Junya Fujimoto

Junya Fujimoto

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Junya Fujimoto

Junya Fujimoto

Publications by authors named "Junya Fujimoto"

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Development and Validation of a Pathology Image Analysis-based Predictive Model for Lung Adenocarcinoma Prognosis - A Multi-cohort Study.

Sci Rep 2019 May 3;9(1):6886. Epub 2019 May 3.

Quantitative Biomedical Research Center, Department of Clinical Sciences, University of Texas Southwestern Medical Center, Dallas, Texas, 75390, USA.

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http://dx.doi.org/10.1038/s41598-019-42845-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6499884PMC
May 2019

Genomic landscape of allelic imbalance in premalignant atypical adenomatous hyperplasias of the lung.

EBioMedicine 2019 Apr 21;42:296-303. Epub 2019 Mar 21.

Department of Epidemiology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA; The University of Texas MD Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences, Houston, TX, USA; Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ebiom.2019.03.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6491940PMC
April 2019

Genome-Wide and Phenotypic Evaluation of Stem Cell Progenitors Derived From -Deficient Murine Lung Adenocarcinoma With Somatic Mutations.

Front Oncol 2019 2;9:207. Epub 2019 Apr 2.

Department of Biochemistry and Molecular Genetics, Faculty of Medicine, American University of Beirut, Beirut, Lebanon.

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http://dx.doi.org/10.3389/fonc.2019.00207DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6454871PMC
April 2019

Randomized, Double-Blind, Phase II Study of Temozolomide in Combination With Either Veliparib or Placebo in Patients With Relapsed-Sensitive or Refractory Small-Cell Lung Cancer.

J Clin Oncol 2018 Aug 15;36(23):2386-2394. Epub 2018 Jun 15.

M. Catherine Pietanza, Lee M. Krug, Mark G. Kris, and Charles M. Rudin, Memorial Sloan-Kettering Cancer Center and Weill Cornell Medical College; Kaitlin M. Woo, Yevgeniva Bensman, Brenda Hurtado, and Martin Fleisher, Memorial Sloan Kettering Cancer Center, New York, NY; Saiama N. Waqar, Washington University School of Medicine in St. Louis, St Louis, MO; Afshin Dowlati, Case Western Reserve University and University Hospitals Seidman Cancer Center, Cleveland, OH; Christine L. Hann, Johns Hopkins University, Baltimore; Alice Chen, National Institutes of Health, Bethesda, MD; Alberto Chiappori, H. Lee Moffitt Cancer Center, Tampa, FL; Taofeek K. Owonikoko, Emory University, Atlanta, GA; and Robert J. Cardnell, Junya Fujimoto, Lihong Long, Lixia Diao, Jing Wang, Patricia de Groot, Erik P. Sulman, Ignacio I. Wistuba, John V. Heymach, and Lauren Averett Byers, The University of Texas MD Anderson Cancer Center, Houston, TX.

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http://dx.doi.org/10.1200/JCO.2018.77.7672DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6085179PMC
August 2018

Comprehensive analysis of lung cancer pathology images to discover tumor shape and boundary features that predict survival outcome.

Sci Rep 2018 Jul 10;8(1):10393. Epub 2018 Jul 10.

Quantitative Biomedical Research Center, Department of Clinical Sciences, University of Texas Southwestern Medical Center, Dallas, Texas, 75390, USA.

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http://dx.doi.org/10.1038/s41598-018-27707-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6039531PMC
July 2018

Spatial interaction of tumor cells and regulatory T cells correlates with survival in non-small cell lung cancer.

Lung Cancer 2018 03 4;117:73-79. Epub 2018 Feb 4.

Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX, 77030, USA; Experimental Radiation Oncology, The University of Texas MD Anderson Cancer Center,1515 Holcombe Boulevard, Houston, TX, 77030, USA. Electronic address:

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http://dx.doi.org/10.1016/j.lungcan.2018.01.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294443PMC
March 2018

Biomarker-Integrated Neoadjuvant Dasatinib Trial in Resectable Malignant Pleural Mesothelioma.

J Thorac Oncol 2018 02 5;13(2):246-257. Epub 2017 Dec 5.

Department of Thoracic/Head and Neck Medical Oncology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas.

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http://dx.doi.org/10.1016/j.jtho.2017.10.033DOI Listing
February 2018

RAD50 Expression Is Associated with Poor Clinical Outcomes after Radiotherapy for Resected Non-small Cell Lung Cancer.

Clin Cancer Res 2018 01 13;24(2):341-350. Epub 2017 Oct 13.

Department of Experimental Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.

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http://dx.doi.org/10.1158/1078-0432.CCR-17-1455DOI Listing
January 2018

Quantitative Proteomic Analysis of Optimal Cutting Temperature (OCT) Embedded Core-Needle Biopsy of Lung Cancer.

J Am Soc Mass Spectrom 2017 10 27;28(10):2078-2089. Epub 2017 Jul 27.

Department of Biochemistry, University of Texas Southwestern Medical Center, Dallas, TX, USA.

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http://dx.doi.org/10.1007/s13361-017-1706-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5693617PMC
October 2017

subfamily suppression in lung cancer pathogenesis: a high-potential marker for early detection.

Oncotarget 2017 Sep 4;8(40):68230-68241. Epub 2017 Aug 4.

Department of Biochemistry and Molecular Genetics, Faculty of Medicine, American University of Beirut, Beirut, Lebanon.

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http://dx.doi.org/10.18632/oncotarget.19938DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5620251PMC
September 2017

Expression of PD-1 and PD-L1 in thymic epithelial neoplasms.

Mod Pathol 2017 06 10;30(6):826-833. Epub 2017 Mar 10.

Department of Pathology, MD Anderson Cancer Center, Houston, TX, USA.

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http://dx.doi.org/10.1038/modpathol.2017.6DOI Listing
June 2017

Spindle cell and pleomorphic ("sarcomatoid") carcinomas of the lung: an immunohistochemical analysis of 86 cases.

Hum Pathol 2017 01 25;59:1-9. Epub 2016 Aug 25.

Department of Pathology, MD Anderson Cancer Center, Houston, TX, 77030, USA.

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http://dx.doi.org/10.1016/j.humpath.2016.08.003DOI Listing
January 2017

LAPTM4B is associated with poor prognosis in NSCLC and promotes the NRF2-mediated stress response pathway in lung cancer cells.

Sci Rep 2015 Sep 7;5:13846. Epub 2015 Sep 7.

Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX, U.S.A.

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http://dx.doi.org/10.1038/srep13846DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4561374PMC
September 2015

Primary mediastinal seminomas: a comprehensive immunohistochemical study with a focus on novel markers.

Hum Pathol 2015 Mar 26;46(3):376-83. Epub 2014 Nov 26.

Department of Pathology, MD Anderson Cancer Center, Houston, TX 77030.

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http://dx.doi.org/10.1016/j.humpath.2014.11.009DOI Listing
March 2015

Thymic neuroendocrine tumors (paraganglioma and carcinoid tumors): a comparative immunohistochemical study of 46 cases.

Hum Pathol 2014 Dec 6;45(12):2463-70. Epub 2014 Sep 6.

Department of Pathology, MD Anderson Cancer Center, Houston, TX 77030.

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http://dx.doi.org/10.1016/j.humpath.2014.08.013DOI Listing
December 2014

ASCL1 is a lineage oncogene providing therapeutic targets for high-grade neuroendocrine lung cancers.

Proc Natl Acad Sci U S A 2014 Oct 29;111(41):14788-93. Epub 2014 Sep 29.

Hamon Center for Therapeutic Oncology Research, Simmons Comprehensive Cancer Center, and Pharmacology, Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX 75235;

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http://dx.doi.org/10.1073/pnas.1410419111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4205603PMC
October 2014

Copper transporter CTR1 expression and tissue platinum concentration in non-small cell lung cancer.

Lung Cancer 2014 Jul 22;85(1):88-93. Epub 2014 Apr 22.

Department of Experimental Therapeutics, The University of Texas M.D. Anderson Cancer Center, Houston, TX, USA.

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http://dx.doi.org/10.1016/j.lungcan.2014.04.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4090351PMC
July 2014

Current concepts on the molecular pathology of non-small cell lung carcinoma.

Semin Diagn Pathol 2014 Jul 12;31(4):306-13. Epub 2014 Jun 12.

Department of Translational Molecular Pathology, The University of Texas M.D. Anderson Cancer Center, Houston, Texas; Department of Thoracic/Head and Neck Medical Oncology, The University of Texas M.D. Anderson Cancer Center, Houston, Texas. Electronic address:

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http://dx.doi.org/10.1053/j.semdp.2014.06.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4190584PMC
July 2014

Elevated PDGFRB gene copy number gain is prognostic for improved survival outcomes in resected malignant pleural mesothelioma.

Ann Diagn Pathol 2014 Jun 20;18(3):140-5. Epub 2014 Feb 20.

Department of Thoracic and Head & Neck Medical Oncology, University of Texas M.D. Anderson Cancer Center, Houston, TX; Department of Pathology, University of Texas M.D. Anderson Cancer Center, Houston, TX.

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http://dx.doi.org/10.1016/j.anndiagpath.2014.02.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4136493PMC
June 2014

Phase I trial of cisplatin, pemetrexed, and imatinib mesylate in chemonaive patients with unresectable malignant pleural mesothelioma.

Clin Lung Cancer 2014 May 27;15(3):197-201. Epub 2013 Dec 27.

Department of Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5080907PMC
http://dx.doi.org/10.1016/j.cllc.2013.12.008DOI Listing
May 2014

Transcriptomic architecture of the adjacent airway field cancerization in non-small cell lung cancer.

J Natl Cancer Inst 2014 Mar 22;106(3):dju004. Epub 2014 Feb 22.

Affiliations of authors: Department of Translational Molecular Pathology (HK, JF, TM, MMG, C-WC, ZC, GM, IIW), Department of Thoracic/Head and Neck Medical Oncology (MK, WKH, IIW), Department of Pathology (NK, CM), Department of Bioinformatics (S-YY, LS, JW, KRC), University of Texas MD Anderson Cancer Center, Houston, TX; Section of Computational Medicine, Department of Medicine, Boston University, Boston, MA (ACG, AS).

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http://dx.doi.org/10.1093/jnci/dju004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3982778PMC
March 2014

Comparable molecular alterations in 4-nitroquinoline 1-oxide-induced oral and esophageal cancer in mice and in human esophageal cancer, associated with poor prognosis of patients.

In Vivo 2013 Jul-Aug;27(4):473-84

Department of Clinical Cancer Prevention, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3849809PMC
January 2014

Validation of a proliferation-based expression signature as prognostic marker in early stage lung adenocarcinoma.

Clin Cancer Res 2013 Nov 18;19(22):6261-71. Epub 2013 Sep 18.

Authors' Affiliations: Departments of Translational Molecular Pathology, Thoracic/Head and Neck, Pathology, and Thoracic and Cardiovascular Surgery, The University of Texas, MD Anderson Cancer Center, Houston, Texas; Myriad Genetics, Inc., Salt Lake City, Utah; and Istituto Europeo di Oncologia, Milan, Italy.

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http://dx.doi.org/10.1158/1078-0432.CCR-13-0596DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3834029PMC
November 2013

HER family receptor and ligand status in thymic carcinoma.

Lung Cancer 2012 Sep 20;77(3):515-21. Epub 2012 Jun 20.

Department of Pathology, MD Anderson Cancer Center, Houston, TX 77030, USA.

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http://ac.els-cdn.com/S0169500212003777/1-s2.0-S016950021200
Web Search
http://linkinghub.elsevier.com/retrieve/pii/S016950021200377
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http://dx.doi.org/10.1016/j.lungcan.2012.05.108DOI Listing
September 2012

Tissue platinum concentration and tumor response in non-small-cell lung cancer.

J Clin Oncol 2012 Sep 13;30(27):3345-52. Epub 2012 Aug 13.

The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, Unit 463, Houston, TX 77030, USA.

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http://dx.doi.org/10.1200/JCO.2011.40.8120DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3438232PMC
September 2012

Abnormalities of the TITF-1 lineage-specific oncogene in NSCLC: implications in lung cancer pathogenesis and prognosis.

Clin Cancer Res 2011 Apr 21;17(8):2434-43. Epub 2011 Jan 21.

Departmentsof Thoracic/Head and Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-10-1412DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3078948PMC
April 2011

Validation of a novel statistical model for assessing the synergy of combined-agent cancer chemoprevention.

Cancer Prev Res (Phila) 2010 Aug 27;3(8):917-28. Epub 2010 Jul 27.

Department of Thoracic/Head and Neck Medical Oncology, The University of Texas M.D. Anderson Cancer Center, Houston, 77030, USA.

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http://cancerpreventionresearch.aacrjournals.org/cgi/doi/10.
Publisher Site
http://dx.doi.org/10.1158/1940-6207.CAPR-10-0129DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3496745PMC
August 2010

Comparative functional genomics analysis of NNK tobacco-carcinogen induced lung adenocarcinoma development in Gprc5a-knockout mice.

PLoS One 2010 Jul 29;5(7):e11847. Epub 2010 Jul 29.

Department of Thoracic/Head and Neck Medical Oncology, University of Texas M.D. Anderson Cancer Center, Houston, Texas, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0011847PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2912294PMC
July 2010

A Gprc5a tumor suppressor loss of expression signature is conserved, prevalent, and associated with survival in human lung adenocarcinomas.

Neoplasia 2010 Jun;12(6):499-505

Department of Thoracic/Head and Neck Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, TX, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2887090PMC
http://dx.doi.org/10.1593/neo.10390DOI Listing
June 2010

Knockout of the tumor suppressor gene Gprc5a in mice leads to NF-kappaB activation in airway epithelium and promotes lung inflammation and tumorigenesis.

Cancer Prev Res (Phila) 2010 Apr 30;3(4):424-37. Epub 2010 Mar 30.

Department of Thoracic/Head and Neck Medical Oncology, The University of Texas M.D. Anderson Cancer Center, Houston, TX 77030, USA.

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http://dx.doi.org/10.1158/1940-6207.CAPR-10-0032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4678967PMC
April 2010

Identification of the retinoic acid-inducible Gprc5a as a new lung tumor suppressor gene.

J Natl Cancer Inst 2007 Nov 13;99(22):1668-82. Epub 2007 Nov 13.

Department of Thoracic/Head and Neck Medical Oncology, The University of Texas M. D. Anderson Cancer Center, Houston, TX 77030, USA.

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http://jnci.oxfordjournals.org/content/99/22/1668.full.pdf
Web Search
http://jnci.oxfordjournals.org/cgi/doi/10.1093/jnci/djm208
Publisher Site
http://dx.doi.org/10.1093/jnci/djm208DOI Listing
November 2007

Expression of thymidylate synthase, thymidine phosphorylase, dihydropyrimidine dehydrogenase, E2F-1, Bak, Bcl-X, and Bcl-2, and clinical outcomes for gastric cancer patients treated with bolus 5-fluorouracil.

Oncol Rep 2004 Jan;11(1):9-15

Division of Digestive Endoscopy and Gastrointestinal Oncology, National Cancer Center Hospital East (NCCHE), Chiba 277-8577, Japan.

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January 2004