Publications by authors named "Jung Hwa Oh"

62Publications

Toxicity of orally administered food-grade titanium dioxide nanoparticles.

J Appl Toxicol 2020 Nov 25. Epub 2020 Nov 25.

East-West Medical Science Research Institute, Kyung Hee University, Seoul, Republic of Korea.

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http://dx.doi.org/10.1002/jat.4099DOI Listing
November 2020

An adverse outcome pathway for immune-mediated and allergic hepatitis: a case study with the NSAID diclofenac.

Arch Toxicol 2020 08 5;94(8):2733-2748. Epub 2020 May 5.

Centre for Pharmacology and Toxicology, Hannover Medical School, 30625, Hannover, Germany.

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http://dx.doi.org/10.1007/s00204-020-02767-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7395045PMC
August 2020

Increased hepatic acylcarnitines after oral administration of amiodarone in rats.

J Appl Toxicol 2020 Jul 21;40(7):1004-1013. Epub 2020 Feb 21.

Department of Pharmacology and PharmacoGenomics Research Center, Inje University College of Medicine, Busan, South Korea.

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http://dx.doi.org/10.1002/jat.3960DOI Listing
July 2020

Amorphous silica nanoparticle-induced pulmonary inflammatory response depends on particle size and is sex-specific in rats.

Toxicol Appl Pharmacol 2020 03 20;390:114890. Epub 2020 Jan 20.

Graduate School of East-West Medical Science, Kyung Hee University, Yongin 17104, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.taap.2020.114890DOI Listing
March 2020

Blockade of STAT3 Causes Severe In Vitro and In Vivo Maturation Defects in Intestinal Organoids Derived from Human Embryonic Stem Cells.

J Clin Med 2019 Jul 4;8(7). Epub 2019 Jul 4.

Stem Cell Convergence Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon 34141, Korea.

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http://dx.doi.org/10.3390/jcm8070976DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678857PMC
July 2019

Comparative omics analyses of hepatotoxicity induced by oral azole drugs in mice liver and primary hepatocytes.

Toxicol Mech Methods 2019 Sep 11;29(7):531-541. Epub 2019 Jun 11.

a Department of Predictive Toxicology , Korea Institute of Toxicology (KIT) , Daejeon , Republic of Korea.

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http://dx.doi.org/10.1080/15376516.2019.1619214DOI Listing
September 2019

Human three-dimensional in vitro model of hepatic zonation to predict zonal hepatotoxicity.

J Biol Eng 2019 6;13:22. Epub 2019 Mar 6.

2Department of Predictive Toxicology, Korea Institute of Toxicology (KIT), Daejeon, 34114 Republic of Korea.

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http://dx.doi.org/10.1186/s13036-019-0148-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6404355PMC
March 2019

Gene networking in colistin-induced nephrotoxicity reveals an adverse outcome pathway triggered by proteotoxic stress.

Int J Mol Med 2019 Mar 8;43(3):1343-1355. Epub 2019 Jan 8.

Department of Predictive Toxicology, Korea Institute of Toxicology, Daejeon 34114, Republic of Korea.

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http://dx.doi.org/10.3892/ijmm.2019.4052DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365082PMC
March 2019

SETDB1 regulates SMAD7 expression for breast cancer metastasis.

BMB Rep 2019 Feb;52(2):139-144

Korea Research Institute of Bioscience and Biotechnology, and Department of Functional Genomics, Korea University of Science and Technology, Daejeon 34141, Korea.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6443319PMC
February 2019

Novel prognostic marker PRMT1 regulates cell growth via downregulation of CDKN1A in HCC.

Oncotarget 2017 Dec 14;8(70):115444-115455. Epub 2017 Dec 14.

Korea Research Institute of Bioscience and Biotechnology, Daejeon, Republic of Korea.

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http://dx.doi.org/10.18632/oncotarget.23296DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5777784PMC
December 2017

The pathogenesis of diclofenac induced immunoallergic hepatitis in a canine model of liver injury.

Oncotarget 2017 Dec 23;8(64):107763-107824. Epub 2017 Sep 23.

Centre for Pharmacology and Toxicology, Hannover Medical School, 30625 Hannover, Germany.

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http://dx.doi.org/10.18632/oncotarget.21201DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5746105PMC
December 2017

Comparative analysis of human embryonic stem cell‑derived neural stem cells as an in vitro human model.

Int J Mol Med 2018 Feb 30;41(2):783-790. Epub 2017 Nov 30.

Stem Cell Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon 34141, Republic of Korea.

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http://dx.doi.org/10.3892/ijmm.2017.3298DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5752237PMC
February 2018

and imaging and tracking of intestinal organoids from human induced pluripotent stem cells.

FASEB J 2018 01 29;32(1):111-122. Epub 2017 Aug 29.

Stem Cell Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon, South Korea,

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http://www.fasebj.org/doi/10.1096/fj.201700504R
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http://dx.doi.org/10.1096/fj.201700504RDOI Listing
January 2018

Somatic Mutations in TSC1 and TSC2 Cause Focal Cortical Dysplasia.

Am J Hum Genet 2017 Mar 16;100(3):454-472. Epub 2017 Feb 16.

Brain Korea 21 Plus Project, Graduate School of Medical Science and Engineering, Korea Advanced Institute of Science & Technology, Daejeon 34141, South Korea. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2017.01.030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5339289PMC
March 2017

Analysis of genomic responses in a rat lung model treated with a humidifier sterilizer containing polyhexamethyleneguanidine phosphate.

Toxicol Lett 2017 Feb 15;268:36-43. Epub 2016 Dec 15.

Department of Inhalation Toxicology Research, Korea Institute of Toxicology, Jeonbuk 56212, Republic of Korea; Department of Human and Environmental Toxicology, University of Science & Technology, Daejeon, 34113, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.toxlet.2016.11.005DOI Listing
February 2017

Characterization of urinary metabolites as biomarkers of colistin-induced nephrotoxicity in rats by a liquid chromatography/mass spectrometry-based metabolomics approach.

Toxicol Lett 2016 Apr 3;248:52-60. Epub 2016 Mar 3.

Department of Pharmacology and Pharmacogenomics Research center, Inje University, College of Medicine, Bokjiro 75, Busanjin-Gu, Busan 614-735 South Korea. Electronic address:

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http://dx.doi.org/10.1016/j.toxlet.2016.02.018DOI Listing
April 2016

Immunogenomics reveal molecular circuits of diclofenac induced liver injury in mice.

Oncotarget 2016 Mar;7(12):14983-5017

Centre for Pharmacology and Toxicology, Hannover Medical School, 30625 Hannover, Germany.

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http://dx.doi.org/10.18632/oncotarget.7698DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4924767PMC
March 2016

Integrative analysis of genes and miRNA alterations in human embryonic stem cells-derived neural cells after exposure to silver nanoparticles.

Toxicol Appl Pharmacol 2016 May 6;299:8-23. Epub 2015 Nov 6.

Korea Institute of Toxicology (KIT), Daejeon 34114, Republic of Korea; Department of human and environmental toxicology, University of Science & Technology, Daejeon 34113, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.taap.2015.11.004DOI Listing
May 2016

Increased serum bile acid concentration following low-dose chronic administration of thioacetamide in rats, as evidenced by metabolomic analysis.

Toxicol Appl Pharmacol 2015 Oct 26;288(2):213-22. Epub 2015 Jul 26.

Department of Pharmacology and Pharmacogenomics Research Center, Inje University, College of Medicine, Bokjiro 75, Busanjin-Gu, Busan 614-735, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.taap.2015.07.016DOI Listing
October 2015

Genomic and proteomic analyses of 1,3-dinitrobenzene-induced testicular toxicity in Sprague-Dawley rats.

Reprod Toxicol 2014 Jan 16;43:45-55. Epub 2013 Oct 16.

Korea Institute of Toxicology, Daejeon 305-343, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.reprotox.2013.10.004DOI Listing
January 2014

Nonylphenol-induced apoptotic cell death in mouse TM4 Sertoli cells via the generation of reactive oxygen species and activation of the ERK signaling pathway.

J Appl Toxicol 2014 Jun 16;34(6):628-36. Epub 2013 May 16.

Division of Toxicological Research, Korea Institute of Toxicology, Daejeon, 305-343, Korea.

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http://dx.doi.org/10.1002/jat.2886DOI Listing
June 2014

Gene expression analysis of toxicological pathways in TM3 leydig cell lines treated with Ethane dimethanesulfonate.

J Biochem Mol Toxicol 2012 Jun;26(6):213-23

Division of Research and Development, Korea Institute of Toxicology, Daejeon, 305-343, Republic of Korea.

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http://dx.doi.org/10.1002/jbt.21409DOI Listing
June 2012

miRNA regulation of cytotoxic effects in mouse Sertoli cells exposed to nonylphenol.

Reprod Biol Endocrinol 2011 Sep 14;9:126. Epub 2011 Sep 14.

Division of Research and Development, Korea Institute of Toxicology, 19 Shinsung-ro, Yuseong, Daejeon, 305-343, Korea.

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http://dx.doi.org/10.1186/1477-7827-9-126DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3196907PMC
September 2011

Inflammatory response in rat lungs with recurrent exposure to welding fumes: a transcriptomic approach.

Toxicol Ind Health 2012 Apr 5;28(3):203-15. Epub 2011 Jul 5.

Division of Research and Development, Korea Institute of Toxicology, Daejeon, Republic of Korea.

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http://dx.doi.org/10.1177/0748233711410906DOI Listing
April 2012

Silver nanoparticles induce apoptosis and G2/M arrest via PKCζ-dependent signaling in A549 lung cells.

Arch Toxicol 2011 Dec 25;85(12):1529-40. Epub 2011 May 25.

Department of Anatomy, Chungnam National University, Daejeon 301-040, Republic of Korea.

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http://dx.doi.org/10.1007/s00204-011-0714-1DOI Listing
December 2011

Identification of biomarkers of chemically induced hepatocarcinogenesis in rasH2 mice by toxicogenomic analysis.

Arch Toxicol 2011 Dec 24;85(12):1627-40. Epub 2011 May 24.

Division of Research and Development, Korea Institute of Toxicology, 19 Shinsung-ro, Yuseong-gu, Daejeon 305-343, Korea.

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http://dx.doi.org/10.1007/s00204-011-0715-0DOI Listing
December 2011

Cafestol, a coffee-specific diterpene, induces apoptosis in renal carcinoma Caki cells through down-regulation of anti-apoptotic proteins and Akt phosphorylation.

Chem Biol Interact 2011 Apr 18;190(2-3):102-8. Epub 2011 Feb 18.

Department of Immunology, School of Medicine, Keimyung University, 2800 Dalgubeoldaero, Dalseo-Gu, Daegu 704-701, Republic of Korea.

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http://dx.doi.org/10.1016/j.cbi.2011.02.013DOI Listing
April 2011

The coffee diterpene kahweol sensitizes TRAIL-induced apoptosis in renal carcinoma Caki cells through down-regulation of Bcl-2 and c-FLIP.

Chem Biol Interact 2010 Jun 18;186(1):36-42. Epub 2010 Apr 18.

Department of Immunology, School of Medicine, Keimyung University, 2800 Dalgubeoldaero, Dalseo-Gu, Daegu, South Korea.

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http://dx.doi.org/10.1016/j.cbi.2010.04.013DOI Listing
June 2010

Simultaneous gene expression signature of heart and peripheral blood mononuclear cells in astemizole-treated rats.

Arch Toxicol 2010 Aug 11;84(8):609-18. Epub 2010 Mar 11.

Korea Institute of Toxicology, 19 Shinseong-ro, Yuseong-gu, Daejeon 305-343, Republic of Korea.

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http://dx.doi.org/10.1007/s00204-010-0529-5DOI Listing
August 2010

A novel cyclin-dependent kinase inhibitor down-regulates tumor necrosis factor-alpha (TNF-alpha)-induced expression of cell adhesion molecules by inhibition of NF-kappaB activation in human pulmonary epithelial cells.

Int Immunopharmacol 2010 May 13;10(5):572-9. Epub 2010 Feb 13.

Department of Immunology, School of Medicine, Keimyung University, 2800 Dalgubeoldaero, Dalseo-Gu, Daegu, 704-701, South Korea.

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http://dx.doi.org/10.1016/j.intimp.2010.02.004DOI Listing
May 2010

PDbase: a database of Parkinson's disease-related genes and genetic variation using substantia nigra ESTs.

BMC Genomics 2009 Dec 3;10 Suppl 3:S32. Epub 2009 Dec 3.

Korean Bioinformation Center (KOBIC), Korea Research Institute of Bioscience and Biotechnology (KRIBB), 111 Gwahangno, Yuseong-gu, Daejeon 305-806, Korea.

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http://dx.doi.org/10.1186/1471-2164-10-S3-S32DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2788386PMC
December 2009

Full-length enriched cDNA library construction from tissues related to energy metabolism in pigs.

Mol Cells 2009 Dec 19;28(6):529-36. Epub 2009 Nov 19.

Division of Animal Genomics and Bioinformatics, National Institute of Animal Science, Rural Development Administration, Suwon 441-707, Korea.

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http://link.springer.com/10.1007/s10059-009-0147-3
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http://dx.doi.org/10.1007/s10059-009-0147-3DOI Listing
December 2009

Gene expression profiling in the lung tissue of cynomolgus monkeys in response to repeated exposure to welding fumes.

Arch Toxicol 2010 Mar;84(3):191-203

Division of Inhalation Toxicology, KIT Jeongeup Campus, 1051, Shinjeong-dong, Jeongeup, Jeollabuk-do, Korea.

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http://dx.doi.org/10.1007/s00204-009-0486-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2820669PMC
March 2010

The stoichiometric relationship between KCNH-2 and KCNE-2 in I(Kr) channel formation.

Int J Cardiol 2010 Nov 13;145(2):272-274. Epub 2009 Nov 13.

Korea Institute of Toxicology, 100 Jangdong, Yuseong, Daejeon, 305-343, Republic of Korea; Pharmacology and Toxicology, School of Engineering, University of Science and Technology, 113 Gwahangno, Yuseong, Daejeon, 305-333, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.ijcard.2009.09.552DOI Listing
November 2010

Generation of expression clone set for functional proteomics of human gastric and liver cancers.

Exp Biol Med (Maywood) 2009 Oct 13;234(10):1220-9. Epub 2009 Jul 13.

Laboratory of Human Genomics, Genome Research Center, KRIBB, Daejeon 305-806, Korea.

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http://dx.doi.org/10.3181/0812-RM-371DOI Listing
October 2009

Analysis of Gene Expression in 4,4'-Methylenedianiline-induced Acute Hepatotoxicity.

Toxicol Res 2009 Jun 1;25(2):85-92. Epub 2009 Jun 1.

14Toxicogenomics Team, Korea Institute of Toxicology, 19 Shinsung-ro, Yuseoung, Daejeon, 305-343 Korea.

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http://dx.doi.org/10.5487/TR.2009.25.2.085DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7006339PMC
June 2009

1,3-Dinitrobenzene induces apoptosis in TM4 mouse Sertoli cells: Involvement of the c-Jun N-terminal kinase (JNK) MAPK pathway.

Toxicol Lett 2009 Sep 27;189(2):145-51. Epub 2009 May 27.

Toxicogenomics Team, Korea Institute of Toxicology, Daejeon 305-343, Republic of Korea.

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http://dx.doi.org/10.1016/j.toxlet.2009.05.014DOI Listing
September 2009

Withaferin A inhibits tumor necrosis factor-alpha-induced expression of cell adhesion molecules by inactivation of Akt and NF-kappaB in human pulmonary epithelial cells.

Int Immunopharmacol 2009 May 21;9(5):614-9. Epub 2009 Feb 21.

Department of Immunology, School of Medicine, Keimyung University, Jung-Gu, Taegu, South Korea.

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http://dx.doi.org/10.1016/j.intimp.2009.02.002DOI Listing
May 2009

Microarray-based analysis of the lung recovery process after stainless-steel welding fume exposure in Sprague-Dawley rats.

Inhal Toxicol 2009 Feb;21(4):347-73

Division of Research and Development, Korea Institute of Toxicology, Yuseong, Daejeon, Republic of Korea.

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http://dx.doi.org/10.1080/08958370802464281DOI Listing
February 2009

Induction of apoptosis by withaferin A in human leukemia U937 cells through down-regulation of Akt phosphorylation.

Apoptosis 2008 Dec;13(12):1494-504

Department of Immunology, School of Medicine, Keimyung University, 194 DongSan-Dong Jung-Gu, Taegu 700-712, South Korea.

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http://link.springer.com/10.1007/s10495-008-0273-y
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http://dx.doi.org/10.1007/s10495-008-0273-yDOI Listing
December 2008

Withaferin A inhibits iNOS expression and nitric oxide production by Akt inactivation and down-regulating LPS-induced activity of NF-kappaB in RAW 264.7 cells.

Eur J Pharmacol 2008 Dec 24;599(1-3):11-7. Epub 2008 Sep 24.

Department of Immunology, School of Medicine, Keimyung University, 194 DongSan Dong Jung-Gu, Taegu, 700-712, South Korea.

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http://dx.doi.org/10.1016/j.ejphar.2008.09.017DOI Listing
December 2008

Time Dependent Gene Expression Changes in the Liver of Mice Treated with Benzene.

Biomark Insights 2008 Mar 28;3:191-201. Epub 2008 Mar 28.

Korea Institute of Toxicology, 100-Jang-Dong, Yuseong-Gu, Daejeon-305-600, Korea.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2688356PMC
http://dx.doi.org/10.4137/bmi.s590DOI Listing
March 2008

Identification of genes related to Parkinson's disease using expressed sequence tags.

DNA Res 2006 Dec 8;13(6):275-86. Epub 2007 Jan 8.

Laboratory of Human Genomics, Genome Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB) Daejeon, Korea.

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http://dx.doi.org/10.1093/dnares/dsl016DOI Listing
December 2006

Gene expression profiling of human HBV- and/or HCV-associated hepatocellular carcinoma cells using expressed sequence tags.

Int J Oncol 2006 Aug;29(2):315-27

Laboratory of Human Genomics, Genome Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon 305-333, Korea.

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August 2006

Identification of intrahepatic cholangiocarcinoma related genes by comparison with normal liver tissues using expressed sequence tags.

Biochem Biophys Res Commun 2006 Jul 11;345(3):1022-32. Epub 2006 May 11.

Laboratory of Human Genomics, Genome Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon, Republic of Korea.

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http://dx.doi.org/10.1016/j.bbrc.2006.04.175DOI Listing
July 2006

Gene expression profiling between embryonic and larval stages of the silkworm, Bombyx mori.

Biochem Biophys Res Commun 2006 May 15;343(3):864-72. Epub 2006 Mar 15.

Laboratory of Human Genomics, Genome Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejon 305-333, Republic of Korea.

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http://dx.doi.org/10.1016/j.bbrc.2006.03.023DOI Listing
May 2006

Transcriptome analysis of human gastric cancer.

Mamm Genome 2005 Dec 8;16(12):942-54. Epub 2005 Dec 8.

Laboratory of Human Genomics, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon , 305-333, Korea.

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http://dx.doi.org/10.1007/s00335-005-0075-2DOI Listing
December 2005

Identification of gastric cancer-related genes using a cDNA microarray containing novel expressed sequence tags expressed in gastric cancer cells.

Clin Cancer Res 2005 Jan;11(2 Pt 1):473-82

Laboratory of Human Genomics, Genome Research Center, Korea Research Institute of Bioscience and Biotechnology, Yusong, Daejeon, Korea.

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January 2005

Gene cataloging and expression profiling in human gastric cancer cells by expressed sequence tags.

Genomics 2004 Jun;83(6):1024-45

Laboratory of Human Genomics, Korea Research Institute of Bioscience and Biotechnology, Daejeon 305-333, South Korea.

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http://dx.doi.org/10.1016/j.ygeno.2003.12.002DOI Listing
June 2004

Construction of multi-purpose vectors, pCNS and pCNS-D2, are suitable for collection and functional study of large-scale cDNAs.

Plasmid 2004 May;51(3):217-26

Laboratory of Human Genomics, Division of Genomics and Proteomics, Korea Research Institute of Bioscience and Biotechnology, Daejeon 305-333, Republic of Korea.

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http://dx.doi.org/10.1016/j.plasmid.2004.01.001DOI Listing
May 2004

An improved method for constructing a full-length enriched cDNA library using small amounts of total RNA as a starting material.

Exp Mol Med 2003 Dec;35(6):586-90

Laboratory of Human Genomics, Division of Genomics and Proteomics, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon 305-333, Korea.

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http://dx.doi.org/10.1038/emm.2003.77DOI Listing
December 2003