Junmin Peng

Junmin Peng

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Multimodal Imaging of Amyloid Plaques: Fusion of the Single-Probe Mass Spectrometry Image and Fluorescence Microscopy Image.

Anal Chem 2019 Oct 26;91(20):12882-12889. Epub 2019 Sep 26.

Department of Chemistry and Biochemistry , University of Oklahoma , Norman , Oklahoma 73019 , United States.

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http://dx.doi.org/10.1021/acs.analchem.9b02792DOI Listing
October 2019

Akt Phosphorylates NQO1 and Triggers its Degradation, Abolishing Its Antioxidative Activities in Parkinson's Disease.

J Neurosci 2019 Sep 29;39(37):7291-7305. Epub 2019 Jul 29.

Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, Georgia 30322,

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http://dx.doi.org/10.1523/JNEUROSCI.0625-19.2019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6759025PMC
September 2019

Corrigendum to "Metabolic switching in pluripotent stem cells reorganizes energy metabolism and subcellular organelles" [379 (2019) 55-64].

Exp Cell Res 2019 Aug 9;381(1):163. Epub 2019 May 9.

Department of Hematology, St. Jude Children's Research Hospital, Memphis, TN, USA. Electronic address:

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http://dx.doi.org/10.1016/j.yexcr.2019.05.002DOI Listing
August 2019

Circadian gene variants and the skeletal muscle circadian clock contribute to the evolutionary divergence in longevity across populations.

Genome Res 2019 08 27;29(8):1262-1276. Epub 2019 Jun 27.

Division of Developmental Biology, Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, USA.

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http://dx.doi.org/10.1101/gr.246884.118DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6673717PMC
August 2019

Regulation of MAGE-A3/6 by the CRL4-DCAF12 ubiquitin ligase and nutrient availability.

EMBO Rep 2019 Jul 24;20(7):e47352. Epub 2019 May 24.

Department of Cell and Molecular Biology, St. Jude Children's Research Hospital, Memphis, TN, USA.

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http://dx.doi.org/10.15252/embr.201847352DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6607007PMC
July 2019

ALS-FTLD-linked mutations of SQSTM1/p62 disrupt selective autophagy and NFE2L2/NRF2 anti-oxidative stress pathway.

Autophagy 2019 Jul 30:1-15. Epub 2019 Jul 30.

Department of Neurology, The Friedman Brain Institute, Icahn School of Medicine at Mount Sinai , New York , NY , USA.

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http://dx.doi.org/10.1080/15548627.2019.1644076DOI Listing
July 2019

A Key Role for the Ubiquitin Ligase UBR4 in Myofiber Hypertrophy in Drosophila and Mice.

Cell Rep 2019 Jul;28(5):1268-1281.e6

Division of Developmental Biology, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN 38105, USA; Department of Developmental Neurobiology, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN 38105, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2019.06.094DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6697171PMC
July 2019

Phosphatidic acid generated by PLD2 promotes the plasma membrane recruitment of IQGAP1 and neointima formation.

FASEB J 2019 Jun 27;33(6):6713-6725. Epub 2019 Feb 27.

Department of Integrative Biology and Pharmacology, The University of Texas Health Science Center at Houston, Houston, Texas, USA.

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http://dx.doi.org/10.1096/fj.201800390RRDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6529346PMC
June 2019

Metabolic switching in pluripotent stem cells reorganizes energy metabolism and subcellular organelles.

Exp Cell Res 2019 Jun 25;379(1):55-64. Epub 2019 Mar 25.

Department of Hematology, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN, 38105, USA. Electronic address:

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http://dx.doi.org/10.1016/j.yexcr.2019.03.028DOI Listing
June 2019

Regulation of gene expression by miR-144/451 during mouse erythropoiesis.

Blood 2019 Jun 10;133(23):2518-2528. Epub 2019 Apr 10.

Division of Hematology/Oncology, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA.

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http://www.bloodjournal.org/lookup/doi/10.1182/blood.2018854
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http://dx.doi.org/10.1182/blood.2018854604DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6557621PMC
June 2019

LKB1 orchestrates dendritic cell metabolic quiescence and anti-tumor immunity.

Cell Res 2019 May 25;29(5):391-405. Epub 2019 Mar 25.

Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN, 38105, USA.

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http://dx.doi.org/10.1038/s41422-019-0157-4DOI Listing
May 2019

ULK1 and ULK2 Regulate Stress Granule Disassembly Through Phosphorylation and Activation of VCP/p97.

Mol Cell 2019 05 9;74(4):742-757.e8. Epub 2019 Apr 9.

Department of Pathology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA; Department of Cell and Molecular Biology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2019.03.027DOI Listing
May 2019

Deep undepleted human serum proteome profiling toward biomarker discovery for Alzheimer's disease.

Clin Proteomics 2019 17;16:16. Epub 2019 Apr 17.

1Departments of Structural Biology and Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, TN 38105 USA.

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http://dx.doi.org/10.1186/s12014-019-9237-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472024PMC
April 2019

TET2 stabilization by 14-3-3 binding to the phosphorylated Serine 99 is deregulated by mutations in cancer.

Cell Res 2019 Mar 3;29(3):248-250. Epub 2019 Jan 3.

Laboratory of Epigenetics, Liver Cancer Institute, Zhongshan Hospital, and Institutes of Biomedical Sciences, Fudan University, Shanghai, 200032, China.

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http://www.nature.com/articles/s41422-018-0132-5
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http://dx.doi.org/10.1038/s41422-018-0132-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6460428PMC
March 2019

Differentiation of human pluripotent stem cells into neurons or cortical organoids requires transcriptional co-regulation by UTX and 53BP1.

Nat Neurosci 2019 03 4;22(3):362-373. Epub 2019 Feb 4.

Department of Developmental Neurobiology and Division of Developmental Biology, St. Jude Children's Research Hospital, Memphis, TN, USA.

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http://dx.doi.org/10.1038/s41593-018-0328-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6511450PMC
March 2019

Deubiquitylase USP9X maintains centriolar satellite integrity by stabilizing pericentriolar material 1 protein.

J Cell Sci 2019 01 22;132(2). Epub 2019 Jan 22.

Department of Biochemistry and Molecular Genetics, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA

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http://dx.doi.org/10.1242/jcs.221663DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6362394PMC
January 2019

Epidithiodiketopiperazines Inhibit Protein Degradation by Targeting Proteasome Deubiquitinase Rpn11.

Cell Chem Biol 2018 11 23;25(11):1350-1358.e9. Epub 2018 Aug 23.

Division of Biology and Biological Engineering, California Institute of Technology, Box 114-96, Pasadena, CA 91125, USA; Howard Hughes Medical Institute, Chevy Chase, MD 26335, USA; Amgen Discovery Research, One Amgen Center Drive MS 29-M-B, Thousand Oaks, CA 91320, USA. Electronic address:

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http://dx.doi.org/10.1016/j.chembiol.2018.07.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6309308PMC
November 2018

Deep Profiling of the Aggregated Proteome in Alzheimer's Disease: From Pathology to Disease Mechanisms.

Proteomes 2018 Nov 12;6(4). Epub 2018 Nov 12.

Departments of Structural Biology and Developmental Neurobiology, Center for Proteomics and Metabolomics, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.

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http://dx.doi.org/10.3390/proteomes6040046DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6313861PMC
November 2018

Spectral Library Search Improves Assignment of TMT Labeled MS/MS Spectra.

J Proteome Res 2018 09 16;17(9):3325-3331. Epub 2018 Aug 16.

Department of Computer Science , University of Waterloo , Waterloo , Ontario N2L 3G1 , Canada.

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http://dx.doi.org/10.1021/acs.jproteome.8b00594DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390480PMC
September 2018

Identification of Therapeutic Targets in Rhabdomyosarcoma through Integrated Genomic, Epigenomic, and Proteomic Analyses.

Cancer Cell 2018 09 23;34(3):411-426.e19. Epub 2018 Aug 23.

Department of Developmental Neurobiology, St. Jude Children's Research Hospital, 262 Danny Thomas Place, MS 323, Memphis, TN 38105-3678, USA; Department of Ophthalmology, University of Tennessee Health Science Center, Memphis, TN 38105, USA; Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2018.07.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6158019PMC
September 2018

Mutant LRRK2 mediates peripheral and central immune responses leading to neurodegeneration in vivo.

Brain 2018 06;141(6):1753-1769

Department of Developmental Neurobiology, St. Jude Children's Research Hospital, 262 Danny Thomas Blvd, Memphis TN 38105, USA.

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http://dx.doi.org/10.1093/brain/awy077DOI Listing
June 2018

Quantitative Phosphoproteomic Analysis of Brain Tissues.

Methods Mol Biol 2017 ;1598:199-211

Department of Structural Biology, St. Jude Children's Research Hospital, MS 311, D1034C, 262 Danny Thomas Place, Memphis, TN, 38105-3678, USA.

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http://dx.doi.org/10.1007/978-1-4939-6952-4_8DOI Listing
March 2018

Deep Proteome Profiling by Isobaric Labeling, Extensive Liquid Chromatography, Mass Spectrometry, and Software-assisted Quantification.

J Vis Exp 2017 11 15(129). Epub 2017 Nov 15.

St. Jude Proteomics Facility, St. Jude Children's Research Hospital; Departments of Structural Biology and Developmental Neurobiology, St. Jude Children's Research Hospital;

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http://dx.doi.org/10.3791/56474DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5755397PMC
November 2017

Binding of PLD2-Generated Phosphatidic Acid to KIF5B Promotes MT1-MMP Surface Trafficking and Lung Metastasis of Mouse Breast Cancer Cells.

Dev Cell 2017 10 12;43(2):186-197.e7. Epub 2017 Oct 12.

Department of Integrative Biology and Pharmacology, University of Texas Health Science Center at Houston, 6431 Fannin St., Houston, TX 77030, USA. Electronic address:

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http://dx.doi.org/10.1016/j.devcel.2017.09.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663201PMC
October 2017

The neoepitope landscape in pediatric cancers.

Genome Med 2017 08 31;9(1):78. Epub 2017 Aug 31.

Department of Computational Biology, St Jude Children's Research Hospital, Memphis, Tennessee, 38105, USA.

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http://dx.doi.org/10.1186/s13073-017-0468-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5577668PMC
August 2017

Targeting human Mas-related G protein-coupled receptor X1 to inhibit persistent pain.

Proc Natl Acad Sci U S A 2017 03 21;114(10):E1996-E2005. Epub 2017 Feb 21.

The Solomon H. Snyder Department of Neuroscience, Center for Sensory Biology, Johns Hopkins University School of Medicine, Baltimore, MD 21205;

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http://dx.doi.org/10.1073/pnas.1615255114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5347560PMC
March 2017

The C. elegans Taste Receptor Homolog LITE-1 Is a Photoreceptor.

Cell 2016 11;167(5):1252-1263.e10

Life Sciences Institute and Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI 48109, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2016.10.053DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5388352PMC
November 2016

C9orf72 Dipeptide Repeats Impair the Assembly, Dynamics, and Function of Membrane-Less Organelles.

Cell 2016 Oct;167(3):774-788.e17

Department of Cell and Molecular Biology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA; Howard Hughes Medical Institute, Department of Cell and Molecular Biology, St Jude Children's Research Hospital, Memphis, TN 38105, USA. Electronic address:

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5079111PMC
http://dx.doi.org/10.1016/j.cell.2016.10.002DOI Listing
October 2016

SUMO Pathway Modulation of Regulatory Protein Binding at the Ribosomal DNA Locus in Saccharomyces cerevisiae.

Genetics 2016 Apr 2;202(4):1377-94. Epub 2016 Feb 2.

Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, Connecticut 06520-8114

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http://dx.doi.org/10.1534/genetics.116.187252DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905256PMC
April 2016

Enhanced Purification of Ubiquitinated Proteins by Engineered Tandem Hybrid Ubiquitin-binding Domains (ThUBDs).

Mol Cell Proteomics 2016 Apr;15(4):1381-96

From the ‡State Key Laboratory of Proteomics, National Engineering Research Center for Protein Drugs, Beijing Proteome Research Center, National Center for Protein Sciences Beijing, Beijing Institute of Radiation Medicine, Beijing 102206,China; the ¶School of Basic Medical Science, Key Laboratory of Combinatorial Biosynthesis and Drug Discovery of Ministry of Education, School of Pharmaceutical Sciences, Wuhan University, Wuhan 430071, China;

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http://dx.doi.org/10.1074/mcp.o115.051839DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4824862PMC
April 2016

Multiple Weak Linear Motifs Enhance Recruitment and Processivity in SPOP-Mediated Substrate Ubiquitination.

J Mol Biol 2016 Mar 22;428(6):1256-1271. Epub 2015 Oct 22.

Department of Structural Biology, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN 38105, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jmb.2015.10.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4826287PMC
March 2016

Quantitative protein analysis by mass spectrometry.

Methods Mol Biol 2015 ;1278:281-305

St. Jude Proteomics Facility, St. Jude Children's Research Hospital, Memphis, TN, 38105, USA.

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http://dx.doi.org/10.1007/978-1-4939-2425-7_17DOI Listing
December 2015

A Degenerate Cohort of Yeast Membrane Trafficking DUBs Mediates Cell Polarity and Survival.

Mol Cell Proteomics 2015 Dec 27;14(12):3132-41. Epub 2015 Sep 27.

From the Cell & Developmental Biology, Vanderbilt University School of Medicine, 1161 21st Avenue South, Nashville, TN 37232

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http://dx.doi.org/10.1074/mcp.M115.050039DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4762628PMC
December 2015

Global ubiquitination analysis by SILAC in mammalian cells.

Methods Mol Biol 2014 ;1188:149-60

Department of Structural Biology, St. Jude Proteomics Facility, St Jude Children's Research Hospital, Memphis, TN, 38105, USA.

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http://dx.doi.org/10.1007/978-1-4939-1142-4_11DOI Listing
March 2015

Systematic optimization of long gradient chromatography mass spectrometry for deep analysis of brain proteome.

J Proteome Res 2015 Feb 12;14(2):829-38. Epub 2014 Dec 12.

Department of Structural Biology, ‡St. Jude Proteomics Facility, and §̂Department of Developmental Neurobiology, St. Jude Children's Research Hospital , 262 Danny Thomas Place, Memphis, Tennessee 38105, United States.

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http://dx.doi.org/10.1021/pr500882hDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4324436PMC
February 2015

Refined phosphopeptide enrichment by phosphate additive and the analysis of human brain phosphoproteome.

Proteomics 2015 Jan 15;15(2-3):500-7. Epub 2014 Dec 15.

St. Jude Proteomics Facility, St. Jude Children's Research Hospital, Memphis, TN, USA.

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http://doi.wiley.com/10.1002/pmic.201400171
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http://dx.doi.org/10.1002/pmic.201400171DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4598062PMC
January 2015

Altered ubiquitin causes perturbed calcium homeostasis, hyperactivation of calpain, dysregulated differentiation, and cataract.

Proc Natl Acad Sci U S A 2015 Jan 12;112(4):1071-6. Epub 2015 Jan 12.

Laboratory for Nutrition and Vision Research, US Department of Agriculture Human Nutrition Research Center on Aging, Tufts University, Boston, MA 02111; Department of Biological Chemistry, Weizmann Institute of Science, Rehovot 7610001, Israel

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http://dx.doi.org/10.1073/pnas.1404059112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4313858PMC
January 2015

JUMP: a tag-based database search tool for peptide identification with high sensitivity and accuracy.

Mol Cell Proteomics 2014 Dec 8;13(12):3663-73. Epub 2014 Sep 8.

From the ‡St. Jude Proteomics Facility, St. Jude Children's Research Hospital, Memphis, Tennessee 38105; §Departments of Structural Biology and Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, Tennessee 38105;

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http://dx.doi.org/10.1074/mcp.O114.039586DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4256513PMC
December 2014

Integrated approaches for analyzing U1-70K cleavage in Alzheimer's disease.

J Proteome Res 2014 Nov 13;13(11):4526-34. Epub 2014 Jun 13.

Departments of Structural Biology and Developmental Neurobiology, ‡St. Jude Proteomics Facility, St. Jude Children's Research Hospital , Memphis, Tennessee 38105, United States.

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http://dx.doi.org/10.1021/pr5003593DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4227550PMC
November 2014

Autoregulation of the 26S proteasome by in situ ubiquitination.

Mol Biol Cell 2014 Jun 17;25(12):1824-35. Epub 2014 Apr 17.

Department of Biochemistry and Molecular Genetics, University of Colorado School of Medicine, Aurora, CO 80045

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http://dx.doi.org/10.1091/mbc.E13-10-0585DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4055262PMC
June 2014

A nano ultra-performance liquid chromatography-high resolution mass spectrometry approach for global metabolomic profiling and case study on drug-resistant multiple myeloma.

Anal Chem 2014 Apr 20;86(7):3667-75. Epub 2014 Mar 20.

Departments of †Structural Biology and Developmental Neurobiology and ‡St. Jude Proteomics Facility, St. Jude Children's Research Hospital , 262 Danny Thomas Place, Memphis, Tennessee 38105, United States.

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http://dx.doi.org/10.1021/ac500476aDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6424491PMC
April 2014

The U4/U6 recycling factor SART3 has histone chaperone activity and associates with USP15 to regulate H2B deubiquitination.

J Biol Chem 2014 Mar 13;289(13):8916-30. Epub 2014 Feb 13.

From the Department of Biochemistry and Molecular Biology, Colorado State University, Fort Collins, Colorado 80523.

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http://dx.doi.org/10.1074/jbc.M114.551754DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3979369PMC
March 2014

Identification and characterization of phosphorylation sites within the pregnane X receptor protein.

Biochem Pharmacol 2014 Jan 30;87(2):360-70. Epub 2013 Oct 30.

Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN 38105, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00062952130068
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http://dx.doi.org/10.1016/j.bcp.2013.10.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3947193PMC
January 2014

Structural insights into the functions of TBK1 in innate antimicrobial immunity.

Structure 2013 Jul 6;21(7):1137-48. Epub 2013 Jun 6.

Department of Biochemistry and Biophysics, Texas A&M University, College Station, TX 77843-2128, USA.

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http://dx.doi.org/10.1016/j.str.2013.04.025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3702631PMC
July 2013

Proteomic analysis of postsynaptic density in Alzheimer's disease.

Clin Chim Acta 2013 May 26;420:62-8. Epub 2013 Mar 26.

St. Jude Children's Research Hospital, Memphis, TN 38105-3678, United States.

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http://dx.doi.org/10.1016/j.cca.2013.03.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3714371PMC
May 2013

Sjogren syndrome antigen B (SSB)/La promotes global microRNA expression by binding microRNA precursors through stem-loop recognition.

J Biol Chem 2013 Jan 5;288(1):723-36. Epub 2012 Nov 5.

Department of Biochemistry, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.

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http://dx.doi.org/10.1074/jbc.M112.401323DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3537071PMC
January 2013

Characterizing ubiquitination sites by peptide-based immunoaffinity enrichment.

Mol Cell Proteomics 2012 Dec 23;11(12):1529-40. Epub 2012 Jun 23.

Department of Protein Chemistry, Genentech, Inc., South San Francisco, California 94080, USA.

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http://dx.doi.org/10.1074/mcp.R112.019117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3518114PMC
December 2012

Ubiquitin-specific protease 9x deubiquitinates and stabilizes the spinal muscular atrophy protein-survival motor neuron.

J Biol Chem 2012 Dec 30;287(52):43741-52. Epub 2012 Oct 30.

Department of Biochemistry and Molecular Genetics, University of Colorado School of Medicine, Aurora, Colorado 80045, USA.

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http://dx.doi.org/10.1074/jbc.M112.372318DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3527959PMC
December 2012

The F-box protein FBXO44 mediates BRCA1 ubiquitination and degradation.

J Biol Chem 2012 Nov 18;287(49):41014-22. Epub 2012 Oct 18.

Department of Molecular Medicine, Institute of Biotechnology, University of Texas Health Science Center at San Antonio, San Antonio, Texas 78229, USA.

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http://dx.doi.org/10.1074/jbc.M112.407106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3510804PMC
November 2012

Analysis of ubiquitinated proteome by quantitative mass spectrometry.

Methods Mol Biol 2012 ;893:417-29

Department of Structural Biology, St. Jude Children's Research Hospital, Memphis, TN, USA.

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http://dx.doi.org/10.1007/978-1-61779-885-6_26DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3467951PMC
September 2012

Quantitative proteomics to decipher ubiquitin signaling.

Amino Acids 2012 Sep 22;43(3):1049-60. Epub 2012 Jul 22.

Departments of Structural Biology and Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.

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http://link.springer.com/10.1007/s00726-012-1286-y
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http://dx.doi.org/10.1007/s00726-012-1286-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3498854PMC
September 2012

Stable isotope labeling with amino acids in Drosophila for quantifying proteins and modifications.

J Proteome Res 2012 Sep 10;11(9):4403-12. Epub 2012 Aug 10.

Department of Human Genetics, Center for Neurodegenerative Diseases, Emory University School of Medicine, Atlanta, Georgia 30322, USA.

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http://dx.doi.org/10.1021/pr300613cDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3443408PMC
September 2012

Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis.

J Proteome Res 2012 Sep 15;11(9):4722-32. Epub 2012 Aug 15.

Departments of Structural Biology and Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, USA.

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http://dx.doi.org/10.1021/pr300536kDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3443409PMC
September 2012

Asparaginyl endopeptidase cleaves TDP-43 in brain.

Proteomics 2012 Aug;12(15-16):2455-63

Department of Neurology, Center for Neurodegenerative Diseases, Emory University School of Medicine, Atlanta, GA 30322, USA.

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http://dx.doi.org/10.1002/pmic.201200006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3787696PMC
August 2012

PHD3-dependent hydroxylation of HCLK2 promotes the DNA damage response.

J Clin Invest 2012 Aug 17;122(8):2827-36. Epub 2012 Jul 17.

UNC McAllister Heart Institute and Department of Medicine, University of North Carolina, Chapel Hill, NC, USA.

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http://www.jci.org/articles/view/62374
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http://dx.doi.org/10.1172/JCI62374DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3408739PMC
August 2012

Altered sodium channel-protein associations in critical illness myopathy.

Skelet Muscle 2012 Aug 30;2(1):17. Epub 2012 Aug 30.

Department of Neuroscience, Cell Biology, and Physiology, Wright State University School of Medicine, 3640 Colonel Glenn Hwy, Dayton, OH, 45435, USA.

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http://dx.doi.org/10.1186/2044-5040-2-17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3441911PMC
August 2012

Regulation of behavioral circadian rhythms and clock protein PER1 by the deubiquitinating enzyme USP2.

Biol Open 2012 Aug 28;1(8):789-801. Epub 2012 Jun 28.

Polypeptide Laboratory, Department of Medicine, McGill University and McGill University Health Centre Research Institute , Montréal, QC H3A 2B2 , Canada.

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http://dx.doi.org/10.1242/bio.20121990DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3507220PMC
August 2012

Deciphering tissue-specific ubiquitylation by mass spectrometry.

Methods Mol Biol 2012 ;832:65-80

Ikerbasque, Basque Foundation for Science, Bilbao, Spain.

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http://dx.doi.org/10.1007/978-1-61779-474-2_3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3475722PMC
July 2012

Desumoylation of the endoplasmic reticulum membrane VAP family protein Scs2 by Ulp1 and SUMO regulation of the inositol synthesis pathway.

Mol Cell Biol 2012 Jan 24;32(1):64-75. Epub 2011 Oct 24.

Departments of Molecular, Cell, & Developmental Biology, Yale University, New Haven, Connecticut, USA.

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http://mcb.asm.org/cgi/doi/10.1128/MCB.05878-11
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http://dx.doi.org/10.1128/MCB.05878-11DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3255706PMC
January 2012

SOX4 interacts with plakoglobin in a Wnt3a-dependent manner in prostate cancer cells.

BMC Cell Biol 2011 Nov 19;12:50. Epub 2011 Nov 19.

Department of Pathology & Laboratory Medicine, Emory University School of Medicine, Atlanta, GA 30322, USA.

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http://dx.doi.org/10.1186/1471-2121-12-50DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3227594PMC
November 2011

Protein Cysteines Map to Functional Networks According to Steady-state Level of Oxidation.

J Proteomics Bioinform 2011 Oct;4(10):196-209

Division of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, Emory Proteomics Service Center, Emory University, Atlanta, Georgia 30322 USA.

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http://dx.doi.org/10.4172/jpb.1000190DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3352318PMC
October 2011

Proteomics of gliomas: initial biomarker discovery and evolution of technology.

Neuro Oncol 2011 Sep;13(9):926-42

Laboratory of Molecular Neuro-Oncology, Departments of Neurosurgery, Hematology and Medical Oncology, School of Medicine, and Winship Cancer Institute, Emory University, Atlanta, GA 30322, USA.

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http://dx.doi.org/10.1093/neuonc/nor078DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3158015PMC
September 2011

Structural basis of SETD6-mediated regulation of the NF-kB network via methyl-lysine signaling.

Nucleic Acids Res 2011 Aug 22;39(15):6380-9. Epub 2011 Apr 22.

Department of Biochemistry, Emory University School of Medicine, 1510 Clifton Road, Atlanta, GA 30322, USA.

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http://dx.doi.org/10.1093/nar/gkr256DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3159447PMC
August 2011

Nuclear accumulation of stress response mRNAs contributes to the neurodegeneration caused by Fragile X premutation rCGG repeats.

PLoS Genet 2011 Jun 2;7(6):e1002102. Epub 2011 Jun 2.

Department of Human Genetics, Emory University School of Medicine, Atlanta, Georgia, USA.

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http://dx.doi.org/10.1371/journal.pgen.1002102DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3107199PMC
June 2011