Jya-Wei Cheng

Jya-Wei Cheng

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Jya-Wei Cheng

Jya-Wei Cheng

Publications by authors named "Jya-Wei Cheng"

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Dependence on size and shape of non-nature amino acids in the enhancement of lipopolysaccharide (LPS) neutralizing activities of antimicrobial peptides.

J Colloid Interface Sci 2019 Jan 14;533:492-502. Epub 2018 Aug 14.

Institute of Biotechnology and Department of Medical Science, National Tsing Hua University, Hsinchu 300, Taiwan. Electronic address:

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http://dx.doi.org/10.1016/j.jcis.2018.08.042DOI Listing
January 2019

A novel CXCL8-IP10 hybrid protein is effective in blocking pulmonary pathology in a mouse model of Klebsiella pneumoniae infection.

Int Immunopharmacol 2018 Sep 3;62:40-45. Epub 2018 Jul 3.

Department of Immunology, Dalian Medical University, Dalian 116044, China. Electronic address:

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http://dx.doi.org/10.1016/j.intimp.2018.06.040DOI Listing
September 2018

Cytotoxic effect of interleukin-8 in retinal ganglion cells and its possible mechanisms.

Int J Ophthalmol 2018 18;11(8):1277-1283. Epub 2018 Aug 18.

Department of Immunology, Dalian Medical University, Dalian 116044, Liaoning Province, China.

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http://www.ijo.cn/gjyken/ch/reader/view_abstract.aspx?file_n
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http://dx.doi.org/10.18240/ijo.2018.08.05DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6090122PMC
August 2018

IL-8 antagonist, CXCL8(3-72)K11R/G31P coupled with probiotic exhibit variably enhanced therapeutic potential in ameliorating ulcerative colitis.

Biomed Pharmacother 2018 Jul 24;103:253-261. Epub 2018 Apr 24.

Department of Immunology, Dalian Medical University, Dalian, Liaoning, China. Electronic address:

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http://dx.doi.org/10.1016/j.biopha.2018.04.008DOI Listing
July 2018

High Level Expression and Purification of the Clinically Active Antimicrobial Peptide P-113 in Escherichia coli.

Molecules 2018 Mar 30;23(4). Epub 2018 Mar 30.

Institute of Biotechnology and Department of Medical Science, National Tsing Hua University, Hsinchu 300, Taiwan.

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http://dx.doi.org/10.3390/molecules23040800DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017664PMC
March 2018

Preventive effects of the novel antimicrobial peptide Nal-P-113 in a rat Periodontitis model by limiting the growth of Porphyromonas gingivalis and modulating IL-1β and TNF-α production.

BMC Complement Altern Med 2017 Aug 29;17(1):426. Epub 2017 Aug 29.

Department of Periodontics and Oral Biology, School of Stomatology, China Medical University, Shenyang, 110002, China.

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http://dx.doi.org/10.1186/s12906-017-1931-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5576277PMC
August 2017

Effects of K11R and G31P Mutations on the Structure and Biological Activities of CXCL8: Solution Structure of Human CXCL8K11R/G31P.

Molecules 2017 Jul 21;22(7). Epub 2017 Jul 21.

Institute of Biotechnology and Department of Medical Science, National Tsing Hua University, Hsinchu 300, Taiwan.

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http://dx.doi.org/10.3390/molecules22071229DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152285PMC
July 2017

Role of β-naphthylalanine end-tags in the enhancement of antiendotoxin activities: Solution structure of the antimicrobial peptide S1-Nal-Nal in complex with lipopolysaccharide.

Biochim Biophys Acta Biomembr 2017 Jun 10;1859(6):1114-1123. Epub 2017 Mar 10.

Institute of Biotechnology and Department of Medical Science, National Tsing Hua University, Hsinchu 300, Taiwan. Electronic address:

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http://dx.doi.org/10.1016/j.bbamem.2017.03.007DOI Listing
June 2017

CXCL8 Antagonist Improves Diabetic Nephropathy in Male Mice With Diabetes and Attenuates High Glucose-Induced Mesangial Injury.

Endocrinology 2017 06;158(6):1671-1684

Department of Immunology, Dalian Medical University, Dalian 116011, Liaoning, China.

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http://dx.doi.org/10.1210/en.2016-1781DOI Listing
June 2017

Molecular pathways underlying inhibitory effect of antimicrobial peptide Nal-P-113 on bacteria biofilms formation of Porphyromonas gingivalis W83 by DNA microarray.

BMC Microbiol 2017 Feb 17;17(1):37. Epub 2017 Feb 17.

Department of Periodontics, School of Stomatology, China Medical University, Shenyang, 110002, China.

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http://dx.doi.org/10.1186/s12866-017-0948-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5316201PMC
February 2017

Selection and Characterization of DNA Aptamers Targeting All Four Serotypes of Dengue Viruses.

PLoS One 2015 25;10(6):e0131240. Epub 2015 Jun 25.

Institute of Biotechnology and Department of Life Science, National Tsing Hua University, Hsinchu 300, Taiwan.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0131240PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4482433PMC
April 2016

Novel antimicrobial peptides with high anticancer activity and selectivity.

PLoS One 2015 13;10(5):e0126390. Epub 2015 May 13.

Institute of Biotechnology and Department of Medical Science, National Tsing Hua University, Hsinchu, 300, Taiwan.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0126390PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4430538PMC
February 2016

Efficacy of a novel antimicrobial peptide against periodontal pathogens in both planktonic and polymicrobial biofilm states.

Acta Biomater 2015 Oct 22;25:150-61. Epub 2015 Jul 22.

Department of Periodontology, School of Stomatology, China Medical University, Shenyang 110002, China. Electronic address:

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http://dx.doi.org/10.1016/j.actbio.2015.07.031DOI Listing
October 2015

Ultrashort Antimicrobial Peptides with Antiendotoxin Properties.

Antimicrob Agents Chemother 2015 Aug 1;59(8):5052-6. Epub 2015 Jun 1.

Institute of Biotechnology and Department of Medical Science, National Tsing Hua University, Hsinchu, Taiwan

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http://dx.doi.org/10.1128/AAC.00519-15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4505259PMC
August 2015

ELR-CXC chemokine antagonism and cisplatin co-treatment additively reduce H22 hepatoma tumor progression and ameliorate cisplatin-induced nephrotoxicity.

Oncol Rep 2014 Apr 24;31(4):1599-604. Epub 2014 Jan 24.

Department of Immunology, Dalian Medical University, Dalian 116044, P.R. China.

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http://dx.doi.org/10.3892/or.2014.2996DOI Listing
April 2014

Correlations between membrane immersion depth, orientation, and salt-resistance of tryptophan-rich antimicrobial peptides.

Biochim Biophys Acta 2013 Nov 27;1828(11):2720-8. Epub 2013 Jul 27.

Institute of Biotechnology and Department of Medical Science, National Tsing Hua University, Hsinchu 300, Taiwan.

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http://dx.doi.org/10.1016/j.bbamem.2013.07.020DOI Listing
November 2013

Effect of the antimicrobial peptide D-Nal-Pac-525 on the growth of Streptococcus mutans and its biofilm formation.

J Microbiol Biotechnol 2013 Aug;23(8):1070-5

Department of Biochemistry and Molecular Biology, Dalian Medical University, Dalian 116044, China.

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August 2013

Boosting salt resistance of short antimicrobial peptides.

Antimicrob Agents Chemother 2013 Aug 28;57(8):4050-2. Epub 2013 May 28.

Institute of Biotechnology and Department of Medical Science, National Tsing Hua University, Hsinchu, Taiwan.

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http://aac.asm.org/lookup/doi/10.1128/AAC.00252-13
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http://dx.doi.org/10.1128/AAC.00252-13DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3719776PMC
August 2013

G31P, an antagonist against CXC chemokine receptors 1 and 2, inhibits growth of human prostate cancer cells in nude mice.

Tohoku J Exp Med 2012 10;228(2):147-56

Department of Microbiology, Dalian Medical University, Dailan, PR China.

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October 2012

Easy strategy to increase salt resistance of antimicrobial peptides.

Antimicrob Agents Chemother 2011 Oct 18;55(10):4918-21. Epub 2011 Jul 18.

Institute of Biotechnology and Department of Medical Science, National Tsing Hua University, Hsinchu 300, Taiwan.

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http://aac.asm.org/content/55/10/4918.full.pdf
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http://aac.asm.org/content/early/2011/07/18/AAC.00202-11.ful
Web Search
http://aac.asm.org/cgi/doi/10.1128/AAC.00202-11
Publisher Site
http://dx.doi.org/10.1128/AAC.00202-11DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3186977PMC
October 2011

Rational design of tryptophan-rich antimicrobial peptides with enhanced antimicrobial activities and specificities.

Chembiochem 2010 Nov;11(16):2273-82

Institute of Biotechnology, Department of Life Science, National Tsing Hua University, Hsinchu, Taiwan.

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http://dx.doi.org/10.1002/cbic.201000372DOI Listing
November 2010

Identification of a heparin binding peptide from the Japanese encephalitis virus envelope protein.

Biopolymers 2010 ;94(3):331-8

Institute of Biotechnology, Department of Life Science, National Tsing Hua University, Hsinchu 300, Taiwan, China.

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http://doi.wiley.com/10.1002/bip.21371
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http://dx.doi.org/10.1002/bip.21371DOI Listing
June 2010

Increased potency of a novel D-beta-naphthylalanine-substituted antimicrobial peptide against fluconazole-resistant fungal pathogens.

FEMS Yeast Res 2009 Sep 21;9(6):967-70. Epub 2009 May 21.

Division of Infectious Diseases, National Health Research Institutes, Miaoli, Taiwan.

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http://dx.doi.org/10.1111/j.1567-1364.2009.00531.xDOI Listing
September 2009

A new protocol for high-yield purification of recombinant human CXCL8((3-72))K11R/G31P expressed in Escherichia coli.

Protein Expr Purif 2008 Sep 1;61(1):65-72. Epub 2008 May 1.

Institute of Biotechnology, Department of Life Science, National Tsing Hua University, Hsinchu 300, Taiwan.

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http://dx.doi.org/10.1016/j.pep.2008.04.007DOI Listing
September 2008

Triggering vacuum capillaries for pneumatic pumping and metering liquids in point-of-care immunoassays.

Lab Chip 2008 Jul 16;8(7):1216-9. Epub 2008 May 16.

Institute of Biotechnology and Department of Life Science, National Tsing Hua University, Hsinchu 300, Taiwan.

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http://dx.doi.org/10.1039/b801878bDOI Listing
July 2008

Solution structure of a novel D-naphthylalanine substituted peptide with potential antibacterial and antifungal activities.

Biopolymers 2007 ;88(5):738-45

Institute of Biotechnology and Department of Life Science, National Tsing Hua University, Hsinchu 300, Taiwan.

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http://dx.doi.org/10.1002/bip.20736DOI Listing
February 2008

Solution structure and neutralizing antibody binding studies of domain III of the dengue-2 virus envelope protein.

Proteins 2008 Feb;70(3):1116-9

Institute of Biotechnology and Department of Life Science, National Tsing Hua University, Hsinchu 300, Taiwan.

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http://dx.doi.org/10.1002/prot.21806DOI Listing
February 2008

Solution structure and phosphopeptide binding of the SH2 domain from the human Bruton's tyrosine kinase.

J Biomol NMR 2006 Sep 13;36(1):73-8. Epub 2006 Sep 13.

Institute of Biotechnology and Department of Life Science, National Tsing Hua University, Hsinchu, Taiwan, ROC.

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http://dx.doi.org/10.1007/s10858-006-9064-3DOI Listing
September 2006

Solution structure of a novel tryptophan-rich peptide with bidirectional antimicrobial activity.

J Bacteriol 2006 Jan;188(1):328-34

Pacgen Biopharmaceuticals Corp., 1730-505 Burrard Street, Vancouver, BC V7X 1M6, Canada.

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http://dx.doi.org/10.1128/JB.188.1.328-334.2006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1317575PMC
January 2006

Structural basis of a flavivirus recognized by its neutralizing antibody: solution structure of the domain III of the Japanese encephalitis virus envelope protein.

J Biol Chem 2003 Nov 2;278(46):46007-13. Epub 2003 Sep 2.

Institute of Biotechnology and Department of Life Science, National Tsing Hua University, Hsinchu, Taiwan 300, Republic of China.

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http://dx.doi.org/10.1074/jbc.M307776200DOI Listing
November 2003