Justin J Greenlee

Justin J Greenlee

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Justin J Greenlee

Justin J Greenlee

Publications by authors named "Justin J Greenlee"

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In Situ Temporospatial Characterization of the Glial Response to Prion Infection.

Vet Pathol 2019 Jul 22:300985819861708. Epub 2019 Jul 22.

1 Department of Veterinary Pathology, College of Veterinary Medicine, Iowa State University, Ames, IA, USA.

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http://dx.doi.org/10.1177/0300985819861708DOI Listing
July 2019

Sheep With the Homozygous Lysine-171 Prion Protein Genotype Are Resistant to Classical Scrapie After Experimental Oronasal Inoculation.

Vet Pathol 2019 05 17;56(3):409-417. Epub 2018 Dec 17.

2 United States Department of Agriculture, Virus and Prion Research Unit, National Animal Disease Center, Agricultural Research Service, Ames, IA, USA.

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http://dx.doi.org/10.1177/0300985818817066DOI Listing
May 2019

Source genotype influence on cross species transmission of transmissible spongiform encephalopathies evaluated by RT-QuIC.

PLoS One 2018 20;13(12):e0209106. Epub 2018 Dec 20.

United States Department of Agriculture, Agricultural Research Service, National Animal Disease Center, Virus and Prion Research Unit, Ames, Iowa, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0209106PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6301698PMC
May 2019

Pathology in Practice.

J Am Vet Med Assoc 2019 Apr;254(7):819-821

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http://dx.doi.org/10.2460/javma.254.7.819DOI Listing
April 2019

Raccoons accumulate PrP after intracranial inoculation of the agents of chronic wasting disease or transmissible mink encephalopathy but not atypical scrapie.

J Vet Diagn Invest 2019 Mar 29;31(2):200-209. Epub 2019 Jan 29.

National Animal Disease Center, Ames, IA (Moore, Greenlee).

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http://dx.doi.org/10.1177/1040638718825290DOI Listing
March 2019

Review: Update on Classical and Atypical Scrapie in Sheep and Goats.

Vet Pathol 2019 Jan 10;56(1):6-16. Epub 2018 Sep 10.

1 Virus and Prion Research Unit, National Animal Disease Center, Agricultural Research Service, United States Department of Agriculture, Ames, IA, USA.

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http://dx.doi.org/10.1177/0300985818794247DOI Listing
January 2019

Accelerated accumulation of retinal α-synuclein (pSer129) and tau, neuroinflammation, and autophagic dysregulation in a seeded mouse model of Parkinson's disease.

Neurobiol Dis 2019 01 12;121:1-16. Epub 2018 Sep 12.

Immunobiology Graduate Program, Iowa State University, United States; Neuroscience Graduate Program, Iowa State University, United States; Department of Biomedical Sciences, Iowa State University College of Veterinary Medicine, Ames, IA, United States. Electronic address:

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http://dx.doi.org/10.1016/j.nbd.2018.09.013DOI Listing
January 2019

Real-Time Quaking-Induced Conversion Detection of Bovine Spongiform Encephalopathy Prions in a Subclinical Steer.

Front Vet Sci 2017 19;4:242. Epub 2018 Jan 19.

United States Department of Agriculture, Agricultural Research Service, National Animal Disease Center, Virus and Prion Research Unit, Ames, IA, United States.

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http://dx.doi.org/10.3389/fvets.2017.00242DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5780402PMC
January 2018

Effects of a naturally occurring amino acid substitution in bovine PrP: a model for inherited prion disease in a natural host species.

BMC Res Notes 2017 Dec 20;10(1):759. Epub 2017 Dec 20.

United States Department of Agriculture, Agricultural Research Service, National Animal Disease Center, Ames, IA, USA.

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http://dx.doi.org/10.1186/s13104-017-3085-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5738711PMC
December 2017

Experimental Transmission of the Chronic Wasting Disease Agent to Swine after Oral or Intracranial Inoculation.

J Virol 2017 10 12;91(19). Epub 2017 Sep 12.

Virus and Prion Research Unit, National Animal Disease Center, USDA, Agricultural Research Service, Ames, Iowa, USA

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http://dx.doi.org/10.1128/JVI.00926-17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5599732PMC
October 2017

Use of bovine recombinant prion protein and real-time quaking-induced conversion to detect cattle transmissible mink encephalopathy prions and discriminate classical and atypical L- and H-Type bovine spongiform encephalopathy.

PLoS One 2017 22;12(2):e0172391. Epub 2017 Feb 22.

Virus and Prion Research Unit, National Animal Disease Center, Agricultural Research Service, United States Department of Agriculture, Ames, IA, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0172391PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5321280PMC
August 2017

Lasting Retinal Injury in a Mouse Model of Blast-Induced Trauma.

Am J Pathol 2017 Jul 9;187(7):1459-1472. Epub 2017 Jun 9.

Immunobiology Graduate Program, Iowa State University, Ames, Iowa; Neuroscience Graduate Program, Iowa State University, Ames, Iowa; Department of Biomedical Sciences, Iowa State University College of Veterinary Medicine, Ames, Iowa. Electronic address:

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http://dx.doi.org/10.1016/j.ajpath.2017.03.005DOI Listing
July 2017

A Comparison of Classical and H-Type Bovine Spongiform Encephalopathy Associated with E211K Prion Protein Polymorphism in Wild-Type and EK211 Cattle Following Intracranial Inoculation.

Front Vet Sci 2016 15;3:78. Epub 2016 Sep 15.

Virus and Prion Research Unit, Agricultural Research Service, National Animal Disease Center, United States Department of Agriculture , Ames, IA , USA.

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http://dx.doi.org/10.3389/fvets.2016.00078DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5023952PMC
September 2016

Limited amplification of chronic wasting disease prions in the peripheral tissues of intracerebrally inoculated cattle.

J Gen Virol 2016 07 31;97(7):1720-4. Epub 2016 Mar 31.

1​ Department of Diagnostic Medicine and Pathobiology, College of Veterinary Medicine, Kansas State University, Manhattan, KS, USA.

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http://dx.doi.org/10.1099/jgv.0.000438DOI Listing
July 2016

Lack of prion accumulation in lymphoid tissues of PRNP ARQ/ARR sheep intracranially inoculated with the agent of scrapie.

PLoS One 2014 18;9(9):e108029. Epub 2014 Sep 18.

Virus and Prion Research Unit, National Animal Disease Center, Agricultural Research Service, United States Department of Agriculture, Ames, Iowa, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0108029PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4169493PMC
April 2016

Oral inoculation of neonatal Suffolk sheep with the agent of classical scrapie results in PrP(Sc) accumulation in sheep with the PRNP ARQ/ARQ but not the ARQ/ARR genotype.

Res Vet Sci 2016 Apr 24;105:188-91. Epub 2016 Feb 24.

Virus and Prion Research Unit, National Animal Disease Center, USDA, Agricultural Research Service, 1920 Dayton Avenue, Ames, IA 50010, USA.

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http://dx.doi.org/10.1016/j.rvsc.2016.02.016DOI Listing
April 2016

The transmissible spongiform encephalopathies of livestock.

ILAR J 2015 ;56(1):7-25

Justin J. Greenlee, DVM, PhD, Diplomate ACVP, is a research veterinary medical officer in the Virus and Prion Research Unit of the National Animal Disease Center, U.S. Department of Agriculture, Agricultural Research Service in Ames, Iowa. M. Heather West Greenlee, PhD, is an associate professor of biomedical sciences at the Iowa State University College of Veterinary Medicine.

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http://dx.doi.org/10.1093/ilar/ilv008DOI Listing
March 2016

Transmission of scrapie prions to primate after an extended silent incubation period.

Sci Rep 2015 Jun 30;5:11573. Epub 2015 Jun 30.

Atomic Energy Commission (CEA), Institute of Emerging Diseases and Innovative therapies (iMETI), Division of Prions and related Diseases (SEPIA), 18 Route du Panorama, BP6, 92265 Fontenay-aux-Roses, France.

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http://dx.doi.org/10.1038/srep11573DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4485159PMC
June 2015

Clinical and pathologic features of H-type bovine spongiform encephalopathy associated with E211K prion protein polymorphism.

PLoS One 2012 8;7(6):e38678. Epub 2012 Jun 8.

National Animal Disease Center, United States Department of Agriculture, Agricultural Research Service, Ames, Iowa, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0038678PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3371052PMC
February 2015

hTERT-immortalized ovine microglia propagate natural scrapie isolates.

Virus Res 2015 Feb 12;198:35-43. Epub 2015 Jan 12.

Department of Microbiology and Pathology, College of Veterinary Medicine, Washington State University, PO Box 64700, Pullman, WA 99164-7010, United States. Electronic address:

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http://dx.doi.org/10.1016/j.virusres.2014.10.028DOI Listing
February 2015

Detection of misfolded prion protein in retina samples of sheep and cattle by use of a commercially available enzyme immunoassay.

Am J Vet Res 2014 Mar;75(3):268-72

Virus and Prion Research Unit, National Animal Disease Center, Agricultural Research Service, USDA, Ames, IA 50010.

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http://dx.doi.org/10.2460/ajvr.75.3.268DOI Listing
March 2014

Stability properties of PrP(Sc) from cattle with experimental transmissible spongiform encephalopathies: use of a rapid whole homogenate, protease-free assay.

BMC Vet Res 2013 Aug 15;9:167. Epub 2013 Aug 15.

Virus and Prion Disease Research Unit, National Animal Disease Center, USDA, Agricultural Research Service, Ames, IA 50010, USA.

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http://dx.doi.org/10.1186/1746-6148-9-167DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3751458PMC
August 2013

Evaluation of the zoonotic potential of transmissible mink encephalopathy.

Pathogens 2013 Jul 30;2(3):520-32. Epub 2013 Jul 30.

CEA, Institute of Emerging Diseases and Innovative Therapies (iMETI), Division of Prions and Related Diseases (SEPIA), Route du Panorama, BP6, 92265 Fontenay-aux-Roses, France.

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http://dx.doi.org/10.3390/pathogens2030520DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4235697PMC
July 2013

Evaluation of a combinatorial approach to prion inactivation using an oxidizing agent, SDS, and proteinase K.

BMC Vet Res 2013 Jul 25;9:151. Epub 2013 Jul 25.

Virus and Prion Research Unit, National Animal Disease Center, Agricultural Research Service, USDA, 1920 Dayton Ave, Ames, IA 50010, USA.

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http://dx.doi.org/10.1186/1746-6148-9-151DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3728008PMC
July 2013

Relationships between PrPSc stability and incubation time for United States scrapie isolates in a natural host system.

PLoS One 2012 14;7(8):e43060. Epub 2012 Aug 14.

National Animal Disease Center, Agricultural Research Service, United States Department of Agriculture, Ames, Iowa, USA.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0043060PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3419241PMC
January 2013

Exposure of RML scrapie agent to a sodium percarbonate-based product and sodium dodecyl sulfate renders PrPSc protease sensitive but does not eliminate infectivity.

BMC Vet Res 2013 Jan 11;9. Epub 2013 Jan 11.

Virus and Prion Research Unit, National Animal Disease Center, USDA, Agricultural Research Service, 1920 Dayton Ave, Ames, IA 50010, USA.

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http://dx.doi.org/10.1186/1746-6148-9-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3599183PMC
January 2013

Susceptibility of cattle to the agent of chronic wasting disease from elk after intracranial inoculation.

J Vet Diagn Invest 2012 Nov 18;24(6):1087-93. Epub 2012 Sep 18.

Virus and Prion Research Unit, National Animal Disease Center, U.S. Department of Agriculture, Agricultural Research Service, Ames, IA, USA.

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http://dx.doi.org/10.1177/1040638712461249DOI Listing
November 2012

Salivary prions in sheep and deer.

Prion 2012 Jan-Mar;6(1):52-61

Institute for Neurodegenerative Diseases, Department of Neurology, University of California, San Francisco, CA, USA.

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http://dx.doi.org/10.4161/pri.6.1.16984DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3338966PMC
August 2012

Prolonged incubation time in sheep with prion protein containing lysine at position 171.

J Vet Diagn Invest 2012 May;24(3):554-8

Virus and Prion Diseases of Livestock Research Unit, National Animal Disease Center, Agricultural Research Service, USDA, 1920 Dayton Avenue, PO Box 70, Ames, IA 50010, USA.

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http://dx.doi.org/10.1177/1040638712440993DOI Listing
May 2012

White-tailed deer are susceptible to the agent of sheep scrapie by intracerebral inoculation.

Vet Res 2011 Oct 11;42:107. Epub 2011 Oct 11.

Virus and Prion Research Unit, National Animal Disease Center, ARS, USDA, Ames, IA 50010, USA.

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http://dx.doi.org/10.1186/1297-9716-42-107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3199251PMC
October 2011

PrPSc detection in formalin-fixed paraffin-embedded tissue by ELISA.

BMC Res Notes 2011 Oct 21;4:432. Epub 2011 Oct 21.

Virus and Prion Research Unit, 1920 Dayton Ave,, National Animal Disease Center, USDA, Agricultural Research Service, Ames, Iowa 50010, USA.

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http://dx.doi.org/10.1186/1756-0500-4-432DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3225400PMC
October 2011

Experimental interspecies transmission studies of the transmissible spongiform encephalopathies to cattle: comparison to bovine spongiform encephalopathy in cattle.

J Vet Diagn Invest 2011 May;23(3):407-20

Virus and Prion Research Unit, National Animal Disease Center-USDA-Agricultural Research Service, 1920 Dayton Avenue, PO Box 70, Ames, IA 50010, USA.

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http://journals.sagepub.com/doi/10.1177/1040638711403404
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http://dx.doi.org/10.1177/1040638711403404DOI Listing
May 2011

Experimental transmission of chronic wasting disease (CWD) from elk and white-tailed deer to fallow deer by intracerebral route: final report.

Can J Vet Res 2011 Apr;75(2):152-6

National Animal Disease Center, Agricultural Research Service, United States Department of Agriculture, 1920 Dayton Avenue, PO Box 70, Ames, Iowa, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3062927PMC
April 2011

Bronchial carcinoma in a red-shouldered hawk (Buteo lineatus).

J Zoo Wildl Med 2011 Mar;42(1):153-5

Department of Veterinary Pathology, 2764 Veterinary Medicine, Iowa State University, Ames, Iowa 50011, USA.

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http://www.bioone.org/doi/abs/10.1638/2010-0112.1
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http://dx.doi.org/10.1638/2010-0112.1DOI Listing
March 2011

Identification of an amino acid domain encoded by the capsid gene of porcine circovirus type 2 that modulates intracellular viral protein distribution during replication.

Virus Res 2011 Jan 8;155(1):358-62. Epub 2010 Oct 8.

Virus and Prion Research Unit, National Animal Disease Center, USDA, Agricultural Research Service, PO Box 70, Ames, IA 50010, USA.

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http://dx.doi.org/10.1016/j.virusres.2010.09.021DOI Listing
January 2011

Experimental inoculation of raccoons (Procyon lotor) with Spiroplasma mirum and transmissible mink encephalopathy (TME).

Can J Vet Res 2011 Jan;75(1):18-24

National Animal Disease Center, Agricultural Research Service, U.S. Department of Agriculture, Ames, Iowa 50010, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3003558PMC
January 2011

Experimental oral transmission of United States origin scrapie to neonatal sheep.

J Vet Diagn Invest 2009 Jan;21(1):64-8

US Department of Agriculture, National Animal Disease Center, Agricultural Research Service, USDA, Ames, IA 50010, USA.

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http://dx.doi.org/10.1177/104063870902100110DOI Listing
January 2009

Ablation of prion protein immunoreactivity by heating in saturated calcium hydroxide.

BMC Res Notes 2008 Oct 28;1:99. Epub 2008 Oct 28.

Virus and Prion Diseases of Livestock Research Unit, National Animal Disease Center, USDA, Agricultural Research Service, 2300 Dayton Avenue, Ames, IA, USA, 50010.

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http://dx.doi.org/10.1186/1756-0500-1-99DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2588617PMC
October 2008

Frequencies of polymorphisms associated with BSE resistance differ significantly between Bos taurus, Bos indicus, and composite cattle.

BMC Vet Res 2008 Sep 22;4:36. Epub 2008 Sep 22.

Virus and Prion Diseases of Livestock Research Unit, National Animal Disease Center, USDA, Agricultural Research Service, Ames, IA 50010 USA.

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http://dx.doi.org/10.1186/1746-6148-4-36DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2569919PMC
September 2008

Identification of a heritable polymorphism in bovine PRNP associated with genetic transmissible spongiform encephalopathy: evidence of heritable BSE.

PLoS One 2008 Aug 13;3(8):e2912. Epub 2008 Aug 13.

Virus and Prion Diseases of Livestock Research Unit, National Animal Disease Center, USDA, Agricultural Research Service, Ames, Iowa, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0002912PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2488391PMC
August 2008

Western blot detection of PrP Sc in archived paraffin-embedded brainstem from scrapie-affected sheep.

J Vet Diagn Invest 2008 Jul;20(4):522-6

National Animal Disease Center, US Department of Agriculture, Animal Research Service, Ames, IA 50010, USA.

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http://dx.doi.org/10.1177/104063870802000421DOI Listing
July 2008

Elk with a long incubation prion disease phenotype have a unique PrPd profile.

Neuroreport 2007 Dec;18(18):1935-8

United States Department of Agriculture, Agricultural Research Service, Animal Disease Research Unit, Pullman, Washington 99164, USA.

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http://dx.doi.org/10.1097/WNR.0b013e3282f1ca2fDOI Listing
December 2007

Experimental canine leptospirosis caused by Leptospira interrogans serovars pomona and bratislava.

Am J Vet Res 2005 Oct;66(10):1816-22

Department of Veterinary Pathology, College of Veterinary Medicine, Iowa State University, Ames, IA 50011, USA.

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October 2005

Clinical and pathologic comparison of acute leptospirosis in dogs caused by two strains of Leptospira kirschneri serovar grippotyphosa.

Am J Vet Res 2004 Aug;65(8):1100-7

Diagnostic Center for Population and Animal Health, College of Veterinary Medicine, Michigan State University, East Lansing, MI 48824, USA.

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August 2004

An improved immunohistochemical diagnostic technique for canine leptospirosis using antileptospiral antibodies on renal tissue.

J Vet Diagn Invest 2002 Jan;14(1):20-4

Department of Veterinary Pathology, College of Veterinary Medicine, Iowa State University, Ames, IA 50011, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2666280PMC
http://dx.doi.org/10.1177/104063870201400105DOI Listing
January 2002