Publications by authors named "Karen Horsburgh"

47Publications

Deficiency of Nrf2 exacerbates white matter damage and microglia/macrophage levels in a mouse model of vascular cognitive impairment.

J Neuroinflammation 2020 Dec 1;17(1):367. Epub 2020 Dec 1.

Centre for Discovery Brain Sciences, University of Edinburgh, Chancellor's Building, 49 Little France Crescent, Edinburgh, EH16 4SB, UK.

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December 2020

Long-term effects of experimental carotid stenosis on hippocampal infarct pathology, neurons and glia and amelioration by environmental enrichment.

Brain Res Bull 2020 10 21;163:72-83. Epub 2020 Jul 21.

Neurovascular Research Group, Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, UK. Electronic address:

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October 2020

4-Sodium phenyl butyric acid has both efficacy and counter-indicative effects in the treatment of Col4a1 disease.

Hum Mol Genet 2019 02;28(4):628-638

Institute of Cardiovascular and Medical Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, UK.

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February 2019

White matter degeneration in vascular and other ageing-related dementias.

J Neurochem 2018 03 9;144(5):617-633. Epub 2018 Jan 9.

Neurovascular Research Group, Institute of Neuroscience, Newcastle University, Newcastle Upon Tyne, UK.

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March 2018

Minocycline reduces microgliosis and improves subcortical white matter function in a model of cerebral vascular disease.

Glia 2018 01 19;66(1):34-46. Epub 2017 Jul 19.

Centre for Neuroregeneration, University of Edinburgh, Chancellor's Building, 49 Little France Crescent, Edinburgh, EH16 4SB, United Kingdom.

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January 2018

Chronic cerebral hypoperfusion alters amyloid-β peptide pools leading to cerebral amyloid angiopathy, microinfarcts and haemorrhages in Tg-SwDI mice.

Clin Sci (Lond) 2017 Aug 24;131(16):2109-2123. Epub 2017 Jul 24.

Centre for Neuroregeneration, University of Edinburgh, Chancellor's Building, 49 Little France Crescent, Edinburgh EH164SB, U.K.

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August 2017

Effects of environmental enrichment on white matter glial responses in a mouse model of chronic cerebral hypoperfusion.

J Neuroinflammation 2017 04 11;14(1):81. Epub 2017 Apr 11.

Neurovascular Research Group, Institute of Neuroscience, Newcastle University, Campus for Ageing and Vitality, Newcastle upon Tyne, NE4 5PL, UK.

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April 2017

The effects of environmental enrichment on white matter pathology in a mouse model of chronic cerebral hypoperfusion.

J Cereb Blood Flow Metab 2018 01 3;38(1):151-165. Epub 2017 Mar 3.

1 Neurovascular Research Group, Institute of Neuroscience, Newcastle University, Newcastle upon Tyne, UK.

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January 2018

Small vessels, dementia and chronic diseases-molecular mechanisms and pathophysiology.

Clin Sci (Lond) 2016 11;130(21):1875-9

Centre for Neuroregeneration, Chancellor's Building, University of Edinburgh, Edinburgh EH16 4SB, U.K.

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November 2016

Gliovascular disruption and cognitive deficits in a mouse model with features of small vessel disease.

J Cereb Blood Flow Metab 2015 Jun 11;35(6):1005-14. Epub 2015 Feb 11.

Centre for Neuroregeneration, Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.

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June 2015