Justo Lorenzo Bermejo

Justo Lorenzo Bermejo

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Justo Lorenzo Bermejo

Justo Lorenzo Bermejo

Publications by authors named "Justo Lorenzo Bermejo"

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100Publications

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Data mining and machine learning approaches for the integration of genome-wide association and methylation data: methodology and main conclusions from GAW20.

BMC Genet 2018 Sep 17;19(Suppl 1):76. Epub 2018 Sep 17.

Institute of Medical Biometry and Informatics, University of Heidelberg, Im Neuenheimer Feld 130.3, 69120, Heidelberg, Germany.

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September 2018

GAW20: methods and strategies for the new frontiers of epigenetics and pharmacogenomics.

BMC Proc 2018 17;12(Suppl 9):26. Epub 2018 Sep 17.

12Department of Genetics, Perelman School of Medicine, University of Pennsylvania, 3400 Civic Center Blvd., Philadelphia, PA 19104 USA.

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September 2018

A comparative analysis of cell-type adjustment methods for epigenome-wide association studies based on simulated and real data sets.

Brief Bioinform 2018 Aug 6. Epub 2018 Aug 6.

Statistical Genetics Group, Institute of Medical Biometry and Informatics, University of Heidelberg, Germany.

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August 2018

Gene Expression Profiling in Abdominal Aortic Aneurysms After Finite Element Rupture Risk Assessment.

J Endovasc Ther 2017 Dec 31;24(6):861-869. Epub 2017 Aug 31.

1 Department of Vascular and Endovascular Surgery, Universitätsklinikum Heidelberg, Germany.

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December 2017

Treatment with insulin analogs and prevalence of cardiovascular complications in patients with type 1 diabetes.

Ther Adv Endocrinol Metab 2017 Nov 10;8(11):149-157. Epub 2017 Oct 10.

Institute of Medical Biometry and Informatics, Germany.

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November 2017

Effect of prosthetic restoration on implant survival and success.

Clin Oral Implants Res 2017 Oct 13;28(10):1296-1302. Epub 2016 Sep 13.

Department of Prosthodontics, University Hospital Heidelberg, Heidelberg, Germany.

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October 2017

Imputation of missing genotypes within LD-blocks relying on the basic coalescent and beyond: consideration of population growth and structure.

BMC Genomics 2017 Oct 17;18(1):798. Epub 2017 Oct 17.

Institute of Medical Biometry and Informatics, University of Heidelberg, 69120, Heidelberg, Germany.

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October 2017

Application of the lymphocyte Cytokinesis-Block Micronucleus Assay to populations exposed to petroleum and its derivatives: Results from a systematic review and meta-analysis.

Mutat Res 2016 Oct - Dec;770(Pt A):58-72. Epub 2016 Mar 4.

Department of Pharmacy and Biotechnology, Via Irnerio 48, I-40126, University of Bologna, Bologna, Italy.

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May 2017

Using next-generation DNA sequence data for genetic association tests based on allele counts with and without consideration of zero inflation.

BMC Proc 2016 18;10(Suppl 7):397-404. Epub 2016 Oct 18.

Institute of Medical Biometry and Informatics, University of Heidelberg, Heidelberg, 69120 Germany.

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October 2016

Satisfaction with the level and type of resource use of a health insurance scheme in Nigeria: health management organizations' perspectives.

Int J Health Plann Manage 2014 Oct-Dec;29(4):e309-28. Epub 2013 Dec 3.

Institute of Public Health, Medical Faculty, Heidelberg University, Heidelberg, Germany; Ahmadu Bello University, Zaria, Nigeria.

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September 2016

Undetected residual cement on standard or individualized all-ceramic abutments with cemented zirconia single crowns - a prospective randomized pilot trial.

Clin Oral Implants Res 2016 Sep 18;27(9):1065-71. Epub 2015 Sep 18.

Department of Prosthodontics, University of Heidelberg, Heidelberg, Germany.

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September 2016

Treatment with insulin analogs, especially Glargine and Lispro, associates with better renal function and higher hemoglobin levels in Type 1 diabetic patients with impaired kidney function.

Ther Adv Endocrinol Metab 2016 Aug 15;7(4):166-77. Epub 2016 May 15.

Institute of Medical Biometry and Informatics, University of Heidelberg, Germany.

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August 2016

High prevalence and predominance of BRCA1 germline mutations in Pakistani triple-negative breast cancer patients.

BMC Cancer 2016 08 23;16(1):673. Epub 2016 Aug 23.

German Cancer Research Center (DKFZ), Molecular Genetics of Breast Cancer, Heidelberg, Germany.

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August 2016

User experience with a health insurance coverage and benefit-package access: implications for policy implementation towards expansion in Nigeria.

Health Policy Plan 2016 Apr 10;31(3):346-55. Epub 2015 Aug 10.

Institute of Public Health, Medical Faculty, Heidelberg University, Heidelberg, Germany.

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April 2016

Above and beyond state-of-the-art approaches to investigate sequence data: summary of methods and results from the population-based association group at the Genetic Analysis Workshop 19.

BMC Genet 2016 Feb 3;17 Suppl 2. Epub 2016 Feb 3.

Statistical Genetics Group, Institute of Medical Biometry and Informatics, University of Heidelberg, Im Neuenheimer Feld 305, 69120, Heidelberg, Germany.

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February 2016

Neonatal variables, altitude of residence and Aymara ancestry in northern Chile.

PLoS One 2015 17;10(4):e0121834. Epub 2015 Apr 17.

Department of Human Biology, Zoological Institute, Christian Albrechts-University, Kiel, Germany.

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January 2016

Nuclear expression of the deubiquitinase CYLD is associated with improved survival in human hepatocellular carcinoma.

PLoS One 2014 16;9(10):e110591. Epub 2014 Oct 16.

National Center for Tumor Diseases, Department of Medical Oncology, Internal Medicine VI, Heidelberg University Hospital, Heidelberg, Germany; Department of Gastroenterology, Diabetology and Rheumatology, Internal Medicine II, Marien-Hospital, Wesel, Germany.

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December 2015

T-DM1 as a New Treatment Option for Patients with Metastatic HER2-positive Breast Cancer in Clinical Practice.

Anticancer Res 2015 Sep;35(9):5085-90

National Center for Tumor Diseases, University Hospital, Heidelberg, Germany Department of Obstetrics and Gynecology, University Hospital, Heidelberg, Germany.

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September 2015

Sleep-associated aspects of myofascial pain in the orofacial area among Temporomandibular Disorder patients and controls.

Sleep Med 2015 Sep 11;16(9):1056-61. Epub 2015 May 11.

Department of Prosthodontics, University of Heidelberg, Im Neuenheimer Feld 400, 69120 Heidelberg, Germany.

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September 2015

Electroplated and cast double crown-retained removable dental prostheses: 6-year results from a randomized clinical trial.

Clin Oral Investig 2015 Jun 11;19(5):1129-36. Epub 2014 Oct 11.

Department of Prosthodontics, University Hospital Heidelberg, Im Neuenheimer Feld 400, 69120, Heidelberg, Germany,

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June 2015

Alignment of high-throughput sequencing data inside in-memory databases.

Stud Health Technol Inform 2014 ;205:476-80

Institute of Medical Biometry and Informatics, Heidelberg, Germany.

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May 2015

Tailored selection of study individuals to be sequenced in order to improve the accuracy of genotype imputation.

Genet Epidemiol 2015 Feb 23;39(2):114-21. Epub 2014 Dec 23.

Institute of Medical Biometry and Informatics, University of Heidelberg, Heidelberg, Germany.

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February 2015

Inherited variants in the inner centromere protein (INCENP) gene of the chromosomal passenger complex contribute to the susceptibility of ER-negative breast cancer.

Authors:
Maria Kabisch Justo Lorenzo Bermejo Thomas Dünnebier Shibo Ying Kyriaki Michailidou Manjeet K Bolla Qin Wang Joe Dennis Mitul Shah Barbara J Perkins Kamila Czene Hatef Darabi Mikael Eriksson Stig E Bojesen Børge G Nordestgaard Sune F Nielsen Henrik Flyger Diether Lambrechts Patrick Neven Stephanie Peeters Caroline Weltens Fergus J Couch Janet E Olson Xianshu Wang Kristen Purrington Jenny Chang-Claude Anja Rudolph Petra Seibold Dieter Flesch-Janys Julian Peto Isabel dos-Santos-Silva Nichola Johnson Olivia Fletcher Heli Nevanlinna Taru A Muranen Kristiina Aittomäki Carl Blomqvist Marjanka K Schmidt Annegien Broeks Sten Cornelissen Frans B L Hogervorst Jingmei Li Judith S Brand Keith Humphreys Pascal Guénel Thérèse Truong Florence Menegaux Marie Sanchez Barbara Burwinkel Frederik Marmé Rongxi Yang Peter Bugert Anna González-Neira Javier Benitez M Pilar Zamora Jose I Arias Perez Angela Cox Simon S Cross Malcolm W R Reed Irene L Andrulis Julia A Knight Gord Glendon Sandrine Tchatchou Elinor J Sawyer Ian Tomlinson Michael J Kerin Nicola Miller Christopher A Haiman Fredrick Schumacher Brian E Henderson Loic Le Marchand Annika Lindblom Sara Margolin Maartje J Hooning Antoinette Hollestelle Mieke Kriege Linetta B Koppert John L Hopper Melissa C Southey Helen Tsimiklis Carmel Apicella Seth Slettedahl Amanda E Toland Celine Vachon Drakoulis Yannoukakos Graham G Giles Roger L Milne Catriona McLean Peter A Fasching Matthias Ruebner Arif B Ekici Matthias W Beckmann Hermann Brenner Aida K Dieffenbach Volker Arndt Christa Stegmaier Alan Ashworth Nicholas Orr Minouk J Schoemaker Anthony Swerdlow Montserrat García-Closas Jonine Figueroa Stephen J Chanock Jolanta Lissowska Mark S Goldberg France Labrèche Martine Dumont Robert Winqvist Katri Pylkäs Arja Jukkola-Vuorinen Mervi Grip Hiltrud Brauch Thomas Brüning Yon-Dschun Ko Paolo Radice Paolo Peterlongo Giulietta Scuvera Stefano Fortuzzi Natalia Bogdanova Thilo Dörk Arto Mannermaa Vesa Kataja Veli-Matti Kosma Jaana M Hartikainen Peter Devilee Robert A E M Tollenaar Caroline Seynaeve Christi J Van Asperen Anna Jakubowska Jan Lubinski Katarzyna Jaworska-Bieniek Katarzyna Durda Wei Zheng Martha J Shrubsole Qiuyin Cai Diana Torres Hoda Anton-Culver Vessela Kristensen François Bacot Daniel C Tessier Daniel Vincent Craig Luccarini Caroline Baynes Shahana Ahmed Mel Maranian Jacques Simard Georgia Chenevix-Trench Per Hall Paul D P Pharoah Alison M Dunning Douglas F Easton Ute Hamann

Carcinogenesis 2015 Feb 13;36(2):256-71. Epub 2015 Jan 13.

Molecular Genetics of Breast Cancer, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany,

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February 2015

Prognostic significance of spontaneous antibody responses against tumor-associated antigens in malignant melanoma patients.

Int J Cancer 2015 Jan 28;136(1):138-51. Epub 2014 May 28.

Department of Medical Oncology, National Center for Tumor Diseases, Internal Medicine VI, Heidelberg University Hospital, Heidelberg, Germany.

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January 2015

Practical investigation of the performance of robust logistic regression to predict the genetic risk of hypertension.

BMC Proc 2014 17;8(Suppl 1):S65. Epub 2014 Jun 17.

Institute of Medical Biometry and Informatics, University of Heidelberg, Im Neuenheimer Feld 305, 69120 Heidelberg, Germany.

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December 2014

Local and global ancestry inference and applications to genetic association analysis for admixed populations.

Genet Epidemiol 2014 Sep;38 Suppl 1:S5-S12

Department of Biostatistics, University of Washington, Seattle, Washington, United States of America.

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September 2014

Beyond cell death - antiapoptotic Bcl-2 proteins regulate migration and invasion of colorectal cancer cells in vitro.

PLoS One 2013 3;8(10):e76446. Epub 2013 Oct 3.

National Center for Tumor Diseases, Department of Medical Oncology, Internal Medicine VI, Heidelberg University Hospital, Heidelberg, Germany.

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July 2014

Age-time risk patterns of solid cancers in 60 901 non-Hodgkin lymphoma survivors from Finland, Norway and Sweden.

Br J Haematol 2014 Mar 4;164(5):675-83. Epub 2013 Dec 4.

Institute of Medical Biometry and Informatics, University of Heidelberg, Heidelberg, Germany; Division of Molecular Genetic Epidemiology, German Cancer Research Centre (DKFZ), Heidelberg, Germany.

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March 2014

Performance evaluation of a health insurance in Nigeria using optimal resource use: health care providers perspectives.

BMC Health Serv Res 2014 Mar 14;14:127. Epub 2014 Mar 14.

Institute of Public Health, Medical Faculty Heidelberg, Heidelberg University, Im Neuenheimer Feld 324, 69120 Heidelberg, Germany.

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March 2014

CYP3A activity in severe liver cirrhosis correlates with Child-Pugh and model for end-stage liver disease (MELD) scores.

Br J Clin Pharmacol 2014 Jan;77(1):160-9

Department of Clinical Pharmacology and Pharmacoepidemiology, University of Heidelberg, Heidelberg, Germany.

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January 2014

Chromosomal gains and losses in human papillomavirus-associated neoplasia of the lower genital tract - a systematic review and meta-analysis.

Eur J Cancer 2014 Jan 17;50(1):85-98. Epub 2013 Sep 17.

Department of Applied Tumor Biology, Institute of Pathology, University of Heidelberg, Im Neuenheimer Feld 224, 69120 Heidelberg, Germany; Clinical Cooperation Unit, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 224, 69120 Heidelberg, Germany. Electronic address:

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January 2014

The receptor for advanced glycation end products is dispensable in a mouse model of oral and esophageal carcinogenesis.

Histol Histopathol 2013 12 28;28(12):1585-94. Epub 2013 May 28.

Experimental Head and Neck Oncology, Department of Otolaryngology, Head and Neck Surgery, University Hospital Heidelberg, and Division of Signal Transduction and Growth Control (A100), DKFZ-ZMBH Alliance, German Cancer Research Center Heidelberg, Heidelberg, Germany.

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December 2013

Assessing responsiveness of health care services within a health insurance scheme in Nigeria: users' perspectives.

BMC Health Serv Res 2013 Dec 1;13:502. Epub 2013 Dec 1.

Institute of Public Health, Medical Faculty, Heidelberg University, Heidelberg, Germany.

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December 2013

Senescence-associated protein p400 is a prognostic marker in renal cell carcinoma.

Oncol Rep 2013 Nov 26;30(5):2245-53. Epub 2013 Aug 26.

Institute of Pathology, University Hospital of Heidelberg, D-69120 Heidelberg, Germany.

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November 2013

Biological subtypes of triple-negative breast cancer are associated with distinct morphological changes and clinical behaviour.

Breast 2013 Oct 24;22(5):986-92. Epub 2013 Jun 24.

Institute of Pathology, University Hospital Heidelberg, Im Neuenheimer Feld 224, 69120 Heidelberg, Germany.

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October 2013

Whole brain helical Tomotherapy with integrated boost for brain metastases in patients with malignant melanoma-a randomized trial.

Radiat Oncol 2013 Oct 10;8:234. Epub 2013 Oct 10.

Department of Radiation Oncology, University Hospital of Heidelberg, INF 400, 69120, Heidelberg, Germany.

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October 2013

Variants at the 9p21 locus and melanoma risk.

BMC Cancer 2013 Jul 2;13:325. Epub 2013 Jul 2.

Division of Molecular Genetic Epidemiology, German Cancer Research Centre (DKFZ), Im Neuenheimer Feld 580, D-69120, Heidelberg, Germany.

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July 2013

Long-term oncological outcomes after laparoscopic radical prostatectomy.

BJU Int 2013 Feb 3;111(2):271-80. Epub 2012 Jul 3.

Department of Urology, SLK-Kliniken, Heilbronn, Germany.

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February 2013

Variants at chromosome 20 (ASIP locus) and melanoma risk.

Int J Cancer 2013 Jan 13;132(1):42-54. Epub 2012 Jun 13.

Division of Molecular Genetic Epidemiology, German Cancer Research Centre, Heidelberg, Germany.

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January 2013

Treatment outcome of mineral trioxide aggregate in open apex teeth.

J Endod 2013 Jan;39(1):20-6

Division of Endodontics and Dental Traumatology, Department of Conservative Dentistry, Ruprecht-Karls-University, Heidelberg, Germany.

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January 2013

Influence of bone augmentation procedures on the short-term prognosis of simultaneously placed implants.

Clin Oral Implants Res 2012 Oct 29;23(10):1232-7. Epub 2011 Sep 29.

Department of Prosthodontics, University Hospital Heidelberg, Heidelberg, Germany.

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October 2012

Characterization of nonacral melanoma patients without typical risk factors.

Melanoma Res 2012 Aug;22(4):316-9

Department of Dermatology, Instituto Valenciano de Oncologia, Universidad Católica de Valencia, Valencia, Spain.

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August 2012

Random forest Gini importance favours SNPs with large minor allele frequency: impact, sources and recommendations.

Brief Bioinform 2012 May 10;13(3):292-304. Epub 2011 Sep 10.

Department of Medical Informatics, Biometry and Epidemiology, University of Munich, Marchioninistr. 15, 81377 Munich, Germany.

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May 2012

Comparison of six statistics of genetic association regarding their ability to discriminate between causal variants and genetically linked markers.

Hum Hered 2011 19;72(2):142-52. Epub 2011 Oct 19.

Institute of Medical Biometry and Informatics, University Hospital Heidelberg, Germany. Justo.Lorenzo @ imbi.uni-heidelberg.de

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February 2012

Systems-wide proteomic analysis in mammalian cells reveals conserved, functional protein turnover.

J Proteome Res 2011 Dec 3;10(12):5275-84. Epub 2011 Nov 3.

Max-Planck-Institute for Biochemistry, Am Klopferspitz 18, 82152 Munich-Martinsried, Germany.

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December 2011

Using the posterior distribution of deviance to measure evidence of association for rare susceptibility variants.

BMC Proc 2011 Nov 29;5 Suppl 9:S38. Epub 2011 Nov 29.

Institute of Medical Biometry and Informatics, University Hospital Heidelberg, INF 305, 69120 Heidelberg, Germany.

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November 2011

7q21-rs6964587 and breast cancer risk: an extended case-control study by the Breast Cancer Association Consortium.

J Med Genet 2011 Oct;48(10):698-702

Genetic and Molecular Epidemiology Group, Human Cancer Genetics Program, Spanish National Cancer Research Centre, CNIO, Calle Melchor Fernández Almagro 3, 28039 Madrid, Spain.

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October 2011

Expression of nuclear receptor corepressors and class I histone deacetylases in astrocytic gliomas.

Cancer Sci 2011 Feb 10;102(2):387-92. Epub 2010 Dec 10.

Division of Neurosurgical Research, Department of Neurosurgery, University of Heidelberg, Heidelberg, Germany.

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February 2011

Clustering of concordant and discordant cancer types in Swedish couples is rare.

Eur J Cancer 2011 Jan 23;47(1):98-106. Epub 2010 Jul 23.

Division of Molecular Genetic Epidemiology, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 580, 69120 Heidelberg, Germany.

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January 2011

Genotypes, haplotypes and diplotypes of three XPC polymorphisms in urinary-bladder cancer patients.

Mutat Res 2010 Dec 29;694(1-2):39-44. Epub 2010 Sep 29.

Urologylab, Dept. Molecular Medicine and Surgery, Karolinska Institute and Department of Urology, Karolinska Hospital, Stockholm, Sweden.

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December 2010

Tumor location and patient characteristics of colon and rectal adenocarcinomas in relation to survival and TNM classes.

BMC Cancer 2010 Dec 21;10:688. Epub 2010 Dec 21.

Division of Molecular Genetic Epidemiology, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 580, D-69120 Heidelberg, Germany.

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December 2010

Age-specific risk of incident prostate cancer and risk of death from prostate cancer defined by the number of affected family members.

Eur Urol 2010 Aug 13;58(2):275-80. Epub 2010 Feb 13.

Division of Molecular Genetic Epidemiology, German Cancer Research Centre (DKFZ), Im Neuenheimer Feld 580, Heidelberg, Germany.

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August 2010

Re: "underlying genetic models of inheritance in established type 2 diabetes associations".

Am J Epidemiol 2010 May 13;171(10):1153-4; author reply 1154-5. Epub 2010 Apr 13.

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May 2010

Familial risks of breast and prostate cancers: does the definition of the at risk period matter?

Eur J Cancer 2010 Mar;46(4):752-7

Division of Molecular Genetic Epidemiology, German Cancer Research Centre (DKFZ), 69120 Heidelberg, Germany.

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March 2010