Publications by authors named "Jun-Ming Liang"

2 Publications

  • Page 1 of 1

[Advances on chemical constituents of Tibetan Salvia genus].

Zhongguo Zhong Yao Za Zhi 2017 Oct;42(19):3684-3695

College of Pharmacy and Biological Engineering, Chengdu University, Chengdu 610106, China.

Salvia is the largest genus of Labiatae family, and there are more than 1 000 species around the world. Our country is rich in the resources of Salvia plants. The plants of this genus contain multiple chemical components, including sesquiterpenoids, diterpenoids, triterpenoids and phenols, et al. In order to develop better Tibetan plants of Salvia genus, this article reviewed and summarized the constituents from Tibetan Salvia genus.
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October 2017

Clemochinenosides C and D, two new macrocyclic glucosides from Clematis chinensis.

J Asian Nat Prod Res 2018 Nov 23;20(11):1038-1044. Epub 2017 Oct 23.

a College of Pharmacy and Bioengineering , Chengdu University , Chengdu 610106 , China.

The EtOH extract of the roots and rhizomes of Clematis chinensis afforded two new macrocyclic glucosides clemochinenosides C (1) and D (2). Their structures were elucidated on the basis of spectroscopic means and hydrolysis products. These compounds were evaluated for inhibitory activity against lipopolysaccharides-induced TNF-α production in RAW 246.7 macrophages. Compounds 1 and 2 showed moderate inhibitory activity with IC values of 12.9 ± 2.3 and 18.4 ± 2.7 μM, respectively. In addition, a proliferation study was used to evaluate the anti-angiogenic effects of these compounds in vitro (VEGF-induced human umbilical vein endothelial cell proliferation). Compounds 1 and 2 displayed weak inhibitory effects with inhibition rates of 26.3 ± 1.8 and 19.2 ± 2.6% at 50 μM, respectively.
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November 2018