Publications by authors named "Junwei Feng"

6 Publications

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[Clinical application of distal femoral patient-specific cutting guide based on knee CT and full-length X-ray film of lower extremities].

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi 2021 Feb;35(2):188-194

Department of Orthopedics, Sichuan Academy of Medical Science & Sichuan Provincial People's Hospital, Chengdu Sichuan, 610072, P.R.China.

Objective: To discuss the feasibility and accuracy of distal femoral patient-specific cutting guide in total knee arthroplasty (TKA) based on knee CT and full-length X-ray film of lower extremities.

Methods: Between July 2016 and February 2017, 20 patients with severe knee joint osteoarthritis planned to undergo primary TKA were selected as the research object. There were 9 males and 11 females; aged 53-84 years, with an average of 69.4 years. The body mass index was 22.1-31.0 kg/m , with an average of 24.8 kg/m . The preoperative range of motion (ROM) of the knee joint was (103.0±19.4)°, the pain visual analogue scale (VAS) score was 5.4±1.3, and the American Hospital of Special Surgery (HSS) score was 58.1±11.3. Before operation, a three-dimensional model of the knee joint was constructed based on the full-length X-ray film of lower extremities and CT of the knee joint. The distal femoral patient-specific cutting guide was designed and fabricated, and the thickness of the distal femoral osteotomy was determined by digital simulation. The thickness of the internal and external condyle of the distal femur osteotomy before operation and the actual thickness of the intraoperative osteotomy were compared. The intraoperative blood loss, postoperative drainage loss, and hidden blood loss were recorded. The ROM of knee joint, VAS score, and HSS score at 3 months after operation were recorded to evaluate effectiveness. The position of the coronal and sagittal plane of the distal femoral prosthesis were assessed by comparing the femoral mechanical-anatomical angle (FMAA), anatomical lateral distal femoral angle (aLDFA), mechanical femoral tibial angle (mFTA), distal femoral flexion angle (DFFA), femoral prosthesis flexion angle (FPFA), anatomical lateral femoral component angle (aLFC), and the angle of the femoral component and femoral shaft (α angle) between pre- and post-operation.

Results: TKA was successfully completed with the aid of the distal femoral patient-specific cutting guide. There was no significant difference between the thickness of the internal and lateral condyle of the distal femur osteotomy before operation and the actual thickness of the intraoperative osteotomy ( >0.05). All patients were followed up 3 months. All incisions healed by first intention, and there was no complications such as periarticular infection and deep vein thrombosis. Except for 1 patient who was not treated with tranexamic acid, the intraoperative blood loss of the rest 19 patients ranged from 30 to 150 mL, with an average of 73.2 mL; the postoperative drainage loss ranged from 20 to 500 mL, with an average of 154.5 mL; and the hidden blood loss ranged from 169.2 to 1 400.0 mL, with an average of 643.8 mL. At 3 months after operation, the ROM of the knee was (111.5±11.5)°, and there was no significant difference when compared with the preoperative one ( =-1.962, =0.065). The VAS score was 2.4±0.9 and HSS score was 88.2±7.5, showing significant differences when compared with the preoperative ones ( =7.248, =0.000; =-11.442, =0.000). Compared with the preoperative measurements, there was a significant difference in mFTA ( <0.05), and there was no significant difference in aLDFA, FMAA, or DFFA; compared with the preoperative plan, there was no significant difference in FPFA, aLFC, or α angle ( >0.05).

Conclusion: The use of distal femoral patient-specific cutting guide based on knee CT and full-length X-ray film of lower extremity can achieve precise osteotomy, improve coronal and sagittal limb alignment, reduce intraoperative blood loss, and obtain satisfactory short-term effectiveness.
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http://dx.doi.org/10.7507/1002-1892.202008113DOI Listing
February 2021

RINT1 is a new suppression target to reduce colon cancer cell growth, migration and invasion through regulating ZW10/NAG-1 expression.

Mol Cell Biochem 2020 Aug 4. Epub 2020 Aug 4.

Department of Pathology, Tangshan Gongren Hospital, Lubei District, No. 27 Wenhua Road, Tangshan, 063000, Hebei, China.

This study explored the function and mechanism of RAD50 interactor 1 (RINT1), Zeste white 10 (ZW10) or nonsteroidal anti-inflammatory drug-activated gene-1 (NAG-1) in cell growth of colon cancer. The mRNA expression of RINT1 was suppressed in patients with colon cancer. In addition, disease free survival (DFS) in colon cancer patients with high expression of RINT1, ZW10 and NAG-1 were promoted compared with colon cancer patients with low expression of RINT1, ZW10 and NAG-1. Over-expression of RINT1, ZW10 or NAG-1 reduced colon cancer cell growth, migration and invasion in vitro model. In contrast, down-regulation of RINT1, ZW10 or NAG-1 promoted colon cancer cell growth, migration and invasion in vitro model. Over-expression of RINT1 promoted while down-regulation of RINT1 suppressed ZW10 and NAG-1 expression. Following knockdown of ZW10 and NAG-1 protein expressions, RINT1 induced changes of colon cancer cell growth, migration and invasion were inhibited. Taken together, it is indicated that RINT1 is a new suppression target to reduce cell growth, migration and invasion of colon cancer by targeting ZW10/NAG-1.
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http://dx.doi.org/10.1007/s11010-020-03858-9DOI Listing
August 2020

Ce-Mn coordination polymer derived hierarchical/porous structured CeO-MnO for enhanced catalytic properties.

Nanoscale 2020 Aug;12(30):16381-16388

School of Chemistry and Chemical Engineering, University of Jinan, 250022, China.

Catalytic performance is largely dependent on how the structures/compositions of materials are designed. Herein, CeO2-MnOx binary oxide catalysts with a hierarchical/porous structure are prepared by a facile and efficient method, which involves the preparation of the hierarchical Ce-Mn coordination polymer (CPs) precursor, followed by a thermal treatment step. The obtained CeO2-MnOx catalysts not only well inherit the hierarchical structure of Ce-Mn CPs, but also possess porous and hollow features due to the removal of organic ligands and heterogeneous contraction during the calcination process. In addition, the effect of the Mn/Ce ratio is also studied to optimize catalytic performance. Specifically, the as-prepared CeO2-MnOx (5 : 5) catalyst exhibits excellent catalytic performance toward CO oxidation and selective catalytic reduction (SCR) of NO with NH3 at low temperatures. Based on the characterization results, we propose that the special hierarchical structure, high surface area, strong synergistic interaction between CeO2 and MnOx, and high content of active Ce3+, Mn4+ and Osurf are collectively responsible for its remarkable catalytic performance.
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http://dx.doi.org/10.1039/d0nr03028gDOI Listing
August 2020

Investigation of lightning ignition characteristics based on an impulse current generator.

Ecol Evol 2019 Dec 2;9(24):14234-14243. Epub 2019 Dec 2.

Safety Engineering Research Center School of Intelligent System Engineering Sun Yat-sen University Guangzhou China.

Lightning strike is an important ignition source of forest fires. Artificial lightning discharge is a method for studying lightning fires. However, there is not enough data on the ignition of combustible materials caused by artificial lightning discharge. Previous studies on lightning ignition have focused on the heating and ignition effects of long continuing current (LCC), but the function of the impulse current that occurs before the LCC has not been taken into account. In this paper, an impulse current generator of 8/20 μs was used to simulate the ignition effect of impulse current on conifer needle beds. Different current waveforms have different ignition characteristics. We compared five kinds of conifer needle beds. The average of the current needed to ignite the needle bed of (Ruprecht) Kuzeneva was the smallest, and the average of the breakdown voltage was the smallest for the needle bed of Lamb. The total energy input to the conifer needle beds was fitted as a multiple log-linear regression model. The heating energy proportion value varies with different bulk densities, current amplitudes, and moisture contents. Based on this data, the heating energy of the impulse current transferred to the needles can be predicted. This information in conjunction with previous research on LCC was used to derive a lightning ignition prediction model of the full waveform for conifer needle beds.
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http://dx.doi.org/10.1002/ece3.5855DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6953689PMC
December 2019

Synthesis, characterization and catalytic epoxidation properties of a new tellurotungstate(iv)-supported rhenium carbonyl derivative.

Dalton Trans 2019 Jan;48(2):628-634

Henan Key Laboratory of Polyoxometalate Chemistry, Institute of Molecular and Crystal Engineering, College of Chemistry and Chemical Engineering, Henan University, Kaifeng, Henan 475004, P. R. China.

A monomeric tellurotungstate(iv)-supported rhenium carbonyl derivative: Na2H2[(CH3)4N]6[Te2W20O70{Re(CO)3}2]·20H2O (1) has been successfully isolated and structurally characterized by single crystal X-ray diffraction crystallography, IR and UV-Vis spectroscopy, thermogravimetric analysis, etc. In particular, complex 1 could act as a efficient and reusable heterogeneous catalyst for selective epoxidation of various alkenes including different cycloalkenes, styrene derivatives, internal and long-chain alkenes. For example, cis-cyclooctene undergoes up to 98.2% conversion and >99% selectivity at 75 °C in acetonitrile with 30% H2O2 as an oxidant. Additionally, the electrocatalytic property of 1 for NO2- reduction was also investigated.
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http://dx.doi.org/10.1039/c8dt04195dDOI Listing
January 2019

Facile CO Cycloaddition to Epoxides by Using a Tetracarbonyl Metal Selenotungstate Derivate [{Mn(CO)}(SeWO)].

Inorg Chem 2018 Dec 14;57(23):14632-14643. Epub 2018 Nov 14.

Henan Key Laboratory of Polyoxometalate, Institute of Molecular and Crystal Engineering, College of Chemistry and Chemical Engineering , Henan University , Kaifeng , 475004 Henan , PR China.

A novel polyoxometalate cluster, i.e., NaH[(CH)N]{[Mn(CO)](SeWO)}·9HO (1), has been successfully synthesized under moderately acidic conditions. Compound 1 contains four electron-donating {Mn(CO)} organometallic entities, which are grafted over an unprecedented heteropolytungstate electron-acceptor group. Compound 1 was further structurally characterized by various physicochemical techniques like elemental analyses, inductively coupled plasma (ICP) analyses, IR and UV-vis spectroscopy, electrochemistry, and single-crystal X-ray diffraction, and so on. The polyoxoanion of 1 comprises a novel {SeW} fragment, which is obtained from molecular assembly of rare {SeW} and {SeW} species. Evaluation of the data from solution-state IR spectrum showed excellent agreement with the solid state IR spectrum, indicating the intact clusters in the CHCN/NaSO solvent. Also, negative electrospray ionization mass spectrometry (ESI-MS) was an alternative tool to verify the stability of 1 in the mixed solvent. Additionally, the resulting hybrid can act as a catalyst for cyclic carbonate formation from the reactants epoxides and CO under modest reaction conditions in conjunction with a 1-ethyl-1-methylpyrrolidinium bromide (2). The good activity can be substantiated due to the cooperative influence of polyoxoanion and Br ions. Complex 1 can also be easily recycled and reused three times without obvious decrease of catalytic activity.
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http://dx.doi.org/10.1021/acs.inorgchem.8b02321DOI Listing
December 2018