Publications by authors named "Justus Duyster"

100Publications

Prevalence and characteristics of myeloproliferative neoplasms with concomitant monoclonal gammopathy.

Leuk Res 2020 11 15;98:106454. Epub 2020 Sep 15.

Department of Medicine I, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Germany; German Cancer Consortium (DKTK) Partner Site, Freiburg, Germany. Electronic address:

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November 2020

Covid-19 in patients with hematological and solid cancers at a Comprehensive Cancer Center in Germany.

Cancer Med 2020 11 15;9(22):8412-8422. Epub 2020 Sep 15.

Department of Medicine I, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Germany.

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November 2020

Development and Clinical Validation of Discriminatory Multitarget Digital Droplet PCR Assays for the Detection of Hot Spot KRAS and NRAS Mutations in Cell-Free DNA.

J Mol Diagn 2020 07 4;22(7):943-956. Epub 2020 May 4.

Department of Medicine I (Hematology, Oncology and Stem Cell Transplantation), Freiburg University Medical Center, Freiburg, Germany; German Cancer Consortium (DKTK) partner site Freiburg, Heidelberg, Germany; Department of Medical Oncology and Hematology, Zurich University Hospital, Zurich, Switzerland. Electronic address:

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July 2020

CCL5 mediates target-kinase independent resistance to FLT3 inhibitors in FLT3-ITD-positive AML.

Mol Oncol 2020 04 13;14(4):779-794. Epub 2020 Feb 13.

Department of Medicine I (Hematology, Oncology and Stem Cell Transplantation), Medical Center, Faculty of Medicine, University of Freiburg, Germany.

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April 2020

Proteomic Phosphosite Analysis Identified Crucial NPM-ALK-Mediated NIPA Serine and Threonine Residues.

Int J Mol Sci 2019 Aug 20;20(16). Epub 2019 Aug 20.

Department of Hematology and Oncology, Freiburg University Medical Center, Albert-Ludwigs-University of Freiburg, 79106 Freiburg, Germany.

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August 2019

Phenotypical and functional analysis of donor lymphocyte infusion products after long-term cryopreservation.

Transfus Apher Sci 2020 Feb 10;59(1):102594. Epub 2019 Jul 10.

Department of Hematology, Oncology and Stem Cell Transplantation, University of Freiburg, Faculty of Medicine, Freiburg, Germany.

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February 2020

Avoiding chemotherapy prescribing errors: Analysis and innovative strategies.

Cancer 2019 05 29;125(9):1547-1557. Epub 2019 Jan 29.

Department of Hematology, Oncology, and Stem Cell Transplantation, Faculty of Medicine, University of Freiburg, Freiburg, Germany.

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May 2019

Droplet digital PCR for the simultaneous analysis of minimal residual disease and hematopoietic chimerism after allogeneic cell transplantation.

Clin Chem Lab Med 2019 04;57(5):641-647

Department of Hematology, Oncology and Stem Cell Transplantation, University of Freiburg, Faculty of Medicine, Freiburg, Germany.

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April 2019

APC/C regulates the balance between maintenance and differentiation of hematopoietic stem and progenitor cells.

Cell Mol Life Sci 2019 Jan 24;76(2):369-380. Epub 2018 Oct 24.

Department of Hematology, Oncology and Stem Cell Transplantation, Medical Center, University of Freiburg, Faculty of Medicine, Hugstetter Strasse 55, 79106, Freiburg, Germany.

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January 2019

Current Immunotherapeutic Approaches in T Cell Non-Hodgkin Lymphomas.

Cancers (Basel) 2018 Sep 18;10(9). Epub 2018 Sep 18.

Department of Hematology and Oncology, Medical Center, Faculty of Medicine, University of Freiburg, 79106 Freiburg, Germany.

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September 2018

Decitabine in combination with donor lymphocyte infusions can induce remissions in relapsed myeloid malignancies with higher leukemic burden after allogeneic hematopoietic cell transplantation.

Leuk Res 2018 09 7;72:20-26. Epub 2018 Jul 7.

Department of Hematology, Oncology and Stem Cell Transplantation, University of Freiburg Medical Center, Freiburg, Germany; German Cancer Consortium (DKTK), Freiburg, Germany; German Cancer Research Center (DKFZ), Heidelberg, Germany. Electronic address:

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September 2018

Erratum: Sorafenib promotes graft-versus-leukemia activity in mice and humans through IL-15 production in FLT3-ITD-mutant leukemia cells.

Authors:
Nimitha R Mathew Francis Baumgartner Lukas Braun David O'Sullivan Simone Thomas Miguel Waterhouse Tony A Müller Kathrin Hanke Sanaz Taromi Petya Apostolova Anna L Illert Wolfgang Melchinger Sandra Duquesne Annette Schmitt-Graeff Lena Osswald Kai-Li Yan Arnim Weber Sonia Tugues Sabine Spath Dietmar Pfeifer Marie Follo Rainer Claus Michael Lübbert Christoph Rummelt Hartmut Bertz Ralph Wäsch Johanna Haag Andrea Schmidts Michael Schultheiss Dominik Bettinger Robert Thimme Evelyn Ullrich Yakup Tanriver Giang Lam Vuong Renate Arnold Philipp Hemmati Dominik Wolf Markus Ditschkowski Cordula Jilg Konrad Wilhelm Christian Leiber Sabine Gerull Jörg Halter Claudia Lengerke Thomas Pabst Thomas Schroeder Guido Kobbe Wolf Rösler Soroush Doostkam Stephan Meckel Kathleen Stabla Stephan K Metzelder Sebastian Halbach Tilman Brummer Zehan Hu Joern Dengjel Björn Hackanson Christoph Schmid Udo Holtick Christof Scheid Alexandros Spyridonidis Friedrich Stölzel Rainer Ordemann Lutz P Müller Flore Sicre-de-Fontbrune Gabriele Ihorst Jürgen Kuball Jan E Ehlert Daniel Feger Eva-Maria Wagner Jean-Yves Cahn Jacqueline Schnell Florian Kuchenbauer Donald Bunjes Ronjon Chakraverty Simon Richardson Saar Gill Nicolaus Kröger Francis Ayuk Luca Vago Fabio Ciceri Antonia M Müller Takeshi Kondo Takanori Teshima Susan Klaeger Bernhard Kuster Dennis Dong Hwan Kim Daniel Weisdorf Walter van der Velden Daniela Dörfel Wolfgang Bethge Inken Hilgendorf Andreas Hochhaus Geoffroy Andrieux Melanie Börries Hauke Busch John Magenau Pavan Reddy Myriam Labopin Joseph H Antin Andrea S Henden Geoffrey R Hill Glen A Kennedy Merav Bar Anita Sarma Donal McLornan Ghulam Mufti Betul Oran Katayoun Rezvani Omid Shah Robert S Negrin Arnon Nagler Marco Prinz Andreas Burchert Andreas Neubauer Dietrich Beelen Andreas Mackensen Nikolas von Bubnoff Wolfgang Herr Burkhard Becher Gerard Socié Michael A Caligiuri Eliana Ruggiero Chiara Bonini Georg Häcker Justus Duyster Jürgen Finke Erika Pearce Bruce R Blazar Robert Zeiser

Nat Med 2018 Apr;24(4):526

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April 2018

Anti-Angiogenics: Current Situation and Future Perspectives.

Oncol Res Treat 2018 23;41(4):166-171. Epub 2018 Mar 23.

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August 2019

Sorafenib promotes graft-versus-leukemia activity in mice and humans through IL-15 production in FLT3-ITD-mutant leukemia cells.

Authors:
Nimitha R Mathew Francis Baumgartner Lukas Braun David O'Sullivan Simone Thomas Miguel Waterhouse Tony A Müller Kathrin Hanke Sanaz Taromi Petya Apostolova Anna L Illert Wolfgang Melchinger Sandra Duquesne Annette Schmitt-Graeff Lena Osswald Kai-Li Yan Arnim Weber Sonia Tugues Sabine Spath Dietmar Pfeifer Marie Follo Rainer Claus Michael Lübbert Christoph Rummelt Hartmut Bertz Ralph Wäsch Johanna Haag Andrea Schmidts Michael Schultheiss Dominik Bettinger Robert Thimme Evelyn Ullrich Yakup Tanriver Giang Lam Vuong Renate Arnold Philipp Hemmati Dominik Wolf Markus Ditschkowski Cordula Jilg Konrad Wilhelm Christian Leiber Sabine Gerull Jörg Halter Claudia Lengerke Thomas Pabst Thomas Schroeder Guido Kobbe Wolf Rösler Soroush Doostkam Stephan Meckel Kathleen Stabla Stephan K Metzelder Sebastian Halbach Tilman Brummer Zehan Hu Joern Dengjel Björn Hackanson Christoph Schmid Udo Holtick Christof Scheid Alexandros Spyridonidis Friedrich Stölzel Rainer Ordemann Lutz P Müller Flore Sicre-de-Fontbrune Gabriele Ihorst Jürgen Kuball Jan E Ehlert Daniel Feger Eva-Maria Wagner Jean-Yves Cahn Jacqueline Schnell Florian Kuchenbauer Donald Bunjes Ronjon Chakraverty Simon Richardson Saar Gill Nicolaus Kröger Francis Ayuk Luca Vago Fabio Ciceri Antonia M Müller Takeshi Kondo Takanori Teshima Susan Klaeger Bernhard Kuster Dennis Dong Hwan Kim Daniel Weisdorf Walter van der Velden Daniela Dörfel Wolfgang Bethge Inken Hilgendorf Andreas Hochhaus Geoffroy Andrieux Melanie Börries Hauke Busch John Magenau Pavan Reddy Myriam Labopin Joseph H Antin Andrea S Henden Geoffrey R Hill Glen A Kennedy Merav Bar Anita Sarma Donal McLornan Ghulam Mufti Betul Oran Katayoun Rezvani Omid Shah Robert S Negrin Arnon Nagler Marco Prinz Andreas Burchert Andreas Neubauer Dietrich Beelen Andreas Mackensen Nikolas von Bubnoff Wolfgang Herr Burkhard Becher Gerard Socié Michael A Caligiuri Eliana Ruggiero Chiara Bonini Georg Häcker Justus Duyster Jürgen Finke Erika Pearce Bruce R Blazar Robert Zeiser

Nat Med 2018 03 12;24(3):282-291. Epub 2018 Feb 12.

Department of Hematology, Oncology and Stem Cell Transplantation, Faculty of Medicine, University Medical Center Freiburg, University of Freiburg, Freiburg, Germany.

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March 2018

Cell-free DNA characteristics and chimerism analysis in patients after allogeneic cell transplantation.

Clin Biochem 2018 Feb 24;52:137-141. Epub 2017 Nov 24.

Department of Hematology, Oncology and Stem Cell Transplantation, University of Freiburg, Faculty of Medicine, Freiburg, Germany.

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February 2018

The oligodendrocyte lineage transcription factor 2 (OLIG2) is epigenetically regulated in acute myeloid leukemia.

Exp Hematol 2017 11 28;55:76-85.e3. Epub 2017 Jul 28.

Department of Hematology/Oncology and Stem Cell Transplantation, University Medical Center, Freiburg, Germany; Department of Hematology/Oncology, Medical Center Augsburg, Augsburg, Germany. Electronic address:

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November 2017

CXCL12 and CXCR7 are relevant targets to reverse cell adhesion-mediated drug resistance in multiple myeloma.

Br J Haematol 2017 10 2;179(1):36-49. Epub 2017 Jul 2.

Department of Haematology, Oncology and Stem Cell Transplantation, Faculty of Medicine, University of Freiburg, Freiburg, Germany.

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October 2017

Computational analysis of ABL kinase mutations allows predicting drug sensitivity against selective kinase inhibitors.

Tumour Biol 2017 May;39(5):1010428317701643

1 Molecular Medicine and Therapeutics Laboratory, Centre for Plant Molecular Biology (CPMB), Osmania University, Hyderabad, India.

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May 2017

Proteasome inhibition enhances the efficacy of volasertib-induced mitotic arrest in AML in vitro and prolongs survival in vivo.

Oncotarget 2017 Mar;8(13):21153-21166

Department of Hematology, Oncology and Stem Cell Transplantation, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.

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March 2017

Successful peripheral blood stem cell mobilization with a cost-efficient single fixed-dose plerixafor schedule in poor mobilizers.

Leuk Lymphoma 2017 08 13;58(8):1849-1858. Epub 2017 Jan 13.

a Department of Hematology , Oncology and Stem Cell Transplantation, Medical Center, Faculty of Medicine, University of Freiburg , Freiburg , Germany.

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August 2017

Suppression of APC/CCdh1 has subtype specific biological effects in acute myeloid leukemia.

Oncotarget 2016 Jul;7(30):48220-48230

Department of Hematology, Oncology and Stem Cell Transplantation, University Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany.

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July 2016

Sensitive and accurate quantification of JAK2 V617F mutation in chronic myeloproliferative neoplasms by droplet digital PCR.

Ann Hematol 2016 Apr 1;95(5):739-44. Epub 2016 Mar 1.

Department of Hematology, Oncology and Stem Cell Transplantation, University Medical Center Freiburg, Hugstetter Str. 55, 79106, Freiburg, Germany.

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April 2016

From CLL to Multiple Myeloma - Spleen Tyrosine Kinase (SYK) influences multiple myeloma cell survival and migration.

Br J Haematol 2016 09 22;174(6):985-9. Epub 2015 Oct 22.

Department of Haematology, Oncology and Stem Cell Transplantation, University Medical Centre Freiburg, Freiburg, Germany.

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September 2016

MicroRNA-155-deficient dendritic cells cause less severe GVHD through reduced migration and defective inflammasome activation.

Blood 2015 Jul 13;126(1):103-12. Epub 2015 May 13.

Department of Hematology and Oncology, Freiburg University Medical Center, Centre for Biological Signalling Studies BIOSS, Albert-Ludwigs-University, Freiburg, Germany.

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July 2015

MiR-146a regulates the TRAF6/TNF-axis in donor T cells during GVHD.

Blood 2014 Oct 9;124(16):2586-95. Epub 2014 Sep 9.

Department of Hematology, Oncology and Stem Cell Transplantation, Freiburg University Medical Center, Centre for Biological Signaling Studies, Albert Ludwigs University Freiburg, Freiburg, Germany.

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October 2014

Targeting oncoprotein stability overcomes drug resistance caused by FLT3 kinase domain mutations.

PLoS One 2014 21;9(5):e97116. Epub 2014 May 21.

Department Medicine I, University Medical Center Freiburg, Freiburg, Germany.

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June 2015

Successful vemurafenib salvage treatment in a patient with primary refractory hairy cell leukemia and pulmonary aspergillosis.

Ann Hematol 2014 Aug 14;93(8):1439-40. Epub 2013 Dec 14.

Department of Hematology and Oncology, University of Freiburg Medical Center, Hugstetter Straße 55, 79106, Freiburg, Germany,

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August 2014

Analysis of conformational determinants underlying HSP90-kinase interaction.

PLoS One 2013 2;8(7):e68394. Epub 2013 Jul 2.

Department Medicine I, University Medical Center Freiburg, Freiburg, Germany.

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February 2014

Asymmetric kinase dimer formation is crucial for the activation of oncogenic EGFRvIII but not for ERBB3 phosphorylation.

Cell Commun Signal 2013 Jun 10;11:39. Epub 2013 Jun 10.

Department Medicine I, University Medical Center Freiburg, Freiburg, Germany.

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June 2013

Sequential inhibitor therapy in CML: in vitro simulation elucidates the pattern of resistance mutations after second- and third-line treatment.

Clin Cancer Res 2013 Jun 2;19(11):2962-72. Epub 2013 Apr 2.

III. Medizinische Klinik und Poliklinik, Klinikum rechts der Isar, Technische Universität München, München, Germany.

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June 2013

SRC is a signaling mediator in FLT3-ITD- but not in FLT3-TKD-positive AML.

Blood 2012 Apr 12;119(17):4026-33. Epub 2012 Mar 12.

Department of Internal Medicine III, Klinikum rechts der Isar, Technical University of Munich, Ismaningerstrasse 22, Munich, Germany.

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April 2012