failure in centenarians.

J Geriatr Cardiol 2019 Jan;16(1):1-11

Department of Cardiology, Odense University Hospital, Odense, Denmark.

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http://dx.doi.org/10.11909/j.issn.1671-5411.2019.01.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6379242PMC
January 2019

Declining cancer incidence at the oldest ages: Hallmark of aging or lower diagnostic activity?

J Geriatr Oncol 2019 09 21;10(5):792-798. Epub 2019 Feb 21.

Academy of Geriatric Cancer Research (AgeCare), Odense, Denmark; The Danish Aging Research Center (KC), Department of Epidemiology, Biostatistics and Biodemography, Institute of Public Health, University of Southern Denmark, Odense, Denmark.

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http://dx.doi.org/10.1016/j.jgo.2019.02.001DOI Listing
September 2019

Age-dependent DNA methylation patterns on the Y chromosome in elderly males.

Aging Cell 2020 02 21;19(2):e12907. Epub 2019 Feb 21.

Epidemiology and Biostatistics, Department of Public Health, University of Southern Denmark, Odense, Denmark.

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http://doi.wiley.com/10.1111/acel.12907
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http://dx.doi.org/10.1111/acel.12907DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6996942PMC
February 2020

Lifespans of Twins: Does Zygosity Matter?

Genes (Basel) 2019 02 20;10(2). Epub 2019 Feb 20.

Department of Epidemiology and Biostatistics, University of Southern Denmark, DK-5000 Odense, Denmark.

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http://dx.doi.org/10.3390/genes10020166DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6409769PMC
February 2019

DNA methylome profiling of all-cause mortality in comparison with age-associated methylation patterns.

Clin Epigenetics 2019 02 8;11(1):23. Epub 2019 Feb 8.

Epidemiology and Biostatistics, Department of Public Health, Faculty of Health Science, University of Southern Denmark, J. B. Winsløws Vej 9B, DK-5000, Odense, Denmark.

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http://dx.doi.org/10.1186/s13148-019-0622-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6368749PMC
February 2019

A novel healthy metabolic phenotype developed among a cohort of families enriched for longevity.

Metabolism 2019 05 30;94:28-38. Epub 2019 Jan 30.

Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, USA; Departments of Medicine and Clinical and Translational Science, University of Pittsburgh, Pittsburgh, PA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.metabol.2019.01.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7099575PMC
May 2019

A Cohort Comparison of Lifespan After Age 100 in Denmark and Sweden: Are Only the Oldest Getting Older?

Demography 2019 04;56(2):665-677

Interdisciplinary Center on Population Dynamics, University of Southern Denmark, Odense, Denmark.

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http://dx.doi.org/10.1007/s13524-018-0755-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6449298PMC
April 2019

Associations of Mitochondrial and Nuclear Mitochondrial Variants and Genes with Seven Metabolic Traits.

Authors:
Aldi T Kraja Chunyu Liu Jessica L Fetterman Mariaelisa Graff Christian Theil Have Charles Gu Lisa R Yanek Mary F Feitosa Dan E Arking Daniel I Chasman Kristin Young Symen Ligthart W David Hill Stefan Weiss Jian'an Luan Franco Giulianini Ruifang Li-Gao Fernando P Hartwig Shiow J Lin Lihua Wang Tom G Richardson Jie Yao Eliana P Fernandez Mohsen Ghanbari Mary K Wojczynski Wen-Jane Lee Maria Argos Sebastian M Armasu Ruteja A Barve Kathleen A Ryan Ping An Thomas J Baranski Suzette J Bielinski Donald W Bowden Ulrich Broeckel Kaare Christensen Audrey Y Chu Janie Corley Simon R Cox Andre G Uitterlinden Fernando Rivadeneira Cheryl D Cropp E Warwick Daw Diana van Heemst Lisa de Las Fuentes He Gao Ioanna Tzoulaki Tarunveer S Ahluwalia Renée de Mutsert Leslie S Emery A Mesut Erzurumluoglu James A Perry Mao Fu Nita G Forouhi Zhenglong Gu Yang Hai Sarah E Harris Gibran Hemani Steven C Hunt Marguerite R Irvin Anna E Jonsson Anne E Justice Nicola D Kerrison Nicholas B Larson Keng-Hung Lin Latisha D Love-Gregory Rasika A Mathias Joseph H Lee Matthias Nauck Raymond Noordam Ken K Ong James Pankow Amit Patki Alison Pattie Astrid Petersmann Qibin Qi Rasmus Ribel-Madsen Rebecca Rohde Kevin Sandow Theresia M Schnurr Tamar Sofer John M Starr Adele M Taylor Alexander Teumer Nicholas J Timpson Hugoline G de Haan Yujie Wang Peter E Weeke Christine Williams Hongsheng Wu Wei Yang Donglin Zeng Daniel R Witte Bruce S Weir Nicholas J Wareham Henrik Vestergaard Stephen T Turner Christian Torp-Pedersen Evie Stergiakouli Wayne Huey-Herng Sheu Frits R Rosendaal M Arfan Ikram Oscar H Franco Paul M Ridker Thomas T Perls Oluf Pedersen Ellen A Nohr Anne B Newman Allan Linneberg Claudia Langenberg Tuomas O Kilpeläinen Sharon L R Kardia Marit E Jørgensen Torben Jørgensen Thorkild I A Sørensen Georg Homuth Torben Hansen Mark O Goodarzi Ian J Deary Cramer Christensen Yii-Der Ida Chen Aravinda Chakravarti Ivan Brandslund Klaus Bonnelykke Kent D Taylor James G Wilson Santiago Rodriguez Gail Davies Bernardo L Horta Bharat Thyagarajan D C Rao Niels Grarup Victor G Davila-Roman Gavin Hudson Xiuqing Guo Donna K Arnett Caroline Hayward Dhananjay Vaidya Dennis O Mook-Kanamori Hemant K Tiwari Daniel Levy Ruth J F Loos Abbas Dehghan Paul Elliott Afshan N Malik Robert A Scott Diane M Becker Mariza de Andrade Michael A Province James B Meigs Jerome I Rotter Kari E North

Am J Hum Genet 2019 01 27;104(1):112-138. Epub 2018 Dec 27.

Department of Epidemiology, University of North Carolina, Chapel Hill, NC 27516, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2018.12.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6323610PMC
January 2019

Gender differences in cognitive function and grip strength: a cross-national comparison of four European regions.

Eur J Public Health 2019 08;29(4):667-674

Unit of Epidemiology, Biostatistics and Biodemography, Department of Public Health, University of Southern Denmark, Odense, Denmark.

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http://dx.doi.org/10.1093/eurpub/cky266DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6660112PMC
August 2019

Independent associations of TOMM40 and APOE variants with body mass index.

Aging Cell 2019 02 21;18(1):e12869. Epub 2018 Nov 21.

Biodemography of Aging Research Unit, Social Science Research Institute, Duke University, Durham, North California.

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http://dx.doi.org/10.1111/acel.12869DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6351823PMC
February 2019

Hearing loss, cognitive ability, and dementia in men age 19-78 years.

Eur J Epidemiol 2019 Feb 10;34(2):125-130. Epub 2018 Oct 10.

Department of Public Health, University of Copenhagen, Copenhagen, Denmark.

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http://link.springer.com/10.1007/s10654-018-0452-2
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http://dx.doi.org/10.1007/s10654-018-0452-2DOI Listing
February 2019

Sex Differences in Genetic Associations With Longevity.

JAMA Netw Open 2018 08 24;1(4):e181670. Epub 2018 Aug 24.

Center for the Study of Aging and Human Development, Medical School of Duke University, Durham, North Carolina (Zeng, H. Chen); Center for Healthy Aging and Development Studies, National School of Development, Raissun Institute for Advanced Studies, Peking University, Beijing, China (Zeng, Bai); BGI Education Center, University of Chinese Academy of Sciences, Shenzhen, China (Nie);BGI-Shenzhen, Shenzhen, China (Nie, Xiaomin Liu, Ye, Z. Chen, Bolund, Hou, Xiao Liu, Xu, H. Yang); The First Affiliated Hospital, Institute of Translational Medicine, School of Medicine, Zhejiang University, Hangzhou, China (Min, E. Xie); Business School of Xiangtan University, Xiangtan, China (H. Chen); Division of Non-Communicable Disease Control and Community Health, Chinese Center for Disease Control and Prevention, Beijing, China (Yin); National Institute of Environmental Health, Chinese Center for Disease Control and Prevention, Beijing, China (Lv, Shi); Department of Sociology, Peking University, Beijing, China (Lu, Li); School of Life Sciences, Fudan University, Shanghai, China (Ni); Department of Biomedicine, Aarhus University, Aarhus, Denmark (Bolund); Duke Population Research Institute, Duke University, Durham, North Carolina (Land, Yashin, O'Rand); The MOH Key Laboratory of Geriatrics, Beijing Hospital, National Center of Gerontology, Beijing, China (Sun, Z. Yang); School of Life Sciences, Peking University, Beijing, China (Tao, Gu); Boston University, Boston, Massachusetts (Gurinovich, Sebastiani, Perls); University of Bologna, Bologna, Italy (Franceschi); Department of Biostatistics and Bioinformatics, Duke University, Durham, North Carolina (J. Xie); French National Institute on Health and Medical Research and Ecole Pratique des Hautes Etudes, University of Montpellier, Montpellier, France (Robine); Max Planck Institute for Biology of Ageing, Cologne, Germany (Deelen); Department of Molecular Epidemiology, Leiden University Medical Center, Leiden, the Netherlands (Slagboom); Molecular Physiology Institute, Medical Center, Duke University, Durham, North Carolina (Hauser); Department of Neurology, Medical Center, Duke University, Durham, North Carolina (Gottschalk, Lutz); University of Southern Denmark, Odense, Denmark (Tan, Christensen); Human Aging Research Institute and School of Life Science, Nanchang University, Jiangxi, China (Tian); James D. Watson Institute of Genome Sciences, Hangzhou, China (H. Yang); Max Planck Institute for Demographic Research, Rostock, Germany (Vaupel).

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http://dx.doi.org/10.1001/jamanetworkopen.2018.1670DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6173523PMC
August 2018

Multiethnic meta-analysis identifies ancestry-specific and cross-ancestry loci for pulmonary function.

Authors:
Annah B Wyss Tamar Sofer Mi Kyeong Lee Natalie Terzikhan Jennifer N Nguyen Lies Lahousse Jeanne C Latourelle Albert Vernon Smith Traci M Bartz Mary F Feitosa Wei Gao Tarunveer S Ahluwalia Wenbo Tang Christopher Oldmeadow Qing Duan Kim de Jong Mary K Wojczynski Xin-Qun Wang Raymond Noordam Fernando Pires Hartwig Victoria E Jackson Tianyuan Wang Ma'en Obeidat Brian D Hobbs Tianxiao Huan Hongsheng Gui Margaret M Parker Donglei Hu Lauren S Mogil Gleb Kichaev Jianping Jin Mariaelisa Graff Tamara B Harris Ravi Kalhan Susan R Heckbert Lavinia Paternoster Kristin M Burkart Yongmei Liu Elizabeth G Holliday James G Wilson Judith M Vonk Jason L Sanders R Graham Barr Renée de Mutsert Ana Maria Baptista Menezes Hieab H H Adams Maarten van den Berge Roby Joehanes Albert M Levin Jennifer Liberto Lenore J Launer Alanna C Morrison Colleen M Sitlani Juan C Celedón Stephen B Kritchevsky Rodney J Scott Kaare Christensen Jerome I Rotter Tobias N Bonten Fernando César Wehrmeister Yohan Bossé Shujie Xiao Sam Oh Nora Franceschini Jennifer A Brody Robert C Kaplan Kurt Lohman Mark McEvoy Michael A Province Frits R Rosendaal Kent D Taylor David C Nickle L Keoki Williams Esteban G Burchard Heather E Wheeler Don D Sin Vilmundur Gudnason Kari E North Myriam Fornage Bruce M Psaty Richard H Myers George O'Connor Torben Hansen Cathy C Laurie Patricia A Cassano Joohon Sung Woo Jin Kim John R Attia Leslie Lange H Marike Boezen Bharat Thyagarajan Stephen S Rich Dennis O Mook-Kanamori Bernardo Lessa Horta André G Uitterlinden Hae Kyung Im Michael H Cho Guy G Brusselle Sina A Gharib Josée Dupuis Ani Manichaikul Stephanie J London

Nat Commun 2018 07 30;9(1):2976. Epub 2018 Jul 30.

Epidemiology Branch National Institute of Environmental Health Sciences, National Institutes of Health, US Department of Health and Human Services, Research Triangle Park, NC, 27709, USA.

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http://dx.doi.org/10.1038/s41467-018-05369-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6065313PMC
July 2018

Irving I. Gottesman's Collaboration in Psychiatric Genetics Research in Denmark.

Twin Res Hum Genet 2018 08;21(4):322-323

Translational Neuropsychiatry Unit,Department of Clinical Medicine,University of Aarhus,Risskov,Denmark.

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http://dx.doi.org/10.1017/thg.2018.32DOI Listing
August 2018

Whole exome sequencing reveals HSPA1L as a genetic risk factor for spontaneous preterm birth.

PLoS Genet 2018 07 12;14(7):e1007394. Epub 2018 Jul 12.

Division of Human Genetics, Center for Prevention of Preterm Birth, Perinatal Institute, Cincinnati Children's Hospital Medical Center, Department of Pediatrics, University of Cincinnati College of Medicine, March of Dimes Prematurity Research Center Ohio Collaborative, Cincinnati, Ohio, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1007394DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6042692PMC
July 2018

Epigenetic signature of preterm birth in adult twins.

Clin Epigenetics 2018 27;10:87. Epub 2018 Jun 27.

1Epidemiology and Biostatistics, Department of Public Health, Faculty of Health Science, University of Southern Denmark, J. B. Winsløws Vej 9B, DK-5000 Odense, Denmark.

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http://dx.doi.org/10.1186/s13148-018-0518-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6020425PMC
July 2019

Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries.

Authors:
Mary F Feitosa Aldi T Kraja Daniel I Chasman Yun J Sung Thomas W Winkler Ioanna Ntalla Xiuqing Guo Nora Franceschini Ching-Yu Cheng Xueling Sim Dina Vojinovic Jonathan Marten Solomon K Musani Changwei Li Amy R Bentley Michael R Brown Karen Schwander Melissa A Richard Raymond Noordam Hugues Aschard Traci M Bartz Lawrence F Bielak Rajkumar Dorajoo Virginia Fisher Fernando P Hartwig Andrea R V R Horimoto Kurt K Lohman Alisa K Manning Tuomo Rankinen Albert V Smith Salman M Tajuddin Mary K Wojczynski Maris Alver Mathilde Boissel Qiuyin Cai Archie Campbell Jin Fang Chai Xu Chen Jasmin Divers Chuan Gao Anuj Goel Yanick Hagemeijer Sarah E Harris Meian He Fang-Chi Hsu Anne U Jackson Mika Kähönen Anuradhani Kasturiratne Pirjo Komulainen Brigitte Kühnel Federica Laguzzi Jian'an Luan Nana Matoba Ilja M Nolte Sandosh Padmanabhan Muhammad Riaz Rico Rueedi Antonietta Robino M Abdullah Said Robert A Scott Tamar Sofer Alena Stančáková Fumihiko Takeuchi Bamidele O Tayo Peter J van der Most Tibor V Varga Veronique Vitart Yajuan Wang Erin B Ware Helen R Warren Stefan Weiss Wanqing Wen Lisa R Yanek Weihua Zhang Jing Hua Zhao Saima Afaq Najaf Amin Marzyeh Amini Dan E Arking Tin Aung Eric Boerwinkle Ingrid Borecki Ulrich Broeckel Morris Brown Marco Brumat Gregory L Burke Mickaël Canouil Aravinda Chakravarti Sabanayagam Charumathi Yii-Der Ida Chen John M Connell Adolfo Correa Lisa de Las Fuentes Renée de Mutsert H Janaka de Silva Xuan Deng Jingzhong Ding Qing Duan Charles B Eaton Georg Ehret Ruben N Eppinga Evangelos Evangelou Jessica D Faul Stephan B Felix Nita G Forouhi Terrence Forrester Oscar H Franco Yechiel Friedlander Ilaria Gandin He Gao Mohsen Ghanbari Bruna Gigante C Charles Gu Dongfeng Gu Saskia P Hagenaars Göran Hallmans Tamara B Harris Jiang He Sami Heikkinen Chew-Kiat Heng Makoto Hirata Barbara V Howard M Arfan Ikram Ulrich John Tomohiro Katsuya Chiea Chuen Khor Tuomas O Kilpeläinen Woon-Puay Koh José E Krieger Stephen B Kritchevsky Michiaki Kubo Johanna Kuusisto Timo A Lakka Carl D Langefeld Claudia Langenberg Lenore J Launer Benjamin Lehne Cora E Lewis Yize Li Shiow Lin Jianjun Liu Jingmin Liu Marie Loh Tin Louie Reedik Mägi Colin A McKenzie Thomas Meitinger Andres Metspalu Yuri Milaneschi Lili Milani Karen L Mohlke Yukihide Momozawa Mike A Nalls Christopher P Nelson Nona Sotoodehnia Jill M Norris Jeff R O'Connell Nicholette D Palmer Thomas Perls Nancy L Pedersen Annette Peters Patricia A Peyser Neil Poulter Leslie J Raffel Olli T Raitakari Kathryn Roll Lynda M Rose Frits R Rosendaal Jerome I Rotter Carsten O Schmidt Pamela J Schreiner Nicole Schupf William R Scott Peter S Sever Yuan Shi Stephen Sidney Mario Sims Colleen M Sitlani Jennifer A Smith Harold Snieder John M Starr Konstantin Strauch Heather M Stringham Nicholas Y Q Tan Hua Tang Kent D Taylor Yik Ying Teo Yih Chung Tham Stephen T Turner André G Uitterlinden Peter Vollenweider Melanie Waldenberger Lihua Wang Ya Xing Wang Wen Bin Wei Christine Williams Jie Yao Caizheng Yu Jian-Min Yuan Wei Zhao Alan B Zonderman Diane M Becker Michael Boehnke Donald W Bowden John C Chambers Ian J Deary Tõnu Esko Martin Farrall Paul W Franks Barry I Freedman Philippe Froguel Paolo Gasparini Christian Gieger Jost Bruno Jonas Yoichiro Kamatani Norihiro Kato Jaspal S Kooner Zoltán Kutalik Markku Laakso Cathy C Laurie Karin Leander Terho Lehtimäki Lifelines Cohort Study Patrik K E Magnusson Albertine J Oldehinkel Brenda W J H Penninx Ozren Polasek David J Porteous Rainer Rauramaa Nilesh J Samani James Scott Xiao-Ou Shu Pim van der Harst Lynne E Wagenknecht Nicholas J Wareham Hugh Watkins David R Weir Ananda R Wickremasinghe Tangchun Wu Wei Zheng Claude Bouchard Kaare Christensen Michele K Evans Vilmundur Gudnason Bernardo L Horta Sharon L R Kardia Yongmei Liu Alexandre C Pereira Bruce M Psaty Paul M Ridker Rob M van Dam W James Gauderman Xiaofeng Zhu Dennis O Mook-Kanamori Myriam Fornage Charles N Rotimi L Adrienne Cupples Tanika N Kelly Ervin R Fox Caroline Hayward Cornelia M van Duijn E Shyong Tai Tien Yin Wong Charles Kooperberg Walter Palmas Kenneth Rice Alanna C Morrison Paul Elliott Mark J Caulfield Patricia B Munroe Dabeeru C Rao Michael A Province Daniel Levy

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0198166PLOS
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