Publications by authors named "Junaid Gamieldien"

32Publications

Identification of novel prognostic markers of survival time in high-risk neuroblastoma using gene expression profiles.

Oncotarget 2020 Nov 17;11(46):4293-4305. Epub 2020 Nov 17.

SAMRC Bioinformatics Unit, South African National Bioinformatics Institute, University of the Western Cape, Bellville, South Africa.

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http://dx.doi.org/10.18632/oncotarget.27808DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7679032PMC
November 2020

Exploring new genetic variants within COL5A1 intron 4-exon 5 region and TGF-β family with risk of anterior cruciate ligament ruptures.

J Orthop Res 2020 08 13;38(8):1856-1865. Epub 2020 Jan 13.

Division of Exercise Science and Sports Medicine (ESSM), University of Cape Town, Cape Town, South Africa.

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http://dx.doi.org/10.1002/jor.24585DOI Listing
August 2020

FTO haplotyping underlines high obesity risk for European populations.

BMC Med Genomics 2019 03 13;12(Suppl 2):46. Epub 2019 Mar 13.

Federal Research Center Institute of Cytology and Genetics SB RAS, 10 Lavrentieva Ave, Novosibirsk, Russian Federation, 630090.

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http://dx.doi.org/10.1186/s12920-019-0491-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6417164PMC
March 2019

Defining the molecular signatures of Achilles tendinopathy and anterior cruciate ligament ruptures: A whole-exome sequencing approach.

PLoS One 2018 25;13(10):e0205860. Epub 2018 Oct 25.

Division of Exercise Science and Sports Medicine, Department of Human Biology, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0205860PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6201890PMC
April 2019

Exome sequencing identifies novel dysferlin mutation in a family with pauci-symptomatic heterozygous carriers.

BMC Med Genet 2018 06 7;19(1):95. Epub 2018 Jun 7.

South African National Bioinformatics Institute, University of the Western Cape, Private Bag X17, Bellville, 7535, South Africa.

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http://dx.doi.org/10.1186/s12881-018-0613-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992709PMC
June 2018

A 35-gene signature discriminates between rapidly- and slowly-progressing glioblastoma multiforme and predicts survival in known subtypes of the cancer.

BMC Cancer 2018 04 3;18(1):377. Epub 2018 Apr 3.

South African Bioinformatics Institute and SAMRC Unit for Bioinformatics Capacity Development, University of the Western Cape, Bellville, 7535, Western Cape, 7530, South Africa.

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http://dx.doi.org/10.1186/s12885-018-4103-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5883543PMC
April 2018

Exome sequencing identifies targets in the treatment-resistant ophthalmoplegic subphenotype of myasthenia gravis.

Neuromuscul Disord 2017 Sep 21;27(9):816-825. Epub 2017 Jun 21.

Neurology Division, Department of Medicine, University of Cape Town, Cape Town, South Africa. Electronic address:

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http://dx.doi.org/10.1016/j.nmd.2017.06.009DOI Listing
September 2017

The role of microRNAs in the therapeutic action of D-cycloserine in a post-traumatic stress disorder animal model: an exploratory study.

Psychiatr Genet 2017 08;27(4):139-151

aDepartment of Psychiatry bDivision of Molecular Biology and Human Genetics, Stellenbosch University cSouth African Medical Research Council Bioinformatics Unit, South African National Bioinformatics Institute, University of the Western Cape, Cape Town dSchool of Physiology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg eCentre for Statistical Consultation, Stellenbosch University, Stellenbosch, South Africa.

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http://dx.doi.org/10.1097/YPG.0000000000000176DOI Listing
August 2017

A practical guide to filtering and prioritizing genetic variants.

Biotechniques 2017 01 1;62(1):18-30. Epub 2017 Jan 1.

South African National Bioinformatics Institute, University of the Western Cape, Bellville, South Africa.

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http://dx.doi.org/10.2144/000114492DOI Listing
January 2017

Identification of phenotype-relevant differentially expressed genes in breast cancer demonstrates enhanced quantile discretization protocol's utility in multi-platform microarray data integration.

J Bioinform Comput Biol 2016 10 13;14(5):1650022. Epub 2016 Jul 13.

1 South African National Bioinformatics Institute/MRC, Unit for Bioinformatics Capacity Development, University of the Western Cape, Private Bag X17, Bellville 7535, South Africa.

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http://dx.doi.org/10.1142/S0219720016500220DOI Listing
October 2016

Genome-Wide DNA Methylation in Mixed Ancestry Individuals with Diabetes and Prediabetes from South Africa.

Int J Endocrinol 2016 31;2016:3172093. Epub 2016 Jul 31.

Non-Communicable Diseases Research Unit, South African Medical Research Council, Cape Town 7505, South Africa; Department of Medicine, University of Cape Town, Cape Town 8000, South Africa.

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http://dx.doi.org/10.1155/2016/3172093DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4983374PMC
August 2016

Computational characterization of Iron metabolism in the Tsetse disease vector, Glossina morsitans: IRE stem-loops.

BMC Genomics 2016 08 8;17:561. Epub 2016 Aug 8.

South African Medical Research Council Bioinformatics Unit, The South African National Bioinformatics Institute (SANBI), University of the Western Cape, Robert Sobukwe Street, Bellville, South Africa.

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http://dx.doi.org/10.1186/s12864-016-2932-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4977773PMC
August 2016

Mycobacterium tuberculosis strains exhibit differential and strain-specific molecular signatures in pulmonary epithelial cells.

Dev Comp Immunol 2016 12 3;65:321-329. Epub 2016 Aug 3.

Medical Microbiology and Infection Control, School of Laboratory Medicine and Medical Sciences, College of Health Sciences, University of KwaZulu-Natal, South Africa. Electronic address:

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http://dx.doi.org/10.1016/j.dci.2016.07.022DOI Listing
December 2016

A new tool for prioritization of sequence variants from whole exome sequencing data.

Source Code Biol Med 2016 1;11:10. Epub 2016 Jul 1.

Division of Molecular Biology and Human Genetics, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa.

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http://dx.doi.org/10.1186/s13029-016-0056-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4929716PMC
July 2016

Canonical pathways, networks and transcriptional factor regulation by clinical strains of Mycobacterium tuberculosis in pulmonary alveolar epithelial cells.

Tuberculosis (Edinb) 2016 Mar 18;97:73-85. Epub 2015 Dec 18.

Medical Microbiology and Infection Control, School of Laboratory Medicine and Medical Sciences, College of Health Sciences, University of KwaZulu-Natal, 719 Umbilo Road, Private Bag 7, Congella 4013, Durban, South Africa. Electronic address:

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http://dx.doi.org/10.1016/j.tube.2015.12.002DOI Listing
March 2016

NetCapDB: measuring bioinformatics capacity development in Africa.

BMC Res Notes 2016 Mar 5;9:144. Epub 2016 Mar 5.

South African National Bioinformatics Institute/Medical Research Council of South Africa Bioinformatics Unit, University of the Western Cape, Cape Town, South Africa.

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http://dx.doi.org/10.1186/s13104-016-1950-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4779554PMC
March 2016

The Development of Computational Biology in South Africa: Successes Achieved and Lessons Learnt.

PLoS Comput Biol 2016 Feb 4;12(2):e1004395. Epub 2016 Feb 4.

South African National Bioinformatics Institute/Medical Research Council of South Africa Bioinformatics Unit, University of the Western Cape, Bellville, South Africa.

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http://dx.doi.org/10.1371/journal.pcbi.1004395DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4742231PMC
February 2016

Semantic interrogation of a multi knowledge domain ontological model of tendinopathy identifies four strong candidate risk genes.

Sci Rep 2016 Jan 25;6:19820. Epub 2016 Jan 25.

South African National Bioinformatics Institute/MRC Unit for Bioinformatics Capacity Development, University of the Western Cape, Bellville, South Africa.

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http://dx.doi.org/10.1038/srep19820DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4726433PMC
January 2016

Potential Broad Spectrum Inhibitors of the Coronavirus 3CLpro: A Virtual Screening and Structure-Based Drug Design Study.

Viruses 2015 Dec 15;7(12):6642-60. Epub 2015 Dec 15.

South African Medical Research Council Bioinformatics Capacity Development Unit, South African National Bioinformatics Institute, University of the Western Cape, Bellville 7535, South Africa.

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https://ai2-s2-pdfs.s3.amazonaws.com/ed52/6e1eb5a7607af28039
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http://www.mdpi.com/1999-4915/7/12/2963
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http://dx.doi.org/10.3390/v7122963DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4690886PMC
December 2015

Molecular mechanisms of D-cycloserine in facilitating fear extinction: insights from RNAseq.

Metab Brain Dis 2016 Feb 23;31(1):135-56. Epub 2015 Sep 23.

Department of Psychiatry, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa.

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http://dx.doi.org/10.1007/s11011-015-9727-4DOI Listing
February 2016

Human coronavirus OC43 3CL protease and the potential of ML188 as a broad-spectrum lead compound: homology modelling and molecular dynamic studies.

BMC Struct Biol 2015 Apr 28;15. Epub 2015 Apr 28.

South African National Bioinformatics Institute/ MRC Unit for Bioinformatics Capacity Development, University of the Western Cape, Bellville, South Africa.

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http://www.biomedcentral.com/1472-6807/15/8
Publisher Site
http://dx.doi.org/10.1186/s12900-015-0035-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4411765PMC
April 2015

Identification of new respiratory viruses in the new millennium.

Viruses 2015 Mar 6;7(3):996-1019. Epub 2015 Mar 6.

Molecular Biology and Virology Laboratory, Department of Medical BioSciences, Faculty of Natural Sciences, University of the Western Cape, Western Cape 7535, South Africa.

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http://www.mdpi.com/1999-4915/7/3/996
Publisher Site
http://dx.doi.org/10.3390/v7030996DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4379558PMC
March 2015

Self-similarity of human protein interaction networks: a novel strategy of distinguishing proteins.

Sci Rep 2015 Feb 27;5:7628. Epub 2015 Feb 27.

Department of Mathematics and Applied Mathematics, University of the Western Cape, P/Bag X17, Bellville, South Africa.

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http://dx.doi.org/10.1038/srep07628DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4342563PMC
February 2015

Research capacity. Enabling the genomic revolution in Africa.

Authors:
Charles Rotimi Akin Abayomi Alash'le Abimiku Victoria May Adabayeri Clement Adebamowo Ezekiel Adebiyi Adebowale D Ademola Adebowale Adeyemo Dwomoa Adu Dissou Affolabi Godfred Agongo Samuel Ajayi Sally Akarolo-Anthony Rufus Akinyemi Albert Akpalu Marianne Alberts Orlando Alonso Betancourt Ahmed Mansour Alzohairy Gobena Ameni Olukemi Amodu Gabriel Anabwani Kristian Andersen Fatiu Arogundade Oyedunni Arulogun Danny Asogun Rasheed Bakare Naby Balde Mary Lynn Baniecki Christine Beiswanger Alia Benkahla Lara Bethke Micheal Boehnke Vincent Boima James Brandful Andrew I Brooks Frank C Brosius Chester Brown Bruno Bucheton David T Burke Barrington G Burnett Stacy Carrington-Lawrence Nadia Carstens John Chisi Alan Christoffels Richard Cooper Heather Cordell Nigel Crowther Talishiea Croxton Jantina de Vries Leslie Derr Peter Donkor Seydou Doumbia Audrey Duncanson Ivy Ekem Ahmed El Sayed Mark E Engel John C K Enyaru Dean Everett Faisal M Fadlelmola Eyitayo Fakunle Kenneth H Fischbeck Anne Fischer Onikepe Folarin Junaid Gamieldien Robert F Garry Simani Gaseitsiwe Rasheed Gbadegesin Anita Ghansah Maria Giovanni Parham Goesbeck F Xavier Gomez-Olive Donald S Grant Ravnit Grewal Mark Guyer Neil A Hanchard Christian T Happi Scott Hazelhurst Branwen J Hennig Christiane Hertz- Fowler Winston Hide Friedhelm Hilderbrandt Christopher Hugo-Hamman Muntaser E Ibrahim Regina James Yasmina Jaufeerally-Fakim Carolyn Jenkins Ute Jentsch Pan-Pan Jiang Moses Joloba Victor Jongeneel Fourie Joubert Mukthar Kader Kathleen Kahn Pontiano Kaleebu Saidi H Kapiga Samar Kamal Kassim Ishmael Kasvosve Jonathan Kayondo Bernard Keavney Adeodata Kekitiinwa Sheik Humarr Khan Paul Kimmel Mary-Claire King Robert Kleta Mathurin Koffi Jeffrey Kopp Matthias Kretzler Judit Kumuthini Samuel Kyobe Catherine Kyobutungi Daniel T Lackland Karen A Lacourciere Guida Landouré Rita Lawlor Thomas Lehner Maia Lesosky Naomi Levitt Katherine Littler Zane Lombard Jeanne F Loring Sylvester Lyantagaye Annette Macleod Ebony B Madden Chengetai R Mahomva Julie Makani Manmak Mamven Marape Marape Graeme Mardon Patricia Marshall Darren P Martin Daniel Masiga Robin Mason Michael Mate-Kole Enock Matovu Mary Mayige Bongani M Mayosi Jean Claude Mbanya Sheryl A McCurdy Mark I McCarthy Helen McIlleron S O Mc'Ligeyo Corrine Merle Ana Olga Mocumbi Charles Mondo John V Moran Ayesha Motala Marva Moxey-Mims Wata Sununguko Mpoloka Chisomo L Msefula Thuli Mthiyane Nicola Mulder Gebregziab her Mulugeta Dieuodonne Mumba John Musuku Mo Nagdee Oyekanmi Nash Daouda Ndiaye Anh Quynh Nguyen Mark Nicol Oathokwa Nkomazana Shane Norris Betty Nsangi Alexander Nyarko Moffat Nyirenda Eileen Obe Reginald Obiakor Abraham Oduro Solomon F Ofori-Acquah Okechukwu Ogah Stephen Ogendo Kwaku Ohene-Frempong Akinlolu Ojo Timothy Olanrewaju John Oli Charlotte Osafo Odile Ouwe Missi Oukem-Boyer Bruce Ovbiagele Andrew Owen Mayowa Ojo Owolabi Lukman Owolabi Ellis Owusu-Dabo Guillaume Pare Rulan Parekh Hugh G Patterton Margaret B Penno Jane Peterson Rembert Pieper Jacob Plange-Rhule Martin Pollak Julia Puzak Rajkumar S Ramesar Michele Ramsay Rebekah Rasooly Shiksha Reddy Pardis C Sabeti Kwamena Sagoe Tunde Salako Oumar Samassékou Manjinder S Sandhu Osman Sankoh Fred Stephen Sarfo Marie Sarr Gasnat Shaboodien Issa Sidibe Gustave Simo Martin Simuunza Liam Smeeth Eugene Sobngwi Himla Soodyall Hermann Sorgho Oumou Sow Bah Sudha Srinivasan Dan J Stein Ezra S Susser Carmen Swanepoel Godfred Tangwa Andrew Tareila Ozlem Tastan Bishop Bamidele Tayo Nicki Tiffin Halidou Tinto Ekaete Tobin Stephen Meir Tollman Mahamadou Traoré Marsha J Treadwell Jennifer Troyer Masego Tsimako-Johnstone Vincent Tukei Ifeoma Ulasi Nzovu Ulenga Beverley van Rooyen Ablo Prudence Wachinou Salina P Waddy Alisha Wade Misaki Wayengera James Whitworth Louise Wideroff Cheryl A Winkler Sarah Winnicki Ambroise Wonkam Mengistu Yewondwos Tadase sen Nathan Yozwiak Heather Zar

Science 2014 Jun;344(6190):1346-8

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http://dx.doi.org/10.1126/science.1251546DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4138491PMC
June 2014

Modelling human protein interaction networks as metric spaces has potential in disease research and drug target discovery.

BMC Syst Biol 2014 Jun 14;8:68. Epub 2014 Jun 14.

South African National Bioinformatics Institute/ MRC Unit for Bioinformatics Capacity Development, University of the Western Cape, Bellville 7530, South Africa.

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http://dx.doi.org/10.1186/1752-0509-8-68DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4088370PMC
June 2014

Protein interaction networks as metric spaces: a novel perspective on distribution of hubs.

BMC Syst Biol 2014 Jan 18;8. Epub 2014 Jan 18.

Department of Mathematics and Applied Mathematics, University of the Western Cape, P/Bag X17, Bellville, South Africa.

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http://dx.doi.org/10.1186/1752-0509-8-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3902029PMC
January 2014

The African coelacanth genome provides insights into tetrapod evolution.

Nature 2013 Apr;496(7445):311-6

Molecular Genetics Program, Benaroya Research Institute, Seattle, Washington 98101, USA.

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http://dx.doi.org/10.1038/nature12027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3633110PMC
April 2013

Positive selection scanning reveals decoupling of enzymatic activities of carbamoyl phosphate synthetase in Helicobacter pylori.

J Mol Evol 2002 Apr;54(4):458-64

Department of Biochemistry and Biophysics and Stockholm Bioinformatics Center, Stockholm University, 10691 Stockholm, Sweden.

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http://dx.doi.org/10.1007/s00239-001-0029-6DOI Listing
April 2002

Eukaryotic genes in Mycobacterium tuberculosis could have a role in pathogenesis and immunomodulation.

Trends Genet 2002 Jan;18(1):5-8

South African National Bioinformatics Institute, University of the Western Cape, Private Bag X17, Bellville, 7535South Africa.

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http://dx.doi.org/10.1016/s0168-9525(01)02529-xDOI Listing
January 2002