Publications by authors named "Justin R Cross"

57Publications

Sex Differences in Colon Cancer Metabolism Reveal A Novel Subphenotype.

Sci Rep 2020 03 17;10(1):4905. Epub 2020 Mar 17.

Department of Environmental Health Sciences, Yale School of Public Health, Yale University, New Haven, CT, USA.

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http://dx.doi.org/10.1038/s41598-020-61851-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7078199PMC
March 2020

Proline biosynthesis is a vent for TGFβ-induced mitochondrial redox stress.

EMBO J 2020 Apr 5;39(8):e103334. Epub 2020 Mar 5.

Cancer Biology and Genetics Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

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http://dx.doi.org/10.15252/embj.2019103334DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7156964PMC
April 2020

Comparison of Topical and Intravenous Tranexamic Acid for Total Knee Replacement: A Randomized Double-Blinded Controlled Study of Effects on Tranexamic Acid Levels and Thrombogenic and Inflammatory Marker Levels.

J Bone Joint Surg Am 2019 Dec;101(23):2120-2128

Department of Anesthesiology, Critical Care & Pain Management (K.M.J.-E., A.T., and L.R.B.), Department of Orthopedic Surgery (T.P.S., A.S.M., E.P.S., and D.J.M.), and Biostatistics Core (K.G.F.), Hospital for Special Surgery, New York, NY.

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http://dx.doi.org/10.2106/JBJS.19.00258DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7406146PMC
December 2019

Transsulfuration Activity Can Support Cell Growth upon Extracellular Cysteine Limitation.

Cell Metab 2019 11 10;30(5):865-876.e5. Epub 2019 Oct 10.

Department of Cancer Biology and Genetics, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cmet.2019.09.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6961654PMC
November 2019

Mapping Interactions of Microbial Metabolites with Human G-Protein-Coupled Receptors.

Cell Host Microbe 2019 08 1;26(2):273-282.e7. Epub 2019 Aug 1.

Laboratory of Genetically Encoded Small Molecules, the Rockefeller University, 1230 York Avenue, New York City, NY 10065, USA. Electronic address:

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http://dx.doi.org/10.1016/j.chom.2019.07.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6706627PMC
August 2019

Stable Isotope Tracers for Metabolic Pathway Analysis.

Methods Mol Biol 2019 ;1978:269-283

Donald B. and Catherine C. Cancer Metabolism Center, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

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http://link.springer.com/10.1007/978-1-4939-9236-2_17
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http://dx.doi.org/10.1007/978-1-4939-9236-2_17DOI Listing
November 2019

Nutritional Support from the Intestinal Microbiota Improves Hematopoietic Reconstitution after Bone Marrow Transplantation in Mice.

Cell Host Microbe 2018 04 22;23(4):447-457.e4. Epub 2018 Mar 22.

Department of Immunology, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA; Weill Cornell Medical College, New York, NY 10065, USA; Adult Bone Marrow Transplantation Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA. Electronic address:

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http://dx.doi.org/10.1016/j.chom.2018.03.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5897172PMC
April 2018

In Vivo Imaging of Glutamine Metabolism to the Oncometabolite 2-Hydroxyglutarate in IDH1/2 Mutant Tumors.

Cell Metab 2017 Dec 19;26(6):830-841.e3. Epub 2017 Oct 19.

Department of Radiology, Memorial Sloan Kettering Cancer Center (MSKCC), New York, NY 10065, USA; Molecular Pharmacology Program, Memorial Sloan Kettering Cancer Center (MSKCC), New York, NY 10065, USA; Weill Cornell Medical College, New York, NY 10065, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cmet.2017.10.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5718944PMC
December 2017

MYC-dependent oxidative metabolism regulates osteoclastogenesis via nuclear receptor ERRα.

J Clin Invest 2017 Jun 22;127(7):2555-2568. Epub 2017 May 22.

Arthritis and Tissue Degeneration Program, David Z. Rosensweig Genomics Research Center, Hospital for Special Surgery, New York, New York, USA.

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http://dx.doi.org/10.1172/JCI89935DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5490751PMC
June 2017

L-2-Hydroxyglutarate production arises from noncanonical enzyme function at acidic pH.

Nat Chem Biol 2017 05 6;13(5):494-500. Epub 2017 Mar 6.

Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, New York, USA.

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http://dx.doi.org/10.1038/nchembio.2307DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5516644PMC
May 2017

Carcinoma-astrocyte gap junctions promote brain metastasis by cGAMP transfer.

Nature 2016 05 18;533(7604):493-498. Epub 2016 May 18.

Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.

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http://dx.doi.org/10.1038/nature18268DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5021195PMC
May 2016

Arginase 1 is an innate lymphoid-cell-intrinsic metabolic checkpoint controlling type 2 inflammation.

Nat Immunol 2016 06 4;17(6):656-65. Epub 2016 Apr 4.

Jill Roberts Institute for Research in Inflammatory Bowel Disease, Joan and Sanford I. Weill Department of Medicine, Department of Microbiology and Immunology, Weill Cornell Medicine, Cornell University, New York, New York, USA.

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http://dx.doi.org/10.1038/ni.3421DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4873382PMC
June 2016

Integration of 2-hydroxyglutarate-proton magnetic resonance spectroscopy into clinical practice for disease monitoring in isocitrate dehydrogenase-mutant glioma.

Neuro Oncol 2016 Feb 20;18(2):283-90. Epub 2015 Dec 20.

Department of Neurology, Memorial Sloan Kettering Cancer Center, New York, New York (M.I.d., S.B., A.T., A.A.O., C.P.N., E.P., T.J.K., L.M.D., I.K.M.); Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York (R.J.Y., J.R., J.T., J.A.-P., A.I.H., S.B.T.); Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York (M.R.); Donald B. and Catherine C. Marron Cancer Metabolism Center, Memorial Sloan Kettering Cancer Center, New York, New York (J.R.C.); Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York (C.C., I.K.M.); Department of Neurosurgery, Memorial Sloan Kettering Cancer Center, New York, New York (P.H.G.); Department of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, New York (J.H.O., S.B.T.); Agios Pharmaceuticals, Cambridge, Massachusetts (K.S., D.Z., K.Y.); Department of Neurology, Evelyn F. McKnight Brain Institute, University of Miami, Miami, Florida (C.D.); Advanced Imaging Research Center, University Of Texas Southwestern Medical Center, Dallas, Texas (E.M., C.C.); GE Healthcare, Berlin, Germany (R.N.); Department of Pharmacology, Weill-Cornell Graduate School of Biomedical Sciences, New York, New York (I.K.M.).

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http://dx.doi.org/10.1093/neuonc/nov307DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4724186PMC
February 2016

Hypoxia Induces Production of L-2-Hydroxyglutarate.

Cell Metab 2015 Aug 23;22(2):304-11. Epub 2015 Jul 23.

Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cmet.2015.06.023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4527873PMC
August 2015

Interferon-γ regulates cellular metabolism and mRNA translation to potentiate macrophage activation.

Nat Immunol 2015 Aug 29;16(8):838-849. Epub 2015 Jun 29.

Graduate Program in Immunology and Microbial Pathogenesis, Weill Cornell Graduate School of Medical Sciences, New York, NY 10021.

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http://dx.doi.org/10.1038/ni.3205DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4509841PMC
August 2015

Intracellular crotonyl-CoA stimulates transcription through p300-catalyzed histone crotonylation.

Mol Cell 2015 04 26;58(2):203-15. Epub 2015 Mar 26.

Laboratory of Chromatin Biology and Epigenetics, The Rockefeller University, New York, NY 10065, USA. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2015.02.029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4501262PMC
April 2015

Friends not foes: CTLA-4 blockade and mTOR inhibition cooperate during CD8+ T cell priming to promote memory formation and metabolic readiness.

J Immunol 2015 Mar 26;194(5):2089-98. Epub 2015 Jan 26.

Department of Immunology, Howard Hughes Medical Institute, Memorial Sloan Kettering Cancer Center, New York, NY 10065;

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http://dx.doi.org/10.4049/jimmunol.1402390DOI Listing
March 2015

Intracellular α-ketoglutarate maintains the pluripotency of embryonic stem cells.

Nature 2015 Feb 10;518(7539):413-6. Epub 2014 Dec 10.

Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA.

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http://dx.doi.org/10.1038/nature13981DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4336218PMC
February 2015

Precision microbiome reconstitution restores bile acid mediated resistance to Clostridium difficile.

Nature 2015 Jan 22;517(7533):205-8. Epub 2014 Oct 22.

1] Infectious Diseases Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA [2] Lucille Castori Center for Microbes, Inflammation and Cancer, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA [3] Immunology Program, Sloan-Kettering Institute, New York, New York 10065, USA.

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http://dx.doi.org/10.1038/nature13828DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4354891PMC
January 2015

Serine catabolism regulates mitochondrial redox control during hypoxia.

Cancer Discov 2014 Dec 3;4(12):1406-17. Epub 2014 Sep 3.

Cancer Biology and Genetics Program and Immunology Program, Memorial Sloan Kettering Cancer Center, New York, New York.

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http://dx.doi.org/10.1158/2159-8290.CD-14-0250DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4258153PMC
December 2014

Metabolites produced by commensal bacteria promote peripheral regulatory T-cell generation.

Nature 2013 Dec 13;504(7480):451-5. Epub 2013 Nov 13.

1] Howard Hughes Medical Institute and Ludwig Center at Memorial Sloan-Kettering Cancer Center, New York, New York 10065, USA [2] Immunology Program, Memorial Sloan-Kettering Cancer Center, New York, New York 10065, USA.

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http://www.nature.com/articles/nature12726
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http://dx.doi.org/10.1038/nature12726DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3869884PMC
December 2013

Cancer-associated IDH2 mutants drive an acute myeloid leukemia that is susceptible to Brd4 inhibition.

Genes Dev 2013 Sep;27(18):1974-85

Cancer Biology and Genetics Program, Memorial Sloan-Kettering Cancer Center, New York, New York 10065, USA;

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http://dx.doi.org/10.1101/gad.226613.113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3792474PMC
September 2013

Hypoxic and Ras-transformed cells support growth by scavenging unsaturated fatty acids from lysophospholipids.

Proc Natl Acad Sci U S A 2013 May 13;110(22):8882-7. Epub 2013 May 13.

Lewis-Sigler Institute for Integrative Genomics and Department of Chemistry, Princeton University, Princeton, NJ 08544, USA.

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http://dx.doi.org/10.1073/pnas.1307237110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3670379PMC
May 2013

The potential for isocitrate dehydrogenase mutations to produce 2-hydroxyglutarate depends on allele specificity and subcellular compartmentalization.

J Biol Chem 2013 Feb 21;288(6):3804-15. Epub 2012 Dec 21.

Cancer Biology and Genetics Program, Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, New York 10065, USA.

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http://dx.doi.org/10.1074/jbc.M112.435495DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3567635PMC
February 2013

ATP-citrate lyase links cellular metabolism to histone acetylation.

Science 2009 May;324(5930):1076-80

Department of Cancer Biology, Abramson Family Cancer Research Institute, University of Pennsylvania, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1126/science.1164097DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2746744PMC
May 2009

The X-linked mental retardation protein oligophrenin-1 is required for dendritic spine morphogenesis.

Nat Neurosci 2004 Apr 14;7(4):364-72. Epub 2004 Mar 14.

Cold Spring Harbor Laboratory, 1 Bungtown Road, Cold Spring Harbor, New York 11724, USA.

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http://dx.doi.org/10.1038/nn1210DOI Listing
April 2004