Dr. Junmei Cairns, PhD - Mayo Clinic

Dr. Junmei Cairns

PhD

Mayo Clinic

Mn | United States

ORCID logohttps://orcid.org/0000-0002-3941-4564

Dr. Junmei Cairns, PhD - Mayo Clinic

Dr. Junmei Cairns

PhD

Introduction

Primary Affiliation: Mayo Clinic - Mn , United States

Education

Jul 2009 - Sep 2016
Mayo Clinic College of Medicine
Post Doctoral training
Department of Molecular Pharmacology and Experimental Therapeutics
Jul 2003 - Jul 2009
Shanghai Institutes for Biological Sciences
PhD
Jul 1999 - Jul 2003
Harbin Institute of Technology
BS

Experience

Oct 2016
Mayo Clinic
Research Scientist/Assistant professor
Department of Molecular Pharmacology and Experimental Therapeutics

Publications

22Publications

269Reads

1Profile Views

173PubMed Central Citations

The lncRNA MIR2052HG regulates ERα levels and aromatase inhibitor resistance through LMTK3 by recruiting EGR1.

Breast Cancer Res 2019 04 3;21(1):47. Epub 2019 Apr 3.

Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN, 55905, USA.

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http://dx.doi.org/10.1186/s13058-019-1130-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6448248PMC
April 2019
3 Reads

Identification of pathways associated with chemosensitivity through network embedding.

PLoS Comput Biol 2019 03 20;15(3):e1006864. Epub 2019 Mar 20.

Department of Computer Science, University of Illinois at Urbana-Champaign, Urbana, Illinois, United States of America.

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http://dx.doi.org/10.1371/journal.pcbi.1006864DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6443184PMC
March 2019
2 Reads

Principled multi-omic analysis reveals gene regulatory mechanisms of phenotype variation.

Genome Res 2018 08 13;28(8):1207-1216. Epub 2018 Jun 13.

Department of Computer Science and Institute of Genomic Biology, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, USA.

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http://dx.doi.org/10.1101/gr.227066.117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6071639PMC
August 2018
3 Reads
14.630 Impact Factor

Differential roles of ERRFI1 in EGFR and AKT pathway regulation affect cancer proliferation.

EMBO Rep 2018 03 15;19(3). Epub 2018 Jan 15.

Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN, USA

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http://dx.doi.org/10.15252/embr.201744767DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5835844PMC
March 2018
2 Reads
9.055 Impact Factor

SNPs near the cysteine proteinase cathepsin O gene (CTSO) determine tamoxifen sensitivity in ERα-positive breast cancer through regulation of BRCA1.

PLoS Genet 2017 Oct 2;13(10):e1007031. Epub 2017 Oct 2.

Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, Minnesota, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1007031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5638617PMC
October 2017
15 Reads
2 Citations

Knowledge-guided gene prioritization reveals new insights into the mechanisms of chemoresistance.

Genome Biol 2017 08 11;18(1):153. Epub 2017 Aug 11.

Department of Computer Science and Institute of Genomic Biology, University of Illinois at Urbana-Champaign, 2122 Siebel Center, 201N. Goodwin Ave, Urbana, IL, 61801, USA.

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http://dx.doi.org/10.1186/s13059-017-1282-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5554409PMC
August 2017
41 Reads
1 Citation

Model-based unsupervised learning informs metformin-induced cell-migration inhibition through an AMPK-independent mechanism in breast cancer.

Oncotarget 2017 Apr;8(16):27199-27215

Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN, USA.

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http://dx.doi.org/10.18632/oncotarget.16109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5432329PMC
April 2017
5 Reads
1 Citation
6.360 Impact Factor

A network-based phenotype mapping approach to identify genes that modulate drug response phenotypes.

Sci Rep 2016 11 14;6:37003. Epub 2016 Nov 14.

Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic College of Medicine, Rochester, MN 55905, USA.

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http://dx.doi.org/10.1038/srep37003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5107984PMC
November 2016
19 Reads
2 Citations
5.080 Impact Factor

Computational discovery of transcription factors associated with drug response.

Pharmacogenomics J 2016 11 27;16(6):573-582. Epub 2015 Oct 27.

Department of Computer Science and Institute of Genomic Biology, University of Illinois at Urbana-Champaign, Urbana, IL, USA.

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http://dx.doi.org/10.1038/tpj.2015.74DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4848185PMC
November 2016
2 Citations
4.230 Impact Factor

Bora downregulation results in radioresistance by promoting repair of double strand breaks.

PLoS One 2015 5;10(3):e0119208. Epub 2015 Mar 5.

Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, Minnesota, 55905, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0119208PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4351037PMC
January 2016
20 Reads
1 Citation
3.234 Impact Factor

FKBP5 as a selection biomarker for gemcitabine and Akt inhibitors in treatment of pancreatic cancer.

PLoS One 2012 9;7(5):e36252. Epub 2012 May 9.

Division of Clinical Pharmacology, Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, Minnesota, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0036252PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3348935PMC
September 2012
3 Reads
13 Citations
3.234 Impact Factor

Iron deprivation suppresses hepatocellular carcinoma growth in experimental studies.

Clin Cancer Res 2011 Dec 3;17(24):7625-33. Epub 2011 Nov 3.

Key Laboratory of Nutrition and Metabolism, Institute for Nutritional Sciences, Shanghai, China.

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http://dx.doi.org/10.1158/1078-0432.CCR-10-3099DOI Listing
December 2011
5 Reads
15 Citations
8.722 Impact Factor

Radiation pharmacogenomics: a genome-wide association approach to identify radiation response biomarkers using human lymphoblastoid cell lines.

Genome Res 2010 Nov 5;20(11):1482-92. Epub 2010 Oct 5.

Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, Minnesota 55905, USA.

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http://dx.doi.org/10.1101/gr.107672.110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2963812PMC
November 2010
14 Reads
74 Citations
14.630 Impact Factor

Experimental therapy of hepatoma with artemisinin and its derivatives: in vitro and in vivo activity, chemosensitization, and mechanisms of action.

Clin Cancer Res 2008 Sep;14(17):5519-30

Key Laboratory of Nutrition and Metabolism, Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences; Graduate School of the Chinese Academy of Sciences, Shanghai 200031, People's Republic of China.

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http://dx.doi.org/10.1158/1078-0432.CCR-08-0197DOI Listing
September 2008
6 Reads
54 Citations
8.722 Impact Factor

Top co-authors

Liewei Wang
Liewei Wang

Mayo Clinic

18
Krishna R Kalari
Krishna R Kalari

Mayo Clinic

9
Richard M Weinshilboum
6
James N Ingle
James N Ingle

Mayo Clinic

5
Erin E Carlson
Erin E Carlson

Indiana University

4
Matthew P Goetz
Matthew P Goetz

Mayo Clinic

4
Richard Weinshilboum
Richard Weinshilboum

Mayo Clinic

4
Poulami Barman
Poulami Barman

Mayo Clinic

4
Junmei Hou
Junmei Hou

Institute for Nutritional Sciences

4
Michiaki Kubo
Michiaki Kubo

RIKEN Center for Integrative Medical Sciences

4