Publications by authors named "Jurgen Hescheler"

100Publications

Non-Mendelian inheritance during inbreeding of Ca3.2 and Ca2.3 deficient mice.

Sci Rep 2020 10 2;10(1):15993. Epub 2020 Oct 2.

Institute for Neurophysiology, University of Cologne, Robert-Koch-Str. 39, 50931, Cologne, Germany.

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http://dx.doi.org/10.1038/s41598-020-72912-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7532468PMC
October 2020

Stem cells in natural product and medicinal plant drug discovery-An overview of new screening approaches.

Biomed Pharmacother 2020 Nov 10;131:110730. Epub 2020 Sep 10.

Institute of Neurophysiology, University of Cologne, 50931, Cologne, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.biopha.2020.110730DOI Listing
November 2020

Radiation Response of Murine Embryonic Stem Cells.

Cells 2020 07 9;9(7). Epub 2020 Jul 9.

Institute of Neurophysiology and Center for Molecular Medicine Cologne (CMMC), University of Cologne, Robert-Koch-Str. 39, 50931 Cologne, Germany.

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http://dx.doi.org/10.3390/cells9071650DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7408589PMC
July 2020

Zn2+-induced changes in Cav2.3 channel function: An electrophysiological and modeling study.

J Gen Physiol 2020 09;152(9)

University of Cologne, Faculty of Medicine and University Hospital Cologne, Institute for Neurophysiology, Cologne, Germany.

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http://dx.doi.org/10.1085/jgp.202012585DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7478874PMC
September 2020

Epac-mediated relaxation in murine basilar arteries depends on membrane permeability of cyclic nucleotide analogues and endothelial aging.

Gen Physiol Biophys 2020 Mar;39(2):157-168

Institute of Vegetative Physiology, Center of Physiology, University of Cologne, Cologne, Germany.

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http://dx.doi.org/10.4149/gpb_2019055DOI Listing
March 2020

Mechano-Pharmacological Testing of L-Type Ca Channel Modulators via Human Vascular Celldrum Model.

Cell Physiol Biochem 2020 Apr;54(3):371-383

Institute for Neurophysiology, University Cologne, Cologne, Germany.

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http://dx.doi.org/10.33594/000000225DOI Listing
April 2020

Cyclooxygenases Inhibitors Efficiently Induce Cardiomyogenesis in Human Pluripotent Stem Cells.

Cells 2020 02 27;9(3). Epub 2020 Feb 27.

Institute of Neurophysiology, Faculty of Medicine, University of Cologne, Robert-Koch-Str. 39, 50931 Cologne, Germany.

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http://dx.doi.org/10.3390/cells9030554DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7140528PMC
February 2020

Experimentally Induced Convulsive Seizures Are Modulated in Part by Zinc Ions through the Pharmacoresistant Ca2.3 Calcium Channel.

Cell Physiol Biochem 2020 Feb;54(2):180-194

Institute for Neurophysiology, University of Cologne, Köln, Germany,

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http://dx.doi.org/10.33594/000000213DOI Listing
February 2020

Stem cells for regenerative medicine and anti-aging.

Authors:
Jurgen Hescheler

J Stem Cells Regen Med 2019 24;15(2):53. Epub 2019 Dec 24.

Dept. of Neurophysiology, University of Cologne, Germany.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6971379PMC
December 2019

Evaluation of chemotherapy with nanosomal paclitaxel and gene therapy expressing apoptosis-inducing proteins in the management of spontaneous canine mammary neoplasm.

J Stem Cells Regen Med 2019 24;15(2):24-34. Epub 2019 Dec 24.

Director, Institute of Neurophysiology, Universität zu Köln, Robert-Koch-Strasse 39, D-50931, Köln, Germany.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6971383PMC
December 2019

Functional implications of Ca 2.3 R-type voltage-gated calcium channels in the murine auditory system - novel vistas from brainstem-evoked response audiometry.

Eur J Neurosci 2020 Apr 3;51(7):1583-1604. Epub 2019 Nov 3.

Experimental Neuropsychopharmacology, Federal Institute for Drugs and Medical Devices (Bundesinstitut für Arzneimittel und Medizinprodukte, BfArM), Bonn, Germany.

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http://dx.doi.org/10.1111/ejn.14591DOI Listing
April 2020

Ketamine Increases Proliferation of Human iPSC-Derived Neuronal Progenitor Cells via Insulin-Like Growth Factor 2 and Independent of the NMDA Receptor.

Cells 2019 09 24;8(10). Epub 2019 Sep 24.

Bio-Pharmaceutical Chemistry and Molecular Pharmacology, Faculty of Applied Natural Sciences, Technische Hochschule Köln, 51373 Leverkusen, Germany.

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http://dx.doi.org/10.3390/cells8101139DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6830315PMC
September 2019

Complex Clearance Mechanisms After Intraventricular Hemorrhage and rt-PA Treatment-a Review on Clinical Trials.

Transl Stroke Res 2020 06 14;11(3):337-344. Epub 2019 Sep 14.

Institute of Neurophysiology, Medical Faculty, University of Cologne, Cologne, Germany.

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http://dx.doi.org/10.1007/s12975-019-00735-6DOI Listing
June 2020

Intracerebroventricular administration of histidine reduces kainic acid-induced convulsive seizures in mice.

Exp Brain Res 2019 Oct 18;237(10):2481-2493. Epub 2019 Jul 18.

Institute for Neurophysiology, University of Cologne, Robert-Koch-Str. 39, 50931, Koeln, Germany.

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http://dx.doi.org/10.1007/s00221-019-05605-zDOI Listing
October 2019

Application of Stem Cell Technologies to Regenerate Injured Myocardium and Improve Cardiac Function.

Cell Physiol Biochem 2019 ;53(1):101-120

Institute of Neurophysiology, University of Cologne, Cologne, Germany.

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http://dx.doi.org/10.33594/000000124DOI Listing
July 2019

Data Acquisition and Analysis In Brainstem Evoked Response Audiometry In Mice.

J Vis Exp 2019 05 10(147). Epub 2019 May 10.

Experimental Neuropsychopharmacology, Federal Institute for Drugs and Medical Devices;

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http://dx.doi.org/10.3791/59200DOI Listing
May 2019

In Vitro Grown Micro-Tissues for Cardiac Cell Replacement Therapy in Vivo.

Cell Physiol Biochem 2019 ;52(6):1309-1324

Center for Physiology and Pathophysiology, Institute of Neurophysiology, Medical Faculty, University of Cologne, Cologne, Germany.

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http://dx.doi.org/10.33594/000000092DOI Listing
May 2019

Ca3.2 T-Type Calcium Channels Are Physiologically Mandatory for the Auditory System.

Neuroscience 2019 06 25;409:81-100. Epub 2019 Apr 25.

Experimental Neuropsychopharmacology, Federal Institute for Drugs and Medical Devices (Bundesinstitut für Arzneimittel und Medizinprodukte, BfArM), Kurt-Georg-Kiesinger-Allee 3, 53175 Bonn, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.neuroscience.2019.04.024DOI Listing
June 2019

Parabolic, Flight-Induced, Acute Hypergravity and Microgravity Effects on the Beating Rate of Human Cardiomyocytes.

Cells 2019 04 14;8(4). Epub 2019 Apr 14.

Institute of Neurophysiology, Center for Molecular Medicine Cologne (CMMC), University of Cologne, 50931 Cologne, Germany.

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http://dx.doi.org/10.3390/cells8040352DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6523861PMC
April 2019

Different Responses to Drug Safety Screening Targets between Human Neonatal and Infantile Heart Tissue and Cardiac Bodies Derived from Human-Induced Pluripotent Stem Cells.

Stem Cells Int 2019 6;2019:6096294. Epub 2019 Mar 6.

Department of Paediatric Cardiology, Heart Centre Cologne, University Hospital of Cologne, Kerpener Str. 52, 50924 Cologne, Germany.

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http://dx.doi.org/10.1155/2019/6096294DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6431377PMC
March 2019

Gender specific click and tone burst evoked ABR datasets from mice lacking the Ca3.2 T-type voltage-gated calcium channel.

BMC Res Notes 2019 Mar 20;12(1):157. Epub 2019 Mar 20.

Experimental Neuropsychopharmacology, Federal Institute for Drugs and Medical Devices (Bundesinstitut für Arzneimittel und Medizinprodukte, BfArM), Kurt-Georg-Kiesinger-Allee 3, 53175, Bonn, Germany.

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https://bmcresnotes.biomedcentral.com/articles/10.1186/s1310
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http://dx.doi.org/10.1186/s13104-019-4169-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425560PMC
March 2019

Long Term Perinatal Deltamethrin Exposure Alters Electrophysiological Properties of Embryonic Ventricular Cardiomyocyte.

Curr Med Sci 2019 Feb 13;39(1):21-27. Epub 2019 Mar 13.

Department of Pharmaceutics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.

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http://dx.doi.org/10.1007/s11596-019-1995-5DOI Listing
February 2019

Cardiomyocytes facing fibrotic conditions re-express extracellular matrix transcripts.

Acta Biomater 2019 04 9;89:180-192. Epub 2019 Mar 9.

Institute of Neurophysiology, University of Cologne, Cologne, Germany; Department of Pediatric Cardiology, University Hospital Cologne, Cologne, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.actbio.2019.03.017DOI Listing
April 2019

STAT3 Phosphorylation Mediating DMSO's Function on Fetal Cardiomyocyte Proliferation with Developmental Changes.

Int Heart J 2019 Mar 8;60(2):392-399. Epub 2019 Feb 8.

Department of Physiology, Hubei Key Laboratory of Drug Target Research and Pharmacodynamic Evaluation, School of Basic Medicine, Huazhong University of Science and Technology.

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http://dx.doi.org/10.1536/ihj.18-206DOI Listing
March 2019

Gender specific click and tone burst evoked ABR datasets from mice lacking the Ca2.3 R-type voltage-gated calcium channel.

Data Brief 2018 Dec 24;21:1263-1266. Epub 2018 Oct 24.

Experimental Neuropsychopharmacology, Federal Institute for Drugs and Medical Devices (Bundesinstitut für Arzneimittel und Medizinprodukte, BfArM), Kurt-Georg-Kiesinger-Allee 3, 53175 Bonn, Germany.

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http://dx.doi.org/10.1016/j.dib.2018.10.056DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6231286PMC
December 2018

Parallel Genome-wide Profiling of Coding and Non-coding RNAs to Identify Novel Regulatory Elements in Embryonic and Maturated Heart.

Mol Ther Nucleic Acids 2018 Sep 4;12:158-173. Epub 2018 May 4.

University of Cologne (UKK), Institute of Neurophysiology and Center for Molecular Medicine Cologne (CMMC), Robert-Koch-Str. 39, 50931 Cologne, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.omtn.2018.04.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6023836PMC
September 2018

Reciprocal modulation of Ca 2.3 voltage-gated calcium channels by copper(II) ions and kainic acid.

J Neurochem 2018 11 30;147(3):310-322. Epub 2018 Aug 30.

Institute for Neurophysiology, University of Cologne, Cologne, Germany.

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http://dx.doi.org/10.1111/jnc.14546DOI Listing
November 2018

Protein phosphorylation maintains the normal function of cloned human Ca2.3 channels.

J Gen Physiol 2018 03 16;150(3):491-510. Epub 2018 Feb 16.

Institute for Neurophysiology, University of Cologne, Cologne, Germany.

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http://www.jgp.org/lookup/doi/10.1085/jgp.201711880
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http://dx.doi.org/10.1085/jgp.201711880DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5839719PMC
March 2018

Skeletal Extracellular Matrix Supports Cardiac Differentiation of Embryonic Stem Cells: a Potential Scaffold for Engineered Cardiac Tissue.

Cell Physiol Biochem 2018 19;45(1):319-331. Epub 2018 Jan 19.

Department of Physiology and Chinese-German Stem Cell Center, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

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http://dx.doi.org/10.1159/000486813DOI Listing
March 2018

Cell death mechanisms of the anti-cancer drug etoposide on human cardiomyocytes isolated from pluripotent stem cells.

Arch Toxicol 2018 Apr 3;92(4):1507-1524. Epub 2018 Feb 3.

Institute of Neurophysiology and Center for Molecular Medicine Cologne (CMMC), University of Cologne (UKK), Robert-Koch-Str. 39, 50931, Cologne, Germany.

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http://dx.doi.org/10.1007/s00204-018-2170-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5882643PMC
April 2018

Altered Functional Expression of β-Adrenergic Receptors in Rhesus Monkey Embryonic Stem Cell-Derived Cardiomyocytes.

Stem Cells Dev 2018 03 12;27(5):336-346. Epub 2018 Feb 12.

1 Institute of Neurophysiology, University of Cologne , Cologne, Germany .

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http://dx.doi.org/10.1089/scd.2017.0053DOI Listing
March 2018

Puerarin Enhances Ca2+ Reuptake and Ca2+ Content of Sarcoplasmic Reticulum in Murine Embryonic Stem Cell-Derived Cardiomyocytes via Upregulation of SERCA2a.

Cell Physiol Biochem 2017 28;44(3):1199-1212. Epub 2017 Nov 28.

Department of Physiology and Chinese-German Stem Cell Center, School of Basic Medicine, Huazhong University of Science and Technology, The Key Laboratory for Drug Target Researches and Pharmacodynamic Evaluation of Hubei Province, Wuhan, China.

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http://dx.doi.org/10.1159/000485450DOI Listing
January 2018

Pacsin 2 is required for the maintenance of a normal cardiac function in the developing mouse heart.

Pharmacol Res 2018 02 28;128:200-210. Epub 2017 Oct 28.

Institute of Neurophysiology, University of Cologne, 50931 Cologne, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.phrs.2017.10.004DOI Listing
February 2018

Depletion of Mageb16 induces differentiation of pluripotent stem cells predominantly into mesodermal derivatives.

Sci Rep 2017 10 27;7(1):14285. Epub 2017 Oct 27.

University of Cologne (UKK), Institute of Neurophysiology and Center for Molecular Medicine Cologne (CMMC), Robert-Koch-Str. 39, 50931, Cologne, Germany.

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http://dx.doi.org/10.1038/s41598-017-14561-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5660239PMC
October 2017

Functional cardiotoxicity assessment of cosmetic compounds using human-induced pluripotent stem cell-derived cardiomyocytes.

Arch Toxicol 2018 Jan 22;92(1):371-381. Epub 2017 Sep 22.

Institute of Neurophysiology and Center for Molecular Medicine Cologne (CMMC), University of Cologne (UKK), Robert-Koch-Str. 39, 50931, Cologne, Germany.

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http://dx.doi.org/10.1007/s00204-017-2065-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5773645PMC
January 2018

STRIP2 Is Indispensable for the Onset of Embryonic Stem Cell Differentiation.

Mol Ther Methods Clin Dev 2017 Jun 14;5:116-129. Epub 2017 Apr 14.

Institute of Neurophysiology and Center for Molecular Medicine Cologne (CMMC), University of Cologne (UKK), Robert-Koch-Strasse 39, 50931 Cologne, Germany.

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http://dx.doi.org/10.1016/j.omtm.2017.04.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5415327PMC
June 2017

Metabolite signatures of doxorubicin induced toxicity in human induced pluripotent stem cell-derived cardiomyocytes.

Amino Acids 2017 Dec 18;49(12):1955-1963. Epub 2017 Apr 18.

Institute of Neurophysiology and Center for Molecular Medicine Cologne (CMMC), University of Cologne (UKK), Robert-Koch-Str. 39, 50931, Cologne, Germany.

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http://dx.doi.org/10.1007/s00726-017-2419-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5696498PMC
December 2017

Mesenchymal stem cells-seeded bio-ceramic construct for bone regeneration in large critical-size bone defect in rabbit.

J Stem Cells Regen Med 2016 29;12(2):87-99. Epub 2016 Nov 29.

Director, Institute of Neurophysiology, Universität zu Köln, Robert-Koch-Strasse 39, D-50931, Köln, Germany.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5227108PMC
November 2016

Multiple nickel-sensitive targets elicit cardiac arrhythmia in isolated mouse hearts after pituitary adenylate cyclase-activating polypeptide-mediated chronotropy.

Pharmacol Res 2017 03 19;117:140-147. Epub 2016 Dec 19.

Institute of Neurophysiology, University of Köln, Robert-Koch-Str. 39, D-50931 Köln, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.phrs.2016.12.025DOI Listing
March 2017

Murine transgenic iPS cell line for monitoring and selection of cardiomyocytes.

Stem Cell Res 2016 09 21;17(2):266-272. Epub 2016 Jul 21.

Center for Physiology and Pathophysiology, Institute for Neurophysiology, Medical Faculty, University of Cologne, Cologne, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.scr.2016.07.007DOI Listing
September 2016

Surgical Approaches in Psychiatry: A Survey of the World Literature on Psychosurgery.

World Neurosurg 2017 Jan 13;97:603-634.e8. Epub 2016 Oct 13.

Department of Neurosurgery, RWTH Aachen University, Aachen, Germany.

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http://dx.doi.org/10.1016/j.wneu.2016.10.008DOI Listing
January 2017

From Early Embryonic to Adult Stage: Comparative Study of Action Potentials of Native and Pluripotent Stem Cell-Derived Cardiomyocytes.

Stem Cells Dev 2016 10 30;25(19):1397-406. Epub 2016 Aug 30.

1 Department of Internal Medicine III, University of Cologne , Cologne, Germany .

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http://dx.doi.org/10.1089/scd.2016.0073DOI Listing
October 2016

Thymosin β4 impeded murine stem cell proliferation with an intact cardiovascular differentiation.

J Huazhong Univ Sci Technolog Med Sci 2016 Jun 5;36(3):328-334. Epub 2016 Jul 5.

Department of Physiology, Chinese-German Stem Cell Center, the Key Laboratory of Drug Target Research and Pharmacodynamic Evaluation, Hubei Province, Huazhong University of Science and Technology, Wuhan, 430030, China.

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http://dx.doi.org/10.1007/s11596-016-1587-6DOI Listing
June 2016

Human Embryonic and Induced Pluripotent Stem Cell Based Toxicity Testing Models: Future Applications in New Drug Discovery.

Curr Med Chem 2016 ;23(30):3495-3509

Institute of Neurophysiology and Centre for Molecular Medicine Cologne (CMMC), Robert-Koch-Str. 39, 50931 Cologne, Germany.

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http://dx.doi.org/10.2174/0929867323666160627113436DOI Listing
February 2017

Generation of human induced pluripotent stem cell line from a patient with a long QT syndrome type 2.

Stem Cell Res 2016 Mar 6;16(2):304-7. Epub 2016 Jan 6.

Center for Physiology and Pathophysiology, Institute for Neurophysiology, Medical Faculty, University of Cologne, Cologne, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.scr.2015.12.039DOI Listing
March 2016

Conversion of Human Fibroblasts to Stably Self-Renewing Neural Stem Cells with a Single Zinc-Finger Transcription Factor.

Stem Cell Reports 2016 Apr 24;6(4):539-551. Epub 2016 Mar 24.

Department of Stem Cells and Developmental Biology, Cell Science Research Center, Royan Institute for Stem Cell Biology and Technology, ACECR, Tehran 1665659911, Iran; Department of Developmental Biology, University of Science and Culture, ACECR, Tehran 1461968151, Iran. Electronic address:

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http://dx.doi.org/10.1016/j.stemcr.2016.02.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4834053PMC
April 2016

The Potential Application of Biomaterials in Cardiac Stem Cell Therapy.

Curr Med Chem 2016 ;23(6):589-602

Institute for Neurophysiology and Center for Molecular Medicine Cologne (CMMC), University of Cologne, Robert-Koch-Str. 39, 50931, Cologne, Germany.

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http://dx.doi.org/10.2174/092986732306160303151041DOI Listing
November 2016

The Interaction between Adult Cardiac Fibroblasts and Embryonic Stem Cell-Derived Cardiomyocytes Leads to Proarrhythmic Changes in In Vitro Cocultures.

Stem Cells Int 2016 5;2016:2936126. Epub 2016 Jan 5.

Department of Paediatric Cardiology, Heart Centre Cologne, University Hospital of Cologne, Kerpener Strasse 62, 50937 Cologne, Germany; Institute for Neurophysiology, University of Cologne, Robert-Koch-Strasse 39, 50931 Cologne, Germany; Department of Paediatrics, University Hospital of Cologne, Kerpener Strasse 62, 50937 Cologne, Germany.

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http://dx.doi.org/10.1155/2016/2936126DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4736407PMC
February 2016

A differential impact of lithium on endothelium-dependent but not on endothelium-independent vessel relaxation.

Prog Neuropsychopharmacol Biol Psychiatry 2016 Jun 10;67:98-106. Epub 2016 Feb 10.

Institute of Physiology, Medical Faculty Carl Gustav Carus, Technical University of Dresden, Dresden, Germany.

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https://linkinghub.elsevier.com/retrieve/pii/S02785846163001
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http://dx.doi.org/10.1016/j.pnpbp.2016.02.004DOI Listing
June 2016

Beat Rate Variability in Murine Embryonic Stem Cell-Derived Cardiomyocytes: Effect of Antiarrhythmic Drugs.

Cell Physiol Biochem 2016 8;38(2):646-58. Epub 2016 Feb 8.

Department of Cardiology, University of Lx00FC;beck, Lx00FC;beck, Germany.

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http://dx.doi.org/10.1159/000438657DOI Listing
November 2016

MicroRNAs as early toxicity signatures of doxorubicin in human-induced pluripotent stem cell-derived cardiomyocytes.

Arch Toxicol 2016 Dec 3;90(12):3087-3098. Epub 2016 Feb 3.

Institute of Neurophysiology, Center for Molecular Medicine Cologne (CMMC), University of Cologne, 50931, Cologne, Germany.

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http://dx.doi.org/10.1007/s00204-016-1668-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5104806PMC
December 2016

Gene profiling of embryonic skeletal muscle lacking type I ryanodine receptor Ca(2+) release channel.

Sci Rep 2016 Feb 1;6:20050. Epub 2016 Feb 1.

Center of Physiology and Pathophysiology, Institute of Vegetative Physiology, Medical Faculty of the University of Cologne, Robert-Koch-Str. 39, Cologne 50931, Germany.

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http://dx.doi.org/10.1038/srep20050DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4735524PMC
February 2016

Transcriptomics of Hepatocytes Treated with Toxicants for Investigating Molecular Mechanisms Underlying Hepatotoxicity.

Methods Mol Biol 2015 ;1250:225-40

Center of Physiology and Pathophysiology, Institute of Neurophysiology, University of Cologne, Robert-Koch-Str. 39, 50931, Cologne, Germany.

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http://dx.doi.org/10.1007/978-1-4939-2074-7_16DOI Listing
May 2016

Low concentrations of ethanol but not of dimethyl sulfoxide (DMSO) impair reciprocal retinal signal transduction.

Graefes Arch Clin Exp Ophthalmol 2015 Oct 25;253(10):1713-9. Epub 2015 Jun 25.

Institute of Neurophysiology, University of Cologne, Robert-Koch-Str. 39, D-50931, Köln, Germany.

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http://dx.doi.org/10.1007/s00417-015-3070-7DOI Listing
October 2015

Docosahexaenoic acid alters Gsα localization in lipid raft and potentiates adenylate cyclase.

Nutrition 2015 Jul-Aug;31(7-8):1025-30. Epub 2015 Mar 17.

Department of Physiology, Chinese-German Stem Cell Center, Key Laboratory of Drug Target Research and Pharmacodynamic Evaluation, Hubei Province, School of Basic Medicine, Huazhong University of Science and Technology, Wuhan, China; The Institute of Brain Research, Huazhong University of Science and Technology, Wuhan, China; Tianjin Nankai Hospital, Tianjin, China. Electronic address:

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http://dx.doi.org/10.1016/j.nut.2015.02.012DOI Listing
May 2016

Calcium Imaging in Pluripotent Stem Cell-Derived Cardiac Myocytes.

Methods Mol Biol 2016 ;1353:131-46

Center for Physiology and Pathophysiology, Institute for Vegetative Physiology, Medical Faculty, University of Cologne, Robert-Koch-Str. 39, 50931, Cologne, Germany.

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http://dx.doi.org/10.1007/7651_2015_267DOI Listing
August 2016

Chromosome tracking in fused cells by single nucleotide polymorphisms.

Methods Mol Biol 2015 ;1313:95-106

Center for Physiology and Pathophysiology, Institute for Neurophysiology, Medical Faculty, University of Cologne, Robert Koch Str. 39, Cologne, 50931, Germany.

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http://dx.doi.org/10.1007/978-1-4939-2703-6_6DOI Listing
February 2016

Traditional Chinese medicine baicalin suppresses mESCs proliferation through inhibition of miR-294 expression.

Cell Physiol Biochem 2015 26;35(5):1868-76. Epub 2015 Mar 26.

Department of Physiology, Chinese-German Stem Cell Center, the Key Laboratory of Drug Target Research and Pharmacodynamic Evaluation, Hubei Province; School of Basic Medicine, Huazhong University of Science and Technology, Wuhan, China.

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December 2015

Voltage-gated calcium channels: Determinants of channel function and modulation by inorganic cations.

Prog Neurobiol 2015 Jun 25;129:1-36. Epub 2015 Mar 25.

Institute for Neurophysiology, University of Cologne, Robert-Koch-Str. 39, 50931 Cologne, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.pneurobio.2014.12.003DOI Listing
June 2015

Regionally diverse mitochondrial calcium signaling regulates spontaneous pacing in developing cardiomyocytes.

Cell Calcium 2015 May 18;57(5-6):321-36. Epub 2015 Feb 18.

Cardiac Signaling Center of USC, MUSC, & Clemson University, Charleston, SC, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ceca.2015.02.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4725313PMC
May 2015

Stem cells and differentiation--a synoptic review of patents granted since 2009.

Expert Opin Ther Pat 2015 Jun 2;25(6):663-73. Epub 2015 Mar 2.

University of Cologne, Institute of Neurophysiology and Center for Molecular Medicine Cologne (CMMC), Center of Physiology and Pathophysiology , Robert-Koch-Str 39, 50931, Cologne , Germany +49 0 221 478 7373 ; +49 0 221 478 6965 ;

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http://dx.doi.org/10.1517/13543776.2015.1021334DOI Listing
June 2015

In vitro chronotropic effects of Erythrina senegalensis DC (Fabaceae) aqueous extract on mouse heart slice and pluripotent stem cell-derived cardiomyocytes.

J Ethnopharmacol 2015 May 11;165:163-72. Epub 2015 Feb 11.

Institute of Neurophysiology, University of Cologne, 50931 Cologne, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.jep.2015.02.002DOI Listing
May 2015

Stem cell-derived systems in toxicology assessment.

Stem Cells Dev 2015 Jun 31;24(11):1284-96. Epub 2015 Mar 31.

19Division of Toxicology, Leiden Academic Centre for Drug Research, Leiden University, Leiden, the Netherlands.

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June 2015

Signaling molecules, transcription growth factors and other regulators revealed from in-vivo and in-vitro models for the regulation of cardiac development.

Int J Cardiol 2015 Mar 27;183:117-28. Epub 2015 Jan 27.

Center of Physiology and Pathophysiology, Institute of Neurophysiology and Center for Molecular Medicine Cologne (CMMC), University of Cologne, Germany. Electronic address:

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March 2015