Publications by authors named "Jun-Su Kim"

20 Publications

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Effect of exercise immersion experience on health promotion and lifelong physical education of high school students in sports club activities.

J Exerc Rehabil 2021 Jun 30;17(3):169-174. Epub 2021 Jun 30.

Department of Sports and Outdoors, College of Bio Convergence, Eulji University, Seongnam, Korea.

The purpose of this study was to investigate the impact of high school students' athletic commitment, health promotion education, and lifelong sports activities. To this end, the researcher searched for research subjects of 397 high school students residing in Seoul in 2019. As a result of the analysis, the following conclusions were drawn. First, the effect of exercise commitment on sports health promotion education was investigated. Looking at the activities of high school students, their commitment to behavior has had a profound impact on their health responsibilities and relationships. Second, the study also investigated the impact of athletic commitment to lifelong sports of sports activities in high school students and found that cognitive and behavioral commitment had a significant impact on lifelong sports. Finally, as a result of investigating the impact of health promotion education on lifelong sports of high school student sports activities, it was found that health responsibility and relationships have a great influence on lifelong sports.
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http://dx.doi.org/10.12965/jer.2142284.142DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8257431PMC
June 2021

Self-esteem and social development according to participation in school sports club.

J Exerc Rehabil 2021 Jun 30;17(3):164-168. Epub 2021 Jun 30.

Department of Sports and Outdoors, College of Bio Convergence, Eulji University, Seongnam, Korea.

The purpose of this study is to explore the meaning of the middle school sports club and to understand the impact on the self-esteem and social development of middle school students participating in the school sports club. To achieve the purpose of this study, a questionnaire survey was conducted on 450 students by selecting a middle school. Of the 420 collected questionnaires, 399 questionnaires were used as a valid sample. As a result of examining seven areas of self-esteem, self-esteem in five areas excluding domestic ego and personality ego was highest in the group that participated in the league. As a result of examining the difference in social development according to the type of participation in school sports clubs, the league participation group was higher in all five areas. As a result of examining the difference in self-esteem according to the period of participation in school sports clubs, the group participating in the league was high in six areas excluding physical ability, however, it was difficult to see a statistically significant difference. As for the factor related to physical ability, the group with the longest participation period of 13 months or longer was the highest, and there is a statistically significant difference. As a result of examining the difference in social development according to the period of participation in school sports clubs, the group under 6 months was the highest in four areas other than physical activity. Physical activity was highest in the group over 13 months.
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http://dx.doi.org/10.12965/jer.2142286.143DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8257438PMC
June 2021

Effects of Kinesio taping on blood fatigue factors after isokinetic exercise.

J Exerc Rehabil 2021 Apr 27;17(2):145-149. Epub 2021 Apr 27.

Department of Sports and Outdoors, College of Bio Convergence, Eulji University, Seongnam, Korea.

This study examined the effects of Kinesio taping on recovery from fatigue induced by an exercise of concentric contraction using an isokinetic machine. Eight healthy collegiate students participated in two experiments: the Kinesio taping application condition and the no Kinesio taping application condition. The fatigue was induced by concentric exercise at 60°/sec, 50 repetitions for one session, and repeated 3 sessions. Changes of blood ammonia, lactate, lactate dehydrogenase (LDH), and creatinine kinase (CK) were monitored. Blood was collected before exercise, immediately after exercise, 24 hr after exercise, and 72 hr after exercise. Blood ammonia tended to reduce during the recovery process, but no differences were found between conditions. Blood lactate tended to reduce during the recovery process, but no differences were found between conditions. In the blood LDH, no differences were found between conditions. Blood creatine kinase tended to reduce during the recovery process, but no differences were found between conditions. The present results showed that Kinesio taping did not affect the recovery phase of blood ammonia, lactate concentration, LDH, and CK.
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http://dx.doi.org/10.12965/jer.2142186.093DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8103188PMC
April 2021

Identification of galectin‑10 as a biomarker for periodontitis based on proteomic analysis of gingival crevicular fluid.

Mol Med Rep 2021 02 10;23(2). Epub 2020 Dec 10.

Department of Dental Hygiene, College of Health Science, Eulji University, Seongnam, Gyeonggi 13135, Republic of Korea.

Periodontitis is a chronic inflammatory disease caused by the gradual breakdown of tissues surrounding the teeth due to various factors. The disease has been frequently noted in dental outpatients for a number of years. Improvements are required to current diagnostic methods, which have limitations in assessing the condition and progression of periodontitis. The development of diagnostic biomarkers for periodontitis to increase the sensitivity and accuracy of diagnosis is important for the management of periodontitis. In the present study, whole gingival crevicular fluid (GCF) from patients with periodontitis and healthy individuals was characterized via liquid chromatography with tandem mass spectrometry. Label‑free quantification was used to identify the differentially abundant protein biomarkers. A total of 1,295 proteins were identified from the whole GCF of patients with periodontitis and healthy individuals via proteomic analysis. When analyzing biological processes, 'metabolic process' and 'cell organization and biogenes' were identified to play important roles in GCF under periodontitis conditions according to Gene Ontology. When analyzing molecular functions, 'catalytic activity' and 'protein binding' were the terms most enriched with differentially abundant proteins under periodontitis conditions. Galectin‑10 (Gal‑10) was one of the most upregulated proteins in the GCF of patients with periodontitis. The levels of prostaglandin E2 were increased in oral keratinocytes and gingival fibroblasts treated with recombinant (r)Gal‑10. The levels of interleukin‑8, matrix metalloproteinase 9 and C‑reactive protein were increased in the conditioned media (CM) of rGal‑10‑treated gingival fibroblasts. In addition, the CM of rGal‑10‑treated gingival fibroblasts induced osteoclast differentiation. These results suggested that Gal‑10 expression was increased in the GCF of patients with periodontitis and contributed to the process of osteoclastogenesis. Therefore, Gal‑10 may be a candidate biomarker for periodontitis.
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http://dx.doi.org/10.3892/mmr.2020.11762DOI Listing
February 2021

Swimming Exercise Ameliorates Symptoms of MOG-Induced Experimental Autoimmune Encephalomyelitis by Inhibiting Inflammation and Demyelination in Rats.

Int Neurourol J 2020 May 31;24(Suppl 1):S39-47. Epub 2020 May 31.

Department of Physiology, College of Medicine, Kyung Hee University, Seoul, Korea.

Purpose: Multiple sclerosis is an autoimmune disease that affects the central nerve system, resulting in cumulative loss of motor function. Multiple sclerosis is induced through multiple mechanisms and is caused by inflammation and demyelination. This study aims to evaluate the neuroprotective effect of swimming exercise in experimental autoimmune encephalomyelitis (EAE) rats, an animal model of multiple sclerosis.

Methods: EAE was induced by an intradermal injection of 50-μg purified myelin oligodendrocyte glycoprotein 33-55 (MOG33-55) dissolved in 200-μL saline at the base of the tail. The rats in the swimming exercise group were made to swim for 30 minutes once pert a day for 26 consecutive days, starting 5 days after induction of EAE. To compare the effect of swimming exercise with interferon-β, a drug for multiple sclerosis, interferon-β was injected intraperitoneally into rats of the EAE-induced and interferon-β-treated group during the exercise period.

Results: Injection of MOG33-55 caused weight loss, decreased clinical disability score, and increased level of pro-inflammatory cytokines and inflammatory mediators in the lumbar spinal cord. Loss of motor function and weakness increased demyelination score. Swimming exercise suppressed demyelination and expression of pro-inflammatory cytokines and inflammatory mediators. These changes promoted recovery of EAE symptoms such as body weight loss, motor dysfunction, and weakness. Swimming exercise caused the same level of improvement as interferon-β treatment.

Conclusion: The results of this experiment suggest the possibility of swimming exercise in urological diseases that are difficult to treat. Swimming exercises can be considered for relief of symptom in incurable multiple sclerosis.
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http://dx.doi.org/10.5213/inj.2040156.078DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7285701PMC
May 2020

Effects of whole-body vibration exercise on functions required for bowling performance of male bowling player.

Authors:
Jun-Su Kim

J Exerc Rehabil 2019 Feb 25;15(1):78-87. Epub 2019 Feb 25.

Department of Kinesiology, Inha University, Incheon, Korea.

The focus of this research is to examine the impact of 8 weeks of whole body vibration (WBV) exercise on physical factors by conducting an experiment on 17 male bowling players registered in Korea Bowling Association. Strength of truncus and lower-limb and balance were mea-sured as the physical factors and the impact of WBV exercise on each variable was examined. There was significant increase between groups in flexor-weight ratio of truncus at 60°/sec according to performance after applying WBV exercise. There was significant difference in groups before bowling event in pre and posttest as well as after bowling event in pre and posttest. There was significant difference of extensor-weight ratio in groups after bowling event in pre and posttest. There was significant increase at 60°/sec in flexor-ratio of both left and right lower-limb strength according to performance after applying WBV exercise. There was significant difference between groups before bowling event in pre and posttest as well as after bowling event in pre and posttest. Extensor-weight ratio showed significant difference between groups only before bowling event in pre and posttest. There was significant difference between groups in both left and right balance according to performance after applying WBV exercise. There was significant difference in before bowling event in pre and posttest as well as after bowling event in pre and posttest.
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http://dx.doi.org/10.12965/jer.1938038.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6416501PMC
February 2019

Correction: The Effect of Lifestyle Changes on Blood Pressure Control among Hypertensive Patients.

Korean J Fam Med 2017 Sep 22;38(5):311-312. Epub 2017 Sep 22.

Department of Family Medicine, Pusan National University Yangsan Hospital, Pusan National University School of Medicine, Yangsan, Korea.

[This corrects the article on p. 173 in vol. 38, PMID: 28775806.].
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http://dx.doi.org/10.4082/kjfm.2017.38.5.311DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5637225PMC
September 2017

The Effect of Lifestyle Changes on Blood Pressure Control among Hypertensive Patients.

Korean J Fam Med 2017 Jul 20;38(4):173-180. Epub 2017 Jul 20.

Department of Family Medicine, Pusan National University Yangsan Hospital, Pusan National University School of Medicine, Yangsan, Korea.

Background: Hypertension is highly prevalent among patients who visit primary care clinics. Various factors and lifestyle behaviors are associated with effective blood pressure control. We aimed to identify factors and lifestyle modifications associated with blood pressure control among patients prescribed antihypertensive agents.

Methods: This survey was conducted at 15 hospital-based family practices in Korea from July 2008 to June 2010. We prospectively recruited and retrospectively assessed 1,453 patients prescribed candesartan. An initial evaluation of patients' lifestyles was performed using individual questions. Follow-up questionnaires were administered at 4, 8, and 12 weeks. We defined successful blood pressure control as blood pressure <140 mm Hg systolic and <90 mm Hg diastolic.

Results: Of the 1,453 patients, 1,139 patients with available data for initial and final blood pressures were included. In the univariate analysis of the change in performance index, weight gain (odds ratio [OR], 2.18; 95% confidence interval [CI], 1.52 to 3.11; P<0.001), physical inactivity (OR, 1.195; 95% CI, 1.175 to 3.387; P=0.011), and increased salt intake (OR, 1.461; 95% CI, 1.029 to 2.075; P=0.034) were related to inadequate blood pressure control. Salt intake also showed a significant association. Multivariate ORs were calculated for age, sex, body mass index, education, income, alcohol consumption, smoking status, salt intake, comorbidity, and family history of hypertension. In the multivariate analysis, sex (OR, 3.55; 95% CI, 2.02 to 6.26; P<0.001), salt intake (OR, 0.64; 95% CI 0.43 to 0.97; P=0.034), and comorbidity (OR, 1.82; 95% CI, 1.23 to 2.69; P=0.003) were associated with successful blood pressure control.

Conclusion: Weight gain, physical inactivity, and high salt intake were associated with inadequate blood pressure control.
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http://dx.doi.org/10.4082/kjfm.2017.38.4.173DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5541164PMC
July 2017

SEARCH 8Es: A novel point of care ultrasound protocol for patients with chest pain, dyspnea or symptomatic hypotension in the emergency department.

PLoS One 2017 29;12(3):e0174581. Epub 2017 Mar 29.

Department of Emergency Medicine, Bundang Jesaeng General Hospital, Sungnam, Republic of Korea.

Objective: This study was conducted to evaluate a problem-oriented focused torso bedside ultrasound protocol termed "Sonographic Evaluation of Aetiology for Respiratory difficulty, Chest pain, and/or Hypotension" (SEARCH 8Es) for its ability to narrow differential diagnoses and increase physicians' diagnostic confidence, and its diagnostic accuracy, for patients presenting with dyspnea, chest pain, or symptomatic hypotension.

Methods: This single-center prospective observational study was conducted over 12 months in an emergency department and included 308 patients (184 men and 124 women; mean age, 67.7 ± 19.1 years) with emergent cardiopulmonary symptoms. The paired t-test was used to compare the number of differential diagnoses and physician's level of confidence before and after SEARCH 8Es. The overall accuracy of the SEARCH 8Es protocol in differentiating 13 diagnostic entities was evaluated based on concordance (kappa coefficient) with the diagnosis made by the inpatient specialists. Sensitivity, specificity, positive predictive value, and negative predictive value were calculated.

Results: SEARCH 8Es narrows the number of differential diagnoses (2.5 ± 1.5 vs. 1.4 ± 0.7; p < 0.001) and improves physicians' diagnostic confidence (2.8 ± 0.8 vs. 4.3 ± 0.9; p < 0.001) significantly. The overall kappa coefficient value was 0.870 (p < 0.001), with the overall sensitivity, specificity, positive predictive value, and negative predictive value at 90.9%, 99.0%, 89.7%, and 99.0%, respectively.

Conclusion: The SEARCH 8Es protocol helps emergency physicians to narrow the differential diagnoses, increase diagnostic confidence and provide accurate assessment of patients with dyspnea, chest pain, or symptomatic hypotension.
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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0174581PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5371336PMC
September 2017

Association between Obesity and Neighborhood Socioeconomic Status in Korean Adolescents Based on the 2013 Korea Youth Risk Behavior Web-Based Survey.

Korean J Fam Med 2016 Jan 27;37(1):64-70. Epub 2016 Jan 27.

Department of Family Medicine, Inje University Busan Paik Hospital, Inje University College of Medicine, Busan, Korea.

Background: An increase in the obese adolescent population is being recognized as a serious medical and social problem. The present study aimed to examine the association between neighborhood socioeconomic status (SES) and obesity in Korean adolescents based on total available resources and local social inequality models.

Methods: The present study used data from the 2013 Korea Youth Risk Behavior Web-based Survey in analyzing 72,438 Korean adolescents aged 12-18. The analysis investigated obesity odds ratio (OR) according to neighborhood SES adjusted for age and individual SES indices, which included family affluence scale (FAS), education level of parents, cohabitation with parents, and weekly allowance. Obesity OR was investigated according to neighborhood SES by FAS, and according to FAS by neighborhood SES.

Results: After adjusting for age and individual SES variables, there was no significant association between neighborhood SES and adolescent obesity for either boys or girls. However, girls in the high FAS group showed a pattern of lower neighborhood SES being associated with a significant increase in risk of obesity; in the high neighborhood SES group, boys showed a pattern of higher FAS being associated with a significant increase in risk of obesity, whereas girls show a pattern of decrease.

Conclusion: Although limited, the present study demonstrated that some girl groups exhibited a pattern of lower neighborhood SES being associated with an increase in risk of obesity, as well as a gender-based difference in risk of obesity by individual SES. Therefore, measures to prevent adolescent obesity should be established with consideration for differences in risk according to individual and neighborhood SES.
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http://dx.doi.org/10.4082/kjfm.2016.37.1.64DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4754289PMC
January 2016

Endovascular revascularization for patients with critical limb ischemia: impact on wound healing and long term clinical results in 189 limbs.

Korean J Radiol 2013 May-Jun;14(3):430-8. Epub 2013 May 2.

Department of Radiology, Ajou University School of Medicine, Suwon 443-721, Korea.

Objective: To evaluate the impact on wound healing and long-term clinical outcomes of endovascular revascularization in patients with critical limb ischemia (CLI).

Materials And Methods: This is a retrospective study on 189 limbs with CLI treated with endovascular revascularization between 2008 and 2010 and followed for a mean 21 months. Angiographic outcome was graded to technical success (TS), partial failure (PF) and complete technical failure. The impact on wound healing of revascularization was assessed with univariate analysis and multivariate logistic regression models. Analysis of long-term event-free limb survival, and limb salvage rate (LSR) was performed by Kaplan-Meier method.

Results: TS was achieved in 89% of treated limbs, whereas PF and CF were achieved in 9% and 2% of the limbs, respectively. Major complications occurred in 6% of treated limbs. The 30-day mortality was 2%. Wound healing was successful in 85% and failed in 15%. Impact of angiographic outcome on wound healing was statistically significant. The event-free limb survival was 79.3% and 69.5% at 1- and 3-years, respectively. The LSR was 94.8% and 92.0% at 1- and 3-years, respectively.

Conclusion: Endovascular revascularization improve wound healing rate and provide good long-term LSRs in CLI.
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http://dx.doi.org/10.3348/kjr.2013.14.3.430DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3655296PMC
April 2014

Differential association of adiposity measures with heart rate variability measures in Koreans.

Yonsei Med J 2013 Jan;54(1):55-61

School of Computer Aided Science & Institute of Basic Science, Inje University, Gimhae, Korea.

Purpose: Although obesity has been associated with imbalances in cardiac autonomic nervous system, it is unclear whether there are differential relationships between adiposity measures and heart rate variability (HRV) measures. We aimed to examine differences in the relationship between adiposity measures and HRV indices in a healthy Korean population.

Materials And Methods: In all, 1409 non-smokers (811 males, 598 females) without known histories of cardiovascular (CV), endocrine, or neurological diseases underwent adiposity measurements [(body mass index (BMI), percentage of body fat mass (PBF), and waist-to-hip ratio (WHR)], the HRV assessment (SDNN, RMSSD, LF, HF, LF/HF, and pNN50), and examination for CV risk factors (fasting glucose, LDL-cholesterol, HDL-cholesterol, triglycerides, hs-CRP, and blood pressure).

Results: Compared with BMI and PBF, WHR was more strongly correlated with each HRV index and more likely to predict decreased HRV (<15 percentile vs. ≥ 15 percentile of each HRV index) in ROC curves analysis. In linear regression analysis, all adiposity measures were inversely associated with each HRV measure before adjusting for age, gender, and CV risk factors (p<0.05). After adjusting for the covariates, WHR was inversely related to RMSSD, LF, and pNN50; PBF with RMSSD, HF, and pNN50; BMI with RMSSD (p<0.05). The inversed association between HRV indices and the gender-specific WHR tertile was significant for subjects with BMI ≥ 25 kg/m(2), but not for those with BMI <25 kg/m(2).

Conclusion: WHR and PBF appear to be better indicators for low HRV than BMI, and the association between abdominal adiposity and HRV may be stronger in overweight subjects.
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http://dx.doi.org/10.3349/ymj.2013.54.1.55DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3521274PMC
January 2013

Association between waist-to-height ratio and metabolic risk factors in Korean adults with normal body mass index and waist circumference.

Tohoku J Exp Med 2012 09;228(1):1-8

Health Screening Center, Kangbuk Samsung Hospital, Sungkyunkwan University, School of Medicine, Suwon, Korea.

There is little consensus on the best obesity index associated with metabolic risk factors among the population with normal both body mass index (BMI) and waist circumference (WC). We therefore evaluated the association between anthropometric indices and metabolic risk factors in a Korean population with normal BMI and WC. This cross-sectional study involved 2,952 participants aged 20-79 years who had normal BMI and WC, based on the Fourth Korea National Health and Nutrition Examination Surveys conducted in 2008. The receiver operating characteristic (ROC) curves were generated to identify the optimal measurement of obesity for the prediction of metabolic risk factors in this population. The area under the ROC curve value for waist-to-height ratio (WHtR) in prediction of metabolic syndrome (MetS) and its components was higher than that for BMI and WC. Among individuals with normal BMI and WC, prevalence of all metabolic risk factors and MetS significantly increased across the quartiles of WHtR in both men and women. After adjustment for potential confounders, the Odds Ratios (95% confidence intervals) for MetS in the second, third, and fourth quartiles of WHtR compared to the first quartile of WHtR were 3.53 (2.12-5.89), 6.06 (3.52-10.43), and 7.11 (4.08-12.38) in men, and 1.66 (1.01-2.72), 2.79 (1.81-4.30), and 2.82 (1.76-4.52) in women, respectively. In conclusion, WHtR has the best predictive value for evaluating the metabolic risk factors compared to BMI or WC alone among subjects with normal BMI and WC.
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http://dx.doi.org/10.1620/tjem.228.1DOI Listing
September 2012

Association of heart rate variability with the framingham risk score in healthy adults.

Korean J Fam Med 2011 Sep 28;32(6):334-40. Epub 2011 Sep 28.

School of Computer Aided Science & Institute of Basic Science, Inje University, Gimhae, Korea.

Background: The aim of this study was to investigate the relationship between heart rate variability (HRV), the Framingham risk score (FRS), and the 10-year risk of coronary heart disease (CHD) development among Korean adults.

Methods: The subjects were 85 healthy Korean adults recruited from a health check-up center. The FRS and 10-year risk of CHD development were calculated.

Results: The FRS in men was inversely correlated with the standard deviation of all normal to normal RR-intervals (SDNN); the root mean square successive difference (RMSSD); the percentage of successive normal cardiac inter-beat intervals greater than 20 ms, 30 ms, and 50 ms (pNN20, pNN30, pNN50); the low frequency (LF); and the high frequency (HF) (P < 0.05). There was no significant relationship between the FRS and HRV in women. Overall, in the receiver operating characteristic (ROC) analysis, the RMSSD, HF, SDNN, LF, LF/HF ratio, and pNN30 predicted an increased 10-year CHD risk. After adjusting for sex and body mass index, those with greater than one standard deviation in the RMSSD, HF, and LF had a 52-59% reduction in their 10-year risk of CHD development ≥ 10%.

Conclusion: This study therefore indicates that the HRV indices, particularly SDNN, RMSSD, pNN30, LF, and HF may be useful parameters for the assessment of CHD risk. Most notably, the usefulness of these HRV measures as indicators for CHD risk evaluation may be greater among men than among women.
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http://dx.doi.org/10.4082/kjfm.2011.32.6.334DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3383143PMC
September 2011

Factors Associated with Depressive Symptom in Chronic Obstructive Pulmonary Disease Based on the Third (2005) and Fourth (2008) Korea National Health and Nutritional Examination Survey (KNHANES III, IV).

Korean J Fam Med 2011 May 31;32(4):234-42. Epub 2011 May 31.

Department of Family Medicine, Busan Paik Hospital, Inje University College of Medicine, Busan, Korea.

Background: Depressive symptoms accompanied by chronic obstructive pulmonary disease (COPD) can be influenced by socioeconomic status, associated chronic diseases and the current smoking status. This study was conducted to assess factors that are associated with depressive symptoms accompanied by COPD, using the data obtained from the Korea National Health and Nutritional Survey (KNHANES) conducted in 2005 and 2008.

Methods: From the third (2005) and the fourth (2008) KNHANES, 407 (0.9%) with physician-diagnosed COPD were selected. Of the 407 subjects, only 180 (0.4%) who reported having depressive symptoms were included in this study. The associations of depressive symptoms with socioeconomic status, associated chronic diseases and smoking status were investigated.

Results: Of the total 180 subjects, 45 (25%) had depressive symptoms. There were 102 males (55%) and 78 females (45%) with a slight predilection for males. In multivariate analysis, significant predictors of depressive symptoms were dependent activities of daily living (odds ratio [OR], 2.42; 95% confidence interval [CI], 2.06 to 2.84) and association with number of chronic diseases (OR of one, two, and three, 1.40, 1.72, 2.60; 95% CI of one, two, and three, 1.20 to 1.63,1.41 to 2.10,1.99 to 3.39).

Conclusion: This study provides the basis for managing COPD patients in a clinical setting by understanding the number and characteristics of COPD patients with depressive symptoms. The results of this study suggest that primary physicians should manage COPD patients with consideration of risk factors for depressive symptom.
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http://dx.doi.org/10.4082/kjfm.2011.32.4.234DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3383134PMC
May 2011

Evaluation of changes in effluent quality from industrial complexes on the Korean nationwide scale using a self-organizing map.

Int J Environ Res Public Health 2012 04 11;9(4):1182-200. Epub 2012 Apr 11.

Department of Biology, Kyung Hee University, Dongdaemun, Seoul 130-701, Korea.

One of the major issues related to the environment in the 21st century is sustainable development. The innovative economic growth policy has supported relatively successful economic development, but poor environmental conservation efforts, have consequently resulted in serious water quality pollution issues. Hence, assessments of water quality and health are fundamental processes towards conserving and restoring aquatic ecosystems. In this study, we characterized spatial and temporal changes in water quality (specifically physico-chemical variables plus priority and non-priority pollutants) of discharges from industrial complexes on a national scale in Korea. The data were provided by the Water Quality Monitoring Program operated by the Ministry of Environment, Korea and were measured from 1989 to 2008 on a monthly basis at 61 effluent monitoring sites located at industrial complexes. Analysis of monthly and annual changes in water quality, using the seasonal Mann-Kendall test, indicated an improvement in water quality, which was inferred from a continuous increase in dissolved oxygen and decrease in other water quality factors. A Self-Organizing Map, which is an unsupervised artificial neural network, also indicated an improvement of effluent water quality, by showing spatial and temporal differences in the effluent water quality as well as in the occurrence of priority pollutants. Finally, our results suggested that continued long-term monitoring is necessary to establish plans and policies for wastewater management and health assessment.
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http://dx.doi.org/10.3390/ijerph9041182DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3366607PMC
April 2012

Obesity phenotype and coronary heart disease risk as estimated by the Framingham risk score.

J Korean Med Sci 2012 Mar 23;27(3):243-9. Epub 2012 Feb 23.

Department of Family Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.

There are conflicting data as to whether general or abdominal obesity is a better predictor of cardiovascular risk. This cross-sectional study involved 4,573 subjects aged 30 to 74 yr who participated in the Fourth Korea National Health and Nutrition Examination Survey conducted in 2008. Obesity phenotype was classified by means of body mass index (BMI) and waist circumference (WC), and participants were categorized into 4 groups. Individuals' 10-yr risk of coronary heart diseases (CHD) was determined from the Framingham risk score. Subjects with obese WC had a higher proportion of high risk for CHD compared to the normal WC group, irrespective of BMI level. Relative to subjects with normal BMI/normal WC, the adjusted odds ratios (ORs) of normal BMI/obese WC group (OR 2.93 [1.70, 5.04] and OR 3.10 [1.49, 6.46]) for CHD risk in male were higher than obese BMI/obese WC group (OR 1.91 [1.40, 2.61] and OR 1.70 [1.16, 2.47]), whereas the adjusted ORs of obese BMI/obese WC group (OR 1.94 [1.24, 3.04] and OR 3.92 [1.75, 8.78]) were higher than the others in female. Subjects with obese BMI/normal WC were not significantly associated with 10-yr CHD risk in men (P = 0.449 and P = 0.067) and women (P = 0.702 and P = 0.658). WC is associated with increased CHD risk regardless of the level of BMI. Men with normal BMI and obese WC tend to be associated with CHD risk than those with obese BMI and obese WC.
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http://dx.doi.org/10.3346/jkms.2012.27.3.243DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3286769PMC
March 2012

Association between metabolic syndrome and estimated glomerular filtration rate in older Koreans based on data from the third Korean National Health and Nutrition Examination Survey.

Australas J Ageing 2011 Mar;30(1):16-21

Department of Family Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.

Aim: To examine the association between metabolic syndrome (MetS) and renal function in older Koreans.

Methods: A total of 1270 people aged 60 years and older who participated in the third Korean National Health and Nutrition Examination Survey were included in this study.

Results: After adjusting for confounding factors, central obesity, high-density lipoprotein cholesterol and fasting glucose were significantly associated with decreased renal function in men. In women, however, each component of MetS with the exception of fasting glucose was not associated with renal function. The odds ratios for MetS were 2.548 in men and 1.454 in women after adjustment for confounding variables; both were statistically significant. The odds ratio of decreased renal function increased as the number of components of MetS increased.

Conclusion: The results of this study suggest that MetS may be an independent risk factor for decreased renal function in older population as well.
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http://dx.doi.org/10.1111/j.1741-6612.2010.00440.xDOI Listing
March 2011

Association between metabolic syndrome and estimated glomerular filtration rate in older Koreans based on data from the third Korean National Health and Nutrition Examination Survey.

Australas J Ageing 2011 Mar;30(1):16-21

Department of Family Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.

Aim: To examine the association between metabolic syndrome (MetS) and renal function in older Koreans.

Methods: A total of 1270 people aged 60 years and older who participated in the third Korean National Health and Nutrition Examination Survey were included in this study.

Results: After adjusting for confounding factors, central obesity, high-density lipoprotein cholesterol and fasting glucose were significantly associated with decreased renal function in men. In women, however, each component of MetS with the exception of fasting glucose was not associated with renal function. The odds ratios for MetS were 2.548 in men and 1.454 in women after adjustment for confounding variables; both were statistically significant. The odds ratio of decreased renal function increased as the number of components of MetS increased.

Conclusion: The results of this study suggest that MetS may be an independent risk factor for decreased renal function in older population as well.
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http://dx.doi.org/10.1111/j.1741-6612.2010.00440.xDOI Listing
March 2011

The roles of obesity and gender on the relationship between metabolic risk factors and non-alcoholic fatty liver disease in Koreans.

Diabetes Metab Res Rev 2009 Feb;25(2):150-5

Department of Family Medicine, Busan Paik Hospital, Inje University College of Medicine, Jin-Gu, Busan, Korea.

Background: The effect of gender and weight status on the association between metabolic risk factors and NAFLD has not been well established. This study aimed to assess the relationships among obesity, gender, metabolic risk factors, and non-alcoholic fatty liver disease (NAFLD) in Korean adults.

Methods: Abdominal ultrasounds, anthropometric measurements, and biochemical tests were performed on 13,768 Korean adults (7,313 men and 6,455 women) recruited from a health promotion centre between 2005 and 2006.

Results: Of 13,768 subjects, 25% were diagnosed with NAFLD. Weight status (obesity vs non-obesity, odds ratio (OR) 4.4-9.7) and gender (women vs men, OR 0.6) were associated with NAFLD after adjusting for age, metabolic risk factors (high blood pressure, high glucose, high TG, low HDL, high LDL, and high uric acid), and gamma-glutamyl transferase (gammaGT). For subjects with any one risk factor, the OR (95% CI) for mild fatty liver was 27 (19.3-37.8) in men and 7.9 (6.1-10.2) in women who were obese compared to non-obese individuals having no risk factors. The ORs in men and women who were not obese were 4.7 (3.9-5.6) and 2.5 (2.2-3.0), respectively. The sensitivity and specificity for NAFLD with any one risk factor without obesity was 90-91 and 32-49%, respectively; any one risk factor combined with obesity changed the sensitivity and specificity to 64-67 and 77-85%, respectively.

Conclusions: Gender and weight status appear to modify the relationship between metabolic risk factors and NAFLD.
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http://dx.doi.org/10.1002/dmrr.924DOI Listing
February 2009
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