Publications by authors named "Justin Stebbing"

100Publications

Clinical Characteristics and Outcomes of COVID-19-Infected Cancer Patients: A Systematic Review and Meta-Analysis.

J Natl Cancer Inst 2020 Nov 2. Epub 2020 Nov 2.

Laura and Isaac Perlmutter Cancer Center, New York University Langone Medical Center, New York, NY, USA.

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http://dx.doi.org/10.1093/jnci/djaa168DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7665647PMC
November 2020

COVID-19 and the risk to cancer patients in China.

Int J Cancer 2020 Oct 2. Epub 2020 Oct 2.

Imperial College, Imperial College NHS Trust, Charing Cross Hospital, London, UK.

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http://dx.doi.org/10.1002/ijc.33325DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7537293PMC
October 2020

A meta-analysis comparing responses of Asian versus non-Asian cancer patients to PD-1 and PD-L1 inhibitor-based therapy.

Oncoimmunology 2020 Jun 26;9(1):1781333. Epub 2020 Jun 26.

Department of Urology, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.

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http://dx.doi.org/10.1080/2162402X.2020.1781333DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7458616PMC
June 2020

The Emergence of Baricitinib: A Story of Tortoises Versus Hares.

Clin Infect Dis 2020 Jul 6. Epub 2020 Jul 6.

Department of Surgery and Cancer, Imperial College, London, United Kingdom.

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http://dx.doi.org/10.1093/cid/ciaa940DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7499511PMC
July 2020

What Is the Best Drug to Treat COVID-19? The Need for Randomized Controlled Trials.

Med (N Y) 2020 May 19. Epub 2020 May 19.

Department of Surgery and Cancer, Imperial College, London W12 0NN, UK.

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http://dx.doi.org/10.1016/j.medj.2020.04.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7235589PMC
May 2020

A cell-cycle signature classifier for pan-cancer analysis.

Oncogene 2020 09 20;39(38):6041-6042. Epub 2020 Aug 20.

Department of Surgery and Cancer, Imperial College, London, UK.

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http://dx.doi.org/10.1038/s41388-020-01426-5DOI Listing
September 2020

Reply to letter to the editor: baricitinib and toxicity is a rare occurrence.

Expert Opin Drug Saf 2020 Oct 24;19(10):1371-1372. Epub 2020 Aug 24.

State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, the First Affiliated Hospital, School of Medicine, Zhejiang University , Hangzhou, Zhejiang, China.

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http://dx.doi.org/10.1080/14740338.2020.1812192DOI Listing
October 2020

A real-world disproportionality analysis of FDA Adverse Event Reporting System (FAERS) events for baricitinib.

Expert Opin Drug Saf 2020 Nov 31;19(11):1505-1511. Epub 2020 Jul 31.

State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, the First Affiliated Hospital, School of Medicine, Zhejiang University , Hangzhou, Zhejiang, China.

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http://dx.doi.org/10.1080/14740338.2020.1799975DOI Listing
November 2020

Is asthma protective against COVID-19?

Allergy 2020 Jun 1. Epub 2020 Jun 1.

SOS Allergy and Clinical Immunology, USL Toscana Centro, Prato, Italy.

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http://dx.doi.org/10.1111/all.14426DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7300712PMC
June 2020

Lessons to Europe from China for cancer treatment during the COVID-19 pandemic.

Br J Cancer 2020 07 14;123(1):7-8. Epub 2020 May 14.

Division of Cancer, Department of Surgery and Cancer, Imperial College London, London, UK.

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http://dx.doi.org/10.1038/s41416-020-0856-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7221334PMC
July 2020

CNS penetration of potential anti-COVID-19 drugs.

J Neurol 2020 Jul 2;267(7):1880-1882. Epub 2020 May 2.

III Division of Infectious Diseases, ASST Fatebenefratelli-Sacco, Milan, Italy.

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http://dx.doi.org/10.1007/s00415-020-09866-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7195609PMC
July 2020

Managing patients with cancer in the COVID-19 era.

Eur J Cancer 2020 06 11;132:5-7. Epub 2020 Apr 11.

Division of Cancer, Department of Surgery and Cancer, Imperial College London, London, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.ejca.2020.03.028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7151313PMC
June 2020

Baricitinib for COVID-19: a suitable treatment? - Authors' reply.

Lancet Infect Dis 2020 09 3;20(9):1013-1014. Epub 2020 Apr 3.

Department of Surgery and Cancer, Imperial College, London W12 0NN, UK. Electronic address:

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http://dx.doi.org/10.1016/S1473-3099(20)30270-XDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7271155PMC
September 2020

The Use of Transdermal Estrogen in Castrate-resistant, Steroid-refractory Prostate Cancer.

Clin Genitourin Cancer 2020 06 10;18(3):e217-e223. Epub 2019 Oct 10.

Barts Cancer Institute, Saint Bartholomew's Hospital, London, UK. Electronic address:

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http://dx.doi.org/10.1016/j.clgc.2019.09.019DOI Listing
June 2020

Understanding the Role of Comparative Clinical Studies in the Development of Oncology Biosimilars.

J Clin Oncol 2020 Apr 14;38(10):1070-1080. Epub 2020 Feb 14.

University of California, San Francisco, Comprehensive Cancer Center, San Francisco, CA.

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http://dx.doi.org/10.1200/JCO.19.02953DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7106981PMC
April 2020

Baricitinib as potential treatment for 2019-nCoV acute respiratory disease.

Lancet 2020 02 4;395(10223):e30-e31. Epub 2020 Feb 4.

Department of Surgery and Cancer, Imperial College London, London SW7 2AZ, UK. Electronic address:

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http://dx.doi.org/10.1016/S0140-6736(20)30304-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7137985PMC
February 2020

Patient-derived xenograft models-the future of personalised cancer treatment.

Br J Cancer 2020 03 10;122(5):601-602. Epub 2020 Jan 10.

Department of Oncology, Charing Cross Hospital, Imperial College and Imperial College Healthcare NHS Trust, Fulham Palace Road, London, W6 8RF, UK.

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http://dx.doi.org/10.1038/s41416-019-0678-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7054515PMC
March 2020

Clinical development of CT-P6 in HER2 positive breast cancer.

Expert Opin Biol Ther 2019 10 11;19(10):987-992. Epub 2019 Sep 11.

Division of Hematology/Oncology, Perlmutter Cancer Center at NYU Langone Health , New York, USA.

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http://dx.doi.org/10.1080/14712598.2019.1665019DOI Listing
October 2019

Endocrine Resistance in Hormone Receptor Positive Breast Cancer-From Mechanism to Therapy.

Front Endocrinol (Lausanne) 2019 24;10:245. Epub 2019 May 24.

School of Life Sciences, University of Westminster, London, United Kingdom.

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http://dx.doi.org/10.3389/fendo.2019.00245DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6543000PMC
May 2019

Decoding Metastatic Colorectal Cancer to Improve Clinical Decision Making.

J Clin Oncol 2019 08 7;37(22):1847-1850. Epub 2019 Jun 7.

1Imperial College, London, United Kingdom.

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http://dx.doi.org/10.1200/JCO.19.01185DOI Listing
August 2019

SSB1/SSB2 Proteins Safeguard B Cell Development by Protecting the Genomes of B Cell Precursors.

J Immunol 2019 06 13;202(12):3423-3433. Epub 2019 May 13.

Centre for Hematology, Department of Medicine, Imperial College London, W12 0NN London, United Kingdom; and

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http://dx.doi.org/10.4049/jimmunol.1801618DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6545462PMC
June 2019

Human NK Cells Develop an Exhaustion Phenotype During Polar Degranulation at the Hyphal Synapse.

Front Immunol 2018 22;9:2344. Epub 2018 Oct 22.

Faculty of Medicine, Imperial College London, National Heart and Lung Institute, London, United Kingdom.

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https://www.frontiersin.org/article/10.3389/fimmu.2018.02344
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http://dx.doi.org/10.3389/fimmu.2018.02344DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6204393PMC
October 2019

Percutaneous irreversible electroporation with systemic treatment for locally advanced pancreatic adenocarcinoma.

J Gastrointest Oncol 2018 Apr;9(2):275-281

Department of Cancer Medicine, Hammersmith Hospital, Imperial College Healthcare NHS Trust, Du Cane Road, London, UK.

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http://dx.doi.org/10.21037/jgo.2018.01.14DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5934146PMC
April 2018

Nivolumab-induced fulminant diabetic ketoacidosis followed by thyroiditis.

Endocrinol Diabetes Metab Case Rep 2018 21;2018. Epub 2018 Mar 21.

Department of Surgery and Cancer, Imperial College London, London, UK.

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http://dx.doi.org/10.1530/EDM-18-0111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5863245PMC
March 2018

Novel putative drivers revealed by targeted exome sequencing of advanced solid tumors.

PLoS One 2018 23;13(3):e0194790. Epub 2018 Mar 23.

Stanley S. Scott Cancer Center, Louisiana State University Health Sciences Center, New Orleans, Louisiana, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0194790PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5865730PMC
July 2018

LMTK3 confers chemo-resistance in breast cancer.

Oncogene 2018 06 15;37(23):3113-3130. Epub 2018 Mar 15.

School of Life Sciences, Department of Biochemistry and Biomedicine, University of Sussex, Brighton, BN1 9QG, UK.

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http://dx.doi.org/10.1038/s41388-018-0197-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992129PMC
June 2018

Efficacy and safety of the trastuzumab biosimilar candidate CT-P6.

Future Oncol 2018 Aug 27;14(19):1909-1919. Epub 2018 Feb 27.

Department of Cancer Medicine and Medical Oncology, Imperial College & Imperial College Healthcare NHS Trust, London, UK.

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https://www.futuremedicine.com/doi/10.2217/fon-2017-0679
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http://dx.doi.org/10.2217/fon-2017-0679DOI Listing
August 2018

Targeted cancer therapies: Oral health care implications.

J Am Dent Assoc 2018 Feb;149(2):100-111

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http://dx.doi.org/10.1016/j.adaj.2017.08.046DOI Listing
February 2018

Harms of cigarette smoking: call to increase knowledge among children.

Eur J Cancer Prev 2019 01;28(1):54-57

Department of Oncology, Imperial College London.

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http://dx.doi.org/10.1097/CEJ.0000000000000409DOI Listing
January 2019

A randomised trial comparing the pharmacokinetics and safety of the biosimilar CT-P6 with reference trastuzumab.

Cancer Chemother Pharmacol 2018 03 12;81(3):505-514. Epub 2018 Jan 12.

CELLTRION Inc, 23 Academy-ro, Yeonsu-gu, Incheon, 22014, Republic of Korea.

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http://dx.doi.org/10.1007/s00280-017-3510-7DOI Listing
March 2018

Geographic Variation in EGFR Mutation Frequency in Lung Adenocarcinoma May Be Explained by Interethnic Genetic Variation.

J Thorac Oncol 2018 03 13;13(3):454-458. Epub 2017 Dec 13.

Imperial College, Imperial Centre for Translational and Experimental Medicine, Hammersmith Hospital, London, United Kingdom; Imperial College Health Care National Health Service Trust, Charing Cross Hospital, London, United Kingdom.

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http://dx.doi.org/10.1016/j.jtho.2017.11.128DOI Listing
March 2018

Liquorice: a treatment for all sorts?

Lancet Oncol 2017 09;18(9):1155

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http://dx.doi.org/10.1016/S1470-2045(17)30628-9DOI Listing
September 2017

The Tumor-Suppressor Protein OPCML Potentiates Anti-EGFR- and Anti-HER2-Targeted Therapy in HER2-Positive Ovarian and Breast Cancer.

Mol Cancer Ther 2017 10 3;16(10):2246-2256. Epub 2017 Aug 3.

Ovarian Cancer Action Research Centre, Department of Surgery and Cancer, Imperial College London, London, United Kingdom.

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http://dx.doi.org/10.1158/1535-7163.MCT-17-0081DOI Listing
October 2017

Chilli-too hot to handle?

Lancet Oncol 2017 08 26;18(8):1005. Epub 2017 Jul 26.

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http://dx.doi.org/10.1016/S1470-2045(17)30522-3DOI Listing
August 2017

Fasting: starving cancer.

Lancet Oncol 2017 04;18(4):431

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http://dx.doi.org/10.1016/S1470-2045(17)30196-1DOI Listing
April 2017

The relationship between ethnicity, social deprivation and late presentation of colorectal cancer.

Cancer Epidemiol 2017 04 4;47:88-93. Epub 2017 Feb 4.

Surgical Epidemiology, Trials and Outcome Centre (SETOC), St Mark's Hospital & Academic Institute, Harrow, Middlesex, HA1 3UJ, United Kingdom; Department of Surgery and Cancer, Imperial College, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.canep.2017.01.007DOI Listing
April 2017

Sustained expression of miR-26a promotes chromosomal instability and tumorigenesis through regulation of CHFR.

Nucleic Acids Res 2017 05;45(8):4401-4412

Department of Surgery and Cancer, Imperial College London, Imperial Centre for Translational and Experimental Medicine (ICTEM), Hammersmith Hospital, London W12 0NN, UK.

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http://dx.doi.org/10.1093/nar/gkx022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5416844PMC
May 2017

Turmeric: a spice for life?

Lancet Oncol 2016 12;17(12):1639

Department of Medical Oncology, Imperial College London W6 8RF, UK. Electronic address:

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http://www.thelancet.com/pdfs/journals/lanonc/PIIS1470-2045(
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http://dx.doi.org/10.1016/S1470-2045(16)30587-3DOI Listing
December 2016

The need for multidisciplinarity in specialist training to optimize future patient care.

Nat Rev Clin Oncol 2017 Aug 29;14(8):508-517. Epub 2016 Nov 29.

NIHR University College London Hospitals Biomedical Research Centre, UCL Cancer Institute, University College London, London WC1E 6DD, UK.

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http://dx.doi.org/10.1038/nrclinonc.2016.185DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7641875PMC
August 2017

Investigating miRNA-mRNA regulatory networks using crosslinking immunoprecipitation methods for biomarker and target discovery in cancer.

Expert Rev Mol Diagn 2016 11 27;16(11):1155-1162. Epub 2016 Oct 27.

a Division of Cancer, Dept. of Surgery & Cancer, Imperial Centre for Translational and Experimental Medicine (ICTEM) , Imperial College , London , UK.

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http://dx.doi.org/10.1080/14737159.2016.1239532DOI Listing
November 2016

Strategies in functional proteomics: Unveiling the pathways to precision oncology.

Cancer Lett 2016 11 2;382(1):86-94. Epub 2016 Feb 2.

Department of Biochemistry and Biomedicine, School of Life Sciences, University of Sussex, Brighton BN1 9QG, UK. Electronic address:

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http://dx.doi.org/10.1016/j.canlet.2016.01.049DOI Listing
November 2016

Garlic: a stake through the heart of cancer?

Lancet Oncol 2016 07;17(7):879-880

Department of Medical Oncology, Imperial College London W6 8RF, UK. Electronic address:

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http://dx.doi.org/10.1016/S1470-2045(16)30235-2DOI Listing
July 2016

MicroRNAs associated with small bowel neuroendocrine tumours and their metastases.

Endocr Relat Cancer 2016 09 27;23(9):711-26. Epub 2016 Jun 27.

Department of Surgery and CancerImperial College, Hammersmith Hospital Campus, London, UK

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http://dx.doi.org/10.1530/ERC-16-0044DOI Listing
September 2016

Corrigendum to "A novel and validated prognostic index in hepatocellular carcinoma: The Inflammation Based Index (IBI)".

J Hepatol 2016 Jun 16. Epub 2016 Jun 16.

Division of Experimental Medicine, Imperial College London, Hammersmith Hospital, Du Cane Road, London, UK. Electronic address:

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http://dx.doi.org/10.1016/j.jhep.2016.05.019DOI Listing
June 2016

Aloe vera, a natural cancer soother?

Lancet Oncol 2016 04 29;17(4):421. Epub 2016 Mar 29.

Imperial College London, London, UK. Electronic address:

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http://dx.doi.org/10.1016/S1470-2045(16)00161-3DOI Listing
April 2016

Proteome-wide dataset supporting functional study of tyrosine kinases in breast cancer.

Data Brief 2016 Jun 14;7:740-6. Epub 2016 Mar 14.

Department of Surgery and Cancer, Imperial College London, Hammersmith Hospital Campus, Du Cane Road, London W12 ONN, UK.

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http://dx.doi.org/10.1016/j.dib.2016.03.024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4804227PMC
June 2016

ATG9A loss confers resistance to trastuzumab via c-Cbl mediated Her2 degradation.

Oncotarget 2016 May;7(19):27599-612

Department of Surgery and Cancer, Division of Cancer, Imperial College London, Hammersmith Hospital Campus, London, UK.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5053674PMC
http://dx.doi.org/10.18632/oncotarget.8504DOI Listing
May 2016

Gene of the month: Axl.

J Clin Pathol 2016 May 7;69(5):391-7. Epub 2016 Mar 7.

Department of Surgery and Cancer, Imperial College London, Hammersmith Hospital Campus, London, UK.

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http://dx.doi.org/10.1136/jclinpath-2016-203629DOI Listing
May 2016

miR-515-5p controls cancer cell migration through MARK4 regulation.

EMBO Rep 2016 04 10;17(4):570-84. Epub 2016 Feb 10.

Department of Surgery & Cancer, Division of Cancer, Imperial Centre for Translational and Experimental Medicine (ICTEM), Imperial College Hammersmith Hospital Campus, London, UK Key Laboratory of Magnetic Resonance in Biological Systems, Wuhan Center for Magnetic Resonance, State Key Laboratory of Magnetic Resonance and Atomic and Molecular Physics, Wuhan Institute of Physics and Mathematics Chinese Academy of Sciences, Wuhan, China

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http://embor.embopress.org/lookup/doi/10.15252/embr.20154097
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http://dx.doi.org/10.15252/embr.201540970DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4818771PMC
April 2016

Melatonin: resetting the clock of cancer progression?

Lancet Oncol 2016 Jan 23;17(1):23-4. Epub 2015 Dec 23.

Imperial College London, London, UK. Electronic address:

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http://dx.doi.org/10.1016/S1470-2045(15)00571-9DOI Listing
January 2016

LMTK3 escapes tumour suppressor miRNAs via sequestration of DDX5.

Cancer Lett 2016 Mar 29;372(1):137-46. Epub 2015 Dec 29.

Department of Surgery and Cancer, Division of Cancer, Imperial College London, Hammersmith Hospital Campus, Du Cane Road, London W12 0NN, UK; Department of Biochemistry and Biomedicine, School of Life Sciences, University of Sussex, Brighton BN1 9QG, UK. Electronic address:

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http://dx.doi.org/10.1016/j.canlet.2015.12.026DOI Listing
March 2016

TP53 regulates miRNA association with AGO2 to remodel the miRNA-mRNA interaction network.

Genome Res 2016 Mar 23;26(3):331-41. Epub 2015 Dec 23.

Department of Surgery and Cancer, Imperial College London, Imperial Centre for Translational and Experimental Medicine, London W12 0NN, United Kingdom;

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http://dx.doi.org/10.1101/gr.191759.115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4772015PMC
March 2016

Single-cell sequencing in cancer research.

Expert Rev Mol Diagn 2016 23;16(1):1-5. Epub 2015 Nov 23.

a Division of Cancer, Department of Surgery & Cancer , Imperial Centre for Translational and Experimental Medicine (ICTEM), Imperial College , Hammersmith Hospital campus, Du Cane Road, London , W12 0NN , UK.

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http://dx.doi.org/10.1586/14737159.2016.1115345DOI Listing
October 2016

Cannabis and cancer: reality or pipe dream?

Lancet Oncol 2015 Oct;16(13):1291-2

Imperial College, London, UK. Electronic address:

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http://dx.doi.org/10.1016/S1470-2045(15)00302-2DOI Listing
October 2015

The many-faced KSR1: a tumor suppressor in breast cancer.

Oncoscience 2015 25;2(8):669-70. Epub 2015 Aug 25.

Imperial College London, Division of Cancer, Hammersmith Hospital Campus, London, UK.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4580053PMC
http://dx.doi.org/10.18632/oncoscience.219DOI Listing
October 2015

Rare tumors: an eye on the future.

Future Oncol 2015 Oct 8;11(19):2641-2644. Epub 2015 Sep 8.

Department of Oncology, Imperial College, London, UK.

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http://dx.doi.org/10.2217/fon.15.212DOI Listing
October 2015