Junichi Kikuta

Junichi Kikuta

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Junichi Kikuta

Publications by authors named "Junichi Kikuta"

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Multicolor Imaging with Fluorescent Probes Revealed the Dynamics and Function of Osteoclast Proton Pumps.

ACS Cent Sci 2019 Jun 1;5(6):1059-1066. Epub 2019 May 1.

Department of Material and Life Science, Graduate School of Engineering, Osaka University, Suita, Osaka 565-0871, Japan.

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http://dx.doi.org/10.1021/acscentsci.9b00220DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6598158PMC
June 2019

Imaging the Bone-Immune Cell Interaction in Bone Destruction.

Front Immunol 2019 26;10:596. Epub 2019 Mar 26.

Department of Immunology and Cell Biology, Graduate School of Medicine and Frontier Biosciences, Osaka University, Osaka, Japan.

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http://dx.doi.org/10.3389/fimmu.2019.00596DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6443987PMC
March 2019

Bone Imaging: Osteoclast and Osteoblast Dynamics.

Methods Mol Biol 2018 ;1763:1-9

Department of Immunology and Cell Biology, Graduate School of Medicine, Osaka University, Osaka, Japan.

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http://dx.doi.org/10.1007/978-1-4939-7762-8_1DOI Listing
February 2019

Intravital Imaging of Liver Cell Dynamics.

Methods Mol Biol 2018 ;1763:137-143

Department of Immunology and Cell Biology, Graduate School of Medicine, Osaka University, Osaka, Japan.

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http://dx.doi.org/10.1007/978-1-4939-7762-8_13DOI Listing
February 2019

Intravital Imaging of the Heart at the Cellular Level Using Two-Photon Microscopy.

Methods Mol Biol 2018 ;1763:145-151

Department of Cardiovascular Surgery, Osaka University Graduate School of Medicine, Osaka, Japan.

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http://dx.doi.org/10.1007/978-1-4939-7762-8_14DOI Listing
February 2019

[Homeostasis and Disorder of Musculoskeletal System.Cellular dynamics in musculoskeletal system visualized by intravital imaging techniques.]

Clin Calcium 2018;28(3):367-371

Department of Immunology and Cell Biology, Graduate School of Medicine and Frontier Biosciences, Osaka University, Japan.

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http://dx.doi.org/CliCa1803367371DOI Listing
February 2019

Dynamic Analyses of the Short-Term Effects of Different Bisphosphonates Using Intravital Two-Photon Microscopy.

JBMR Plus 2018 Nov 22;2(6):362-366. Epub 2018 Jun 22.

Department of Immunology and Cell Biology Graduate School of Medicine and Frontier Biosciences Osaka University 2-2 Yamada-oka Suita Osaka 565-0871 Japan.

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http://dx.doi.org/10.1002/jbm4.10057DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6237210PMC
November 2018

Histone methylation regulator PTIP is required to maintain normal and leukemic bone marrow niches.

Proc Natl Acad Sci U S A 2018 10 8;115(43):E10137-E10146. Epub 2018 Oct 8.

Department of Epigenetics and Molecular Carcinogenesis, University of Texas MD Anderson Cancer Center, Houston, TX 77030;

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http://www.pnas.org/lookup/doi/10.1073/pnas.1806019115
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http://dx.doi.org/10.1073/pnas.1806019115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6205459PMC
October 2018

The 17,18-epoxyeicosatetraenoic acid-G protein-coupled receptor 40 axis ameliorates contact hypersensitivity by inhibiting neutrophil mobility in mice and cynomolgus macaques.

J Allergy Clin Immunol 2018 08 27;142(2):470-484.e12. Epub 2017 Dec 27.

Laboratory of Vaccine Materials, Center for Vaccine and Adjuvant Research, and Laboratory of Gut Environmental System, National Institutes of Biomedical Innovation, Health and Nutrition (NIBIOHN), Ibaraki, Japan; Department of Microbiology and Immunology, Kobe University Graduate School of Medicine, Kobe, Japan; Division of Mucosal Immunology, Department of Microbiology and Immunology and International Research and Development Center for Mucosal Vaccines, Institute of Medical Science, University of Tokyo, Tokyo, Japan; Graduate School of Medicine, Graduate School of Pharmaceutical Sciences, Graduate School of Dentistry, Osaka University, Suita, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2017.09.053DOI Listing
August 2018

visualisation of different modes of action of biological DMARDs inhibiting osteoclastic bone resorption.

Ann Rheum Dis 2018 08 28;77(8):1219-1225. Epub 2018 Apr 28.

Department of Immunology and Cell Biology, Graduate School of Medicine and Frontier Biosciences, Osaka University, Osaka, Japan.

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http://dx.doi.org/10.1136/annrheumdis-2017-212880DOI Listing
August 2018

Claudin-3 Loss Causes Leakage of Sweat from the Sweat Gland to Contribute to the Pathogenesis of Atopic Dermatitis.

J Invest Dermatol 2018 06 23;138(6):1279-1287. Epub 2017 Dec 23.

Department of Dermatology, Course of Integrated Medicine, Graduate School of Medicine, Osaka University, Osaka, Japan.

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https://linkinghub.elsevier.com/retrieve/pii/S0022202X173335
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http://dx.doi.org/10.1016/j.jid.2017.11.040DOI Listing
June 2018

[Basis of intravital bone imaging.]

Clin Calcium 2018;28(2):175-179

Department of Immunology and Cell Biology, Graduate School of Medicine and Frontier Biosciences, Osaka University, Japan.

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http://dx.doi.org/CliCa1802175179DOI Listing
June 2018

[Intravital bone imaging:osteoclast.]

Clin Calcium 2018;28(2):211-216

Department of Immunology and Cell Biology, Graduate School of Medicine and Frontier Biosciences, Osaka University, Japan.

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http://dx.doi.org/CliCa1802211216DOI Listing
June 2018

[The effects of anti-bone-resorptive drugs analyzed by intravital bone imaging.]

Clin Calcium 2018;28(2):237-242

Department of Immunology and Cell Biology, Graduate School of Medicine and Frontier Biosciences, Osaka University, Japan.

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http://dx.doi.org/CliCa1802237242DOI Listing
June 2018

[Analysis of the bone anabolic agent by intravital imaging technique.]

Clin Calcium 2018;28(2):243-248

Department of Immunology and Cell Biology, Graduate School of Medicine and Frontier Biosciences, Osaka University, Japan.

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http://dx.doi.org/CliCa1802243248DOI Listing
June 2018

Chiral cell sliding drives left-right asymmetric organ twisting.

Elife 2018 06 12;7. Epub 2018 Jun 12.

Department of Physiology and Cell Biology, Graduate School of Medicine, Kobe University, Kobe, Japan.

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http://dx.doi.org/10.7554/eLife.32506DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5997448PMC
June 2018

In vivo live imaging of bone cells.

Histochem Cell Biol 2018 Apr 23;149(4):417-422. Epub 2018 Jan 23.

Department of Immunology and Cell Biology, Graduate School of Medicine and Frontier Biosciences, and WPI-Immunology Frontier Research Center, Osaka University, 2-2 Yamada-oka, Suita, Osaka, 565-0871, Japan.

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http://dx.doi.org/10.1007/s00418-018-1638-0DOI Listing
April 2018

In vivo imaging of T cell lymphoma infiltration process at the colon.

Sci Rep 2018 03 5;8(1):3978. Epub 2018 Mar 5.

Graduate School of Arts and Sciences, The University of Tokyo, 3-8-1 Komaba, Meguro-ku, Tokyo, 153-8902, Japan.

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http://dx.doi.org/10.1038/s41598-018-22399-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5838227PMC
March 2018

[Update on recent progress in vitamin D research. The effects of vitamin D in autoinflammatory diseases.]

Clin Calcium 2017;27(11):1551-1559

Department of Immunology and Cell Biology, Graduate School of Medicine, Osaka University, Japan.

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http://dx.doi.org/CliCa171115511559DOI Listing
February 2018

[Imaging of bone and joint destruction].

Nihon Rinsho Meneki Gakkai Kaishi 2017 ;40(5):344-351

Department of Immunology and Cell Biology, Graduate School of Medicine, Osaka University.

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http://dx.doi.org/10.2177/jsci.40.344DOI Listing
January 2018

Bone marrow cavity segmentation using graph-cuts with wavelet-based texture feature.

J Bioinform Comput Biol 2017 Oct 25;15(5):1740004. Epub 2017 Aug 25.

* Graduate School of Information Science and Technology, Osaka University, Yamadaoka 1-5, Suita, Osaka, Japan.

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http://www.worldscientific.com/doi/abs/10.1142/S021972001740
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http://dx.doi.org/10.1142/S0219720017400042DOI Listing
October 2017

Dynamic analysis of immune inflammation and bone destruction by intravital imaging.

Nihon Rinsho Meneki Gakkai Kaishi 2016 ;39(2):124-9

Department of Immunology and Cell Biology, Graduate School of Medicine and Frontier Biosciences, Osaka University.

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http://dx.doi.org/10.2177/jsci.39.124DOI Listing
March 2017

Roles for Cell-Cell Adhesion and Contact in Obesity-Induced Hepatic Myeloid Cell Accumulation and Glucose Intolerance.

Cell Rep 2017 03;18(11):2766-2779

Department of Molecular Endocrinology and Metabolism, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Bunkyo-ku, Tokyo 113-8510, Japan; Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Fukuoka 812-8582, Japan; Japan Agency for Medical Research and Development, CREST, Chiyoda-ku, Tokyo 100-0004, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2017.02.039DOI Listing
March 2017

Real-time intravital imaging of pH variation associated with osteoclast activity.

Nat Chem Biol 2016 08 6;12(8):579-85. Epub 2016 Jun 6.

Department of Material and Life Science, Graduate School of Engineering, Osaka University, Suita, Osaka, Japan.

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http://dx.doi.org/10.1038/nchembio.2096DOI Listing
August 2016

Prickle1 promotes focal adhesion disassembly in cooperation with the CLASP-LL5β complex in migrating cells.

J Cell Sci 2016 08 4;129(16):3115-29. Epub 2016 Jul 4.

Department of Molecular Biology and Biochemistry, Graduate School of Medicine, Osaka University, 2-2 Yamada-oka, Suita, Osaka 565-0871, Japan

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http://dx.doi.org/10.1242/jcs.185439DOI Listing
August 2016

Cell-cycle-controlled radiation therapy was effective for treating a murine malignant melanoma cell line in vitro and in vivo.

Sci Rep 2016 08 2;6:30689. Epub 2016 Aug 2.

Department of Immunology and Cell Biology, Graduate School of Medicine and Frontier Biosciences 2-2, Yamada-oka, Suita, Osaka, Japan.

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http://dx.doi.org/10.1038/srep30689DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4969753PMC
August 2016

Intravital imaging of the cellular dynamics of LysM-positive cells in a murine corneal suture model.

Br J Ophthalmol 2016 Mar 16;100(3):432-5. Epub 2015 Nov 16.

Department of Frontier Medical Science and Technology for Ophthalmology, Kyoto Prefectural University of Medicine, Kyoto, Japan.

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http://dx.doi.org/10.1136/bjophthalmol-2015-307024DOI Listing
March 2016

Visualization of Intravital Immune Cell Dynamics After Conjunctival Surgery Using Multiphoton Microscopy.

Invest Ophthalmol Vis Sci 2016 Mar;57(3):1207-12

Department of Ophthalmology Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan.

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http://dx.doi.org/10.1167/iovs.15-18507DOI Listing
March 2016

Adipose tissue macrophages induce PPARγ-high FOXP3(+) regulatory T cells.

Sci Rep 2015 Nov 19;5:16801. Epub 2015 Nov 19.

Department of Metabolic Medicine, Osaka University Graduate School of Medicine, 2-2, Yamamdaoka, Suita, Osaka, Japan.

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http://dx.doi.org/10.1038/srep16801DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4652162PMC
November 2015

Oxysterols and EBI2 promote osteoclast precursor migration to bone surfaces and regulate bone mass homeostasis.

J Exp Med 2015 Oct 5;212(11):1931-46. Epub 2015 Oct 5.

Department of Immunobiology and Department of Orthopaedics and Rehabilitation, Yale University School of Medicine, New Haven, CT 06510

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http://www.jem.org/lookup/doi/10.1084/jem.20150088
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http://dx.doi.org/10.1084/jem.20150088DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4612084PMC
October 2015

[Frontiers in Live Bone Imaging Researches. Intravital imaging of osteoclast dynamics].

Clin Calcium 2015 Jun;25(6):815-22

Department of Immunology and Cell Biology, Graduate School of Medicine and Frontier Biosciences, Osaka University, Japan./Japan Science and Technology Agency, CREST, Japan.

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http://dx.doi.org/CliCa1506815822DOI Listing
June 2015

[Intravital multiphoton imaging of live bone tissues revealing hematopoietic cell dynamics in vivo].

Rinsho Ketsueki 2015 Jun;56(6):594-600

Department of Immunology and Cell Biology, Graduate School of Medicine and Frontier Biosciences, Osaka University.

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http://dx.doi.org/10.11406/rinketsu.56.594DOI Listing
June 2015

Intravital bone imaging by two-photon excitation microscopy to identify osteocytic osteolysis in vivo.

Bone 2015 May 24;74:134-9. Epub 2015 Jan 24.

Department of Immunology and Cell Biology, Graduate School of Medicine and Frontier Biosciences, Osaka University, Osaka, Japan; WPI-Immunology Frontier Research Center, Osaka University, Osaka, Japan; JST, CREST, Tokyo, Japan. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S87563282150002
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http://dx.doi.org/10.1016/j.bone.2015.01.013DOI Listing
May 2015

Visualized macrophage dynamics and significance of S100A8 in obese fat.

Proc Natl Acad Sci U S A 2015 Apr 6;112(16):E2058-66. Epub 2015 Apr 6.

Department of Metabolic Medicine, Graduate School of Medicine, Osaka University, Osaka 565-0871, Japan;

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http://dx.doi.org/10.1073/pnas.1409480112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4413348PMC
April 2015

RFPL4A increases the G1 population and decreases sensitivity to chemotherapy in human colorectal cancer cells.

J Biol Chem 2015 Mar 20;290(10):6326-37. Epub 2015 Jan 20.

From the Departments of Immunology and Cell Biology, the WPI-Immunology Frontier Research Center, Osaka University, 3-1 Yamada-oka, Suita, Osaka 565-0871, Japan, the Japan Science and Technology Agency (JST), CREST, 5 Sanban-cho, Chiyoda-ku, Tokyo 102-0075, Japan

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http://dx.doi.org/10.1074/jbc.M114.614859DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4358269PMC
March 2015

[Current Topics on Vitamin D. The effects of vitamin D on the immune system].

Clin Calcium 2015 Mar;25(3):359-65

Department of Immunology and Cell Biology, Graduate School of Medicine, Osaka University, Japan./Japan Science and Technology Agency, CREST.

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http://dx.doi.org/CliCa1503359365DOI Listing
March 2015

Sweat, the driving force behind normal skin: an emerging perspective on functional biology and regulatory mechanisms.

J Dermatol Sci 2015 Jan 6;77(1):3-10. Epub 2014 Sep 6.

Department of Dermatology, Course of Integrated Medicine, Graduate School of Medicine, Osaka University, 2-2 Yamadaoka, Suita, Osaka, Japan.

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https://linkinghub.elsevier.com/retrieve/pii/S09231811140021
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http://dx.doi.org/10.1016/j.jdermsci.2014.08.011DOI Listing
January 2015

Intravital multiphoton microscopy for dissecting cellular dynamics in arthritic inflammation and bone destruction.

Methods Mol Biol 2014 ;1142:1-10

Department of Immunology and Cell Biology, Graduate School of Medicine and Frontier Biosciences, Osaka University, Suita, Osaka, Japan.

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http://link.springer.com/10.1007/978-1-4939-0404-4_1
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http://dx.doi.org/10.1007/978-1-4939-0404-4_1DOI Listing
November 2014

Cell cycle-dependent Rho GTPase activity dynamically regulates cancer cell motility and invasion in vivo.

PLoS One 2013 30;8(12):e83629. Epub 2013 Dec 30.

Department of Immunology and Cell Biology, Graduate School of Medicine, Osaka University, Suita, Osaka, Japan ; Laboratory of Cellular Dynamics, WPI-Immunology Frontier Research Center, Osaka University, Suita, Osaka, Japan ; JST, CREST, Chiyoda-ku, Tokyo, Japan.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0083629PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3875446PMC
September 2014

Left-right asymmetry is formed in individual cells by intrinsic cell chirality.

Mech Dev 2014 Aug 4;133:146-62. Epub 2014 May 4.

Department of Biological Sciences, Osaka University, Toyonaka, Osaka 560-0043, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.mod.2014.04.002DOI Listing
August 2014

[Bone metabolism and cardiovascular function update. Relationship between immune and vascular system in bone tissues].

Clin Calcium 2014 Jul;24(7):63-8

Department of Immunology and Cell Biology, Graduate School of Medicine, Osaka University, Japan./Japan Science and Technology Agency, CREST.

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http://dx.doi.org/CliCa140710311036DOI Listing
July 2014

Filamin acts as a key regulator in epithelial defence against transformed cells.

Nat Commun 2014 Jul 31;5:4428. Epub 2014 Jul 31.

1] Division of Molecular Oncology, Institute for Genetic Medicine, Hokkaido University Graduate School of Chemical Sciences and Engineering, Kita 15, Nishi 7, Kita-ku, Sapporo, Hokkaido 060-0815, Japan [2] MRC Laboratory for Molecular Cell Biology and Cell Biology Unit, University College London, London WC1E 6BT, UK [3] Department of Cell and Developmental Biology, University College London, London WC1E 6BT, UK.

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http://dx.doi.org/10.1038/ncomms5428DOI Listing
July 2014

Olopatadine hydrochloride restores histamine-induced impaired sweating.

J Dermatol Sci 2014 Jun 28;74(3):260-1. Epub 2014 Feb 28.

Department of Dermatology, Graduate School of Medicine, Osaka University, Osaka, Japan.

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http://dx.doi.org/10.1016/j.jdermsci.2014.02.004DOI Listing
June 2014

[Bone and Stem Cells. Intravital imaging of bone marrow microenvironment].

Clin Calcium 2014 Apr;24(4):541-6

Department of Immunology and Cell Biology, Graduate School of Medicine and Frontier Biosciences, Osaka University, Japan./Japan Science and Technology Agency, CREST, Japan.

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http://dx.doi.org/CliCa1404541546DOI Listing
April 2014

Generation of colonic IgA-secreting cells in the caecal patch.

Nat Commun 2014 Apr 10;5:3704. Epub 2014 Apr 10.

1] Laboratory of Immune Regulation, Department of Microbiology and Immunology, Graduate School of Medicine, WPI Immunology Frontier Research Center, Osaka University, Suita, Osaka 565-0871, Japan [2] Core Research for Evolutional Science and Technology, Japan Science and Technology Agency, Saitama 332-0012, Japan.

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http://dx.doi.org/10.1038/ncomms4704DOI Listing
April 2014

Dynamic analysis of histamine-mediated attenuation of acetylcholine-induced sweating via GSK3β activation.

J Invest Dermatol 2014 Feb 30;134(2):326-334. Epub 2013 Jul 30.

Department of Dermatology, Course of Integrated Medicine, Graduate School of Medicine, Osaka University, Osaka, Japan.

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http://dx.doi.org/10.1038/jid.2013.323DOI Listing
February 2014

[Dynamics of bone resorption analyzed by intravital imaging].

Clin Calcium 2013 Nov;23(11):1627-33

Department of Immunology and Cell Biology, Graduate School of Medicine and Frontier Biosciences, Osaka University, Japan./Japan Science and Technology Agency, CREST, Japan.

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http://dx.doi.org/CliCa131116271633DOI Listing
November 2013

Dynamic live imaging of bone: opening a new era with 'bone histodynametry'.

J Bone Miner Metab 2013 Sep 2;31(5):507-11. Epub 2013 Apr 2.

Laboratory of Cellular Dynamics, Immunology Frontier Research Center, Osaka University, Suita, Japan,

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http://dx.doi.org/10.1007/s00774-013-0437-xDOI Listing
September 2013

Layer V cortical neurons require microglial support for survival during postnatal development.

Nat Neurosci 2013 May 24;16(5):543-51. Epub 2013 Mar 24.

Department of Molecular Neuroscience, Graduate School of Medicine, Osaka University, Osaka, Japan.

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http://dx.doi.org/10.1038/nn.3358DOI Listing
May 2013

Sphingosine-1-phosphate-mediated osteoclast precursor monocyte migration is a critical point of control in antibone-resorptive action of active vitamin D.

Proc Natl Acad Sci U S A 2013 Apr 8;110(17):7009-13. Epub 2013 Apr 8.

Laboratory of Cellular Dynamics, Immunology Frontier Research Center, Osaka University, Osaka 565-0871, Japan.

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http://dx.doi.org/10.1073/pnas.1218799110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3637769PMC
April 2013

[Analysis of bone tissues by using fluorescent imaging].

Clin Calcium 2013 Mar;23(3):355-60

Osaka University, Japan Science and Technology, CREST, Japan.

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http://dx.doi.org/CliCa1303355360DOI Listing
March 2013

Osteoclast migration, differentiation and function: novel therapeutic targets for rheumatic diseases.

Rheumatology (Oxford) 2013 Feb 28;52(2):226-34. Epub 2012 Sep 28.

Laboratory of Cellular Dynamics, Immunology Frontier Research Center, Osaka University, 3-1 Yamada-oka, Suita, Osaka, Japan.

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http://dx.doi.org/10.1093/rheumatology/kes259DOI Listing
February 2013

Dynamic visualization of RANKL and Th17-mediated osteoclast function.

J Clin Invest 2013 Feb 16;123(2):866-73. Epub 2013 Jan 16.

Laboratory of Cellular Dynamics, WPI–Immunology Frontier Research Center, Osaka University, Osaka, Japan.

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http://dx.doi.org/10.1172/JCI65054DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3561830PMC
February 2013

Sphingosine-1-phosphate signaling controlling osteoclasts and bone homeostasis.

Biochim Biophys Acta 2013 Jan 9;1831(1):223-7. Epub 2012 Jun 9.

Osaka University, Osaka, Japan.

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http://dx.doi.org/10.1016/j.bbalip.2012.06.002DOI Listing
January 2013

Recent advances in intravital imaging of dynamic biological systems.

J Pharmacol Sci 2012 13;119(3):193-7. Epub 2012 Jun 13.

Laboratory of Cellular Dynamics, WPI-Immunology Frontier Research Center, Osaka University, 3-1 Yamada-oka, Suita, Osaka 565-0871, Japan.

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http://dx.doi.org/10.1254/jphs.12r03cpDOI Listing
January 2013

Systemic circulation and bone recruitment of osteoclast precursors tracked by using fluorescent imaging techniques.

J Immunol 2013 Jan 14;190(2):605-12. Epub 2012 Dec 14.

Laboratory of Cellular Dynamics, World Premier International Research Center Initiative-Immunology Frontier Research Center, Osaka University, Suita, Osaka 565-0871, Japan.

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http://www.jimmunol.org/cgi/doi/10.4049/jimmunol.1201345
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http://dx.doi.org/10.4049/jimmunol.1201345DOI Listing
January 2013

Use of intravital microscopy and in vitro chemotaxis assays to study the roles of sphingosine-1-phosphate in bone homeostasis.

Methods Mol Biol 2012 ;874:129-39

Laboratory of Cellular Dynamics, WPI-Immunology Frontier Research Center, Osaka University, Suita, Japan.

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http://dx.doi.org/10.1007/978-1-61779-800-9_10DOI Listing
November 2012

[Bone and calcium update; bone research update. Trafficking of osteoclast precursors visualized by intravital imaging technology].

Clin Calcium 2011 Dec;21(12):85-91

Laboratory of Cellular Dynamics, Immunology Frontier Research Center, Osaka University, JST, CREST, Japan.

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http://dx.doi.org/CliCa111218351841DOI Listing
December 2011

In vivo fluorescence imaging of bone-resorbing osteoclasts.

J Am Chem Soc 2011 Nov 13;133(44):17772-6. Epub 2011 Oct 13.

Laboratory of Chemical Imaging Techniques, Immunology Frontier Research Center (IFReC), Osaka University, Osaka, Japan.

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http://dx.doi.org/10.1021/ja2064582DOI Listing
November 2011

[In vivo imaging of mature osteoclasts and RANKL signaling].

Clin Calcium 2011 Aug;21(8):1181-5

Laboratory of Cellular Dynamics, Osaka University, Japan.

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http://dx.doi.org/CliCa110811811185DOI Listing
August 2011

S1P-targeted therapy for elderly rheumatoid arthritis patients with osteoporosis.

Rheumatol Int 2011 Jul 28;31(7):967-9. Epub 2010 Nov 28.

Department of Rheumatology and Clinical Research, National Osaka-Minami Medical Center, Osaka, Japan.

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http://link.springer.com/content/pdf/10.1007/s00296-010-1634
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http://link.springer.com/10.1007/s00296-010-1634-8
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http://dx.doi.org/10.1007/s00296-010-1634-8DOI Listing
July 2011

The role of sphingosine 1-phosphate in migration of osteoclast precursors; an application of intravital two-photon microscopy.

Mol Cells 2011 May 25;31(5):399-403. Epub 2011 Feb 25.

Laboratory of Biological Imaging, WPI-Immunology Frontier Research Center, Osaka University, Osaka, Japan.

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http://dx.doi.org/10.1007/s10059-011-1010-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3887611PMC
May 2011

[Encounter of cancer cells with bone. In vivo imaging of osteoclasts and their precursors in intact bone tissues].

Clin Calcium 2011 Mar;21(3):372-8

Laboratory of Biological Imaging, Immunology Frontier Research Center, Osaka University.

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http://dx.doi.org/CliCa1103372378DOI Listing
March 2011

Chemorepulsion by blood S1P regulates osteoclast precursor mobilization and bone remodeling in vivo.

J Exp Med 2010 Dec 6;207(13):2793-8. Epub 2010 Dec 6.

Laboratory of Biological Imaging, WPI-Immunology Frontier Research Center, Osaka University, Osaka 565-0871, Japan.

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http://dx.doi.org/10.1084/jem.20101474DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3005230PMC
December 2010